Detailed information for compound 784657

Basic information

Technical information
  • TDR Targets ID: 784657
  • Name: STK056797
  • MW: 323.281 | Formula: C12H9N3O6S
  • H donors: 1 H acceptors: 6 LogP: 2.1 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: [O-][N+](=O)c1cccc(c1)NS(=O)(=O)c1ccccc1[N+](=O)[O-]
  • InChi: 1S/C12H9N3O6S/c16-14(17)10-5-3-4-9(8-10)13-22(20,21)12-7-2-1-6-11(12)15(18)19/h1-8,13H
  • InChiKey: NJRYOYUOLUFJPO-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • ZINC03150108

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0068 0.0682 0.2655
Brugia malayi hypothetical protein 0.0016 0.0059 0.0249
Brugia malayi hypothetical protein 0.0035 0.0282 0.1183
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0427 0.2146
Loa Loa (eye worm) hypothetical protein 0.0212 0.2385 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0066 0.0065
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.0113 0.0475
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0282 0.1417
Brugia malayi latrophilin 2 splice variant baaae 0.0145 0.1589 0.6661
Loa Loa (eye worm) hypothetical protein 0.0021 0.0113 0.0205
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0067 0.0665 0.2787
Echinococcus multilocularis zinc finger protein 0.0021 0.0114 0.0113
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.0113 0.0112
Loa Loa (eye worm) hypothetical protein 0.0021 0.0113 0.0205
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0427 0.2146
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0295 0.9596
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.0113 0.0565
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.0113 0.0565
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0113 0.0475
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.0113 0.0565
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.0113 0.0205
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0295 0.9596
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0164 0.193
Loa Loa (eye worm) hypothetical protein 0.0036 0.0295 0.0987
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.0113 0.0205
Loa Loa (eye worm) hypothetical protein 0.0039 0.0328 0.1132
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0295 0.956
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0113 0.0565
Leishmania major basic transcription factor 3a, putative 0.0037 0.0305 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.0113 0.0205
Onchocerca volvulus Protein cycle homolog 0.0039 0.0332 0.5294
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0017 0.0066 0.0825
Loa Loa (eye worm) hypothetical protein 0.0036 0.0295 0.0987
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.0113 0.0565
Mycobacterium tuberculosis Conserved protein 0.0036 0.0295 0.0341
Brugia malayi Bromodomain containing protein 0.0037 0.0309 0.1295
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0295 0.0341
Brugia malayi hypothetical protein 0.0055 0.0526 0.2205
Schistosoma mansoni coup transcription factor 0.0021 0.0113 0.0565
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0305 1
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0024 0.0148 0.0147
Leishmania major hypothetical protein, conserved 0.0036 0.0295 0.9596
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0017 0.0066 0.0326
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0305 1
Echinococcus multilocularis transcription factor btf3 0.0037 0.0305 0.0304
Echinococcus multilocularis isocitrate dehydrogenase 0.0017 0.0066 0.0065
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0295 0.148
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.0113 0.0475
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.0113 0.0565
Mycobacterium tuberculosis Conserved protein 0.0036 0.0295 0.0341
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0295 0.0341
Schistosoma mansoni hypothetical protein 0.0035 0.0282 0.1417
Loa Loa (eye worm) hypothetical protein 0.0021 0.0113 0.0205
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0164 0.0147
Loa Loa (eye worm) hypothetical protein 0.0039 0.0328 0.1132
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.0113 0.0565
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.0113 0.0565
Brugia malayi aryl hydrocarbon receptor AHR-1 0.0039 0.0328 0.1377
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0047 0.0427 0.1557
Schistosoma mansoni hypothetical protein 0.0067 0.0665 0.3344
Plasmodium falciparum nicotinamide/nicotinic acid mononucleotide adenylyltransferase 0.0582 0.6774 1
Leishmania major hypothetical protein, conserved 0.0025 0.0164 0.4592
Loa Loa (eye worm) bromodomain containing protein 0.0017 0.0072 0.0025
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0067 0.0665 0.3344
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0066 0.0822
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.0113 0.0475
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0113 0.0565
Loa Loa (eye worm) ICD-1 protein 0.0037 0.0305 0.1032
Schistosoma mansoni cpg binding protein 0.0034 0.027 0.1354
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0113 0.0475
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0017 0.0066 0.0326
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0295 0.0341
Schistosoma mansoni hypothetical protein 0.002 0.0106 0.0527
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0295 0.956
Schistosoma mansoni cpg binding protein 0.003 0.0227 0.114
Brugia malayi beta-NAC-like protein 0.0037 0.0305 0.128
Loa Loa (eye worm) hypothetical protein 0.0021 0.0113 0.0205
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.0113 0.0205
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0164 0.4592
Echinococcus granulosus FTZ F1 alpha 0.0021 0.0113 0.0565
Brugia malayi ecdysteroid receptor 0.0021 0.0113 0.0475
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0427 0.2146
Loa Loa (eye worm) hypothetical protein 0.0043 0.0379 0.1352
Loa Loa (eye worm) hypothetical protein 0.0037 0.031 0.1051
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0017 0.0066 0.0825
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.0113 0.0205
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0295 0.0341
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0427 0.0426
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0067 0.0665 0.0664
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.0113 0.0565
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.0113 0.0205
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0295 0.0341
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0113 0.0475
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.0113 0.0565
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0065 0.032
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0282 0.0281
Onchocerca volvulus 0.0036 0.0295 0.4398
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0305 1
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0065 0.032
Brugia malayi nuclear receptor NHR-88 0.0021 0.0113 0.0475
Echinococcus multilocularis thyroid hormone receptor alpha 0.0021 0.0113 0.0112
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0295 0.0341
Leishmania major protein kinase, putative 0.0017 0.0066 0.0825
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0039 0.0332 0.1146
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0113 0.0475
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.0113 0.0112
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.0113 0.0112
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0295 0.0341
Schistosoma mansoni hypothetical protein 0.0067 0.0665 0.3344
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0295 0.956
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0067 0.0665 0.3344
Brugia malayi beta-lactamase 0.0036 0.0295 0.1236
Schistosoma mansoni hypothetical protein 0.0178 0.1986 1
Echinococcus granulosus geminin 0.0178 0.1986 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0113 0.0565
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.0113 0.0112
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0017 0.0066 0.0825
Brugia malayi aryl hydrocarbon receptor nuclear translocator protein, putative 0.0039 0.0332 0.1391
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0295 0.0294
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.0113 0.0475
Brugia malayi beta-lactamase family protein 0.0036 0.0295 0.1236
Echinococcus multilocularis geminin 0.0178 0.1986 0.1985
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.0113 0.0205
Echinococcus multilocularis aryl hydrocarbon receptor 0.0056 0.0529 0.0528
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.0113 0.0475
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0113 0.0112
Mycobacterium tuberculosis Conserved protein 0.0036 0.0295 0.0341
Brugia malayi hypothetical protein 0.0025 0.0164 0.0688
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0017 0.0066 0.0822
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0017 0.0072 0.0071
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.0282 0.0281
Brugia malayi Calcitonin receptor-like protein seb-1 0.0212 0.2385 1
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.006 0.0575 0.0574
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0295 0.0341
Toxoplasma gondii ABC1 family protein 0.0036 0.0295 0.4492
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0164 0.0147
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.0113 0.0475
Loa Loa (eye worm) hypothetical protein 0.0036 0.0295 0.0987
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0024 0.0148 0.0741
Echinococcus granulosus transcription factor btf3 0.0037 0.0305 0.1533
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0066 0.0822
Schistosoma mansoni hypothetical protein 0.0067 0.0665 0.3344
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0065 0.032
Brugia malayi Isocitrate dehydrogenase 0.0017 0.0066 0.0276
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.0113 0.0475
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0017 0.0066 0.0825
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0113 0.0565
Brugia malayi isocitrate dehydrogenase 0.0017 0.0066 0.0276
Echinococcus granulosus zinc finger protein 0.0021 0.0114 0.0569
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0017 0.0072 0.0359
Schistosoma mansoni zinc finger protein 0.0015 0.0044 0.0218
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0066 0.0065
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.0113 0.0475
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0295 0.0341
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0295 0.0987
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.0113 0.0205
Loa Loa (eye worm) hypothetical protein 0.0039 0.0328 0.1132
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0017 0.0066 0.0822
Mycobacterium ulcerans bifunctional nicotinate-nucleotide adenylyltransferase NadD/hypothetical protein 0.0582 0.6774 1
Plasmodium vivax nicotinate-nucleotide adenylyltransferase, putative 0.0582 0.6774 1
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0017 0.0066 0.0825
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0212 0.2385 1
Schistosoma mansoni hypothetical protein 0.0015 0.0044 0.0218
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.0113 0.0565
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0295 0.956
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0212 0.2385 1
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0017 0.0066 0.0825
Echinococcus granulosus histone lysine methyltransferase setb 0.0017 0.0072 0.0359
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0282 0.1417
Loa Loa (eye worm) hypothetical protein 0.0021 0.0113 0.0205
Schistosoma mansoni hypothetical protein 0.0145 0.1589 0.8001
Plasmodium falciparum basic transcription factor 3b, putative 0.0037 0.0305 0.0357
Schistosoma mansoni bromodomain containing protein 0.0063 0.0617 0.3102
Loa Loa (eye worm) hypothetical protein 0.0055 0.0526 0.1983
Mycobacterium tuberculosis Probable nicotinate-nucleotide adenylyltransferase NadD (deamido-NAD(+) pyrophosphorylase) (deamido-NAD(+) diphosphorylase) (nic 0.0582 0.6774 1
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0106 0.0172
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0067 0.0665 0.0664
Echinococcus granulosus fetal alzheimer antigen falz 0.0024 0.0148 0.0741
Onchocerca volvulus 0.0055 0.0526 1
Echinococcus granulosus GPCR family 2 0.0067 0.0665 0.3344
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0064 0.063 0.3167
Treponema pallidum hypothetical protein 0.0582 0.6774 0.5
Loa Loa (eye worm) hypothetical protein 0.0021 0.0113 0.0205
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.0113 0.0112
Loa Loa (eye worm) latrophilin receptor protein 2 0.0067 0.0665 0.2582
Loa Loa (eye worm) hypothetical protein 0.0021 0.0113 0.0205
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0295 0.956
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0113 0.0565
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0017 0.0066 0.0825
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0295 0.9596
Leishmania major protein kinase, putative 0.0017 0.0066 0.0825
Brugia malayi Latrophilin receptor protein 2 0.0067 0.0665 0.2787
Mycobacterium leprae PROBABLE NICOTINATE-NUCLEOTIDE ADENYLYLTRANSFERASE NADD (DEAMIDO-NAD(+) PYROPHOSPHORYLASE) (DEAMIDO-NAD(+) DIPHOSPHORYLASE) (NIC 0.0582 0.6774 1
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0017 0.0066 0.0065
Echinococcus multilocularis cpg binding protein 0.0034 0.027 0.0269
Schistosoma mansoni aryl hydrocarbon receptor 0.0017 0.0069 0.0343
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0295 0.148
Schistosoma mansoni aryl hydrocarbon receptor nuclear translocator homolog (darnt) 0.0039 0.0332 0.1666
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0039 0.0332 0.1391
Loa Loa (eye worm) hypothetical protein 0.0039 0.0328 0.1132
Loa Loa (eye worm) hypothetical protein 0.0039 0.0337 0.1169
Brugia malayi nuclear hormone receptor 0.0021 0.0113 0.0475
Brugia malayi Bromodomain containing protein 0.0074 0.0751 0.315
Loa Loa (eye worm) hypothetical protein 0.0025 0.0164 0.0424
Schistosoma mansoni zinc finger protein 0.0021 0.0114 0.0569
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0427 0.0426
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0066 0.0822
Brugia malayi hypothetical protein 0.0039 0.0328 0.1377
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0113 0.0565
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0056 0.0529 0.1998
Schistosoma mansoni hypothetical protein 0.0067 0.0665 0.3344
Brugia malayi CXXC zinc finger family protein 0.003 0.0227 0.0953
Brugia malayi hypothetical protein 0.0039 0.0332 0.1391
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.006 0.0575 0.2894
Echinococcus granulosus aryl hydrocarbon receptor 0.0056 0.0529 0.2661
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0066 0.0065
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0164 0.0147
Loa Loa (eye worm) beta-lactamase 0.0036 0.0295 0.0987
Entamoeba histolytica hypothetical protein 0.0037 0.0305 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.0295 0.0987
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0229 0.2592 0.3766
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.0113 0.0565
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.0113 0.0565
Loa Loa (eye worm) hypothetical protein 0.0145 0.1589 0.6567
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.0113 0.0565
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0047 0.0427 0.179
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0113 0.0112
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.0113 0.0565
Onchocerca volvulus 0.0036 0.0295 0.4398
Echinococcus granulosus cpg binding protein 0.0034 0.027 0.1354
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0017 0.0069 0.0068
Echinococcus multilocularis GPCR, family 2 0.0067 0.0665 0.0664
Brugia malayi PAS domain containing protein 0.0017 0.0066 0.0276
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0017 0.0072 0.0359
Plasmodium vivax basic transcription factor 3b, putative 0.0037 0.0305 0.0357
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0427 0.2146
Brugia malayi PHD-finger family protein 0.0026 0.0175 0.0735
Schistosoma mansoni hypothetical protein 0.0178 0.1986 1
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.0282 0.1414
Loa Loa (eye worm) hypothetical protein 0.0021 0.0113 0.0205
Loa Loa (eye worm) hypothetical protein 0.0036 0.0295 0.0987
Toxoplasma gondii histone lysine methyltransferase SET1 0.006 0.0575 1
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0295 0.1236
Toxoplasma gondii NAC domain-containing protein 0.0037 0.0305 0.4698
Brugia malayi steroid hormone receptor 0.0021 0.0113 0.0475
Schistosoma mansoni cpg binding protein 0.0034 0.027 0.1354
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0017 0.0066 0.5
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0113 0.0475
Onchocerca volvulus 0.003 0.0227 0.2762
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.0113 0.0112
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0017 0.0069 0.0343
Schistosoma mansoni single-minded 0.0017 0.0066 0.0327
Schistosoma mansoni transcription factor btf3 0.0037 0.0305 0.1533
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0164 0.4592
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0113 0.0475
Mycobacterium leprae Probable lipase LipE 0.0036 0.0295 0.0341
Trichomonas vaginalis esterase, putative 0.0036 0.0295 0.956
Loa Loa (eye worm) hypothetical protein 0.0017 0.0072 0.0028
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0295 0.148
Trypanosoma cruzi transcription factor btf3, putative 0.0037 0.0305 1
Trypanosoma brucei transcription factor BTF3, putative 0.0037 0.0305 1
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0065 0.0063
Brugia malayi beta-lactamase family protein 0.0036 0.0295 0.1236
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.0113 0.0475
Loa Loa (eye worm) hypothetical protein 0.0036 0.0295 0.0987
Onchocerca volvulus 0.0036 0.0295 0.4398
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0227 0.0696
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0164 0.4592
Entamoeba histolytica transcription factor BTF3, putative 0.0037 0.0305 1
Loa Loa (eye worm) hypothetical protein 0.0067 0.0665 0.2582
Trypanosoma cruzi transcription factor btf3, putative 0.0037 0.0305 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0427 0.2146
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0113 0.0475

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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