Detailed information for compound 804527

Basic information

Technical information
  • TDR Targets ID: 804527
  • Name: 2-(4-bromophenyl)-4,4-diethyl-1,2-dihydro-3,1 -benzoxazine
  • MW: 346.262 | Formula: C18H20BrNO
  • H donors: 1 H acceptors: 0 LogP: 5.29 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCC1(CC)OC(Nc2c1cccc2)c1ccc(cc1)Br
  • InChi: 1S/C18H20BrNO/c1-3-18(4-2)15-7-5-6-8-16(15)20-17(21-18)13-9-11-14(19)12-10-13/h5-12,17,20H,3-4H2,1-2H3
  • InChiKey: NRZIZNDPQGHLJT-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • Oprea1_175896

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni cpg binding protein 0.0032 0.0144 0.0193
Loa Loa (eye worm) major facilitator superfamily transporter 0.0031 0.0125 0.0255
Echinococcus granulosus g-protein coupled receptor 0.0048 0.0318 0.0404
Loa Loa (eye worm) hypothetical protein 0.0048 0.0318 0.0651
Entamoeba histolytica phosphofructokinase, putative 0.0109 0.099 0.3275
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0049 0.0357
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0024 0.0054 0.0069
Schistosoma mansoni opsin-like receptor 0.0048 0.0318 0.0428
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0042 0.0246 0.0505
Echinococcus multilocularis neuropeptide receptor A26 0.0048 0.0318 0.0404
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0125 0.0412
Loa Loa (eye worm) jmjC domain-containing protein 0.0459 0.4879 1
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0112 0.0067
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0125 0.0412
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0067 0.0524 0.0731
Loa Loa (eye worm) hypothetical protein 0.0053 0.0373 0.0764
Echinococcus granulosus solute carrier family 22 0.0031 0.0125 0.0158
Echinococcus granulosus neuropeptides capa receptor 0.0048 0.0318 0.0404
Loa Loa (eye worm) sugar transporter 0.0031 0.0125 0.0255
Echinococcus multilocularis G protein coupled receptor 139 0.0048 0.0318 0.0404
Echinococcus granulosus PHD finger protein rhinoceros 0.0222 0.2253 0.2864
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0048 0.0318 0.0428
Schistosoma mansoni serine/threonine protein kinase 0.0066 0.0523 0.0704
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0125 0.0412
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.3024 1
Plasmodium falciparum calcium-dependent protein kinase 2 0.0067 0.0524 0.048
Trypanosoma brucei glucose transporter, putative 0.0067 0.0533 0.5378
Onchocerca volvulus 0.0048 0.0318 0.0579
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0104 0.0214
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0048 0.0323 0.2103
Echinococcus multilocularis JmjC domain containing protein 4 0.0072 0.0582 0.0741
Onchocerca volvulus 0.0048 0.0318 0.0579
Echinococcus multilocularis fmrfamide receptor 0.0048 0.0318 0.0404
Brugia malayi hypothetical protein 0.0122 0.1143 0.1454
Brugia malayi Major Facilitator Superfamily protein 0.0031 0.0125 0.0158
Echinococcus granulosus General substrate transporter 0.0187 0.1854 0.2358
Echinococcus granulosus allatostatin A receptor 0.0048 0.0318 0.0404
Plasmodium vivax hypothetical protein, conserved 0.0222 0.2253 0.2218
Loa Loa (eye worm) hypothetical protein 0.0048 0.0318 0.0651
Schistosoma mansoni cpg binding protein 0.0032 0.0144 0.0193
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0065 0.0508 0.0684
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0048 0.0318 0.0428
Loa Loa (eye worm) hypothetical protein 0.0048 0.0318 0.0651
Brugia malayi hypothetical protein 0.0048 0.0318 0.0404
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0066 0.0523 0.0665
Echinococcus granulosus microtubule associated protein 2 0.0689 0.743 0.9447
Loa Loa (eye worm) major facilitator superfamily transporter 0.0031 0.0125 0.0255
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0049 0.0162
Loa Loa (eye worm) hypothetical protein 0.0048 0.0318 0.0651
Echinococcus multilocularis neuropeptides capa receptor 0.0048 0.0318 0.0404
Loa Loa (eye worm) hypothetical protein 0.0048 0.0318 0.0651
Onchocerca volvulus Putative transporter 0.0031 0.0125 0.0163
Echinococcus granulosus JmjC domain containing protein 4 0.0072 0.0582 0.0741
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0067 0.0524 0.0731
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.3024 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0049 0.01
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0076 0.0628 0.6341
Loa Loa (eye worm) glutamate receptor 0.0162 0.1581 0.3241
Schistosoma mansoni biogenic amine (5HT) receptor 0.0048 0.0318 0.0428
Entamoeba histolytica protein kinase, putative 0.0066 0.0523 0.173
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.3024 1
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0031 0.0125 0.0911
Onchocerca volvulus 0.0048 0.0318 0.0579
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0049 0.0493
Trypanosoma brucei glucose transporter, putative 0.0067 0.0533 0.5378
Loa Loa (eye worm) hypothetical protein 0.0122 0.1143 0.2343
Brugia malayi 6-phosphofructokinase 0.0109 0.099 0.1259
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0143 0.1368 1
Onchocerca volvulus 0.0031 0.0125 0.0163
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0125 0.0412
Echinococcus granulosus serotonin receptor 0.0048 0.0318 0.0404
Toxoplasma gondii sugar transporter ST2 0.0031 0.0125 0.0121
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0048 0.0318 0.0404
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0125 0.0412
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0031 0.0125 0.008
Brugia malayi F/Y-rich N-terminus family protein 0.0083 0.0711 0.0904
Brugia malayi RE15519p 0.0048 0.0318 0.0404
Brugia malayi Serotonin receptor 0.0048 0.0318 0.0404
Echinococcus granulosus rhodopsin orphan GPCR 0.0048 0.0318 0.0404
Mycobacterium ulcerans hypothetical protein 0.0024 0.0049 0.0357
Brugia malayi hypothetical protein 0.0048 0.0318 0.0404
Trypanosoma brucei glucose transporter, putative 0.0067 0.0533 0.5378
Schistosoma mansoni hypothetical protein 0.0048 0.0318 0.0428
Loa Loa (eye worm) hypothetical protein 0.0048 0.0318 0.0651
Loa Loa (eye worm) hypothetical protein 0.0048 0.0318 0.0651
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0125 0.0412
Schistosoma mansoni metabotropic glutamate receptor 0.0136 0.129 0.1736
Brugia malayi phosphofructokinase 0.0109 0.099 0.1259
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0125 0.0412
Schistosoma mansoni 6-phosphofructokinase 0.0109 0.099 0.1333
Trypanosoma brucei glucose transporter, putative 0.0067 0.0533 0.5378
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0048 0.0318 0.0404
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0125 0.0412
Schistosoma mansoni opsin-like receptor 0.0048 0.0318 0.0428
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0048 0.0318 0.0404
Loa Loa (eye worm) hypothetical protein 0.0048 0.0318 0.0651
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0015 0.003
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0048 0.0318 0.0404
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0125 0.0412
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0222 0.2253 0.3032
Schistosoma mansoni glucose transport protein 0.0217 0.2193 0.2951
Onchocerca volvulus 0.0029 0.0104 0.012
Echinococcus multilocularis serotonin receptor 0.0048 0.0318 0.0404
Brugia malayi putative neuropeptide receptor 0.0048 0.0318 0.0404
Trypanosoma cruzi hexose transporter, putative 0.0067 0.0533 0.5378
Echinococcus granulosus somatostatin receptor 0.0048 0.0318 0.0404
Loa Loa (eye worm) hypothetical protein 0.0072 0.0582 0.1194
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0048 0.0318 0.0404
Onchocerca volvulus 0.0048 0.0318 0.0579
Onchocerca volvulus 0.0031 0.0125 0.0163
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.3024 1
Loa Loa (eye worm) hypothetical protein 0.005 0.0338 0.0694
Loa Loa (eye worm) sugar transporter 0.0217 0.2193 0.4494
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.3024 1
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0125 0.0412
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0049 0.0357
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.0045 0.0457
Echinococcus multilocularis neuropeptide receptor 0.0048 0.0318 0.0404
Trichomonas vaginalis glucose transporter, putative 0.0067 0.0533 0.1761
Toxoplasma gondii PHD-finger domain-containing protein 0.0073 0.0592 0.0837
Schistosoma mansoni hypothetical protein 0.0026 0.0078 0.0104
Plasmodium falciparum mitogen-activated protein kinase 2 0.0351 0.3675 0.3646
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0125 0.0412
Onchocerca volvulus 0.0031 0.0125 0.0163
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0029 0.0112 0.0369
Echinococcus multilocularis L aminoadipate semialdehyde 0.0083 0.0707 0.0899
Brugia malayi Tachykinin-like peptides receptor 99D 0.0048 0.0318 0.0404
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0048 0.0318 0.0428
Trichomonas vaginalis sugar transport protein, putative 0.0031 0.0125 0.0412
Loa Loa (eye worm) jmjC domain-containing protein 0.0072 0.0582 0.1194
Echinococcus multilocularis solute carrier family 22 0.0031 0.0125 0.0158
Brugia malayi G-protein coupled receptor 0.0048 0.0318 0.0404
Echinococcus granulosus g protein coupled receptor 0.0048 0.0318 0.0404
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0125 0.0412
Onchocerca volvulus Poor gastrulation protein homolog 0.0026 0.0078 0.0062
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0072 0.0582 0.5882
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.005 0.0338 0.043
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0125 0.0412
Echinococcus multilocularis rhodopsin orphan GPCR 0.0048 0.0318 0.0404
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0049 0.0493
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0029 0.0112 0.0369
Echinococcus multilocularis neuropeptide Y receptor 0.0048 0.0318 0.0404
Brugia malayi ORL1-like opioid receptor 0.0048 0.0318 0.0404
Plasmodium vivax lysine--tRNA ligase, putative 0.0048 0.0323 0.0279
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0112 0.0067
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0125 0.0412
Brugia malayi major facilitator superfamily protein 0.0031 0.0125 0.0158
Giardia lamblia Hexose transporter 0.0031 0.0125 0.0412
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0729 0.7865 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0125 0.0255
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0065 0.0508 0.3501
Echinococcus granulosus biogenic amine 5HT receptor 0.0048 0.0318 0.0404
Trypanosoma brucei glucose transporter 1E 0.0067 0.0533 0.5378
Toxoplasma gondii 6-phosphofructokinase 0.0029 0.0112 0.0101
Brugia malayi putative neuropeptide receptor NPR1 0.0048 0.0318 0.0404
Schistosoma mansoni jumonji/arid domain-containing protein 0.0273 0.2811 0.3784
Loa Loa (eye worm) hypothetical protein 0.0038 0.0211 0.0433
Echinococcus granulosus rhodopsin orphan GPCR 0.0048 0.0318 0.0404
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0067 0.0524 0.048
Onchocerca volvulus 0.0031 0.0125 0.0163
Toxoplasma gondii sugar transporter ST3 0.0031 0.0125 0.0121
Schistosoma mansoni amine GPCR 0.0048 0.0318 0.0428
Brugia malayi GnHR receptor homolog 0.0048 0.0318 0.0404
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0125 0.0412
Loa Loa (eye worm) TYRA-2 protein 0.0048 0.0318 0.0651
Brugia malayi AF-10 protein 0.0073 0.0592 0.0753
Chlamydia trachomatis lysine--tRNA ligase 0.0048 0.0323 1
Schistosoma mansoni hypothetical protein 0.0409 0.4317 0.581
Loa Loa (eye worm) jmjC domain-containing protein 0.0273 0.2811 0.5761
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0147 0.1413 0.1796
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0048 0.0318 0.0651
Brugia malayi hypothetical protein 0.0031 0.0125 0.0158
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0164 0.0208
Echinococcus multilocularis zinc finger protein 0.0021 0.0021 0.0027
Brugia malayi larval opioid receptor 0.0048 0.0318 0.0404
Giardia lamblia Lysyl-tRNA synthetase 0.0048 0.0323 0.107
Onchocerca volvulus Huntingtin homolog 0.0122 0.1143 0.2357
Brugia malayi major facilitator superfamily protein 0.0031 0.0125 0.0158
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0049 0.0027
Echinococcus multilocularis sex peptide receptor 0.0048 0.0318 0.0404
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0048 0.0318 0.0428
Loa Loa (eye worm) hypothetical protein 0.0024 0.0049 0.01
Trypanosoma brucei THT1 - hexose transporter, putative 0.0067 0.0533 0.5378
Echinococcus multilocularis g protein coupled receptor 0.0048 0.0318 0.0404
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0048 0.0318 0.0428
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0076 0.0628 0.6341
Echinococcus granulosus GPCR family 3 C terminal 0.0026 0.0078 0.0099
Schistosoma mansoni hypothetical protein 0.0048 0.0318 0.0428
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0292 0.3024 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0048 0.0318 0.0404
Echinococcus multilocularis rhodopsin orphan GPCR 0.0048 0.0318 0.0404
Schistosoma mansoni hypothetical protein 0.0021 0.0015 0.002
Schistosoma mansoni metabotropic glutamate receptor 0.0079 0.0661 0.089
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0112 0.249
Loa Loa (eye worm) hypothetical protein 0.0024 0.0049 0.01
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0083 0.0707 0.0952
Loa Loa (eye worm) hypothetical protein 0.0048 0.0323 0.0663
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0048 0.0318 0.0404
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0048 0.0318 0.0428
Schistosoma mansoni neuropeptide receptor 0.0048 0.0318 0.0428
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0083 0.0707 0.0899
Onchocerca volvulus 0.0031 0.0125 0.0163
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.3024 1
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0066 0.0523 0.0665
Onchocerca volvulus 0.0048 0.0318 0.0579
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0065 0.0508 0.0646
Echinococcus multilocularis lysine specific demethylase 5A 0.0269 0.2772 0.3524
Trypanosoma cruzi hexose transporter 0.0067 0.0533 0.5378
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0217 0.2193 0.2788
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0045 0.0457
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0109 0.099 0.7146
Plasmodium vivax JmjC domain containing protein 0.0072 0.0582 0.054
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0072 0.0582 0.0784
Loa Loa (eye worm) G-protein coupled receptor 0.0048 0.0318 0.0651
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0061 0.0466 0.0592
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0066 0.0523 0.0665
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0184 0.1827 0.246
Schistosoma mansoni amine GPCR 0.0048 0.0318 0.0428
Echinococcus multilocularis PHD finger protein rhinoceros 0.0222 0.2253 0.2864
Loa Loa (eye worm) hypothetical protein 0.0031 0.0125 0.0255
Echinococcus multilocularis serotonin receptor 0.0048 0.0318 0.0404
Echinococcus multilocularis jumonji domain containing protein 0.031 0.3219 0.4093
Loa Loa (eye worm) hypothetical protein 0.0048 0.0318 0.0651
Echinococcus granulosus solute carrier family 22 0.0031 0.0125 0.0158
Echinococcus granulosus hypothetical protein 0.0048 0.0318 0.0404
Entamoeba histolytica hypothetical protein 0.0023 0.0045 0.015
Entamoeba histolytica protein kinase, putative 0.0066 0.0523 0.173
Giardia lamblia PHD finger protein 15 0.0222 0.2253 0.7451
Brugia malayi jmjC domain containing protein 0.0072 0.0582 0.0741
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0048 0.0318 0.0428
Loa Loa (eye worm) hypothetical protein 0.0031 0.0125 0.0255
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0065 0.0508 0.0646
Plasmodium falciparum phd finger protein, putative 0.0222 0.2253 0.2218
Loa Loa (eye worm) hypothetical protein 0.0031 0.0125 0.0255
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0049 0.0357
Brugia malayi Receptor family ligand binding region containing protein 0.0042 0.0246 0.0313
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0048 0.0318 0.0428
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0048 0.0318 0.0651
Brugia malayi hypothetical protein 0.0048 0.0318 0.0404
Echinococcus multilocularis jumonji domain containing 1A 0.0072 0.0582 0.0741
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0125 0.0412
Echinococcus multilocularis rhodopsin orphan GPCR 0.0048 0.0318 0.0404
Brugia malayi G-protein coupled receptor 0.0048 0.0318 0.0404
Trypanosoma cruzi hexose transporter, putative 0.0031 0.0125 0.1258
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0024 0.0054 0.0073
Echinococcus granulosus Sugar transporter ERD6 protein 0.0031 0.0125 0.0158
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0112 0.0067
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0065 0.0508 0.0684
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0112 0.249
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0066 0.0523 0.0665
Echinococcus multilocularis solute carrier family 22 0.0031 0.0125 0.0158
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0048 0.0318 0.0404
Brugia malayi hypothetical protein 0.0048 0.0318 0.0404
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0031 0.0125 1
Echinococcus multilocularis lysyl tRNA synthetase 0.0048 0.0323 0.0411
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0048 0.0318 0.0404
Echinococcus granulosus neuropeptide receptor A26 0.0048 0.0318 0.0404
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0125 0.0412
Onchocerca volvulus 0.0048 0.0318 0.0579
Brugia malayi 6-phosphofructokinase 0.0109 0.099 0.1259
Brugia malayi Melatonin receptor type 1A 0.0048 0.0318 0.0404
Echinococcus multilocularis lysine specific demethylase 6a 0.0072 0.0582 0.0741
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0048 0.0318 0.0428
Schistosoma mansoni neuropeptide F-like receptor 0.0048 0.0318 0.0428
Leishmania major glucose transporter, lmgt2 0.0067 0.0533 0.5378
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0048 0.0323 0.3266
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0049 0.0027
Loa Loa (eye worm) hypothetical protein 0.0048 0.0318 0.0651
Onchocerca volvulus 0.0048 0.0318 0.0579
Echinococcus granulosus solute carrier family 22 0.0031 0.0125 0.0158
Onchocerca volvulus 0.0031 0.0125 0.0163
Echinococcus granulosus lysine specific demethylase 6a 0.0072 0.0582 0.0741
Echinococcus multilocularis General substrate transporter 0.0187 0.1854 0.2358
Echinococcus granulosus dnaJ subfamily B 0.0409 0.4317 0.5489
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0048 0.0318 0.0428
Loa Loa (eye worm) hypothetical protein 0.0065 0.0508 0.1042
Plasmodium falciparum JmjC domain-containing protein, putative 0.0072 0.0582 0.054
Loa Loa (eye worm) glutamate receptor 0.0064 0.0492 0.1009
Plasmodium vivax hexose transporter 0.0217 0.2193 0.2157
Onchocerca volvulus 0.0048 0.0318 0.0579
Loa Loa (eye worm) hypothetical protein 0.0072 0.0582 0.1194
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0109 0.099 0.3182
Loa Loa (eye worm) runx1 0.0056 0.0402 0.0823
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0048 0.0318 0.0428
Onchocerca volvulus 0.0031 0.0125 0.0163
Plasmodium falciparum calcium-dependent protein kinase 4 0.0067 0.0524 0.048
Brugia malayi hypothetical protein 0.0048 0.0318 0.0404
Trypanosoma brucei glucose transporter 2A 0.0067 0.0533 0.5378
Schistosoma mansoni jumonji/arid domain-containing protein 0.0273 0.2811 0.3784
Trypanosoma brucei glucose transporter, putative 0.0067 0.0533 0.5378
Echinococcus multilocularis calcium dependent protein kinase 0.0062 0.0478 0.0607
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0049 0.0162
Toxoplasma gondii phosphofructokinase PFKII 0.0029 0.0112 0.0101
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0061 0.0466 0.0592
Loa Loa (eye worm) hypothetical protein 0.0048 0.0318 0.0651
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0729 0.7865 1
Toxoplasma gondii protein kinase, putative 0.0613 0.6585 1
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0112 0.0369
Loa Loa (eye worm) PHD-finger family protein 0.0222 0.2253 0.4617
Onchocerca volvulus Alhambra homolog 0.0222 0.2253 0.4746
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0048 0.0318 0.0428
Schistosoma mansoni hypothetical protein 0.0222 0.2253 0.3032
Loa Loa (eye worm) hypothetical protein 0.0048 0.0318 0.0651
Plasmodium falciparum calcium-dependent protein kinase 1 0.0067 0.0524 0.048
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0217 0.2193 0.2788
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0027 0.0083 0.0169
Trichomonas vaginalis phosphofructokinase, putative 0.0109 0.099 0.3275
Schistosoma mansoni hypothetical protein 0.0048 0.0318 0.0428
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0125 0.0412
Brugia malayi Sugar transporter family protein 0.0031 0.0125 0.0158
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0125 0.0412
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0076 0.0628 0.6341
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0125 0.0412
Brugia malayi lysyl-tRNA synthetase 0.0048 0.0323 0.0411
Echinococcus granulosus rhodopsin orphan GPCR 0.0048 0.0318 0.0404
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0048 0.0323 0.2365
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0076 0.0628 0.6341
Echinococcus granulosus neuropeptide Y receptor 0.0048 0.0318 0.0404
Trypanosoma brucei glucose transporter, putative 0.0067 0.0533 0.5378
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0217 0.2193 0.2788
Loa Loa (eye worm) hypothetical protein 0.0066 0.0523 0.1072
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0112 0.0369
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0042 0.0257 0.0851
Schistosoma mansoni histamine h1 receptor 0.0048 0.0318 0.0428
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0048 0.0318 0.0404
Echinococcus granulosus lysyl tRNA synthetase 0.0048 0.0323 0.0411
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0023 0.0041 0.0302
Loa Loa (eye worm) jmjC domain-containing protein 0.0072 0.0582 0.1194
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0048 0.0318 0.0404
Schistosoma mansoni adenoreceptor 0.0048 0.0318 0.0428
Loa Loa (eye worm) hypothetical protein 0.0041 0.0237 0.0487
Schistosoma mansoni biogenic amine (5HT) receptor 0.0048 0.0318 0.0428
Trichomonas vaginalis conserved hypothetical protein 0.0217 0.2193 0.7252
Schistosoma mansoni phosphatidylserine receptor 0.0072 0.0582 0.0784
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0066 0.0523 0.0665
Loa Loa (eye worm) hypothetical protein 0.0031 0.0125 0.0255
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0217 0.2193 0.2788
Schistosoma mansoni amine GPCR 0.0048 0.0318 0.0428
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.0533 0.1761
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0048 0.0323 0.3266
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.0045 0.0331
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0125 0.0412
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0125 0.0412
Trypanosoma cruzi glucose transporter, putative 0.0031 0.0125 0.1258
Giardia lamblia Prolyl-tRNA synthetase 0.0065 0.0508 0.1681
Brugia malayi CXXC zinc finger family protein 0.0029 0.0104 0.0133
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0048 0.0318 0.0428
Loa Loa (eye worm) hypothetical protein 0.0031 0.0125 0.0255
Echinococcus multilocularis microtubule associated protein 2 0.0689 0.743 0.9447
Echinococcus multilocularis peregrin 0.0225 0.2279 0.2898
Echinococcus multilocularis G-protein coupled receptor, putative 0.0048 0.0318 0.0404
Schistosoma mansoni neuropeptide F-like receptor 0.0048 0.0318 0.0428
Loa Loa (eye worm) hypothetical protein 0.0031 0.0125 0.0255
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0048 0.0318 0.0404
Onchocerca volvulus 0.0048 0.0318 0.0579
Toxoplasma gondii PHD-finger domain-containing protein 0.0222 0.2253 0.3375
Schistosoma mansoni phd/f-box containing protein 0.0072 0.0582 0.0784
Trichomonas vaginalis phosphofructokinase, putative 0.0109 0.099 0.3275
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0048 0.0323 0.107
Onchocerca volvulus 0.0048 0.0318 0.0579
Brugia malayi Major Facilitator Superfamily protein 0.0031 0.0125 0.0158
Onchocerca volvulus Neuropeptide F receptor homolog 0.0048 0.0318 0.0579
Brugia malayi hypothetical protein 0.0031 0.0125 0.0158
Brugia malayi Calcitonin receptor-like protein seb-1 0.005 0.0338 0.043
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0125 0.0412
Echinococcus multilocularis phd:f box containing protein 0.0072 0.0582 0.0741
Brugia malayi Cam kinase protein 1 0.0066 0.0523 0.0665
Brugia malayi hypothetical protein 0.0048 0.0318 0.0404
Echinococcus granulosus zinc finger protein 0.0021 0.0021 0.0027
Loa Loa (eye worm) hypothetical protein 0.0048 0.0318 0.0651
Echinococcus granulosus tm gpcr rhodopsin 0.0048 0.0318 0.0404
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0075 0.0622 0.079
Trichomonas vaginalis CAMK family protein kinase 0.0066 0.0523 0.173
Giardia lamblia Fructose-bisphosphate aldolase 0.0292 0.3024 1
Leishmania major myo-inositol/proton symporter (MIT) 0.0031 0.0125 0.1258
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0143 0.1368 1
Loa Loa (eye worm) hypothetical protein 0.0048 0.0318 0.0651
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0217 0.2193 0.2788
Echinococcus multilocularis allatostatin A receptor 0.0048 0.0318 0.0404
Echinococcus granulosus jumonji domain containing protein 0.031 0.3219 0.4093
Trichomonas vaginalis phosphofructokinase, putative 0.0109 0.099 0.3275
Echinococcus multilocularis cpg binding protein 0.0032 0.0144 0.0183
Trypanosoma brucei sugar transporter, putative 0.0031 0.0125 0.1258
Loa Loa (eye worm) hypothetical protein 0.0031 0.0125 0.0255
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0125 0.0412
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0029 0.0112 0.0236
Loa Loa (eye worm) hypothetical protein 0.0048 0.0318 0.0651
Echinococcus multilocularis 6 phosphofructokinase 0.0109 0.099 0.1259
Echinococcus granulosus 7TM GPCR rhodopsin 0.0048 0.0318 0.0404
Echinococcus multilocularis rhodopsin orphan GPCR 0.0048 0.0318 0.0404
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0048 0.0318 0.0428
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0109 0.099 1
Onchocerca volvulus 0.0031 0.0125 0.0163
Schistosoma mansoni glucose transport protein 0.0217 0.2193 0.2951
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.3024 1
Onchocerca volvulus 0.0031 0.0125 0.0163
Schistosoma mansoni mixed-lineage leukemia protein mll 0.008 0.0671 0.0904
Schistosoma mansoni hypothetical protein 0.0048 0.0318 0.0428
Loa Loa (eye worm) hypothetical protein 0.0048 0.0318 0.0651
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0125 0.0412
Schistosoma mansoni protein kinase 0.0066 0.0523 0.0704
Echinococcus multilocularis g protein coupled receptor 0.0048 0.0318 0.0404
Schistosoma mansoni neuropeptide receptor 0.0048 0.0318 0.0428
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.0461 0.062
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0065 0.0508 0.0646
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0067 0.0524 0.048
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.3024 1
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0031 0.0125 0.0911
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0048 0.0318 0.0651
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0048 0.0318 0.0404
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0066 0.0523 0.5283
Brugia malayi hypothetical protein 0.0443 0.4692 0.5966
Loa Loa (eye worm) hypothetical protein 0.0048 0.0318 0.0651
Brugia malayi jmjC domain containing protein 0.0072 0.0582 0.0741
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.0045 0.0331
Plasmodium vivax CDK-related protein kinase 6, putative 0.0921 1 1
Schistosoma mansoni neuropeptide f receptor 76f 0.0048 0.0318 0.0428
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0072 0.0582 0.0821
Echinococcus multilocularis dnaJ subfamily B 0.0409 0.4317 0.5489
Echinococcus multilocularis synaptic vesicle 2 protein 0.0031 0.0125 0.0158
Echinococcus multilocularis neuropeptides capa receptor 0.0048 0.0318 0.0404
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0049 0.0357
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0048 0.0318 0.0404
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0048 0.0318 0.0428
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0066 0.0523 0.0665
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0112 0.0369
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0125 0.0412
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0029 0.0112 0.0369
Echinococcus granulosus fetal alzheimer antigen falz 0.0024 0.0054 0.0069
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0199 0.1996 0.2538
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0048 0.0318 0.0404
Echinococcus multilocularis neuropeptide s receptor 0.0048 0.0318 0.0404
Brugia malayi PHD-finger family protein 0.0027 0.008 0.0102
Echinococcus granulosus sex peptide receptor 0.0048 0.0318 0.0404
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0125 0.0412
Brugia malayi hypothetical protein 0.0048 0.0318 0.0404
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0074 0.0612 0.0569
Leishmania major protein kinase, putative 0.0066 0.0523 0.5283
Trypanosoma brucei THT1 - hexose transporter, putative 0.0067 0.0533 0.5378
Loa Loa (eye worm) hypothetical protein 0.0048 0.0318 0.0651
Onchocerca volvulus 0.0048 0.0318 0.0579
Loa Loa (eye worm) jmjC domain-containing protein 0.0072 0.0582 0.1194
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0048 0.0318 0.0404
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0048 0.0318 0.0428
Schistosoma mansoni biogenic amine receptor 0.0048 0.0318 0.0428
Onchocerca volvulus 0.0031 0.0125 0.0163
Echinococcus granulosus biogenic amine 5HT receptor 0.0048 0.0318 0.0404
Trypanosoma cruzi hexose transporter, putative 0.0067 0.0533 0.5378
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0072 0.0582 0.0821
Toxoplasma gondii transporter, major facilitator family protein 0.0031 0.0125 0.0121
Onchocerca volvulus 0.0048 0.0318 0.0579
Loa Loa (eye worm) hypothetical protein 0.0031 0.0125 0.0255
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.0533 0.1761
Loa Loa (eye worm) hypothetical protein 0.0031 0.0125 0.0255
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0125 0.0412
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0048 0.0318 0.0404
Onchocerca volvulus 0.0031 0.0125 0.0163
Echinococcus granulosus metabotropic glutamate receptor 2 0.0136 0.129 0.164
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0041 0.0242 0.1773
Brugia malayi jmjC domain containing protein 0.0072 0.0582 0.0741
Loa Loa (eye worm) hypothetical protein 0.0048 0.0318 0.0651
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0112 0.0369
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0049 0.0162
Loa Loa (eye worm) hypothetical protein 0.0122 0.1143 0.2343
Trichomonas vaginalis sugar transporter, putative 0.0067 0.0533 0.1761
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0112 0.0369
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0125 0.0412
Onchocerca volvulus 0.0031 0.0125 0.0163
Toxoplasma gondii facilitative glucose transporter GT1 0.0217 0.2193 0.3284
Brugia malayi Dopamine receptor protein 1 0.0048 0.0318 0.0404
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0066 0.0523 0.1072
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0072 0.0582 0.5882
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0125 0.0412
Echinococcus multilocularis neuropeptide receptor 0.0048 0.0318 0.0404
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0066 0.0523 0.1072
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0049 0.0357
Loa Loa (eye worm) hypothetical protein 0.0048 0.0318 0.0651
Loa Loa (eye worm) hypothetical protein 0.0076 0.0632 0.1295
Brugia malayi AKH receptor 0.0048 0.0318 0.0404
Schistosoma mansoni sugar transporter 0.0031 0.0125 0.0168
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0125 0.0412
Leishmania major hypothetical protein, conserved 0.0072 0.0582 0.5882
Toxoplasma gondii PHD-finger domain-containing protein 0.0222 0.2253 0.3375
Onchocerca volvulus 0.0031 0.0125 0.0163
Loa Loa (eye worm) melatonin receptor type 1A 0.0048 0.0318 0.0651
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0073 0.0592 0.0837
Trypanosoma brucei THT1 - hexose transporter, putative 0.0067 0.0533 0.5378
Trypanosoma brucei glucose transporter, putative 0.0067 0.0533 0.5378
Schistosoma mansoni jumonji domain containing protein 0.0579 0.6204 0.8351
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0031 0.0125 0.0911
Onchocerca volvulus Metabotropic glutamate receptor homolog 0.0026 0.0078 0.0062
Echinococcus granulosus jumonji domain containing 1A 0.0072 0.0582 0.0741
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0026 0.0078 0.0099
Trichomonas vaginalis sugar transporter, putative 0.0067 0.0533 0.1761
Schistosoma mansoni microtubule-associated protein tau 0.0689 0.743 1
Entamoeba histolytica hypothetical protein 0.0048 0.0323 0.107
Onchocerca volvulus Huntingtin homolog 0.0122 0.1143 0.2357
Loa Loa (eye worm) hypothetical protein 0.0048 0.0318 0.0651
Schistosoma mansoni neuropeptide receptor 0.0048 0.0318 0.0428
Echinococcus granulosus rhodopsin orphan GPCR 0.0048 0.0318 0.0404
Loa Loa (eye worm) hypothetical protein 0.0048 0.0318 0.0651
Echinococcus multilocularis neuropeptide FF receptor 2 0.0048 0.0318 0.0404
Schistosoma mansoni biogenic amine receptor 0.0048 0.0318 0.0428
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0031 0.0125 0.1258
Loa Loa (eye worm) hypothetical protein 0.0048 0.0318 0.0651
Trichomonas vaginalis sugar transporter, putative 0.0067 0.0533 0.1761
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0048 0.0318 0.0404
Plasmodium vivax calcium-dependent protein kinase, putative 0.0067 0.0524 0.048
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0048 0.0318 0.0404
Brugia malayi metabotropic glutamate receptor type 2 0.0079 0.0661 0.0841
Plasmodium falciparum hexose transporter 0.0217 0.2193 0.2157
Brugia malayi Dopamine receptor 0.0048 0.0318 0.0404
Loa Loa (eye worm) hypothetical protein 0.0048 0.0318 0.0651
Mycobacterium ulcerans integral membrane transport protein 0.0031 0.0125 0.0911
Onchocerca volvulus 0.0031 0.0125 0.0163
Loa Loa (eye worm) hypothetical protein 0.0031 0.0125 0.0255
Echinococcus multilocularis neuropeptide Y receptor 0.0048 0.0318 0.0404
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0125 0.0412
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0125 0.0412
Brugia malayi hypothetical protein 0.0048 0.0318 0.0404
Toxoplasma gondii sugar transporter ST1 0.0031 0.0125 0.0121
Brugia malayi G protein-coupled receptor 0.0048 0.0318 0.0404
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0125 0.0412
Echinococcus multilocularis g-protein coupled receptor 0.0048 0.0318 0.0404
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.0045 0.0331
Loa Loa (eye worm) hypothetical protein 0.0048 0.0318 0.0651
Loa Loa (eye worm) hypothetical protein 0.0031 0.0125 0.0255
Brugia malayi Metabotropic glutamate receptor precursor. 0.0162 0.1581 0.2011
Plasmodium vivax hypothetical protein, conserved 0.0074 0.0612 0.0569
Schistosoma mansoni lysyl-tRNA synthetase 0.0048 0.0323 0.0435
Echinococcus granulosus G protein coupled receptor 139 0.0048 0.0318 0.0404
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0041 0.0242 0.1773
Echinococcus granulosus neuropeptide s receptor 0.0048 0.0318 0.0404
Trichomonas vaginalis glucose transporter, putative 0.0031 0.0125 0.0412
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0125 0.0412
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0049 0.0062
Loa Loa (eye worm) hypothetical protein 0.0199 0.1996 0.4091
Schistosoma mansoni growth hormone secretagogue receptor 0.0048 0.0318 0.0428
Echinococcus multilocularis fmrfamide receptor 0.0048 0.0318 0.0404
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0048 0.0318 0.0651
Brugia malayi hypothetical protein 0.0048 0.0318 0.0404
Giardia lamblia Sugar-proton symporter 0.0031 0.0125 0.0412
Loa Loa (eye worm) hypothetical protein 0.0048 0.0318 0.0651
Loa Loa (eye worm) neuropeptide F receptor 0.0048 0.0318 0.0651
Loa Loa (eye worm) hypothetical protein 0.0031 0.0125 0.0255
Brugia malayi Serotonin receptor 0.0048 0.0318 0.0404
Trichomonas vaginalis myo-inositol transporter, putative 0.0031 0.0125 0.0412
Brugia malayi hypothetical protein 0.0031 0.0125 0.0158
Loa Loa (eye worm) hypothetical protein 0.0222 0.2253 0.4617
Plasmodium falciparum calcium-dependent protein kinase 5 0.0067 0.0524 0.048
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0048 0.0318 0.0404
Brugia malayi jmjC domain containing protein 0.0729 0.7865 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0049 0.0357
Echinococcus multilocularis rhodopsin orphan GPCR 0.0048 0.0318 0.0404
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0217 0.2193 0.2788
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0072 0.0582 0.5882
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0048 0.0318 0.0428
Brugia malayi Sugar transporter family protein 0.0031 0.0125 0.0158
Brugia malayi PHD-finger family protein 0.0076 0.0632 0.0803
Toxoplasma gondii lysine-tRNA ligase 0.0048 0.0323 0.0425
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0065 0.0508 0.1681
Schistosoma mansoni lozenge 0.0056 0.0402 0.0541
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0292 0.3024 1
Loa Loa (eye worm) hypothetical protein 0.0048 0.0318 0.0651
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0125 0.0412
Schistosoma mansoni hypothetical protein 0.0034 0.0164 0.022
Echinococcus granulosus phd:f box containing protein 0.0072 0.0582 0.0741
Loa Loa (eye worm) hypothetical protein 0.0048 0.0318 0.0651
Schistosoma mansoni protein phosphatase 2C 0.0072 0.0582 0.0784
Brugia malayi sulfakinin receptor protein 0.0048 0.0318 0.0404
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0112 0.0067
Plasmodium vivax sugar transporter, putative 0.0031 0.0125 0.008
Echinococcus granulosus lysine specific demethylase 5A 0.0273 0.2811 0.3574
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0217 0.2193 0.2788
Schistosoma mansoni sugar transporter 0.0031 0.0125 0.0168
Schistosoma mansoni amine GPCR 0.0048 0.0318 0.0428
Echinococcus granulosus neuropeptide receptor 0.0048 0.0318 0.0404
Onchocerca volvulus 0.0083 0.0707 0.1418
Loa Loa (eye worm) pigment dispersing factor receptor c 0.005 0.0338 0.0694
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0125 0.0412
Loa Loa (eye worm) hypothetical protein 0.0048 0.0318 0.0651
Loa Loa (eye worm) hypothetical protein 0.0048 0.0318 0.0651
Echinococcus multilocularis Protein lozenge 0.0056 0.0402 0.0511
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0066 0.0523 0.0665
Schistosoma mansoni myosin xvIII 0.0048 0.0318 0.0428
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0036 0.0184 0.0234
Schistosoma mansoni sugar transporter 0.0031 0.0125 0.0168
Schistosoma mansoni alpha-1 adrenergic receptor 0.0048 0.0318 0.0428
Loa Loa (eye worm) hypothetical protein 0.0048 0.0318 0.0651
Leishmania major hypothetical protein, conserved 0.0031 0.0125 0.1258
Echinococcus granulosus peptide allatostatin:somatostatin 0.0048 0.0318 0.0404
Loa Loa (eye worm) G-protein coupled receptor 0.0048 0.0318 0.0651
Echinococcus granulosus neuropeptide FF receptor 2 0.0048 0.0318 0.0404
Schistosoma mansoni 6-phosphofructokinase 0.0109 0.099 0.1333
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0067 0.0524 0.048
Schistosoma mansoni glucose transport protein 0.0217 0.2193 0.2951
Leishmania major glucose transporter, lmgt3 0.0067 0.0533 0.5378
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0023 0.0045 0.0013
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0048 0.0318 0.0404
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0049 0.0357
Plasmodium vivax proline--tRNA ligase, putative 0.0076 0.0628 0.0585
Schistosoma mansoni hypothetical protein 0.0073 0.0592 0.0797
Trichomonas vaginalis glucose transporter, putative 0.0067 0.0533 0.1761
Trypanosoma cruzi hexose transporter, putative 0.0067 0.0533 0.5378
Loa Loa (eye worm) 6-phosphofructokinase 0.0109 0.099 0.2029
Onchocerca volvulus 0.0048 0.0318 0.0579
Loa Loa (eye worm) hypothetical protein 0.0026 0.0078 0.0159
Brugia malayi PHD-finger family protein 0.0222 0.2253 0.2864
Brugia malayi Bromodomain containing protein 0.0225 0.2279 0.2898
Loa Loa (eye worm) hypothetical protein 0.0042 0.0246 0.0505
Echinococcus granulosus g protein coupled receptor 0.0048 0.0318 0.0404
Echinococcus granulosus fmrfamide receptor 0.0048 0.0318 0.0404
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0048 0.0318 0.0404
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0067 0.0524 0.0731
Echinococcus multilocularis rhodopsin orphan GPCR 0.0048 0.0318 0.0404
Echinococcus multilocularis solute carrier family 22 0.0031 0.0125 0.0158
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0048 0.0318 0.0428
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0049 0.0493
Onchocerca volvulus 0.0031 0.0125 0.0163
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0125 0.0412
Loa Loa (eye worm) hypothetical protein 0.0065 0.0508 0.1042
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0065 0.0508 0.1681
Brugia malayi Bromodomain containing protein 0.0077 0.0635 0.0808
Leishmania major lysyl-tRNA synthetase, putative 0.0048 0.0323 0.3266
Plasmodium falciparum proline--tRNA ligase 0.0076 0.0628 0.0585
Loa Loa (eye worm) hypothetical protein 0.0083 0.0707 0.1449
Brugia malayi G protein-coupled receptor F59B2.13 0.0048 0.0318 0.0404
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0048 0.0318 0.0651
Loa Loa (eye worm) hypothetical protein 0.0034 0.0164 0.0336
Echinococcus granulosus neuropeptide Y receptor 0.0048 0.0318 0.0404
Echinococcus multilocularis dro:myosuppressin receptor 0.0048 0.0318 0.0404
Entamoeba histolytica phosphofructokinase, putative 0.0109 0.099 0.3275
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0049 0.0062
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0076 0.0628 0.6341
Schistosoma mansoni cpg binding protein 0.0029 0.0104 0.014
Schistosoma mansoni opsin-like receptor 0.0048 0.0318 0.0428
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0076 0.0628 0.0891
Loa Loa (eye worm) phosphofructokinase 0.0109 0.099 0.2029
Echinococcus multilocularis orexin receptor type 2 0.0048 0.0318 0.0404
Echinococcus granulosus cpg binding protein 0.0032 0.0144 0.0183
Brugia malayi Major Facilitator Superfamily protein 0.0031 0.0125 0.0158
Echinococcus granulosus 6 phosphofructokinase 0.0109 0.099 0.1259
Echinococcus granulosus tm gpcr rhodopsin 0.0048 0.0318 0.0404
Schistosoma mansoni amine GPCR 0.0048 0.0318 0.0428
Echinococcus granulosus rhodopsin orphan GPCR 0.0048 0.0318 0.0404
Leishmania major glucose transporter, lmgt1 0.0067 0.0533 0.5378
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0073 0.0592 0.5983
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0073 0.0592 0.5983
Schistosoma mansoni protein kinase 0.0066 0.0523 0.0704
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0023 0.0045 0.0141
Echinococcus multilocularis GPCR, family 3, C terminal 0.0026 0.0078 0.0099
Echinococcus multilocularis g protein coupled receptor 0.0048 0.0318 0.0404
Entamoeba histolytica phosphofructokinase, putative 0.0109 0.099 0.3275
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0029 0.0112 0.0101
Brugia malayi hypothetical protein 0.0048 0.0318 0.0404
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0049 0.0357
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0042 0.0246 0.0505
Trypanosoma cruzi hexose transporter, putative 0.0037 0.0194 0.1961
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0066 0.0523 0.0665
Echinococcus granulosus rhodopsin orphan GPCR 0.0048 0.0318 0.0404
Loa Loa (eye worm) hypothetical protein 0.0031 0.0125 0.0255
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0143 0.1368 1
Echinococcus granulosus peregrin 0.0225 0.2279 0.2898
Brugia malayi neuropeptide F receptor 0.0048 0.0318 0.0404
Echinococcus multilocularis somatostatin receptor 0.0048 0.0318 0.0404
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0048 0.0318 0.0428
Echinococcus granulosus rhodopsin orphan GPCR 0.0048 0.0318 0.0404
Echinococcus granulosus neuropeptides capa receptor 0.0048 0.0318 0.0404
Echinococcus granulosus dro:myosuppressin receptor 0.0048 0.0318 0.0404
Schistosoma mansoni glucose transporter 0.0031 0.0125 0.0168
Mycobacterium ulcerans sugar transporter 0.0031 0.0125 0.0911
Plasmodium falciparum lysine--tRNA ligase 0.0048 0.0323 0.0279
Onchocerca volvulus 0.0031 0.0125 0.0163
Loa Loa (eye worm) hypothetical protein 0.0048 0.0318 0.0651
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0048 0.0323 0.2365
Brugia malayi jmjC domain containing protein 0.0273 0.2811 0.3574
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0217 0.2193 0.2788
Plasmodium falciparum protein kinase 7 0.0613 0.6585 0.657
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0351 0.3675 0.3646
Onchocerca volvulus 0.0048 0.0318 0.0579
Echinococcus granulosus 7tm_1 domain containing protein 0.0048 0.0318 0.0404
Loa Loa (eye worm) hypothetical protein 0.0048 0.0318 0.0651
Schistosoma mansoni lysyl-tRNA synthetase 0.0048 0.0323 0.0435
Brugia malayi follicle stimulating hormone receptor 0.0048 0.0318 0.0404
Loa Loa (eye worm) hypothetical protein 0.0048 0.0318 0.0651
Plasmodium falciparum calcium-dependent protein kinase 3 0.0067 0.0524 0.048
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0049 0.0357
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0049 0.0062
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0041 0.0242 0.1491
Loa Loa (eye worm) hypothetical protein 0.0048 0.0318 0.0651
Onchocerca volvulus 0.0443 0.4692 1
Loa Loa (eye worm) hypothetical protein 0.0048 0.0318 0.0651
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0065 0.0508 0.0646
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0048 0.0318 0.0428
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0036 0.0184 0.0234
Loa Loa (eye worm) hypothetical protein 0.0048 0.0318 0.0651
Treponema pallidum fructose-bisphosphate aldolase 0.0292 0.3024 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0125 0.0255
Schistosoma mansoni protein kinase 0.0066 0.0523 0.0704
Onchocerca volvulus 0.0048 0.0318 0.0579
Schistosoma mansoni biogenic amine receptor 0.0048 0.0318 0.0428
Toxoplasma gondii histone lysine methyltransferase SET1 0.0057 0.0415 0.0566
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0125 0.0412
Echinococcus granulosus orexin receptor type 2 0.0048 0.0318 0.0404
Trypanosoma brucei glucose transporter, putative 0.0067 0.0533 0.5378
Loa Loa (eye worm) hypothetical protein 0.0048 0.0318 0.0651
Loa Loa (eye worm) hypothetical protein 0.0443 0.4692 0.9617
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0075 0.0622 0.079
Loa Loa (eye worm) hypothetical protein 0.0048 0.0318 0.0651
Schistosoma mansoni bromodomain containing protein 0.0065 0.0505 0.068
Loa Loa (eye worm) hypothetical protein 0.0048 0.0318 0.0651
Loa Loa (eye worm) hypothetical protein 0.0048 0.0318 0.0651
Brugia malayi Sugar transporter family protein 0.0217 0.2193 0.2788
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0048 0.0318 0.0428
Loa Loa (eye worm) 6-phosphofructokinase 0.0109 0.099 0.2029
Echinococcus granulosus neuropeptide receptor 0.0048 0.0318 0.0404
Echinococcus granulosus g protein coupled receptor 0.0048 0.0318 0.0404
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0048 0.0318 0.0579
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0031 0.0125 0.0168
Schistosoma mansoni hypothetical protein 0.0217 0.2193 0.2951
Loa Loa (eye worm) hypothetical protein 0.0443 0.4692 0.9617
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0031 0.0125 0.0911
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0066 0.0523 0.0665
Mycobacterium ulcerans 6-phosphofructokinase 0.0109 0.099 0.724
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0048 0.0318 0.0404
Schistosoma mansoni sugar transporter 0.0031 0.0125 0.0168
Schistosoma mansoni jumonji domain containing protein 0.0072 0.0582 0.0784
Brugia malayi Bromodomain containing protein 0.0038 0.021 0.0268
Echinococcus granulosus tachykinin peptides receptor 99D 0.0048 0.0318 0.0404
Loa Loa (eye worm) neuropeptide F receptor 0.0048 0.0318 0.0651
Echinococcus multilocularis solute carrier family 22 0.0031 0.0125 0.0158
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0048 0.0318 0.0428
Brugia malayi jmjC domain containing protein 0.0072 0.0582 0.0741
Echinococcus granulosus calcium dependent protein kinase 0.0062 0.0478 0.0607
Brugia malayi neuropeptide F receptor 0.0048 0.0318 0.0404
Leishmania major ATP-dependent phosphofructokinase 0.0109 0.099 1
Echinococcus granulosus solute carrier family 22 0.0031 0.0125 0.0158
Loa Loa (eye worm) hypothetical protein 0.0381 0.4015 0.8229
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0351 0.3675 0.555
Onchocerca volvulus 0.0048 0.0318 0.0579
Echinococcus granulosus synaptic vesicle 2 protein 0.0031 0.0125 0.0158
Onchocerca volvulus 0.0048 0.0318 0.0579
Loa Loa (eye worm) hypothetical protein 0.0048 0.0318 0.0651
Loa Loa (eye worm) hypothetical protein 0.0048 0.0318 0.0651
Loa Loa (eye worm) hypothetical protein 0.0044 0.0277 0.0567
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0109 0.099 0.724
Echinococcus granulosus L aminoadipate semialdehyde 0.0083 0.0707 0.0899
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0112 0.0369
Echinococcus granulosus alpha 1A adrenergic receptor 0.0048 0.0318 0.0404
Loa Loa (eye worm) hypothetical protein 0.0071 0.057 0.1167
Schistosoma mansoni zinc finger protein 0.0021 0.0021 0.0029
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0048 0.0318 0.0404
Loa Loa (eye worm) hypothetical protein 0.0048 0.0318 0.0651
Leishmania major glucose transporter/membrane transporter D2, putative 0.0067 0.0533 0.5378
Schistosoma mansoni neuropeptide receptor 0.0048 0.0318 0.0428
Loa Loa (eye worm) hypothetical protein 0.0048 0.0318 0.0651
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0136 0.129 0.164
Brugia malayi Dopamine receptor protein 2 0.0048 0.0318 0.0404
Echinococcus multilocularis rhodopsin orphan GPCR 0.0048 0.0318 0.0404
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0048 0.0318 0.0404
Trypanosoma cruzi sugar transporter, putative 0.0031 0.0125 0.1258
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0031 0.0125 0.0158
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0125 0.0412
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0109 0.099 1
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0048 0.0318 0.0404
Echinococcus granulosus metabotropic glutamate receptor 5 0.0199 0.1996 0.2538
Trichomonas vaginalis phosphofructokinase, putative 0.0109 0.099 0.3275
Echinococcus granulosus tm gpcr rhodopsin 0.0048 0.0318 0.0404

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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