TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 301.426 | Formula: C18H27N3O
H donors: 0 H acceptors: 1 LogP: 1.49 Rotable bonds: 5
Rule of 5 violations (Lipinski): 1
SMILES: O=C1CCN(CCN1CCN1CCCC1)Cc1ccccc1
InChi: 1S/C18H27N3O/c22-18-8-11-20(16-17-6-2-1-3-7-17)13-15-21(18)14-12-19-9-4-5-10-19/h1-3,6-7H,4-5,8-16H2
InChiKey: QSDQYBXKBXIMNQ-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Schistosoma mansoni	protein tyrosine phosphatase	0.0122	0.0126	0.4182
Echinococcus granulosus	receptor type tyrosine protein phosphatase	0.0122	0.0126	0.0126
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0122	0.0126	0.0126
Trichomonas vaginalis	serine/threonine-protein kinase wnk, putative	0.0045	0	0.5
Brugia malayi	Lethal protein 805	0.0122	0.0126	0.0126
Trichomonas vaginalis	br serine/threonine-protein kinase, putative	0.0045	0	0.5
Echinococcus multilocularis	Netrin receptor DCC	0.0122	0.0126	0.0126
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Trichomonas vaginalis	protein tyrosine kinase, putative	0.0045	0	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Loa Loa (eye worm)	hypothetical protein	0.0211	0.0274	0.0274
Echinococcus multilocularis	receptor type tyrosine protein phosphatase	0.0122	0.0126	0.0126
Echinococcus granulosus	Down syndrome cell adhesion molecule	0.0122	0.0126	0.0126
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Echinococcus multilocularis	tyrosine protein kinase	0.6105	1	1
Brugia malayi	hypothetical protein	0.0122	0.0126	0.0126
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Schistosoma mansoni	hypothetical protein	0.0228	0.0302	1
Schistosoma mansoni	receptor tyrosine phosphatase type r2a	0.0122	0.0126	0.4182
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Schistosoma mansoni	titin	0.0122	0.0126	0.4182
Onchocerca volvulus		0.0122	0.0126	0.2511
Loa Loa (eye worm)	immunoglobulin I-set domain-containing protein	0.0122	0.0126	0.0126
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Plasmodium falciparum	protein kinase, putative	0.0045	0	0.5
Onchocerca volvulus		0.0122	0.0126	0.2511
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Onchocerca volvulus		0.0122	0.0126	0.2511
Trichomonas vaginalis	conserved hypothetical protein	0.0045	0	0.5
Echinococcus multilocularis	Fibronectin type III domain containing protein	0.0122	0.0126	0.0126
Brugia malayi	Fibronectin type III domain containing protein	0.0122	0.0126	0.0126
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0122	0.0126	0.0126
Schistosoma mansoni	cell adhesion molecule	0.0122	0.0126	0.4182
Trichomonas vaginalis	ankyrin repeat-containing protein, putative	0.0045	0	0.5
Toxoplasma gondii	STE kinase	0.0045	0	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Schistosoma mansoni	nephrin	0.0122	0.0126	0.4182
Leishmania major	hypothetical protein, conserved	0.0122	0.0126	0.2082
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Schistosoma mansoni	tripartite motif protein trim9	0.0122	0.0126	0.4182
Schistosoma mansoni	receptor protein tyrosine phosphatase	0.0122	0.0126	0.4182
Schistosoma mansoni	serine/threonine protein kinase	0.0122	0.0126	0.4182
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Brugia malayi	SPRY domain containing protein	0.0122	0.0126	0.0126
Echinococcus multilocularis	receptor type tyrosine protein phosphatase	0.0122	0.0126	0.0126
Echinococcus multilocularis	neuroglian	0.0122	0.0126	0.0126
Echinococcus granulosus	G1Y162 protein	0.0122	0.0126	0.0126
Echinococcus multilocularis	roundabout 2	0.0122	0.0126	0.0126
Trypanosoma cruzi	Fibronectin type III domain containing protein, putative	0.0122	0.0126	0.2082
Loa Loa (eye worm)	immunoglobulin I-set domain-containing protein	0.0122	0.0126	0.0126
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Onchocerca volvulus		0.0228	0.0302	0.6005
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Echinococcus granulosus	titin	0.0122	0.0126	0.0126
Loa Loa (eye worm)	hypothetical protein	0.0122	0.0126	0.0126
Toxoplasma gondii	calcium dependent protein kinase CDPK8	0.0045	0	0.5
Echinococcus granulosus	fibronectin type III domain-containing protein	0.0122	0.0126	0.0126
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Trypanosoma cruzi	C-8 sterol isomerase, putative	0.0413	0.0607	1
Brugia malayi	hypothetical protein	0.0228	0.0302	0.0302
Brugia malayi	Fibronectin type III domain containing protein	0.0122	0.0126	0.0126
Brugia malayi	Twik (KCNK-like) family of potassium channels, alpha subunit 30.	0.0122	0.0126	0.0126
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Loa Loa (eye worm)	hypothetical protein	0.0122	0.0126	0.0126
Echinococcus granulosus	insulin growth factor 1 receptor beta	0.0167	0.0201	0.0201
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0122	0.0126	0.0126
Loa Loa (eye worm)	hypothetical protein	0.0122	0.0126	0.0126
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Plasmodium falciparum	protein kinase, putative	0.0045	0	0.5
Brugia malayi	myotactin form A	0.0122	0.0126	0.0126
Schistosoma mansoni	receptor tyrosine phosphatase type r2a	0.0122	0.0126	0.4182
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Echinococcus granulosus	Fibronectin type III	0.0122	0.0126	0.0126
Echinococcus granulosus	contactin	0.0122	0.0126	0.0126
Onchocerca volvulus		0.035	0.0503	1
Schistosoma mansoni	hemicentin	0.0122	0.0126	0.4182
Trypanosoma cruzi	Fibronectin type III domain containing protein, putative	0.0122	0.0126	0.2082
Loa Loa (eye worm)	hypothetical protein	0.0122	0.0126	0.0126
Schistosoma mansoni	cell adhesion molecule	0.0122	0.0126	0.4182
Echinococcus granulosus	roundabout 2	0.0122	0.0126	0.0126
Trichomonas vaginalis	protein kinase atn1, putative	0.0045	0	0.5
Schistosoma mansoni	factor for adipocyte differentiation	0.0122	0.0126	0.4182
Leishmania major	C-8 sterol isomerase-like protein	0.0413	0.0607	1
Echinococcus granulosus	receptor type tyrosine protein phosphatase	0.0122	0.0126	0.0126
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Loa Loa (eye worm)	hypothetical protein	0.0122	0.0126	0.0126
Echinococcus granulosus	EG95	0.0122	0.0126	0.0126
Brugia malayi	Fibronectin type III domain containing protein	0.0122	0.0126	0.0126
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Schistosoma mansoni	hypothetical protein	0.0122	0.0126	0.4182
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0122	0.0126	0.0126
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0122	0.0126	0.0126
Echinococcus granulosus	cell adhesion molecule	0.0122	0.0126	0.0126
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Plasmodium vivax	tyrosine kinase-like protein, putative	0.0045	0	0.5
Echinococcus granulosus	Netrin receptor DCC	0.0122	0.0126	0.0126
Brugia malayi	Fibronectin type III domain containing protein	0.0122	0.0126	0.0126
Trichomonas vaginalis	STE family protein kinase	0.0045	0	0.5
Loa Loa (eye worm)	hypothetical protein	0.0122	0.0126	0.0126
Loa Loa (eye worm)	hypothetical protein	0.0122	0.0126	0.0126
Schistosoma mansoni	factor for adipocyte differentiation	0.0122	0.0126	0.4182
Schistosoma mansoni	ephrin receptor	0.0167	0.0201	0.6653
Loa Loa (eye worm)	hypothetical protein	0.0228	0.0302	0.0302
Echinococcus multilocularis	Netrin receptor DCC	0.0122	0.0126	0.0126
Echinococcus multilocularis	Down syndrome cell adhesion molecule	0.0122	0.0126	0.0126
Toxoplasma gondii	protein kinase domain-containing protein	0.0045	0	0.5
Echinococcus granulosus	anosmin 1	0.0122	0.0126	0.0126
Trypanosoma brucei	C-8 sterol isomerase, putative	0.0413	0.0607	1
Loa Loa (eye worm)	lethal protein 805	0.0122	0.0126	0.0126
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Loa Loa (eye worm)	UNCoordinated family member	0.0122	0.0126	0.0126
Brugia malayi	myotactin form B	0.0122	0.0126	0.0126
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Onchocerca volvulus		0.0122	0.0126	0.2511
Loa Loa (eye worm)	immunoglobulin I-set domain-containing protein	0.0122	0.0126	0.0126
Schistosoma mansoni	receptor tyrosine phosphatase type r2a	0.0122	0.0126	0.4182
Loa Loa (eye worm)	hypothetical protein	0.0122	0.0126	0.0126
Loa Loa (eye worm)	myotactin form A	0.0122	0.0126	0.0126
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0122	0.0126	0.0126
Toxoplasma gondii	Tyrosine kinase-like (TKL) protein	0.0045	0	0.5
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0122	0.0126	0.0126
Brugia malayi	Lethal protein 805	0.0122	0.0126	0.0126
Trichomonas vaginalis	CAMK family protein kinase	0.0045	0	0.5
Echinococcus granulosus	usherin	0.0122	0.0126	0.0126
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Echinococcus multilocularis	titin	0.0122	0.0126	0.0126
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Onchocerca volvulus		0.0122	0.0126	0.2511
Echinococcus granulosus	anosmin 1	0.0122	0.0126	0.0126
Onchocerca volvulus		0.0122	0.0126	0.2511
Echinococcus granulosus	anosmin 1	0.0122	0.0126	0.0126
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0122	0.0126	0.0126
Echinococcus multilocularis	contactin neuroglian septate junction protein	0.0122	0.0126	0.0126
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Echinococcus multilocularis	usherin	0.0122	0.0126	0.0126
Schistosoma mansoni	cell adhesion molecule	0.0122	0.0126	0.4182
Onchocerca volvulus		0.0122	0.0126	0.2511
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Schistosoma mansoni	neuroglian	0.0122	0.0126	0.4182
Plasmodium falciparum	tyrosine kinase-like protein	0.0045	0	0.5
Echinococcus granulosus	nephrin	0.0122	0.0126	0.0126
Plasmodium vivax	protein kinase, putative	0.0045	0	0.5
Trichomonas vaginalis	AGC family protein kinase	0.0045	0	0.5
Loa Loa (eye worm)	TK/ALK protein kinase	0.1951	0.3145	0.3145
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Echinococcus granulosus	Phosphotidylinositol phosphatase PTPRQ	0.0122	0.0126	0.0126
Brugia malayi	Fibronectin type III domain containing protein	0.0122	0.0126	0.0126
Onchocerca volvulus		0.0122	0.0126	0.2511
Echinococcus multilocularis	roundabout 2	0.0122	0.0126	0.0126
Loa Loa (eye worm)	hypothetical protein	0.0122	0.0126	0.0126
Echinococcus multilocularis	roundabout 2	0.0122	0.0126	0.0126
Loa Loa (eye worm)	hypothetical protein	0.0228	0.0302	0.0302
Schistosoma mansoni	myosin-binding protein-related	0.0122	0.0126	0.4182
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Echinococcus granulosus	roundabout 2	0.0122	0.0126	0.0126
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Trypanosoma cruzi	hypothetical protein, conserved	0.0122	0.0126	0.2082
Loa Loa (eye worm)	CAMK/MLCK protein kinase	0.0122	0.0126	0.0126
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Echinococcus multilocularis	anosmin 1	0.0122	0.0126	0.0126
Loa Loa (eye worm)	hypothetical protein	0.0122	0.0126	0.0126
Schistosoma mansoni	hypothetical protein	0.0228	0.0302	1
Echinococcus granulosus	Fibronectin type III domain containing protein	0.0122	0.0126	0.0126
Echinococcus multilocularis	receptor type tyrosine protein phosphatase zeta	0.0122	0.0126	0.0126
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0122	0.0126	0.0126
Loa Loa (eye worm)	hypothetical protein	0.0122	0.0126	0.0126
Echinococcus multilocularis	titin	0.0122	0.0126	0.0126
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0122	0.0126	0.0126
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Echinococcus multilocularis	fibronectin type III domain-containing protein	0.0122	0.0126	0.0126
Trichomonas vaginalis	conserved hypothetical protein	0.0045	0	0.5
Loa Loa (eye worm)	fibronectin type III domain-containing protein	0.0122	0.0126	0.0126
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Echinococcus granulosus	tyrosine protein kinase	0.6105	1	1
Loa Loa (eye worm)	hypothetical protein	0.0413	0.0607	0.0607
Giardia lamblia	Kinase, NEK	0.0045	0	0.5
Trichomonas vaginalis	conserved hypothetical protein	0.0045	0	0.5
Loa Loa (eye worm)	hypothetical protein	0.606	0.9925	0.9925
Echinococcus multilocularis	anosmin 1	0.0122	0.0126	0.0126
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Trichomonas vaginalis	serine-threonine protein kinase, putative	0.0045	0	0.5
Schistosoma mansoni	hypothetical protein	0.0122	0.0126	0.4182
Trichomonas vaginalis	conserved hypothetical protein	0.0045	0	0.5
Brugia malayi	ERG2 and Sigma1 receptor like protein	0.0413	0.0607	0.0607
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Echinococcus multilocularis	cell adhesion molecule	0.0122	0.0126	0.0126
Trichomonas vaginalis	conserved hypothetical protein	0.0045	0	0.5
Brugia malayi	hypothetical protein	0.0122	0.0126	0.0126
Loa Loa (eye worm)	hypothetical protein	0.0228	0.0302	0.0302
Brugia malayi	Protein kinase domain containing protein	0.1952	0.3146	0.3146
Loa Loa (eye worm)	hypothetical protein	0.0122	0.0126	0.0126
Echinococcus granulosus	roundabout 2	0.0122	0.0126	0.0126
Loa Loa (eye worm)	hypothetical protein	0.0122	0.0126	0.0126
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Brugia malayi	protein-tyrosine phosphatase Lar-like precursor, putative	0.0122	0.0126	0.0126
Loa Loa (eye worm)	hypothetical protein	0.0122	0.0126	0.0126
Echinococcus multilocularis	insulin growth factor 1 receptor beta	0.0167	0.0201	0.0201
Loa Loa (eye worm)	CAMK protein kinase	0.0122	0.0126	0.0126
Loa Loa (eye worm)	TK protein kinase	0.6105	1	1
Echinococcus granulosus	neuroglian	0.0122	0.0126	0.0126
Loa Loa (eye worm)	hypothetical protein	0.0122	0.0126	0.0126
Brugia malayi	protein unc-22	0.0122	0.0126	0.0126
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Onchocerca volvulus		0.0122	0.0126	0.2511
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Loa Loa (eye worm)	fibronectin type III domain-containing protein	0.0122	0.0126	0.0126
Giardia lamblia	Kinase, NEK	0.0045	0	0.5
Trypanosoma brucei	Fibronectin type III domain containing protein, putative	0.0122	0.0126	0.2082
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0048	0.0005	1
Plasmodium falciparum	tyrosine kinase-like protein	0.0045	0	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0122	0.0126	0.0126
Schistosoma mansoni	cell adhesion molecule	0.0122	0.0126	0.4182
Brugia malayi	Twik (KCNK-like) family of potassium channels, alpha subunit 32	0.0122	0.0126	0.0126
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Echinococcus multilocularis	Phosphotidylinositol phosphatase PTPRQ	0.0122	0.0126	0.0126
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Loa Loa (eye worm)	hypothetical protein	0.0122	0.0126	0.0126
Toxoplasma gondii	Tyrosine kinase-like (TKL) protein	0.0045	0	0.5
Echinococcus multilocularis	transfer RNA-Phe	0.0122	0.0126	0.0126
Schistosoma mansoni	factor for adipocyte differentiation	0.0122	0.0126	0.4182
Schistosoma mansoni	titin	0.0122	0.0126	0.4182
Echinococcus granulosus	receptor type tyrosine protein phosphatase zeta	0.0122	0.0126	0.0126
Loa Loa (eye worm)	immunoglobulin I-set domain-containing protein	0.0122	0.0126	0.0126
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Echinococcus multilocularis	Receptor type tyrosine protein phosphatase O	0.0122	0.0126	0.0126
Onchocerca volvulus		0.0122	0.0126	0.2511
Loa Loa (eye worm)	fibronectin type III domain-containing protein	0.0122	0.0126	0.0126
Echinococcus granulosus	Netrin receptor DCC	0.0122	0.0126	0.0126
Plasmodium vivax	tyrosine kinase-like protein, putative	0.0045	0	0.5
Brugia malayi	Fibronectin type III domain containing protein	0.0122	0.0126	0.0126
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Giardia lamblia	Protein 21.1	0.0045	0	0.5
Onchocerca volvulus		0.0122	0.0126	0.2511
Schistosoma mansoni	hypothetical protein	0.0122	0.0126	0.4182
Plasmodium falciparum	protein kinase, putative	0.0045	0	0.5
Schistosoma mansoni	titin	0.0122	0.0126	0.4182
Onchocerca volvulus		0.0122	0.0126	0.2511
Loa Loa (eye worm)	hypothetical protein	0.0122	0.0126	0.0126
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Loa Loa (eye worm)	hypothetical protein	0.0122	0.0126	0.0126
Schistosoma mansoni	cell adhesion molecule	0.0122	0.0126	0.4182
Trichomonas vaginalis	TK family protein kinase	0.0045	0	0.5
Echinococcus multilocularis	MAM	0.0228	0.0302	0.0302
Echinococcus granulosus	receptor type tyrosine protein phosphatase	0.0122	0.0126	0.0126
Entamoeba histolytica	tyrosin kinase, putative	0.0048	0.0005	1
Loa Loa (eye worm)	immunoglobulin I-set domain-containing protein	0.0122	0.0126	0.0126
Loa Loa (eye worm)	fibronectin type III domain-containing protein	0.0122	0.0126	0.0126
Echinococcus multilocularis	receptor type tyrosine protein phosphatase F	0.0122	0.0126	0.0126
Schistosoma mansoni	receptor tyrosine phosphatase type r2a	0.0122	0.0126	0.4182
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0122	0.0126	0.0126
Echinococcus granulosus	titin	0.0122	0.0126	0.0126
Trichomonas vaginalis	conserved hypothetical protein	0.0045	0	0.5
Loa Loa (eye worm)	hypothetical protein	0.0122	0.0126	0.0126
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Echinococcus multilocularis	Fibronectin, type III	0.0122	0.0126	0.0126
Onchocerca volvulus		0.0122	0.0126	0.2511
Schistosoma mansoni	nephrin	0.0122	0.0126	0.4182
Loa Loa (eye worm)	hypothetical protein	0.0122	0.0126	0.0126
Toxoplasma gondii	protein kinase	0.0045	0	0.5
Echinococcus granulosus	MAM	0.0228	0.0302	0.0302
Loa Loa (eye worm)	hypothetical protein	0.1678	0.2694	0.2694
Trichomonas vaginalis	conserved hypothetical protein	0.0045	0	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Brugia malayi	Protein-tyrosine phosphatase	0.0122	0.0126	0.0126
Loa Loa (eye worm)	CAMK/MLCK protein kinase	0.0122	0.0126	0.0126
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Loa Loa (eye worm)	hypothetical protein	0.0122	0.0126	0.0126
Echinococcus multilocularis	anosmin 1	0.0122	0.0126	0.0126
Trichomonas vaginalis	TKL family protein kinase	0.0045	0	0.5
Echinococcus granulosus	Phosphotidylinositol phosphatase PTPRQ	0.0122	0.0126	0.0126
Loa Loa (eye worm)	projectin	0.0122	0.0126	0.0126
Echinococcus multilocularis	receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type	0.0122	0.0126	0.0126
Giardia lamblia	Kinase	0.0045	0	0.5

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

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External resources for this compound

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Bibliographic References

No literature references available for this target.

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Detailed information for compound 806876