Detailed information for compound 833873

Basic information

Technical information
  • TDR Targets ID: 833873
  • Name: N-(4-chlorophenyl)-3-methyl-1-oxoisochroman-3 -carboxamide
  • MW: 315.751 | Formula: C17H14ClNO3
  • H donors: 1 H acceptors: 2 LogP: 3.56 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: Clc1ccc(cc1)NC(=O)C1(C)OC(=O)c2c(C1)cccc2
  • InChi: 1S/C17H14ClNO3/c1-17(16(21)19-13-8-6-12(18)7-9-13)10-11-4-2-3-5-14(11)15(20)22-17/h2-9H,10H2,1H3,(H,19,21)
  • InChiKey: SDZATQGETSTEFC-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-(4-chlorophenyl)-3-methyl-1-oxo-isochroman-3-carboxamide
  • N-(4-chlorophenyl)-3-methyl-1-oxo-3-isochromancarboxamide
  • N-(4-chlorophenyl)-1-keto-3-methyl-isochroman-3-carboxamide
  • 3-Methyl-1-oxo-isochroman-3-carboxylic acid (4-chloro-phenyl)-amide
  • BAS 09687627
  • STOCK4S-59691

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0163 0.0681 0.2259
Echinococcus multilocularis snurportin 1 0.0316 0.1371 0.1766
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0041 0.0036
Schistosoma mansoni survival motor neuron protein 0.0047 0.0155 0.0193
Onchocerca volvulus 0.0464 0.2043 0.8979
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0163 0.0681 0.2259
Echinococcus granulosus apoptotic protease activating factor 1 0.0126 0.0513 0.0661
Loa Loa (eye worm) Smad1 0.0016 0.0015 0.0015
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0163 0.0681 0.2259
Trypanosoma brucei C-8 sterol isomerase, putative 0.2222 1 1
Brugia malayi Cell death protein 3 precursor 0.0126 0.0513 0.0508
Entamoeba histolytica hypothetical protein 0.0163 0.0681 0.2862
Trypanosoma cruzi C-8 sterol isomerase, putative 0.2222 1 1
Brugia malayi Histone deacetylase family protein 0.0045 0.0145 0.014
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0219 0.0932 0.0927
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0163 0.0681 0.0681
Schistosoma mansoni ran 0.0022 0.0041 0.0046
Schistosoma mansoni caspase-7 (C14 family) 0.0126 0.0513 0.0655
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0702 0.3119 0.3091
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0163 0.0681 0.2862
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0702 0.3119 0.3091
Trypanosoma cruzi major cysteine proteinase, putative 0.0349 0.1525 0.1503
Echinococcus granulosus Smad4 0.0016 0.0015 0.002
Brugia malayi Cathepsin L-like precursor 0.0515 0.2275 0.2271
Giardia lamblia Cathepsin B precursor 0.0163 0.0681 0.2259
Echinococcus multilocularis geminin 0.0677 0.3009 0.3876
Entamoeba histolytica cysteine protease, putative 0.0214 0.0912 0.3899
Giardia lamblia Cathepsin B precursor 0.0647 0.2871 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0515 0.2275 0.7894
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0515 0.2275 0.7894
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0515 0.2275 0.2931
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0515 0.2275 0.7894
Schistosoma mansoni hypothetical protein 0.0047 0.0155 0.0193
Onchocerca volvulus Cathepsin F homolog 0.0515 0.2275 1
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0051 0.0035
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0091 0.0354 0.0456
Loa Loa (eye worm) MH2 domain-containing protein 0.0016 0.0015 0.0015
Schistosoma mansoni cathepsin F (C01 family) 0.0515 0.2275 0.2926
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0163 0.0681 0.087
Onchocerca volvulus Cathepsin L homolog 0.0163 0.0681 0.2974
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0354 0.0449
Giardia lamblia Cathepsin B precursor 0.0163 0.0681 0.2259
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0163 0.0681 0.2912
Trypanosoma cruzi histone deacetylase, putative 0.0045 0.0145 0.012
Entamoeba histolytica cysteine protease, putative 0.0163 0.0681 0.2862
Loa Loa (eye worm) hypothetical protein 0.0464 0.2043 0.2043
Leishmania major cathepsin L-like protease 0.0515 0.2275 0.2255
Giardia lamblia Cysteine protease 0.0163 0.0681 0.2259
Echinococcus multilocularis tar DNA binding protein 0.0065 0.0236 0.0304
Schistosoma mansoni smad1 5 8 and 0.0016 0.0015 0.0013
Echinococcus multilocularis importin subunit beta 1 0.003 0.0077 0.0099
Onchocerca volvulus 0.0515 0.2275 1
Leishmania major GTP-binding protein, putative 0.0022 0.0041 0.0016
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0702 0.3119 0.3091
Echinococcus granulosus cathepsin b 0.1728 0.7762 1
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0515 0.2275 0.2275
Onchocerca volvulus 0.0219 0.0932 0.4083
Giardia lamblia Cathepsin B precursor 0.0163 0.0681 0.2259
Entamoeba histolytica cysteine protease, putative 0.0163 0.0681 0.2862
Brugia malayi Papain family cysteine protease containing protein 0.0163 0.0681 0.0675
Entamoeba histolytica cysteine protease, putative 0.0163 0.0681 0.2862
Entamoeba histolytica cysteine proteinase, putative 0.0214 0.0912 0.3899
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0163 0.0681 0.2912
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0214 0.0912 0.1169
Loa Loa (eye worm) hypothetical protein 0.0219 0.0932 0.0932
Schistosoma mansoni hypothetical protein 0.0126 0.0513 0.0655
Giardia lamblia Cathepsin L-like protease 0.0163 0.0681 0.2259
Echinococcus granulosus survival motor neuron protein 1 0.023 0.0983 0.1266
Plasmodium falciparum serine repeat antigen 5 0.0163 0.0681 0.2912
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0163 0.0681 0.2912
Loa Loa (eye worm) histone deacetylase 7A 0.0045 0.0145 0.0145
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1728 0.7762 0.7756
Loa Loa (eye worm) hypothetical protein 0.1728 0.7762 0.7762
Entamoeba histolytica cysteine protease, putative 0.0163 0.0681 0.2862
Loa Loa (eye worm) hypothetical protein 0.0464 0.2043 0.2043
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0236 0.0297
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0515 0.2275 0.7894
Echinococcus granulosus dnaJ subfamily B 0.0396 0.1737 0.2237
Plasmodium falciparum serine repeat antigen 2 0.0163 0.0681 0.2912
Echinococcus multilocularis cathepsin L 0.0163 0.0681 0.0877
Leishmania major cathepsin L-like protease 0.0515 0.2275 0.2255
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0163 0.0681 0.087
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1728 0.7762 1
Brugia malayi RNA, U transporter 1 0.0084 0.0323 0.0318
Toxoplasma gondii cathepsin CPC2 0.0163 0.0681 0.2356
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0515 0.2275 0.7894
Loa Loa (eye worm) hypothetical protein 0.0051 0.0175 0.0175
Brugia malayi Importin beta-1 subunit 0.003 0.0077 0.0071
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0163 0.0681 0.2912
Leishmania major cathepsin L-like protease 0.0702 0.3119 0.3102
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0316 0.1371 0.1371
Plasmodium vivax histone deacetylase, putative 0.0045 0.0145 0.0532
Loa Loa (eye worm) cathepsin B 0.0647 0.2871 0.2871
Echinococcus granulosus lamin 0.0026 0.0061 0.0079
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0236 0.0297
Onchocerca volvulus 0.0047 0.0155 0.0658
Trichomonas vaginalis conserved hypothetical protein 0.0163 0.0681 0.2259
Brugia malayi Smad1 0.0016 0.0015 0.001
Giardia lamblia Cathepsin L precursor 0.0163 0.0681 0.2259
Giardia lamblia Cathepsin L precursor 0.0163 0.0681 0.2259
Brugia malayi RNA recognition motif domain containing protein 0.0065 0.0236 0.023
Toxoplasma gondii cathepsin CPL 0.0515 0.2275 0.7921
Brugia malayi RNA binding protein 0.0065 0.0236 0.023
Brugia malayi MH2 domain containing protein 0.0016 0.0015 0.001
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0163 0.0681 0.087
Entamoeba histolytica cysteine protease, putative 0.0214 0.0912 0.3899
Schistosoma mansoni importin beta-1 0.003 0.0077 0.0092
Onchocerca volvulus 0.0515 0.2275 1
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0163 0.0681 0.0681
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0163 0.0681 0.2912
Plasmodium falciparum cysteine proteinase falcipain 3 0.0515 0.2275 1
Loa Loa (eye worm) TAR-binding protein 0.0065 0.0236 0.0236
Entamoeba histolytica cysteine protease, putative 0.0214 0.0912 0.3899
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0702 0.3119 0.3091
Plasmodium vivax serine-repeat antigen (SERA) 0.0163 0.0681 0.2912
Onchocerca volvulus 0.0026 0.0061 0.0245
Echinococcus granulosus inhibitor of apoptosis protein 0.0219 0.0932 0.1201
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0214 0.0912 0.1169
Giardia lamblia Hypothetical protein 0.0163 0.0681 0.2259
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0041 0.0125
Giardia lamblia Cathepsin L-like protease 0.0163 0.0681 0.2259
Loa Loa (eye worm) hypothetical protein 0.0126 0.0513 0.0513
Brugia malayi MH2 domain containing protein 0.0016 0.0015 0.001
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0163 0.0681 0.087
Echinococcus multilocularis microtubule associated protein 2 0.0699 0.3108 0.4004
Echinococcus multilocularis tissue type plasminogen activator 0.0018 0.0026 0.0033
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.0255 0.1095 0.1095
Onchocerca volvulus 0.0163 0.0681 0.2974
Giardia lamblia Cathepsin L precursor 0.0163 0.0681 0.2259
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0041 0.0053
Trypanosoma cruzi cysteine peptidase, putative 0.0515 0.2275 0.2255
Onchocerca volvulus Cathepsin L homolog 0.0515 0.2275 1
Brugia malayi cathepsin F-like cysteine proteinase 0.0051 0.0175 0.0169
Trypanosoma brucei cysteine peptidase C (CPC) 0.0647 0.2871 0.2841
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0702 0.3119 0.3091
Entamoeba histolytica cysteine protease, putative 0.0515 0.2275 1
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0163 0.0681 0.2259
Schistosoma mansoni histone deacetylase 4 5 0.0045 0.0145 0.018
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.0077 0.0248
Leishmania major C-8 sterol isomerase-like protein 0.2222 1 1
Brugia malayi cathepsin L precursor 0.0163 0.0681 0.0675
Schistosoma mansoni hypothetical protein 0.0396 0.1737 0.2232
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0163 0.0681 0.2259
Entamoeba histolytica cysteine proteinase, putative 0.0214 0.0912 0.3899
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0354 0.0449
Schistosoma mansoni cpg binding protein 0.0028 0.0069 0.0082
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0091 0.0354 0.0456
Schistosoma mansoni hypothetical protein 0.0219 0.0932 0.1195
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0163 0.0681 0.2259
Toxoplasma gondii kringle domain-containing protein 0.0018 0.0026 0.007
Onchocerca volvulus 0.0028 0.0069 0.0279
Schistosoma mansoni ran 0.0022 0.0041 0.0046
Onchocerca volvulus 0.0515 0.2275 1
Onchocerca volvulus Cathepsin L homolog 0.0515 0.2275 1
Loa Loa (eye worm) MH2 domain-containing protein 0.0235 0.1005 0.1005
Trypanosoma cruzi cysteine proteinase, putative 0.0214 0.0912 0.0889
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0041 0.007
Toxoplasma gondii preprocathepsin c precursor, putative 0.0163 0.0681 0.2356
Echinococcus granulosus cathepsin L cysteine proteinase 0.0515 0.2275 0.2931
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0163 0.0681 0.2912
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0647 0.2871 0.2852
Schistosoma mansoni smad1 5 8 and 0.0016 0.0015 0.0013
Brugia malayi Kringle domain containing protein 0.0018 0.0026 0.002
Echinococcus multilocularis laminin 0.0014 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.0126 0.0513 0.0513
Schistosoma mansoni histone deacetylase hda2 0.0045 0.0145 0.018
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0041 0.0053
Brugia malayi Protein kinase domain containing protein 0.0018 0.0026 0.002
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0163 0.0681 0.087
Schistosoma mansoni cpg binding protein 0.0029 0.0076 0.0091
Echinococcus multilocularis p2X purinoceptor 4 0.0067 0.0246 0.0317
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0515 0.2275 0.7894
Echinococcus multilocularis lamin dm0 0.0026 0.0061 0.0079
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0163 0.0681 0.2912
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0091 0.0354 0.0456
Trypanosoma brucei histone deacetylase, putative 0.0045 0.0145 0.0104
Echinococcus multilocularis caspase 2 0.0126 0.0513 0.0661
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0163 0.0681 0.2259
Loa Loa (eye worm) cytochrome P450 family protein 0.0022 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0018 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0163 0.0681 0.0681
Echinococcus multilocularis p2X purinoceptor 4 0.0067 0.0246 0.0317
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0091 0.0354 0.0349
Plasmodium falciparum serine repeat antigen 8 0.0163 0.0681 0.2912
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0219 0.0932 0.0927
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0041 0.007
Plasmodium falciparum serine repeat antigen 3 0.0163 0.0681 0.2912
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0163 0.0681 0.2259
Entamoeba histolytica cysteine protease, putative 0.0214 0.0912 0.3899
Plasmodium vivax unspecified product 0.0214 0.0912 0.3942
Brugia malayi hypothetical protein 0.023 0.0983 0.0978
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0163 0.0681 0.2259
Leishmania major cathepsin L-like protease 0.0702 0.3119 0.3102
Onchocerca volvulus 0.0126 0.0513 0.2238
Loa Loa (eye worm) transcription factor SMAD2 0.0235 0.1005 0.1005
Plasmodium falciparum histone deacetylase 2 0.0045 0.0145 0.0532
Plasmodium falciparum serine repeat antigen 1 0.0163 0.0681 0.2912
Trypanosoma brucei Aph-1 protein, putative 0.0099 0.0392 0.0352
Echinococcus granulosus histone deacetylase 0.0045 0.0145 0.0187
Echinococcus multilocularis fibrillin 1 0.0014 0.0006 0.0007
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0077 0.0035
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0702 0.3119 0.3091
Schistosoma mansoni Smad4 0.0016 0.0015 0.0013
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0016 0.0015 0.0013
Schistosoma mansoni P2X receptor subunit 0.0067 0.0246 0.031
Echinococcus multilocularis lamin 0.0026 0.0061 0.0079
Giardia lamblia Cysteine protease 0.0163 0.0681 0.2259
Trypanosoma cruzi histone deacetylase, putative 0.0045 0.0145 0.012
Entamoeba histolytica cysteine protease, putative 0.0214 0.0912 0.3899
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0163 0.0681 0.2259
Toxoplasma gondii cathepsin CPC1 0.0163 0.0681 0.2356
Giardia lamblia Cathepsin L precursor 0.0163 0.0681 0.2259
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0051 0.0035
Giardia lamblia Hypothetical protein 0.0163 0.0681 0.2259
Loa Loa (eye worm) hypothetical protein 0.0045 0.0145 0.0145
Brugia malayi Papain family cysteine protease containing protein 0.0163 0.0681 0.0675
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0163 0.0681 0.2259
Giardia lamblia Cathepsin B precursor 0.0647 0.2871 1
Brugia malayi Cathepsin L-like precursor 0.0515 0.2275 0.2271
Echinococcus multilocularis musashi 0.0026 0.0061 0.0079
Entamoeba histolytica cysteine protease, putative 0.0163 0.0681 0.2862
Schistosoma mansoni cathepsin F (C01 family) 0.0464 0.2043 0.2627
Brugia malayi Cathepsin L-like precursor 0.0464 0.2043 0.2039
Schistosoma mansoni intermediate filament proteins 0.0026 0.0061 0.0072
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0163 0.0681 0.2912
Brugia malayi intermediate filament protein 0.0026 0.0061 0.0056
Schistosoma mansoni histone deacetylase 4 5 0.0045 0.0145 0.018
Giardia lamblia Cathepsin L precursor 0.0163 0.0681 0.2259
Entamoeba histolytica cysteine protease, putative 0.0214 0.0912 0.3899
Brugia malayi TAR-binding protein 0.0065 0.0236 0.023
Loa Loa (eye worm) histone deacetylase 0.0045 0.0145 0.0145
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0041 0.0016
Plasmodium falciparum cysteine proteinase falcipain 1 0.0214 0.0912 0.3942
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0014 0.0006 0.0006
Onchocerca volvulus Deterin homolog 0.0219 0.0932 0.4083
Echinococcus multilocularis inhibitor of apoptosis protein 0.0219 0.0932 0.1201
Echinococcus multilocularis gamma secretase subunit aph 1 0.0255 0.1095 0.1411
Plasmodium vivax unspecified product 0.0163 0.0681 0.2912
Echinococcus multilocularis cysteine protease 0.0515 0.2275 0.2931
Schistosoma mansoni P2X receptor subunit 0.0067 0.0246 0.031
Echinococcus granulosus histone deacetylase 6 0.0045 0.0145 0.0187
Echinococcus granulosus p2X purinoceptor 4 0.0067 0.0246 0.0317
Echinococcus multilocularis apoptotic protease activating factor 1 0.0126 0.0513 0.0661
Entamoeba histolytica cysteine proteinase, putative 0.0464 0.2043 0.8962
Echinococcus granulosus tar DNA binding protein 0.0065 0.0236 0.0304
Loa Loa (eye worm) hypothetical protein 0.0014 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0051 0.0175 0.0175
Loa Loa (eye worm) hypothetical protein 0.0163 0.0681 0.0681
Leishmania major cathepsin L-like protease 0.0702 0.3119 0.3102
Brugia malayi cathepsin F-like cysteine proteinase 0.0163 0.0681 0.0675
Trypanosoma cruzi Aph-1 protein, putative 0.0099 0.0392 0.0367
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0651 0.2887 0.2869
Onchocerca volvulus 0.0515 0.2275 1
Brugia malayi cathepsin B-like cysteine proteinase 0.1728 0.7762 0.7761
Loa Loa (eye worm) hypothetical protein 0.0515 0.2275 0.2275
Schistosoma mansoni cpg binding protein 0.0029 0.0076 0.0091
Brugia malayi cathepsin Z-like cysteine proteinase 0.0163 0.0681 0.0675
Leishmania major cathepsin L-like protease 0.0515 0.2275 0.2255
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0163 0.0681 0.2259
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0163 0.0681 0.2912
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0219 0.0932 0.1201
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0051 0.0175 0.0169
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0041 0.0041
Schistosoma mansoni hypothetical protein 0.0316 0.1371 0.176
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0464 0.2043 0.7075
Toxoplasma gondii histone deacetylase HDAC1 0.0045 0.0145 0.0488
Schistosoma mansoni cathepsin S (C01 family) 0.0163 0.0681 0.087
Brugia malayi CXXC zinc finger family protein 0.0028 0.0069 0.0063
Loa Loa (eye worm) MH1 domain-containing protein 0.0016 0.0015 0.0015
Plasmodium vivax unspecified product 0.0051 0.0175 0.0663
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0515 0.2275 0.7894
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0515 0.2275 0.7894
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0051 0.0035
Entamoeba histolytica cysteine protease, putative 0.0214 0.0912 0.3899
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0214 0.0912 0.3078
Giardia lamblia Encystation-specific protease 0.0163 0.0681 0.2259
Schistosoma mansoni cathepsin s 0.0051 0.0175 0.0218
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0515 0.2275 0.7894
Echinococcus granulosus laminin 0.0014 0.0006 0.0007
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0515 0.2275 0.2931
Brugia malayi Histone deacetylase family protein 0.0045 0.0145 0.014
Echinococcus granulosus snurportin 1 0.0316 0.1371 0.1766
Entamoeba histolytica cysteine protease, putative 0.0214 0.0912 0.3899
Entamoeba histolytica hypothetical protein 0.0024 0.0051 0.0045
Echinococcus granulosus histone deacetylase 7 0.0045 0.0145 0.0187
Echinococcus granulosus cathepsin l cysteine peptidase 0.0515 0.2275 0.2931
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0214 0.0912 0.0875
Schistosoma mansoni hypothetical protein 0.0677 0.3009 0.3872
Schistosoma mansoni cathepsin F (C01 family) 0.0515 0.2275 0.2926
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0163 0.0681 0.2259
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0214 0.0912 0.3078
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0515 0.2275 0.7894
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0515 0.2275 1
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0163 0.0681 0.2259
Echinococcus granulosus histone deacetylase 6 0.0045 0.0145 0.0187
Loa Loa (eye worm) hypothetical protein 0.0163 0.0681 0.0681
Echinococcus granulosus p2X purinoceptor 4 0.0067 0.0246 0.0317
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0163 0.0681 0.087
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0515 0.2275 0.7894
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0091 0.0354 0.0354
Loa Loa (eye worm) hypothetical protein 0.0163 0.0681 0.0681
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0515 0.2275 0.7894
Echinococcus multilocularis Tolloid protein 1 0.0014 0.0006 0.0007
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0163 0.0681 0.2259
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0061 0.0061
Plasmodium vivax serine-repeat antigen (SERA) 0.0163 0.0681 0.2912
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0702 0.3119 0.3091
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0214 0.0912 0.0875
Entamoeba histolytica cysteine protease, putative 0.0214 0.0912 0.3899
Schistosoma mansoni smad1 5 8 and 0.0016 0.0015 0.0013
Plasmodium falciparum serine repeat antigen 6 0.0163 0.0681 0.2912
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0006 0.0006
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0155 0.015
Entamoeba histolytica cysteine protease, putative 0.0214 0.0912 0.3899
Onchocerca volvulus 0.0515 0.2275 1
Schistosoma mansoni hypothetical protein 0.0677 0.3009 0.3872
Echinococcus granulosus intermediate filament protein 0.0026 0.0061 0.0079
Loa Loa (eye worm) fibroinase 0.0515 0.2275 0.2275
Brugia malayi Cathepsin L-like precursor 0.0515 0.2275 0.2271
Schistosoma mansoni smad 0.0016 0.0015 0.0013
Schistosoma mansoni hypothetical protein 0.0018 0.0026 0.0026
Brugia malayi hypothetical protein 0.0126 0.0513 0.0508
Schistosoma mansoni inhibitor of apoptosis protein 0.0219 0.0932 0.1195
Schistosoma mansoni P2X receptor subunit 0.0067 0.0246 0.031
Schistosoma mansoni lamin 0.0026 0.0061 0.0072
Brugia malayi MH1 domain containing protein 0.0016 0.0015 0.001
Echinococcus multilocularis cathepsin b 0.1728 0.7762 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0163 0.0681 0.2259
Loa Loa (eye worm) hypothetical protein 0.0014 0.0006 0.0006
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0236 0.0297
Echinococcus multilocularis cysteine protease 0.0515 0.2275 0.2931
Plasmodium falciparum serine repeat antigen 7 0.0163 0.0681 0.2912
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0163 0.0681 0.087
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0515 0.2275 0.7894
Echinococcus granulosus cathepsin l1 0.0464 0.2043 0.2632
Entamoeba histolytica cysteine proteinase, putative 0.0214 0.0912 0.3899
Echinococcus multilocularis smad 0.0016 0.0015 0.002
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0006 0.0001
Brugia malayi Cathepsin L-like precursor 0.0515 0.2275 0.2271
Schistosoma mansoni gamma-secretase subunit aph-1 0.0255 0.1095 0.1404
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0163 0.0681 0.0681
Echinococcus multilocularis Smad4 0.0016 0.0015 0.002
Trypanosoma cruzi cysteine peptidase, putative 0.0702 0.3119 0.3102
Brugia malayi cathepsin L-like cysteine proteinase 0.0163 0.0681 0.0675
Onchocerca volvulus 0.0026 0.0061 0.0245
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0069 0.0069
Echinococcus multilocularis cpg binding protein 0.0029 0.0076 0.0098
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0515 0.2275 1
Brugia malayi Cathepsin L-like precursor 0.0515 0.2275 0.2271
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0163 0.0681 0.087
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0214 0.0912 0.1169
Echinococcus granulosus caspase 2 0.0126 0.0513 0.0661
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0515 0.2275 0.7894
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0219 0.0932 0.1201
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0515 0.2275 0.7894
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0515 0.2275 0.7894
Echinococcus granulosus cathepsin L 0.0214 0.0912 0.1175
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0702 0.3119 0.3091
Brugia malayi Papain family cysteine protease containing protein 0.0214 0.0912 0.0907
Trypanosoma brucei histone deacetylase 3 0.0045 0.0145 0.0104
Giardia lamblia Cysteine protease 0.0163 0.0681 0.2259
Echinococcus multilocularis dnaJ subfamily B 0.0396 0.1737 0.2237
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0163 0.0681 0.2912
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0515 0.2275 0.7894
Trypanosoma cruzi cysteine peptidase, putative 0.0051 0.0175 0.0149
Loa Loa (eye worm) hypothetical protein 0.0026 0.0061 0.0061
Echinococcus granulosus mothers against decapentaplegic 5 0.0016 0.0015 0.002
Brugia malayi cathepsin L-like precursor 0.0464 0.2043 0.2039
Brugia malayi fibroinase precursor 0.0163 0.0681 0.0675
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0163 0.0681 0.0675
Entamoeba histolytica cysteine protease, putative 0.0163 0.0681 0.2862
Echinococcus multilocularis cathepsin L cysteine protease 0.0515 0.2275 0.2931
Plasmodium falciparum serine repeat antigen 4 0.0163 0.0681 0.2912
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0515 0.2275 0.7894
Entamoeba histolytica cysteine proteinase 2 0.0214 0.0912 0.3899
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1728 0.7762 1
Loa Loa (eye worm) cysteine protease 0.0515 0.2275 0.2275
Loa Loa (eye worm) hypothetical protein 0.0014 0.0006 0.0006
Giardia lamblia Cathepsin B precursor 0.0647 0.2871 1
Trypanosoma cruzi cysteine proteinase, putative 0.0214 0.0912 0.0889
Echinococcus granulosus tissue type plasminogen activator 0.0018 0.0026 0.0033
Entamoeba histolytica cysteine proteinase, putative 0.0515 0.2275 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0515 0.2275 0.7894
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0647 0.2871 0.2852
Plasmodium falciparum importin beta, putative 0.003 0.0077 0.0227
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0219 0.0932 0.1195
Entamoeba histolytica cysteine proteinase, putative 0.0515 0.2275 1
Giardia lamblia Cathepsin L precursor 0.0163 0.0681 0.2259
Plasmodium vivax vivapain-2 0.0515 0.2275 1
Echinococcus multilocularis mothers against decapentaplegic 5 0.0016 0.0015 0.002
Plasmodium vivax importin-beta 2, putative 0.003 0.0077 0.0227
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.1728 0.7762 1
Echinococcus multilocularis histone deacetylase 6 0.0045 0.0145 0.0187
Schistosoma mansoni microtubule-associated protein tau 0.0699 0.3108 0.3999
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0163 0.0681 0.2912
Entamoeba histolytica cysteine protease, putative 0.0214 0.0912 0.3899
Echinococcus granulosus smad 0.0016 0.0015 0.002
Loa Loa (eye worm) hypothetical protein 0.1136 0.5083 0.5083
Loa Loa (eye worm) hypothetical protein 0.0464 0.2043 0.2043
Loa Loa (eye worm) ctsf protein 0.0515 0.2275 0.2275
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0065 0.0236 0.0236
Brugia malayi MH1 domain containing protein 0.0016 0.0015 0.001
Brugia malayi MH2 domain containing protein 0.0235 0.1005 0.1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0702 0.3119 0.3091
Loa Loa (eye worm) hypothetical protein 0.0026 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0163 0.0681 0.0681
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0163 0.0681 0.2259
Echinococcus granulosus geminin 0.0677 0.3009 0.3876
Echinococcus multilocularis cathepsin L cysteine protease 0.0515 0.2275 0.2931
Plasmodium vivax vivapain-1 0.0214 0.0912 0.3942
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0163 0.0681 0.2912
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1728 0.7762 1
Brugia malayi Cathepsin L-like cysteine proteinase 0.0464 0.2043 0.2039
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0163 0.0681 0.2259
Echinococcus granulosus histone deacetylase 6 0.0045 0.0145 0.0187
Trypanosoma cruzi cysteine peptidase, putative 0.0702 0.3119 0.3102
Echinococcus granulosus cpg binding protein 0.0029 0.0076 0.0098
Trypanosoma cruzi cysteine peptidase, putative 0.0214 0.0912 0.0889
Leishmania major cathepsin L-like protease 0.0515 0.2275 0.2255
Plasmodium vivax vivapain-3 0.0214 0.0912 0.3942
Echinococcus multilocularis cathepsin b 0.1728 0.7762 1
Echinococcus granulosus microtubule associated protein 2 0.0699 0.3108 0.4004
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0163 0.0681 0.2862
Leishmania major importin beta-1 subunit, putative 0.0024 0.0051 0.0026
Plasmodium falciparum serine repeat antigen 9 0.0163 0.0681 0.2912
Echinococcus granulosus importin subunit beta 1 0.003 0.0077 0.0099
Echinococcus multilocularis survival motor neuron protein 1 0.023 0.0983 0.1266
Loa Loa (eye worm) hypothetical protein 0.0219 0.0932 0.0932
Echinococcus granulosus Tolloid protein 1 0.0014 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.003 0.0077 0.0077
Giardia lamblia Cathepsin B precursor 0.0163 0.0681 0.2259
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0515 0.2275 0.7894
Echinococcus granulosus cathepsin L 0.0163 0.0681 0.0877
Loa Loa (eye worm) hypothetical protein 0.0163 0.0681 0.0681
Loa Loa (eye worm) TK/ROR protein kinase 0.0018 0.0026 0.0026
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0515 0.2275 0.7894
Plasmodium vivax vivapain-2 0.0515 0.2275 1
Echinococcus granulosus lamin dm0 0.0026 0.0061 0.0079
Echinococcus granulosus cysteine protease 0.0214 0.0912 0.1175
Brugia malayi Cathepsin L-like precursor 0.0051 0.0175 0.0169
Loa Loa (eye worm) hypothetical protein 0.023 0.0983 0.0983
Echinococcus multilocularis cathepsin L 0.0214 0.0912 0.1175
Brugia malayi Cathepsin L-like precursor 0.0464 0.2043 0.2039
Loa Loa (eye worm) hypothetical protein 0.0045 0.0145 0.0145
Giardia lamblia Cysteine protease 0.0163 0.0681 0.2259
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0702 0.3119 0.3091
Trypanosoma cruzi cruzipain precursor, putative 0.0051 0.0175 0.0149
Onchocerca volvulus 0.0515 0.2275 1
Trypanosoma cruzi cysteine peptidase, putative 0.0702 0.3119 0.3102
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0214 0.0912 0.0889
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0061 0.0061
Echinococcus multilocularis histone deacetylase 6 0.0045 0.0145 0.0187
Schistosoma mansoni lamin 0.0026 0.0061 0.0072
Schistosoma mansoni cathepsin C 0.0163 0.0681 0.087
Brugia malayi Papain family cysteine protease containing protein 0.0515 0.2275 0.2271
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0702 0.3119 0.3091
Echinococcus granulosus cathepsin l1 0.0515 0.2275 0.2931
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0515 0.2275 0.2275
Plasmodium falciparum histone deacetylase, putative 0.0045 0.0145 0.0532
Echinococcus multilocularis p2X purinoceptor 4 0.0067 0.0246 0.0317
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0061 0.0056
Brugia malayi Cytochrome P450 family protein 0.0022 0.0042 0.0037
Trypanosoma cruzi Aph-1 protein, putative 0.0099 0.0392 0.0367
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0236 0.0297
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0163 0.0681 0.2259
Echinococcus granulosus TGF beta signal transducer SmadC 0.0016 0.0015 0.002
Brugia malayi Papain family cysteine protease containing protein 0.0163 0.0681 0.0675
Leishmania major cysteine peptidase A (CPA) 0.0515 0.2275 0.2255
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0647 0.2871 0.3694
Entamoeba histolytica cysteine protease, putative 0.0214 0.0912 0.3899
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0515 0.2275 0.7894
Echinococcus multilocularis histone deacetylase 7 0.0045 0.0145 0.0187
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0014 0.0006 0.0006
Onchocerca volvulus Cell death protein 3 homolog 0.0126 0.0513 0.2238
Loa Loa (eye worm) hypothetical protein 0.2222 1 1
Schistosoma mansoni P2X receptor subunit 0.0067 0.0246 0.031
Toxoplasma gondii histone lysine methyltransferase SET1 0.0053 0.0182 0.0614
Trypanosoma cruzi major cysteine proteinase, putative 0.0163 0.0681 0.0657
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.0014 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0014 0.0006 0.0006
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0163 0.0681 0.087
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0016 0.0015 0.002
Loa Loa (eye worm) hypothetical protein 0.0014 0.0006 0.0006
Entamoeba histolytica cysteine proteinase 1, putative 0.0214 0.0912 0.3899
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0051 0.0026
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0163 0.0681 0.2259
Entamoeba histolytica cysteine proteinase, putative 0.0214 0.0912 0.3899
Trichomonas vaginalis conserved hypothetical protein 0.0163 0.0681 0.2259
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0163 0.0681 0.2912
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0464 0.2043 0.7075
Toxoplasma gondii cathepsin B 0.0647 0.2871 1
Trypanosoma cruzi cysteine protease, putative 0.0214 0.0912 0.0889
Leishmania major histone deacetylase, putative 0.0045 0.0145 0.012
Plasmodium vivax histone deacetylase 2, putative 0.0045 0.0145 0.0532
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0515 0.2275 0.7894
Onchocerca volvulus 0.0515 0.2275 1
Brugia malayi cathepsin Z-like cysteine proteinase 0.0163 0.0681 0.0675
Loa Loa (eye worm) RNA binding protein 0.0065 0.0236 0.0236
Brugia malayi Cathepsin L-like precursor 0.0515 0.2275 0.2271
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0515 0.2275 0.7894
Echinococcus granulosus cathepsin b 0.1728 0.7762 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0354 0.0449
Entamoeba histolytica cysteine protease, putative 0.0214 0.0912 0.3899
Onchocerca volvulus 0.0018 0.0026 0.0088
Trypanosoma cruzi histone deacetylase, putative 0.0045 0.0145 0.012
Trypanosoma brucei histone deacetylase 4 0.0045 0.0145 0.0104
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0051 0.0175 0.0175
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0041 0.0016
Brugia malayi Papain family cysteine protease containing protein 0.0214 0.0912 0.0907
Leishmania major cathepsin L-like protease 0.0515 0.2275 0.2255
Schistosoma mansoni cathepsin B (C01 family) 0.0163 0.0681 0.087
Echinococcus granulosus cathepsin L cysteine protease 0.0214 0.0912 0.1175
Leishmania major histone deacetylase, putative 0.0045 0.0145 0.012
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0515 0.2275 0.7894
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0059 0.021 0.0264
Brugia malayi gamma-secretase subunit aph-1 0.0255 0.1095 0.109
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0091 0.0354 0.0456
Giardia lamblia Cathepsin B precursor 0.0163 0.0681 0.2259
Echinococcus granulosus gamma secretase subunit aph 1 0.0255 0.1095 0.1411
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0077 0.0035
Echinococcus granulosus p2X purinoceptor 4 0.0067 0.0246 0.0317
Loa Loa (eye worm) hypothetical protein 0.0051 0.0175 0.0175
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0163 0.0681 0.2259
Echinococcus multilocularis histone deacetylase 6 0.0045 0.0145 0.0187
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0647 0.2871 1
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0236 0.0297
Echinococcus multilocularis histone deacetylase 0.0045 0.0145 0.0187
Trypanosoma cruzi cruzipain precursor, putative 0.0702 0.3119 0.3102

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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