Detailed information for compound 834340

Basic information

Technical information
  • TDR Targets ID: 834340
  • Name: 2-(2-bromo-4-ethylphenoxy)-N-[[3-(3-methylphe nyl)-1,2,4-oxadiazol-5-yl]methyl]-N-propan-2- ylacetamide
  • MW: 472.375 | Formula: C23H26BrN3O3
  • H donors: 0 H acceptors: 3 LogP: 5.48 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCc1ccc(c(c1)Br)OCC(=O)N(C(C)C)Cc1onc(n1)c1cccc(c1)C
  • InChi: 1S/C23H26BrN3O3/c1-5-17-9-10-20(19(24)12-17)29-14-22(28)27(15(2)3)13-21-25-23(26-30-21)18-8-6-7-16(4)11-18/h6-12,15H,5,13-14H2,1-4H3
  • InChiKey: PBLSQQXWOZYWEA-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 2-(2-bromo-4-ethyl-phenoxy)-N-isopropyl-N-[[3-(3-methylphenyl)-1,2,4-oxadiazol-5-yl]methyl]acetamide
  • 2-(2-bromo-4-ethylphenoxy)-N-isopropyl-N-[[3-(3-methylphenyl)-1,2,4-oxadiazol-5-yl]methyl]acetamide
  • 2-(2-bromo-4-ethyl-phenoxy)-N-[[3-(3-methylphenyl)-1,2,4-oxadiazol-5-yl]methyl]-N-propan-2-yl-ethanamide
  • STK300695

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus peptide allatostatin:somatostatin 0.0129 0.0412 0.0736
Mycobacterium ulcerans esterase/lipase LipP 0.0073 0.0188 0.1877
Echinococcus multilocularis fmrfamide receptor 0.0129 0.0412 0.0736
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0251 0.0895 0.0887
Schistosoma mansoni growth hormone secretagogue receptor 0.0129 0.0412 0.0736
Schistosoma mansoni twik family of potassium channels-related 0.0036 0.0044 0.0063
Echinococcus granulosus g protein coupled receptor 0.0129 0.0412 0.0736
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0037 0.0048 0.0003
Echinococcus multilocularis neuropeptide FF receptor 2 0.0129 0.0412 0.0736
Brugia malayi GnHR receptor homolog 0.0129 0.0412 0.0402
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.0895 0.8866
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0129 0.0412 0.0404
Brugia malayi G protein-coupled receptor 0.0129 0.0412 0.0402
Loa Loa (eye worm) hypothetical protein 0.0129 0.0412 0.0404
Echinococcus granulosus Two pore potassium channel protein sup 9 0.0036 0.0044 0.0063
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0152 0.0502 0.0902
Echinococcus multilocularis neuropeptide Y receptor 0.0129 0.0412 0.0736
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0052 0.0107 0.0107
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0865 0.332 0.6069
Schistosoma mansoni hypothetical protein 0.0678 0.2581 0.4714
Echinococcus granulosus histone acetyltransferase KAT2B 0.0144 0.0469 0.0842
Loa Loa (eye worm) hypothetical protein 0.0129 0.0412 0.0404
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0129 0.0412 0.0736
Echinococcus multilocularis rhodopsin orphan GPCR 0.0129 0.0412 0.0736
Brugia malayi hypothetical protein 0.0129 0.0412 0.0402
Loa Loa (eye worm) hypothetical protein 0.0129 0.0412 0.0404
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.0588 0.5671
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.0895 0.8866
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0553 0.5305
Onchocerca volvulus 0.0036 0.0044 0.063
Onchocerca volvulus 0.0129 0.0412 0.7395
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0129 0.0412 0.0404
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0129 0.0412 0.0404
Echinococcus multilocularis neuropeptide s receptor 0.0129 0.0412 0.0736
Echinococcus multilocularis mitogen activated protein kinase 0.0052 0.0107 0.0177
Echinococcus multilocularis L aminoadipate semialdehyde 0.0089 0.0252 0.0443
Brugia malayi neuropeptide F receptor 0.0129 0.0412 0.0402
Mycobacterium ulcerans glutaminase 0.0279 0.1003 1
Plasmodium falciparum potassium channel 0.0036 0.0044 0.752
Loa Loa (eye worm) hypothetical protein 0.0129 0.0412 0.0404
Loa Loa (eye worm) hypothetical protein 0.1306 0.5063 0.5059
Schistosoma mansoni twik family of potassium channels-related 0.0036 0.0044 0.0063
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0129 0.0412 0.0736
Loa Loa (eye worm) hypothetical protein 0.0129 0.0412 0.0404
Brugia malayi hypothetical protein 0.0129 0.0412 0.0402
Onchocerca volvulus Neuropeptide F receptor homolog 0.0129 0.0412 0.7395
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0037 0.0048 0.0027
Echinococcus granulosus tm gpcr rhodopsin 0.0129 0.0412 0.0736
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0052 0.0107 0.5671
Schistosoma mansoni calcium-activated potassium channel 0.0036 0.0044 0.0063
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0129 0.0412 0.0404
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0084 0.0234 0.1814
Echinococcus multilocularis somatostatin receptor 0.0129 0.0412 0.0736
Loa Loa (eye worm) hypothetical protein 0.0073 0.0188 0.018
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0129 0.0412 0.0736
Echinococcus granulosus 7TM GPCR rhodopsin 0.0129 0.0412 0.0736
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0129 0.0412 0.0736
Echinococcus granulosus tachykinin peptides receptor 99D 0.0129 0.0412 0.0736
Brugia malayi hypothetical protein 0.0129 0.0412 0.0402
Brugia malayi hypothetical protein 0.0038 0.0053 0.0043
Loa Loa (eye worm) MH2 domain-containing protein 0.0362 0.133 0.1323
Mycobacterium ulcerans ion transport protein 0.0036 0.0044 0.0441
Schistosoma mansoni sodium/chloride dependent transporter 0.0088 0.025 0.044
Loa Loa (eye worm) hypothetical protein 0.0247 0.0876 0.0869
Loa Loa (eye worm) hypothetical protein 0.0036 0.0044 0.0036
Loa Loa (eye worm) hypothetical protein 0.0036 0.0044 0.0036
Echinococcus granulosus calcium activated potassium channel variant 0.0036 0.0044 0.0063
Trypanosoma cruzi C-8 sterol isomerase, putative 0.2555 1 1
Mycobacterium tuberculosis Probable lipase LipD 0.0073 0.0188 0.1086
Loa Loa (eye worm) G-protein coupled receptor 0.0129 0.0412 0.0404
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0073 0.0188 0.0327
Onchocerca volvulus 0.0155 0.0513 0.9255
Entamoeba histolytica hypothetical protein 0.0038 0.0053 0.0411
Loa Loa (eye worm) hypothetical protein 0.0073 0.0188 0.018
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.0588 0.5671
Echinococcus multilocularis twik family of potassium channels 0.0036 0.0044 0.0063
Echinococcus multilocularis calcium activated potassium channel variant 0.0036 0.0044 0.0063
Echinococcus multilocularis potassium channel subfamily K 0.0036 0.0044 0.0063
Loa Loa (eye worm) hypothetical protein 0.0088 0.025 0.0242
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0025 0 0.5
Loa Loa (eye worm) hypothetical protein 0.0073 0.0188 0.018
Schistosoma mansoni amine GPCR 0.0129 0.0412 0.0736
Echinococcus multilocularis serotonin receptor 0.0247 0.0876 0.1588
Loa Loa (eye worm) hypothetical protein 0.0036 0.0044 0.0036
Loa Loa (eye worm) glutaminase 0.0279 0.1003 0.0996
Onchocerca volvulus 0.0073 0.0188 0.3283
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0037 0.0048 0.8082
Loa Loa (eye worm) G-protein coupled receptor 0.0129 0.0412 0.0404
Loa Loa (eye worm) hypothetical protein 0.0036 0.0044 0.0036
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0037 0.0048 0.0069
Echinococcus granulosus tm gpcr rhodopsin 0.0129 0.0412 0.0736
Loa Loa (eye worm) melatonin receptor type 1A 0.0129 0.0412 0.0404
Brugia malayi hypothetical protein 0.0131 0.0418 0.0408
Onchocerca volvulus Huntingtin homolog 0.0131 0.0418 0.7512
Brugia malayi beta-lactamase family protein 0.0073 0.0188 0.0178
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0129 0.0412 0.0736
Schistosoma mansoni biogenic amine receptor 0.0129 0.0412 0.0736
Schistosoma mansoni histamine h1 receptor 0.0129 0.0412 0.0736
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0092 0.0266 0.0258
Loa Loa (eye worm) hypothetical protein 0.0073 0.0188 0.018
Schistosoma mansoni twik family of potassium channels-related 0.0036 0.0044 0.0063
Mycobacterium ulcerans hypothetical protein 0.0073 0.0188 0.1877
Schistosoma mansoni myosin xvIII 0.0129 0.0412 0.0736
Plasmodium falciparum potassium channel 0.0036 0.0044 0.752
Onchocerca volvulus 0.0036 0.0044 0.063
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0129 0.0412 0.0736
Loa Loa (eye worm) hypothetical protein 0.0129 0.0412 0.0404
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 17 0.0036 0.0044 0.0034
Loa Loa (eye worm) hypothetical protein 0.0036 0.0044 0.0036
Plasmodium vivax potassium channel, putative 0.0036 0.0044 0.2352
Onchocerca volvulus 0.0036 0.0044 0.063
Loa Loa (eye worm) hypothetical protein 0.0036 0.0044 0.0036
Leishmania major calcium/potassium channel (CAKC), putative 0.0036 0.0044 0.0044
Loa Loa (eye worm) serotonin transporter b 0.0088 0.025 0.0242
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0129 0.0412 0.0736
Schistosoma mansoni hypothetical protein 0.0129 0.0412 0.0736
Loa Loa (eye worm) hypothetical protein 0.0036 0.0044 0.0036
Schistosoma mansoni neuropeptide receptor 0.0129 0.0412 0.0736
Loa Loa (eye worm) hypothetical protein 0.0129 0.0412 0.0404
Loa Loa (eye worm) hypothetical protein 0.0036 0.0044 0.0036
Echinococcus granulosus hypothetical protein 0.0129 0.0412 0.0736
Schistosoma mansoni biogenic amine (5HT) receptor 0.0247 0.0876 0.1588
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0129 0.0412 0.0736
Schistosoma mansoni calcium-activated potassium channel 0.0705 0.2689 0.4912
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0052 0.0107 0.0063
Onchocerca volvulus 0.0036 0.0044 0.063
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0038 0.0053 0.0079
Brugia malayi G-protein coupled receptor 0.0129 0.0412 0.0402
Loa Loa (eye worm) hypothetical protein 0.0129 0.0412 0.0404
Echinococcus granulosus geminin 0.0678 0.2581 0.4714
Loa Loa (eye worm) hypothetical protein 0.0798 0.3056 0.305
Echinococcus multilocularis dro:myosuppressin receptor 0.0129 0.0412 0.0736
Echinococcus multilocularis allatostatin A receptor 0.0129 0.0412 0.0736
Onchocerca volvulus 0.0129 0.0412 0.7395
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0092 0.0266 0.0469
Schistosoma mansoni neuropeptide receptor 0.0129 0.0412 0.0736
Echinococcus multilocularis potassium channel subfamily K 8 0.0036 0.0044 0.0063
Mycobacterium tuberculosis Conserved protein 0.0073 0.0188 0.1086
Loa Loa (eye worm) hypothetical protein 0.0073 0.0188 0.018
Loa Loa (eye worm) hypothetical protein 0.2555 1 1
Mycobacterium ulcerans NADH dehydrogenase I subunit F 0.019 0.0653 0.6504
Echinococcus multilocularis serotonin transporter 0.0088 0.025 0.044
Schistosoma mansoni transcription factor LCR-F1 0.0038 0.0053 0.0079
Mycobacterium ulcerans lipase LipD 0.0073 0.0188 0.1877
Loa Loa (eye worm) hypothetical protein 0.0036 0.0044 0.0036
Echinococcus multilocularis thyroid hormone receptor alpha 0.0164 0.055 0.0991
Schistosoma mansoni neuropeptide F-like receptor 0.0129 0.0412 0.0736
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0129 0.0412 0.0736
Onchocerca volvulus Huntingtin homolog 0.0131 0.0418 0.7512
Trichomonas vaginalis penicillin-binding protein, putative 0.0073 0.0188 0.1502
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0052 0.0107 0.0099
Loa Loa (eye worm) hypothetical protein 0.0129 0.0412 0.0404
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0129 0.0412 0.0736
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0084 0.0234 0.1814
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0038 0.0053 0.0079
Loa Loa (eye worm) neuropeptide F receptor 0.0129 0.0412 0.0404
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0129 0.0412 0.0402
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0129 0.0412 0.0736
Echinococcus multilocularis neuropeptides capa receptor 0.0129 0.0412 0.0736
Loa Loa (eye worm) hypothetical protein 0.0036 0.0044 0.0036
Echinococcus granulosus potassium channel subfamily K 0.0036 0.0044 0.0063
Echinococcus multilocularis acetylcholinesterase 0.0066 0.0163 0.0281
Echinococcus granulosus histone acetyltransferase KAT2B 0.0043 0.0073 0.0116
Echinococcus granulosus twik family of potassium channels 0.0036 0.0044 0.0063
Brugia malayi glutaminase DH11.1 0.0279 0.1003 0.0994
Brugia malayi hypothetical protein 0.0129 0.0412 0.0402
Loa Loa (eye worm) hypothetical protein 0.0088 0.025 0.0242
Trichomonas vaginalis NADH-ubiquinone oxidoreductase flavoprotein, putative 0.019 0.0653 0.6343
Leishmania major hypothetical protein, conserved 0.0073 0.0188 0.0188
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0037 0.0048 0.0069
Echinococcus multilocularis g-protein coupled receptor 0.0129 0.0412 0.0736
Brugia malayi hypothetical protein 0.0036 0.0044 0.0034
Brugia malayi Twik (KCNK-like) family of potasium channels, alpha subunit 40 0.0036 0.0044 0.0034
Loa Loa (eye worm) hypothetical protein 0.0334 0.122 0.1213
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0553 0.5305
Brugia malayi AKH receptor 0.0129 0.0412 0.0402
Loa Loa (eye worm) hypothetical protein 0.0028 0.001 0.0002
Brugia malayi Tachykinin-like peptides receptor 99D 0.0129 0.0412 0.0402
Onchocerca volvulus 0.0036 0.0044 0.063
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0037 0.0048 0.004
Echinococcus multilocularis Two pore potassium channel protein sup 9 0.0036 0.0044 0.0063
Loa Loa (eye worm) hypothetical protein 0.0129 0.0412 0.0404
Echinococcus multilocularis geminin 0.0678 0.2581 0.4714
Echinococcus granulosus sex peptide receptor 0.0129 0.0412 0.0736
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 35 0.0036 0.0044 0.0034
Echinococcus granulosus carboxylesterase 5A 0.0066 0.0163 0.0281
Entamoeba histolytica calcium-gated potassium channel protein, putative 0.0036 0.0044 0.0343
Loa Loa (eye worm) hypothetical protein 0.0036 0.0045 0.0037
Onchocerca volvulus 0.0089 0.0252 0.4454
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.01 0.0297 0.2299
Loa Loa (eye worm) transcription factor SMAD2 0.0362 0.133 0.1323
Loa Loa (eye worm) hypothetical protein 0.0129 0.0412 0.0404
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0129 0.0412 0.0736
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0107 0.0652
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0553 0.5305
Onchocerca volvulus 0.0129 0.0412 0.7395
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0352 0.1292 1
Echinococcus granulosus TWiK family of potassium channels protein 7 0.0036 0.0044 0.0063
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0037 0.0048 0.2528
Mycobacterium tuberculosis Probable NADH dehydrogenase I (chain F) NuoF (NADH-ubiquinone oxidoreductase chain F) 0.019 0.0653 0.3762
Echinococcus granulosus L aminoadipate semialdehyde 0.0089 0.0252 0.0443
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.0188 0.0145
Brugia malayi Serotonin receptor 0.0129 0.0412 0.0402
Loa Loa (eye worm) hypothetical protein 0.0129 0.0412 0.0404
Echinococcus granulosus allatostatin A receptor 0.0129 0.0412 0.0736
Schistosoma mansoni amine GPCR 0.0129 0.0412 0.0736
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0089 0.0252 0.0443
Brugia malayi NADH-ubiquinone oxidoreductase 51 kDa subunit, mitochondrial precursor 0.019 0.0653 0.0643
Loa Loa (eye worm) intermediate filament protein 0.0028 0.001 0.0002
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 30. 0.0036 0.0044 0.0034
Echinococcus multilocularis carboxylesterase 5A 0.0066 0.0163 0.0281
Brugia malayi exodeoxyribonuclease III family protein 0.0037 0.0048 0.0038
Loa Loa (eye worm) hypothetical protein 0.0066 0.0163 0.0155
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0251 0.0895 0.0885
Trichomonas vaginalis esterase, putative 0.0073 0.0188 0.1502
Schistosoma mansoni microtubule-associated protein tau 0.1408 0.5465 1
Schistosoma mansoni hypothetical protein 0.0036 0.0045 0.0064
Entamoeba histolytica hypothetical protein 0.0038 0.0053 0.0411
Trypanosoma brucei C-8 sterol isomerase, putative 0.2555 1 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0129 0.0412 0.0736
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0107 0.0652
Echinococcus granulosus G protein coupled receptor 139 0.0129 0.0412 0.0736
Mycobacterium tuberculosis Possible transmembrane cation transporter 0.0036 0.0044 0.0255
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.0188 0.0145
Echinococcus multilocularis orexin receptor type 2 0.0129 0.0412 0.0736
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 32 0.0036 0.0044 0.0034
Onchocerca volvulus 0.0073 0.0188 0.3283
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0088 0.025 0.024
Onchocerca volvulus 0.0036 0.0044 0.063
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0129 0.0412 0.0736
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0129 0.0412 0.0736
Loa Loa (eye worm) hypothetical protein 0.0129 0.0412 0.0404
Leishmania major NADH-ubiquinone oxidoreductase, mitochondrial, putative 0.019 0.0653 0.0653
Schistosoma mansoni NADH-ubiquinone oxidoreductase 0.019 0.0653 0.1178
Echinococcus granulosus twik family of potassium channels 0.0036 0.0044 0.0063
Echinococcus multilocularis mitogen activated protein kinase 3 0.0052 0.0107 0.0177
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0129 0.0412 0.0736
Trypanosoma brucei calcium/potassium channel (CAKC), putative 0.0036 0.0044 0.0044
Schistosoma mansoni calcium-activated potassium channel 0.0798 0.3056 0.5583
Echinococcus multilocularis rhodopsin orphan GPCR 0.0129 0.0412 0.0736
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0037 0.0048 0.073
Schistosoma mansoni twik family of potassium channels-related 0.0036 0.0044 0.0063
Brugia malayi latrophilin 2 splice variant baaae 0.0036 0.0045 0.0035
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0043 0.0073 0.0302
Leishmania major ion transport protein-like protein 0.0036 0.0044 0.0044
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0129 0.0412 0.0402
Trypanosoma brucei RNA helicase, putative 0.0148 0.0485 0.0485
Loa Loa (eye worm) hypothetical protein 0.0066 0.0163 0.0155
Echinococcus multilocularis microtubule associated protein 2 0.1408 0.5465 1
Loa Loa (eye worm) hypothetical protein 0.0057 0.0125 0.0117
Loa Loa (eye worm) solute carrier family 6 member 4 0.0088 0.025 0.0242
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 28 0.0036 0.0044 0.0034
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0073 0.0188 0.1877
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0129 0.0412 0.0736
Loa Loa (eye worm) hypothetical protein 0.0129 0.0412 0.0404
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 24 0.0036 0.0044 0.0034
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0129 0.0412 0.0402
Loa Loa (eye worm) hypothetical protein 0.0036 0.0044 0.0036
Echinococcus multilocularis rhodopsin orphan GPCR 0.0129 0.0412 0.0736
Brugia malayi acetyltransferase, GNAT family protein 0.0148 0.0486 0.0476
Echinococcus granulosus alpha 1A adrenergic receptor 0.0129 0.0412 0.0736
Brugia malayi hypothetical protein 0.0129 0.0412 0.0402
Loa Loa (eye worm) hypothetical protein 0.0129 0.0412 0.0404
Echinococcus granulosus 7tm_1 domain containing protein 0.0129 0.0412 0.0736
Leishmania major hypothetical protein, conserved 0.0036 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.0129 0.0412 0.0404
Echinococcus multilocularis rhodopsin orphan GPCR 0.0129 0.0412 0.0736
Echinococcus granulosus neuropeptides capa receptor 0.0129 0.0412 0.0736
Onchocerca volvulus 0.0129 0.0412 0.7395
Echinococcus multilocularis neuropeptide receptor A26 0.0129 0.0412 0.0736
Plasmodium vivax potassium channel, putative 0.0036 0.0044 0.2352
Echinococcus multilocularis g protein coupled receptor 0.0129 0.0412 0.0736
Onchocerca volvulus 0.0129 0.0412 0.7395
Brugia malayi Carboxylesterase family protein 0.0066 0.0163 0.0153
Schistosoma mansoni hypothetical protein 0.0148 0.0485 0.0871
Echinococcus multilocularis neuropeptides capa receptor 0.0129 0.0412 0.0736
Brugia malayi hypothetical protein 0.0129 0.0412 0.0402
Echinococcus granulosus neuropeptide receptor A26 0.0129 0.0412 0.0736
Brugia malayi Dopamine receptor protein 2 0.0129 0.0412 0.0402
Loa Loa (eye worm) hypothetical protein 0.0129 0.0412 0.0404
Loa Loa (eye worm) norepinephrine transporter 0.0088 0.025 0.0242
Schistosoma mansoni hypothetical protein 0.0129 0.0412 0.0736
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0129 0.0412 0.0736
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0148 0.0486 0.0872
Loa Loa (eye worm) hypothetical protein 0.0247 0.0876 0.0869
Loa Loa (eye worm) acetyltransferase 0.0148 0.0486 0.0478
Brugia malayi MH2 domain containing protein 0.0362 0.133 0.1322
Brugia malayi follicle stimulating hormone receptor 0.0129 0.0412 0.0402
Schistosoma mansoni thyroid hormone receptor 0.0164 0.055 0.0991
Schistosoma mansoni thyroid hormone receptor 0.0164 0.055 0.0991
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.0266 0.0469
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0129 0.0412 0.0736
Echinococcus multilocularis small conductance calcium activated potassium 0.0798 0.3056 0.5583
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0129 0.0412 0.0736
Loa Loa (eye worm) hypothetical protein 0.0088 0.025 0.0242
Onchocerca volvulus 0.0088 0.025 0.442
Schistosoma mansoni ap endonuclease 0.0037 0.0048 0.0069
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0464 0.1734 1
Trypanosoma brucei protein kinase, putative 0.0052 0.0107 0.0107
Onchocerca volvulus 0.0073 0.0188 0.3283
Echinococcus multilocularis neuropeptide receptor 0.0129 0.0412 0.0736
Onchocerca volvulus 0.0129 0.0412 0.7395
Schistosoma mansoni biogenic amine (5HT) receptor 0.0129 0.0412 0.0736
Loa Loa (eye worm) hypothetical protein 0.0036 0.0044 0.0036
Loa Loa (eye worm) hypothetical protein 0.0073 0.0188 0.018
Echinococcus multilocularis beta LACTamase domain containing family member 0.0073 0.0188 0.0327
Loa Loa (eye worm) hypothetical protein 0.0036 0.0044 0.0036
Loa Loa (eye worm) hypothetical protein 0.0129 0.0412 0.0404
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0053 0.0112 0.0102
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0037 0.0048 0.0048
Onchocerca volvulus 0.0129 0.0412 0.7395
Echinococcus granulosus fmrfamide receptor 0.0129 0.0412 0.0736
Loa Loa (eye worm) hypothetical protein 0.0129 0.0412 0.0404
Loa Loa (eye worm) hypothetical protein 0.0129 0.0412 0.0404
Loa Loa (eye worm) hypothetical protein 0.0036 0.0044 0.0036
Loa Loa (eye worm) hypothetical protein 0.0129 0.0412 0.0404
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0129 0.0412 0.0736
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0129 0.0412 0.0736
Onchocerca volvulus 0.0129 0.0412 0.7395
Loa Loa (eye worm) carboxylesterase 0.0066 0.0163 0.0155
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0088 0.025 0.044
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0129 0.0412 0.7395
Loa Loa (eye worm) hypothetical protein 0.0372 0.1371 0.1364
Treponema pallidum nitrogen fixation protein (rnfC) 0.0042 0.0069 0.2752
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0553 0.5305
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0043 0.0073 0.3888
Echinococcus granulosus rhodopsin orphan GPCR 0.0129 0.0412 0.0736
Echinococcus multilocularis neuropeptide receptor 0.0129 0.0412 0.0736
Loa Loa (eye worm) hypothetical protein 0.0129 0.0412 0.0404
Entamoeba histolytica acetyltransferase, GNAT family 0.004 0.0059 0.0456
Schistosoma mansoni hypothetical protein 0.0038 0.0053 0.0079
Trichomonas vaginalis bromodomain-containing protein, putative 0.0043 0.0073 0.0302
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 21 0.0036 0.0044 0.0034
Loa Loa (eye worm) beta-lactamase 0.0073 0.0188 0.018
Leishmania major hypothetical protein, conserved 0.0036 0.0044 0.0044
Onchocerca volvulus 0.0129 0.0412 0.7395
Loa Loa (eye worm) TWK-7 protein 0.0036 0.0044 0.0036
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0129 0.0412 0.0402
Echinococcus granulosus tm gpcr rhodopsin 0.0129 0.0412 0.0736
Toxoplasma gondii exonuclease III APE 0.0037 0.0048 0.2528
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0129 0.0412 0.0402
Loa Loa (eye worm) hypothetical protein 0.0036 0.0044 0.0036
Loa Loa (eye worm) hypothetical protein 0.0131 0.0418 0.041
Echinococcus multilocularis serotonin receptor 0.0247 0.0876 0.1588
Brugia malayi ORL1-like opioid receptor 0.0129 0.0412 0.0402
Giardia lamblia Kinase, CMGC MAPK 0.0052 0.0107 0.0501
Loa Loa (eye worm) hypothetical protein 0.0129 0.0412 0.0404
Brugia malayi hypothetical protein 0.0129 0.0412 0.0402
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0129 0.0412 0.0404
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0129 0.0412 0.0736
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 19. C. elegans unc-58 ortholog 0.0036 0.0044 0.0034
Echinococcus multilocularis twik family of potassium channels 0.0036 0.0044 0.0063
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.0266 0.0469
Entamoeba histolytica hypothetical protein 0.0038 0.0053 0.0411
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0037 0.0048 0.0369
Echinococcus granulosus orexin receptor type 2 0.0129 0.0412 0.0736
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0129 0.0412 0.0736
Loa Loa (eye worm) hypothetical protein 0.0129 0.0412 0.0404
Loa Loa (eye worm) hypothetical protein 0.0129 0.0412 0.0404
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 38. C. elegans sup-9 ortholog 0.0036 0.0044 0.0034
Onchocerca volvulus 0.0036 0.0044 0.063
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0129 0.0412 0.0736
Echinococcus granulosus dro:myosuppressin receptor 0.0129 0.0412 0.0736
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0129 0.0412 0.0736
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0073 0.0188 0.0327
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0028 0.001 0.0002
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 7 0.0036 0.0044 0.0034
Loa Loa (eye worm) TWK-28 protein 0.0036 0.0044 0.0036
Loa Loa (eye worm) hypothetical protein 0.0129 0.0412 0.0404
Loa Loa (eye worm) TYRA-2 protein 0.0129 0.0412 0.0404
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0129 0.0412 0.0736
Loa Loa (eye worm) hypothetical protein 0.0036 0.0044 0.0036
Echinococcus multilocularis NADH dehydrogenase (ubiquinone) flavoprotein 1 0.019 0.0653 0.1178
Onchocerca volvulus 0.0129 0.0412 0.7395
Brugia malayi beta-lactamase family protein 0.0073 0.0188 0.0178
Echinococcus granulosus somatostatin receptor 0.0129 0.0412 0.0736
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 12 0.0036 0.0044 0.0034
Echinococcus granulosus serotonin receptor 0.0129 0.0412 0.0736
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0129 0.0412 0.0736
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0052 0.0107 0.0107
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0073 0.0188 0.1086
Schistosoma mansoni serine/threonine protein kinase 0.0052 0.0107 0.0177
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0052 0.0107 0.0063
Loa Loa (eye worm) hypothetical protein 0.0129 0.0412 0.0404
Loa Loa (eye worm) hypothetical protein 0.0129 0.0412 0.0404
Mycobacterium leprae Probable lipase LipE 0.0073 0.0188 1
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0043 0.0073 0.3888
Schistosoma mansoni opsin-like receptor 0.0129 0.0412 0.0736
Mycobacterium tuberculosis Conserved protein 0.0073 0.0188 0.1086
Echinococcus granulosus small conductance calcium activated potassium 0.0798 0.3056 0.5583
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0553 0.5305
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0037 0.0048 0.0003
Loa Loa (eye worm) hypothetical protein 0.0036 0.0044 0.0036
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0129 0.0412 0.0736
Trichomonas vaginalis ap endonuclease, putative 0.0037 0.0048 0.0035
Trypanosoma cruzi NADH-ubiquinone oxidoreductase, mitochondrial, putative 0.019 0.0653 0.0611
Trichomonas vaginalis glutaminase, putative 0.0279 0.1003 1
Loa Loa (eye worm) hypothetical protein 0.0129 0.0412 0.0404
Leishmania major C-8 sterol isomerase-like protein 0.2555 1 1
Schistosoma mansoni neuropeptide f receptor 76f 0.0129 0.0412 0.0736
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 45 0.0036 0.0044 0.0034
Schistosoma mansoni opsin-like receptor 0.0129 0.0412 0.0736
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0129 0.0412 0.0736
Trypanosoma cruzi NADH-ubiquinone oxidoreductase, mitochondrial, putative 0.019 0.0653 0.0611
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.0895 0.8866
Schistosoma mansoni biogenic amine receptor 0.0129 0.0412 0.0736
Brugia malayi hypothetical protein 0.0129 0.0412 0.0402
Loa Loa (eye worm) hypothetical protein 0.0131 0.0418 0.041
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0073 0.0188 0.018
Loa Loa (eye worm) hypothetical protein 0.0036 0.0044 0.0036
Echinococcus granulosus g protein coupled receptor 0.0129 0.0412 0.0736
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0092 0.0266 0.0256
Loa Loa (eye worm) hypothetical protein 0.0129 0.0412 0.0404
Loa Loa (eye worm) hypothetical protein 0.0036 0.0044 0.0036
Loa Loa (eye worm) S-phase kinase-associated protein 1A 0.0036 0.0044 0.0036
Trichomonas vaginalis ap endonuclease, putative 0.0037 0.0048 0.0035
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0043 0.0073 0.3888
Plasmodium falciparum histone acetyltransferase GCN5 0.004 0.0059 1
Leishmania major potassium channel subunit-like protein 0.0036 0.0044 0.0044
Echinococcus granulosus g protein coupled receptor 0.0129 0.0412 0.0736
Loa Loa (eye worm) acetylcholinesterase 1 0.0066 0.0163 0.0155
Loa Loa (eye worm) hypothetical protein 0.0036 0.0044 0.0036
Schistosoma mansoni ap endonuclease 0.0037 0.0048 0.0069
Wolbachia endosymbiont of Brugia malayi NADH dehydrogenase I subunit F 0.019 0.0653 1
Echinococcus multilocularis G protein coupled receptor 139 0.0129 0.0412 0.0736
Brugia malayi hypothetical protein 0.0036 0.0044 0.0034
Echinococcus granulosus acetylcholinesterase 0.0066 0.0163 0.0281
Echinococcus granulosus rhodopsin orphan GPCR 0.0129 0.0412 0.0736
Echinococcus granulosus rhodopsin orphan GPCR 0.0129 0.0412 0.0736
Loa Loa (eye worm) hypothetical protein 0.0036 0.0044 0.0036
Echinococcus granulosus rhodopsin orphan GPCR 0.0129 0.0412 0.0736
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0037 0.0048 0.0475
Schistosoma mansoni neuropeptide receptor 0.0129 0.0412 0.0736
Onchocerca volvulus 0.0129 0.0412 0.7395
Trichomonas vaginalis NADH-ubiquinone oxidoreductase flavoprotein, putative 0.019 0.0653 0.6343
Trypanosoma brucei NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial, putative 0.019 0.0653 0.0653
Treponema pallidum sodium- and chloride- dependent transporter 0.0088 0.025 1
Toxoplasma gondii ion channel protein 0.0036 0.0044 0.2352
Echinococcus granulosus rhodopsin orphan GPCR 0.0129 0.0412 0.0736
Loa Loa (eye worm) hypothetical protein 0.0036 0.0044 0.0036
Loa Loa (eye worm) hypothetical protein 0.0036 0.0044 0.0036
Onchocerca volvulus 0.0129 0.0412 0.7395
Brugia malayi Dopamine receptor 0.0129 0.0412 0.0402
Onchocerca volvulus 0.0036 0.0044 0.063
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.0188 0.1502
Loa Loa (eye worm) hypothetical protein 0.0036 0.0044 0.0036
Echinococcus multilocularis neuropeptide Y receptor 0.0129 0.0412 0.0736
Schistosoma mansoni twik family of potassium channels-related 0.0036 0.0044 0.0063
Loa Loa (eye worm) hypothetical protein 0.0129 0.0412 0.0404
Schistosoma mansoni adenoreceptor 0.0129 0.0412 0.0736
Loa Loa (eye worm) hypothetical protein 0.0036 0.0044 0.0036
Echinococcus granulosus microtubule associated protein 2 0.1408 0.5465 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0092 0.0266 0.0469
Loa Loa (eye worm) large conductance calcium-activated potassium channel alpha subunit ai 0.0036 0.0044 0.0036
Loa Loa (eye worm) hypothetical protein 0.0129 0.0412 0.0404
Onchocerca volvulus 0.0129 0.0412 0.7395
Onchocerca volvulus Glucosylceramidase homolog 0.0165 0.0553 1
Brugia malayi Dopamine receptor protein 1 0.0129 0.0412 0.0402
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0037 0.0048 0.0048
Echinococcus multilocularis TWiK family of potassium channels protein 7 0.0036 0.0044 0.0063
Echinococcus multilocularis rhodopsin orphan GPCR 0.0129 0.0412 0.0736
Brugia malayi Calcitonin receptor-like protein seb-1 0.0053 0.0112 0.0102
Schistosoma mansoni hypothetical protein 0.0129 0.0412 0.0736
Loa Loa (eye worm) hypothetical protein 0.0129 0.0412 0.0404
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0089 0.0252 0.0242
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0553 0.5305
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0129 0.0412 0.0736
Toxoplasma gondii ABC1 family protein 0.0073 0.0188 1
Echinococcus granulosus mitogen activated protein kinase 0.0052 0.0107 0.0177
Echinococcus granulosus neuropeptide FF receptor 2 0.0129 0.0412 0.0736
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 39A 0.0036 0.0044 0.0034
Echinococcus granulosus neuropeptide s receptor 0.0129 0.0412 0.0736
Echinococcus granulosus biogenic amine 5HT receptor 0.0247 0.0876 0.1588
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0107 0.0652
Trypanosoma brucei NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial 0.019 0.0653 0.0653
Echinococcus multilocularis rhodopsin orphan GPCR 0.0129 0.0412 0.0736
Schistosoma mansoni amine GPCR 0.0129 0.0412 0.0736
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0052 0.0107 0.0063
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0553 0.5305
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0107 0.0652
Echinococcus granulosus potassium channel subfamily K 8 0.0036 0.0044 0.0063
Echinococcus granulosus biogenic amine 5HT receptor 0.0129 0.0412 0.0736
Schistosoma mansoni hypothetical protein 0.0129 0.0412 0.0736
Echinococcus granulosus rhodopsin orphan GPCR 0.0129 0.0412 0.0736
Giardia lamblia DNA repair protein RAD52 0.0352 0.1292 1
Brugia malayi neuropeptide F receptor 0.0129 0.0412 0.0402
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0037 0.0048 0.0274
Echinococcus multilocularis g protein coupled receptor 0.0129 0.0412 0.0736
Schistosoma mansoni hypothetical protein 0.0152 0.0502 0.0902
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.0895 0.8866
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0092 0.0266 0.0469
Loa Loa (eye worm) potassium voltage-gated channel subfamily Q member 5 0.0036 0.0044 0.0036
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0129 0.0412 0.0736
Loa Loa (eye worm) hypothetical protein 0.0036 0.0044 0.0036
Brugia malayi G-protein coupled receptor 0.0129 0.0412 0.0402
Onchocerca volvulus NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial homolog 0.0102 0.0304 0.5414
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0129 0.0412 0.0736
Onchocerca volvulus 0.0129 0.0412 0.7395
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0073 0.0188 0.0178
Echinococcus granulosus neuropeptide receptor 0.0129 0.0412 0.0736
Loa Loa (eye worm) hypothetical protein 0.0129 0.0412 0.0404
Loa Loa (eye worm) hypothetical protein 0.0129 0.0412 0.0404
Loa Loa (eye worm) hypothetical protein 0.0036 0.0044 0.0036
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 39B 0.0036 0.0044 0.0034
Schistosoma mansoni hypothetical protein 0.0036 0.0044 0.0063
Echinococcus granulosus neuropeptide Y receptor 0.0129 0.0412 0.0736
Echinococcus multilocularis potassium channel subfamily K 8 0.0036 0.0044 0.0063
Echinococcus granulosus mitogen activated protein kinase 3 0.0052 0.0107 0.0177
Loa Loa (eye worm) hypothetical protein 0.0129 0.0412 0.0404
Brugia malayi larval opioid receptor 0.0129 0.0412 0.0402
Loa Loa (eye worm) hypothetical protein 0.0036 0.0044 0.0036
Schistosoma mansoni hypothetical protein 0.0678 0.2581 0.4714
Brugia malayi MAP kinase sur-1 0.0052 0.0107 0.0097
Echinococcus multilocularis sex peptide receptor 0.0129 0.0412 0.0736
Brugia malayi putative neuropeptide receptor NPR1 0.0129 0.0412 0.0402
Schistosoma mansoni calcium-activated potassium channel 0.0036 0.0044 0.0063
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.0266 0.0469
Loa Loa (eye worm) hypothetical protein 0.0084 0.0234 0.0226
Echinococcus multilocularis fmrfamide receptor 0.0129 0.0412 0.0736
Brugia malayi RE15519p 0.0129 0.0412 0.0402
Loa Loa (eye worm) hypothetical protein 0.0036 0.0044 0.0036
Trypanosoma brucei calcium-activated potassium channel, putative 0.0036 0.0044 0.0044
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0066 0.0163 0.0281
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.0188 0.1502
Loa Loa (eye worm) hypothetical protein 0.0036 0.0044 0.0036
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 5 0.0036 0.0044 0.0034
Schistosoma mansoni hypothetical protein 0.0798 0.3056 0.5583
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0129 0.0412 0.0736
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0092 0.0266 0.0469
Schistosoma mansoni opsin-like receptor 0.0129 0.0412 0.0736
Echinococcus multilocularis acetylcholinesterase 0.0066 0.0163 0.0281
Loa Loa (eye worm) hypothetical protein 0.0053 0.0112 0.0104
Schistosoma mansoni twik family of potassium channels-related 0.0036 0.0044 0.0063
Schistosoma mansoni biogenic amine receptor 0.0129 0.0412 0.0736
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0129 0.0412 0.0736
Echinococcus multilocularis G-protein coupled receptor, putative 0.0129 0.0412 0.0736
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 13 0.0036 0.0044 0.0034
Loa Loa (eye worm) hypothetical protein 0.0036 0.0044 0.0036
Schistosoma mansoni glutaminase 0.0279 0.1003 0.1821
Loa Loa (eye worm) hypothetical protein 0.0129 0.0412 0.0404
Loa Loa (eye worm) hypothetical protein 0.0129 0.0412 0.0404
Schistosoma mansoni amine GPCR 0.0129 0.0412 0.0736
Trypanosoma brucei hypothetical protein, conserved 0.0073 0.0188 0.0188
Echinococcus granulosus neuropeptides capa receptor 0.0129 0.0412 0.0736
Mycobacterium tuberculosis Probable lipase LipE 0.0073 0.0188 0.1086
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0073 0.0188 0.1086
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0129 0.0412 0.0736
Mycobacterium ulcerans beta-lactamase 0.0073 0.0188 0.1877
Loa Loa (eye worm) hypothetical protein 0.0089 0.0252 0.0244
Plasmodium vivax hypothetical protein, conserved 0.0073 0.0188 1
Brugia malayi beta-lactamase 0.0073 0.0188 0.0178
Brugia malayi putative neuropeptide receptor 0.0129 0.0412 0.0402
Brugia malayi G protein-coupled receptor F59B2.13 0.0129 0.0412 0.0402
Mycobacterium ulcerans transmembrane cation transporter 0.0036 0.0044 0.0441
Loa Loa (eye worm) hypothetical protein 0.0129 0.0412 0.0404
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0073 0.0188 0.1086
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0129 0.0412 0.0736
Loa Loa (eye worm) hypothetical protein 0.0129 0.0412 0.0404
Onchocerca volvulus 0.0129 0.0412 0.7395
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.0188 0.1502
Echinococcus granulosus rhodopsin orphan GPCR 0.0129 0.0412 0.0736
Brugia malayi Melatonin receptor type 1A 0.0129 0.0412 0.0402
Onchocerca volvulus 0.0129 0.0412 0.7395
Schistosoma mansoni twik family of potassium channels-related 0.0036 0.0044 0.0063
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0129 0.0412 0.0736
Schistosoma mansoni neuropeptide F-like receptor 0.0129 0.0412 0.0736
Toxoplasma gondii ion channel protein 0.0036 0.0044 0.2352
Schistosoma mansoni twik family of potassium channels-related 0.0036 0.0044 0.0063
Loa Loa (eye worm) glutaminase 2 0.0279 0.1003 0.0996
Trichomonas vaginalis penicillin-binding protein, putative 0.0073 0.0188 0.1502
Echinococcus multilocularis rhodopsin orphan GPCR 0.0129 0.0412 0.0736
Echinococcus multilocularis g protein coupled receptor 0.0129 0.0412 0.0736
Mycobacterium ulcerans membrane protein ComEA 0.0042 0.0069 0.0686
Onchocerca volvulus 0.0129 0.0412 0.7395
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0052 0.0107 0.0107
Echinococcus granulosus acetylcholinesterase 0.0066 0.0163 0.0281
Loa Loa (eye worm) neuropeptide F receptor 0.0129 0.0412 0.0404
Loa Loa (eye worm) hypothetical protein 0.0129 0.0412 0.0404
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0129 0.0412 0.0736
Echinococcus multilocularis rhodopsin orphan GPCR 0.0129 0.0412 0.0736
Mycobacterium tuberculosis Conserved hypothetical protein 0.0042 0.0069 0.0397
Mycobacterium tuberculosis Probable hydrolase 0.0073 0.0188 0.1086
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0053 0.0112 0.0104
Entamoeba histolytica hypothetical protein 0.01 0.0297 0.2299
Schistosoma mansoni alpha-1 adrenergic receptor 0.0129 0.0412 0.0736
Loa Loa (eye worm) uncoordinated protein 58 0.0036 0.0044 0.0036
Brugia malayi Carboxylesterase family protein 0.0066 0.0163 0.0153
Echinococcus granulosus beta LACTamase domain containing family member 0.0073 0.0188 0.0327
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0129 0.0412 0.0736
Loa Loa (eye worm) hypothetical protein 0.0036 0.0044 0.0036
Echinococcus granulosus serotonin transporter 0.0088 0.025 0.044
Echinococcus granulosus g-protein coupled receptor 0.0129 0.0412 0.0736
Treponema pallidum exodeoxyribonuclease (exoA) 0.0037 0.0048 0.1904
Echinococcus granulosus potassium channel subfamily K 8 0.0036 0.0044 0.0063
Schistosoma mansoni amine GPCR 0.0129 0.0412 0.0736
Loa Loa (eye worm) NADH-ubiquinone oxidoreductase 51 kDa subunit 0.019 0.0653 0.0645
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0052 0.0107 0.0063
Brugia malayi sulfakinin receptor protein 0.0129 0.0412 0.0402
Mycobacterium tuberculosis Probable esterase LipL 0.0073 0.0188 0.1086
Mycobacterium tuberculosis Conserved protein 0.0073 0.0188 0.1086
Brugia malayi hypothetical protein 0.0129 0.0412 0.0402
Loa Loa (eye worm) hypothetical protein 0.0129 0.0412 0.0404
Schistosoma mansoni neuropeptide receptor 0.0129 0.0412 0.0736
Brugia malayi hypothetical protein 0.0129 0.0412 0.0402
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0148 0.0486 0.0872
Entamoeba histolytica hypothetical protein 0.0038 0.0053 0.0411
Echinococcus granulosus neuropeptide receptor 0.0129 0.0412 0.0736
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0129 0.0412 0.0736
Echinococcus granulosus neuropeptide Y receptor 0.0129 0.0412 0.0736
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.0895 0.8866
Loa Loa (eye worm) hypothetical protein 0.0036 0.0044 0.0036
Loa Loa (eye worm) hypothetical protein 0.0129 0.0412 0.0404
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0152 0.0502 0.0902
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.0895 0.8866
Echinococcus granulosus NADH dehydrogenase ubiquinone flavoprotein 1 0.019 0.0653 0.1178
Mycobacterium leprae conserved hypothetical protein 0.0073 0.0188 1
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0129 0.0412 0.0736
Brugia malayi Serotonin receptor 0.0129 0.0412 0.0402
Giardia lamblia Histone acetyltransferase GCN5 0.004 0.0059 0.0117

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.