Detailed information for compound 915390

Basic information

Technical information
  • TDR Targets ID: 915390
  • Name: 5-[[3-(furan-2-carbonylamino)-5-[(6-sulfonaph thalen-1-yl)carbamoyl]benzoyl]amino]naphthale ne-2-sulfonic acid
  • MW: 685.68 | Formula: C33H23N3O10S2
  • H donors: 5 H acceptors: 9 LogP: 3.82 Rotable bonds: 11
    Rule of 5 violations (Lipinski): 2
  • SMILES: O=C(c1cc(NC(=O)c2ccco2)cc(c1)C(=O)Nc1cccc2c1ccc(c2)S(=O)(=O)O)Nc1cccc2c1ccc(c2)S(=O)(=O)O
  • InChi: 1S/C33H23N3O10S2/c37-31(35-28-6-1-4-19-17-24(47(40,41)42)9-11-26(19)28)21-14-22(16-23(15-21)34-33(39)30-8-3-13-46-30)32(38)36-29-7-2-5-20-18-25(48(43,44)45)10-12-27(20)29/h1-18H,(H,34,39)(H,35,37)(H,36,38)(H,40,41,42)(H,43,44,45)
  • InChiKey: GFTSGGTXPHFCMQ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 5-[[3-(furan-2-carbonylamino)-5-[(6-sulfo-1-naphthyl)carbamoyl]benzoyl]amino]naphthalene-2-sulfonic acid
  • 5-[[[3-[(2-furyl-oxomethyl)amino]-5-[oxo-[(6-sulfo-1-naphthyl)amino]methyl]phenyl]-oxomethyl]amino]-2-naphthalenesulfonic acid
  • 5-[[3-(furan-2-ylcarbonylamino)-5-[(6-sulfonaphthalen-1-yl)carbamoyl]phenyl]carbonylamino]naphthalene-2-sulfonic acid

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis orexin receptor type 2 0.0015 0.0223 0.0347
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0024 0.0538 0.0845
Leishmania major cytochrome p450-like protein 0.0013 0.0134 0.0103
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.1149 0.1121
Echinococcus granulosus heat shock protein 67b2 0.001 0.0032 0.0045
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0015 0.0223 0.0566
Echinococcus granulosus neuropeptides capa receptor 0.0015 0.0223 0.0347
Echinococcus granulosus neuropeptide Y receptor 0.0015 0.0223 0.0347
Brugia malayi Immunoglobulin I-set domain containing protein 0.0015 0.0208 0.0527
Brugia malayi orphan nuclear receptor NR2E1 0.0012 0.0096 0.0243
Loa Loa (eye worm) CYP4Cod1 0.0013 0.0134 0.0332
Echinococcus multilocularis fmrfamide receptor 0.0015 0.0223 0.0347
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.1149 0.1121
Schistosoma mansoni hypothetical protein 0.0175 0.5673 0.5705
Schistosoma mansoni opsin-like receptor 0.0015 0.0223 0.0193
Echinococcus granulosus FTZ F1 alpha 0.0024 0.0538 0.0845
Brugia malayi putative neuropeptide receptor 0.0015 0.0223 0.0566
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0223 0.0347
Echinococcus multilocularis G protein coupled receptor 139 0.0015 0.0223 0.0347
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0015 0.0223 0.0347
Schistosoma mansoni biogenic amine receptor 0.0015 0.0223 0.0193
Echinococcus multilocularis neuropeptide Y receptor 0.0015 0.0223 0.0347
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0301 1 1
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0015 0.0223 0.0347
Schistosoma mansoni growth hormone secretagogue receptor 0.0015 0.0223 0.0193
Echinococcus multilocularis dro:myosuppressin receptor 0.0015 0.0223 0.0347
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0223 0.0347
Schistosoma mansoni neuropeptide receptor 0.0015 0.0223 0.0193
Echinococcus granulosus serotonin receptor 0.0015 0.0223 0.0347
Loa Loa (eye worm) hypothetical protein 0.0012 0.0096 0.0233
Brugia malayi MoeZ/MoeB domain containing protein 0.001 0.0032 0.0081
Brugia malayi Serotonin receptor 0.0015 0.0223 0.0566
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0015 0.0208 0.0517
Schistosoma mansoni neuropeptide receptor 0.0015 0.0223 0.0193
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0024 0.0538 0.1365
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0223 0.0193
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0223 0.0193
Onchocerca volvulus 0.0015 0.0223 0.0489
Brugia malayi Rhodanese-like domain containing protein 0.001 0.0032 0.0081
Schistosoma mansoni hypothetical protein 0.008 0.2427 0.2422
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0013 0.0134 0.0201
Giardia lamblia Hypothetical protein 0.001 0.0032 0.5
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0024 0.0538 0.1357
Trichomonas vaginalis mitotic inducer phosphatase CDC25, putative 0.0124 0.394 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0015 0.0223 0.0347
Onchocerca volvulus 0.0015 0.0223 0.0489
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0015 0.0223 0.0566
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0015 0.0223 0.0347
Loa Loa (eye worm) hypothetical protein 0.0013 0.0143 0.0354
Echinococcus granulosus hypothetical protein 0.0015 0.0223 0.0347
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0056 0.1615 0.4098
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0015 0.0223 0.0347
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0142 0.4575 0.4558
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0012 0.0096 0.0145
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0024 0.0538 0.0512
Loa Loa (eye worm) hypothetical protein 0.0114 0.3609 0.9159
Schistosoma mansoni nuclear hormone receptor 0.0024 0.0538 0.0512
Schistosoma mansoni histamine h1 receptor 0.0015 0.0223 0.0193
Chlamydia trachomatis hypothetical protein 0.001 0.0032 0.5
Loa Loa (eye worm) hypothetical protein 0.0015 0.0223 0.0557
Loa Loa (eye worm) hypothetical protein 0.0015 0.0223 0.0557
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0013 0.0143 0.022
Onchocerca volvulus 0.0015 0.0223 0.0489
Schistosoma mansoni m-phase inducer phosphatase(cdc25) 0.0124 0.394 0.3953
Loa Loa (eye worm) TYRA-2 protein 0.0015 0.0223 0.0557
Loa Loa (eye worm) hypothetical protein 0.0015 0.0223 0.0557
Echinococcus granulosus Nuclear hormone receptor HR96 0.0012 0.0096 0.0145
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0223 0.0193
Schistosoma mansoni ankyrin 23/unc44 0.0015 0.0208 0.0178
Echinococcus granulosus 7tm_1 domain containing protein 0.0015 0.0223 0.0347
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0223 0.0347
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0223 0.0193
Schistosoma mansoni neuropeptide f receptor 76f 0.0015 0.0223 0.0193
Onchocerca volvulus 0.0015 0.0223 0.0489
Schistosoma mansoni nuclear hormone receptor 0.0012 0.0096 0.0064
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0223 0.0347
Loa Loa (eye worm) hypothetical protein 0.0015 0.0223 0.0557
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.1778 0.1766
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0015 0.0212 0.0182
Loa Loa (eye worm) hypothetical protein 0.001 0.0032 0.0071
Echinococcus multilocularis heat shock protein 67b2 0.001 0.0032 0.0045
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0223 0.0347
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0223 0.0347
Loa Loa (eye worm) hypothetical protein 0.0015 0.0223 0.0557
Loa Loa (eye worm) hypothetical protein 0.0124 0.394 1
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0024 0.0538 0.0512
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0223 0.0193
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0098 0.3055 0.4827
Echinococcus multilocularis g protein coupled receptor 0.0015 0.0223 0.0347
Loa Loa (eye worm) neuropeptide F receptor 0.0015 0.0223 0.0557
Echinococcus multilocularis sex peptide receptor 0.0015 0.0223 0.0347
Schistosoma mansoni netrin receptor unc5 0.0015 0.0208 0.0178
Echinococcus granulosus Rhodanese 0.001 0.0032 0.0045
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0024 0.0538 0.1365
Echinococcus multilocularis fmrfamide receptor 0.0015 0.0223 0.0347
Schistosoma mansoni myosin xvIII 0.0015 0.0223 0.0193
Echinococcus granulosus geminin 0.0175 0.5673 0.8968
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0223 0.0347
Loa Loa (eye worm) hypothetical protein 0.0015 0.0208 0.0517
Onchocerca volvulus 0.0012 0.0096 0.0163
Brugia malayi conserved hypotetical protein 0.0012 0.0096 0.0243
Echinococcus multilocularis centrosomal protein of 41 kDa 0.001 0.0032 0.0045
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0049 0.1382 0.1365
Echinococcus granulosus g protein coupled receptor 0.0015 0.0223 0.0347
Onchocerca volvulus Protein ultraspiracle homolog 0.0024 0.0538 0.1294
Loa Loa (eye worm) neuropeptide F receptor 0.0015 0.0223 0.0557
Giardia lamblia Hypothetical protein 0.001 0.0032 0.5
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0015 0.0223 0.0347
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0015 0.0223 0.0347
Echinococcus granulosus neuropeptide s receptor 0.0015 0.0223 0.0347
Giardia lamblia Dual specificity phosphatase Cdc25, putative 0.001 0.0032 0.5
Echinococcus granulosus tm gpcr rhodopsin 0.0015 0.0223 0.0347
Schistosoma mansoni sex comb on midleg homolog 0.0049 0.1382 0.1365
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0015 0.0223 0.0193
Echinococcus multilocularis Ankyrin 0.0015 0.0212 0.0329
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0223 0.0347
Brugia malayi Dopamine receptor protein 1 0.0015 0.0223 0.0566
Echinococcus granulosus allatostatin A receptor 0.0015 0.0223 0.0347
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0015 0.0223 0.0566
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0012 0.0096 0.0145
Brugia malayi nuclear receptor NHR-88 0.0012 0.0096 0.0243
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0015 0.0223 0.0557
Loa Loa (eye worm) hypothetical protein 0.0095 0.2963 0.7517
Brugia malayi Dopamine receptor 0.0015 0.0223 0.0566
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0015 0.0223 0.0557
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0024 0.0538 0.0512
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0042 0.1149 0.1121
Loa Loa (eye worm) hypothetical protein 0.0015 0.0223 0.0557
Brugia malayi steroid hormone receptor 0.0024 0.0538 0.1365
Loa Loa (eye worm) hypothetical protein 0.0024 0.0538 0.1357
Loa Loa (eye worm) hypothetical protein 0.0015 0.0223 0.0557
Schistosoma mansoni hypothetical protein 0.0175 0.5673 0.5705
Loa Loa (eye worm) hypothetical protein 0.0012 0.0096 0.0233
Brugia malayi Nuclear hormone receptor-like 1 0.0024 0.0538 0.1365
Loa Loa (eye worm) hypothetical protein 0.0015 0.0223 0.0557
Echinococcus granulosus polycomb protein SCMH1 0.0049 0.1382 0.218
Echinococcus multilocularis geminin 0.0175 0.5673 0.8968
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0015 0.0223 0.0193
Loa Loa (eye worm) hypothetical protein 0.0024 0.0538 0.1357
Mycobacterium leprae Probable thiosulfate sulfurtransferase SseA (RHODANESE) (THIOSULFATE CYANIDE TRANSSULFURASE) (THIOSULFATE THIOTRANSFERASE) 0.001 0.0032 0.5
Loa Loa (eye worm) hypothetical protein 0.0015 0.0223 0.0557
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0024 0.0538 0.1294
Brugia malayi GnHR receptor homolog 0.0015 0.0223 0.0566
Loa Loa (eye worm) nuclear hormone receptor 0.0012 0.0096 0.0233
Brugia malayi ecdysone receptor 0.0012 0.0096 0.0243
Echinococcus multilocularis tRNA 2 selenouridine synthase 0.001 0.0032 0.0045
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0223 0.0347
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0024 0.0538 0.1365
Echinococcus multilocularis serotonin receptor 0.0015 0.0223 0.0347
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0024 0.0538 0.1365
Schistosoma mansoni biogenic amine receptor 0.0015 0.0223 0.0193
Onchocerca volvulus 0.0015 0.0223 0.0489
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0024 0.0538 0.0845
Loa Loa (eye worm) hypothetical protein 0.0015 0.0223 0.0557
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0024 0.0538 0.1357
Schistosoma mansoni zinc finger protein 0.0012 0.0096 0.0064
Loa Loa (eye worm) hypothetical protein 0.0015 0.0223 0.0557
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0024 0.0538 0.0845
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0098 0.3055 0.4827
Schistosoma mansoni biogenic amine receptor 0.0015 0.0223 0.0193
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0015 0.0223 0.0347
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0024 0.0538 0.1357
Echinococcus granulosus tm gpcr rhodopsin 0.0015 0.0223 0.0347
Echinococcus multilocularis neuropeptide FF receptor 2 0.0015 0.0223 0.0347
Trypanosoma brucei cytochrome P450, putative 0.0013 0.0134 0.0103
Loa Loa (eye worm) hypothetical protein 0.0024 0.0538 0.1357
Schistosoma mansoni hypothetical protein 0.0015 0.0223 0.0193
Loa Loa (eye worm) hypothetical protein 0.0015 0.0223 0.0557
Brugia malayi hypothetical protein 0.0013 0.0143 0.0363
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0015 0.0223 0.0193
Schistosoma mansoni jun-related protein 0.008 0.2427 0.2422
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0076 0.2296 0.3626
Schistosoma mansoni cpg binding protein 0.003 0.0736 0.0712
Brugia malayi hypothetical protein 0.0012 0.0096 0.0243
Loa Loa (eye worm) G-protein coupled receptor 0.0015 0.0223 0.0557
Onchocerca volvulus 0.0015 0.0223 0.0489
Onchocerca volvulus 0.0049 0.1382 0.3454
Onchocerca volvulus 0.0024 0.0538 0.1294
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0015 0.0223 0.0347
Brugia malayi Dopamine receptor protein 2 0.0015 0.0223 0.0566
Brugia malayi Serotonin receptor 0.0015 0.0223 0.0566
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0012 0.0096 0.0243
Loa Loa (eye worm) hypothetical protein 0.0056 0.1615 0.4092
Schistosoma mansoni cpg binding protein 0.0029 0.068 0.0656
Schistosoma mansoni sex comb on midleg homolog 0.0049 0.1382 0.1365
Echinococcus granulosus neuropeptide Y receptor 0.0015 0.0223 0.0347
Trichomonas vaginalis mitotic inducer phosphatase CDC25, putative 0.0124 0.394 1
Brugia malayi hypothetical protein 0.0015 0.0223 0.0566
Loa Loa (eye worm) hypothetical protein 0.0015 0.0223 0.0557
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0223 0.0193
Onchocerca volvulus Neuropeptide F receptor homolog 0.0015 0.0223 0.0489
Onchocerca volvulus 0.0124 0.394 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0012 0.0096 0.0145
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0024 0.0538 0.0845
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0024 0.0538 0.1365
Mycobacterium leprae PROBABLE MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN MOEB1 (MPT-SYNTHASE SULFURYLASE) (MOLYBDOPTERIN SYNTHASE SULPHURYLASE) 0.001 0.0032 0.5
Loa Loa (eye worm) hypothetical protein 0.0015 0.0223 0.0557
Loa Loa (eye worm) hypothetical protein 0.0024 0.0538 0.1357
Brugia malayi Melatonin receptor type 1A 0.0015 0.0223 0.0566
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0013 0.0143 0.022
Echinococcus multilocularis m phase inducer phosphatase(cdc25) 0.0124 0.394 0.6227
Plasmodium falciparum rhodanese like protein, putative 0.001 0.0032 0.5
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0024 0.0538 0.0845
Echinococcus multilocularis neuropeptide receptor 0.0015 0.0223 0.0347
Echinococcus granulosus neuropeptide receptor 0.0015 0.0223 0.0347
Echinococcus multilocularis polycomb protein SCMH1 0.0049 0.1382 0.218
Brugia malayi nuclear hormone receptor 0.0012 0.0096 0.0243
Loa Loa (eye worm) hypothetical protein 0.0015 0.0223 0.0557
Schistosoma mansoni neuropeptide receptor 0.0015 0.0223 0.0193
Trichomonas vaginalis m-phase inducer phosphatase, putative 0.0124 0.394 1
Schistosoma mansoni hypothetical protein 0.0299 0.992 1
Brugia malayi Nuclear hormone receptor E75 0.0012 0.0096 0.0243
Schistosoma mansoni myelin transcription factor 1 myt1 0.0056 0.1615 0.16
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0015 0.0208 0.0322
Loa Loa (eye worm) hypothetical protein 0.0015 0.0223 0.0557
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0056 0.1615 0.2548
Echinococcus multilocularis neuropeptides capa receptor 0.0015 0.0223 0.0347
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0024 0.0538 0.1365
Schistosoma mansoni steroid hormone receptor ad4bp 0.0024 0.0538 0.0512
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0015 0.0223 0.0347
Brugia malayi tailless protein 0.0012 0.0096 0.0243
Echinococcus multilocularis g protein coupled receptor 0.0015 0.0223 0.0347
Schistosoma mansoni amine GPCR 0.0015 0.0223 0.0193
Schistosoma mansoni neuropeptide receptor 0.0015 0.0223 0.0193
Echinococcus granulosus 7TM GPCR rhodopsin 0.0015 0.0223 0.0347
Brugia malayi nuclear hormone receptor family member nhr-6 0.0012 0.0096 0.0243
Echinococcus granulosus nuclear factor of activated T cells 5 0.0076 0.2296 0.3626
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0012 0.0096 0.0233
Brugia malayi larval opioid receptor 0.0015 0.0223 0.0566
Loa Loa (eye worm) hypothetical protein 0.0015 0.0223 0.0557
Loa Loa (eye worm) thiosulfate sulfurtransferase 0.001 0.0032 0.0071
Echinococcus granulosus orexin receptor type 2 0.0015 0.0223 0.0347
Brugia malayi hypothetical protein 0.0013 0.0143 0.0363
Schistosoma mansoni amine GPCR 0.0015 0.0223 0.0193
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0015 0.0223 0.0193
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0194 0.6325 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0223 0.0557
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0015 0.0223 0.0557
Brugia malayi nuclear hormone receptor family member odr-7 0.0012 0.0096 0.0243
Loa Loa (eye worm) hypothetical protein 0.0015 0.0223 0.0557
Echinococcus granulosus g-protein coupled receptor 0.0015 0.0223 0.0347
Loa Loa (eye worm) hypothetical protein 0.0013 0.0143 0.0354
Loa Loa (eye worm) hypothetical protein 0.0015 0.0223 0.0557
Trypanosoma cruzi cytochrome P450, putative 0.0013 0.0134 0.0103
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0024 0.0538 0.1357
Echinococcus granulosus netrin receptor unc 5 0.0015 0.0208 0.0322
Loa Loa (eye worm) hypothetical protein 0.0012 0.0096 0.0233
Brugia malayi Cytochrome P450 family protein 0.0013 0.0134 0.0341
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0012 0.0096 0.0064
Onchocerca volvulus 0.0015 0.0223 0.0489
Schistosoma mansoni opsin-like receptor 0.0015 0.0223 0.0193
Echinococcus granulosus cpg binding protein 0.003 0.0736 0.1158
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0015 0.0223 0.0347
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0223 0.0347
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0012 0.0096 0.0163
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0024 0.0538 0.0845
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0015 0.0223 0.0347
Loa Loa (eye worm) hypothetical protein 0.0015 0.0223 0.0557
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0194 0.6325 1
Brugia malayi hypothetical protein 0.0015 0.0223 0.0566
Schistosoma mansoni neuropeptide F-like receptor 0.0015 0.0223 0.0193
Loa Loa (eye worm) hypothetical protein 0.0015 0.0223 0.0557
Trichomonas vaginalis cdc25c, putative 0.0124 0.394 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0223 0.0557
Loa Loa (eye worm) hypothetical protein 0.0015 0.0223 0.0557
Giardia lamblia Thiosulfate sulfurtransferase 0.001 0.0032 0.5
Wolbachia endosymbiont of Brugia malayi sulfurtransferase 0.001 0.0032 0.5
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0024 0.0538 0.0845
Schistosoma mansoni hypothetical protein 0.0015 0.0223 0.0193
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0024 0.0538 0.1357
Echinococcus multilocularis somatostatin receptor 0.0015 0.0223 0.0347
Echinococcus granulosus tachykinin peptides receptor 99D 0.0015 0.0223 0.0347
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0024 0.0538 0.1365
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0223 0.0193
Schistosoma mansoni thyroid hormone receptor 0.0024 0.0538 0.0512
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0012 0.0096 0.0064
Echinococcus multilocularis jun protein 0.0098 0.3055 0.4827
Loa Loa (eye worm) hypothetical protein 0.0024 0.0538 0.1357
Echinococcus granulosus g protein coupled receptor 0.0015 0.0223 0.0347
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0015 0.0223 0.0193
Brugia malayi RIKEN cDNA 4930451A13 0.001 0.0032 0.0081
Mycobacterium tuberculosis Conserved hypothetical protein 0.0159 0.5126 1
Entamoeba histolytica rodhanase-like domain containing protein 0.0124 0.394 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0223 0.0557
Echinococcus multilocularis neuropeptide Y receptor 0.0015 0.0223 0.0347
Brugia malayi hypothetical protein 0.0015 0.0223 0.0566
Loa Loa (eye worm) hypothetical protein 0.0015 0.0223 0.0557
Schistosoma mansoni amine GPCR 0.0015 0.0223 0.0193
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0024 0.0538 0.1365
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0013 0.0143 0.0112
Schistosoma mansoni nuclear receptor nhr-48 0.0012 0.0096 0.0064
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0142 0.4575 0.4558
Loa Loa (eye worm) hypothetical protein 0.0012 0.0096 0.0233
Loa Loa (eye worm) hypothetical protein 0.0012 0.0096 0.0233
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0042 0.1149 0.1121
Echinococcus multilocularis histone acetyltransferase MYST2 0.0056 0.1615 0.2548
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0015 0.0223 0.0347
Echinococcus multilocularis ecdysone induced protein 78C 0.0024 0.0538 0.0845
Brugia malayi Rhodanese-like domain containing protein 0.0124 0.394 1
Trichomonas vaginalis mitotic inducer phosphatase CDC25, putative 0.0124 0.394 1
Echinococcus granulosus neuropeptides capa receptor 0.0015 0.0223 0.0347
Echinococcus multilocularis allatostatin A receptor 0.0015 0.0223 0.0347
Mycobacterium leprae Conserved hypothetical protein 0.001 0.0032 0.5
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0015 0.0223 0.0347
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0015 0.0223 0.0347
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0223 0.0347
Schistosoma mansoni nuclear receptor 0.0012 0.0096 0.0064
Brugia malayi putative neuropeptide receptor NPR1 0.0015 0.0223 0.0566
Schistosoma mansoni biogenic amine (5HT) receptor 0.0015 0.0223 0.0193
Loa Loa (eye worm) hypothetical protein 0.0015 0.0223 0.0557
Echinococcus multilocularis neuropeptides capa receptor 0.0015 0.0223 0.0347
Loa Loa (eye worm) hypothetical protein 0.0015 0.0223 0.0557
Schistosoma mansoni hypothetical protein 0.0015 0.0223 0.0193
Loa Loa (eye worm) hypothetical protein 0.0015 0.0223 0.0557
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0015 0.0223 0.0347
Schistosoma mansoni coup transcription factor 0.0024 0.0538 0.0512
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0015 0.0223 0.0347
Brugia malayi nuclear receptor RXR 0.0013 0.0143 0.0363
Onchocerca volvulus 0.0124 0.394 1
Echinococcus multilocularis netrin receptor unc 5 0.0015 0.0208 0.0322
Onchocerca volvulus Bile acid receptor homolog 0.0024 0.0538 0.1294
Brugia malayi sulfakinin receptor protein 0.0015 0.0223 0.0566
Brugia malayi bZIP transcription factor family protein 0.0098 0.3055 0.7753
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0015 0.0223 0.0347
Loa Loa (eye worm) melatonin receptor type 1A 0.0015 0.0223 0.0557
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0024 0.0538 0.1365
Echinococcus granulosus tm gpcr rhodopsin 0.0015 0.0223 0.0347
Onchocerca volvulus 0.0015 0.0223 0.0489
Loa Loa (eye worm) hypothetical protein 0.0015 0.0223 0.0557
Loa Loa (eye worm) hypothetical protein 0.0015 0.0223 0.0557
Echinococcus granulosus sex peptide receptor 0.0015 0.0223 0.0347
Brugia malayi mbt repeat family protein 0.0049 0.1382 0.3507
Echinococcus multilocularis FTZ F1 alpha 0.0024 0.0538 0.0845
Onchocerca volvulus 0.0012 0.0096 0.0163
Echinococcus granulosus death domain containing protein 0.0015 0.0208 0.0322
Brugia malayi hypothetical protein 0.0015 0.0223 0.0566
Onchocerca volvulus 0.0077 0.2335 0.5892
Echinococcus multilocularis thyroid hormone receptor alpha 0.0024 0.0538 0.0845
Onchocerca volvulus 0.0015 0.0223 0.0489
Brugia malayi Nuclear hormone receptor-like 1 0.0013 0.0143 0.0363
Loa Loa (eye worm) hypothetical protein 0.0013 0.0143 0.0354
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0015 0.0223 0.0489
Loa Loa (eye worm) hypothetical protein 0.0012 0.0096 0.0233
Schistosoma mansoni amine GPCR 0.0015 0.0223 0.0193
Schistosoma mansoni nuclear hormone receptor 0.0012 0.0096 0.0064
Brugia malayi mbt repeat family protein 0.0049 0.1382 0.3507
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0024 0.0538 0.0512
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0015 0.0223 0.0193
Echinococcus granulosus somatostatin receptor 0.0015 0.0223 0.0347
Loa Loa (eye worm) DR-78 0.0012 0.0096 0.0233
Brugia malayi G-protein coupled receptor 0.0015 0.0223 0.0566
Loa Loa (eye worm) hypothetical protein 0.0015 0.0223 0.0557
Brugia malayi hypothetical protein 0.0015 0.0223 0.0566
Echinococcus granulosus centrosomal protein of 41 kDa 0.001 0.0032 0.0045
Loa Loa (eye worm) hypothetical protein 0.001 0.0032 0.0071
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0012 0.0096 0.0145
Echinococcus granulosus Nuclear hormone receptor HR96 0.0012 0.0096 0.0145
Mycobacterium ulcerans hypothetical protein 0.0159 0.5126 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0223 0.0557
Loa Loa (eye worm) hypothetical protein 0.001 0.0032 0.0071
Brugia malayi Nuclear hormone receptor-like 1 0.0013 0.0143 0.0363
Loa Loa (eye worm) hypothetical protein 0.0024 0.0538 0.1357
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0301 1 1
Toxoplasma gondii histone lysine methyltransferase SET1 0.0054 0.1556 1
Brugia malayi Protein kinase domain containing protein 0.0015 0.0208 0.0527
Brugia malayi Thiosulfate sulfurtransferase D2023.5 0.001 0.0032 0.0081
Echinococcus granulosus ecdysone induced protein 78C 0.0024 0.0538 0.0845
Loa Loa (eye worm) hypothetical protein 0.0114 0.3609 0.9159
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0013 0.0143 0.0354
Echinococcus multilocularis neuropeptide receptor 0.0015 0.0223 0.0347
Loa Loa (eye worm) hypothetical protein 0.0012 0.0096 0.0233
Plasmodium vivax mitogen-activated protein kinase phosphatase 1, putative 0.001 0.0032 0.5
Loa Loa (eye worm) hypothetical protein 0.0015 0.0223 0.0557
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0142 0.4575 0.4558
Onchocerca volvulus 0.0015 0.0223 0.0489
Schistosoma mansoni nuclear receptor 0.0012 0.0096 0.0064
Loa Loa (eye worm) hypothetical protein 0.0013 0.0143 0.0354
Echinococcus granulosus neuropeptide receptor A26 0.0015 0.0223 0.0347
Toxoplasma gondii hypothetical protein 0.0049 0.1362 0.8725
Brugia malayi Rhodanese-like domain containing protein 0.0124 0.394 1
Echinococcus granulosus jun protein 0.0098 0.3055 0.4827
Trichomonas vaginalis m-phase inducer phosphatase, putative 0.0124 0.394 1
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0024 0.0538 0.0845
Brugia malayi RE15519p 0.0015 0.0223 0.0566
Onchocerca volvulus Netrin receptor homolog 0.0015 0.0208 0.0449
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0015 0.0223 0.0193
Brugia malayi Rhodanese-like domain containing protein 0.001 0.0032 0.0081
Schistosoma mansoni thyroid hormone receptor 0.0024 0.0538 0.0512
Brugia malayi hypothetical protein 0.0015 0.0223 0.0566
Brugia malayi AKH receptor 0.0015 0.0223 0.0566
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0024 0.0538 0.0845
Schistosoma mansoni retinoic acid receptor RXR 0.0024 0.0538 0.0512
Schistosoma mansoni adenoreceptor 0.0015 0.0223 0.0193
Loa Loa (eye worm) hypothetical protein 0.0015 0.0223 0.0557
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0024 0.0538 0.0845
Schistosoma mansoni RAR-like nuclear receptor 0.0024 0.0538 0.0512
Loa Loa (eye worm) hypothetical protein 0.001 0.0032 0.0071
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0024 0.0538 0.1357
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0301 1 1
Echinococcus granulosus alpha 1A adrenergic receptor 0.0015 0.0223 0.0347
Brugia malayi Tachykinin-like peptides receptor 99D 0.0015 0.0223 0.0566
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0024 0.0538 0.1365
Schistosoma mansoni biogenic amine (5HT) receptor 0.0015 0.0223 0.0193
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0056 0.1615 0.2548
Loa Loa (eye worm) hypothetical protein 0.0015 0.0223 0.0557
Echinococcus granulosus SAM and MBT domain containing protein 0.0049 0.1382 0.218
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0015 0.0223 0.0193
Brugia malayi hypothetical protein 0.0015 0.0223 0.0566
Onchocerca volvulus 0.0015 0.0223 0.0489
Brugia malayi hypothetical protein 0.0012 0.0096 0.0243
Brugia malayi Cytochrome P450 family protein 0.0013 0.0134 0.0341
Schistosoma mansoni hypothetical protein 0.0015 0.0223 0.0193
Brugia malayi hypothetical protein 0.0015 0.0223 0.0566
Echinococcus granulosus biogenic amine 5HT receptor 0.0015 0.0223 0.0347
Echinococcus multilocularis G-protein coupled receptor, putative 0.0015 0.0223 0.0347
Onchocerca volvulus 0.0015 0.0223 0.0489
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0012 0.0096 0.0145
Echinococcus granulosus G protein coupled receptor 139 0.0015 0.0223 0.0347
Loa Loa (eye worm) hypothetical protein 0.0009 0.001 0.0015
Schistosoma mansoni amine GPCR 0.0015 0.0223 0.0193
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0024 0.0538 0.0512
Loa Loa (eye worm) hypothetical protein 0.0124 0.394 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0223 0.0347
Brugia malayi ORL1-like opioid receptor 0.0015 0.0223 0.0566
Echinococcus granulosus 5'partial|tRNA 2 selenouridine synthase 0.001 0.0032 0.0045
Loa Loa (eye worm) hypothetical protein 0.0012 0.0096 0.0233
Loa Loa (eye worm) hypothetical protein 0.0015 0.0223 0.0557
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0052 0.1466 0.1438
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0024 0.0538 0.0845
Onchocerca volvulus 0.0029 0.068 0.1659
Brugia malayi G-protein coupled receptor 0.0015 0.0223 0.0566
Loa Loa (eye worm) hypothetical protein 0.0049 0.1382 0.3501
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0015 0.0223 0.0347
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0024 0.0538 0.0845
Echinococcus granulosus fmrfamide receptor 0.0015 0.0223 0.0347
Loa Loa (eye worm) hypothetical protein 0.0012 0.0096 0.0233
Brugia malayi nuclear receptor RXR 0.0012 0.0096 0.0243
Brugia malayi G protein-coupled receptor F59B2.13 0.0015 0.0223 0.0566
Entamoeba histolytica rodhanase-like domain containing protein 0.0124 0.394 1
Brugia malayi nuclear hormone receptor 0.0024 0.0538 0.1365
Loa Loa (eye worm) hypothetical protein 0.0024 0.0538 0.1357
Brugia malayi neuropeptide F receptor 0.0015 0.0223 0.0566
Brugia malayi photoreceptor-specific nuclear receptor 0.0024 0.0538 0.1365
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0015 0.0223 0.0193
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0012 0.0096 0.0145
Brugia malayi neuropeptide F receptor 0.0015 0.0223 0.0566
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0223 0.0347
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0015 0.0223 0.0193
Loa Loa (eye worm) hypothetical protein 0.0024 0.0538 0.1357
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0015 0.0223 0.0193
Schistosoma mansoni cpg binding protein 0.003 0.0736 0.0712
Echinococcus granulosus nuclear receptor nhr 48 0.0012 0.0096 0.0145
Brugia malayi hypothetical protein 0.0015 0.0223 0.0566
Brugia malayi Uncoordinated protein 44 0.0015 0.0208 0.0527
Loa Loa (eye worm) hypothetical protein 0.0013 0.0143 0.0354
Loa Loa (eye worm) hypothetical protein 0.0015 0.0223 0.0557
Schistosoma mansoni hypothetical protein 0.0015 0.0208 0.0178
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0013 0.0143 0.0112
Echinococcus multilocularis neuropeptide receptor A26 0.0015 0.0223 0.0347
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0015 0.0223 0.0566
Echinococcus granulosus g protein coupled receptor 0.0015 0.0223 0.0347
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0024 0.0538 0.1365
Brugia malayi Steroid receptor seven-up type 2 0.0024 0.0538 0.1365
Loa Loa (eye worm) cytochrome P450 family protein 0.0013 0.0134 0.0332
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0024 0.0538 0.0512
Onchocerca volvulus 0.0015 0.0223 0.0489
Echinococcus multilocularis SAM and MBT domain containing protein 0.0049 0.1382 0.218
Echinococcus multilocularis Rhodanese 0.001 0.0032 0.0045
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0015 0.0223 0.0347
Trichomonas vaginalis cdc25b, putative 0.0124 0.394 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0223 0.0557
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0223 0.0347
Loa Loa (eye worm) hypothetical protein 0.0015 0.0223 0.0557
Schistosoma mansoni neuropeptide F-like receptor 0.0015 0.0223 0.0193
Onchocerca volvulus 0.0015 0.0223 0.0489
Brugia malayi follicle stimulating hormone receptor 0.0015 0.0223 0.0566
Brugia malayi hypothetical protein 0.0015 0.0223 0.0566
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0015 0.0223 0.0193
Loa Loa (eye worm) nuclear receptor NHR-67 0.0012 0.0096 0.0233
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0223 0.0193
Onchocerca volvulus 0.0015 0.0223 0.0489
Loa Loa (eye worm) hypothetical protein 0.0015 0.0223 0.0557
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0015 0.0223 0.0557
Plasmodium falciparum mitogen-activated protein kinase phosphatase 1, putative 0.001 0.0032 0.5
Echinococcus multilocularis nuclear receptor nhr 48 0.0012 0.0096 0.0145
Brugia malayi hypothetical protein 0.0077 0.2335 0.5925
Loa Loa (eye worm) hypothetical protein 0.0015 0.0223 0.0557
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0049 0.1382 0.3454
Brugia malayi G protein-coupled receptor 0.0015 0.0223 0.0566
Loa Loa (eye worm) G-protein coupled receptor 0.0015 0.0223 0.0557
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0012 0.0096 0.0145
Brugia malayi Death domain containing protein 0.0015 0.0208 0.0527
Loa Loa (eye worm) MBCTL1 0.0056 0.1615 0.4092
Entamoeba histolytica rodhanase-like domain containing protein 0.0124 0.394 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0223 0.0347
Echinococcus granulosus neuropeptide FF receptor 2 0.0015 0.0223 0.0347
Echinococcus granulosus biogenic amine 5HT receptor 0.0015 0.0223 0.0347
Echinococcus granulosus histone acetyltransferase MYST2 0.0056 0.1615 0.2548
Loa Loa (eye worm) hypothetical protein 0.0015 0.0223 0.0557
Brugia malayi nuclear receptor NHR-67 0.0012 0.0096 0.0243
Onchocerca volvulus 0.0015 0.0223 0.0489
Echinococcus multilocularis g-protein coupled receptor 0.0015 0.0223 0.0347
Loa Loa (eye worm) cytochrome P450 family protein 0.0013 0.0134 0.0332
Echinococcus granulosus neuropeptide receptor 0.0015 0.0223 0.0347
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0015 0.0223 0.0193
Loa Loa (eye worm) hypothetical protein 0.0012 0.0096 0.0233
Echinococcus granulosus m phase inducer phosphatasecdc25 0.0124 0.394 0.6227
Loa Loa (eye worm) hypothetical protein 0.001 0.0032 0.0071
Onchocerca volvulus 0.0015 0.0223 0.0489
Loa Loa (eye worm) mbt repeat family protein 0.0049 0.1382 0.3501
Echinococcus multilocularis cpg binding protein 0.003 0.0736 0.1158
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0024 0.0538 0.0845
Echinococcus multilocularis serotonin receptor 0.0015 0.0223 0.0347
Brugia malayi ecdysteroid receptor 0.0024 0.0538 0.1365
Plasmodium vivax rhodanese like protein, putative 0.001 0.0032 0.5
Brugia malayi nuclear receptor NHR-88 0.0024 0.0538 0.1365
Echinococcus multilocularis g protein coupled receptor 0.0015 0.0223 0.0347
Onchocerca volvulus 0.0124 0.394 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0032 0.0071
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0024 0.0538 0.1357
Loa Loa (eye worm) hypothetical protein 0.0015 0.0212 0.0528
Loa Loa (eye worm) hypothetical protein 0.0012 0.0096 0.0233
Echinococcus granulosus peptide allatostatin:somatostatin 0.0015 0.0223 0.0347
Onchocerca volvulus 0.0124 0.394 1
Brugia malayi Nuclear hormone receptor E75 0.0012 0.0096 0.0243
Trypanosoma cruzi cytochrome P450, putative 0.0013 0.0134 0.0103
Loa Loa (eye worm) hypothetical protein 0.0012 0.0096 0.0233
Echinococcus granulosus Ankyrin 0.0015 0.0212 0.0329
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0012 0.0096 0.0163
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0015 0.0223 0.0557
Echinococcus granulosus dro:myosuppressin receptor 0.0015 0.0223 0.0347
Echinococcus granulosus thyroid hormone receptor alpha 0.0012 0.0096 0.0145
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0015 0.0223 0.0566
Schistosoma mansoni opsin-like receptor 0.0015 0.0223 0.0193
Loa Loa (eye worm) hypothetical protein 0.0015 0.0223 0.0557
Loa Loa (eye worm) hypothetical protein 0.0015 0.0223 0.0557
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0015 0.0208 0.0322
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0024 0.0538 0.1365
Loa Loa (eye worm) steroid hormone receptor 0.0024 0.0538 0.1357
Loa Loa (eye worm) hypothetical protein 0.0012 0.0096 0.0233
Schistosoma mansoni alpha-1 adrenergic receptor 0.0015 0.0223 0.0193
Echinococcus multilocularis neuropeptide s receptor 0.0015 0.0223 0.0347
Brugia malayi CXXC zinc finger family protein 0.0029 0.068 0.1726
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.068 0.1718
Mycobacterium leprae PROBABLE THIOSULFATE SULFURTRANSFERASE CYSA2 (RHODANESE-LIKE PROTEIN) (THIOSULFATE CYANIDE TRANSSULFURASE) (THIOSULFATE THIOTRAN 0.001 0.0032 0.5
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0024 0.0538 0.1365
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0223 0.0193
Trichomonas vaginalis cdc25b, putative 0.0124 0.394 1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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