Detailed information for compound 926649

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 340.37 | Formula: C20H20O5
  • H donors: 3 H acceptors: 3 LogP: 2.18 Rotable bonds: 0
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC1CCC2(C3C1C(O)C=CC3O)Oc1cccc3c1c(O2)ccc3
  • InChi: 1S/C20H20O5/c21-12-7-8-14(23)19-18(12)13(22)9-10-20(19)24-15-5-1-3-11-4-2-6-16(25-20)17(11)15/h1-8,12-14,18-19,21-23H,9-10H2
  • InChiKey: MTHUNPKHURTKGB-UHFFFAOYSA-N  


Substructure search Similarity search

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni kinase 0.0075 0.0309 0.0309
Echinococcus granulosus lamin 0.0021 0.0053 0.0052
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0187 0.0838 0.295
Echinococcus granulosus tyrosine protein kinase Src64B 0.0034 0.0115 0.0113
Loa Loa (eye worm) SH2 domain-containing protein 0.0034 0.0115 0.0137
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0148 0.065 0.0649
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0072 0.0293 0.5218
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0035 0.0118 0.0389
Schistosoma mansoni signal transduction protein lnk-related 0.0034 0.0115 0.0115
Echinococcus multilocularis c src tyrosine kinase 0.0034 0.0115 0.0113
Onchocerca volvulus 0.0012 0.0009 0.0141
Loa Loa (eye worm) hypothetical protein 0.0034 0.0115 0.0137
Schistosoma mansoni loxhd1 0.0013 0.0013 0.0013
Mycobacterium ulcerans hypothetical protein 0.0125 0.0542 1
Loa Loa (eye worm) hypothetical protein 0.0034 0.0115 0.0137
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0012 0.0009 0.0011
Trypanosoma cruzi cysteine peptidase, putative 0.0045 0.0165 0.0554
Echinococcus granulosus tyrosine protein kinase Lyn 0.0035 0.0118 0.0117
Plasmodium falciparum LCCL domain-containing protein 0.0013 0.0013 0.0151
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0072 0.0293 0.0291
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0034 0.0115 0.0113
Schistosoma mansoni hypothetical protein 0.0013 0.0013 0.0013
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0112 0.0482 0.1683
Schistosoma mansoni serine/threonine protein kinase 0.0036 0.0124 0.0124
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0072 0.0293 0.2954
Trichomonas vaginalis helicase, putative 0.0026 0.0075 0.0235
Brugia malayi Protein kinase domain containing protein 0.0034 0.0115 0.0137
Trichomonas vaginalis CMGC family protein kinase 0.0036 0.0124 0.0408
Trypanosoma cruzi DNA repair and recombination helicase protein PIF7, putative 0.0607 0.2818 1
Trypanosoma cruzi polo-like protein kinase, putative 0.0148 0.065 0.2283
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0034 0.0115 0.0113
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0014 0.0021 0.0043
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0034 0.0115 0.0113
Brugia malayi 6-phosphofructokinase 0.0076 0.0313 0.0373
Schistosoma mansoni cathepsin F (C01 family) 0.0012 0.0009 0.0009
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0036 0.0124 0.0408
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0013 0.0014 0.0162
Schistosoma mansoni hypothetical protein 0.0607 0.2818 0.2818
Schistosoma mansoni myst-related protein 0.0013 0.0017 0.0017
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0045 0.0165 0.0551
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.008 0.0331 0.0395
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0014 0.0021 0.004
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0021 0.0051 0.0149
Brugia malayi hypothetical protein 0.0013 0.0013 0.0016
Leishmania major ATP-dependent phosphofructokinase 0.0076 0.0313 0.1082
Echinococcus granulosus chromobox protein 1 0.0045 0.0164 0.0163
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0034 0.0115 0.0113
Loa Loa (eye worm) SH2 domain-containing protein 0.0034 0.0115 0.0137
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0036 0.0124 0.0408
Entamoeba histolytica hypothetical protein 0.0055 0.0215 0.0733
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0072 0.0293 0.3074
Schistosoma mansoni tyrosine kinase 0.0034 0.0115 0.0115
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0034 0.0115 0.0137
Onchocerca volvulus Cathepsin F homolog 0.0012 0.0009 0.0141
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0187 0.0838 0.295
Loa Loa (eye worm) hypothetical protein 0.0034 0.0115 0.0137
Leishmania major cytochrome p450-like protein 0.002 0.0048 0.0137
Entamoeba histolytica SH2 domain containing protein 0.0034 0.0115 0.0376
Brugia malayi Bloom's syndrome protein homolog 0.0013 0.0014 0.0016
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0021 0.0053 0.0064
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0034 0.0115 0.0113
Loa Loa (eye worm) TK/FER protein kinase 0.0034 0.0115 0.0137
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0076 0.0313 0.8011
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0034 0.0115 0.0137
Schistosoma mansoni hypothetical protein 0.0977 0.4563 0.4563
Brugia malayi Doublecortin family protein 0.0013 0.0013 0.0016
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0034 0.0115 0.0113
Brugia malayi Tyrosine-protein kinase abl-1 0.0034 0.0115 0.0137
Loa Loa (eye worm) TK protein kinase 0.0034 0.0115 0.0137
Plasmodium falciparum ataxin-2 like protein, putative 0.0041 0.0149 0.4946
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0034 0.0115 0.0115
Echinococcus multilocularis 0.0014 0.0021 0.002
Loa Loa (eye worm) hypothetical protein 0.0021 0.0053 0.0064
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0034 0.0115 0.0113
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0019 0.0042 0.004
Echinococcus granulosus tyrosine kinase 0.0034 0.0115 0.0113
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0072 0.0293 0.7453
Loa Loa (eye worm) hypothetical protein 0.0013 0.0014 0.0016
Echinococcus multilocularis SH2 motif 0.0034 0.0115 0.0113
Loa Loa (eye worm) hypothetical protein 0.0013 0.0013 0.0016
Echinococcus granulosus SH2 domain containing protein 7 0.0034 0.0115 0.0113
Schistosoma mansoni myst-related protein 0.0013 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0034 0.0115 0.0137
Schistosoma mansoni cathepsin F (C01 family) 0.0012 0.0009 0.0009
Echinococcus granulosus tyrosine protein kinase Fyn 0.0034 0.0115 0.0113
Loa Loa (eye worm) SRC-1 0.0034 0.0115 0.0137
Echinococcus granulosus SH2 motif 0.0034 0.0115 0.0113
Loa Loa (eye worm) hypothetical protein 0.0013 0.0013 0.0016
Schistosoma mansoni vav2 0.0034 0.0115 0.0115
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0095 0.0401 0.729
Mycobacterium ulcerans aldehyde dehydrogenase 0.0095 0.0401 0.729
Leishmania major cathepsin L-like protease 0.0045 0.0165 0.0554
Echinococcus granulosus tensin 0.0034 0.0115 0.0113
Onchocerca volvulus 0.0034 0.0115 0.1764
Schistosoma mansoni shc transforming protein 0.0034 0.0115 0.0115
Onchocerca volvulus 0.0012 0.0009 0.0141
Loa Loa (eye worm) hypothetical protein 0.001 0.0002 0.0002
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0076 0.0313 0.5609
Loa Loa (eye worm) apoptosis regulator protein 0.0058 0.0226 0.027
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0013 0.0014 0.0048
Echinococcus granulosus tyrosine protein kinase ABL1 0.0034 0.0115 0.0113
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0072 0.0293 0.5218
Brugia malayi SH2 domain containing protein 0.0034 0.0115 0.0137
Brugia malayi Cytochrome P450 family protein 0.002 0.0048 0.0057
Echinococcus granulosus lipoxygenase domain containing protein 0.0013 0.0013 0.0012
Schistosoma mansoni hypothetical protein 0.0382 0.1755 0.1755
Schistosoma mansoni suppressor of cytokine signaling 0.0034 0.0115 0.0115
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0241 0.109 0.109
Loa Loa (eye worm) cytochrome P450 family protein 0.0062 0.0244 0.0291
Brugia malayi Cytochrome P450 family protein 0.0062 0.0244 0.0291
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0033 0.011 0.0358
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0045 0.0165 0.0551
Brugia malayi hypothetical protein 0.0055 0.0215 0.0256
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0037 0.0101
Onchocerca volvulus 0.0034 0.0115 0.1764
Brugia malayi F/Y-rich N-terminus family protein 0.0035 0.0117 0.014
Loa Loa (eye worm) phosphofructokinase 0.0076 0.0313 0.0373
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0034 0.0115 0.0113
Schistosoma mansoni hypothetical protein 0.0014 0.0021 0.0021
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0014 0.0021 0.0043
Onchocerca volvulus 0.0034 0.0115 0.1764
Schistosoma mansoni hypothetical protein 0.0034 0.0115 0.0115
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0045 0.0165 0.0551
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0034 0.0115 0.0137
Echinococcus granulosus mitogen activated protein kinase 0.0036 0.0124 0.0122
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0034 0.0115 0.0113
Leishmania major cytochrome p450-like protein 0.0014 0.0021 0.0043
Trypanosoma cruzi ISWI complex protein 0.0012 0.001 0.0003
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0025 0.0072 0.1106
Schistosoma mansoni hypothetical protein 0.001 0.0002 0.0002
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0014 0.0019 0.0019
Schistosoma mansoni tensin 0.0034 0.0115 0.0115
Brugia malayi SH2 domain containing protein 0.0034 0.0115 0.0137
Schistosoma mansoni tyrosine kinase 0.0034 0.0115 0.0115
Entamoeba histolytica protein kinase, putative 0.0035 0.0118 0.0389
Echinococcus granulosus tyrosine protein kinase Src42A 0.0034 0.0115 0.0113
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0047 0.0176 0.2974
Echinococcus granulosus mitogen activated protein kinase 3 0.0036 0.0124 0.0122
Echinococcus granulosus growth factor receptor bound protein 2 0.0034 0.0115 0.0113
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0072 0.0293 1
Schistosoma mansoni chromobox protein 0.0045 0.0164 0.0164
Onchocerca volvulus 0.0034 0.0115 0.1764
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0034 0.0115 0.0115
Brugia malayi Calcitonin receptor-like protein seb-1 0.0032 0.0105 0.0125
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0014 0.0013
Echinococcus multilocularis tensin 0.0034 0.0115 0.0113
Echinococcus granulosus tyrosine protein kinase Fyn 0.0034 0.0115 0.0113
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0036 0.0124 0.1193
Onchocerca volvulus 0.0034 0.0115 0.1764
Brugia malayi Latrophilin receptor protein 2 0.001 0.0002 0.0002
Echinococcus multilocularis cathepsin L cysteine protease 0.0012 0.0009 0.0008
Loa Loa (eye worm) CXXC zinc finger family protein 0.0114 0.049 0.0584
Schistosoma mansoni tensin-related 0.0034 0.0115 0.0115
Schistosoma mansoni 6-phosphofructokinase 0.0076 0.0313 0.0313
Trichomonas vaginalis CAMK family protein kinase 0.0148 0.065 0.2283
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0237 0.107 0.3774
Brugia malayi hypothetical protein 0.0034 0.0115 0.0137
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0032 0.0105 0.0125
Onchocerca volvulus 0.0012 0.0009 0.0141
Echinococcus multilocularis 6 phosphofructokinase 0.0076 0.0313 0.0312
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0076 0.0313 0.3333
Leishmania major hypothetical protein, conserved 0.0041 0.0149 0.0499
Toxoplasma gondii aldehyde dehydrogenase 0.0095 0.0401 0.4078
Echinococcus granulosus cytochrome P450 2K1 0.0014 0.0021 0.002
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0187 0.0838 0.295
Schistosoma mansoni SH2A 0.0034 0.0115 0.0115
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0034 0.0115 0.0115
Schistosoma mansoni hypothetical protein 0.0039 0.0139 0.0139
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0034 0.0115 0.0376
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0034 0.0115 0.0113
Brugia malayi SH2 domain containing protein 0.0034 0.0115 0.0137
Schistosoma mansoni tar DNA-binding protein 0.0111 0.0476 0.0476
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0028 0.0087 0.0087
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0037 0.0101
Giardia lamblia Kinase, CMGC MAPK 0.0036 0.0124 0.0392
Trichomonas vaginalis CAMK family protein kinase 0.0148 0.065 0.2283
Onchocerca volvulus 0.0034 0.0115 0.1764
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0033 0.011 0.0358
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0021 0.0051 0.1471
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0095 0.0401 0.1394
Entamoeba histolytica hypothetical protein 0.0055 0.0215 0.0733
Echinococcus granulosus signal transduction protein lnk realted 0.0034 0.0115 0.0113
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0045 0.0165 0.0551
Brugia malayi chromobox protein homolog 3 0.0025 0.0072 0.0086
Onchocerca volvulus Cathepsin L homolog 0.0012 0.0009 0.0141
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.001 0.0002 0.0002
Echinococcus granulosus N chimaerin 0.0034 0.0115 0.0113
Onchocerca volvulus Cathepsin L homolog 0.0012 0.0009 0.0141
Echinococcus granulosus tyrosine protein kinase Srms 0.0034 0.0115 0.0113
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0047 0.0176 0.2974
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0055 0.0215 0.0213
Echinococcus multilocularis cathepsin L cysteine protease 0.0012 0.0009 0.0008
Loa Loa (eye worm) TK/FER protein kinase 0.0034 0.0115 0.0137
Plasmodium vivax multidomain scavenger receptor, putative 0.0013 0.0013 0.0151
Echinococcus granulosus suppressor of cytokine signaling 7 0.0034 0.0115 0.0113
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0034 0.0115 0.0113
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0034 0.0115 0.0113
Toxoplasma gondii hypothetical protein 0.0025 0.0071 0.064
Trypanosoma cruzi DNA repair and recombination helicase protein PIF7, putative 0.0607 0.2818 1
Schistosoma mansoni GTPase activating protein 0.0034 0.0115 0.0115
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0021 0.0051 0.0435
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0058 0.0226 0.0226
Toxoplasma gondii 6-phosphofructokinase 0.0021 0.0051 0.0435
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0033 0.011 0.0358
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0032 0.0105 0.0125
Echinococcus granulosus dnaJ subfamily C 6 0.0039 0.0139 0.0138
Trichomonas vaginalis chromobox protein, putative 0.0027 0.0081 0.0255
Schistosoma mansoni rab6-interacting 0.0013 0.0013 0.0013
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0034 0.0115 0.0115
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0033 0.0111 0.0362
Mycobacterium tuberculosis Conserved hypothetical protein 0.0125 0.0542 1
Entamoeba histolytica phosphofructokinase, putative 0.0076 0.0313 0.1082
Trichomonas vaginalis CMGC family protein kinase 0.0036 0.0124 0.0408
Schistosoma mansoni aldehyde dehydrogenase 0.0095 0.0401 0.0401
Echinococcus multilocularis dnaJ subfamily C 6 0.0039 0.0139 0.0138
Loa Loa (eye worm) TK/FER protein kinase 0.0034 0.0115 0.0137
Brugia malayi hypothetical protein 0.0013 0.0013 0.0016
Trypanosoma cruzi cysteine peptidase, putative 0.0045 0.0165 0.0554
Trichomonas vaginalis CMGC family protein kinase 0.0036 0.0124 0.0408
Echinococcus multilocularis cysteine protease 0.0012 0.0009 0.0008
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0047 0.0176 0.4248
Echinococcus granulosus hypothetical protein 0.0034 0.0115 0.0113
Schistosoma mansoni hypothetical protein 0.0058 0.0226 0.0226
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0033 0.011 0.0358
Echinococcus granulosus ATP dependent DNA helicase PIF1 0.0607 0.2818 0.2816
Echinococcus multilocularis SH2 motif 0.0034 0.0115 0.0113
Onchocerca volvulus 0.0021 0.0053 0.0822
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0013 0.0014 0.0016
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.0034 0.0115 0.1764
Brugia malayi hypothetical protein 0.0027 0.008 0.0095
Schistosoma mansoni rab6-interacting 0.0013 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0034 0.0115 0.0137
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0045 0.0165 0.0551
Schistosoma mansoni DNA helicase recq1 0.0013 0.0014 0.0014
Brugia malayi Protein kinase domain containing protein 0.0034 0.0115 0.0137
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0092 0.0386 0.7001
Onchocerca volvulus 0.0012 0.0009 0.0141
Schistosoma mansoni tar DNA-binding protein 0.0111 0.0476 0.0476
Brugia malayi Intermediate filament tail domain containing protein 0.0021 0.0053 0.0064
Onchocerca volvulus 0.0034 0.0115 0.1764
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0187 0.0838 0.295
Trypanosoma cruzi major cysteine proteinase, putative 0.0035 0.012 0.0393
Brugia malayi Cathepsin L-like precursor 0.0012 0.0009 0.0011
Brugia malayi Protein kinase domain containing protein 0.0034 0.0115 0.0137
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0076 0.031 0.0309
Echinococcus multilocularis tyrosine protein kinase Blk 0.0034 0.0115 0.0113
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0025 0.0071 0.2166
Trichomonas vaginalis DNA helicase recq, putative 0.0013 0.0014 0.0016
Schistosoma mansoni peptidase Clp (S14 family) 0.0072 0.0293 0.0293
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0045 0.0165 0.0551
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0187 0.0838 0.295
Schistosoma mansoni 6-phosphofructokinase 0.0076 0.0313 0.0313
Plasmodium vivax 6-phosphofructokinase, putative 0.0021 0.0051 0.1471
Schistosoma mansoni chromobox protein 0.0045 0.0164 0.0164
Schistosoma mansoni tyrosine kinase 0.0034 0.0115 0.0115
Loa Loa (eye worm) 6-phosphofructokinase 0.0076 0.0313 0.0373
Schistosoma mansoni tensin-related 0.0034 0.0115 0.0115
Trichomonas vaginalis DNA helicase recq1, putative 0.0013 0.0014 0.0016
Trypanosoma cruzi cytochrome P450, putative 0.002 0.0048 0.0137
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0013 0.0014 0.0162
Loa Loa (eye worm) heterochromatin protein 1 0.0045 0.0164 0.0196
Brugia malayi MAP kinase sur-1 0.0036 0.0124 0.0148
Mycobacterium ulcerans 6-phosphofructokinase 0.0076 0.0313 0.5609
Schistosoma mansoni hypothetical protein 0.0022 0.0057 0.0057
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0092 0.0386 0.7001
Echinococcus multilocularis mitogen activated protein kinase 0.0036 0.0124 0.0122
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0075 0.0235
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0012 0.0009 0.0011
Echinococcus granulosus 6 phosphofructokinase 0.0076 0.0313 0.0312
Toxoplasma gondii hypothetical protein 0.0038 0.0134 0.1298
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0045 0.0165 0.0551
Echinococcus multilocularis RUN 0.0013 0.0013 0.0012
Brugia malayi latrophilin 2 splice variant baaae 0.0022 0.0057 0.0068
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0013 0.0014 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0075 0.0235
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0072 0.0293 1
Onchocerca volvulus 0.0034 0.0115 0.1764
Echinococcus multilocularis N chimaerin 0.0034 0.0115 0.0113
Echinococcus granulosus dnaJ subfamily B 0.0977 0.4563 0.4562
Trichomonas vaginalis CAMK family protein kinase 0.0148 0.065 0.2283
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0095 0.0401 0.0399
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0045 0.0165 0.0551
Echinococcus granulosus tensin C1 domain containing phosphatase 0.0034 0.0115 0.0113
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0033 0.011 0.0358
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0034 0.0115 0.0113
Schistosoma mansoni growth factor receptor-bound protein 0.0034 0.0115 0.0115
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0033 0.0111 0.0358
Loa Loa (eye worm) hypothetical protein 0.0034 0.0115 0.0137
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0033 0.011 0.0358
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0045 0.0126
Loa Loa (eye worm) hypothetical protein 0.0032 0.0105 0.0125
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0033 0.0111 0.0362
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0072 0.0223
Brugia malayi Cytochrome P450 family protein 0.002 0.0048 0.0057
Schistosoma mansoni intermediate filament proteins 0.0021 0.0053 0.0053
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0034 0.0115 0.0113
Mycobacterium ulcerans aldehyde dehydrogenase 0.0095 0.0401 0.729
Schistosoma mansoni tar DNA-binding protein 0.0111 0.0476 0.0476
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0014 0.0016
Schistosoma mansoni hypothetical protein 0.0034 0.0115 0.0115
Loa Loa (eye worm) hypothetical protein 0.0034 0.0115 0.0137
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0041 0.0145 0.0484
Loa Loa (eye worm) hypothetical protein 0.0034 0.0115 0.0137
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0034 0.0115 0.0137
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0041 0.0146 0.0489
Toxoplasma gondii histone lysine methyltransferase SET1 0.0215 0.0969 1
Brugia malayi Variant SH3 domain containing protein 0.0034 0.0115 0.0137
Onchocerca volvulus Serine\/threonine kinase homolog 0.0148 0.065 1
Brugia malayi Sex muscle abnormal protein 5 0.0034 0.0115 0.0137
Trypanosoma brucei polo-like protein kinase 0.0148 0.065 0.2281
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1983 0.9307 0.9307
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0045 0.0165 0.0551
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0237 0.107 0.3776
Loa Loa (eye worm) doublecortin family protein 0.0013 0.0013 0.0016
Loa Loa (eye worm) TK/FER protein kinase 0.0034 0.0115 0.0137
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0148 0.065 0.0775
Trichomonas vaginalis CAMK family protein kinase 0.0148 0.065 0.2283
Schistosoma mansoni hypothetical protein 0.001 0.0002 0.0002
Echinococcus multilocularis peptidase Clp (S14 family) 0.0047 0.0176 0.0174
Echinococcus multilocularis NCK adaptor protein 0.0034 0.0115 0.0113
Loa Loa (eye worm) RecQ helicase 0.0013 0.0014 0.0016
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.008 0.0331 0.0329
Schistosoma mansoni aldehyde dehydrogenase 0.0095 0.0401 0.0401
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0013 0.0014 0.0012
Trichomonas vaginalis phosphofructokinase, putative 0.0076 0.0313 0.1082
Brugia malayi cytokine inducible SH2-containing protein 5 0.0034 0.0115 0.0137
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0075 0.0235
Trichomonas vaginalis phosphofructokinase, putative 0.0021 0.0051 0.0149
Echinococcus granulosus tyrosine protein kinase Blk 0.0034 0.0115 0.0113
Brugia malayi phosphofructokinase 0.0076 0.0313 0.0373
Brugia malayi cytoplasmic intermediate filament protein 0.0011 0.0007 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0075 0.0235
Toxoplasma gondii cytochrome p450 superfamily protein 0.0014 0.0021 0.0126
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0011 0.0007 0.0008
Giardia lamblia Kinase, PLK 0.0148 0.065 0.227
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0058 0.0226 0.0225
Schistosoma mansoni cpg binding protein 0.012 0.052 0.052
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0025 0.0071 0.2166
Echinococcus multilocularis 0.0034 0.0115 0.0113
Echinococcus granulosus cathepsin l cysteine peptidase 0.0012 0.0009 0.0008
Schistosoma mansoni hypothetical protein 0.001 0.0002 0.0002
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0013 0.0014 0.0012
Echinococcus granulosus peptidase Clp S14 family 0.0047 0.0176 0.0174
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0045 0.0165 0.0551
Schistosoma mansoni tyrosine kinase 0.0034 0.0115 0.0115
Trypanosoma brucei PAB1-binding protein , putative 0.0041 0.0149 0.0496
Schistosoma mansoni tar DNA-binding protein 0.0111 0.0476 0.0476
Trypanosoma cruzi cytochrome P450, putative 0.002 0.0048 0.0137
Toxoplasma gondii phosphofructokinase PFKII 0.0021 0.0051 0.0435
Loa Loa (eye worm) hypothetical protein 0.0034 0.0115 0.0137
Onchocerca volvulus 0.002 0.0046 0.0713
Echinococcus multilocularis neuropeptide receptor A26 0.1146 0.5357 0.5356
Loa Loa (eye worm) TK/FER protein kinase 0.0034 0.0115 0.0137
Onchocerca volvulus 0.0012 0.0009 0.0141
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0013 0.0014 0.0016
Echinococcus granulosus Polycystic kidney disease protein 0.0013 0.0013 0.0012
Brugia malayi SH2 domain containing protein 0.0034 0.0115 0.0137
Schistosoma mansoni hypothetical protein 0.0058 0.0226 0.0226
Plasmodium vivax 6-phosphofructokinase, putative 0.0021 0.0051 0.1471
Schistosoma mansoni cytochrome P450 0.0014 0.0021 0.0021
Echinococcus granulosus geminin 0.0382 0.1755 0.1754
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0036 0.0124 0.0408
Schistosoma mansoni growth factor receptor-bound protein 0.0034 0.0115 0.0115
Brugia malayi serine/threonine-protein kinase plk-2 0.0148 0.065 0.0775
Echinococcus multilocularis lipoxygenase domain containing protein 0.0013 0.0013 0.0012
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0034 0.0115 0.0113
Loa Loa (eye worm) cytochrome P450 0.0014 0.0021 0.0025
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0033 0.011 0.0358
Loa Loa (eye worm) TK/FER protein kinase 0.0034 0.0115 0.0137
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0045 0.0165 0.0551
Trichomonas vaginalis chromobox protein, putative 0.0027 0.0081 0.0255
Trichomonas vaginalis CAMK family protein kinase 0.0073 0.0299 0.1033
Brugia malayi hypothetical protein 0.0041 0.0149 0.0178
Echinococcus multilocularis lipoxygenase domain containing protein 0.0013 0.0013 0.0012
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0111 0.0476 0.0568
Brugia malayi Protein kinase domain containing protein 0.0034 0.0115 0.0137
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0034 0.0115 0.0113
Echinococcus granulosus SH2 motif 0.0034 0.0115 0.0113
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0072 0.0293 0.0291
Trypanosoma cruzi cruzipain precursor, putative 0.0045 0.0165 0.0554
Loa Loa (eye worm) cysteine protease 0.0012 0.0009 0.0011
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0021 0.0051 0.1471
Trichomonas vaginalis chromobox protein, putative 0.0045 0.0164 0.0553
Onchocerca volvulus 0.0021 0.0053 0.0822
Loa Loa (eye worm) hypothetical protein 0.0025 0.0072 0.0086
Leishmania major PIF1 helicase-like protein, putative,DNA repair and recombination protein, mitochondrial precursor, putative 0.0607 0.2818 1
Echinococcus multilocularis geminin 0.0382 0.1755 0.1754
Schistosoma mansoni cpg binding protein 0.012 0.052 0.052
Brugia malayi protein-tyrosine kinase 0.0034 0.0115 0.0137
Brugia malayi SH2 domain containing protein 0.0034 0.0115 0.0137
Trichomonas vaginalis DNA helicase recq, putative 0.0013 0.0014 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0072 0.0223
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0034 0.0115 0.0115
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0021 0.0051 0.0132
Echinococcus granulosus RUN 0.0013 0.0013 0.0012
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0072 0.0293 1
Schistosoma mansoni polycystin 1-related 0.0013 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0034 0.0115 0.0137
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0148 0.065 0.0649
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0025 0.0071 0.025
Echinococcus multilocularis SH2 domain containing protein 7 0.0034 0.0115 0.0113
Brugia malayi SRC-1 0.0034 0.0115 0.0137
Mycobacterium ulcerans aldehyde dehydrogenase 0.0095 0.0401 0.729
Echinococcus multilocularis ATP dependent DNA helicase PIF1 0.0607 0.2818 0.2816
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.008 0.0331 0.0329
Brugia malayi SH2 domain containing protein 0.0034 0.0115 0.0137
Schistosoma mansoni serine/threonine protein kinase 0.0148 0.065 0.065
Brugia malayi Variant SH3 domain containing protein 0.0034 0.0115 0.0137
Entamoeba histolytica DNA repair and recombination protein, putative 0.0607 0.2818 1
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0058 0.0226 0.0225
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0014 0.0019 0.0017
Brugia malayi Cathepsin L-like precursor 0.0012 0.0009 0.0011
Loa Loa (eye worm) TK/FER protein kinase 0.0034 0.0115 0.0137
Plasmodium falciparum zinc finger protein, putative 0.0013 0.0017 0.0278
Echinococcus multilocularis tyrosine kinase 0.0034 0.0115 0.0113
Brugia malayi SH2 domain containing protein 0.0034 0.0115 0.0137
Echinococcus multilocularis SHC transforming protein 3 0.0034 0.0115 0.0113
Echinococcus granulosus intermediate filament protein 0.0021 0.0053 0.0052
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0014 0.0021 0.0043
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0076 0.031 0.0309
Leishmania major cytochrome p450-like protein 0.0014 0.0021 0.0043
Echinococcus granulosus neuropeptide receptor A26 0.1146 0.5357 0.5356
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0028 0.0087 0.0085
Echinococcus granulosus tyrosine protein kinase Fyn 0.0034 0.0115 0.0113
Brugia malayi STAT protein, DNA binding domain containing protein 0.1788 0.8386 1
Loa Loa (eye worm) hypothetical protein 0.0041 0.0149 0.0178
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0075 0.0235
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0034 0.0115 0.0113
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0237 0.107 0.3776
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.001 0.0003
Schistosoma mansoni tensin 0.0034 0.0115 0.0115
Echinococcus multilocularis cysteine protease 0.0012 0.0009 0.0008
Loa Loa (eye worm) TK/FER protein kinase 0.0034 0.0115 0.0137
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.0034 0.0115 0.1764
Brugia malayi 6-phosphofructokinase 0.0076 0.0313 0.0373
Trichomonas vaginalis CAMK family protein kinase 0.0148 0.065 0.2283
Entamoeba histolytica recQ family helicase, putative 0.0013 0.0014 0.0016
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0013 0.0014 0.0016
Echinococcus granulosus tyrosine kinase 0.0034 0.0115 0.0113
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0014 0.0021 0.0043
Loa Loa (eye worm) hypothetical protein 0.0058 0.0226 0.027
Brugia malayi intermediate filament protein 0.0021 0.0053 0.0064
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0034 0.0115 0.0113
Trichomonas vaginalis CAMK family protein kinase 0.0073 0.0299 0.1033
Trichomonas vaginalis CAMK family protein kinase 0.0148 0.065 0.2283
Entamoeba histolytica serine/threonine protein kinase, putative 0.0148 0.065 0.2283
Loa Loa (eye worm) intermediate filament protein 0.0021 0.0053 0.0064
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0034 0.0115 0.0137
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0072 0.0293 0.5
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0058 0.0226 0.0225
Echinococcus granulosus tyrosine protein kinase shark 0.0034 0.0115 0.0113
Echinococcus multilocularis lamin dm0 0.0021 0.0053 0.0052
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0021 0.0053 0.0158
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0012 0.0009 0.0008
Schistosoma mansoni nck2/grb4 0.0034 0.0115 0.0115
Echinococcus granulosus SH2 domain containing adapter protein F 0.0034 0.0115 0.0113
Echinococcus granulosus NCK adaptor protein 0.0034 0.0115 0.0113
Onchocerca volvulus 0.0013 0.0013 0.0207
Echinococcus multilocularis SH2 motif 0.0034 0.0115 0.0113
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0011
Schistosoma mansoni tyrosine kinase 0.0034 0.0115 0.0115
Toxoplasma gondii LsmAD domain-containing protein 0.0041 0.0149 0.1461
Trichomonas vaginalis phosphofructokinase, putative 0.0021 0.0051 0.0149
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0033 0.0111 0.0362
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0036 0.0124 0.0408
Loa Loa (eye worm) STAT protein 0.1788 0.8386 1
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0112 0.0482 0.1683
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0034 0.0115 0.0113
Schistosoma mansoni lamin 0.0021 0.0053 0.0053
Echinococcus granulosus lamin dm0 0.0021 0.0053 0.0052
Loa Loa (eye worm) latrophilin receptor protein 2 0.001 0.0002 0.0002
Trypanosoma cruzi DNA repair and recombination helicase protein PIF6, putative 0.0607 0.2818 1
Loa Loa (eye worm) fibroinase 0.0012 0.0009 0.0011
Trichomonas vaginalis phosphofructokinase, putative 0.0076 0.0313 0.1082
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0025 0.0071 0.1355
Entamoeba histolytica hypothetical protein 0.0055 0.0215 0.0733
Echinococcus multilocularis tyrosine protein kinase Abl 0.0034 0.0115 0.0113
Brugia malayi Probable ClpP-like protease 0.0072 0.0293 0.0349
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0055 0.0215 0.0213
Loa Loa (eye worm) CYP4Cod1 0.002 0.0048 0.0057
Onchocerca volvulus 0.0012 0.0009 0.0141
Brugia malayi DnaJ domain containing protein 0.0039 0.0139 0.0166
Loa Loa (eye worm) DnaJ domain-containing protein 0.0039 0.0139 0.0166
Loa Loa (eye worm) TK/FER protein kinase 0.0034 0.0115 0.0137
Echinococcus multilocularis Polycystic kidney disease protein 0.0013 0.0013 0.0012
Trichomonas vaginalis phosphofructokinase, putative 0.0076 0.0313 0.1082
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.008 0.0331 0.0329
Loa Loa (eye worm) hypothetical protein 0.0034 0.0115 0.0137
Schistosoma mansoni lamin 0.0021 0.0053 0.0053
Echinococcus granulosus lipoxygenase domain containing protein 0.0013 0.0013 0.0012
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0035 0.012 0.0118
Loa Loa (eye worm) CHromoDomain protein family member 0.0014 0.0019 0.0022
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0092 0.0386 1
Echinococcus granulosus tar DNA binding protein 0.0111 0.0476 0.0475
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0058 0.0226 0.027
Onchocerca volvulus 0.0114 0.049 0.7529
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0034 0.0115 0.0137
Brugia malayi SH2 domain containing protein 0.0034 0.0115 0.0137
Onchocerca volvulus 0.0034 0.0115 0.1764
Echinococcus multilocularis dnaJ subfamily B 0.0977 0.4563 0.4562
Giardia lamblia Rrm3p helicase 0.0607 0.2818 1
Brugia malayi TAR-binding protein 0.0111 0.0476 0.0568
Brugia malayi SH2 domain containing protein 0.0034 0.0115 0.0137
Brugia malayi CXXC zinc finger family protein 0.0114 0.049 0.0584
Loa Loa (eye worm) hypothetical protein 0.0034 0.0115 0.0137
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0034 0.0115 0.0113
Leishmania major cathepsin L-like protease 0.0045 0.0165 0.0554
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0076 0.0313 0.1079
Loa Loa (eye worm) RNA binding protein 0.0111 0.0476 0.0568
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0187 0.0838 0.295
Schistosoma mansoni apoptosis regulator bax 0.0058 0.0226 0.0226
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0034 0.0115 0.0113
Echinococcus multilocularis tar DNA binding protein 0.0111 0.0476 0.0475
Loa Loa (eye worm) hypothetical protein 0.0072 0.0293 0.0349
Brugia malayi Cathepsin L-like precursor 0.0012 0.0009 0.0011
Brugia malayi tRNA modification GTPase TrmE family protein 0.0034 0.0115 0.0137
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0036 0.0124 0.0408
Schistosoma mansoni lipoxygenase 0.0076 0.031 0.031
Echinococcus granulosus suppressor of cytokine signaling 6 0.0034 0.0115 0.0113
Loa Loa (eye worm) TAR-binding protein 0.0111 0.0476 0.0568
Trypanosoma brucei DNA repair and recombination helicase protein PIF6 0.0607 0.2818 1
Echinococcus multilocularis neuropeptide s receptor 0.1146 0.5357 0.5356
Onchocerca volvulus 0.0012 0.0009 0.0141
Schistosoma mansoni tar DNA-binding protein 0.0111 0.0476 0.0476
Brugia malayi Cytochrome P450 family protein 0.0014 0.0021 0.0025
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0112 0.0482 0.1681
Schistosoma mansoni hypothetical protein 0.0058 0.0226 0.0226
Brugia malayi CHD4 protein 0.0014 0.0019 0.0022
Schistosoma mansoni hypothetical protein 0.001 0.0002 0.0002
Loa Loa (eye worm) 6-phosphofructokinase 0.0076 0.0313 0.0373
Schistosoma mansoni transcription factor LCR-F1 0.0055 0.0215 0.0215
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0075 0.0235
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0034 0.0115 0.0113
Trichomonas vaginalis protein kinase inhibitor, putative 0.0039 0.0139 0.0462
Brugia malayi Variant SH3 domain containing protein 0.0034 0.0115 0.0137
Trichomonas vaginalis chromobox protein, putative 0.0045 0.0164 0.0553
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0187 0.0838 0.295
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0034 0.0115 0.0113
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0076 0.0313 0.1082
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0187 0.0838 0.295
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.008 0.0331 0.0329
Onchocerca volvulus 0.0034 0.0115 0.1764
Trichomonas vaginalis CMGC family protein kinase 0.0036 0.0124 0.0408
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0058 0.0226 0.0225
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0033 0.011 0.0358
Loa Loa (eye worm) hypothetical protein 0.0034 0.0115 0.0137
Trichomonas vaginalis phosphofructokinase, putative 0.0021 0.0051 0.0149
Entamoeba histolytica hypothetical protein 0.0055 0.0215 0.0733
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.008 0.0331 0.0395
Treponema pallidum fructose-bisphosphate aldolase 0.0187 0.0838 1
Echinococcus multilocularis cpg binding protein 0.012 0.052 0.0519
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0072 0.0293 0.2954
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0034 0.0115 0.0113
Trypanosoma cruzi cysteine peptidase, putative 0.0045 0.0165 0.0554
Loa Loa (eye worm) hypothetical protein 0.001 0.0002 0.0002
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0036 0.0124 0.0408
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0148 0.065 0.2283
Brugia malayi Cathepsin L-like precursor 0.0012 0.0009 0.0011
Trichomonas vaginalis phosphofructokinase, putative 0.0076 0.0313 0.1082
Echinococcus granulosus c src tyrosine kinase 0.0034 0.0115 0.0113
Echinococcus multilocularis chromobox protein 1 0.0045 0.0164 0.0163
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0016 0.0031 0.0031
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0036 0.0124 0.0147
Echinococcus multilocularis tyrosine protein kinase shark 0.0034 0.0115 0.0113
Leishmania major cathepsin L-like protease 0.0045 0.0165 0.0554
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0075 0.0235
Echinococcus granulosus chromobox protein 1 0.0045 0.0164 0.0163
Echinococcus granulosus neuropeptide s receptor 0.1146 0.5357 0.5356
Loa Loa (eye worm) hypothetical protein 0.0021 0.0052 0.0061
Loa Loa (eye worm) histone methyltransferase 0.0035 0.012 0.0143
Loa Loa (eye worm) hypothetical protein 0.0034 0.0115 0.0137
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0013 0.0014 0.0048
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.001 0.0003
Schistosoma mansoni hypothetical protein 0.0382 0.1755 0.1755
Loa Loa (eye worm) hypothetical protein 0.0022 0.0057 0.0068
Schistosoma mansoni microtubule-associated protein tau 0.213 1 1
Schistosoma mansoni hypothetical protein 0.0019 0.0042 0.0042
Schistosoma mansoni adapter molecule crk 0.0034 0.0115 0.0115
Echinococcus multilocularis tyrosine protein kinase Srms 0.0034 0.0115 0.0113
Brugia malayi Cathepsin L-like precursor 0.0012 0.0009 0.0011
Schistosoma mansoni lipoxygenase 0.0053 0.0203 0.0203
Schistosoma mansoni cpg binding protein 0.0114 0.049 0.049
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0028 0.0087 0.0085
Giardia lamblia Fructose-bisphosphate aldolase 0.0187 0.0838 0.2938
Onchocerca volvulus 0.0034 0.0115 0.1764
Echinococcus granulosus bloom syndrome protein 0.0013 0.0014 0.0012
Loa Loa (eye worm) cytochrome P450 family protein 0.002 0.0048 0.0057
Trypanosoma brucei protein kinase, putative 0.0036 0.0124 0.0405
Brugia malayi Tensin 0.0034 0.0115 0.0137
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.008 0.0331 0.0331
Entamoeba histolytica hypothetical protein, conserved 0.0607 0.2818 1
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0027 0.0081 0.1244
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0014 0.0019 0.0017
Trypanosoma cruzi PAB1-binding protein , putative 0.0041 0.0149 0.0499
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0034 0.0115 0.0113
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0072 0.0293 1
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0034 0.0115 0.0113
Onchocerca volvulus 0.0034 0.0115 0.1764
Entamoeba histolytica phosphofructokinase, putative 0.0076 0.0313 0.1082
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.008 0.0331 0.0331
Brugia malayi RNA recognition motif domain containing protein 0.0111 0.0476 0.0568
Brugia malayi RNA binding protein 0.0111 0.0476 0.0568
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0019 0.0042 0.004
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0187 0.0838 0.295
Loa Loa (eye worm) hypothetical protein 0.0034 0.0115 0.0137
Schistosoma mansoni tyrosine kinase 0.0034 0.0115 0.0115
Leishmania major mitochondrial DNA polymerase beta 0.0237 0.107 0.3776
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0075 0.0235
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0075 0.0235
Echinococcus multilocularis bloom syndrome protein 0.0013 0.0014 0.0012
Brugia malayi Heterochromatin protein 1 0.0045 0.0164 0.0196
Echinococcus granulosus expressed conserved protein 0.0034 0.0115 0.0113
Schistosoma mansoni DNA helicase recq5 0.0013 0.0014 0.0014
Echinococcus multilocularis growth factor receptor bound protein 2 0.0034 0.0115 0.0113
Echinococcus granulosus SHC transforming protein 3 0.0034 0.0115 0.0113
Trypanosoma cruzi polo-like protein kinase, putative 0.0148 0.065 0.2283
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0053 0.0158
Onchocerca volvulus 0.0013 0.0013 0.0207
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0014 0.0016
Loa Loa (eye worm) cytochrome P450 family protein 0.002 0.0048 0.0057
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.002 0.0048 0.0509
Brugia malayi Papain family cysteine protease containing protein 0.0012 0.0009 0.0011
Trichomonas vaginalis phosphofructokinase, putative 0.0021 0.0051 0.0149
Trypanosoma brucei cytochrome P450, putative 0.002 0.0048 0.0134
Echinococcus multilocularis musashi 0.0021 0.0053 0.0052
Brugia malayi hypothetical protein 0.0034 0.0115 0.0137
Trichomonas vaginalis phosphofructokinase, putative 0.0021 0.0051 0.0149
Plasmodium vivax ataxin-2 like protein, putative 0.0041 0.0149 0.4946
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0021 0.0051 0.0149
Trichomonas vaginalis hypothetical protein 0.0014 0.0019 0.0035
Echinococcus multilocularis chromobox protein 1 0.0045 0.0164 0.0163
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0034 0.0115 0.0113
Brugia malayi cytochrome P450 0.0014 0.0021 0.0025
Schistosoma mansoni suppressor of cytokine signaling 0.0034 0.0115 0.0115
Echinococcus granulosus tyrosine protein kinase Src42A 0.0034 0.0115 0.0113
Brugia malayi Protein kinase domain containing protein 0.0034 0.0115 0.0137
Brugia malayi Variant SH3 domain containing protein 0.0034 0.0115 0.0137
Loa Loa (eye worm) SH2 domain-containing protein 0.0034 0.0115 0.0137
Echinococcus granulosus cathepsin l1 0.0012 0.0009 0.0008
Loa Loa (eye worm) TK/ABL protein kinase 0.0034 0.0115 0.0137
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0028 0.0087 0.0085
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0035 0.012 0.0118
Trypanosoma brucei DNA repair and recombination helicase protein PIF7 0.0607 0.2818 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.008 0.0331 0.0331
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0036 0.0124 0.0405
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0187 0.0838 0.295
Echinococcus multilocularis lamin 0.0021 0.0053 0.0052
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0034 0.0115 0.0113
Leishmania major PIF1 helicase-like protein, putative,DNA repair and recombination protein, mitochondrial precursor, putative 0.0607 0.2818 1
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0095 0.0401 0.0399
Loa Loa (eye worm) hypothetical protein 0.002 0.0046 0.0055
Entamoeba histolytica phosphofructokinase, putative 0.0076 0.0313 0.1082
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0034 0.0115 0.0113
Loa Loa (eye worm) hypothetical protein 0.0034 0.0115 0.0137
Echinococcus multilocularis tensin 0.0034 0.0115 0.0113
Entamoeba histolytica hypothetical protein 0.0013 0.0017 0.0028
Loa Loa (eye worm) TK/FER protein kinase 0.0034 0.0115 0.0137
Brugia malayi RhoGAP domain containing protein 0.0034 0.0115 0.0137
Echinococcus multilocularis mitogen activated protein kinase 3 0.0036 0.0124 0.0122
Echinococcus multilocularis microtubule associated protein 2 0.213 1 1
Loa Loa (eye worm) ctsf protein 0.0012 0.0009 0.0011
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0034 0.0115 0.0113
Trichomonas vaginalis CAMK family protein kinase 0.0148 0.065 0.2283
Echinococcus multilocularis signal transduction protein lnk realted 0.0034 0.0115 0.0113
Echinococcus granulosus mixed lineage leukemia protein mll 0.0028 0.0087 0.0085
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0013 0.0014 0.0012
Echinococcus granulosus cpg binding protein 0.012 0.052 0.0519
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0012 0.0009 0.0008
Brugia malayi Cathepsin L-like precursor 0.0012 0.0009 0.0011
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0034 0.0115 0.0115
Trypanosoma cruzi PAB1-binding protein , putative 0.0041 0.0149 0.0499
Trichomonas vaginalis conserved hypothetical protein 0.0607 0.2818 1
Schistosoma mansoni hypothetical protein 0.0055 0.0215 0.0215
Plasmodium falciparum ataxin-2 like protein, putative 0.0041 0.0149 0.4946
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0034 0.0115 0.0137
Echinococcus granulosus cathepsin L cysteine proteinase 0.0012 0.0009 0.0008
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0034 0.0115 0.0113
Trichomonas vaginalis phosphofructokinase, putative 0.0021 0.0051 0.0149
Schistosoma mansoni tensin 0.0034 0.0115 0.0115

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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