Detailed information for compound 1006648

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 281.306 | Formula: C17H15NO3
  • H donors: 2 H acceptors: 3 LogP: 1.99 Rotable bonds: 0
    Rule of 5 violations (Lipinski): 1
  • SMILES: Oc1ccc2c(c1)/C=N/CCc1c(C(=O)C2)ccc(c1)O
  • InChi: 1S/C17H15NO3/c19-14-2-1-11-9-17(21)16-4-3-15(20)7-12(16)5-6-18-10-13(11)8-14/h1-4,7-8,10,19-20H,5-6,9H2/b18-10+
  • InChiKey: PNWFFHDUJSJLLU-VCHYOVAHSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus histone lysine methyltransferase setb 0.0078 0.07 0.1532
Leishmania major hypothetical protein, conserved 0.0078 0.0698 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0246 0.2679 0.5717
Brugia malayi Voltage-dependent L-type calcium channel beta-2 subunit 0.0304 0.3361 0.7173
Schistosoma mansoni lamin 0.0029 0.0122 0.0267
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.0221 0.0221
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0221 0.0221
Echinococcus granulosus lysine specific demethylase 6a 0.0038 0.0237 0.0519
Trypanosoma brucei unspecified product 0.0021 0.0026 0.0372
Schistosoma mansoni sodium/chloride dependent transporter 0.0077 0.0688 0.1505
Brugia malayi Calcitonin receptor-like protein seb-1 0.0051 0.0387 0.0826
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0021 0.0026 0.0026
Brugia malayi Bromodomain containing protein 0.0038 0.0233 0.0497
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0221 0.0221
Brugia malayi ImpB/MucB/SamB family protein 0.0048 0.0344 0.0735
Brugia malayi Intermediate filament tail domain containing protein 0.0029 0.0122 0.026
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0026 0.0372
Schistosoma mansoni protein phosphatase 2C 0.0038 0.0237 0.0519
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0102 0.0102
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0055 0.0434 0.095
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0026 0.0372
Toxoplasma gondii PHD-finger domain-containing protein 0.0039 0.0243 0.2047
Leishmania major hypothetical protein, conserved 0.0038 0.0237 0.3401
Echinococcus multilocularis jumonji domain containing 1A 0.0038 0.0237 0.0519
Loa Loa (eye worm) jmjC domain-containing protein 0.0038 0.0237 0.0506
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0077 0.0688 0.1468
Schistosoma mansoni inositol monophosphatase 0.0039 0.0246 0.0539
Echinococcus granulosus jumonji domain containing protein 0.0166 0.1735 0.3799
Schistosoma mansoni DNA polymerase eta 0.0048 0.0344 0.0754
Schistosoma mansoni bromodomain containing protein 0.0066 0.0563 0.1232
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0417 0.4686 1
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0066 0.0066
Echinococcus granulosus dnaJ subfamily B 0.0407 0.4568 1
Echinococcus granulosus neutral alpha glucosidase AB 0.0037 0.0221 0.0485
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0094 0.0885 0.1938
Brugia malayi follicle stimulating hormone receptor 0.0248 0.2707 0.5776
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0078 0.07 0.1532
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0066 0.0066
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0026 0.0372
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0039 0.0243 0.3483
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0869 1 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0233 0.0497
Echinococcus multilocularis lysine specific demethylase 5A 0.0144 0.1481 0.3243
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0102 0.0102
Brugia malayi chromobox protein homolog 3 0.0038 0.0233 0.0497
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0066 0.0066
Trypanosoma brucei PAB1-binding protein , putative 0.0078 0.0698 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0026 0.0372
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0246 0.3532
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0094 0.0885 0.1938
Brugia malayi Glycosyl hydrolases family 31 protein 0.0167 0.1752 0.374
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0038 0.0237 0.0519
Schistosoma mansoni alpha-glucosidase 0.0144 0.1478 0.3236
Loa Loa (eye worm) hypothetical protein 0.007 0.0612 0.1306
Echinococcus granulosus cpg binding protein 0.0062 0.051 0.1117
Trypanosoma cruzi PAB1-binding protein , putative 0.0078 0.0698 1
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0026 0.0372
Schistosoma mansoni lamin 0.0029 0.0122 0.0267
Plasmodium vivax hypothetical protein, conserved 0.0119 0.1186 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0237 0.0506
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0026 0.0372
Loa Loa (eye worm) histone methyltransferase 0.002 0.0016 0.0035
Echinococcus multilocularis cpg binding protein 0.0062 0.051 0.1117
Onchocerca volvulus 0.0474 0.5361 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0026 0.0372
Schistosoma mansoni terminal deoxycytidyl transferase 0.0021 0.0026 0.0057
Giardia lamblia Fructose-bisphosphate aldolase 0.0869 1 1
Schistosoma mansoni chromobox protein 0.0068 0.0584 0.1278
Loa Loa (eye worm) PHD-finger family protein 0.0119 0.1186 0.2532
Toxoplasma gondii PHD-finger domain-containing protein 0.0119 0.1186 1
Onchocerca volvulus 0.0072 0.0631 0.0972
Toxoplasma gondii PHD-finger domain-containing protein 0.0119 0.1186 1
Trichomonas vaginalis maltase-glucoamylase, putative 0.0037 0.0221 0.0221
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0039 0.0246 1
Treponema pallidum fructose-bisphosphate aldolase 0.0869 1 1
Echinococcus multilocularis chromobox protein 1 0.0068 0.0584 0.1278
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0044 0.0297 0.0651
Echinococcus multilocularis high voltage activated calcium channel beta 0.0148 0.152 0.3328
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0066 0.0066
Echinococcus multilocularis lamin dm0 0.0029 0.0122 0.0267
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0026 0.0056
Brugia malayi jmjC domain containing protein 0.0038 0.0237 0.0506
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.039 0.4376 0.9578
Onchocerca volvulus 0.0097 0.0923 0.1529
Schistosoma mansoni cpg binding protein 0.0062 0.051 0.1117
Schistosoma mansoni hypothetical protein 0.0021 0.0026 0.0057
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0221 0.3174
Schistosoma mansoni cpg binding protein 0.0057 0.045 0.0985
Echinococcus multilocularis sodium and chloride dependent glycine 0.0077 0.0688 0.1505
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0094 0.0885 0.1938
Echinococcus multilocularis chromobox protein 1 0.0068 0.0584 0.1278
Brugia malayi Bromodomain containing protein 0.0078 0.07 0.1493
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0267 0.0277
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0246 0.3532
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0026 0.0372
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0061 0.05 0.1095
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0869 1 1
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0077 0.0688 0.1468
Echinococcus multilocularis zinc finger protein 0.0023 0.0052 0.0113
Plasmodium vivax ataxin-2 like protein, putative 0.0078 0.0698 0.5879
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0869 1 1
Echinococcus granulosus chromobox protein 1 0.0068 0.0584 0.1278
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0035 0.0198 0.0415
Loa Loa (eye worm) hypothetical protein 0.0035 0.0196 0.0419
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0035 0.0194 0.0425
Brugia malayi PHD-finger family protein 0.0028 0.0114 0.0243
Brugia malayi Inositol-1 0.0039 0.0246 0.0526
Brugia malayi AF-10 protein 0.0039 0.0243 0.0518
Brugia malayi PHD-finger family protein 0.0119 0.1186 0.2532
Schistosoma mansoni cpg binding protein 0.0062 0.051 0.1117
Leishmania major alpha glucosidase II subunit, putative 0.0037 0.0221 0.3174
Loa Loa (eye worm) CXXC zinc finger family protein 0.0057 0.045 0.096
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0037 0.0221 0.1866
Loa Loa (eye worm) heterochromatin protein 1 0.0068 0.0584 0.1246
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0221 0.0221
Echinococcus multilocularis dna polymerase kappa 0.0021 0.0026 0.0057
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0221 0.0221
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0026 0.0054
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0038 0.0237 0.1999
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0061 0.05 0.4216
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0021 0.0026 0.0057
Echinococcus granulosus dna polymerase eta 0.0048 0.0344 0.0754
Echinococcus granulosus tumor protein p63 0.0328 0.3642 0.7973
Echinococcus multilocularis tumor protein p63 0.0328 0.3642 0.7973
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0066 0.0066
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0072 0.0631 0.1381
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0094 0.0885 0.1938
Echinococcus granulosus high voltage activated calcium channel beta 0.0148 0.152 0.3328
Loa Loa (eye worm) hypothetical protein 0.0038 0.0234 0.0498
Brugia malayi hypothetical protein 0.005 0.0374 0.0798
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0424 0.4775 1
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0036 0.0205 0.0449
Echinococcus multilocularis dnaJ subfamily B 0.0407 0.4568 1
Loa Loa (eye worm) hypothetical protein 0.0078 0.0698 0.1488
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0026 0.0054
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0066 0.0066
Toxoplasma gondii LsmAD domain-containing protein 0.0078 0.0698 0.5879
Loa Loa (eye worm) hypothetical protein 0.0028 0.0116 0.0247
Loa Loa (eye worm) hypothetical protein 0.0051 0.0387 0.0826
Schistosoma mansoni phd/f-box containing protein 0.0038 0.0237 0.0519
Schistosoma mansoni intermediate filament proteins 0.0029 0.0122 0.0267
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.002 0.0016 0.0036
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0869 1 1
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0039 0.0243 0.2047
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0349 0.0765
Echinococcus multilocularis lysosomal alpha glucosidase 0.0167 0.1752 0.3836
Trypanosoma cruzi DNA polymerase eta, putative 0.0048 0.0344 0.4936
Echinococcus multilocularis jumonji domain containing protein 0.0166 0.1735 0.3799
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0038 0.0237 0.3401
Loa Loa (eye worm) hypothetical protein 0.0038 0.0237 0.0506
Echinococcus multilocularis dna polymerase eta 0.0048 0.0344 0.0754
Echinococcus granulosus jumonji domain containing 1A 0.0038 0.0237 0.0519
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0248 0.2707 0.5776
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.0221 0.0221
Trypanosoma brucei DNA polymerase eta, putative 0.0048 0.0344 0.4936
Loa Loa (eye worm) hypothetical protein 0.0078 0.07 0.1493
Plasmodium vivax SET domain protein, putative 0.0061 0.05 0.4216
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0078 0.07 0.1532
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0078 0.07 0.1532
Schistosoma mansoni hypothetical protein 0.0119 0.1186 0.2597
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0119 0.1186 0.2597
Echinococcus multilocularis lysine specific demethylase 6a 0.0038 0.0237 0.0519
Schistosoma mansoni hypothetical protein 0.0407 0.4568 1
Schistosoma mansoni jumonji domain containing protein 0.031 0.3432 0.7513
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0267 0.0267
Schistosoma mansoni high voltage-activated calcium channel beta subunit 2 0.0148 0.152 0.3328
Trichomonas vaginalis sucrase-isomaltase, putative 0.0037 0.0221 0.0221
Echinococcus granulosus sodium and chloride dependent glycine 0.0077 0.0688 0.1505
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0021 0.0026 0.0057
Onchocerca volvulus 0.0048 0.0349 0.0434
Brugia malayi Bromodomain containing protein 0.0122 0.1214 0.2591
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.0246 0.0246
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0869 1 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0869 1 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0094 0.0885 0.1938
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0039 0.0246 0.0246
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0035 0.0194 0.0425
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0039 0.0246 0.2076
Schistosoma mansoni sodium/chloride dependent transporter 0.0077 0.0688 0.1505
Loa Loa (eye worm) hypothetical protein 0.0048 0.0344 0.0735
Echinococcus multilocularis musashi 0.0029 0.0122 0.0267
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0026 0.0372
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0094 0.0885 0.1938
Echinococcus granulosus chromobox protein 1 0.0068 0.0584 0.1278
Echinococcus multilocularis inositol monophosphatase 1 0.0039 0.0246 0.0539
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0021 0.0026 0.0055
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0057 0.046 0.1007
Schistosoma mansoni chromobox protein 0.0068 0.0584 0.1278
Schistosoma mansoni phosphatidylserine receptor 0.0038 0.0237 0.0519
Loa Loa (eye worm) hypothetical protein 0.0204 0.2188 0.4669
Echinococcus multilocularis peregrin 0.0122 0.1214 0.2658
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.0246 0.0246
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0267 0.0267
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0038 0.0237 0.3401
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0424 0.4775 1
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0233 0.0233
Schistosoma mansoni jumonji/arid domain-containing protein 0.0149 0.1542 0.3375
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0026 0.0372
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.05 0.1095
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0037 0.0221 0.0472
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0036 0.0205 0.0449
Echinococcus multilocularis PHD finger protein rhinoceros 0.0119 0.1186 0.2597
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0221 0.0221
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0167 0.1752 0.374
Loa Loa (eye worm) intermediate filament protein 0.0029 0.0122 0.026
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0026 0.0372
Loa Loa (eye worm) hypothetical protein 0.0077 0.0688 0.1468
Loa Loa (eye worm) hypothetical protein 0.003 0.0136 0.029
Loa Loa (eye worm) voltage-dependent calcium channel beta 2a subunit 0.0304 0.3361 0.7173
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0094 0.0885 0.1938
Giardia lamblia DINP protein human, muc B family 0.0021 0.0026 0.0026
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0424 0.4775 1
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0094 0.0885 0.1889
Echinococcus multilocularis neutral alpha glucosidase AB 0.0037 0.0221 0.0485
Loa Loa (eye worm) hypothetical protein 0.0077 0.0688 0.1468
Echinococcus granulosus intermediate filament protein 0.0029 0.0122 0.0267
Plasmodium vivax JmjC domain containing protein 0.0038 0.0237 0.1999
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0221 0.3174
Giardia lamblia PHD finger protein 15 0.0119 0.1186 0.1186
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0246 0.3532
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0094 0.0885 0.1889
Toxoplasma gondii histone lysine methyltransferase SET1 0.0112 0.1099 0.926
Brugia malayi jmjC domain containing protein 0.0038 0.0237 0.0506
Brugia malayi latrophilin 2 splice variant baaae 0.0035 0.0196 0.0419
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0026 0.0372
Brugia malayi jmjC domain containing protein 0.0038 0.0237 0.0506
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0026 0.0086 0.0189
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0029 0.0122 0.026
Loa Loa (eye worm) hypothetical protein 0.0048 0.0349 0.0746
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0026 0.0054
Loa Loa (eye worm) hypothetical protein 0.0119 0.1186 0.2532
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0869 1 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0066 0.0066
Leishmania major DNA polymerase eta, putative 0.0048 0.0344 0.4936
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0246 0.3532
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0044 0.0297 0.0651
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0039 0.0243 0.3483
Loa Loa (eye worm) jmjC domain-containing protein 0.0038 0.0237 0.0506
Loa Loa (eye worm) jmjC domain-containing protein 0.0149 0.1542 0.329
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0038 0.0237 0.3401
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0021 0.0026 0.0372
Echinococcus granulosus inositol monophosphatase 1 0.0039 0.0246 0.0539
Schistosoma mansoni hypothetical protein 0.0039 0.0243 0.0532
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0021 0.0026 0.0057
Brugia malayi jmjC domain containing protein 0.0149 0.1542 0.329
Loa Loa (eye worm) hypothetical protein 0.0046 0.0321 0.0686
Trichomonas vaginalis set domain proteins, putative 0.0474 0.5361 0.5361
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0026 0.0372
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0026 0.0372
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0039 0.0246 0.0516
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0026 0.0086 0.0189
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0033 0.0178 0.15
Echinococcus multilocularis lysosomal alpha glucosidase 0.0167 0.1752 0.3836
Echinococcus granulosus JmjC domain containing protein 4 0.0038 0.0237 0.0519
Trypanosoma cruzi PAB1-binding protein , putative 0.0078 0.0698 1
Brugia malayi Glycosyl hydrolases family 31 protein 0.0037 0.0221 0.0472
Brugia malayi jmjC domain containing protein 0.039 0.4376 0.9337
Loa Loa (eye worm) hypothetical protein 0.0029 0.0122 0.026
Echinococcus granulosus zinc finger protein 0.0023 0.0052 0.0113
Echinococcus granulosus lamin dm0 0.0029 0.0122 0.0267
Brugia malayi F/Y-rich N-terminus family protein 0.006 0.0494 0.1055
Trypanosoma brucei glucosidase, putative 0.0037 0.0221 0.3174
Trichomonas vaginalis DNA polymerase eta, putative 0.0021 0.0026 0.0026
Brugia malayi Pre-SET motif family protein 0.0417 0.4686 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0038 0.0237 0.0506
Loa Loa (eye worm) hypothetical protein 0.0041 0.0261 0.0557
Schistosoma mansoni inositol monophosphatase 0.0039 0.0246 0.0539
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0221 0.0221
Echinococcus granulosus fetal alzheimer antigen falz 0.0026 0.0086 0.0189
Schistosoma mansoni zinc finger protein 0.0023 0.0052 0.0113
Onchocerca volvulus 0.003 0.0136 0.0027
Trichomonas vaginalis inositol monophosphatase, putative 0.0039 0.0246 0.0246
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0221 0.0221
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.002 0.0016 0.0036
Echinococcus granulosus sodium and chloride dependent glycine 0.0077 0.0688 0.1505
Plasmodium falciparum ataxin-2 like protein, putative 0.0078 0.0698 0.5879
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0042 0.0283 0.2389
Leishmania major DNA polymerase kappa, putative 0.0021 0.0026 0.0372
Schistosoma mansoni hypothetical protein 0.0035 0.0196 0.043
Brugia malayi Pre-SET motif family protein 0.0061 0.05 0.1068
Echinococcus multilocularis phd:f box containing protein 0.0038 0.0237 0.0519
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0026 0.0372
Schistosoma mansoni alpha-glucosidase 0.0144 0.1478 0.3236
Plasmodium falciparum JmjC domain-containing protein, putative 0.0038 0.0237 0.1999
Echinococcus multilocularis sodium and chloride dependent glycine 0.0077 0.0688 0.1505
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0869 1 1
Echinococcus granulosus lysine specific demethylase 5A 0.0149 0.1542 0.3375
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0038 0.0237 0.1999
Echinococcus granulosus lamin 0.0029 0.0122 0.0267
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0051 0.0387 0.0826
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0066 0.0066
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0869 1 1
Onchocerca volvulus Alhambra homolog 0.0119 0.1186 0.2032
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.039 0.4376 0.9578
Brugia malayi PHD-finger family protein 0.0044 0.0303 0.0647
Plasmodium falciparum ataxin-2 like protein, putative 0.0078 0.0698 0.5879
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0051 0.0387 0.0826
Plasmodium vivax hypothetical protein, conserved 0.0042 0.0283 0.2389
Brugia malayi CXXC zinc finger family protein 0.0057 0.045 0.096
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0584 0.0584
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0021 0.0026 0.0054
Loa Loa (eye worm) hypothetical protein 0.0044 0.0303 0.0647
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0233 0.0233
Entamoeba histolytica deoxycytidyl transferase, putative 0.0021 0.0026 0.0026
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0063 0.0521 0.114
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0026 0.0372
Trypanosoma cruzi DNA polymerase eta, putative 0.0033 0.0178 0.2551
Plasmodium falciparum phd finger protein, putative 0.0119 0.1186 1
Echinococcus multilocularis JmjC domain containing protein 4 0.0038 0.0237 0.0519
Echinococcus granulosus PHD finger protein rhinoceros 0.0119 0.1186 0.2597
Brugia malayi jmjC domain containing protein 0.0038 0.0237 0.0506
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0584 0.0584
Schistosoma mansoni hypothetical protein 0.0035 0.0194 0.0425
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0122 0.1222 0.2674
Onchocerca volvulus 0.0057 0.045 0.0626
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0063 0.0521 0.114
Brugia malayi intermediate filament protein 0.0029 0.0122 0.026
Brugia malayi Heterochromatin protein 1 0.0068 0.0584 0.1246
Schistosoma mansoni jumonji/arid domain-containing protein 0.0149 0.1542 0.3375
Echinococcus granulosus dna polymerase kappa 0.0021 0.0026 0.0057
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0026 0.0055
Leishmania major DNA polymerase eta, putative 0.0033 0.0178 0.2551
Brugia malayi hypothetical protein 0.0078 0.0698 0.1488
Schistosoma mansoni alpha glucosidase 0.0037 0.0221 0.0485
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0038 0.0233 0.0212
Echinococcus multilocularis lamin 0.0029 0.0122 0.0267
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0026 0.0372
Loa Loa (eye worm) inositol-1 0.0039 0.0246 0.0526
Echinococcus granulosus lysosomal alpha glucosidase 0.0167 0.1752 0.3836
Echinococcus granulosus peregrin 0.0122 0.1214 0.2658
Echinococcus granulosus phd:f box containing protein 0.0038 0.0237 0.0519
Schistosoma mansoni jumonji domain containing protein 0.0038 0.0237 0.0519

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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