Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.001 | 0.0022 | 0.0022 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.001 | 0.0022 | 0.0028 |
Brugia malayi | CXXC zinc finger family protein | 0.0029 | 0.0231 | 0.027 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.003 | 0.0241 | 0.0306 |
Echinococcus multilocularis | FTZ F1 alpha | 0.001 | 0.0022 | 0.0022 |
Brugia malayi | RNA binding protein | 0.0068 | 0.0673 | 0.0833 |
Echinococcus granulosus | GPCR family 2 | 0.0031 | 0.0253 | 0.0321 |
Schistosoma mansoni | hypothetical protein | 0.0066 | 0.0653 | 0.0829 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0022 | 0.0023 |
Brugia malayi | Cytochrome P450 family protein | 0.0019 | 0.0119 | 0.0129 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.0022 | 0.0028 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.0022 | 0.0004 |
Loa Loa (eye worm) | steroid hormone receptor | 0.001 | 0.0022 | 0.0023 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.001 | 0.0022 | 0.0004 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.001 | 0.0022 | 0.0028 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0072 | 0.0714 | 0.0879 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0035 | 0.0303 | 0.0362 |
Toxoplasma gondii | ABC1 family protein | 0.0072 | 0.0714 | 0.0879 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0035 | 0.0303 | 0.0303 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.0022 | 0.0022 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.001 | 0.0022 | 0.0004 |
Schistosoma mansoni | hypothetical protein | 0.041 | 0.4509 | 0.5725 |
Trypanosoma cruzi | glycosyl hydrolase-like protein, putative | 0.0013 | 0.0055 | 0.004 |
Schistosoma mansoni | hypothetical protein | 0.0188 | 0.2017 | 0.2561 |
Loa Loa (eye worm) | hypothetical protein | 0.071 | 0.7875 | 1 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0146 | 0.1545 | 0.1961 |
Onchocerca volvulus | 0.0072 | 0.0714 | 0.0881 | |
Leishmania major | eukaryotic initiation factor 4a, putative | 0.071 | 0.7875 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0188 | 0.2017 | 0.2561 |
Echinococcus multilocularis | eukaryotic initiation factor 4A | 0.071 | 0.7875 | 0.7875 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0146 | 0.1545 | 0.1942 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0035 | 0.0303 | 0.0355 |
Brugia malayi | Pre-SET motif family protein | 0.0203 | 0.2189 | 0.2763 |
Leishmania major | hypothetical protein, conserved | 0.0028 | 0.0221 | 0.0252 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.0022 | 0.0004 |
Schistosoma mansoni | nuclear hormone receptor | 0.001 | 0.0022 | 0.0028 |
Treponema pallidum | ATP-dependent RNA helicase | 0.071 | 0.7875 | 0.5 |
Leishmania major | eukaryotic initiation factor 4a, putative | 0.071 | 0.7875 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.0022 | 0.0004 |
Trypanosoma cruzi | Eukaryotic initiation factor 4A-1 | 0.071 | 0.7875 | 1 |
Onchocerca volvulus | 0.0092 | 0.0937 | 0.1165 | |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0035 | 0.0303 | 0.0317 |
Brugia malayi | eukaryotic initiation factor 4A | 0.071 | 0.7875 | 1 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.001 | 0.0022 | 0.0028 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.0022 | 0.0028 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0043 | 0.0389 | 0.0219 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.001 | 0.0022 | 0.0022 |
Schistosoma mansoni | DEAD box ATP-dependent RNA helicase | 0.071 | 0.7875 | 1 |
Brugia malayi | Cytochrome P450 family protein | 0.001 | 0.0024 | 0.0007 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0072 | 0.0714 | 0.0843 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.001 | 0.0022 | 0.0004 |
Schistosoma mansoni | hypothetical protein | 0.0013 | 0.0048 | 0.0062 |
Echinococcus granulosus | geminin | 0.0188 | 0.2017 | 0.2561 |
Schistosoma mansoni | hypothetical protein | 0.001 | 0.0024 | 0.003 |
Mycobacterium tuberculosis | Conserved protein | 0.0072 | 0.0714 | 0.0879 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0022 | 0.0023 |
Onchocerca volvulus | 0.0231 | 0.2504 | 0.316 | |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0031 | 0.0253 | 0.0321 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0013 | 0.0055 | 0.0046 |
Onchocerca volvulus | 0.0072 | 0.0714 | 0.0881 | |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0241 | 0.0306 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0142 | 0.1501 | 0.1907 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0253 | 0.0321 |
Brugia malayi | nuclear hormone receptor | 0.001 | 0.0022 | 0.0004 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0035 | 0.0303 | 0.0317 |
Trypanosoma brucei | Eukaryotic initiation factor 4A-1 | 0.071 | 0.7875 | 1 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0019 | 0.0119 | 0.0147 |
Mycobacterium ulcerans | beta-lactamase | 0.0072 | 0.0714 | 1 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0159 | 0.1688 | 0.1688 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0072 | 0.0714 | 0.0903 |
Echinococcus granulosus | FTZ F1 alpha | 0.001 | 0.0022 | 0.0028 |
Mycobacterium tuberculosis | Probable cold-shock DeaD-box protein A homolog DeaD (ATP-dependent RNA helicase dead homolog) | 0.071 | 0.7875 | 1 |
Leishmania major | cytochrome p450-like protein | 0.0019 | 0.0119 | 0.0122 |
Loa Loa (eye worm) | acetyltransferase | 0.0146 | 0.1545 | 0.1958 |
Brugia malayi | hypothetical protein | 0.004 | 0.0356 | 0.0429 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.001 | 0.0022 | 0.0028 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0097 | 0.0998 | 0.1263 |
Echinococcus multilocularis | 0.001 | 0.0024 | 0.0024 | |
Schistosoma mansoni | transcription factor LCR-F1 | 0.004 | 0.0356 | 0.0451 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.001 | 0.0022 | 0.0023 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.001 | 0.0022 | 0.0022 |
Onchocerca volvulus | Eukaryotic initiation factor 4A homolog | 0.071 | 0.7875 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0097 | 0.0998 | 0.1263 |
Mycobacterium ulcerans | hypothetical protein | 0.0072 | 0.0714 | 1 |
Schistosoma mansoni | alpha-glucosidase | 0.0137 | 0.144 | 0.1828 |
Schistosoma mansoni | tar DNA-binding protein | 0.0068 | 0.0673 | 0.0854 |
Trypanosoma cruzi | glycosyl hydrolase-like protein, putative | 0.0013 | 0.0055 | 0.004 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0031 | 0.0253 | 0.0253 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0142 | 0.1499 | 0.1903 |
Leishmania major | glycosyl hydrolase-like protein | 0.0013 | 0.0055 | 0.004 |
Trichomonas vaginalis | DEAD box ATP-dependent RNA helicase, putative | 0.071 | 0.7875 | 1 |
Onchocerca volvulus | 0.0029 | 0.0231 | 0.0266 | |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0221 | 0.0277 |
Echinococcus granulosus | eukaryotic initiation factor 4A III | 0.071 | 0.7875 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0142 | 0.1501 | 0.1501 |
Mycobacterium tuberculosis | Conserved protein | 0.0072 | 0.0714 | 0.0879 |
Loa Loa (eye worm) | histone methyltransferase | 0.001 | 0.002 | 0.0021 |
Echinococcus multilocularis | geminin | 0.0188 | 0.2017 | 0.2017 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.001 | 0.0022 | 0.0022 |
Brugia malayi | ecdysteroid receptor | 0.001 | 0.0022 | 0.0004 |
Entamoeba histolytica | hypothetical protein | 0.004 | 0.0356 | 0.0384 |
Mycobacterium leprae | Probable lipase LipE | 0.0072 | 0.0714 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.001 | 0.0022 | 0.0023 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.001 | 0.0022 | 0.0004 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0159 | 0.1688 | 0.2139 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0072 | 0.0714 | 0.0843 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0072 | 0.0714 | 0.0907 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.001 | 0.0022 | 0.0028 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0072 | 0.0714 | 0.0885 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0035 | 0.0303 | 0.0317 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0159 | 0.1688 | 0.2125 |
Mycobacterium ulcerans | lipase LipD | 0.0072 | 0.0714 | 1 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.001 | 0.0022 | 0.0028 |
Onchocerca volvulus | 0.003 | 0.0241 | 0.0279 | |
Entamoeba histolytica | hypothetical protein | 0.004 | 0.0356 | 0.0384 |
Loa Loa (eye worm) | beta-lactamase | 0.0072 | 0.0714 | 0.0903 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0043 | 0.0389 | 0.0494 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0035 | 0.0303 | 0.0317 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0249 | 0.0316 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0022 | 0.0023 |
Trichomonas vaginalis | DEAD box ATP-dependent RNA helicase, putative | 0.071 | 0.7875 | 1 |
Entamoeba histolytica | hypothetical protein | 0.004 | 0.0356 | 0.0384 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0066 | 0.0653 | 0.0808 |
Brugia malayi | hypothetical protein | 0.0028 | 0.0221 | 0.0258 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0072 | 0.0714 | 0.0879 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0022 | 0.0023 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0022 | 0.0023 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0714 | 0.0903 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0072 | 0.0714 | 0.0879 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0022 | 0.0023 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.001 | 0.0022 | 0.0028 |
Echinococcus multilocularis | cpg binding protein | 0.003 | 0.0249 | 0.0249 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0039 | 0.0349 | 0.0376 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0028 | 0.0221 | 0.0252 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0035 | 0.0303 | 0.0317 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.001 | 0.0022 | 0.0028 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0072 | 0.0714 | 0.0907 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.0022 | 0.0028 |
Onchocerca volvulus | 0.0072 | 0.0714 | 0.0881 | |
Loa Loa (eye worm) | TAR-binding protein | 0.0068 | 0.0673 | 0.085 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.003 | 0.0241 | 0.0241 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0142 | 0.1501 | 0.1907 |
Leishmania major | hypothetical protein, conserved | 0.0072 | 0.0714 | 0.0879 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0019 | 0.0119 | 0.0122 |
Echinococcus multilocularis | dnaJ subfamily B | 0.041 | 0.4509 | 0.4509 |
Mycobacterium tuberculosis | Conserved protein | 0.0072 | 0.0714 | 0.0879 |
Schistosoma mansoni | alpha glucosidase | 0.0035 | 0.0303 | 0.0384 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0356 | 0.0451 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0714 | 0.0903 |
Brugia malayi | beta-lactamase | 0.0072 | 0.0714 | 0.0885 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.0022 | 0.0022 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0072 | 0.0714 | 0.0879 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.0022 | 0.0004 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0142 | 0.1501 | 0.1501 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0019 | 0.0119 | 0.0147 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0.0303 | 0.0355 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0.0303 | 0.0355 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0459 | 0.506 | 0.6414 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.003 | 0.0241 | 0.0306 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0241 | 0.0302 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0019 | 0.0119 | 0.0147 |
Brugia malayi | Cytochrome P450 family protein | 0.0029 | 0.0232 | 0.0272 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0142 | 0.1501 | 0.1907 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0043 | 0.0389 | 0.0465 |
Brugia malayi | nuclear receptor NHR-88 | 0.001 | 0.0022 | 0.0004 |
Echinococcus multilocularis | eukaryotic initiation factor 4A III | 0.071 | 0.7875 | 0.7875 |
Schistosoma mansoni | DEAD box ATP-dependent RNA helicase | 0.071 | 0.7875 | 1 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.004 | 0.0356 | 0.0451 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0029 | 0.0231 | 0.0289 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.0022 | 0.0022 |
Plasmodium vivax | RNA helicase-1, putative | 0.071 | 0.7875 | 1 |
Brugia malayi | Pre-SET motif family protein | 0.003 | 0.0241 | 0.0283 |
Brugia malayi | beta-lactamase family protein | 0.0072 | 0.0714 | 0.0885 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0072 | 0.0714 | 0.0879 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0072 | 0.0714 | 0.0879 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.001 | 0.0022 | 0.0028 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0097 | 0.0998 | 0.1247 |
Echinococcus multilocularis | GPCR, family 2 | 0.0031 | 0.0253 | 0.0253 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0714 | 0.0903 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0035 | 0.0303 | 0.0317 |
Echinococcus multilocularis | tar DNA binding protein | 0.0068 | 0.0673 | 0.0673 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.001 | 0.0022 | 0.0023 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.0022 | 0.0028 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0028 | 0.0221 | 0.0252 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0031 | 0.0253 | 0.0317 |
Brugia malayi | Cytochrome P450 family protein | 0.0019 | 0.0119 | 0.0129 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.001 | 0.0022 | 0.0004 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.0022 | 0.0004 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.001 | 0.0022 | 0.0023 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0068 | 0.0673 | 0.0833 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0013 | 0.0048 | 0.0062 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0029 | 0.0232 | 0.0291 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0043 | 0.0389 | 0.0427 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.001 | 0.002 | 0.002 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0714 | 0.0903 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0072 | 0.0714 | 0.0879 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.0022 | 0.0022 |
Schistosoma mansoni | tar DNA-binding protein | 0.0068 | 0.0673 | 0.0854 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0035 | 0.0303 | 0.0317 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.001 | 0.0022 | 0.0023 |
Brugia malayi | TAR-binding protein | 0.0068 | 0.0673 | 0.0833 |
Loa Loa (eye worm) | RNA binding protein | 0.0068 | 0.0673 | 0.085 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0714 | 0.0903 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0068 | 0.0673 | 0.085 |
Onchocerca volvulus | Uncharacterized family 31 glucosidase KIAA1161 homolog | 0.0013 | 0.0055 | 0.0042 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.001 | 0.0022 | 0.0028 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0714 | 0.0903 |
Plasmodium vivax | SET domain protein, putative | 0.003 | 0.0241 | 0.0026 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.001 | 0.002 | 0.0025 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0146 | 0.1545 | 0.1545 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0072 | 0.0714 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0142 | 0.1501 | 0.1907 |
Trypanosoma cruzi | Eukaryotic initiation factor 4A-1 | 0.071 | 0.7875 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0055 | 0.0065 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.001 | 0.0022 | 0.0023 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0013 | 0.0048 | 0.0048 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.001 | 0.0022 | 0.0004 |
Plasmodium falciparum | eukaryotic initiation factor 4A | 0.071 | 0.7875 | 1 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.001 | 0.0022 | 0.0028 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0035 | 0.0303 | 0.0317 |
Trichomonas vaginalis | DEAD box ATP-dependent RNA helicase, putative | 0.071 | 0.7875 | 1 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0035 | 0.0303 | 0.0317 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0022 | 0.0023 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0022 | 0.0023 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0253 | 0.0321 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0043 | 0.0389 | 0.0465 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0062 | 0.0605 | 0.0768 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0019 | 0.0119 | 0.0122 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0072 | 0.0714 | 0.0879 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0039 | 0.0349 | 0.0167 |
Trypanosoma brucei | glycosyl hydrolase-like protein | 0.0013 | 0.0055 | 0.004 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0072 | 0.0714 | 0.0843 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0072 | 0.0714 | 0.0843 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.001 | 0.0022 | 0.0004 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0142 | 0.1501 | 0.1907 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.0231 | 0.0293 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0028 | 0.0221 | 0.0252 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0035 | 0.0303 | 0.0317 |
Brugia malayi | hypothetical protein | 0.0018 | 0.011 | 0.0117 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0072 | 0.0714 | 0.0907 |
Trypanosoma brucei | cytochrome P450, putative | 0.0019 | 0.0119 | 0.0122 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.004 | 0.0356 | 0.0356 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0072 | 0.0714 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0241 | 0.0306 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0035 | 0.0303 | 0.038 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0253 | 0.0321 |
Brugia malayi | cytochrome P450 | 0.001 | 0.0024 | 0.0007 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0035 | 0.0303 | 0.0355 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0019 | 0.0119 | 0.1386 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0072 | 0.0714 | 0.0879 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.001 | 0.0022 | 0.0004 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0072 | 0.0714 | 0.0843 |
Entamoeba histolytica | hypothetical protein | 0.004 | 0.0356 | 0.0384 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.001 | 0.0022 | 0.0004 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0031 | 0.0253 | 0.0298 |
Plasmodium vivax | hypothetical protein, conserved | 0.0072 | 0.0714 | 0.0644 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0142 | 0.1501 | 0.1903 |
Mycobacterium leprae | conserved hypothetical protein | 0.0072 | 0.0714 | 1 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.001 | 0.0022 | 0.0028 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0031 | 0.0253 | 0.0321 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0028 | 0.0221 | 0.0252 |
Trichomonas vaginalis | set domain proteins, putative | 0.0231 | 0.2504 | 0.3131 |
Echinococcus granulosus | tar DNA binding protein | 0.0068 | 0.0673 | 0.0854 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0142 | 0.1501 | 0.1888 |
Trichomonas vaginalis | esterase, putative | 0.0072 | 0.0714 | 0.0843 |
Giardia lamblia | Translation initiation factor eIF-4A, putative | 0.071 | 0.7875 | 1 |
Schistosoma mansoni | cytochrome P450 | 0.001 | 0.0024 | 0.003 |
Echinococcus granulosus | dnaJ subfamily B | 0.041 | 0.4509 | 0.5725 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0072 | 0.0714 | 0.0714 |
Schistosoma mansoni | tar DNA-binding protein | 0.0068 | 0.0673 | 0.0854 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0203 | 0.2189 | 0.2777 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0097 | 0.0998 | 0.1247 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.0022 | 0.0028 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0031 | 0.0253 | 0.0253 |
Echinococcus granulosus | cpg binding protein | 0.003 | 0.0249 | 0.0316 |
Entamoeba histolytica | DEAD/DEAH box helicase, putative | 0.071 | 0.7875 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.0022 | 0.0028 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0072 | 0.0714 | 0.0879 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0241 | 0.0306 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0031 | 0.0253 | 0.0298 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.003 | 0.0241 | 0.0277 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0028 | 0.0222 | 0.0282 |
Loa Loa (eye worm) | cytochrome P450 | 0.001 | 0.0024 | 0.0026 |
Schistosoma mansoni | alpha-glucosidase | 0.0137 | 0.144 | 0.1828 |
Schistosoma mansoni | coup transcription factor | 0.001 | 0.0022 | 0.0028 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.0022 | 0.0004 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0043 | 0.0389 | 0.0427 |
Toxoplasma gondii | eukaryotic initiation factor-4A, putative | 0.071 | 0.7875 | 1 |
Brugia malayi | steroid hormone receptor | 0.001 | 0.0022 | 0.0004 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.001 | 0.0022 | 0.0023 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0035 | 0.0303 | 0.0317 |
Schistosoma mansoni | tar DNA-binding protein | 0.0068 | 0.0673 | 0.0854 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0249 | 0.0316 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0035 | 0.0303 | 0.0384 |
Trypanosoma brucei | glucosidase, putative | 0.0035 | 0.0303 | 0.0355 |
Echinococcus granulosus | cytochrome P450 2K1 | 0.001 | 0.0024 | 0.003 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0653 | 0.0825 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0159 | 0.1688 | 0.1688 |
Brugia malayi | beta-lactamase family protein | 0.0072 | 0.0714 | 0.0885 |
Schistosoma mansoni | tar DNA-binding protein | 0.0068 | 0.0673 | 0.0854 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.001 | 0.0022 | 0.0028 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0253 | 0.0321 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0159 | 0.1688 | 0.2143 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.003 | 0.0241 | 0.0241 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0059 | 0.0572 | 0.0698 |
Echinococcus granulosus | eukaryotic initiation factor 4A | 0.071 | 0.7875 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0253 | 0.0317 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.001 | 0.0022 | 0.0004 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Drug uptake (ADMET) | = 600 nM | Drug level in CD1 mouse brain at 5 mg/kg, ip after 1 hr by LC-MS/MS system | ChEMBL. | 24992153 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.