Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | polyomavirus enhancer activator 3 pea3 | 0.0011 | 0.0041 | 0.0045 |
Schistosoma mansoni | ets-related | 0.0011 | 0.0041 | 0.0045 |
Leishmania major | solanesyl-diphosphate synthase, putative | 0.0411 | 0.2525 | 0.2784 |
Mycobacterium ulcerans | polyprenyl synthetase IdsB | 0.0411 | 0.2525 | 0.2784 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0013 | 0.0052 | 0.0057 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0035 | 0.0038 |
Brugia malayi | conserved hypotetical protein | 0.0005 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0035 | 0.0038 |
Wolbachia endosymbiont of Brugia malayi | geranylgeranyl pyrophosphate synthase | 0.0411 | 0.2525 | 1 |
Brugia malayi | hypothetical protein | 0.0042 | 0.023 | 0.0254 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0005 | 0.0005 | 0.0006 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0005 | 0.0002 | 0.0002 |
Echinococcus multilocularis | protein C ets 2 | 0.0011 | 0.0041 | 0.0041 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0013 | 0.0014 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0042 | 0.0235 | 0.0259 |
Trypanosoma cruzi | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0005 | 0.0004 | 0.0004 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0349 | 0.2138 | 0.2358 |
Trypanosoma cruzi | solanesyl-diphosphate synthase, putative | 0.0411 | 0.2525 | 0.2784 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0022 | 0.0108 | 0.0119 |
Brugia malayi | acetyl-Coenzyme A synthetase 2 | 0.0022 | 0.0108 | 0.0119 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0005 | 0.0002 | 0.0042 |
Schistosoma mansoni | inositol monophosphatase | 0.0042 | 0.0235 | 0.0259 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0007 | 0.0017 | 0.0017 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0318 | 0.035 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0318 | 0.035 |
Entamoeba histolytica | hypothetical protein | 0.0042 | 0.023 | 0.0913 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0005 | 0.0002 | 0.0002 |
Toxoplasma gondii | AMP-binding enzyme domain-containing protein | 0.0022 | 0.0108 | 0.0119 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.001 | 0.0035 | 0.0038 |
Echinococcus multilocularis | cpg binding protein | 0.003 | 0.0161 | 0.0161 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0005 | 0.0002 | 0.0002 |
Brugia malayi | ecdysone receptor | 0.0005 | 0.0002 | 0.0002 |
Trypanosoma cruzi | polyprenyl synthase, putative | 0.0582 | 0.3585 | 0.3952 |
Mycobacterium tuberculosis | Probable geranylgeranyl pyrophosphate synthetase IdsA2 (ggppsase) (GGPP synthetase) (geranylgeranyl diphosphate synthase) | 0.1465 | 0.907 | 1 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0349 | 0.2138 | 0.2358 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0165 | 0.0997 | 0.11 |
Trichomonas vaginalis | DNA helicase recq1, putative | 0.0024 | 0.0122 | 0.0134 |
Echinococcus granulosus | geminin | 0.0196 | 0.1188 | 0.1309 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0005 | 0.0006 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0024 | 0.0122 | 0.0134 |
Entamoeba histolytica | recQ family helicase, putative | 0.0013 | 0.0052 | 0.0206 |
Schistosoma mansoni | nuclear receptor | 0.0005 | 0.0002 | 0.0002 |
Toxoplasma gondii | propionate-CoA ligase | 0.0022 | 0.0108 | 0.0119 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0022 | 0.0108 | 0.0119 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0042 | 0.0235 | 0.0259 |
Brugia malayi | ecdysteroid receptor | 0.001 | 0.0035 | 0.0038 |
Entamoeba histolytica | geranylgeranyl pyrophosphate synthase, putative | 0.0411 | 0.2525 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0052 | 0.0298 | 0.0328 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0074 | 0.0434 | 0.0479 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0005 | 0.0004 | 0.0004 |
Schistosoma mansoni | inositol monophosphatase | 0.0042 | 0.0235 | 0.0259 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0042 | 0.023 | 0.0254 |
Loa Loa (eye worm) | oxidoreductase | 0.0022 | 0.0108 | 0.0119 |
Trichomonas vaginalis | geranylgeranyl pyrophosphate synthase, putative | 0.1465 | 0.907 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0005 | 0.0002 | 0.0002 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0005 | 0.0002 | 0.0002 |
Trypanosoma cruzi | farnesyl pyrophosphate synthase, putative | 0.1465 | 0.907 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0004 | 0.0004 |
Plasmodium vivax | acetyl-CoA synthetase, putative | 0.0022 | 0.0108 | 0.0116 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.001 | 0.0035 | 0.0038 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0005 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | ets-domain-containing protein | 0.0011 | 0.0041 | 0.0045 |
Brugia malayi | AMP-binding enzyme family protein | 0.0074 | 0.0434 | 0.0479 |
Trypanosoma cruzi | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0005 | 0.0004 | 0.0004 |
Echinococcus multilocularis | ETS transcription factor Elf 1 | 0.0011 | 0.0041 | 0.0041 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.001 | 0.0035 | 0.0038 |
Mycobacterium ulcerans | hypothetical protein | 0.0074 | 0.0434 | 0.0479 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.001 | 0.0035 | 0.0038 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0053 | 0.0299 | 0.0329 |
Brugia malayi | AMP-binding enzyme family protein | 0.0022 | 0.0108 | 0.0119 |
Loa Loa (eye worm) | steroid hormone receptor | 0.001 | 0.0035 | 0.0038 |
Schistosoma mansoni | hypothetical protein | 0.0196 | 0.1188 | 0.1309 |
Mycobacterium tuberculosis | Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase | 0.0022 | 0.0108 | 0.0119 |
Echinococcus granulosus | ETS transcription factor Elf 5 | 0.0011 | 0.0041 | 0.0045 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.0035 | 0.0038 |
Entamoeba histolytica | long-chain-fatty-acid--CoA ligase, putative | 0.0022 | 0.0108 | 0.0428 |
Plasmodium falciparum | ADP-dependent DNA helicase RecQ | 0.0021 | 0.0103 | 0.0077 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.0035 | 0.0035 |
Echinococcus granulosus | muscleblind protein | 0.032 | 0.1962 | 0.2164 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.0035 | 0.0038 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.0034 | 0.0037 |
Onchocerca volvulus | 0.0029 | 0.0151 | 0.3472 | |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0042 | 0.0235 | 0.0235 |
Mycobacterium tuberculosis | PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0019 | 0.0089 | 0.0098 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0056 | 0.0318 | 0.035 |
Schistosoma mansoni | ets | 0.0011 | 0.0041 | 0.0045 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0056 | 0.0318 | 0.0347 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.001 | 0.0035 | 0.0038 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0022 | 0.0108 | 0.0119 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0007 | 0.0017 | 0.0018 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.001 | 0.0035 | 0.0038 |
Brugia malayi | transcription factor E74 isoform | 0.0011 | 0.0041 | 0.0045 |
Leishmania major | polyprenyl synthase, putative | 0.0582 | 0.3585 | 0.3952 |
Schistosoma mansoni | hypothetical protein | 0.0042 | 0.023 | 0.0254 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0041 | 0.0045 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0049 | 0.0277 | 0.0305 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0061 | 0.0351 | 0.0387 |
Loa Loa (eye worm) | hypothetical protein | 0.032 | 0.1962 | 0.2164 |
Brugia malayi | AMP-binding enzyme family protein | 0.0022 | 0.0108 | 0.0119 |
Schistosoma mansoni | nuclear hormone receptor | 0.0005 | 0.0002 | 0.0002 |
Brugia malayi | nuclear receptor NHR-88 | 0.001 | 0.0035 | 0.0038 |
Mycobacterium tuberculosis | Probable peptide synthetase Nrp (peptide synthase) | 0.0022 | 0.0108 | 0.0119 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0002 | 0.0002 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.001 | 0.0035 | 0.0038 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0005 | 0.0005 | 0.0006 |
Schistosoma mansoni | DNA helicase recq5 | 0.001 | 0.0034 | 0.0037 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0042 | 0.0235 | 0.0259 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.001 | 0.0035 | 0.0038 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0022 | 0.0108 | 0.0119 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.001 | 0.0035 | 0.0038 |
Mycobacterium ulcerans | bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase | 0.0022 | 0.0108 | 0.0119 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0022 | 0.0108 | 0.0119 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0005 | 0.0005 | 0.0006 |
Loa Loa (eye worm) | RecQ helicase | 0.0024 | 0.0122 | 0.0134 |
Schistosoma mansoni | acetyl-CoA synthetase | 0.0022 | 0.0108 | 0.0119 |
Brugia malayi | AMP-binding enzyme family protein | 0.0074 | 0.0434 | 0.0479 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0013 | 0.0014 |
Onchocerca volvulus | 0.0074 | 0.0434 | 1 | |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0007 | 0.0017 | 0.0018 |
Brugia malayi | Muscleblind-like protein | 0.032 | 0.1962 | 0.2164 |
Mycobacterium tuberculosis | Peptide synthetase MbtF (peptide synthase) | 0.0022 | 0.0108 | 0.0119 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.001 | 0.0035 | 0.0038 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.001 | 0.0035 | 0.0038 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.001 | 0.0035 | 0.0035 |
Brugia malayi | tailless protein | 0.0005 | 0.0002 | 0.0002 |
Brugia malayi | DNA-binding protein D-ETS-3 | 0.0011 | 0.0041 | 0.0045 |
Onchocerca volvulus | 0.0022 | 0.0108 | 0.2488 | |
Brugia malayi | hypothetical protein | 0.0005 | 0.0005 | 0.0006 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0002 | 0.0002 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.001 | 0.0035 | 0.0799 |
Toxoplasma gondii | polyprenyl synthetase superfamily protein | 0.0411 | 0.2525 | 0.2784 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0434 | 0.0479 |
Mycobacterium leprae | POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) | 0.0022 | 0.0108 | 0.0428 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0035 | 0.0038 |
Loa Loa (eye worm) | DNA-binding protein D-ETS-3 | 0.0011 | 0.0041 | 0.0045 |
Echinococcus granulosus | ETS transcription factor Elf 2 | 0.0011 | 0.0041 | 0.0045 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0035 | 0.0038 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0052 | 0.0298 | 0.0328 |
Trypanosoma cruzi | polyprenyl synthase, putative | 0.0582 | 0.3585 | 0.3952 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0013 | 0.0014 |
Loa Loa (eye worm) | polyprenyl synthetase | 0.1465 | 0.907 | 1 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0022 | 0.0108 | 0.0119 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.001 | 0.0035 | 0.0038 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0022 | 0.0108 | 0.0119 |
Leishmania major | long-chain-fatty-acid-CoA ligase, putative | 0.0022 | 0.0108 | 0.0119 |
Echinococcus granulosus | ETS transcription factor Elf 1 | 0.0011 | 0.0041 | 0.0045 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0002 | 0.0002 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0074 | 0.0434 | 0.0479 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0052 | 0.0298 | 0.0328 |
Mycobacterium ulcerans | phenyloxazoline synthase MbtB | 0.0022 | 0.0108 | 0.0119 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0052 | 0.0298 | 0.0328 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0056 | 0.0318 | 0.1257 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0349 | 0.2138 | 0.2358 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0013 | 0.0014 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0009 | 0.0027 | 0.003 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0349 | 0.2138 | 0.2358 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.001 | 0.0035 | 0.0038 |
Wolbachia endosymbiont of Brugia malayi | geranylgeranyl pyrophosphate synthase | 0.0411 | 0.2525 | 1 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0022 | 0.0108 | 0.0119 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0022 | 0.0108 | 0.0119 |
Treponema pallidum | octaprenyl-diphosphate synthase | 0.0582 | 0.3585 | 1 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0074 | 0.0434 | 0.172 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0005 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0108 | 0.0119 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.001 | 0.0035 | 0.0038 |
Schistosoma mansoni | DNA helicase recq1 | 0.001 | 0.0034 | 0.0037 |
Giardia lamblia | Sgs1 DNA helicase, putative | 0.001 | 0.0034 | 0.0037 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0035 | 0.0038 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0042 | 0.0235 | 0.0259 |
Brugia malayi | geranylgeranyl pyrophosphate synthetase | 0.0582 | 0.3585 | 0.3952 |
Echinococcus multilocularis | ATP dependent DNA helicase Q5 | 0.001 | 0.0034 | 0.0034 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0038 | 0.0208 | 0.0229 |
Echinococcus granulosus | decaprenyl diphosphate synthase subunit 1 | 0.0411 | 0.2525 | 0.2784 |
Trypanosoma cruzi | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0013 | 0.0052 | 0.0057 |
Loa Loa (eye worm) | histone methyltransferase | 0.0009 | 0.0028 | 0.003 |
Mycobacterium tuberculosis | Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0022 | 0.0108 | 0.0119 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0042 | 0.0235 | 0.0259 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0022 | 0.0108 | 0.0119 |
Trypanosoma cruzi | solanesyl-diphosphate synthase | 0.0411 | 0.2525 | 0.2784 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0318 | 0.035 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0042 | 0.023 | 0.023 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0005 | 0.0002 | 0.0002 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0022 | 0.0108 | 0.0119 |
Schistosoma mansoni | zinc finger protein | 0.0005 | 0.0002 | 0.0002 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.0035 | 0.0038 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0005 | 0.0002 | 0.0002 |
Schistosoma mansoni | hypothetical protein | 0.0011 | 0.0041 | 0.0045 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0022 | 0.0108 | 0.0119 |
Onchocerca volvulus | 0.0022 | 0.0108 | 0.2488 | |
Mycobacterium ulcerans | O-succinylbenzoic acid--CoA ligase | 0.0022 | 0.0108 | 0.0119 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0161 | 0.0177 |
Onchocerca volvulus | 0.0022 | 0.0108 | 0.2488 | |
Mycobacterium tuberculosis | P-hydroxybenzoyl-AMP ligase FadD22 | 0.0022 | 0.0108 | 0.0119 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0074 | 0.0434 | 0.0479 |
Echinococcus multilocularis | FTZ F1 alpha | 0.001 | 0.0035 | 0.0035 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.001 | 0.0035 | 0.0035 |
Entamoeba histolytica | bifunctional short chain isoprenyl diphosphate synthase, putative | 0.0411 | 0.2525 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.001 | 0.0035 | 0.0038 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0002 | 0.0002 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.006 | 0.0344 | 0.0379 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0074 | 0.0434 | 0.0479 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.001 | 0.0035 | 0.0038 |
Trypanosoma cruzi | solanesyl-diphosphate synthase, putative | 0.0411 | 0.2525 | 0.2784 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.0035 | 0.0038 |
Onchocerca volvulus | Bile acid receptor homolog | 0.001 | 0.0035 | 0.0799 |
Plasmodium falciparum | acetyl-CoA synthetase, putative | 0.0022 | 0.0108 | 0.0082 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0184 | 0.1113 | 0.1227 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0053 | 0.0299 | 0.0329 |
Mycobacterium ulcerans | peptide synthetase Nrp (peptide synthase) | 0.0022 | 0.0108 | 0.0119 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0002 | 0.0002 |
Plasmodium falciparum | geranylgeranyl pyrophosphate synthase, putative | 0.1465 | 0.907 | 1 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0005 | 0.0002 | 0.0002 |
Mycobacterium ulcerans | acetyl-CoA synthetase | 0.0022 | 0.0108 | 0.0119 |
Mycobacterium tuberculosis | Probable polyprenyl-diphosphate synthase GrcC2 (polyprenyl pyrophosphate synthetase) | 0.0411 | 0.2525 | 0.2784 |
Schistosoma mansoni | nuclear receptor | 0.0005 | 0.0002 | 0.0002 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0052 | 0.0298 | 0.0328 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0042 | 0.0235 | 0.0259 |
Echinococcus multilocularis | decaprenyl diphosphate synthase subunit 1 | 0.0411 | 0.2525 | 0.2525 |
Echinococcus multilocularis | muscleblind protein 1 | 0.032 | 0.1962 | 0.1962 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0013 | 0.0014 |
Schistosoma mansoni | ets-related | 0.0231 | 0.1405 | 0.1549 |
Brugia malayi | nuclear receptor NHR-88 | 0.0005 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0029 | 0.0151 | 0.0166 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0002 | 0.0002 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.0151 | 0.0166 |
Schistosoma mansoni | nuclear hormone receptor | 0.0005 | 0.0002 | 0.0002 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0005 | 0.0002 | 0.0002 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0056 | 0.0318 | 0.0314 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0022 | 0.0108 | 0.0119 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.0035 | 0.0038 |
Brugia malayi | nuclear receptor NHR-67 | 0.0005 | 0.0002 | 0.0002 |
Mycobacterium leprae | POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0022 | 0.0108 | 0.0428 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0074 | 0.0434 | 0.0479 |
Entamoeba histolytica | hypothetical protein | 0.0042 | 0.023 | 0.0913 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase MbtF | 0.0022 | 0.0108 | 0.0119 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0434 | 0.0479 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0005 | 0.0006 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0007 | 0.0017 | 0.0018 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.0035 | 0.0038 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0005 | 0.0002 | 0.0002 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0022 | 0.0108 | 0.0119 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0005 | 0.0005 | 0.0006 |
Schistosoma mansoni | nuclear hormone receptor | 0.001 | 0.0035 | 0.0038 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.0013 | 0.0014 |
Trichomonas vaginalis | geranylgeranyl diphosphate synthase, putative | 0.1465 | 0.907 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.0035 | 0.0038 |
Trypanosoma brucei | solanesyl-diphosphate synthase, putative | 0.0411 | 0.2525 | 0.2784 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0056 | 0.0318 | 0.035 |
Plasmodium vivax | octaprenyl pyrophosphate synthase, putative | 0.0411 | 0.2525 | 0.2782 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0002 | 0.0002 |
Giardia lamblia | Farnesyl diphosphate synthase | 0.1465 | 0.907 | 1 |
Echinococcus multilocularis | geranylgeranyl pyrophosphate synthase | 0.0582 | 0.3585 | 0.3585 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0074 | 0.0434 | 0.172 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0013 | 0.0014 |
Echinococcus granulosus | farnesyl pyrophosphate synthase | 0.1465 | 0.907 | 1 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0022 | 0.0108 | 0.0119 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0005 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | D-ets-4 DNA binding domain-containing protein | 0.0076 | 0.0444 | 0.049 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0318 | 0.035 |
Brugia malayi | Fli-1 protein | 0.0231 | 0.1405 | 0.1549 |
Trypanosoma cruzi | farnesyl pyrophosphate synthase | 0.1465 | 0.907 | 1 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0005 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0005 | 0.0006 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0013 | 0.0014 |
Schistosoma mansoni | farnesyl pyrophosphate synthase | 0.1465 | 0.907 | 1 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.001 | 0.0035 | 0.0799 |
Toxoplasma gondii | polyprenyl synthetase superfamily protein | 0.1465 | 0.907 | 1 |
Echinococcus granulosus | ETS domain containing protein Elk 1 | 0.0011 | 0.0041 | 0.0045 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.001 | 0.0035 | 0.0038 |
Leishmania major | acetyl-CoA synthetase, putative | 0.0022 | 0.0108 | 0.0119 |
Echinococcus multilocularis | muscleblind protein | 0.032 | 0.1962 | 0.1962 |
Brugia malayi | Ets-domain containing protein | 0.0011 | 0.0041 | 0.0045 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.0035 | 0.0035 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0022 | 0.0108 | 0.0119 |
Schistosoma mansoni | coup transcription factor | 0.001 | 0.0035 | 0.0038 |
Plasmodium falciparum | octaprenyl pyrophosphate synthase | 0.0411 | 0.2525 | 0.2757 |
Mycobacterium ulcerans | polyprenyl diphosphate synthetase, GrcC1 | 0.0411 | 0.2525 | 0.2784 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0318 | 0.035 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0022 | 0.0108 | 0.0119 |
Mycobacterium tuberculosis | Possible polyprenyl synthetase IdsB (polyprenyl transferase) (polyprenyl diphosphate synthase) | 0.0411 | 0.2525 | 0.2784 |
Schistosoma mansoni | hypothetical protein | 0.0196 | 0.1188 | 0.1309 |
Echinococcus granulosus | GA binding protein alpha chain | 0.0076 | 0.0444 | 0.049 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.0035 | 0.0038 |
Entamoeba histolytica | recQ family DNA helicase | 0.0005 | 0.0004 | 0.0015 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0035 | 0.0038 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.0034 | 0.0037 |
Echinococcus granulosus | ewsr:fli fusion protein type | 0.0011 | 0.0041 | 0.0045 |
Onchocerca volvulus | 0.001 | 0.0035 | 0.0799 | |
Leishmania major | acetyl-CoA synthetase, putative | 0.0022 | 0.0108 | 0.0119 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0005 | 0.0006 |
Mycobacterium ulcerans | hypothetical protein | 0.0184 | 0.1113 | 0.1227 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0042 | 0.0235 | 0.0259 |
Chlamydia trachomatis | geranylgeranyl pyrophosphate synthase | 0.0411 | 0.2525 | 1 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0042 | 0.023 | 0.0254 |
Toxoplasma gondii | Acetyl-coenzyme A synthetase 2, putative | 0.0022 | 0.0108 | 0.0119 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.0022 | 0.0108 | 0.0119 |
Mycobacterium tuberculosis | Peptide synthetase MbtE (peptide synthase) | 0.0022 | 0.0108 | 0.0119 |
Echinococcus multilocularis | farnesyl pyrophosphate synthase | 0.1465 | 0.907 | 0.907 |
Trypanosoma brucei | farnesyl pyrophosphate synthase | 0.1465 | 0.907 | 1 |
Schistosoma mansoni | blooms syndrome DNA helicase | 0.0019 | 0.009 | 0.0099 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.001 | 0.0035 | 0.0038 |
Brugia malayi | Polyprenyl synthetase family protein | 0.1465 | 0.907 | 1 |
Trypanosoma brucei | long-chain-fatty-acid-CoA ligase, putative | 0.0022 | 0.0108 | 0.0119 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0022 | 0.0108 | 0.0119 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.001 | 0.0035 | 0.0038 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0022 | 0.0108 | 0.0119 |
Echinococcus multilocularis | geminin | 0.0196 | 0.1188 | 0.1188 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0074 | 0.0434 | 0.172 |
Echinococcus granulosus | geranylgeranyl pyrophosphate synthase | 0.0582 | 0.3585 | 0.3952 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0005 | 0.0005 | 0.0005 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.0035 | 0.0038 |
Echinococcus granulosus | bloom syndrome protein | 0.0024 | 0.0122 | 0.0134 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0052 | 0.0298 | 0.0298 |
Onchocerca volvulus | 0.0005 | 0.0002 | 0.0042 | |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0013 | 0.0014 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0074 | 0.0434 | 0.0479 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0013 | 0.0014 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0013 | 0.0014 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0165 | 0.0997 | 0.11 |
Plasmodium vivax | ADP-dependent DNA helicase RecQ, putative | 0.0016 | 0.0073 | 0.0078 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0028 | 0.003 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0005 | 0.0002 | 0.0002 |
Leishmania major | farnesyl pyrophosphate synthase | 0.1465 | 0.907 | 1 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.001 | 0.0035 | 0.0035 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0042 | 0.0235 | 0.0259 |
Loa Loa (eye worm) | D-ets-2 protein | 0.0011 | 0.0041 | 0.0045 |
Echinococcus multilocularis | bloom syndrome protein | 0.0024 | 0.0122 | 0.0122 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0005 | 0.0002 | 0.0002 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0005 | 0.0002 | 0.0002 |
Trypanosoma brucei | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0013 | 0.0052 | 0.0057 |
Brugia malayi | AMP-binding enzyme family protein | 0.0074 | 0.0434 | 0.0479 |
Brugia malayi | Ets-domain containing protein | 0.0076 | 0.0444 | 0.049 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0022 | 0.0108 | 0.0119 |
Echinococcus multilocularis | prenyl (decaprenyl) diphosphate synthase | 0.0411 | 0.2525 | 0.2525 |
Schistosoma mansoni | geranylgeranyl pyrophosphate synthase | 0.0582 | 0.3585 | 0.3952 |
Echinococcus granulosus | protein C ets 2 | 0.0011 | 0.0041 | 0.0045 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0028 | 0.0028 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.001 | 0.0035 | 0.0038 |
Brugia malayi | steroid hormone receptor | 0.001 | 0.0035 | 0.0038 |
Brugia malayi | nuclear hormone receptor | 0.001 | 0.0035 | 0.0038 |
Brugia malayi | AMP-binding enzyme family protein | 0.0022 | 0.0108 | 0.0119 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.001 | 0.0035 | 0.0038 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0005 | 0.0002 | 0.0042 |
Trichomonas vaginalis | helicase, putative | 0.0007 | 0.0013 | 0.0014 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0013 | 0.0014 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0005 | 0.0005 | 0.0006 |
Brugia malayi | hypothetical protein | 0.0005 | 0.0002 | 0.0002 |
Entamoeba histolytica | recQ family helicase, putative | 0.0005 | 0.0003 | 0.001 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0108 | 0.0119 |
Brugia malayi | Ets-domain containing protein | 0.0076 | 0.0444 | 0.049 |
Leishmania major | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0013 | 0.0052 | 0.0057 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0074 | 0.0434 | 0.0479 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0002 | 0.0002 |
Entamoeba histolytica | hypothetical protein | 0.0042 | 0.023 | 0.0913 |
Mycobacterium tuberculosis | Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) | 0.0022 | 0.0108 | 0.0119 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0013 | 0.0014 |
Loa Loa (eye worm) | fli-1 protein | 0.0231 | 0.1405 | 0.1549 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0013 | 0.0014 |
Schistosoma mansoni | trans-prenyltransferase | 0.0411 | 0.2525 | 0.2784 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0052 | 0.0298 | 0.0328 |
Loa Loa (eye worm) | geranylgeranyl pyrophosphate synthetase | 0.0582 | 0.3585 | 0.3952 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0042 | 0.0235 | 0.0259 |
Schistosoma mansoni | blooms syndrome DNA helicase | 0.0005 | 0.0004 | 0.0004 |
Echinococcus granulosus | FTZ F1 alpha | 0.001 | 0.0035 | 0.0038 |
Echinococcus granulosus | cpg binding protein | 0.003 | 0.0161 | 0.0177 |
Brugia malayi | Bloom's syndrome protein homolog | 0.0024 | 0.0122 | 0.0134 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0002 | 0.0002 |
Mycobacterium ulcerans | geranylgeranyl pyrophosphate synthase | 0.1465 | 0.907 | 1 |
Echinococcus granulosus | acetyl coenzyme A synthetase cytoplasmic | 0.0022 | 0.0108 | 0.0119 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0053 | 0.0299 | 0.0329 |
Mycobacterium leprae | PROBABLE POLYPRENYL-DIPHOSPHATE SYNTHASE GRCC1 (POLYPRENYL PYROPHOSPHATE SYNTHETASE) | 0.0411 | 0.2525 | 1 |
Onchocerca volvulus | 0.0022 | 0.0108 | 0.2488 | |
Loa Loa (eye worm) | hypothetical protein | 0.032 | 0.1962 | 0.2164 |
Schistosoma mansoni | gabp alpha | 0.0076 | 0.0444 | 0.049 |
Echinococcus granulosus | ETS transcription factor Elf 2 | 0.0011 | 0.0041 | 0.0045 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.0034 | 0.0037 |
Brugia malayi | nuclear receptor RXR | 0.0005 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0035 | 0.0038 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0074 | 0.0434 | 0.0479 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.001 | 0.0035 | 0.0038 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0002 | 0.0002 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0074 | 0.0434 | 0.172 |
Brugia malayi | hypothetical protein | 0.0005 | 0.0002 | 0.0002 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0005 | 0.0002 | 0.0002 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0007 | 0.0017 | 0.0017 |
Echinococcus granulosus | prenyl decaprenyl diphosphate synthase | 0.0411 | 0.2525 | 0.2784 |
Echinococcus multilocularis | ETS domain containing protein Elk 1 | 0.0011 | 0.0041 | 0.0041 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0013 | 0.0014 |
Brugia malayi | CXXC zinc finger family protein | 0.0029 | 0.0151 | 0.0166 |
Loa Loa (eye worm) | hypothetical protein | 0.0121 | 0.0723 | 0.0797 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.001 | 0.0035 | 0.0035 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.001 | 0.0035 | 0.0038 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0165 | 0.0997 | 0.11 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0034 | 0.0037 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0016 | 0.0072 | 0.0079 |
Entamoeba histolytica | hypothetical protein | 0.0042 | 0.023 | 0.0913 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.0035 | 0.0035 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0052 | 0.0298 | 0.0298 |
Onchocerca volvulus | 0.0005 | 0.0002 | 0.0042 | |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0005 | 0.0002 | 0.0002 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.0035 | 0.0038 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.0035 | 0.0038 |
Echinococcus granulosus | ATP dependent DNA helicase Q5 | 0.001 | 0.0034 | 0.0037 |
Brugia malayi | Polyprenyl synthetase family protein | 0.0411 | 0.2525 | 0.2784 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0005 | 0.0002 | 0.0002 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.001 | 0.0035 | 0.0038 |
Toxoplasma gondii | hypothetical protein | 0.0056 | 0.0322 | 0.0355 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0054 | 0.031 | 0.0342 |
Brugia malayi | Inositol-1 | 0.0042 | 0.0235 | 0.0259 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0013 | 0.0014 |
Brugia malayi | nuclear hormone receptor | 0.0005 | 0.0002 | 0.0002 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.0035 | 0.0038 |
Loa Loa (eye worm) | DR-78 | 0.0005 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.001 | 0.0035 | 0.0038 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.001 | 0.0035 | 0.0038 |
Entamoeba histolytica | geranylgeranyl pyrophosphate synthetase, putative | 0.0411 | 0.2525 | 1 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.001 | 0.0035 | 0.0038 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0049 | 0.0277 | 0.0305 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0005 | 0.0006 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0035 | 0.0038 |
Mycobacterium ulcerans | long-chain-acyl-CoA synthetase | 0.0022 | 0.0108 | 0.0119 |
Trichomonas vaginalis | geranylgeranyl pyrophosphate synthase, putative | 0.1465 | 0.907 | 1 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0053 | 0.0299 | 0.0329 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0005 | 0.0005 | 0.0006 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0038 | 0.0208 | 0.0822 |
Loa Loa (eye worm) | polyprenyl synthetase | 0.0411 | 0.2525 | 0.2784 |
Schistosoma mansoni | hypothetical protein | 0.0011 | 0.0041 | 0.0045 |
Echinococcus multilocularis | ETS transcription factor Elf 2 | 0.0011 | 0.0041 | 0.0041 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0022 | 0.0108 | 0.0119 |
Brugia malayi | hypothetical protein | 0.0005 | 0.0005 | 0.0006 |
Echinococcus multilocularis | ewsr:fli fusion protein type | 0.0011 | 0.0041 | 0.0041 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0002 | 0.0002 |
Schistosoma mansoni | glutathione synthetase | 0.0411 | 0.2525 | 0.2784 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0002 | 0.0002 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.0035 | 0.0035 |
Trypanosoma brucei | acetyl-CoA synthetase, putative | 0.0022 | 0.0108 | 0.0119 |
Loa Loa (eye worm) | inositol-1 | 0.0042 | 0.0235 | 0.0259 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0005 | 0.0002 | 0.0002 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0005 | 0.0002 | 0.0002 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0074 | 0.0434 | 0.0479 |
Mycobacterium leprae | Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) | 0.0022 | 0.0108 | 0.0428 |
Mycobacterium tuberculosis | Probable multifunctional geranylgeranyl pyrophosphate synthetase IdsA1 (GGPP synthetase) (ggppsase) (geranylgeranyl diphosphate | 0.0411 | 0.2525 | 0.2784 |
Loa Loa (eye worm) | D-ets-4 DNA binding domain-containing protein | 0.0011 | 0.0041 | 0.0045 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0049 | 0.0277 | 0.0305 |
Brugia malayi | AMP-binding enzyme family protein | 0.0022 | 0.0108 | 0.0119 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0161 | 0.0177 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0074 | 0.0434 | 0.172 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0052 | 0.0298 | 0.0328 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.0013 | 0.0014 |
Echinococcus multilocularis | ETS transcription factor Elf 5 | 0.0011 | 0.0041 | 0.0041 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0049 | 0.0277 | 0.0305 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.0034 | 0.0037 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0002 | 0.0002 |
Echinococcus multilocularis | acetyl coenzyme A synthetase, cytoplasmic | 0.0022 | 0.0108 | 0.0108 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.001 | 0.0035 | 0.0038 |
Echinococcus multilocularis | GA binding protein alpha chain | 0.0076 | 0.0444 | 0.0444 |
Brugia malayi | nuclear receptor RXR | 0.0005 | 0.0005 | 0.0006 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0041 | 0.0045 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.001 | 0.0035 | 0.0038 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase MbtE | 0.0022 | 0.0108 | 0.0119 |
Echinococcus multilocularis | ets variant gene 4 | 0.0011 | 0.0041 | 0.0041 |
Mycobacterium ulcerans | geranylgeranyl pyrophosphate synthase | 0.1465 | 0.907 | 1 |
Echinococcus granulosus | ATP dependent DNA helicase Q1 | 0.001 | 0.0034 | 0.0037 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0005 | 0.0002 | 0.0002 |
Echinococcus multilocularis | ETS transcription factor Elf 2 | 0.0011 | 0.0041 | 0.0041 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0005 | 0.0002 | 0.0002 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0042 | 0.0235 | 0.0259 |
Plasmodium vivax | geranylgeranyl pyrophosphate synthase | 0.1465 | 0.907 | 1 |
Loa Loa (eye worm) | ATP-dependent DNA helicase | 0.001 | 0.0034 | 0.0037 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0434 | 0.0479 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.001 | 0.0035 | 0.0038 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0074 | 0.0434 | 0.0479 |
Echinococcus multilocularis | ATP dependent DNA helicase Q1 | 0.001 | 0.0034 | 0.0034 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0074 | 0.0434 | 0.0479 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0074 | 0.0434 | 0.0479 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0376 | 0.0414 |
Schistosoma mansoni | elf1 | 0.0011 | 0.0041 | 0.0045 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0042 | 0.0235 | 0.0931 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
ID50 (functional) | ~ 0.001 M | In vitro inhibition of growth of L1210 mouse leukemic cells | ChEMBL. | 7328577 |
ILS (functional) | = 1 % | Increase in life span of tumor L1210 leukemic mice 1-5 days after 200 mg/kg of the compound administered | ChEMBL. | 7328577 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.