Detailed information for compound 1353334

Basic information

Technical information
  • TDR Targets ID: 1353334
  • Name: 2-methyl-N-[2-[(2-methylcyclohexyl)carbamoyl] phenyl]-5,6-dihydro-1,4-oxathiine-3-carboxami de
  • MW: 374.497 | Formula: C20H26N2O3S
  • H donors: 2 H acceptors: 2 LogP: 4.25 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC1CCCCC1NC(=O)c1ccccc1NC(=O)C1=C(C)OCCS1
  • InChi: 1S/C20H26N2O3S/c1-13-7-3-5-9-16(13)21-19(23)15-8-4-6-10-17(15)22-20(24)18-14(2)25-11-12-26-18/h4,6,8,10,13,16H,3,5,7,9,11-12H2,1-2H3,(H,21,23)(H,22,24)
  • InChiKey: JENLIBKCQPUVSS-UHFFFAOYSA-N  

Network

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Synonyms

  • 2-methyl-N-[2-[[(2-methylcyclohexyl)amino]-oxomethyl]phenyl]-5,6-dihydro-1,4-oxathiine-3-carboxamide

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens lysine (K)-specific methyltransferase 2A Starlite/ChEMBL No references
Homo sapiens GNAS complex locus Starlite/ChEMBL No references
Homo sapiens TAR DNA binding protein Starlite/ChEMBL No references
Homo sapiens geminin, DNA replication inhibitor Starlite/ChEMBL No references
Homo sapiens glycoprotein hormones, alpha polypeptide Starlite/ChEMBL No references
Homo sapiens APEX nuclease (multifunctional DNA repair enzyme) 1 Starlite/ChEMBL No references
Homo sapiens glucagon-like peptide 1 receptor Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain Get druggable targets OG5_131088 All targets in OG5_131088
Loa Loa (eye worm) exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania major apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum ko:K10772 AP endonuclease 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma japonicum ko:K04632 guanine nucleotide binding protein (G protein), alpha stimulating, putative Get druggable targets OG5_131088 All targets in OG5_131088
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium berghei AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni mixed-lineage leukemia protein mll Get druggable targets OG5_130642 All targets in OG5_130642
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Giardia lamblia Endonuclease/Exonuclease/phosphatase Get druggable targets OG5_126768 All targets in OG5_126768
Neospora caninum Multidomain chromatinic protein with the following architecture: 3x PHD-bromo-3xPHD-SET domain and associated cysteine cluster a Get druggable targets OG5_130642 All targets in OG5_130642
Leishmania braziliensis apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Theileria parva hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) RNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Cryptosporidium parvum conserved hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) TAR-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Toxoplasma gondii histone lysine methyltransferase SET1 Get druggable targets OG5_130642 All targets in OG5_130642
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus granulosus tar DNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Leishmania infantum apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase Get druggable targets OG5_126768 All targets in OG5_126768
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Neospora caninum hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Brugia malayi RNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma japonicum ko:K09188 myeloid/lymphoid or mixed-lineage leukemia protein 3, putative Get druggable targets OG5_130642 All targets in OG5_130642
Plasmodium knowlesi AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania donovani apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum TAR DNA-binding protein 43, putative Get druggable targets OG5_132461 All targets in OG5_132461
Trypanosoma congolense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Brugia malayi exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma brucei gambiense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Cryptosporidium hominis dna-(apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Brugia malayi TAR-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Leishmania mexicana apurinic/apyrimidinic endonuclease-redox protein,AP-endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus multilocularis tar DNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Schistosoma japonicum TAR DNA-binding protein 43, putative Get druggable targets OG5_132461 All targets in OG5_132461
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Toxoplasma gondii exonuclease III APE Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein Get druggable targets OG5_132461 All targets in OG5_132461
Entamoeba histolytica exodeoxyribonuclease III, putative Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Wolbachia endosymbiont of Brugia malayi exonuclease III Get druggable targets OG5_126768 All targets in OG5_126768
Brugia malayi RNA recognition motif domain containing protein Get druggable targets OG5_132461 All targets in OG5_132461
Trypanosoma cruzi apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Treponema pallidum exodeoxyribonuclease (exoA) Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium yoelii putative AP endonuclease-related Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum ko:K10771 AP endonuclease 1, putative Get druggable targets OG5_126768 All targets in OG5_126768

By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi Hypothetical 65.5 kDa Trp-Asp repeats containing protein F02E8.5 inchromosome X geminin, DNA replication inhibitor 209 aa 176 aa 27.8 %
Toxoplasma gondii intraflagellar transport protein 172, putative glycoprotein hormones, alpha polypeptide 116 aa 94 aa 26.6 %
Schistosoma mansoni GTP-binding protein alpha subunit gna GNAS complex locus 394 aa 450 aa 28.7 %
Loa Loa (eye worm) pigment dispersing factor receptor c glucagon-like peptide 1 receptor 463 aa 388 aa 25.8 %

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0101 0.297 0.297
Leishmania major ATP-binding cassette protein subfamily C, member 6, putative 0.0113 0.3358 0.3358
Giardia lamblia ABC transporter, putative 0.0113 0.3358 1
Schistosoma mansoni voltage-gated potassium channel 0.0029 0.0588 0.0588
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0119 0.3544 0.3278
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0113 0.3358 1
Mycobacterium tuberculosis Probable drugs-transport transmembrane ATP-binding protein ABC transporter 0.0101 0.297 0.297
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0316 1 1
Brugia malayi ABC transporter transmembrane region family protein 0.0113 0.3358 0.3358
Trypanosoma brucei ABC transporter of the mitochondrion, putative 0.0101 0.297 0.8846
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0098 0.2855 0.2855
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0011 0.0004 0.0004
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0101 0.297 0.297
Brugia malayi Cyclic-nucleotide gated cation channel 0.0021 0.0346 0.0346
Echinococcus granulosus multidrug resistance associated protein 4 0.0012 0.004 0.004
Brugia malayi multidrug Resistance Protein family member (mrp-5), putative 0.0101 0.297 0.297
Schistosoma mansoni voltage-gated potassium channel 0.0029 0.0588 0.0588
Schistosoma mansoni ATP-binding cassette sub-family B member 6 mitochondrial precursor (abc6) 0.0098 0.2855 0.2855
Echinococcus granulosus multidrug resistance associated protein 1 0.0113 0.3358 0.3358
Schistosoma mansoni ap endonuclease 0.0023 0.0396 0.0396
Echinococcus multilocularis sodium channel protein 0.0087 0.2501 0.2501
Loa Loa (eye worm) ABC transporter transmembrane region family protein 0.0113 0.3358 0.3358
Loa Loa (eye worm) latrophilin receptor protein 2 0.0019 0.0276 0.0276
Brugia malayi ABC transporter transmembrane region family protein 0.0098 0.2855 0.2855
Leishmania major p-glycoprotein 0.0316 1 1
Echinococcus multilocularis ATP binding cassette sub family B 0.0101 0.297 0.297
Brugia malayi RNA binding protein 0.0076 0.2156 0.2156
Entamoeba histolytica P-glycoprotein-2, putative 0.0098 0.2855 0.256
Loa Loa (eye worm) hypothetical protein 0.0021 0.0346 0.0346
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0055 0.146 0.146
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0316 1 1
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0021 0.0346 0.0346
Echinococcus multilocularis expressed conserved protein 0.0112 0.3308 0.3308
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0023 0.0396 0.1179
Entamoeba histolytica P-glycoprotein-2 0.0316 1 1
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0021 0.0346 0.0346
Loa Loa (eye worm) hypothetical protein 0.0051 0.1322 0.1322
Entamoeba histolytica P-glycoprotein-1 0.0316 1 1
Echinococcus multilocularis ATP binding cassette sub family B 0.0313 0.9884 0.9884
Giardia lamblia MRP-like ABC transporter 0.0113 0.3358 1
Giardia lamblia Multidrug resistance-associated protein 1 0.0113 0.3358 1
Trichomonas vaginalis conserved hypothetical protein 0.0098 0.2855 0.2855
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0023 0.0396 0.0396
Schistosoma mansoni multidrug resistance protein 0.0098 0.2855 0.2855
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0316 1 1
Schistosoma mansoni ATP-binding cassette sub-family B member 7 mitochondrial precursor (abc7) 0.0101 0.297 0.297
Plasmodium falciparum multidrug resistance-associated protein 2 0.0101 0.297 0.297
Schistosoma mansoni multidrug resistance protein 0.0316 1 1
Plasmodium vivax ABC transporter B family member 6, putative 0.0101 0.297 0.297
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0316 1 1
Loa Loa (eye worm) RNA binding protein 0.0076 0.2156 0.2156
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0021 0.0346 0.0346
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0021 0.0346 0.0346
Echinococcus multilocularis multidrug resistance associated protein 4 0.0012 0.004 0.004
Brugia malayi TAR-binding protein 0.0076 0.2156 0.2156
Trichomonas vaginalis ABC transporter, putative 0.0316 1 1
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.024 0.024
Plasmodium vivax ABC transporter B family member 3, putative 0.0101 0.297 0.297
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0086 0.2456 0.2456
Leishmania major ATP-binding cassette protein subfamily C, member 8, putative 0.0101 0.297 0.297
Plasmodium falciparum ABC transporter B family member 7, putative 0.0101 0.297 0.297
Mycobacterium tuberculosis Probable glutamine-transport ATP-binding protein ABC transporter GlnQ 0.0014 0.0116 0.0116
Loa Loa (eye worm) hypothetical protein 0.0184 0.5678 0.5678
Loa Loa (eye worm) multidrug resistance protein 3 0.0316 1 1
Loa Loa (eye worm) CXXC zinc finger family protein 0.0035 0.0788 0.0788
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0086 0.2456 0.2456
Brugia malayi RNA recognition motif domain containing protein 0.0076 0.2156 0.2156
Schistosoma mansoni 60S ribosomal protein L21 0.0018 0.024 0.024
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0021 0.0346 0.0346
Schistosoma mansoni tar DNA-binding protein 0.0076 0.2156 0.2156
Leishmania major pentamidine resistance protein 1 0.0113 0.3358 0.3358
Leishmania major ATP-binding cassette protein subfamily C, member 1, putative 0.0113 0.3358 0.3358
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0019 0.0276 0.0276
Plasmodium vivax ABC transporter B family member 5, putative 0.0101 0.297 0.297
Leishmania major ATP-binding cassette protein subfamily C, member 2, putative 0.0113 0.3358 0.3358
Loa Loa (eye worm) hypothetical protein 0.0041 0.0999 0.0999
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0316 1 1
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0316 1 1
Schistosoma mansoni multidrug resistance protein 0.0316 1 1
Trichomonas vaginalis ABC transporter, putative 0.0316 1 1
Echinococcus multilocularis ATP binding cassette sub family B 0.0101 0.297 0.297
Echinococcus multilocularis cpg binding protein 0.0037 0.0852 0.0852
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0121 0.3604 0.3604
Echinococcus granulosus multidrug resistance protein 1 0.0218 0.6798 0.6798
Schistosoma mansoni tar DNA-binding protein 0.0076 0.2156 0.2156
Loa Loa (eye worm) hypothetical protein 0.0098 0.2855 0.2855
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0316 1 1
Schistosoma mansoni cpg binding protein 0.0037 0.0852 0.0852
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0316 1 1
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0316 1 1
Plasmodium vivax ABC transporter B family member 7, putative 0.0101 0.297 0.297
Schistosoma mansoni cpg binding protein 0.0035 0.0788 0.0788
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0086 0.2456 0.2456
Echinococcus multilocularis geminin 0.0205 0.635 0.635
Plasmodium vivax ABC transporter B family member 4, putative 0.0101 0.297 0.297
Echinococcus granulosus multidrug resistance protein 1 0.0316 1 1
Schistosoma mansoni multidrug resistance protein 0.0113 0.3358 0.3358
Schistosoma mansoni hypothetical protein 0.0049 0.1262 0.1262
Echinococcus multilocularis hyperpolarization activated cyclic 0.0021 0.0346 0.0346
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0316 1 1
Trichomonas vaginalis ABC transporter, putative 0.0316 1 1
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0019 0.0276 0.0276
Brugia malayi ABC transporter family protein 0.0316 1 1
Entamoeba histolytica ATP-binding cassette protein, putative 0.0113 0.3358 0.3084
Brugia malayi ABC transporter family protein 0.0101 0.297 0.297
Schistosoma mansoni smdr1 0.0101 0.297 0.297
Loa Loa (eye worm) TAR-binding protein 0.0076 0.2156 0.2156
Trichomonas vaginalis ap endonuclease, putative 0.0023 0.0396 0.0396
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0316 1 1
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0316 1 1
Entamoeba histolytica P-glycoprotein-5 0.0316 1 1
Mycobacterium leprae PROBABLE DRUGS-TRANSPORT TRANSMEMBRANE ATP-BINDING PROTEIN ABC TRANSPORTER 0.0101 0.297 1
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0076 0.2156 0.2156
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.1322 0.1322
Plasmodium falciparum ABC transporter B family member 3, putative 0.0101 0.297 0.297
Loa Loa (eye worm) hypothetical protein 0.011 0.3242 0.3242
Brugia malayi ABC transporter family protein 0.0101 0.297 0.297
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0113 0.3358 1
Trichomonas vaginalis abcb9, putative 0.0316 1 1
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0313 0.9884 0.9884
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0316 1 1
Echinococcus granulosus hyperpolarization activated cyclic 0.0021 0.0346 0.0346
Giardia lamblia Hypothetical protein 0.0098 0.2855 0.8502
Echinococcus multilocularis ATP binding cassette sub family B 0.0101 0.297 0.297
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0316 1 1
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0055 0.146 0.146
Echinococcus multilocularis sterol regulatory element binding protein 0.0051 0.1322 0.1322
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0021 0.0346 0.0346
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0316 1 1
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0113 0.3358 1
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0019 0.0276 0.0276
Loa Loa (eye worm) hypothetical protein 0.0316 1 1
Schistosoma mansoni multidrug resistance protein 0.0316 1 1
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0029 0.0588 0.0588
Plasmodium falciparum ABC transporter B family member 5, putative 0.0101 0.297 0.297
Echinococcus multilocularis Niemann Pick C1 protein 0.017 0.5214 0.5214
Loa Loa (eye worm) hypothetical protein 0.0062 0.1698 0.1698
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0023 0.0396 0.0396
Echinococcus granulosus sterol regulatory element binding protein 0.0051 0.1322 0.1322
Giardia lamblia Multidrug resistance-associated protein 1 0.0113 0.3358 1
Toxoplasma gondii ATP-binding cassette sub-family B member 5 0.0101 0.297 0.297
Loa Loa (eye worm) ABC transporter 0.0101 0.297 0.297
Onchocerca volvulus 0.0035 0.0788 0.0788
Schistosoma mansoni hypothetical protein 0.0019 0.0276 0.0276
Loa Loa (eye worm) hypothetical protein 0.0316 1 1
Schistosoma mansoni hypothetical protein 0.0019 0.0276 0.0276
Echinococcus granulosus Niemann Pick C1 protein 0.0119 0.3544 0.3544
Echinococcus granulosus Niemann Pick C1 protein 0.017 0.5214 0.5214
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0218 0.6798 0.6798
Echinococcus granulosus multidrug resistance protein 1 0.0218 0.6798 0.6798
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0316 1 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.146 0.146
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0316 1 1
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0021 0.0346 0.0346
Echinococcus granulosus ATP binding cassette sub family B 0.0101 0.297 0.297
Echinococcus multilocularis Niemann Pick C1 protein 0.0119 0.3544 0.3544
Entamoeba histolytica P-glycoprotein-2, putative 0.0316 1 1
Echinococcus multilocularis multidrug resistance associated protein 1 0.0113 0.3358 0.3358
Plasmodium falciparum multidrug resistance protein 2 0.0101 0.297 0.297
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0021 0.0346 0.0346
Loa Loa (eye worm) hypothetical protein 0.0113 0.3358 0.3358
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0101 0.297 0.297
Schistosoma mansoni multidrug resistance protein 0.0113 0.3358 0.3358
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.146 0.146
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0021 0.0346 0.0346
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0021 0.0346 0.0346
Trichomonas vaginalis abcb9, putative 0.0316 1 1
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0023 0.0396 0.1333
Trichomonas vaginalis ap endonuclease, putative 0.0023 0.0396 0.0396
Loa Loa (eye worm) hypothetical protein 0.0019 0.0276 0.0276
Schistosoma mansoni hypothetical protein 0.0019 0.0276 0.0276
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0075 0.211 0.211
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0021 0.0346 0.0346
Trypanosoma cruzi ABC transporter of the mitochondrion, putative 0.0101 0.297 0.8846
Loa Loa (eye worm) inward rectifying k channel family protein 1 0.0184 0.5678 0.5678
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0316 1 1
Schistosoma mansoni tar DNA-binding protein 0.0076 0.2156 0.2156
Trichomonas vaginalis abcb9, putative 0.0316 1 1
Echinococcus granulosus geminin 0.0205 0.635 0.635
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0316 1 1
Echinococcus multilocularis hyperpolarization activated cyclic 0.0021 0.0346 0.0346
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0316 1 1
Schistosoma mansoni cpg binding protein 0.0037 0.0852 0.0852
Echinococcus granulosus ATP binding cassette sub family B 0.0098 0.2855 0.2855
Loa Loa (eye worm) hypothetical protein 0.006 0.1623 0.1623
Plasmodium vivax multidrug resistance protein 1, putative 0.0316 1 1
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0098 0.2855 0.2855
Loa Loa (eye worm) hypothetical protein 0.0101 0.297 0.297
Echinococcus granulosus GPCR family 2 0.0019 0.0276 0.0276
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0316 1 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.006 0.1623 0.1623
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0023 0.0396 0.1179
Schistosoma mansoni hypothetical protein 0.0049 0.1262 0.1262
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0075 0.211 0.211
Treponema pallidum exodeoxyribonuclease (exoA) 0.0023 0.0396 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0074 0.206 0.206
Echinococcus granulosus multidrug resistance associated protein 7 0.0113 0.3358 0.3358
Echinococcus multilocularis ATP binding cassette sub family B 0.0101 0.297 0.297
Loa Loa (eye worm) ABC transporter 0.0101 0.297 0.297
Entamoeba histolytica P-glyco protein 6, putative 0.0316 1 1
Entamoeba histolytica P-glycoprotein 6, putative 0.0101 0.297 0.2681
Loa Loa (eye worm) hypothetical protein 0.0184 0.5678 0.5678
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0021 0.0346 0.0346
Echinococcus granulosus multidrug resistance protein 1 0.0316 1 1
Schistosoma mansoni tar DNA-binding protein 0.0076 0.2156 0.2156
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0023 0.0396 0.0396
Echinococcus granulosus ATP binding cassette sub family B 0.0101 0.297 0.297
Plasmodium falciparum multidrug resistance-associated protein 1 0.0101 0.297 0.297
Entamoeba histolytica ABC transporter, putative 0.0113 0.3358 0.3084
Mycobacterium leprae PROBABLE DRUGS-TRANSPORT TRANSMEMBRANE ATP-BINDING PROTEIN ABC TRANSPORTER 0.0101 0.297 1
Echinococcus multilocularis multidrug resistance protein 1 0.0316 1 1
Echinococcus multilocularis multidrug resistance associated protein 7 0.0113 0.3358 0.3358
Echinococcus multilocularis tar DNA binding protein 0.0076 0.2156 0.2156
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0087 0.2501 0.2501
Schistosoma mansoni hypothetical protein 0.0205 0.635 0.635
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0316 1 1
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0051 0.1322 0.1322
Loa Loa (eye worm) pigment dispersing factor receptor c 0.006 0.1623 0.1623
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0316 1 1
Trichomonas vaginalis ABC transporter, putative 0.0316 1 1
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0021 0.0346 0.0346
Schistosoma mansoni voltage-gated potassium channel 0.0021 0.0346 0.0346
Echinococcus granulosus cpg binding protein 0.0037 0.0852 0.0852
Leishmania major ABC-thiol transporter 0.0113 0.3358 0.3358
Brugia malayi CHE-14 protein 0.0051 0.1322 0.1322
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0021 0.0346 0.0346
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0019 0.0276 0.0276
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0316 1 1
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0316 1 1
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0023 0.0396 0.0396
Entamoeba histolytica ATP-binding cassette protein, putative 0.0113 0.3358 0.3084
Wolbachia endosymbiont of Brugia malayi ABC-type protease secretion system, ATPase and permease component, AprD 0.0101 0.297 1
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0113 0.3358 0.3358
Brugia malayi Niemann-Pick C1 protein precursor 0.0119 0.3544 0.3544
Echinococcus granulosus hyperpolarization activated cyclic 0.0021 0.0346 0.0346
Loa Loa (eye worm) hypothetical protein 0.0119 0.3544 0.3544
Loa Loa (eye worm) hypothetical protein 0.0184 0.5678 0.5678
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0023 0.0396 0.1179
Toxoplasma gondii ABC transporter family protein 0.0101 0.297 0.297
Brugia malayi hypothetical protein 0.0101 0.297 0.297
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0316 1 1
Loa Loa (eye worm) hypothetical protein 0.0029 0.0588 0.0588
Plasmodium falciparum ABC transporter B family member 6, putative 0.0101 0.297 0.297
Loa Loa (eye worm) multidrug resistance-associated protein 0.0015 0.0156 0.0156
Leishmania major p-glycoprotein e 0.0113 0.3358 0.3358
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0316 1 1
Echinococcus granulosus multidrug resistance protein 1 0.0316 1 1
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0113 0.3358 1
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0316 1 1
Trypanosoma cruzi multidrug resistance protein E, putative 0.0113 0.3358 1
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0101 0.297 1
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.006 0.1623 0.1623
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0316 1 1
Schistosoma mansoni voltage-gated potassium channel 0.0093 0.2698 0.2698
Entamoeba histolytica P-glycoprotein 5, putative 0.0098 0.2855 0.256
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0101 0.297 0.297
Plasmodium falciparum multidrug resistance protein 1 0.0316 1 1
Schistosoma mansoni ap endonuclease 0.0023 0.0396 0.0396
Trypanosoma brucei p-glycoprotein 0.0113 0.3358 1
Wolbachia endosymbiont of Brugia malayi ABC-type multidrug transport system, ATPase and permease component 0.0101 0.297 1
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0029 0.0588 0.0588
Brugia malayi multidrug resistance related protein 1 0.0113 0.3358 0.3358
Brugia malayi Latrophilin receptor protein 2 0.0019 0.0276 0.0276
Mycobacterium ulcerans drugs-transport transmembrane ATP-binding protein ABC transporter 0.0101 0.297 1
Brugia malayi ABC transporter 0.0101 0.297 0.297
Schistosoma mansoni hypothetical protein 0.0049 0.1262 0.1262
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0316 1 1
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0101 0.297 0.297
Echinococcus multilocularis protein patched 0.0051 0.1322 0.1322
Echinococcus granulosus tar DNA binding protein 0.0076 0.2156 0.2156
Echinococcus multilocularis multidrug resistance protein 1 0.0218 0.6798 0.6798
Giardia lamblia Multidrug resistance-associated protein Mrp2 0.0098 0.2855 0.8502
Brugia malayi ABC transporter family protein 0.0101 0.297 0.297
Entamoeba histolytica ATP-binding cassette protein, putative 0.0113 0.3358 0.3084
Brugia malayi ABC transporter transmembrane region family protein 0.0101 0.297 0.297
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.146 0.146
Schistosoma mansoni hypothetical protein 0.0049 0.1262 0.1262
Echinococcus granulosus expressed conserved protein 0.0112 0.3308 0.3308
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0021 0.0346 0.0346
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0101 0.297 1
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0023 0.0396 0.0396
Trypanosoma brucei multidrug resistance protein E 0.0113 0.3358 1
Plasmodium vivax multidrug resistance-associated protein 1, putative 0.0101 0.297 0.297
Schistosoma mansoni hypothetical protein 0.0019 0.0276 0.0276
Entamoeba histolytica P-glycoprotein 6, putative 0.0101 0.297 0.2681
Schistosoma mansoni multidrug resistance protein 0.0113 0.3358 0.3358
Loa Loa (eye worm) hypothetical protein 0.0113 0.3358 0.3358
Toxoplasma gondii ABC transporter, putative 0.0101 0.297 0.297
Brugia malayi latrophilin 2 splice variant baaae 0.0041 0.0999 0.0999
Schistosoma mansoni hypothetical protein 0.0041 0.0999 0.0999
Entamoeba histolytica P-glycoprotein 5, putative 0.0316 1 1
Leishmania major ATP-binding cassette protein subfamily C, member 5, putative 0.0113 0.3358 0.3358
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0023 0.0396 0.0396
Schistosoma mansoni tar DNA-binding protein 0.0076 0.2156 0.2156
Trypanosoma cruzi ABC transporter, mitochondrial, putative 0.0101 0.297 0.8846
Schistosoma mansoni voltage-gated potassium channel 0.0093 0.2698 0.2698
Toxoplasma gondii histone lysine methyltransferase SET1 0.0066 0.1803 0.1803
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0029 0.0588 0.0588
Brugia malayi CXXC zinc finger family protein 0.0035 0.0788 0.0788
Brugia malayi ABC transporter 0.0098 0.2855 0.2855
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0316 1 1
Loa Loa (eye worm) hypothetical protein 0.0075 0.2109 0.2109
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0021 0.0346 0.0346
Entamoeba histolytica multidrug resistance protein, putative 0.0113 0.3358 0.3084
Mycobacterium ulcerans component linked with the assembly of cytochrome transport transmembrane ATP-binding protein ABC transporter CydD 0.0101 0.297 1
Toxoplasma gondii hypothetical protein 0.0184 0.5678 0.5678
Echinococcus granulosus Protein patched homolog 1 0.0051 0.1322 0.1322
Loa Loa (eye worm) hypothetical protein 0.0313 0.9884 0.9884
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0023 0.0396 0.0396
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0316 1 1
Trichomonas vaginalis taga, putative 0.0316 1 1
Echinococcus multilocularis protein dispatched 1 0.0058 0.1558 0.1558
Echinococcus multilocularis voltage gated potassium channel 0.0029 0.0588 0.0588
Schistosoma mansoni multidrug resistance protein 0.0101 0.297 0.297
Schistosoma mansoni patched 1 0.0051 0.1322 0.1322
Brugia malayi exodeoxyribonuclease III family protein 0.0023 0.0396 0.0396
Schistosoma mansoni hypothetical protein 0.0205 0.635 0.635
Leishmania major ATP-binding cassette protein subfamily B, member 1, putative 0.0101 0.297 0.297
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0101 0.297 1
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0023 0.0396 0.1179
Plasmodium falciparum ABC transporter B family member 4, putative 0.0101 0.297 0.297
Loa Loa (eye worm) histone methyltransferase 0.0011 0.0004 0.0004
Plasmodium vivax multidrug resistance protein 2, putative 0.0101 0.297 0.297
Entamoeba histolytica hypothetical protein 0.0113 0.3358 0.3084
Onchocerca volvulus 0.0316 1 1
Echinococcus granulosus sodium channel protein 0.0087 0.2501 0.2501
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0316 1 1
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0316 1 1
Giardia lamblia Multidrug resistance-associated protein 1 0.011 0.3242 0.9656
Brugia malayi P-glycoprotein-like protein 0.0101 0.297 0.297
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.146 0.146
Echinococcus multilocularis GPCR, family 2 0.0019 0.0276 0.0276
Entamoeba histolytica P-glycoprotein-2 0.0316 1 1
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0011 0.0004 0.0004
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0101 0.297 0.297
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0316 1 1
Schistosoma mansoni multidrug resistance protein 0.0113 0.3358 0.3358
Echinococcus multilocularis multidrug resistance protein 1 0.0316 1 1
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0086 0.2456 0.2456
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0316 1 1
Loa Loa (eye worm) ABC transporter 0.0101 0.297 0.297
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0087 0.2501 0.2501
Schistosoma mansoni smdr2 0.0316 1 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.146 0.146
Entamoeba histolytica ATP-binding cassette protein, putative 0.0113 0.3358 0.3084
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.146 0.146
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.146 0.146
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0316 1 1
Leishmania major ATP-binding cassette protein subfamily B, member 3, putative 0.0101 0.297 0.297
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0019 0.0276 0.0276
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0098 0.2855 0.2855
Plasmodium vivax multidrug resistance-associated protein 2, putative 0.0101 0.297 0.297
Trypanosoma cruzi hypothetical protein 0.0012 0.004 0.0119
Mycobacterium tuberculosis Iron-regulated transporter IrtA 0.0101 0.297 0.297
Echinococcus granulosus voltage gated potassium channel 0.0029 0.0588 0.0588
Toxoplasma gondii exonuclease III APE 0.0023 0.0396 0.0396
Trypanosoma brucei ABC transporter, mitochondrial, putative 0.0101 0.297 0.8846
Echinococcus multilocularis 0.0101 0.297 0.297

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 0.5623 uM PubChem BioAssay. qHTS of TDP-43 Inhibitors. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 2.5119 uM PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 2.9093 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 3.5481 uM PubChem BioAssay. qHTS for Activators of Integrin-Mediated Alleviation for Muscular Dystrophy. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 4.2284 uM PubChem BioAssay. qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 10 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 15.8489 um PUBCHEM_BIOASSAY: qHTS Fluorescence Polarization Assay for Inhibitors of MLL CXXC domain - DNA interaction. (Class of assay: confirmatory) [Related pubchem assays: 2698 (Summary assay.)] ChEMBL. No reference
Potency (functional) 18.526 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 20.7865 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 37.933 uM PUBCHEM_BIOASSAY: qHTS profiling assay for firefly luciferase inhibitor/activator using purified enzyme and Km concentrations of substrates (counterscreen for miR-21 project). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2288, AID2289, AID2598, AID411] ChEMBL. No reference
Potency (functional) 63.0957 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of BAZ2B. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504391] ChEMBL. No reference
Potency (functional) 125.8925 uM PubChem BioAssay. qHTS of PTHR Inhibitors: Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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