Detailed information for compound 1482027

Basic information

Technical information
  • TDR Targets ID: 1482027
  • Name: 2-[[5-(2-dimethylamino-2-oxoethyl)sulfanyl-2- phenyl-1,2,4-triazol-3-yl]sulfanyl]-N,N-dimet hylacetamide
  • MW: 379.5 | Formula: C16H21N5O2S2
  • H donors: 0 H acceptors: 4 LogP: 2.41 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN(C(=O)CSc1nc(n(n1)c1ccccc1)SCC(=O)N(C)C)C
  • InChi: 1S/C16H21N5O2S2/c1-19(2)13(22)10-24-15-17-16(25-11-14(23)20(3)4)21(18-15)12-8-6-5-7-9-12/h5-9H,10-11H2,1-4H3
  • InChiKey: BUTDMAGBNWSGCC-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 2-[[5-(2-dimethylamino-2-oxo-ethyl)sulfanyl-2-phenyl-1,2,4-triazol-3-yl]sulfanyl]-N,N-dimethyl-acetamide
  • 2-[[5-[(2-dimethylamino-2-oxoethyl)thio]-2-phenyl-1,2,4-triazol-3-yl]thio]-N,N-dimethylacetamide
  • 2-[[5-[(2-dimethylamino-2-keto-ethyl)thio]-2-phenyl-1,2,4-triazol-3-yl]thio]-N,N-dimethyl-acetamide
  • 2-[[5-(2-dimethylamino-2-oxo-ethyl)sulfanyl-2-phenyl-1,2,4-triazol-3-yl]sulfanyl]-N,N-dimethyl-ethanamide
  • 2,2'-[(1-phenyl-1H-1,2,4-triazole-3,5-diyl)bis(thio)]bis(N,N-dimethylacetamide)
  • MLS000099972
  • SMR000081177
  • ST5437618
  • ZINC00643500
  • AO-080/42479463

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens ATPase family, AAA domain containing 5 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core Get druggable targets OG5_139225 All targets in OG5_139225
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi larval opioid receptor 0.0051 0.0344 0.0693
Echinococcus multilocularis synaptic vesicle 2 protein 0.0029 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0051 0.0344 0.075
Schistosoma mansoni biogenic amine receptor 0.0051 0.0344 0.0475
Toxoplasma gondii PHD-finger domain-containing protein 0.0145 0.1314 0.2134
Loa Loa (eye worm) hypothetical protein 0.0047 0.0297 0.0648
Schistosoma mansoni biogenic amine (5HT) receptor 0.0051 0.0344 0.0475
Loa Loa (eye worm) hypothetical protein 0.0051 0.0339 0.074
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0062 0.046 0.0633
Echinococcus multilocularis sex peptide receptor 0.0051 0.0344 0.0344
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0024 0.0062 0.0068
Plasmodium falciparum calcium-dependent protein kinase 3 0.0064 0.0473 0.0525
Echinococcus granulosus biogenic amine 5HT receptor 0.0051 0.0344 0.0475
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0047 0.0295 0.0398
Echinococcus multilocularis peregrin 0.0147 0.134 0.134
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0113 0.0982 0.7275
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0047 0.0301 0.0408
Schistosoma mansoni 6-phosphofructokinase 0.0113 0.0982 0.1354
Onchocerca volvulus 0.0029 0.0114 0.0108
Schistosoma mansoni sugar transporter 0.0029 0.0114 0.0157
Brugia malayi 6-phosphofructokinase 0.0113 0.0982 0.2044
Brugia malayi lysyl-tRNA synthetase 0.0046 0.0293 0.0584
Echinococcus multilocularis neuropeptide s receptor 0.0051 0.0344 0.0344
Entamoeba histolytica protein kinase, putative 0.0064 0.0473 0.1546
Schistosoma mansoni neuropeptide receptor 0.0051 0.0344 0.0475
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0114 0.0328
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.0344 0.0344
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0029 0.0114 0.0841
Schistosoma mansoni metabotropic glutamate receptor 0.0089 0.0738 0.1016
Entamoeba histolytica hypothetical protein 0.0046 0.0293 0.0935
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.0982 0.3275
Loa Loa (eye worm) hypothetical protein 0.0051 0.0344 0.075
Brugia malayi AKH receptor 0.0051 0.0344 0.0693
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0114 0.0328
Brugia malayi Serotonin receptor 0.0051 0.0344 0.0693
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0303 0.2964 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.0344 0.0344
Plasmodium falciparum mitogen-activated protein kinase 2 0.0337 0.3312 0.3676
Echinococcus granulosus solute carrier family 22 0.0029 0.0114 0.0157
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0047 0.0295 0.2876
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0113 0.0982 0.7146
Echinococcus multilocularis General substrate transporter 0.0179 0.1672 0.1672
Schistosoma mansoni lysyl-tRNA synthetase 0.0046 0.0293 0.0404
Schistosoma mansoni adenoreceptor 0.0051 0.0344 0.0475
Brugia malayi hypothetical protein 0.0051 0.0344 0.0693
Loa Loa (eye worm) hypothetical protein 0.0051 0.0344 0.075
Echinococcus granulosus neuropeptides capa receptor 0.0051 0.0344 0.0475
Trypanosoma brucei glucose transporter, putative 0.0065 0.0481 0.4808
Echinococcus granulosus dnaJ subfamily B 0.0424 0.4224 0.582
Brugia malayi G protein-coupled receptor F59B2.13 0.0051 0.0344 0.0693
Schistosoma mansoni opsin-like receptor 0.0051 0.0344 0.0475
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0039 0.022 0.1628
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0481 0.1575
Toxoplasma gondii sugar transporter ST3 0.0029 0.0114 0.0089
Onchocerca volvulus 0.0051 0.0344 0.0617
Entamoeba histolytica phosphofructokinase, putative 0.0113 0.0982 0.3275
Loa Loa (eye worm) hypothetical protein 0.0051 0.0344 0.075
Echinococcus multilocularis GPCR, family 3, C terminal 0.003 0.0118 0.0118
Brugia malayi hypothetical protein 0.0459 0.459 0.9684
Echinococcus granulosus General substrate transporter 0.0179 0.1672 0.2304
Loa Loa (eye worm) hypothetical protein 0.0051 0.0344 0.075
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0029 0.0114 0.0841
Schistosoma mansoni lysyl-tRNA synthetase 0.0046 0.0293 0.0404
Loa Loa (eye worm) hypothetical protein 0.0018 0 0.0001
Trichomonas vaginalis CAMK family protein kinase 0.0064 0.0473 0.1546
Loa Loa (eye worm) hypothetical protein 0.0051 0.0344 0.075
Schistosoma mansoni growth hormone secretagogue receptor 0.0051 0.0344 0.0475
Echinococcus granulosus tm gpcr rhodopsin 0.0051 0.0344 0.0475
Loa Loa (eye worm) hypothetical protein 0.0051 0.0344 0.075
Brugia malayi hypothetical protein 0.0051 0.0344 0.0693
Onchocerca volvulus Neuropeptide F receptor homolog 0.0051 0.0344 0.0617
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0337 0.3312 0.5535
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0474 0.4739 0.4739
Echinococcus granulosus lysine specific demethylase 5A 0.0179 0.1669 0.23
Schistosoma mansoni glucose transport protein 0.0208 0.1977 0.2724
Echinococcus multilocularis neuropeptide receptor 0.0051 0.0344 0.0344
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0051 0.0344 0.0475
Entamoeba histolytica protein kinase, putative 0.0064 0.0473 0.1546
Trichomonas vaginalis glucose transporter, putative 0.0029 0.0114 0.0328
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0051 0.0344 0.0344
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.005 0.0333 0.0459
Echinococcus multilocularis neuropeptide receptor 0.0051 0.0344 0.0344
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0052 0.0347 0.0698
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0114 0.0328
Loa Loa (eye worm) jmjC domain-containing protein 0.0299 0.2917 0.6356
Loa Loa (eye worm) hypothetical protein 0.0051 0.0344 0.075
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0037 0.0197 0.0197
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0051 0.0344 0.0475
Echinococcus granulosus neuropeptide receptor A26 0.0051 0.0344 0.0475
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0051 0.0344 0.0693
Loa Loa (eye worm) hypothetical protein 0.0459 0.459 1
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0065 0.0493
Loa Loa (eye worm) hypothetical protein 0.0042 0.0249 0.0542
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0051 0.0344 0.0344
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0065 0.0479
Loa Loa (eye worm) PHD-finger family protein 0.0145 0.1314 0.2864
Loa Loa (eye worm) hypothetical protein 0.0029 0.0114 0.0248
Schistosoma mansoni jumonji domain containing protein 0.0047 0.0295 0.0406
Echinococcus granulosus g protein coupled receptor 0.0051 0.0344 0.0475
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0039 0.022 0.123
Echinococcus multilocularis lysyl tRNA synthetase 0.0046 0.0293 0.0293
Plasmodium falciparum lysine--tRNA ligase 0.0046 0.0293 0.0325
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0065 0.0101
Schistosoma mansoni sugar transporter 0.0029 0.0114 0.0157
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0113 0.0982 1
Onchocerca volvulus 0.0051 0.0344 0.0617
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0114 0.0328
Entamoeba histolytica hypothetical protein 0.0024 0.0062 0.015
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0481 0.1575
Trypanosoma brucei glucose transporter 1E 0.0065 0.0481 0.4808
Brugia malayi Calcitonin receptor-like protein seb-1 0.0052 0.0347 0.0698
Echinococcus granulosus g protein coupled receptor 0.0051 0.0344 0.0475
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0344 0.0475
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0064 0.0473 0.0652
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0126 0.0369
Brugia malayi jmjC domain containing protein 0.0047 0.0295 0.0588
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0051 0.0344 0.0475
Schistosoma mansoni cpg binding protein 0.003 0.0119 0.0164
Loa Loa (eye worm) hypothetical protein 0.0029 0.0114 0.0248
Brugia malayi RE15519p 0.0051 0.0344 0.0693
Echinococcus multilocularis phd:f box containing protein 0.0047 0.0295 0.0295
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0051 0.0344 0.0475
Plasmodium vivax hypothetical protein, conserved 0.0049 0.032 0.0355
Loa Loa (eye worm) hypothetical protein 0.0051 0.0344 0.075
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0051 0.0344 0.0475
Schistosoma mansoni glucose transport protein 0.0208 0.1977 0.2724
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0073 0.0567 0.5698
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0065 0.0101
Entamoeba histolytica phosphofructokinase, putative 0.0113 0.0982 0.3275
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.0038
Schistosoma mansoni hypothetical protein 0.0051 0.0344 0.0475
Loa Loa (eye worm) hypothetical protein 0.0051 0.0338 0.0735
Loa Loa (eye worm) hypothetical protein 0.0035 0.0177 0.0386
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0051 0.0344 0.0693
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0051 0.0344 0.0475
Loa Loa (eye worm) hypothetical protein 0.0073 0.0573 0.1247
Brugia malayi metabotropic glutamate receptor type 2 0.0089 0.0738 0.1525
Schistosoma mansoni amine GPCR 0.0051 0.0344 0.0475
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0114 0.0328
Onchocerca volvulus Huntingtin homolog 0.0127 0.1132 0.2357
Echinococcus granulosus cpg binding protein 0.0033 0.0157 0.0217
Schistosoma mansoni amine GPCR 0.0051 0.0344 0.0475
Schistosoma mansoni bromodomain containing protein 0.0067 0.051 0.0703
Echinococcus granulosus 6 phosphofructokinase 0.0113 0.0982 0.1354
Toxoplasma gondii sugar transporter ST1 0.0029 0.0114 0.0089
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0047 0.0297 0.0648
Giardia lamblia Lysyl-tRNA synthetase 0.0046 0.0293 0.0935
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0208 0.1977 0.1977
Mycobacterium ulcerans sugar transporter 0.0029 0.0114 0.0841
Trichomonas vaginalis conserved hypothetical protein 0.0208 0.1977 0.665
Echinococcus multilocularis neuropeptide FF receptor 2 0.0051 0.0344 0.0344
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0113 0.0982 0.3226
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0064 0.0473 0.0652
Giardia lamblia Prolyl-tRNA synthetase 0.0062 0.046 0.15
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0073 0.0567 0.5698
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0481 0.1575
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0026 0.0076 0.0166
Echinococcus granulosus orexin receptor type 2 0.0051 0.0344 0.0475
Brugia malayi hypothetical protein 0.0051 0.0344 0.0693
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0073 0.0567 0.5698
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.0344 0.0475
Echinococcus granulosus neuropeptide receptor 0.0051 0.0344 0.0475
Loa Loa (eye worm) hypothetical protein 0.003 0.0118 0.0258
Onchocerca volvulus 0.0029 0.0114 0.0108
Trichomonas vaginalis 6-phosphofructokinase, putative 0.003 0.0126 0.0369
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0065 0.0162
Loa Loa (eye worm) jmjC domain-containing protein 0.0047 0.0295 0.0643
Onchocerca volvulus 0.0051 0.0344 0.0617
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0051 0.0344 0.0344
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0062 0.046 0.046
Schistosoma mansoni hypothetical protein 0.0051 0.0344 0.0475
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0051 0.0344 0.0475
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0037 0.0197 0.0271
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0051 0.0344 0.0693
Loa Loa (eye worm) runx1 0.0058 0.0409 0.0891
Echinococcus multilocularis serotonin receptor 0.0051 0.0344 0.0344
Brugia malayi GnHR receptor homolog 0.0051 0.0344 0.0693
Onchocerca volvulus 0.0051 0.0344 0.0617
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0114 0.0328
Echinococcus multilocularis g-protein coupled receptor 0.0051 0.0344 0.0344
Trypanosoma brucei hypothetical protein, conserved 0.0024 0.0062 0.0457
Schistosoma mansoni protein kinase 0.0064 0.0473 0.0652
Brugia malayi Metabotropic glutamate receptor precursor. 0.0183 0.1714 0.3593
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0064 0.0473 0.472
Loa Loa (eye worm) 6-phosphofructokinase 0.0113 0.0982 0.214
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0046 0.0293 0.1796
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0344 0.0475
Toxoplasma gondii phosphofructokinase PFKII 0.003 0.0126 0.011
Brugia malayi follicle stimulating hormone receptor 0.0051 0.0344 0.0693
Echinococcus multilocularis neuropeptides capa receptor 0.0051 0.0344 0.0344
Echinococcus granulosus dro:myosuppressin receptor 0.0051 0.0344 0.0475
Loa Loa (eye worm) hypothetical protein 0.0029 0.0114 0.0248
Loa Loa (eye worm) hypothetical protein 0.0029 0.0114 0.0248
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0344 0.0475
Trypanosoma brucei glucose transporter, putative 0.0065 0.0481 0.4808
Brugia malayi hypothetical protein 0.0051 0.0344 0.0693
Leishmania major glucose transporter, lmgt1 0.0065 0.0481 0.4808
Schistosoma mansoni hypothetical protein 0.0035 0.0177 0.0244
Loa Loa (eye worm) hypothetical protein 0.0051 0.0344 0.075
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0114 0.0328
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0303 0.2964 1
Echinococcus multilocularis neuropeptides capa receptor 0.0051 0.0344 0.0344
Brugia malayi phosphofructokinase 0.0113 0.0982 0.2044
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0051 0.0344 0.0475
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0047 0.0295 0.2876
Loa Loa (eye worm) hypothetical protein 0.0029 0.0114 0.0248
Loa Loa (eye worm) glutamate receptor 0.0183 0.1714 0.3735
Loa Loa (eye worm) hypothetical protein 0.0225 0.2154 0.4694
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0126 0.014
Brugia malayi Sugar transporter family protein 0.0029 0.0114 0.0204
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0114 0.0328
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0046 0.0293 0.2168
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0114 0.0328
Loa Loa (eye worm) hypothetical protein 0.0051 0.0344 0.075
Loa Loa (eye worm) hypothetical protein 0.0051 0.0344 0.075
Giardia lamblia Hexose transporter 0.0029 0.0114 0.0328
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0344 0.0475
Echinococcus multilocularis dro:myosuppressin receptor 0.0051 0.0344 0.0344
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0051 0.0344 0.0344
Brugia malayi hypothetical protein 0.0051 0.0344 0.0693
Brugia malayi Bromodomain containing protein 0.0147 0.134 0.2801
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0025 0.0065 0.0479
Leishmania major hypothetical protein, conserved 0.0029 0.0114 0.1
Toxoplasma gondii lysine-tRNA ligase 0.0046 0.0293 0.0394
Echinococcus granulosus G protein coupled receptor 139 0.0051 0.0344 0.0475
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0073 0.0567 0.5698
Onchocerca volvulus 0.003 0.0119 0.012
Plasmodium falciparum calcium-dependent protein kinase 1 0.0064 0.0473 0.0525
Echinococcus granulosus phd:f box containing protein 0.0047 0.0295 0.0406
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0051 0.0344 0.0475
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0148 0.135 1
Echinococcus granulosus fetal alzheimer antigen falz 0.0025 0.007 0.0097
Echinococcus granulosus microtubule associated protein 2 0.0716 0.7258 1
Chlamydia trachomatis lysine--tRNA ligase 0.0046 0.0293 1
Loa Loa (eye worm) hypothetical protein 0.0062 0.046 0.1001
Schistosoma mansoni hypothetical protein 0.0208 0.1977 0.2724
Brugia malayi metabotropic GABA-B receptor subtype 2 0.003 0.0118 0.0214
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0047 0.0295 0.0398
Toxoplasma gondii transporter, major facilitator family protein 0.0029 0.0114 0.0089
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0051 0.0344 0.0475
Onchocerca volvulus 0.0029 0.0114 0.0108
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0126 0.014
Loa Loa (eye worm) hypothetical protein 0.0018 0 0.0001
Mycobacterium ulcerans integral membrane transport protein 0.0029 0.0114 0.0841
Loa Loa (eye worm) hypothetical protein 0.0029 0.0114 0.0248
Loa Loa (eye worm) hypothetical protein 0.0051 0.0344 0.075
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.002 0.0017 0.0127
Echinococcus granulosus g protein coupled receptor 0.0051 0.0344 0.0475
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0148 0.135 1
Onchocerca volvulus 0.0029 0.0114 0.0108
Schistosoma mansoni neuropeptide receptor 0.0051 0.0344 0.0475
Loa Loa (eye worm) jmjC domain-containing protein 0.0047 0.0295 0.0643
Loa Loa (eye worm) hypothetical protein 0.004 0.0223 0.0487
Trypanosoma brucei glucose transporter, putative 0.0065 0.0481 0.4808
Brugia malayi putative neuropeptide receptor 0.0051 0.0344 0.0693
Loa Loa (eye worm) hypothetical protein 0.0051 0.0344 0.075
Schistosoma mansoni hypothetical protein 0.0145 0.1314 0.1811
Loa Loa (eye worm) hypothetical protein 0.0029 0.0114 0.0248
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0024 0.0062 0.0453
Loa Loa (eye worm) hypothetical protein 0.0051 0.0344 0.075
Loa Loa (eye worm) hypothetical protein 0.0029 0.0114 0.0248
Echinococcus granulosus 7tm_1 domain containing protein 0.0051 0.0344 0.0475
Loa Loa (eye worm) hypothetical protein 0.0127 0.1132 0.2465
Onchocerca volvulus 0.0051 0.0344 0.0617
Echinococcus multilocularis microtubule associated protein 2 0.0716 0.7258 0.7258
Brugia malayi Major Facilitator Superfamily protein 0.0029 0.0114 0.0204
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0064 0.0473 0.0701
Trypanosoma cruzi hexose transporter, putative 0.0065 0.0481 0.4808
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0114 0.0328
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0126 0.014
Brugia malayi jmjC domain containing protein 0.0474 0.4739 1
Brugia malayi Bromodomain containing protein 0.0079 0.0636 0.1311
Schistosoma mansoni hypothetical protein 0.0051 0.0344 0.0475
Loa Loa (eye worm) hypothetical protein 0.0062 0.046 0.1001
Echinococcus multilocularis orexin receptor type 2 0.0051 0.0344 0.0344
Brugia malayi PHD-finger family protein 0.0051 0.0339 0.0682
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0063 0.0467 0.0643
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0126 0.4297
Loa Loa (eye worm) jmjC domain-containing protein 0.0047 0.0295 0.0643
Brugia malayi Dopamine receptor protein 1 0.0051 0.0344 0.0693
Loa Loa (eye worm) hypothetical protein 0.0051 0.0344 0.075
Brugia malayi hypothetical protein 0.0051 0.0344 0.0693
Echinococcus granulosus lysyl tRNA synthetase 0.0046 0.0293 0.0404
Onchocerca volvulus 0.0051 0.0344 0.0617
Echinococcus granulosus Sugar transporter ERD6 protein 0.0029 0.0114 0.0157
Plasmodium falciparum calcium-dependent protein kinase 2 0.0064 0.0473 0.0525
Brugia malayi F/Y-rich N-terminus family protein 0.0058 0.0416 0.0845
Echinococcus granulosus 7TM GPCR rhodopsin 0.0051 0.0344 0.0475
Schistosoma mansoni jumonji/arid domain-containing protein 0.0179 0.1669 0.23
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0126 0.014
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0064 0.0473 0.0965
Trichomonas vaginalis glucose transporter, putative 0.0065 0.0481 0.1575
Loa Loa (eye worm) hypothetical protein 0.0064 0.0473 0.103
Brugia malayi Melatonin receptor type 1A 0.0051 0.0344 0.0693
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.003 0.0126 0.0369
Brugia malayi Sugar transporter family protein 0.0208 0.1977 0.415
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0064 0.0473 0.103
Echinococcus multilocularis solute carrier family 22 0.0029 0.0114 0.0114
Toxoplasma gondii sugar transporter ST2 0.0029 0.0114 0.0089
Brugia malayi hypothetical protein 0.0051 0.0344 0.0693
Loa Loa (eye worm) glutamate receptor 0.0072 0.0559 0.1217
Schistosoma mansoni neuropeptide receptor 0.0051 0.0344 0.0475
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0065 0.0101
Echinococcus granulosus tm gpcr rhodopsin 0.0051 0.0344 0.0475
Loa Loa (eye worm) hypothetical protein 0.0051 0.0344 0.075
Echinococcus multilocularis serotonin receptor 0.0051 0.0344 0.0344
Onchocerca volvulus 0.0029 0.0114 0.0108
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0062 0.046 0.15
Loa Loa (eye worm) hypothetical protein 0.0029 0.0114 0.0248
Onchocerca volvulus 0.0029 0.0114 0.0108
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0051 0.0344 0.0344
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0114 0.0328
Trypanosoma cruzi hexose transporter, putative 0.0065 0.0481 0.4808
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0064 0.0473 0.0473
Schistosoma mansoni amine GPCR 0.0051 0.0344 0.0475
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.003 0.0126 0.0369
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0051 0.0344 0.0475
Schistosoma mansoni myosin xvIII 0.0051 0.0344 0.0475
Loa Loa (eye worm) hypothetical protein 0.0018 0 0.0001
Onchocerca volvulus 0.0029 0.0114 0.0108
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0114 0.0328
Brugia malayi hypothetical protein 0.0127 0.1132 0.2359
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0017 0.0127
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0062 0.046 0.15
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0025 0.007 0.007
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0114 0.0328
Schistosoma mansoni zinc finger protein 0.0022 0.0038 0.0053
Onchocerca volvulus 0.0051 0.0344 0.0617
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0041 0.0233 0.0733
Schistosoma mansoni serine/threonine protein kinase 0.0064 0.0473 0.0652
Giardia lamblia PHD finger protein 15 0.0145 0.1314 0.4402
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.003 0.0126 0.0298
Echinococcus multilocularis fmrfamide receptor 0.0051 0.0344 0.0344
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0051 0.0344 0.0344
Echinococcus granulosus peregrin 0.0147 0.134 0.1846
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0025 0.007 0.0097
Loa Loa (eye worm) hypothetical protein 0.0029 0.0114 0.0248
Onchocerca volvulus Putative transporter 0.0029 0.0114 0.0108
Schistosoma mansoni sugar transporter 0.0029 0.0114 0.0157
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.0344 0.0475
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0047 0.0301 0.294
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0065 0.0493
Schistosoma mansoni phosphatidylserine receptor 0.0047 0.0295 0.0406
Loa Loa (eye worm) G-protein coupled receptor 0.0051 0.0344 0.075
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0114 0.0328
Schistosoma mansoni hypothetical protein 0.0424 0.4224 0.582
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0064 0.0471 0.0649
Schistosoma mansoni biogenic amine (5HT) receptor 0.0051 0.0344 0.0475
Trypanosoma brucei glucose transporter, putative 0.0065 0.0481 0.4808
Loa Loa (eye worm) hypothetical protein 0.0051 0.0344 0.075
Loa Loa (eye worm) hypothetical protein 0.0051 0.0344 0.075
Echinococcus multilocularis calcium dependent protein kinase 0.006 0.0432 0.0432
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0052 0.0347 0.0757
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0114 0.0328
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.0344 0.0475
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0481 0.1575
Echinococcus granulosus tachykinin peptides receptor 99D 0.0051 0.0344 0.0475
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0114 0.0328
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0051 0.0344 0.0475
Echinococcus multilocularis g protein coupled receptor 0.0051 0.0344 0.0344
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0051 0.0344 0.0475
Loa Loa (eye worm) hypothetical protein 0.0051 0.0344 0.075
Echinococcus granulosus neuropeptides capa receptor 0.0051 0.0344 0.0475
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0114 0.0328
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0051 0.0344 0.075
Echinococcus granulosus peptide allatostatin:somatostatin 0.0051 0.0344 0.0475
Schistosoma mansoni DNA polymerase eta 0.002 0.0017 0.0024
Echinococcus multilocularis L aminoadipate semialdehyde 0.0086 0.0707 0.0707
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0126 0.0369
Plasmodium falciparum protein kinase 6 0.0884 0.901 1
Echinococcus granulosus neuropeptide Y receptor 0.0051 0.0344 0.0475
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0064 0.0473 0.0473
Leishmania major phosphopantetheinyl transferase-like protein 0.0024 0.0062 0.0457
Schistosoma mansoni histamine h1 receptor 0.0051 0.0344 0.0475
Loa Loa (eye worm) hypothetical protein 0.0459 0.459 1
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0051 0.0344 0.075
Schistosoma mansoni biogenic amine receptor 0.0051 0.0344 0.0475
Onchocerca volvulus 0.0051 0.0344 0.0617
Toxoplasma gondii 6-phosphofructokinase 0.003 0.0126 0.011
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0303 0.2964 1
Plasmodium falciparum calcium-dependent protein kinase 5 0.0064 0.0473 0.0525
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0303 0.2964 1
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0166 0.1535 0.3214
Loa Loa (eye worm) hypothetical protein 0.0051 0.0344 0.075
Loa Loa (eye worm) hypothetical protein 0.0051 0.0344 0.075
Loa Loa (eye worm) hypothetical protein 0.0145 0.1314 0.2864
Onchocerca volvulus Poor gastrulation protein homolog 0.003 0.0118 0.0118
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0303 0.2964 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.0344 0.0475
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0051 0.0344 0.075
Leishmania major glucose transporter, lmgt3 0.0065 0.0481 0.4808
Schistosoma mansoni biogenic amine receptor 0.0051 0.0344 0.0475
Giardia lamblia Fructose-bisphosphate aldolase 0.0303 0.2964 1
Schistosoma mansoni jumonji/arid domain-containing protein 0.0179 0.1669 0.23
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0126 0.4297
Echinococcus granulosus neuropeptide FF receptor 2 0.0051 0.0344 0.0475
Echinococcus multilocularis 6 phosphofructokinase 0.0113 0.0982 0.0982
Onchocerca volvulus 0.0051 0.0344 0.0617
Schistosoma mansoni opsin-like receptor 0.0051 0.0344 0.0475
Mycobacterium ulcerans 6-phosphofructokinase 0.0113 0.0982 0.7275
Brugia malayi Serotonin receptor 0.0051 0.0344 0.0693
Echinococcus granulosus solute carrier family 22 0.0029 0.0114 0.0157
Brugia malayi Major Facilitator Superfamily protein 0.0029 0.0114 0.0204
Echinococcus multilocularis solute carrier family 22 0.0029 0.0114 0.0114
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0029 0.0114 0.1
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.002 0.0017 0.0024
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.0982 0.3275
Schistosoma mansoni cpg binding protein 0.0033 0.0157 0.0217
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0051 0.0344 0.0344
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0029 0.0114 0.0841
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0051 0.0344 0.0344
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0049 0.032 0.0355
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0208 0.1975 0.2722
Toxoplasma gondii protein kinase, putative 0.0589 0.5934 1
Echinococcus granulosus solute carrier family 22 0.0029 0.0114 0.0157
Echinococcus granulosus JmjC domain containing protein 4 0.0047 0.0295 0.0406
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0114 0.0328
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0051 0.0344 0.0475
Trypanosoma cruzi hexose transporter, putative 0.0029 0.0114 0.1
Brugia malayi hypothetical protein 0.0029 0.0114 0.0204
Echinococcus multilocularis solute carrier family 22 0.0029 0.0114 0.0114
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0024 0.0062 0.0453
Echinococcus granulosus zinc finger protein 0.0022 0.0038 0.0053
Schistosoma mansoni neuropeptide f receptor 76f 0.0051 0.0344 0.0475
Loa Loa (eye worm) melatonin receptor type 1A 0.0051 0.0344 0.075
Echinococcus multilocularis solute carrier family 22 0.0029 0.0114 0.0114
Schistosoma mansoni protein kinase 0.0064 0.0473 0.0652
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.0344 0.0344
Schistosoma mansoni cpg binding protein 0.0033 0.0157 0.0217
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0114 0.0328
Onchocerca volvulus 0.0051 0.0344 0.0617
Onchocerca volvulus 0.0051 0.0344 0.0617
Loa Loa (eye worm) hypothetical protein 0.0018 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0051 0.0344 0.075
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.0982 0.3275
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0208 0.1977 0.1977
Trypanosoma brucei THT1 - hexose transporter, putative 0.0065 0.0481 0.4808
Loa Loa (eye worm) hypothetical protein 0.0051 0.0344 0.075
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0344 0.0475
Leishmania major glucose transporter/membrane transporter D2, putative 0.0065 0.0481 0.4808
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0024 0.0062 0.0068
Echinococcus granulosus sex peptide receptor 0.0051 0.0344 0.0475
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0051 0.0344 0.0475
Echinococcus multilocularis jumonji domain containing 1A 0.0047 0.0295 0.0295
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0046 0.0293 0.2856
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0114 0.0328
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0064 0.0473 0.0701
Echinococcus granulosus alpha 1A adrenergic receptor 0.0051 0.0344 0.0475
Echinococcus multilocularis lysine specific demethylase 5A 0.0175 0.1631 0.1631
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.005 0.0333 0.0333
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0073 0.0567 0.5698
Schistosoma mansoni hypothetical protein 0.0047 0.0301 0.0415
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0062 0.046 0.0936
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0047 0.0297 0.0648
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0148 0.135 1
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0114 0.0328
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0051 0.0344 0.0475
Trichomonas vaginalis glucose transporter, putative 0.0065 0.0481 0.1575
Echinococcus granulosus metabotropic glutamate receptor 2 0.0153 0.1405 0.1936
Brugia malayi Bromodomain containing protein 0.004 0.0223 0.0434
Schistosoma mansoni neuropeptide F-like receptor 0.0051 0.0344 0.0475
Schistosoma mansoni alpha-1 adrenergic receptor 0.0051 0.0344 0.0475
Plasmodium vivax calcium-dependent protein kinase, putative 0.0064 0.0473 0.0525
Loa Loa (eye worm) hypothetical protein 0.0051 0.0344 0.075
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.002 0.0017 0.0038
Echinococcus granulosus neuropeptide receptor 0.0051 0.0344 0.0475
Plasmodium vivax hexose transporter 0.0208 0.1977 0.2194
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0208 0.1977 0.2724
Toxoplasma gondii facilitative glucose transporter GT1 0.0208 0.1977 0.3262
Loa Loa (eye worm) hypothetical protein 0.0029 0.0114 0.0248
Plasmodium vivax CDK-related protein kinase 6, putative 0.0884 0.901 1
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0474 0.4739 0.653
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.0344 0.0344
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0051 0.0344 0.0344
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0029 0.0114 0.0157
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0051 0.0344 0.0344
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0064 0.0473 0.0652
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0065 0.0479
Echinococcus granulosus metabotropic glutamate receptor 5 0.0225 0.2154 0.2968
Loa Loa (eye worm) neuropeptide F receptor 0.0051 0.0344 0.075
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0046 0.0293 0.2856
Brugia malayi G-protein coupled receptor 0.0051 0.0344 0.0693
Echinococcus granulosus solute carrier family 22 0.0029 0.0114 0.0157
Plasmodium vivax proline--tRNA ligase, putative 0.0073 0.0567 0.0629
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0029 0.0114 1
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0114 0.0328
Trypanosoma cruzi sugar transporter, putative 0.0029 0.0114 0.1
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.0344 0.0475
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0113 0.0982 1
Schistosoma mansoni sugar transporter 0.0029 0.0114 0.0157
Brugia malayi jmjC domain containing protein 0.0179 0.1669 0.3499
Toxoplasma gondii PHD-finger domain-containing protein 0.0145 0.1314 0.2134
Brugia malayi neuropeptide F receptor 0.0051 0.0344 0.0693
Echinococcus multilocularis dnaJ subfamily B 0.0424 0.4224 0.4224
Leishmania major glucose transporter, lmgt2 0.0065 0.0481 0.4808
Loa Loa (eye worm) major facilitator superfamily transporter 0.0029 0.0114 0.0248
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0126 0.0369
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0051 0.0344 0.0344
Brugia malayi sulfakinin receptor protein 0.0051 0.0344 0.0693
Loa Loa (eye worm) hypothetical protein 0.0025 0.0065 0.0142
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0047 0.0295 0.0406
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0064 0.0471 0.0471
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0051 0.0344 0.0693
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0064 0.0473 0.0525
Plasmodium vivax JmjC domain containing protein 0.0047 0.0295 0.0327
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0062 0.046 0.0936
Leishmania major hypothetical protein, conserved 0.0047 0.0295 0.2876
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0119 0.026
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.0344 0.0344
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.0982 0.3275
Trypanosoma brucei THT1 - hexose transporter, putative 0.0065 0.0481 0.4808
Loa Loa (eye worm) hypothetical protein 0.0051 0.0344 0.075
Loa Loa (eye worm) jmjC domain-containing protein 0.0179 0.1669 0.3637
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0051 0.0344 0.0344
Trypanosoma brucei glucose transporter, putative 0.0065 0.0481 0.4808
Echinococcus granulosus hypothetical protein 0.0051 0.0344 0.0475
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0114 0.0328
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0051 0.0344 0.0475
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.0344 0.0344
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0114 0.0328
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.002 0.0017 0.0017
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0051 0.0344 0.0344
Echinococcus multilocularis Protein lozenge 0.0058 0.0409 0.0409
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0029 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0051 0.0344 0.075
Trichomonas vaginalis sugar transport protein, putative 0.0029 0.0114 0.0328
Onchocerca volvulus 0.0029 0.0114 0.0108
Entamoeba histolytica acyl-coA synthetase, putative 0.0025 0.0065 0.0162
Onchocerca volvulus Metabotropic glutamate receptor homolog 0.003 0.0118 0.0118
Loa Loa (eye worm) hypothetical protein 0.0047 0.0295 0.0643
Echinococcus multilocularis fmrfamide receptor 0.0051 0.0344 0.0344
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0032 0.0069
Brugia malayi AF-10 protein 0.0047 0.0301 0.0601
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0064 0.0473 0.0473
Entamoeba histolytica phosphofructokinase, putative 0.0113 0.0982 0.3275
Schistosoma mansoni neuropeptide F-like receptor 0.0051 0.0344 0.0475
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.002 0.0017 0.0024
Onchocerca volvulus 0.0051 0.0344 0.0617
Echinococcus granulosus dna polymerase kappa 0.002 0.0017 0.0024
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0114 0.0328
Brugia malayi Receptor family ligand binding region containing protein 0.0047 0.0297 0.0593
Schistosoma mansoni neuropeptide receptor 0.0051 0.0344 0.0475
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0303 0.2964 1
Loa Loa (eye worm) hypothetical protein 0.0051 0.0344 0.075
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0029 0.0114 0.0841
Chlamydia trachomatis proline--tRNA ligase 0.0022 0.0039 0.1316
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0208 0.1977 0.2724
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0344 0.0475
Loa Loa (eye worm) hypothetical protein 0.0052 0.0347 0.0757
Onchocerca volvulus Alhambra homolog 0.0145 0.1314 0.2761
Echinococcus multilocularis G-protein coupled receptor, putative 0.0051 0.0344 0.0344
Loa Loa (eye worm) hypothetical protein 0.0051 0.0344 0.075
Trypanosoma brucei glucose transporter, putative 0.0065 0.0481 0.4808
Trypanosoma brucei glucose transporter 2A 0.0065 0.0481 0.4808
Onchocerca volvulus 0.0029 0.0114 0.0108
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0051 0.0344 0.0475
Echinococcus multilocularis somatostatin receptor 0.0051 0.0344 0.0344
Schistosoma mansoni protein kinase 0.0064 0.0473 0.0652
Echinococcus multilocularis lysine specific demethylase 6a 0.0047 0.0295 0.0295
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0046 0.0293 0.0935
Loa Loa (eye worm) hypothetical protein 0.0025 0.0065 0.0142
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0208 0.1977 0.2724
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0051 0.0344 0.075
Loa Loa (eye worm) sugar transporter 0.0029 0.0114 0.0248
Plasmodium vivax sugar transporter, putative 0.0029 0.0114 0.0126
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0064 0.0473 0.0652
Loa Loa (eye worm) hypothetical protein 0.0051 0.0344 0.075
Echinococcus granulosus serotonin receptor 0.0051 0.0344 0.0475
Plasmodium falciparum hexose transporter 0.0208 0.1977 0.2194
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0025 0.0065 0.0479
Echinococcus granulosus jumonji domain containing 1A 0.0047 0.0295 0.0406
Echinococcus multilocularis neuropeptide Y receptor 0.0051 0.0344 0.0344
Brugia malayi hypothetical protein 0.0029 0.0114 0.0204
Loa Loa (eye worm) hypothetical protein 0.0248 0.239 0.5207
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0126 0.0369
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0086 0.0707 0.1459
Echinococcus granulosus lysine specific demethylase 6a 0.0047 0.0295 0.0406
Brugia malayi G-protein coupled receptor 0.0051 0.0344 0.0693
Onchocerca volvulus 0.0051 0.0344 0.0617
Echinococcus granulosus L aminoadipate semialdehyde 0.0086 0.0707 0.0974
Loa Loa (eye worm) hypothetical protein 0.0051 0.0344 0.075
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0025 0.0065 0.0479
Loa Loa (eye worm) hypothetical protein 0.0029 0.0114 0.0248
Brugia malayi 6-phosphofructokinase 0.0113 0.0982 0.2044
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0024 0.0062 0.2091
Schistosoma mansoni metabotropic glutamate receptor 0.0153 0.1405 0.1936
Brugia malayi Cam kinase protein 1 0.0064 0.0473 0.0965
Loa Loa (eye worm) sugar transporter 0.0208 0.1977 0.4307
Onchocerca volvulus 0.0051 0.0344 0.0617
Loa Loa (eye worm) hypothetical protein 0.0051 0.0344 0.075
Loa Loa (eye worm) hypothetical protein 0.0051 0.0344 0.075
Echinococcus multilocularis dna polymerase eta 0.002 0.0017 0.0017
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0062 0.046 0.3088
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0065 0.0162
Brugia malayi jmjC domain containing protein 0.0047 0.0295 0.0588
Schistosoma mansoni terminal deoxycytidyl transferase 0.002 0.0017 0.0024
Brugia malayi Tachykinin-like peptides receptor 99D 0.0051 0.0344 0.0693
Toxoplasma gondii phosphofructokinase domain-containing protein 0.003 0.0126 0.011
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0065 0.0493
Loa Loa (eye worm) hypothetical protein 0.0127 0.1132 0.2465
Echinococcus multilocularis g protein coupled receptor 0.0051 0.0344 0.0344
Schistosoma mansoni phd/f-box containing protein 0.0047 0.0295 0.0406
Echinococcus multilocularis zinc finger protein 0.0022 0.0038 0.0038
Onchocerca volvulus 0.0086 0.0707 0.1418
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0024 0.0062 0.0078
Loa Loa (eye worm) hypothetical protein 0.0051 0.0344 0.075
Loa Loa (eye worm) hypothetical protein 0.0051 0.0344 0.075
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0225 0.2154 0.2154
Echinococcus granulosus biogenic amine 5HT receptor 0.0051 0.0344 0.0475
Loa Loa (eye worm) major facilitator superfamily transporter 0.0029 0.0114 0.0248
Plasmodium falciparum proline--tRNA ligase 0.0073 0.0567 0.0629
Brugia malayi jmjC domain containing protein 0.0047 0.0295 0.0588
Onchocerca volvulus 0.0051 0.0344 0.0617
Schistosoma mansoni jumonji domain containing protein 0.0376 0.3726 0.5134
Echinococcus multilocularis g protein coupled receptor 0.0051 0.0344 0.0344
Trypanosoma brucei THT1 - hexose transporter, putative 0.0065 0.0481 0.4808
Loa Loa (eye worm) hypothetical protein 0.0051 0.0344 0.075
Echinococcus granulosus somatostatin receptor 0.0051 0.0344 0.0475
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0114 0.0328
Echinococcus granulosus fmrfamide receptor 0.0051 0.0344 0.0475
Brugia malayi hypothetical protein 0.0029 0.0114 0.0204
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0114 0.0328
Schistosoma mansoni lozenge 0.0058 0.0409 0.0563
Trypanosoma cruzi hexose transporter, putative 0.0035 0.0177 0.165
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0114 0.0328
Loa Loa (eye worm) hypothetical protein 0.0051 0.0344 0.075
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0208 0.1977 0.1977
Brugia malayi PHD-finger family protein 0.0145 0.1314 0.2747
Trichomonas vaginalis myo-inositol transporter, putative 0.0029 0.0114 0.0328
Onchocerca volvulus 0.0029 0.0114 0.0108
Echinococcus multilocularis JmjC domain containing protein 4 0.0047 0.0295 0.0295
Trypanosoma brucei sugar transporter, putative 0.0029 0.0114 0.1
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0047 0.0295 0.2876
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0051 0.0344 0.075
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0114 0.0328
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.0065 0.0027
Echinococcus granulosus synaptic vesicle 2 protein 0.0029 0.0114 0.0157
Loa Loa (eye worm) neuropeptide F receptor 0.0051 0.0344 0.075
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0064 0.0473 0.0525
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.0344 0.0344
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0114 0.0328
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0029 0.0114 0.0126
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0051 0.0344 0.0693
Brugia malayi Major Facilitator Superfamily protein 0.0029 0.0114 0.0204
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0046 0.0293 0.2168
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0039 0.022 0.1628
Toxoplasma gondii PHD-finger domain-containing protein 0.0047 0.0301 0.0408
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0208 0.1977 0.1977
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0344 0.0475
Loa Loa (eye worm) hypothetical protein 0.0029 0.0114 0.0248
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0064 0.0473 0.0525
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0344 0.0475
Echinococcus granulosus neuropeptide Y receptor 0.0051 0.0344 0.0475
Loa Loa (eye worm) hypothetical protein 0.0029 0.0114 0.0248
Schistosoma mansoni microtubule-associated protein tau 0.0716 0.7258 1
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0114 0.0328
Loa Loa (eye worm) hypothetical protein 0.0018 0 0.0001
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0024 0.0062 0.0453
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.0065 0.0027
Onchocerca volvulus 0.0029 0.0114 0.0108
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0303 0.2964 1
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0153 0.1405 0.1405
Echinococcus multilocularis G protein coupled receptor 139 0.0051 0.0344 0.0344
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0303 0.2964 1
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0126 0.0369
Trypanosoma brucei glucose transporter, putative 0.0065 0.0481 0.4808
Schistosoma mansoni protein phosphatase 2C 0.0047 0.0295 0.0406
Loa Loa (eye worm) hypothetical protein 0.0051 0.0344 0.075
Plasmodium vivax lysine--tRNA ligase, putative 0.0046 0.0293 0.0325
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0064 0.0473 0.0473
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0481 0.1575
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0114 0.0328
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.0344 0.0475
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0051 0.0344 0.0475
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0086 0.0707 0.0974
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0114 0.0328
Echinococcus granulosus GPCR family 3 C terminal 0.003 0.0118 0.0163
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0114 0.0328
Brugia malayi PHD-finger family protein 0.0028 0.0096 0.0166
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0337 0.3312 0.3676
Trypanosoma brucei glucose transporter, putative 0.0065 0.0481 0.4808
Echinococcus multilocularis dna polymerase kappa 0.002 0.0017 0.0017
Toxoplasma gondii histone lysine methyltransferase SET1 0.0059 0.0422 0.0614
Brugia malayi putative neuropeptide receptor NPR1 0.0051 0.0344 0.0693
Schistosoma mansoni 6-phosphofructokinase 0.0113 0.0982 0.1354
Trypanosoma cruzi glucose transporter, putative 0.0029 0.0114 0.1
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0145 0.1314 0.1811
Onchocerca volvulus 0.0051 0.0344 0.0617
Brugia malayi hypothetical protein 0.0051 0.0344 0.0693
Loa Loa (eye worm) hypothetical protein 0.0046 0.0293 0.0638
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0064 0.0473 0.103
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0344 0.0475
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0025 0.0065 0.0479
Plasmodium falciparum JmjC domain-containing protein, putative 0.0047 0.0295 0.0327
Schistosoma mansoni hypothetical protein 0.0051 0.0344 0.0475
Loa Loa (eye worm) hypothetical protein 0.0086 0.0707 0.1539
Schistosoma mansoni amine GPCR 0.0051 0.0344 0.0475
Loa Loa (eye worm) hypothetical protein 0.0046 0.0287 0.0626
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0114 0.0328
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0051 0.0344 0.0617
Echinococcus granulosus jumonji domain containing protein 0.0201 0.1904 0.2623
Schistosoma mansoni glucose transport protein 0.0208 0.1977 0.2724
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0017 0.0127
Onchocerca volvulus 0.0051 0.0344 0.0617
Onchocerca volvulus 0.0029 0.0114 0.0108
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0022 0.0039 0.0285
Loa Loa (eye worm) G-protein coupled receptor 0.0051 0.0344 0.075
Echinococcus multilocularis allatostatin A receptor 0.0051 0.0344 0.0344
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.0344 0.0475
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0114 0.0328
Loa Loa (eye worm) hypothetical protein 0.0051 0.0344 0.075
Loa Loa (eye worm) 6-phosphofructokinase 0.0113 0.0982 0.214
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0064 0.0473 0.0701
Onchocerca volvulus 0.0029 0.0114 0.0108
Echinococcus multilocularis PHD finger protein rhinoceros 0.0145 0.1314 0.1314
Plasmodium falciparum calcium-dependent protein kinase 4 0.0064 0.0473 0.0525
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0025 0.0065 0.0479
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.0344 0.0344
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0303 0.2964 1
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0126 0.0369
Loa Loa (eye worm) hypothetical protein 0.0051 0.0344 0.075
Echinococcus granulosus neuropeptide s receptor 0.0051 0.0344 0.0475
Plasmodium falciparum phd finger protein, putative 0.0145 0.1314 0.1459
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0073 0.0567 0.0861
Loa Loa (eye worm) hypothetical protein 0.0025 0.0065 0.0142
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0303 0.2964 1
Brugia malayi CXXC zinc finger family protein 0.003 0.0119 0.0215
Onchocerca volvulus 0.0029 0.0114 0.0108
Brugia malayi Sugar transporter family protein 0.0029 0.0114 0.0204
Loa Loa (eye worm) hypothetical protein 0.0047 0.0295 0.0643
Schistosoma mansoni amine GPCR 0.0051 0.0344 0.0475
Giardia lamblia Sugar-proton symporter 0.0029 0.0114 0.0328
Schistosoma mansoni hypothetical protein 0.003 0.0118 0.0163
Echinococcus granulosus PHD finger protein rhinoceros 0.0145 0.1314 0.1811
Loa Loa (eye worm) phosphofructokinase 0.0113 0.0982 0.214
Echinococcus multilocularis jumonji domain containing protein 0.0201 0.1904 0.1904
Brugia malayi Dopamine receptor protein 2 0.0051 0.0344 0.0693
Loa Loa (eye worm) hypothetical protein 0.0051 0.0344 0.075
Brugia malayi latrophilin 2 splice variant baaae 0.0035 0.0177 0.0338
Brugia malayi hypothetical protein 0.0051 0.0344 0.0693
Echinococcus granulosus dna polymerase eta 0.002 0.0017 0.0024
Plasmodium vivax hypothetical protein, conserved 0.0145 0.1314 0.1459
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0114 0.0328
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0017 0.0127
Onchocerca volvulus Huntingtin homolog 0.0127 0.1132 0.2357
Echinococcus multilocularis neuropeptide receptor A26 0.0051 0.0344 0.0344
Echinococcus multilocularis neuropeptide Y receptor 0.0051 0.0344 0.0344
Trypanosoma cruzi hexose transporter, putative 0.0065 0.0481 0.4808
Schistosoma mansoni hypothetical protein 0.0021 0.0032 0.0044
Brugia malayi jmjC domain containing protein 0.0047 0.0295 0.0588
Loa Loa (eye worm) hypothetical protein 0.0029 0.0114 0.0248
Loa Loa (eye worm) hypothetical protein 0.0051 0.0344 0.075
Leishmania major protein kinase, putative 0.0064 0.0473 0.472
Trypanosoma cruzi hexose transporter 0.0065 0.0481 0.4808
Brugia malayi major facilitator superfamily protein 0.0029 0.0114 0.0204
Loa Loa (eye worm) hypothetical protein 0.0051 0.0344 0.075
Loa Loa (eye worm) TYRA-2 protein 0.0051 0.0344 0.075
Brugia malayi neuropeptide F receptor 0.0051 0.0344 0.0693
Mycobacterium ulcerans hypothetical protein 0.0025 0.0065 0.0479
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0055 0.0378 0.0521
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0114 0.0328
Plasmodium falciparum protein kinase 7 0.0589 0.5934 0.6586
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0047 0.0301 0.294
Loa Loa (eye worm) hypothetical protein 0.0051 0.0344 0.075
Echinococcus granulosus tm gpcr rhodopsin 0.0051 0.0344 0.0475
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0051 0.0344 0.0344
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0062 0.046 0.0633
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0114 0.0328
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0114 0.0328
Onchocerca volvulus 0.0459 0.459 1
Brugia malayi G protein-coupled receptor 0.0051 0.0344 0.0693
Leishmania major myo-inositol/proton symporter (MIT) 0.0029 0.0114 0.1
Leishmania major lysyl-tRNA synthetase, putative 0.0046 0.0293 0.2856
Echinococcus granulosus g-protein coupled receptor 0.0051 0.0344 0.0475
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0065 0.0479
Leishmania major ATP-dependent phosphofructokinase 0.0113 0.0982 1
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0025 0.0065 0.0479
Brugia malayi ORL1-like opioid receptor 0.0051 0.0344 0.0693
Brugia malayi Dopamine receptor 0.0051 0.0344 0.0693
Onchocerca volvulus 0.0029 0.0114 0.0108
Echinococcus multilocularis cpg binding protein 0.0033 0.0157 0.0157
Echinococcus granulosus calcium dependent protein kinase 0.006 0.0432 0.0595
Treponema pallidum fructose-bisphosphate aldolase 0.0303 0.2964 1
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0062 0.046 0.0633
Loa Loa (eye worm) hypothetical protein 0.0051 0.0344 0.075
Brugia malayi major facilitator superfamily protein 0.0029 0.0114 0.0204
Echinococcus granulosus allatostatin A receptor 0.0051 0.0344 0.0475
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0208 0.1977 0.2724
Schistosoma mansoni opsin-like receptor 0.0051 0.0344 0.0475
Schistosoma mansoni glucose transporter 0.0029 0.0114 0.0157
Brugia malayi hypothetical protein 0.0051 0.0344 0.0693
Onchocerca volvulus 0.0029 0.0114 0.0108

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 1.8356 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] ChEMBL. No reference
Potency (functional) 3.5481 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b: Cytotox Counterscreen. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588855, AID588860] ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: Inhibitors of Regulator of G Protein Signaling (RGS) 4: qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504856] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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