Detailed information for compound 1488960

Basic information

Technical information
  • TDR Targets ID: 1488960
  • Name: 2-(4-piperidyl)ethanol
  • MW: 129.2 | Formula: C7H15NO
  • H donors: 2 H acceptors: 1 LogP: 0.21 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: OCCC1CCNCC1
  • InChi: 1S/C7H15NO/c9-6-3-7-1-4-8-5-2-7/h7-9H,1-6H2
  • InChiKey: LDSQQXKSEFZAPE-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-(4-piperidinyl)ethanol
  • 2-piperidin-4-ylethanol
  • 4-(2-Hydroxyethyl)piperidine
  • 4-Ethanolpiperidine
  • 4-Piperidineethanol
  • EINECS 210-727-7
  • NSC 93818
  • NSC93818
  • o4-Piperidineethanol
  • P46156_ALDRICH

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi histone deacetylase 11 0.0183 0.0597 0.0597
Echinococcus granulosus integrin beta 2 0.1054 0.3786 0.3786
Trypanosoma cruzi btb/poz domain containing protein, putative 0.0068 0.0176 0.0559
Schistosoma mansoni aryl hydrocarbon receptor 0.0042 0.0083 0.0083
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0037 0.0063 0.0063
Schistosoma mansoni hypothetical protein 0.0037 0.0063 0.0063
Giardia lamblia Translation initiation factor eIF-4A, putative 0.0827 0.2956 1
Brugia malayi voltage-dependent calcium channel 0.0094 0.0273 0.0273
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0058 0.0141 0.0439
Onchocerca volvulus 0.0037 0.0063 0.0063
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0094 0.0273 0.0273
Loa Loa (eye worm) PAN domain-containing protein 0.0046 0.0094 0.0094
Trypanosoma cruzi btb/poz domain containing protein, putative 0.0068 0.0176 0.0559
Schistosoma mansoni ryanodine receptor related 0.0094 0.0273 0.0273
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0094 0.0273 0.0887
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0223 0.0743 0.0743
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0094 0.0273 0.0273
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0223 0.0743 0.0743
Trypanosoma brucei potassium voltage-gated channel, putative 0.0068 0.0176 0.0559
Onchocerca volvulus 0.0046 0.0094 0.0094
Entamoeba histolytica histone deacetylase, putative 0.0344 0.1185 0.3999
Loa Loa (eye worm) notch protein 0.0037 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0037 0.0063 0.0063
Schistosoma mansoni voltage-gated ion channel 0.0094 0.0273 0.0273
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0094 0.0273 0.0273
Brugia malayi hypothetical protein 0.0529 0.1864 0.1864
Schistosoma mansoni cercarial elastase (S01 family) 0.0223 0.0743 0.0743
Loa Loa (eye worm) hypothetical protein 0.0094 0.0273 0.0273
Loa Loa (eye worm) histone deacetylase 7A 0.0339 0.1168 0.1168
Toxoplasma gondii calcium binding egf domain-containing protein 0.0052 0.0116 0.0391
Loa Loa (eye worm) hypothetical protein 0.0046 0.0094 0.0094
Echinococcus multilocularis slit 2 protein 0.0037 0.0063 0.0063
Schistosoma mansoni hypothetical protein 0.0037 0.0063 0.0063
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0092 0.0266 0.0266
Trichomonas vaginalis conserved hypothetical protein 0.0073 0.0194 0.0618
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0223 0.0743 0.0743
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0026 0.0022 0.0022
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.0073 0.0194 0.0618
Brugia malayi PAN domain containing protein 0.0046 0.0094 0.0094
Schistosoma mansoni voltage-gated potassium channel 0.1591 0.5756 0.5756
Schistosoma mansoni hypothetical protein 0.075 0.2675 0.2675
Echinococcus multilocularis notch 0.0037 0.0063 0.0063
Brugia malayi PAN domain containing protein 0.0046 0.0094 0.0094
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0023 0.0012 0.0037
Onchocerca volvulus 0.1356 0.4894 0.4894
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.006 0.0146 0.0146
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0162 0.0522 0.0522
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0162 0.0522 0.0522
Brugia malayi bHLH-PAS transcription factor 0.003 0.0037 0.0037
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0068 0.0176 0.0176
Plasmodium vivax histone deacetylase, putative 0.0339 0.1168 0.3903
Plasmodium falciparum ubiquitin-conjugating enzyme E2 N, putative 0.0058 0.0141 0.0404
Giardia lamblia Alanyl dipeptidyl peptidase 0.0073 0.0194 0.0546
Echinococcus granulosus tyrosine protein kinase Src42A 0.0035 0.0054 0.0054
Echinococcus granulosus peptidase s8 s53 subtilisin kexin sedolisin 0.0081 0.0225 0.0225
Echinococcus granulosus transient receptor potential cation channel 0.0094 0.0273 0.0273
Loa Loa (eye worm) calcium channel 0.0094 0.0273 0.0273
Loa Loa (eye worm) TK/ABL protein kinase 0.0092 0.0266 0.0266
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0094 0.0273 0.0273
Brugia malayi prolyl oligopeptidase family protein 0.0807 0.2884 0.2884
Schistosoma mansoni voltage-gated potassium channel 0.0162 0.0522 0.0522
Loa Loa (eye worm) hypothetical protein 0.0406 0.1413 0.1413
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0094 0.0273 0.0273
Brugia malayi Protein kinase domain containing protein 0.0752 0.2681 0.2681
Echinococcus multilocularis transfer RNA-Gly 0.0162 0.0522 0.0522
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0362 0.1252 0.4213
Loa Loa (eye worm) integrin beta-2 0.1428 0.5159 0.5159
Echinococcus granulosus tyrosine protein kinase Fyn 0.005 0.0109 0.0109
Trypanosoma brucei btb/poz domain containing protein, putative 0.0068 0.0176 0.0559
Trypanosoma brucei histone deacetylase 3 0.0339 0.1168 0.3926
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.1356 0.4894 0.4894
Loa Loa (eye worm) TK protein kinase 0.0021 0.0005 0.0005
Echinococcus multilocularis voltage dependent calcium channel 0.0094 0.0273 0.0273
Brugia malayi K+ channel tetramerisation domain containing protein 0.0068 0.0176 0.0176
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0094 0.0273 0.0887
Trypanosoma brucei oligopeptidase b 0.0073 0.0194 0.0618
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0094 0.0273 0.0273
Echinococcus multilocularis geminin 0.0136 0.0426 0.0426
Brugia malayi EGF-like domain containing protein 0.0029 0.0034 0.0034
Trypanosoma brucei btb/poz domain containing protein, putative 0.0068 0.0176 0.0559
Schistosoma mansoni notch 0.0037 0.0063 0.0063
Onchocerca volvulus 0.0046 0.0094 0.0094
Toxoplasma gondii histone deacetylase HDAC2 0.0344 0.1185 0.4008
Onchocerca volvulus 0.0068 0.0176 0.0176
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.275 1 1
Brugia malayi Delta serrate ligand family protein 0.0037 0.0063 0.0063
Echinococcus granulosus Mastin 0.0223 0.0743 0.0743
Onchocerca volvulus 0.0032 0.0044 0.0044
Onchocerca volvulus 0.275 1 1
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0094 0.0273 0.0273
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0094 0.0273 0.0273
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.0052 0.0116 0.0116
Plasmodium vivax RNA helicase-1, putative 0.0827 0.2956 1
Leishmania major hypothetical protein, conserved 0.0094 0.0273 0.0887
Onchocerca volvulus 0.0046 0.0094 0.0094
Schistosoma mansoni transient receptor potential channel 0.0094 0.0273 0.0273
Echinococcus multilocularis neuropeptide receptor 0.0032 0.0043 0.0043
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0028 0.0031 0.0031
Echinococcus granulosus tyrosine protein kinase Fyn 0.005 0.0109 0.0109
Loa Loa (eye worm) hypothetical protein 0.0094 0.0273 0.0273
Loa Loa (eye worm) prolyl oligopeptidase 0.0807 0.2884 0.2884
Brugia malayi ion channel NompC 0.0094 0.0273 0.0273
Echinococcus multilocularis histone deacetylase 3 0.0344 0.1185 0.1185
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0094 0.0273 0.0887
Loa Loa (eye worm) hypothetical protein 0.0068 0.0176 0.0176
Echinococcus multilocularis transient receptor potential cation channel 0.0094 0.0273 0.0273
Echinococcus granulosus protein jagged 1 0.0037 0.0063 0.0063
Brugia malayi Tyrosine-protein kinase abl-1 0.0059 0.0143 0.0143
Echinococcus multilocularis two pore calcium channel protein 2 0.0094 0.0273 0.0273
Plasmodium falciparum histone deacetylase 2 0.0339 0.1168 0.3903
Toxoplasma gondii prolyl endopeptidase 0.0073 0.0194 0.0653
Plasmodium falciparum kelch protein K13 0.0068 0.0176 0.0524
Brugia malayi Variant SH3 domain containing protein 0.0028 0.0031 0.0031
Echinococcus multilocularis tyrosine protein kinase Srms 0.0036 0.006 0.006
Leishmania major eukaryotic initiation factor 4a, putative 0.0827 0.2956 1
Trypanosoma brucei histone deacetylase 1 0.0344 0.1185 0.3986
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0807 0.2884 0.2884
Loa Loa (eye worm) hypoxia-induced factor 1 0.0126 0.0388 0.0388
Mycobacterium tuberculosis Probable peptidase 0.0073 0.0194 0.0646
Loa Loa (eye worm) hypothetical protein 0.0037 0.0063 0.0063
Trypanosoma brucei histone deacetylase, putative 0.0339 0.1168 0.3926
Trypanosoma brucei prolyl endopeptidase 0.0073 0.0194 0.0618
Loa Loa (eye worm) hypothetical protein 0.0094 0.0273 0.0273
Loa Loa (eye worm) hypothetical protein 0.0073 0.0194 0.0194
Trypanosoma cruzi histone deacetylase, putative 0.0339 0.1168 0.3926
Loa Loa (eye worm) hypothetical protein 0.0037 0.0063 0.0063
Echinococcus granulosus hyperpolarization activated cyclic 0.0094 0.0273 0.0273
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0094 0.0273 0.0887
Echinococcus granulosus tyrosine protein kinase Src42A 0.005 0.0109 0.0109
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0094 0.0273 0.0273
Trypanosoma brucei potassium voltage-gated channel, putative 0.0068 0.0176 0.0559
Schistosoma mansoni voltage-gated potassium channel 0.0094 0.0273 0.0273
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0094 0.0273 0.0273
Onchocerca volvulus 0.0045 0.0091 0.0091
Toxoplasma gondii calcium binding egf domain-containing protein 0.0052 0.0116 0.0391
Echinococcus granulosus glycoprotein Antigen 5 0.0223 0.0743 0.0743
Loa Loa (eye worm) TK protein kinase 0.0036 0.006 0.006
Toxoplasma gondii hypothetical protein 0.0094 0.0273 0.0921
Loa Loa (eye worm) hypothetical protein 0.0073 0.0194 0.0194
Toxoplasma gondii microneme protein MIC4 0.0046 0.0094 0.0317
Brugia malayi Integrin alpha pat-2 precursor 0.0735 0.262 0.262
Schistosoma mansoni voltage-gated potassium channel 0.0094 0.0273 0.0273
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.275 1 1
Schistosoma mansoni histone deacetylase hda2 0.0183 0.0597 0.0597
Echinococcus granulosus fibrillin 2 0.0029 0.0034 0.0034
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.0194 0.0618
Brugia malayi PAN domain containing protein 0.0046 0.0094 0.0094
Echinococcus granulosus inositol monophosphatase 1 0.0023 0.0012 0.0012
Toxoplasma gondii PAN/Apple domain-containing protein 0.0046 0.0094 0.0317
Schistosoma mansoni notch 0.0037 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0037 0.0063 0.0063
Echinococcus granulosus single minded 2 0.003 0.0037 0.0037
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0073 0.0194 0.0194
Echinococcus multilocularis NCK adaptor protein 0.0028 0.0031 0.0031
Schistosoma mansoni histone deacetylase 0.0344 0.1185 0.1185
Loa Loa (eye worm) hypothetical protein 0.0057 0.0137 0.0137
Echinococcus granulosus potassium voltage gated channel protein 0.1591 0.5756 0.5756
Schistosoma mansoni cathepsin D (A01 family) 0.0077 0.0208 0.0208
Echinococcus granulosus neural cadherin 0.0037 0.0063 0.0063
Loa Loa (eye worm) DOMON domain-containing protein 0.0045 0.0091 0.0091
Schistosoma mansoni bhlhzip transcription factor bigmax 0.0252 0.0849 0.0849
Echinococcus granulosus prolyl endopeptidase 0.0073 0.0194 0.0194
Trypanosoma brucei histone deacetylase 4 0.0339 0.1168 0.3926
Echinococcus multilocularis integrin alpha ps 0.0158 0.0506 0.0506
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0252 0.0849 0.0849
Echinococcus multilocularis transmembrane protease serine 3 0.0223 0.0743 0.0743
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0058 0.0141 0.0439
Mycobacterium ulcerans hypothetical protein 0.0223 0.0743 1
Echinococcus granulosus transient receptor potential cation channel 0.0094 0.0273 0.0273
Schistosoma mansoni histone deacetylase hda2 0.0356 0.1229 0.1229
Toxoplasma gondii PAN domain-containing protein 0.0046 0.0094 0.0317
Echinococcus granulosus protein jagged 2 0.0037 0.0063 0.0063
Loa Loa (eye worm) histone deacetylase 3 0.0344 0.1185 0.1185
Brugia malayi hypothetical protein 0.0136 0.0426 0.0426
Schistosoma mansoni notch 0.0037 0.0063 0.0063
Toxoplasma gondii ubiquitin-conjugating enzyme subfamily protein 0.0058 0.0141 0.0475
Toxoplasma gondii PAN domain-containing protein 0.0046 0.0094 0.0317
Trypanosoma cruzi oligopeptidase b 0.0073 0.0194 0.0618
Echinococcus multilocularis BTB:POZ domain containing protein KCTD16 0.0068 0.0176 0.0176
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0362 0.1252 0.4213
Loa Loa (eye worm) hypothetical protein 0.006 0.0146 0.0146
Plasmodium vivax histone deacetylase, putative 0.0183 0.0597 0.1957
Echinococcus granulosus sodium channel protein 0.061 0.2163 0.2163
Loa Loa (eye worm) histone deacetylase 0.0339 0.1168 0.1168
Schistosoma mansoni notch 0.0037 0.0063 0.0063
Loa Loa (eye worm) PAN domain-containing protein 0.0046 0.0094 0.0094
Echinococcus multilocularis transient receptor potential cation channel 0.0094 0.0273 0.0273
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0036 0.006 0.006
Echinococcus multilocularis neurogenic locus notch protein 4 0.0037 0.0063 0.0063
Plasmodium vivax cysteine repeat modular protein 1, putative 0.075 0.2675 0.9042
Schistosoma mansoni hypothetical protein 0.275 1 1
Echinococcus multilocularis potassium large conductance calcium activated 0.0094 0.0273 0.0273
Loa Loa (eye worm) hypothetical protein 0.0172 0.0556 0.0556
Brugia malayi Cadherin domain containing protein 0.0037 0.0063 0.0063
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.061 0.2163 0.2163
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.137 0.4944 0.4944
Brugia malayi EGF-like domain containing protein 0.0029 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.075 0.2675 0.2675
Loa Loa (eye worm) hypothetical protein 0.0156 0.0498 0.0498
Trichomonas vaginalis histone deacetylase, putative 0.0344 0.1185 0.3986
Onchocerca volvulus 0.0223 0.0743 0.0743
Loa Loa (eye worm) hypothetical protein 0.0094 0.0273 0.0273
Echinococcus granulosus potassium voltage gated channel protein 0.0094 0.0273 0.0273
Onchocerca volvulus 0.0045 0.0091 0.0091
Echinococcus multilocularis sodium channel protein 0.061 0.2163 0.2163
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0827 0.2956 0.2956
Brugia malayi Calcium binding EGF domain containing protein 0.0043 0.0084 0.0084
Echinococcus granulosus tyrosine protein kinase Src64B 0.005 0.0109 0.0109
Plasmodium falciparum histone deacetylase, putative 0.0339 0.1168 0.3903
Loa Loa (eye worm) hypothetical protein 0.0577 0.2042 0.2042
Echinococcus multilocularis integrin alpha ps 0.033 0.1135 0.1135
Echinococcus multilocularis potassium voltage gated channel protein 0.0094 0.0273 0.0273
Plasmodium falciparum histone deacetylase 1 0.0344 0.1185 0.3964
Echinococcus granulosus tyrosine protein kinase HCK 0.0021 0.0005 0.0005
Toxoplasma gondii PAN domain-containing protein 0.021 0.0697 0.2355
Echinococcus granulosus slit 2 protein 0.0037 0.0063 0.0063
Echinococcus granulosus integrin alpha ps 0.0158 0.0506 0.0506
Onchocerca volvulus 0.0094 0.0273 0.0273
Loa Loa (eye worm) hypothetical protein 0.0029 0.0034 0.0034
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0057 0.0137 0.0137
Echinococcus multilocularis apoptotic protease activating factor 1 0.0529 0.1864 0.1864
Loa Loa (eye worm) hypothetical protein 0.0031 0.004 0.004
Echinococcus granulosus baculoviral IAP repeat containing protein 0.275 1 1
Echinococcus granulosus potassium voltage gated channel subfamily A 0.1591 0.5756 0.5756
Echinococcus multilocularis integrin alpha 3 0.0564 0.1992 0.1992
Brugia malayi Kringle domain containing protein 0.075 0.2675 0.2675
Mycobacterium ulcerans putative regulatory protein 0.003 0.0037 0.0353
Trypanosoma brucei BTB/POZ domain/Regulator of chromosome condensation (RCC1) repeat, putative 0.0068 0.0176 0.0559
Trypanosoma cruzi histone deacetylase, putative 0.0339 0.1168 0.3926
Brugia malayi Histone deacetylase 1 0.0344 0.1185 0.1185
Trypanosoma cruzi btb/poz domain containing protein, putative 0.0068 0.0176 0.0559
Schistosoma mansoni tyrosine kinase 0.005 0.0109 0.0109
Onchocerca volvulus 0.0223 0.0743 0.0743
Echinococcus granulosus eukaryotic initiation factor 4A 0.0827 0.2956 0.2956
Schistosoma mansoni voltage-gated potassium channel 0.0162 0.0522 0.0522
Schistosoma mansoni hypothetical protein 0.0223 0.0743 0.0743
Echinococcus granulosus max protein X 0.0252 0.0849 0.0849
Echinococcus granulosus potassium voltage gated channel protein 0.0162 0.0522 0.0522
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0094 0.0273 0.0273
Echinococcus granulosus fibropellin Ia 0.0037 0.0063 0.0063
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0362 0.1252 0.4213
Echinococcus multilocularis eukaryotic initiation factor 4A 0.0827 0.2956 0.2956
Toxoplasma gondii histone deacetylase HDAC3 0.0344 0.1185 0.4008
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0094 0.0273 0.0273
Echinococcus granulosus potassium voltage gated channel protein 0.0094 0.0273 0.0273
Brugia malayi Histone deacetylase family protein 0.0339 0.1168 0.1168
Loa Loa (eye worm) hypothetical protein 0.0223 0.0743 0.0743
Echinococcus granulosus c src tyrosine kinase 0.003 0.0037 0.0037
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0026 0.0022 0.0037
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0094 0.0273 0.0273
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0094 0.0273 0.0273
Echinococcus granulosus histone deacetylase 6 0.0356 0.1229 0.1229
Echinococcus granulosus tm gpcr rhodopsin 0.0311 0.1065 0.1065
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0073 0.0194 0.0639
Toxoplasma gondii eukaryotic initiation factor-4A, putative 0.0827 0.2956 1
Brugia malayi EGF-like domain containing protein 0.0037 0.0063 0.0063
Trypanosoma cruzi hypothetical protein, conserved 0.075 0.2675 0.9045
Schistosoma mansoni hypothetical protein 0.0151 0.0479 0.0479
Echinococcus granulosus histone deacetylase 6 0.0339 0.1168 0.1168
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0807 0.2884 0.2884
Schistosoma mansoni cell polarity protein 0.0037 0.0063 0.0063
Schistosoma mansoni notch 0.0037 0.0063 0.0063
Schistosoma mansoni growth factor receptor-bound protein 0.0216 0.0717 0.0717
Toxoplasma gondii PAN domain-containing protein 0.0046 0.0094 0.0317
Echinococcus multilocularis enteropeptidase 0.0223 0.0743 0.0743
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0094 0.0273 0.0273
Echinococcus multilocularis fibropellin Ia 0.0037 0.0063 0.0063
Brugia malayi EGF-like domain containing protein 0.0029 0.0034 0.0034
Echinococcus multilocularis tyrosine protein kinase Fyn 0.005 0.0109 0.0109
Echinococcus multilocularis histone deacetylase 1 0.0344 0.1185 0.1185
Onchocerca volvulus 0.0068 0.0176 0.0176
Onchocerca volvulus 0.0223 0.0743 0.0743
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0162 0.0522 0.0522
Loa Loa (eye worm) PAN domain-containing protein 0.0046 0.0094 0.0094
Loa Loa (eye worm) hypothetical protein 0.0223 0.0743 0.0743
Schistosoma mansoni voltage-dependent calcium channel 0.0094 0.0273 0.0273
Brugia malayi Trypsin family protein 0.0223 0.0743 0.0743
Echinococcus granulosus inhibitor of apoptosis protein 0.275 1 1
Schistosoma mansoni hypothetical protein 0.0223 0.0743 0.0743
Brugia malayi Calcium binding EGF domain containing protein 0.0037 0.0063 0.0063
Schistosoma mansoni hypothetical protein 0.0037 0.0063 0.0063
Echinococcus granulosus histone deacetylase 8 0.0183 0.0597 0.0597
Leishmania major oligopeptidase b 0.0073 0.0194 0.0618
Loa Loa (eye worm) PAN domain-containing protein 0.0046 0.0094 0.0094
Echinococcus multilocularis ubiquitin conjugating enzyme E2 N 0.0058 0.0141 0.0141
Loa Loa (eye worm) hypothetical protein 0.1356 0.4894 0.4894
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0058 0.0141 0.0439
Brugia malayi hypoxia-induced factor 1 0.0126 0.0388 0.0388
Brugia malayi notch-like transmembrane receptor 0.0037 0.0063 0.0063
Giardia lamblia Alanyl dipeptidyl peptidase 0.0073 0.0194 0.0546
Onchocerca volvulus Slit protein homolog 0.0037 0.0063 0.0063
Loa Loa (eye worm) voltage-gated potassium channel 0.0094 0.0273 0.0273
Leishmania major hypothetical protein, conserved 0.0068 0.0176 0.0559
Echinococcus multilocularis inhibitor of apoptosis protein 0.275 1 1
Schistosoma mansoni laminin gamma-3 chain 0.0037 0.0063 0.0063
Echinococcus multilocularis tissue type plasminogen activator 0.075 0.2675 0.2675
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0094 0.0273 0.0273
Schistosoma mansoni bhlhzip transcription factor bigmax 0.0252 0.0849 0.0849
Loa Loa (eye worm) hypothetical protein 0.0094 0.0273 0.0273
Echinococcus granulosus laminin 0.0052 0.0116 0.0116
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0827 0.2956 1
Echinococcus multilocularis calcium activated potassium channel 0.0094 0.0273 0.0273
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0023 0.0012 0.5
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0035 0.0054 0.0054
Trypanosoma cruzi prolyl endopeptidase 0.0073 0.0194 0.0618
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0068 0.0176 0.0524
Echinococcus multilocularis histone deacetylase 6 0.0356 0.1229 0.1229
Echinococcus multilocularis voltage gated potassium channel 0.0162 0.0522 0.0522
Brugia malayi EGF-like domain containing protein 0.0037 0.0063 0.0063
Brugia malayi EGF-like domain containing protein 0.0029 0.0034 0.0034
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0216 0.0717 0.0717
Loa Loa (eye worm) K+ channel tetramerisation domain-containing protein 0.0068 0.0176 0.0176
Schistosoma mansoni voltage-gated potassium channel 0.0094 0.0273 0.0273
Brugia malayi Trypsin family protein 0.1356 0.4894 0.4894
Loa Loa (eye worm) hypothetical protein 0.0094 0.0273 0.0273
Leishmania major histone deacetylase, putative 0.0344 0.1185 0.3986
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0094 0.0273 0.0887
Brugia malayi Trypsin family protein 0.0223 0.0743 0.0743
Loa Loa (eye worm) hypothetical protein 0.0045 0.0091 0.0091
Echinococcus granulosus neurogenic locus notch protein 4 0.0037 0.0063 0.0063
Schistosoma mansoni hypothetical protein 0.0136 0.0426 0.0426
Trichomonas vaginalis histone deacetylase, putative 0.0344 0.1185 0.3986
Schistosoma mansoni nck2/grb4 0.0028 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0529 0.1864 0.1864
Echinococcus multilocularis neurogenic locus protein delta 0.0037 0.0063 0.0063
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0362 0.1252 0.1252
Onchocerca volvulus 0.0529 0.1864 0.1864
Loa Loa (eye worm) integrin alpha pat-2 0.0974 0.3495 0.3495
Loa Loa (eye worm) hypothetical protein 0.0094 0.0273 0.0273
Echinococcus granulosus transient receptor potential cation channel 0.0094 0.0273 0.0273
Loa Loa (eye worm) hypothetical protein 0.0026 0.0022 0.0022
Plasmodium falciparum eukaryotic initiation factor 4A 0.0827 0.2956 1
Loa Loa (eye worm) STAT protein 0.0072 0.0192 0.0192
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.006 0.0146 0.0146
Echinococcus multilocularis Mastin 0.0223 0.0743 0.0743
Echinococcus multilocularis sodium leak channel non selective protein 0.0094 0.0273 0.0273
Echinococcus granulosus voltage dependent calcium channel 0.0094 0.0273 0.0273
Brugia malayi PAN domain containing protein 0.0046 0.0094 0.0094
Loa Loa (eye worm) hypothetical protein 0.0094 0.0273 0.0273
Brugia malayi Transient-receptor-potential like protein 0.0094 0.0273 0.0273
Echinococcus multilocularis tyrosine protein kinase Abl 0.0059 0.0143 0.0143
Echinococcus granulosus NCK adaptor protein 0.0028 0.0031 0.0031
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.0789 0.2816 0.2816
Loa Loa (eye worm) hypothetical protein 0.0094 0.0273 0.0273
Onchocerca volvulus 0.0068 0.0176 0.0176
Brugia malayi EGF-like domain containing protein 0.0037 0.0063 0.0063
Onchocerca volvulus 0.0068 0.0176 0.0176
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0073 0.0194 0.0618
Loa Loa (eye worm) hypothetical protein 0.0037 0.0063 0.0063
Echinococcus multilocularis tyrosine protein kinase HCK 0.0021 0.0005 0.0005
Entamoeba histolytica hypothetical protein, conserved 0.0073 0.0194 0.0639
Echinococcus multilocularis tyrosine protein kinase Src64B 0.005 0.0109 0.0109
Brugia malayi prolyl oligopeptidase family protein 0.0073 0.0194 0.0194
Toxoplasma gondii hypothetical protein 0.0029 0.0034 0.0113
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0073 0.0194 0.0618
Onchocerca volvulus 0.0046 0.0094 0.0094
Loa Loa (eye worm) hypothetical protein 0.0046 0.0094 0.0094
Entamoeba histolytica prolyl oligopeptidase family protein 0.0073 0.0194 0.0639
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0073 0.0194 0.0646
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0073 0.0194 0.0618
Schistosoma mansoni cercarial elastase (S01 family) 0.0223 0.0743 0.0743
Plasmodium falciparum peptidase, putative 0.0073 0.0194 0.0584
Loa Loa (eye worm) hypothetical protein 0.0037 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0031 0.004 0.004
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0162 0.0522 0.0522
Echinococcus multilocularis c src tyrosine kinase 0.003 0.0037 0.0037
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0223 0.0743 0.0743
Loa Loa (eye worm) Kv4.2 voltage-gated potassium channel 0.0068 0.0176 0.0176
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0028 0.0031 0.0031
Loa Loa (eye worm) K+ channel tetramerisation domain-containing protein 0.0068 0.0176 0.0176
Loa Loa (eye worm) hypothetical protein 0.0094 0.0273 0.0273
Echinococcus granulosus neurogenic locus notch protein 0.0037 0.0063 0.0063
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0026 0.0022 0.0022
Brugia malayi Cyclic-nucleotide gated cation channel 0.0094 0.0273 0.0273
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0162 0.0522 0.0522
Echinococcus multilocularis shaker cognate 0.0162 0.0522 0.0522
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0094 0.0273 0.0273
Brugia malayi PAN domain containing protein 0.0046 0.0094 0.0094
Schistosoma mansoni slit 0.0037 0.0063 0.0063
Echinococcus multilocularis voltage gated potassium channel 0.0094 0.0273 0.0273
Brugia malayi SRC-1 0.005 0.0109 0.0109
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0094 0.0273 0.0273
Trypanosoma cruzi histone deacetylase, putative 0.0183 0.0597 0.1987
Echinococcus multilocularis transient receptor potential cation channel 0.0094 0.0273 0.0273
Loa Loa (eye worm) hypothetical protein 0.0037 0.0063 0.0063
Echinococcus granulosus Dipeptidyl peptidase 9 0.0362 0.1252 0.1252
Schistosoma mansoni voltage-gated potassium channel 0.1591 0.5756 0.5756
Loa Loa (eye worm) hypothetical protein 0.0827 0.2956 0.2956
Loa Loa (eye worm) hypothetical protein 0.0183 0.0597 0.0597
Brugia malayi prolyl oligopeptidase family protein 0.0073 0.0194 0.0194
Echinococcus multilocularis potassium voltage gated channel protein 0.1591 0.5756 0.5756
Echinococcus multilocularis transient receptor potential gamma protein 0.0094 0.0273 0.0273
Echinococcus multilocularis neurogenic locus notch protein 0.0037 0.0063 0.0063
Brugia malayi PAN domain containing protein 0.0046 0.0094 0.0094
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0073 0.0194 0.0618
Echinococcus multilocularis protein jagged 2 0.0037 0.0063 0.0063
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0362 0.1252 0.1252
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0026 0.0022 0.0074
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0344 0.1185 0.3986
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0094 0.0273 0.0273
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0094 0.0273 0.0273
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0094 0.0273 0.0273
Schistosoma mansoni edp1-related 0.0068 0.0176 0.0176
Echinococcus granulosus potassium voltage gated channel protein 0.0162 0.0522 0.0522
Toxoplasma gondii hypothetical protein 0.0046 0.0094 0.0317
Schistosoma mansoni voltage-gated potassium channel 0.0162 0.0522 0.0522
Loa Loa (eye worm) inositol-1 0.0023 0.0012 0.0012
Toxoplasma gondii histone deacetylase HDAC4 0.0183 0.0597 0.2016
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0094 0.0273 0.0273
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0057 0.0137 0.0137
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0827 0.2956 1
Schistosoma mansoni inhibitor of apoptosis protein 0.275 1 1
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0066 0.0168 0.0168
Plasmodium falciparum cysteine repeat modular protein 1 0.075 0.2675 0.9042
Schistosoma mansoni 60S ribosomal protein L21 0.0094 0.0273 0.0273
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0094 0.0273 0.0273
Brugia malayi cation channel family protein 0.0094 0.0273 0.0273
Brugia malayi Fibulin-1 precursor 0.0052 0.0116 0.0116
Toxoplasma gondii subtilisin SUB12 0.0052 0.0119 0.04
Loa Loa (eye worm) hypothetical protein 0.0037 0.0063 0.0063
Onchocerca volvulus 0.0037 0.0063 0.0063
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0311 0.1065 0.1065
Echinococcus granulosus potassium large conductance calcium activated 0.0094 0.0273 0.0273
Schistosoma mansoni cercarial elastase (S01 family) 0.0223 0.0743 0.0743
Loa Loa (eye worm) hypothetical protein 0.1591 0.5756 0.5756
Echinococcus granulosus enteropeptidase 0.0223 0.0743 0.0743
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0094 0.0273 0.0273
Trypanosoma brucei prolyl oligopeptidase, putative 0.0073 0.0194 0.0618
Schistosoma mansoni voltage-gated potassium channel 0.0162 0.0522 0.0522
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.005 0.0109 0.0109
Loa Loa (eye worm) hypothetical protein 0.0126 0.0389 0.0389
Schistosoma mansoni voltage-gated potassium channel 0.0094 0.0273 0.0273
Mycobacterium tuberculosis Probable cold-shock DeaD-box protein A homolog DeaD (ATP-dependent RNA helicase dead homolog) 0.0827 0.2956 1
Loa Loa (eye worm) hypothetical protein 0.0344 0.1185 0.1185
Brugia malayi prolyl oligopeptidase family protein 0.0073 0.0194 0.0194
Schistosoma mansoni hypothetical protein 0.0037 0.0063 0.0063
Trypanosoma brucei histone deacetylase 2 0.0183 0.0597 0.1987
Echinococcus granulosus histone deacetylase 0.0339 0.1168 0.1168
Echinococcus granulosus eukaryotic initiation factor 4A III 0.0827 0.2956 0.2956
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0094 0.0273 0.0273
Echinococcus granulosus tyrosine protein kinase Btk29A 0.003 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.0052 0.0116 0.0116
Brugia malayi hypothetical protein 0.0094 0.0273 0.0273
Schistosoma mansoni cercarial elastase (S01 family) 0.0223 0.0743 0.0743
Brugia malayi Calcium binding EGF domain containing protein 0.0052 0.0116 0.0116
Echinococcus granulosus tissue type plasminogen activator 0.075 0.2675 0.2675
Echinococcus multilocularis short transient receptor potential channel 6 0.0094 0.0273 0.0273
Echinococcus granulosus ubiquitin conjugating enzyme E2 N 0.0058 0.0141 0.0141
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0022 0.0009 0.0009
Schistosoma mansoni inositol monophosphatase 0.0023 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0173 0.056 0.056
Schistosoma mansoni histone deacetylase 1 2 3 0.0183 0.0597 0.0597
Onchocerca volvulus 0.0046 0.0094 0.0094
Leishmania major hypothetical protein, conserved 0.0068 0.0176 0.0559
Toxoplasma gondii histone deacetylase HDAC1 0.0339 0.1168 0.3948
Loa Loa (eye worm) hypothetical protein 0.0037 0.0063 0.0063
Schistosoma mansoni hypothetical protein 0.0037 0.0063 0.0063
Schistosoma mansoni voltage-gated potassium channel 0.0094 0.0273 0.0273
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0058 0.0141 0.0141
Brugia malayi PAN domain containing protein 0.0046 0.0094 0.0094
Echinococcus multilocularis G protein coupled receptor 139 0.0032 0.0043 0.0043
Schistosoma mansoni integrin alpha 0.0735 0.262 0.262
Brugia malayi Sex muscle abnormal protein 5 0.0216 0.0717 0.0717
Echinococcus granulosus histone deacetylase 6 0.0339 0.1168 0.1168
Echinococcus granulosus tyrosine protein kinase ABL1 0.0092 0.0266 0.0266
Brugia malayi EGF-like domain containing protein 0.0037 0.0063 0.0063
Onchocerca volvulus 0.0046 0.0094 0.0094
Loa Loa (eye worm) voltage-gated potassium channel 0.0162 0.0522 0.0522
Brugia malayi Subtilase family protein 0.0217 0.0724 0.0724
Echinococcus multilocularis protein jagged 1 0.0037 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.1356 0.4894 0.4894
Loa Loa (eye worm) hypothetical protein 0.0037 0.0063 0.0063
Schistosoma mansoni hypothetical protein 0.0037 0.0063 0.0063
Schistosoma mansoni hypothetical protein 0.0094 0.0273 0.0273
Loa Loa (eye worm) TK/ROR protein kinase 0.0752 0.2681 0.2681
Schistosoma mansoni tyrosine kinase 0.003 0.0037 0.0037
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0026 0.0022 0.0022
Leishmania major histone deacetylase, putative 0.0344 0.1185 0.3986
Schistosoma mansoni voltage-gated potassium channel 0.0094 0.0273 0.0273
Trypanosoma cruzi potassium voltage-gated channel 0.0068 0.0176 0.0559
Echinococcus granulosus growth factor receptor bound protein 2 0.0216 0.0717 0.0717
Toxoplasma gondii aspartyl protease ASP1 0.0026 0.0022 0.0074
Echinococcus granulosus tyrosine protein kinase Lyn 0.005 0.0109 0.0109
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.1591 0.5756 0.5756
Brugia malayi K+ channel tetramerisation domain containing protein 0.0068 0.0176 0.0176
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0073 0.0194 0.0639
Schistosoma mansoni neuropeptide receptor 0.0032 0.0043 0.0043
Trypanosoma cruzi btb/poz domain containing protein, putative 0.0068 0.0176 0.0559
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0362 0.1252 0.4213
Toxoplasma gondii K+ channel tetramerisation domain-containing protein 0.0068 0.0176 0.0594
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0223 0.0743 0.0743
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0094 0.0273 0.0273
Onchocerca volvulus 0.0223 0.0743 0.0743
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0036 0.006 0.006
Brugia malayi histone deacetylase 3 (HD3) 0.0344 0.1185 0.1185
Brugia malayi K+ channel tetramerisation domain containing protein 0.0068 0.0176 0.0176
Brugia malayi protein-tyrosine kinase 0.0036 0.006 0.006
Echinococcus granulosus histone deacetylase 7 0.0339 0.1168 0.1168
Loa Loa (eye worm) hypothetical protein 0.0043 0.0084 0.0084
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0308 0.1057 0.3574
Echinococcus multilocularis histone deacetylase 8 0.0183 0.0597 0.0597
Echinococcus multilocularis hyperpolarization activated cyclic 0.0094 0.0273 0.0273
Brugia malayi ubiquitin conjugating enzyme protein 13 0.0058 0.0141 0.0141
Echinococcus granulosus geminin 0.0136 0.0426 0.0426
Loa Loa (eye worm) hypothetical protein 0.0094 0.0273 0.0273
Loa Loa (eye worm) hypothetical protein 0.0037 0.0063 0.0063
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0094 0.0273 0.0273
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0827 0.2956 0.2956
Loa Loa (eye worm) hypothetical protein 0.0037 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0046 0.0094 0.0094
Plasmodium vivax K+ channel tetramerisation domain containing protein 0.0068 0.0176 0.0524
Echinococcus multilocularis prolyl endopeptidase 0.0073 0.0194 0.0194
Schistosoma mansoni hypothetical protein 0.0136 0.0426 0.0426
Trypanosoma cruzi oligopeptidase b 0.0073 0.0194 0.0618
Loa Loa (eye worm) hypothetical protein 0.0094 0.0273 0.0273
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.003 0.0037 0.0037
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0094 0.0273 0.0273
Loa Loa (eye worm) hypothetical protein 0.0037 0.0063 0.0063
Schistosoma mansoni voltage-gated potassium channel 0.0068 0.0176 0.0176
Loa Loa (eye worm) hypothetical protein 0.0046 0.0094 0.0094
Onchocerca volvulus Deterin homolog 0.275 1 1
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0094 0.0273 0.0273
Trypanosoma cruzi histone deacetylase 1, putative 0.0344 0.1185 0.3986
Echinococcus granulosus transient receptor potential cation channel 0.0094 0.0273 0.0273
Loa Loa (eye worm) hypothetical protein 0.0037 0.0063 0.0063
Brugia malayi Voltage-gated potassium channel, Shal-family (KCND, Kv4-like) alpha-subunit. C. elegans shl-1 ortholog 0.0068 0.0176 0.0176
Loa Loa (eye worm) hypothetical protein 0.0094 0.0273 0.0273
Loa Loa (eye worm) hypothetical protein 0.0158 0.0506 0.0506
Toxoplasma gondii PAN domain-containing protein 0.0046 0.0094 0.0317
Echinococcus granulosus sodium leak channel non selective protein 0.0094 0.0273 0.0273
Loa Loa (eye worm) hypothetical protein 0.0223 0.0743 0.0743
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0094 0.0273 0.0273
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0073 0.0194 0.0618
Brugia malayi STAT protein, DNA binding domain containing protein 0.0072 0.0192 0.0192
Schistosoma mansoni voltage-gated potassium channel 0.0094 0.0273 0.0273
Echinococcus multilocularis fibrillin 2 0.0029 0.0034 0.0034
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0058 0.0141 0.0439
Echinococcus granulosus shaker cognate 0.0162 0.0522 0.0522
Schistosoma mansoni histone deacetylase 4 5 0.0339 0.1168 0.1168
Brugia malayi Cadherin domain containing protein 0.0037 0.0063 0.0063
Toxoplasma gondii 1,3(4)-beta-glucanase 0.0046 0.0094 0.0317
Loa Loa (eye worm) hypothetical protein 0.0037 0.0063 0.0063
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0094 0.0273 0.0273
Loa Loa (eye worm) hypothetical protein 0.0037 0.0063 0.0063
Entamoeba histolytica ubiquitin-conjugating enzyme family protein 0.0058 0.0141 0.0461
Brugia malayi SEA domain containing protein 0.0045 0.0091 0.0091
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0094 0.0273 0.0273
Loa Loa (eye worm) voltage-dependent calcium channel 0.0094 0.0273 0.0273
Echinococcus multilocularis transient receptor potential cation channel 0.0094 0.0273 0.0273
Loa Loa (eye worm) SRC-1 0.005 0.0109 0.0109
Echinococcus granulosus transient receptor potential cation channel 0.0094 0.0273 0.0273
Schistosoma mansoni ubiquitin conjugating enzyme 13 0.0058 0.0141 0.0141
Onchocerca volvulus 0.0046 0.0094 0.0094
Loa Loa (eye worm) hypothetical protein 0.0029 0.0034 0.0034
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0094 0.0273 0.0273
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0026 0.0022 0.0022
Leishmania major ubiquitin-conjugating enzyme e2, putative 0.0058 0.0141 0.0439
Echinococcus multilocularis caspase 2 0.0529 0.1864 0.1864
Schistosoma mansoni adapter molecule crk 0.0028 0.0031 0.0031
Schistosoma mansoni hypothetical protein 0.0529 0.1864 0.1864
Schistosoma mansoni cercarial elastase (S01 family) 0.0223 0.0743 0.0743
Echinococcus multilocularis tyrosine protein kinase Blk 0.0036 0.006 0.006
Brugia malayi EGF-like domain containing protein 0.0037 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0046 0.0094 0.0094
Echinococcus multilocularis laminin 0.0052 0.0116 0.0116
Brugia malayi histone deacetylase 1 (HD1) 0.0344 0.1185 0.1185
Loa Loa (eye worm) hypothetical protein 0.0094 0.0273 0.0273
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0094 0.0273 0.0273
Onchocerca volvulus 0.0045 0.0091 0.0091
Leishmania major hypothetical protein, unknown function 0.0094 0.0273 0.0887
Schistosoma mansoni potassium channel tetramerization domain-containing 0.0068 0.0176 0.0176
Loa Loa (eye worm) hypothetical protein 0.0162 0.0522 0.0522
Echinococcus multilocularis conserved hypothetical protein 0.0094 0.0273 0.0273
Toxoplasma gondii hypothetical protein 0.0073 0.0194 0.0653
Schistosoma mansoni histone deacetylase 4 5 0.0339 0.1168 0.1168
Echinococcus multilocularis BTB:POZ domain containing protein 0.0068 0.0176 0.0176
Echinococcus multilocularis histone deacetylase 7 0.0339 0.1168 0.1168
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0037 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0037 0.0063 0.0063
Brugia malayi PAN domain containing protein 0.0046 0.0094 0.0094
Onchocerca volvulus 0.1133 0.4078 0.4078
Brugia malayi Inositol-1 0.0023 0.0012 0.0012
Echinococcus multilocularis integrin beta 2 0.1054 0.3786 0.3786
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0094 0.0273 0.0273
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0094 0.0273 0.0273
Toxoplasma gondii microneme protein MIC17B 0.0046 0.0094 0.0317
Loa Loa (eye worm) hypothetical protein 0.0046 0.0094 0.0094
Echinococcus multilocularis histone deacetylase 6 0.0339 0.1168 0.1168
Echinococcus multilocularis histone deacetylase 0.0339 0.1168 0.1168
Brugia malayi PAS domain containing protein 0.0041 0.0076 0.0076
Schistosoma mansoni cercarial elastase (S01 family) 0.0223 0.0743 0.0743
Brugia malayi mKIAA0176 protein 0.0068 0.0176 0.0176
Echinococcus granulosus two pore calcium channel protein 2 0.0094 0.0273 0.0273
Trypanosoma brucei btb/poz domain containing protein, putative 0.0068 0.0176 0.0559
Trypanosoma cruzi histone deacetylase, putative 0.0183 0.0597 0.1987
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0344 0.1185 0.3986
Echinococcus granulosus voltage gated potassium channel 0.0094 0.0273 0.0273
Trypanosoma cruzi hypothetical protein, conserved 0.0068 0.0176 0.0559
Echinococcus granulosus integrin alpha ps 0.033 0.1135 0.1135
Toxoplasma gondii transporter, cation channel family protein 0.0094 0.0273 0.0921
Echinococcus granulosus transient receptor potential gamma protein 0.0094 0.0273 0.0273
Echinococcus multilocularis glycoprotein Antigen 5 0.0223 0.0743 0.0743
Brugia malayi cation channel family protein 0.0094 0.0273 0.0273
Brugia malayi hypothetical protein 0.022 0.0732 0.0732
Loa Loa (eye worm) hypothetical protein 0.0068 0.0176 0.0176
Echinococcus multilocularis dnaJ subfamily B 0.0151 0.0479 0.0479
Trypanosoma brucei ubiquitin-protein ligase, putative 0.0058 0.0141 0.0439
Schistosoma mansoni tyrosine kinase 0.0078 0.0211 0.0211
Schistosoma mansoni hypothetical protein 0.0037 0.0063 0.0063
Echinococcus granulosus neuropeptide receptor 0.0032 0.0043 0.0043
Echinococcus granulosus protein jagged 1 0.0037 0.0063 0.0063
Brugia malayi olfactory channel protein osm-9 0.0094 0.0273 0.0273
Trypanosoma cruzi btb/poz domain containing protein, putative 0.0068 0.0176 0.0559
Echinococcus granulosus tyrosine protein kinase Blk 0.0036 0.006 0.006
Echinococcus multilocularis tyrosine protein kinase Fyn 0.005 0.0109 0.0109
Schistosoma mansoni vesicular amine transporter 0.0162 0.0522 0.0522
Onchocerca volvulus Histone deacetylase 10 homolog 0.0183 0.0597 0.0597
Loa Loa (eye worm) hypothetical protein 0.0094 0.0273 0.0273
Schistosoma mansoni two-pore calcium channel 0.0094 0.0273 0.0273
Loa Loa (eye worm) hypothetical protein 0.022 0.0732 0.0732
Echinococcus multilocularis fat cadherin tumor suppressor 0.0037 0.0063 0.0063
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0223 0.0743 0.0743
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0094 0.0273 0.0273
Leishmania major histone deacetylase, putative 0.0339 0.1168 0.3926
Brugia malayi hypothetical protein 0.0236 0.0791 0.0791
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0094 0.0273 0.0273
Echinococcus multilocularis transient receptor potential cation channel 0.0094 0.0273 0.0273
Echinococcus multilocularis growth factor receptor bound protein 2 0.0216 0.0717 0.0717
Echinococcus granulosus two pore calcium channel protein 1 0.0094 0.0273 0.0273
Trypanosoma cruzi potassium voltage-gated channel, putative 0.0068 0.0176 0.0559
Echinococcus multilocularis two pore calcium channel protein 1 0.0094 0.0273 0.0273
Echinococcus granulosus TRP transient receptor potential channel 0.0094 0.0273 0.0273
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0094 0.0273 0.0273
Leishmania major hypothetical protein, conserved 0.075 0.2675 0.9045
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.005 0.0109 0.0109
Toxoplasma gondii microneme protein MIC17A 0.0046 0.0094 0.0317
Brugia malayi Ubiquitin conjugating enzyme protein 13 0.0058 0.0141 0.0141
Schistosoma mansoni septate junction protein 0.0037 0.0063 0.0063
Schistosoma mansoni voltage-gated potassium channel 0.0162 0.0522 0.0522
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0094 0.0273 0.0273
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0827 0.2956 1
Echinococcus multilocularis eukaryotic initiation factor 4A III 0.0827 0.2956 0.2956
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0094 0.0273 0.0273
Trichomonas vaginalis histone deacetylase, putative 0.0344 0.1185 0.3986
Brugia malayi EGF-like domain containing protein 0.0037 0.0063 0.0063
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0344 0.1185 0.3986
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0827 0.2956 1
Onchocerca volvulus 0.0068 0.0176 0.0176
Brugia malayi Integrin alpha cytoplasmic region family protein 0.0397 0.1381 0.1381
Loa Loa (eye worm) hypothetical protein 0.0223 0.0743 0.0743
Trichomonas vaginalis histone deacetylase, putative 0.0344 0.1185 0.3986
Loa Loa (eye worm) PAN domain-containing protein 0.0046 0.0094 0.0094
Echinococcus granulosus hypothetical protein 0.0094 0.0273 0.0273
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0094 0.0273 0.0273
Schistosoma mansoni hypothetical protein 0.0158 0.0506 0.0506
Leishmania major calcium channel protein, putative,ion transporter, putative 0.061 0.2163 0.7306
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0094 0.0273 0.0273
Toxoplasma gondii EGF family domain-containing protein 0.0037 0.0063 0.0212
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0162 0.0522 0.0522
Schistosoma mansoni voltage-gated potassium channel 0.0162 0.0522 0.0522
Loa Loa (eye worm) trypsin family protein 0.0223 0.0743 0.0743
Loa Loa (eye worm) hypothetical protein 0.0029 0.0034 0.0034
Schistosoma mansoni growth factor receptor-bound protein 0.0216 0.0717 0.0717
Trypanosoma cruzi btb/poz domain containing protein, putative 0.0068 0.0176 0.0559
Schistosoma mansoni transient receptor potential channel 4 0.0094 0.0273 0.0273
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0094 0.0273 0.0921
Entamoeba histolytica DEAD/DEAH box helicase, putative 0.0827 0.2956 1
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0094 0.0273 0.0273
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0223 0.0743 0.0743
Brugia malayi Muscle positioning protein 4 0.0082 0.0227 0.0227
Brugia malayi Cell death protein 3 precursor 0.0529 0.1864 0.1864
Schistosoma mansoni integrin alpha-ps 0.033 0.1135 0.1135
Echinococcus granulosus acylamino acid releasing enzyme 0.0073 0.0194 0.0194
Schistosoma mansoni egf-like domain protein 0.0052 0.0116 0.0116
Brugia malayi EGF-like domain containing protein 0.0037 0.0063 0.0063
Onchocerca volvulus 0.0037 0.0063 0.0063
Toxoplasma gondii microneme protein, putative 0.0046 0.0094 0.0317
Loa Loa (eye worm) voltage-gated calcium channel 0.0094 0.0273 0.0273
Loa Loa (eye worm) hypothetical protein 0.0094 0.0273 0.0273
Loa Loa (eye worm) hypothetical protein 0.0052 0.0116 0.0116
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0252 0.0849 0.0849
Echinococcus multilocularis max protein X 0.0252 0.0849 0.0849
Loa Loa (eye worm) hypothetical protein 0.0068 0.0176 0.0176
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.005 0.0109 0.0109
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0094 0.0273 0.0273
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.003 0.0037 0.0037
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.1523 0.5507 0.5507
Echinococcus multilocularis Peptidase S8 S53, subtilisin kexin sedolisin 0.0081 0.0225 0.0225
Echinococcus multilocularis voltage dependent calcium channel 0.0094 0.0273 0.0273
Echinococcus granulosus neurogenic locus protein delta 0.0037 0.0063 0.0063
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0094 0.0273 0.0273
Loa Loa (eye worm) hypothetical protein 0.0094 0.0273 0.0273
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0094 0.0273 0.0273
Entamoeba histolytica prolyl oligopeptidase family protein 0.0073 0.0194 0.0639
Plasmodium vivax hypothetical protein, conserved 0.0073 0.0194 0.0584
Echinococcus multilocularis protein jagged 1 0.0037 0.0063 0.0063
Echinococcus multilocularis protein jagged 2 0.0029 0.0034 0.0034
Echinococcus multilocularis integrin alpha ps 0.033 0.1135 0.1135
Onchocerca volvulus 0.0046 0.0094 0.0094
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0037 0.0063 0.0063
Echinococcus multilocularis neurogenic locus notch protein 0.0037 0.0063 0.0063
Loa Loa (eye worm) potassium channel tetramerisation domain containing 3 0.0068 0.0176 0.0176
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0094 0.0273 0.0273
Echinococcus granulosus ryanodine receptor 44f 0.0094 0.0273 0.0273
Loa Loa (eye worm) hypothetical protein 0.0223 0.0743 0.0743
Toxoplasma gondii hypothetical protein 0.0094 0.0273 0.0921
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0031
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0023 0.0012 0.0022
Trichomonas vaginalis hypothetical protein 0.0029 0.0034 0.0076
Echinococcus granulosus voltage dependent calcium channel 0.0094 0.0273 0.0273
Giardia lamblia Histone deacetylase 0.0344 0.1185 0.394
Toxoplasma gondii kringle domain-containing protein 0.075 0.2675 0.9049
Schistosoma mansoni voltage-gated potassium channel 0.0094 0.0273 0.0273
Schistosoma mansoni tripeptidyl-peptidase II (S08 family) 0.0217 0.0724 0.0724
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0094 0.0273 0.0273
Brugia malayi hypothetical protein 0.0223 0.0743 0.0743
Loa Loa (eye worm) subtilase 0.0217 0.0724 0.0724
Schistosoma mansoni cercarial elastase (S01 family) 0.0223 0.0743 0.0743
Schistosoma mansoni tyrosine kinase 0.005 0.0109 0.0109
Echinococcus granulosus BTB:POZ domain containing protein KCTD16 0.0068 0.0176 0.0176
Loa Loa (eye worm) hypothetical protein 0.0529 0.1864 0.1864
Onchocerca volvulus Putative cubilin 0.0043 0.0084 0.0084
Echinococcus granulosus notch 0.0037 0.0063 0.0063
Trypanosoma cruzi histone deacetylase, putative 0.0339 0.1168 0.3926
Echinococcus granulosus calcium activated potassium channel 0.0094 0.0273 0.0273
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0094 0.0273 0.0273
Brugia malayi Integrin beta pat-3 precursor 0.1428 0.5159 0.5159
Loa Loa (eye worm) hypothetical protein 0.0236 0.0791 0.0791
Schistosoma mansoni calcium-activated potassium channel 0.0094 0.0273 0.0273
Brugia malayi K+ channel tetramerisation domain containing protein 0.0068 0.0176 0.0176
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0073 0.0194 0.0194
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0094 0.0273 0.0273
Toxoplasma gondii transporter, cation channel family protein 0.0094 0.0273 0.0921
Plasmodium vivax ubiquitin-conjugating enzyme E2 N, putative 0.0058 0.0141 0.0404
Schistosoma mansoni cercarial elastase (S01 family) 0.0223 0.0743 0.0743
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0094 0.0273 0.0273
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0058 0.0141 0.0141
Loa Loa (eye worm) hypothetical protein 0.0037 0.0063 0.0063
Echinococcus granulosus tyrosine kinase 0.0036 0.006 0.006
Trichomonas vaginalis teneurin and N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase, putative 0.0029 0.0034 0.0076
Echinococcus granulosus adam 0.0029 0.0034 0.0034
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0362 0.1252 0.4213
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0162 0.0522 0.0522
Echinococcus multilocularis neural cadherin 0.0037 0.0063 0.0063
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0827 0.2956 1
Onchocerca volvulus 0.0046 0.0094 0.0094
Echinococcus multilocularis hyperpolarization activated cyclic 0.0094 0.0273 0.0273
Echinococcus granulosus integrin alpha 3 0.0564 0.1992 0.1992
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0073 0.0194 0.0653
Echinococcus granulosus Tolloid protein 1 0.0057 0.0137 0.0137
Schistosoma mansoni voltage-gated potassium channel 0.0094 0.0273 0.0273
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.005 0.0109 0.0109
Loa Loa (eye worm) histone deacetylase 11 0.0183 0.0597 0.0597
Giardia lamblia High cysteine protein 0.0037 0.0063 0.01
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0162 0.0522 0.0522
Trypanosoma cruzi histone deacetylase 1, putative 0.0344 0.1185 0.3986
Schistosoma mansoni inositol monophosphatase 0.0023 0.0012 0.0012
Onchocerca volvulus 0.0082 0.0227 0.0227
Trypanosoma brucei Eukaryotic initiation factor 4A-1 0.0827 0.2956 1
Leishmania major histone deacetylase, putative 0.0339 0.1168 0.3926
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0223 0.0743 0.0743
Trypanosoma brucei btb/poz domain containing protein, putative 0.0068 0.0176 0.0559
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0225 0.0752 0.0752
Loa Loa (eye worm) hypothetical protein 0.0094 0.0273 0.0273
Trichomonas vaginalis histone deacetylase, putative 0.0344 0.1185 0.3986
Echinococcus multilocularis adam 0.0029 0.0034 0.0034
Echinococcus granulosus histone deacetylase 3 0.0344 0.1185 0.1185
Echinococcus multilocularis acylamino acid releasing enzyme 0.0073 0.0194 0.0194
Onchocerca volvulus 0.0045 0.0091 0.0091
Onchocerca volvulus Arrow homolog 0.006 0.0146 0.0146
Echinococcus granulosus voltage gated hydrogen channel 1 0.0094 0.0273 0.0273
Echinococcus granulosus fibrillin 1 0.0029 0.0034 0.0034
Schistosoma mansoni cercarial elastase (S01 family) 0.0223 0.0743 0.0743
Leishmania major hypothetical protein, conserved 0.0068 0.0176 0.0559
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0073 0.0194 1
Onchocerca volvulus 0.0037 0.0063 0.0063
Brugia malayi prolyl oligopeptidase family protein 0.0362 0.1252 0.1252
Onchocerca volvulus Prolyl endopeptidase homolog 0.0073 0.0194 0.0194
Toxoplasma gondii histone deacetylase HDAC5 0.0183 0.0597 0.2016
Echinococcus granulosus histone deacetylase 1 0.0344 0.1185 0.1185
Brugia malayi Trypsin-like protease protein 5 0.0223 0.0743 0.0743
Echinococcus multilocularis Tolloid protein 1 0.0057 0.0137 0.0137
Onchocerca volvulus 0.0046 0.0094 0.0094
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0094 0.0273 0.0887
Plasmodium vivax histone deacetylase 1, putative 0.0344 0.1185 0.3964
Toxoplasma gondii PAN domain-containing protein 0.021 0.0697 0.2355
Schistosoma mansoni voltage-gated potassium channel 0.0068 0.0176 0.0176
Echinococcus granulosus transmembrane protease serine 3 0.0223 0.0743 0.0743
Schistosoma mansoni cathepsin D (A01 family) 0.0077 0.0208 0.0208
Plasmodium vivax kelch protein K13, putative 0.0068 0.0176 0.0524
Echinococcus granulosus neurogenic locus notch protein 0.0037 0.0063 0.0063
Echinococcus granulosus hyperpolarization activated cyclic 0.0094 0.0273 0.0273
Plasmodium vivax histone deacetylase 2, putative 0.0339 0.1168 0.3903
Schistosoma mansoni hypothetical protein 0.0045 0.0091 0.0091
Brugia malayi Calcium binding EGF domain containing protein 0.0037 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.275 1 1
Schistosoma mansoni voltage-gated potassium channel 0.0094 0.0273 0.0273
Loa Loa (eye worm) ion channel NompC 0.0094 0.0273 0.0273
Brugia malayi Angiotensin-converting enzyme family protein 0.0789 0.2816 0.2816
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0223 0.0743 0.0743
Echinococcus granulosus apoptotic protease activating factor 1 0.0529 0.1864 0.1864
Brugia malayi PAN domain containing protein 0.0046 0.0094 0.0094
Echinococcus multilocularis short transient receptor potential channel 6 0.0094 0.0273 0.0273
Brugia malayi Variant SH3 domain containing protein 0.0028 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0094 0.0273 0.0273
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0094 0.0273 0.0273
Loa Loa (eye worm) Notch2 0.0037 0.0063 0.0063
Toxoplasma gondii transporter, cation channel family protein 0.0094 0.0273 0.0921
Echinococcus multilocularis ryanodine receptor 44f 0.0094 0.0273 0.0273
Echinococcus granulosus short transient receptor potential channel 6 0.0094 0.0273 0.0273
Echinococcus granulosus short transient receptor potential channel 6 0.0094 0.0273 0.0273
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.0194 0.0618
Echinococcus multilocularis fibrillin 1 0.0081 0.0223 0.0223
Brugia malayi GCC2 and GCC3 family protein 0.0037 0.0063 0.0063
Schistosoma mansoni transient receptor potential channel 0.0094 0.0273 0.0273
Schistosoma mansoni voltage-gated cation channel 0.0094 0.0273 0.0273
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0073 0.0194 0.0618
Schistosoma mansoni caspase-7 (C14 family) 0.0529 0.1864 0.1864
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0094 0.0273 0.0273
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0073 0.0194 0.0194
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0094 0.0273 0.0273
Schistosoma mansoni voltage-gated potassium channel 0.0068 0.0176 0.0176
Onchocerca volvulus 0.0029 0.0034 0.0034
Onchocerca volvulus Cell death protein 3 homolog 0.0529 0.1864 0.1864
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0094 0.0273 0.0273
Schistosoma mansoni cercarial elastase (S01 family) 0.0223 0.0743 0.0743
Echinococcus granulosus protein jagged 2 0.0037 0.0063 0.0063
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0094 0.0273 0.0921
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0223 0.0743 0.0743
Echinococcus granulosus dnaJ subfamily B 0.0151 0.0479 0.0479
Schistosoma mansoni integrin alpha-ps 0.0172 0.0556 0.0556
Onchocerca volvulus Eukaryotic initiation factor 4A homolog 0.0827 0.2956 0.2956
Echinococcus multilocularis potassium voltage gated channel protein 0.0162 0.0522 0.0522
Leishmania major eukaryotic initiation factor 4a, putative 0.0827 0.2956 1
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0807 0.2884 0.2884
Loa Loa (eye worm) hypothetical protein 0.0037 0.0063 0.0063
Schistosoma mansoni single-minded 0.0041 0.0076 0.0076
Echinococcus multilocularis potassium voltage gated channel protein 0.0162 0.0522 0.0522
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0066 0.0168 0.0168
Schistosoma mansoni integrin beta subunit 0.0834 0.2982 0.2982
Onchocerca volvulus 0.0223 0.0743 0.0743
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.275 1 1
Loa Loa (eye worm) hypothetical protein 0.0094 0.0273 0.0273
Schistosoma mansoni notch 0.0037 0.0063 0.0063
Brugia malayi Kelch motif family protein 0.0225 0.0752 0.0752
Brugia malayi eukaryotic initiation factor 4A 0.0827 0.2956 0.2956
Echinococcus multilocularis tyrosine protein kinase Fyn 0.005 0.0109 0.0109
Treponema pallidum ATP-dependent RNA helicase 0.0827 0.2956 0.5
Trichomonas vaginalis histone deacetylase, putative 0.0344 0.1185 0.3986
Echinococcus multilocularis inositol monophosphatase 1 0.0023 0.0012 0.0012
Brugia malayi PAN domain containing protein 0.0046 0.0094 0.0094
Echinococcus granulosus BTB:POZ domain containing protein 0.0068 0.0176 0.0176
Loa Loa (eye worm) hypothetical protein 0.0397 0.1381 0.1381
Loa Loa (eye worm) hypothetical protein 0.0046 0.0094 0.0094
Echinococcus multilocularis transient receptor potential cation channel 0.0094 0.0273 0.0273
Loa Loa (eye worm) hypothetical protein 0.0029 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0037 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0136 0.0426 0.0426
Loa Loa (eye worm) hypothetical protein 0.0065 0.0166 0.0166
Loa Loa (eye worm) histone deacetylase 1 0.0344 0.1185 0.1185
Schistosoma mansoni transient receptor potential channel 0.0094 0.0273 0.0273
Entamoeba histolytica prolyl oligopeptidase family protein 0.0073 0.0194 0.0639
Schistosoma mansoni histone deacetylase 0.0344 0.1185 0.1185
Toxoplasma gondii microneme protein MIC17C 0.0046 0.0094 0.0317
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.005 0.0109 0.0109
Echinococcus multilocularis tyrosine protein kinase Src42A 0.005 0.0109 0.0109
Leishmania major potassium voltage-gated channel, putative 0.0068 0.0176 0.0559
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0094 0.0273 0.0273
Echinococcus multilocularis histone deacetylase 6 0.0339 0.1168 0.1168
Onchocerca volvulus 0.0046 0.0094 0.0094
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0807 0.2884 0.2884
Echinococcus multilocularis neurogenic locus protein delta 0.0037 0.0063 0.0063
Onchocerca volvulus 0.075 0.2675 0.2675
Echinococcus granulosus delta-like protein 1 0.0037 0.0063 0.0063
Echinococcus granulosus voltage gated potassium channel 0.0162 0.0522 0.0522
Loa Loa (eye worm) hypothetical protein 0.0082 0.0227 0.0227
Loa Loa (eye worm) potassium channel tetramerisation domain containing 5 0.0068 0.0176 0.0176
Schistosoma mansoni tyrosine kinase 0.003 0.0037 0.0037
Brugia malayi Tyrosine-protein kinase abl-1 0.0047 0.0099 0.0099
Echinococcus multilocularis tyrosine protein kinase Fgr 0.005 0.0109 0.0109
Schistosoma mansoni cercarial elastase (S01 family) 0.0223 0.0743 0.0743
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0228 0.0763 0.0763
Echinococcus multilocularis transfer RNA-Lys 0.003 0.0037 0.0037
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0073 0.0194 0.0194
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0073 0.0194 0.0618
Echinococcus granulosus caspase 2 0.0529 0.1864 0.1864
Brugia malayi Trypsin family protein 0.0223 0.0743 0.0743
Onchocerca volvulus Neurogenic locus notch homolog 0.0037 0.0063 0.0063
Loa Loa (eye worm) ryanodine receptor 0.0094 0.0273 0.0273
Echinococcus granulosus tyrosine protein kinase Fyn 0.005 0.0109 0.0109
Echinococcus granulosus transient receptor potential cation channel 0.0094 0.0273 0.0273
Loa Loa (eye worm) hypothetical protein 0.275 1 1
Loa Loa (eye worm) prolyl oligopeptidase 0.0073 0.0194 0.0194
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0094 0.0273 0.0273
Brugia malayi Histone deacetylase family protein 0.0339 0.1168 0.1168
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0162 0.0522 0.0522
Toxoplasma gondii hypothetical protein 0.0046 0.0094 0.0317
Toxoplasma gondii kelch repeat and K+ channel tetramerisation domain containing protein 0.0068 0.0176 0.0594
Loa Loa (eye worm) K+ channel tetramerisation domain-containing protein 0.0068 0.0176 0.0176
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0073 0.0194 0.249

Activities

Activity type Activity value Assay description Source Reference
Activity (functional) Antifungal activity against Candida albicans by microdilution test ChEMBL. 21093111
Activity (functional) Antifungal activity against Cryptococcus neoformans by microdilution test ChEMBL. 21093111

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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