Detailed information for compound 1556886

Basic information

Technical information
  • TDR Targets ID: 1556886
  • Name: 2-methyl-1,10-phenanthroline
  • MW: 194.232 | Formula: C13H10N2
  • H donors: 0 H acceptors: 2 LogP: 2.86 Rotable bonds: 0
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1ccc2c(n1)c1ncccc1cc2
  • InChi: 1S/C13H10N2/c1-9-4-5-11-7-6-10-3-2-8-14-12(10)13(11)15-9/h2-8H,1H3
  • InChiKey: LQZDYPHFVGRHKD-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • ZINC04228177
  • MLS001001117
  • SMR000498798

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens glycoprotein hormones, alpha polypeptide Starlite/ChEMBL No references
Homo sapiens glucagon-like peptide 1 receptor Starlite/ChEMBL No references
Influenza A virus Nonstructural protein 1 Starlite/ChEMBL No references
Homo sapiens geminin, DNA replication inhibitor Starlite/ChEMBL No references
Homo sapiens ataxin 2 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Mycobacterium tuberculosis Hypothetical protein Nonstructural protein 1   230 aa 202 aa 23.8 %
Loa Loa (eye worm) pigment dispersing factor receptor c glucagon-like peptide 1 receptor 463 aa 388 aa 25.8 %
Brugia malayi Hypothetical 65.5 kDa Trp-Asp repeats containing protein F02E8.5 inchromosome X geminin, DNA replication inhibitor 209 aa 176 aa 27.8 %
Toxoplasma gondii intraflagellar transport protein 172, putative glycoprotein hormones, alpha polypeptide 116 aa 94 aa 26.6 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis thyroid hormone receptor alpha 0.0012 0.0099 0.0214
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0036 0.0583 0.1423
Schistosoma mansoni Smad4 0.001 0.005 0.0093
Echinococcus multilocularis two pore calcium channel protein 1 0.0071 0.1289 0.3187
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0071 0.1289 0.3187
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0071 0.1289 1
Echinococcus multilocularis voltage dependent calcium channel 0.0071 0.1289 0.3187
Echinococcus multilocularis dna polymerase eta 0.0023 0.0325 0.0779
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0187 0.0779
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0187 0.0779
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0022 0.0304 0.6138
Loa Loa (eye worm) steroid hormone receptor 0.0012 0.0099 0.0309
Brugia malayi Hsp90 protein 0.0016 0.0178 0.0594
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0023 0.0325 0.1124
Echinococcus granulosus solute carrier family 22 0.0017 0.0187 0.0434
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0041 0.0687 0.5282
Echinococcus multilocularis transient receptor potential cation channel 0.0076 0.1392 0.3446
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.0239 0.0564
Schistosoma mansoni coup transcription factor 0.0012 0.0099 0.0214
Brugia malayi ecdysteroid receptor 0.0012 0.0099 0.0309
Trypanosoma brucei glucose transporter, putative 0.0036 0.0592 0.454
Trypanosoma brucei heat shock protein, putative 0.0039 0.0649 0.4988
Onchocerca volvulus 0.0017 0.0187 0.1361
Trypanosoma cruzi heat shock protein 85, putative 0.0039 0.0649 0.4988
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0031 0.0487 0.1183
Echinococcus multilocularis TGF beta signal transducer SmadC 0.001 0.005 0.0093
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0012 0.0099 0.0309
Echinococcus granulosus sodium leak channel non selective protein 0.0071 0.1289 0.3187
Echinococcus granulosus tar DNA binding protein 0.0076 0.1407 0.3484
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0026 0.0384 0.7838
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0187 0.0779
Echinococcus granulosus mothers against decapentaplegic 5 0.001 0.005 0.0093
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0071 0.1289 0.4602
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0071 0.1289 0.3187
Trichomonas vaginalis conserved hypothetical protein 0.0117 0.2242 1
Trypanosoma brucei DNA polymerase eta, putative 0.0023 0.0325 0.2443
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0019 0.0238 0.0812
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0187 0.0779
Giardia lamblia Prolyl-tRNA synthetase 0.0035 0.0568 0.8746
Loa Loa (eye worm) hypothetical protein 0.0071 0.1289 0.4602
Schistosoma mansoni hypothetical protein 0.0019 0.0238 0.0562
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0325 0.2443
Loa Loa (eye worm) hypothetical protein 0.0071 0.1289 0.4602
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0017 0.0187 0.0434
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0036 0.0583 0.2055
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0019 0.0239 0.0564
Entamoeba histolytica hypothetical protein 0.0043 0.0735 1
Trypanosoma brucei unspecified product 0.0023 0.0325 0.2443
Loa Loa (eye worm) hypothetical protein 0.0012 0.0099 0.0309
Giardia lamblia Heat shock protein HSP 90-alpha 0.0031 0.0487 0.7494
Onchocerca volvulus 0.0017 0.0187 0.1361
Schistosoma mansoni glucose transport protein 0.0117 0.2242 0.5569
Schistosoma mansoni voltage-dependent calcium channel 0.0071 0.1289 0.3187
Plasmodium falciparum calcium-dependent protein kinase 4 0.0036 0.0583 0.0571
Loa Loa (eye worm) latrophilin receptor protein 2 0.0019 0.0238 0.0812
Echinococcus multilocularis Smad4 0.001 0.005 0.0093
Entamoeba histolytica hypothetical protein 0.0043 0.0735 1
Echinococcus multilocularis solute carrier family 22 0.0017 0.0187 0.0434
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0036 0.0583 0.1423
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0187 0.0779
Trypanosoma brucei glucose transporter 2A 0.0036 0.0592 0.454
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0012 0.0099 0.0214
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0012 0.0099 0.0214
Trypanosoma cruzi heat shock protein 85, putative 0.0039 0.0649 0.4988
Schistosoma mansoni hypothetical protein 0.0205 0.4015 1
Toxoplasma gondii LsmAD domain-containing protein 0.003 0.047 0.0693
Echinococcus multilocularis voltage dependent calcium channel 0.0071 0.1289 0.3187
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0071 0.1289 0.3187
Loa Loa (eye worm) hypothetical protein 0.0017 0.0187 0.0626
Leishmania major heat shock protein 83-1 0.0039 0.0649 0.4988
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.047 0.0457
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0012 0.0099 0.0309
Echinococcus granulosus potassium voltage gated channel protein 0.0071 0.1289 0.3187
Trichomonas vaginalis heat shock protein, putative 0.0031 0.0487 0.2124
Leishmania major heat shock protein 83-1 0.0039 0.0649 0.4988
Schistosoma mansoni voltage-gated ion channel 0.0071 0.1289 0.3187
Echinococcus multilocularis solute carrier family 22 0.0017 0.0187 0.0434
Schistosoma mansoni hypothetical protein 0.0071 0.1289 0.3187
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0325 0.2443
Echinococcus multilocularis solute carrier family 22 0.0017 0.0187 0.0434
Toxoplasma gondii lysine-tRNA ligase 0.0026 0.0384 0.0563
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0012 0.0099 0.0214
Loa Loa (eye worm) hypothetical protein 0.0035 0.0568 0.2002
Brugia malayi latrophilin 2 splice variant baaae 0.0041 0.0688 0.2435
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0012 0.0099 0.0214
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0071 0.1289 0.3187
Brugia malayi Isocitrate dehydrogenase 0.0019 0.0239 0.0814
Schistosoma mansoni thyroid hormone receptor 0.0012 0.0099 0.0214
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0012 0.0099 0.0309
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0071 0.1289 0.4603
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0023 0.0325 0.0779
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.0239 0.1769
Loa Loa (eye worm) hypothetical protein 0.0071 0.1289 0.4602
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0019 0.0239 0.1769
Schistosoma mansoni hypothetical protein 0.0041 0.0688 0.1686
Echinococcus multilocularis transfer RNA-Gly 0.0071 0.1289 0.3187
Leishmania major heat shock protein 83-1 0.0039 0.0649 0.4988
Loa Loa (eye worm) Smad1 0.001 0.005 0.0134
Schistosoma mansoni glucose transport protein 0.0117 0.2242 0.5569
Brugia malayi MH1 domain containing protein 0.001 0.005 0.0134
Loa Loa (eye worm) hypothetical protein 0.0071 0.1289 0.4602
Loa Loa (eye worm) hypothetical protein 0.0012 0.0099 0.0309
Echinococcus multilocularis transient receptor potential gamma protein 0.0071 0.1289 0.3187
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.0239 0.0564
Leishmania major heat shock protein 83-1 0.0039 0.0649 0.4988
Echinococcus multilocularis heat shock protein 90 0.0039 0.0649 0.159
Echinococcus multilocularis transient receptor potential cation channel 0.0071 0.1289 0.3187
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0071 0.1289 0.4602
Echinococcus granulosus GPCR family 2 0.0019 0.0238 0.0562
Echinococcus multilocularis short transient receptor potential channel 6 0.0076 0.1392 0.3446
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0071 0.1289 0.3187
Echinococcus granulosus dna polymerase kappa 0.0023 0.0325 0.0779
Echinococcus granulosus solute carrier family 22 0.0017 0.0187 0.0434
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0187 0.0779
Loa Loa (eye worm) hypothetical protein 0.0017 0.0187 0.0626
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0187 0.0779
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0071 0.1289 0.3187
Schistosoma mansoni TGF-beta signal transducer Smad2 0.001 0.005 0.0093
Schistosoma mansoni smad1 5 8 and 0.001 0.005 0.0093
Toxoplasma gondii transporter, cation channel family protein 0.0071 0.1289 0.1934
Echinococcus multilocularis calcium dependent protein kinase 0.0034 0.0537 0.131
Schistosoma mansoni tar DNA-binding protein 0.0076 0.1407 0.3484
Loa Loa (eye worm) hypothetical protein 0.0071 0.1289 0.4602
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0036 0.0583 0.1423
Echinococcus multilocularis conserved hypothetical protein 0.0071 0.1289 0.3187
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0043 0.0735 0.1803
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0035 0.0568 0.1386
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0071 0.1289 0.4602
Trypanosoma brucei glucose transporter, putative 0.0036 0.0592 0.454
Loa Loa (eye worm) hypothetical protein 0.0017 0.0187 0.0626
Trypanosoma brucei heat shock protein 84, putative 0.0016 0.0178 0.1291
Onchocerca volvulus 0.0017 0.0187 0.1361
Echinococcus multilocularis synaptic vesicle 2 protein 0.0017 0.0187 0.0434
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0036 0.0583 0.4466
Echinococcus multilocularis short transient receptor potential channel 6 0.0071 0.1289 0.3187
Trypanosoma cruzi hexose transporter, putative 0.0036 0.0592 0.454
Echinococcus granulosus two pore calcium channel protein 1 0.0071 0.1289 0.3187
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0012 0.0099 0.0214
Loa Loa (eye worm) hypothetical protein 0.0017 0.0187 0.0626
Echinococcus multilocularis transient receptor potential cation channel 0.0071 0.1289 0.3187
Brugia malayi hypothetical protein 0.002 0.025 0.0856
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0012 0.0099 0.0214
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0187 0.0779
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0187 0.0779
Trypanosoma brucei Heat shock protein 83, putative 0.0039 0.0649 0.4988
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0019 0.0238 0.0562
Trypanosoma brucei heat shock protein 90, putative 0.0039 0.0649 0.4988
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0035 0.0568 0.2002
Echinococcus granulosus ecdysone induced protein 78C 0.0012 0.0099 0.0214
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0117 0.2242 0.5569
Toxoplasma gondii hypothetical protein 0.0071 0.1289 0.1934
Brugia malayi ImpB/MucB/SamB family protein 0.0023 0.0325 0.1124
Loa Loa (eye worm) hypothetical protein 0.0035 0.0568 0.2002
Echinococcus granulosus voltage gated potassium channel 0.0071 0.1289 0.3187
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.019 0.3715 0.3706
Plasmodium falciparum lysine--tRNA ligase 0.0026 0.0384 0.0372
Plasmodium vivax sugar transporter, putative 0.0017 0.0187 0.0174
Echinococcus granulosus Smad4 0.001 0.005 0.0093
Loa Loa (eye worm) major facilitator superfamily transporter 0.0017 0.0187 0.0626
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0187 0.0779
Brugia malayi hypothetical protein 0.0017 0.0187 0.0626
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0071 0.1289 0.3187
Trypanosoma brucei glucose transporter, putative 0.0036 0.0592 0.454
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0017 0.0187 0.3666
Echinococcus granulosus transient receptor potential gamma protein 0.0071 0.1289 0.3187
Trypanosoma cruzi heat shock protein 85, putative 0.0039 0.0649 0.4988
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0071 0.1289 0.1934
Brugia malayi olfactory channel protein osm-9 0.0076 0.1392 0.4976
Trypanosoma brucei glucose transporter, putative 0.0036 0.0592 0.454
Trichomonas vaginalis sugar transporter, putative 0.0036 0.0592 0.2598
Plasmodium falciparum calcium-dependent protein kinase 2 0.0036 0.0583 0.0571
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0019 0.0239 0.1769
Loa Loa (eye worm) hypothetical protein 0.0029 0.0433 0.1516
Toxoplasma gondii facilitative glucose transporter GT1 0.0117 0.2242 0.338
Trypanosoma cruzi hexose transporter, putative 0.002 0.0256 0.1903
Trichomonas vaginalis CAMK family protein kinase 0.0036 0.0583 0.2556
Leishmania major heat shock protein 83-1 0.0039 0.0649 0.4988
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0071 0.1289 0.3187
Loa Loa (eye worm) voltage-gated potassium channel 0.0071 0.1289 0.4602
Echinococcus granulosus transient receptor potential cation channel 0.0076 0.1392 0.3446
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0035 0.0568 0.1386
Trichomonas vaginalis glucose transporter, putative 0.0036 0.0592 0.2598
Brugia malayi Smad1 0.001 0.005 0.0134
Schistosoma mansoni hypothetical protein 0.0019 0.0238 0.0562
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0076 0.1407 0.503
Schistosoma mansoni sugar transporter 0.0017 0.0187 0.0434
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0036 0.0583 0.0864
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.047 0.3582
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0187 0.0779
Leishmania major hypothetical protein, conserved 0.003 0.047 0.3582
Trypanosoma brucei glucose transporter, putative 0.0036 0.0592 0.454
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0012 0.0099 0.0309
Echinococcus granulosus heat shock protein 90 0.0039 0.0649 0.159
Loa Loa (eye worm) hypothetical protein 0.0071 0.1289 0.4602
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0019 0.0239 0.0226
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.0239 0.0564
Trypanosoma cruzi hexose transporter, putative 0.0036 0.0592 0.454
Trypanosoma cruzi hexose transporter, putative 0.0036 0.0592 0.454
Echinococcus granulosus hypothetical protein 0.0071 0.1289 0.3187
Entamoeba histolytica deoxycytidyl transferase, putative 0.0023 0.0325 0.4319
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0071 0.1289 0.4602
Schistosoma mansoni smad1 5 8 and 0.001 0.005 0.0093
Echinococcus granulosus solute carrier family 22 0.0017 0.0187 0.0434
Echinococcus multilocularis hyperpolarization activated cyclic 0.0071 0.1289 0.3187
Schistosoma mansoni heat shock protein 0.0039 0.0649 0.159
Leishmania major heat shock protein 83-1 0.0039 0.0649 0.4988
Giardia lamblia Hexose transporter 0.0017 0.0187 0.2876
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0071 0.1289 1
Mycobacterium tuberculosis Conserved hypothetical protein 0.0023 0.0325 0.6582
Onchocerca volvulus 0.0012 0.0099 0.0672
Onchocerca volvulus 0.0017 0.0187 0.1361
Trichomonas vaginalis sugar transporter, putative 0.0036 0.0592 0.2598
Leishmania major lysyl-tRNA synthetase, putative 0.0026 0.0384 0.291
Trypanosoma brucei glucose transporter 1E 0.0036 0.0592 0.454
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0071 0.1289 0.3187
Mycobacterium ulcerans DNA polymerase IV 0.0023 0.0325 0.6582
Onchocerca volvulus 0.0017 0.0187 0.1361
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0023 0.0318 0.137
Trichomonas vaginalis glucose transporter, putative 0.0017 0.0187 0.0779
Onchocerca volvulus 0.0017 0.0187 0.1361
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0014 0.0145 0.0476
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0026 0.0384 0.291
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0071 0.1289 0.3187
Echinococcus multilocularis voltage gated potassium channel 0.0071 0.1289 0.3187
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0019 0.0238 0.0562
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0071 0.1289 0.3187
Trypanosoma brucei PAB1-binding protein , putative 0.003 0.047 0.3582
Schistosoma mansoni endoplasmin 0.0039 0.0649 0.159
Plasmodium vivax heat shock protein 86, putative 0.0039 0.0649 0.0637
Toxoplasma gondii sugar transporter ST1 0.0017 0.0187 0.0263
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0325 0.2443
Schistosoma mansoni tar DNA-binding protein 0.0076 0.1407 0.3484
Leishmania major hypothetical protein, conserved 0.0071 0.1289 1
Brugia malayi hypothetical protein 0.0017 0.0187 0.0626
Plasmodium vivax CDK-related protein kinase 6, putative 0.0499 1 1
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0012 0.0099 0.0309
Echinococcus granulosus short transient receptor potential channel 6 0.0076 0.1392 0.3446
Entamoeba histolytica protein kinase, putative 0.0036 0.0583 0.7894
Echinococcus multilocularis endoplasmin 0.0031 0.0487 0.1183
Brugia malayi isocitrate dehydrogenase 0.0019 0.0239 0.0814
Loa Loa (eye worm) hypothetical protein 0.0071 0.1289 0.4602
Schistosoma mansoni retinoic acid receptor RXR 0.0012 0.0099 0.0214
Echinococcus granulosus heat shock protein 90 0.0031 0.0487 0.1183
Schistosoma mansoni endoplasmin 0.0039 0.0649 0.159
Brugia malayi Major Facilitator Superfamily protein 0.0017 0.0187 0.0626
Loa Loa (eye worm) transcription factor SMAD2 0.0144 0.2785 1
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0036 0.0583 0.0571
Leishmania major DNA polymerase eta, putative 0.0023 0.0325 0.2443
Leishmania major heat shock protein 83-1 0.0039 0.0649 0.4988
Loa Loa (eye worm) pigment dispersing factor receptor c 0.006 0.1076 0.3834
Loa Loa (eye worm) hypothetical protein 0.0071 0.1289 0.4602
Onchocerca volvulus 0.0071 0.1289 1
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0036 0.0583 0.2055
Brugia malayi Sugar transporter family protein 0.0117 0.2242 0.8042
Plasmodium falciparum proline--tRNA ligase 0.0041 0.0687 0.0675
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0071 0.1289 0.4602
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0012 0.0099 0.0309
Schistosoma mansoni voltage-gated potassium channel 0.0071 0.1289 0.3187
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0031 0.0487 1
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0117 0.2242 0.5569
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0017 0.0187 0.3666
Plasmodium falciparum calcium-dependent protein kinase 3 0.0036 0.0583 0.0571
Echinococcus multilocularis sodium channel protein 0.0071 0.1289 0.3187
Schistosoma mansoni voltage-gated potassium channel 0.0071 0.1289 0.3187
Echinococcus granulosus General substrate transporter 0.0101 0.1906 0.4729
Loa Loa (eye worm) hypothetical protein 0.0071 0.1289 0.4602
Echinococcus multilocularis lysyl tRNA synthetase 0.0026 0.0384 0.0927
Giardia lamblia Pms1-like protein 0.0008 0.0013 0.0203
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0325 0.2443
Trypanosoma brucei heat shock protein, putative 0.0039 0.0649 0.4988
Echinococcus granulosus potassium voltage gated channel protein 0.0071 0.1289 0.3187
Leishmania major heat shock protein 83-1 0.0039 0.0649 0.4988
Schistosoma mansoni tar DNA-binding protein 0.0076 0.1407 0.3484
Schistosoma mansoni 60S ribosomal protein L21 0.0071 0.1289 0.3187
Leishmania major heat shock protein 83-1 0.0039 0.0649 0.4988
Echinococcus granulosus smad 0.001 0.005 0.0093
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0035 0.0568 0.2489
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0325 0.2443
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.047 0.0457
Schistosoma mansoni voltage-gated potassium channel 0.0071 0.1289 0.3187
Brugia malayi hypothetical protein 0.003 0.047 0.1648
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0036 0.0583 0.1423
Schistosoma mansoni voltage-gated potassium channel 0.0071 0.1289 0.3187
Onchocerca volvulus Putative transporter 0.0017 0.0187 0.1361
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0071 0.1289 0.3187
Loa Loa (eye worm) hypothetical protein 0.0012 0.0099 0.0309
Loa Loa (eye worm) voltage-gated potassium channel 0.0071 0.1289 0.4602
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0187 0.0779
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0036 0.0583 0.1423
Brugia malayi Nuclear hormone receptor-like 1 0.0012 0.0099 0.0309
Echinococcus granulosus potassium voltage gated channel protein 0.0071 0.1289 0.3187
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0012 0.0099 0.0309
Echinococcus granulosus solute carrier family 22 0.0017 0.0187 0.0434
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0071 0.1289 0.3187
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0187 0.0779
Echinococcus multilocularis sodium leak channel non selective protein 0.0071 0.1289 0.3187
Echinococcus multilocularis hyperpolarization activated cyclic 0.0071 0.1289 0.3187
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0023 0.0325 0.0779
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0071 0.1289 0.3187
Trypanosoma brucei unspecified product 0.0016 0.0178 0.1289
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0012 0.0099 0.0214
Brugia malayi ion channel NompC 0.0071 0.1289 0.4602
Giardia lamblia Sugar-proton symporter 0.0017 0.0187 0.2876
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.0239 0.1769
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0187 0.0779
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0012 0.0099 0.0214
Schistosoma mansoni transient receptor potential channel 4 0.0071 0.1289 0.3187
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0012 0.0099 0.0214
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0014 0.0128 0.0288
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0178 0.1289
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0071 0.1289 0.3187
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0026 0.0384 0.6689
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0325 0.2443
Trypanosoma brucei heat shock protein, putative 0.0039 0.0649 0.4988
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0071 0.1289 0.3187
Echinococcus multilocularis potassium voltage gated channel protein 0.0071 0.1289 0.3187
Leishmania major heat shock protein 83-1 0.0039 0.0649 0.4988
Trypanosoma brucei THT1 - hexose transporter, putative 0.0036 0.0592 0.454
Loa Loa (eye worm) hypothetical protein 0.0041 0.0688 0.2435
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0187 0.0779
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0041 0.0687 0.1022
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0014 0.0128 0.0288
Echinococcus multilocularis shaker cognate 0.0071 0.1289 0.3187
Echinococcus multilocularis heat shock protein 0.0039 0.0649 0.159
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0187 0.0779
Schistosoma mansoni transient receptor potential channel 0.0076 0.1392 0.3446
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.006 0.1076 0.3834
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0035 0.0568 1
Echinococcus multilocularis ecdysone induced protein 78C 0.0012 0.0099 0.0214
Loa Loa (eye worm) hypothetical protein 0.003 0.047 0.1648
Loa Loa (eye worm) hypothetical protein 0.0023 0.0325 0.1124
Echinococcus multilocularis GPCR, family 2 0.0019 0.0238 0.0562
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0023 0.0325 0.0779
Leishmania major heat shock protein 83-1 0.0039 0.0649 0.4988
Schistosoma mansoni voltage-gated potassium channel 0.0071 0.1289 0.3187
Loa Loa (eye worm) hypothetical protein 0.0017 0.0187 0.0626
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0012 0.0099 0.0309
Plasmodium falciparum mitogen-activated protein kinase 2 0.019 0.3715 0.3706
Brugia malayi MH2 domain containing protein 0.0144 0.2785 1
Trichomonas vaginalis heat shock protein, putative 0.0031 0.0487 0.2124
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0187 0.0779
Trypanosoma cruzi heat shock protein 90, putative 0.0039 0.0649 0.4988
Echinococcus granulosus voltage gated potassium channel 0.0071 0.1289 0.3187
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0071 0.1289 0.3187
Echinococcus multilocularis smad 0.001 0.005 0.0093
Schistosoma mansoni protein kinase 0.0036 0.0583 0.1423
Brugia malayi nuclear hormone receptor 0.0012 0.0099 0.0309
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0016 0.0178 0.1291
Trypanosoma cruzi sugar transporter, putative 0.0017 0.0187 0.1361
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0071 0.1289 0.3187
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0187 0.0779
Schistosoma mansoni transient receptor potential channel 0.0071 0.1289 0.3187
Echinococcus granulosus ryanodine receptor 44f 0.0071 0.1289 0.3188
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0012 0.0099 0.0309
Schistosoma mansoni hypothetical protein 0.0019 0.0238 0.0562
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0012 0.0099 0.0309
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0071 0.1289 0.3187
Mycobacterium ulcerans integral membrane transport protein 0.0017 0.0187 0.3666
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0023 0.0325 0.6582
Trypanosoma brucei glucose transporter, putative 0.0036 0.0592 0.454
Loa Loa (eye worm) sugar transporter 0.0117 0.2242 0.8042
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0012 0.0099 0.0309
Trypanosoma brucei heat shock protein, putative 0.0039 0.0649 0.4988
Leishmania major glucose transporter, lmgt1 0.0036 0.0592 0.454
Schistosoma mansoni nuclear hormone receptor 0.0012 0.0099 0.0214
Echinococcus granulosus calcium activated potassium channel 0.0073 0.1334 0.3301
Leishmania major hypothetical protein, conserved 0.0017 0.0187 0.1361
Echinococcus multilocularis potassium voltage gated channel protein 0.0071 0.1289 0.3187
Schistosoma mansoni voltage-gated potassium channel 0.0071 0.1289 0.3187
Schistosoma mansoni smad 0.001 0.005 0.0093
Entamoeba histolytica hypothetical protein 0.0043 0.0735 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0178 0.1289
Loa Loa (eye worm) hypothetical protein 0.0012 0.0099 0.0309
Loa Loa (eye worm) hypothetical protein 0.0017 0.0187 0.0626
Schistosoma mansoni hypothetical protein 0.0205 0.4015 1
Plasmodium vivax ataxin-2 like protein, putative 0.003 0.047 0.0457
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0187 0.0779
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0178 0.1289
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0187 0.0779
Loa Loa (eye worm) heat shock protein 90 0.0039 0.0649 0.2295
Brugia malayi Latrophilin receptor protein 2 0.0019 0.0238 0.0812
Toxoplasma gondii transporter, cation channel family protein 0.0071 0.1289 0.1934
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0071 0.1289 0.3187
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0036 0.0583 0.1423
Trypanosoma cruzi Heat shock protein 83, putative 0.0039 0.0649 0.4988
Trypanosoma cruzi heat shock protein 85, putative 0.0031 0.0487 0.3712
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0012 0.0099 0.0214
Loa Loa (eye worm) hypothetical protein 0.0012 0.0099 0.0309
Brugia malayi lysyl-tRNA synthetase 0.0026 0.0384 0.1339
Schistosoma mansoni voltage-gated potassium channel 0.0071 0.1289 0.3187
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0071 0.1289 0.3187
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0036 0.0583 0.0864
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0117 0.2242 0.5569
Loa Loa (eye worm) hypothetical protein 0.0019 0.0238 0.0812
Giardia lamblia Lysyl-tRNA synthetase 0.0026 0.0384 0.5918
Treponema pallidum prolyl-tRNA synthetase 0.0012 0.0104 0.1916
Trichomonas vaginalis sugar transporter, putative 0.0036 0.0592 0.2598
Schistosoma mansoni DNA polymerase eta 0.0023 0.0325 0.0779
Trypanosoma brucei heat shock protein, putative 0.0039 0.0649 0.4988
Leishmania major protein kinase, putative 0.0036 0.0583 0.4466
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0041 0.0687 0.5282
Trichomonas vaginalis heat shock protein, putative 0.0031 0.0487 0.2124
Echinococcus granulosus potassium voltage gated channel protein 0.0071 0.1289 0.3187
Trichomonas vaginalis DNA polymerase eta, putative 0.0023 0.0325 0.1398
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0022 0.0304 0.5239
Leishmania major heat shock protein 83-1 0.0039 0.0649 0.4988
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0071 0.1289 1
Loa Loa (eye worm) hypothetical protein 0.0071 0.1289 0.4602
Brugia malayi hypothetical protein 0.0017 0.0187 0.0626
Brugia malayi nuclear receptor NHR-88 0.0012 0.0099 0.0309
Trypanosoma brucei heat shock protein, putative 0.0039 0.0649 0.4988
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0071 0.1289 0.3187
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0071 0.1289 0.3187
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0187 0.0779
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0071 0.1289 0.3187
Giardia lamblia Heat shock protein HSP 90-alpha 0.0039 0.0649 1
Loa Loa (eye worm) major facilitator superfamily transporter 0.0017 0.0187 0.0626
Trypanosoma brucei THT1 - hexose transporter, putative 0.0036 0.0592 0.454
Toxoplasma gondii hypothetical protein 0.0071 0.1289 0.1934
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0071 0.1289 0.3187
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0187 0.0779
Loa Loa (eye worm) hypothetical protein 0.0036 0.0583 0.2055
Plasmodium falciparum calcium-dependent protein kinase 5 0.0036 0.0583 0.0571
Echinococcus multilocularis transient receptor potential cation channel 0.0071 0.1289 0.3187
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0187 0.0779
Leishmania major glucose transporter, lmgt3 0.0036 0.0592 0.454
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0325 0.2443
Brugia malayi TAR-binding protein 0.0076 0.1407 0.503
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0325 0.2443
Trypanosoma cruzi DNA polymerase eta, putative 0.0023 0.0325 0.2443
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0071 0.1289 0.3187
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0071 0.1289 0.3187
Schistosoma mansoni smad1 5 8 and 0.001 0.005 0.0093
Brugia malayi photoreceptor-specific nuclear receptor 0.0012 0.0099 0.0309
Schistosoma mansoni voltage-gated potassium channel 0.0071 0.1289 0.3187
Brugia malayi Steroid receptor seven-up type 2 0.0012 0.0099 0.0309
Trichomonas vaginalis glucose transporter, putative 0.0036 0.0592 0.2598
Plasmodium falciparum endoplasmin, putative 0.0024 0.034 0.0328
Brugia malayi RNA recognition motif domain containing protein 0.0076 0.1407 0.503
Echinococcus multilocularis solute carrier family 22 0.0017 0.0187 0.0434
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0012 0.0099 0.0214
Loa Loa (eye worm) voltage-gated calcium channel 0.0071 0.1289 0.4602
Brugia malayi Cam kinase protein 1 0.0036 0.0583 0.2055
Loa Loa (eye worm) calcium channel 0.0071 0.1289 0.4602
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0187 0.0779
Brugia malayi ImpB/MucB/SamB family protein 0.0023 0.0325 0.1124
Echinococcus granulosus synaptic vesicle 2 protein 0.0017 0.0187 0.0434
Trypanosoma cruzi heat shock protein, putative 0.0016 0.0178 0.1291
Loa Loa (eye worm) hypothetical protein 0.0071 0.1289 0.4602
Schistosoma mansoni voltage-gated potassium channel 0.0071 0.1289 0.3187
Echinococcus granulosus dna polymerase eta 0.0023 0.0325 0.0779
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0022 0.0304 0.6138
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0325 0.2443
Plasmodium vivax heat shock protein, putative 0.0016 0.0178 0.0165
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0031 0.0487 0.3712
Onchocerca volvulus 0.0017 0.0187 0.1361
Echinococcus multilocularis voltage gated potassium channel 0.0071 0.1289 0.3187
Loa Loa (eye worm) hypothetical protein 0.0017 0.0187 0.0626
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0031 0.0487 1
Echinococcus granulosus calcium dependent protein kinase 0.0034 0.0537 0.131
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0325 0.2443
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0071 0.1289 0.3187
Loa Loa (eye worm) hypothetical protein 0.0017 0.0187 0.0626
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0012 0.0099 0.0214
Onchocerca volvulus 0.0017 0.0187 0.1361
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0071 0.1289 0.3187
Schistosoma mansoni sugar transporter 0.0017 0.0187 0.0434
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0026 0.0384 0.1665
Brugia malayi major facilitator superfamily protein 0.0017 0.0187 0.0626
Echinococcus multilocularis General substrate transporter 0.0101 0.1906 0.4729
Leishmania major glucose transporter, lmgt2 0.0036 0.0592 0.454
Brugia malayi Major Facilitator Superfamily protein 0.0017 0.0187 0.0626
Toxoplasma gondii sugar transporter ST3 0.0017 0.0187 0.0263
Loa Loa (eye worm) hypothetical protein 0.0017 0.0187 0.0626
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0187 0.0779
Schistosoma mansoni serine/threonine protein kinase 0.0036 0.0583 0.1423
Loa Loa (eye worm) hypothetical protein 0.0017 0.0187 0.0626
Trypanosoma cruzi hexose transporter, putative 0.0017 0.0187 0.1361
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0071 0.1289 0.3187
Schistosoma mansoni sugar transporter 0.0017 0.0187 0.0434
Echinococcus granulosus shaker cognate 0.0071 0.1289 0.3187
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0016 0.0178 0.0411
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0012 0.0099 0.0214
Onchocerca volvulus Protein ultraspiracle homolog 0.0012 0.0099 0.0672
Brugia malayi MH1 domain containing protein 0.001 0.005 0.0134
Loa Loa (eye worm) hypothetical protein 0.0071 0.1289 0.4602
Loa Loa (eye worm) isocitrate dehydrogenase 0.0019 0.0239 0.0814
Schistosoma mansoni hypothetical protein 0.0043 0.0735 0.1803
Leishmania major DNA polymerase kappa, putative 0.0023 0.0325 0.2443
Schistosoma mansoni voltage-gated cation channel 0.0071 0.1289 0.3187
Brugia malayi major facilitator superfamily protein 0.0017 0.0187 0.0626
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0071 0.1289 0.4602
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0012 0.0099 0.0309
Echinococcus granulosus hyperpolarization activated cyclic 0.0071 0.1289 0.3187
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0117 0.2242 0.5569
Giardia lamblia DINP protein human, muc B family 0.0023 0.0325 0.5002
Trypanosoma brucei heat shock protein, putative 0.0039 0.0649 0.4988
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0071 0.1289 0.3187
Echinococcus granulosus Sugar transporter ERD6 protein 0.0017 0.0187 0.0434
Echinococcus multilocularis dna polymerase kappa 0.0023 0.0325 0.0779
Loa Loa (eye worm) hypothetical protein 0.0071 0.1289 0.4602
Toxoplasma gondii heat shock protein 75, putative 0.0016 0.0178 0.025
Leishmania major heat shock protein 83-1 0.0039 0.0649 0.4988
Loa Loa (eye worm) hypothetical protein 0.006 0.1076 0.3834
Loa Loa (eye worm) hypothetical protein 0.0017 0.0187 0.0626
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0187 0.0779
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0071 0.1289 0.4602
Loa Loa (eye worm) hypothetical protein 0.0026 0.0384 0.1339
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0019 0.0238 0.0562
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0187 0.0779
Toxoplasma gondii heat shock protein 90, putative 0.0039 0.0649 0.0965
Brugia malayi heat shock protein 90 0.0039 0.0649 0.2295
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0012 0.0099 0.0214
Echinococcus granulosus FTZ F1 alpha 0.0012 0.0099 0.0214
Schistosoma mansoni voltage-gated potassium channel 0.0071 0.1289 0.3187
Echinococcus multilocularis calcium activated potassium channel 0.0073 0.1334 0.3301
Leishmania major glucose transporter/membrane transporter D2, putative 0.0036 0.0592 0.454
Onchocerca volvulus 0.0017 0.0187 0.1361
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0041 0.0687 0.5282
Loa Loa (eye worm) hypothetical protein 0.0012 0.0099 0.0309
Onchocerca volvulus 0.0017 0.0187 0.1361
Trypanosoma brucei unspecified product 0.0016 0.0178 0.1289
Plasmodium falciparum calcium-dependent protein kinase 1 0.0036 0.0583 0.0571
Plasmodium vivax hexose transporter 0.0117 0.2242 0.2232
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0071 0.1289 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0187 0.0626
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0019 0.0238 0.0562
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0016 0.0178 0.2282
Trichomonas vaginalis sugar transport protein, putative 0.0017 0.0187 0.0779
Loa Loa (eye worm) endoplasmin 0.0039 0.0649 0.2295
Schistosoma mansoni ryanodine receptor related 0.0071 0.1289 0.3188
Schistosoma mansoni heat shock protein 0.0039 0.0649 0.159
Leishmania major heat shock protein 83-1 0.0039 0.0649 0.4988
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0071 0.1289 0.3187
Plasmodium falciparum heat shock protein 90 0.0039 0.0649 0.0637
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0036 0.0583 0.0571
Trypanosoma brucei heat shock protein, putative 0.0039 0.0649 0.4988
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0117 0.2242 0.5569
Leishmania major heat shock protein 83-1 0.0039 0.0649 0.4988
Toxoplasma gondii sugar transporter ST2 0.0017 0.0187 0.0263
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0071 0.1289 0.3187
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0012 0.0099 0.0309
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0187 0.0779
Brugia malayi MH2 domain containing protein 0.001 0.005 0.0134
Loa Loa (eye worm) hypothetical protein 0.0071 0.1289 0.4602
Schistosoma mansoni voltage-gated potassium channel 0.0071 0.1289 0.3187
Loa Loa (eye worm) ryanodine receptor 0.0071 0.1289 0.4602
Schistosoma mansoni voltage-gated potassium channel 0.0071 0.1289 0.3187
Entamoeba histolytica heat shock protein 90, putative 0.0039 0.0649 0.8816
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0036 0.0583 0.0864
Echinococcus granulosus voltage dependent calcium channel 0.0071 0.1289 0.3187
Onchocerca volvulus Bile acid receptor homolog 0.0012 0.0099 0.0672
Plasmodium vivax proline--tRNA ligase, putative 0.0041 0.0687 0.0675
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0017 0.0187 0.3666
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0019 0.0239 0.0564
Trichomonas vaginalis heat shock protein, putative 0.0016 0.0178 0.0739
Schistosoma mansoni voltage-gated potassium channel 0.0071 0.1289 0.3187
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0036 0.0583 0.2055
Chlamydia trachomatis proline--tRNA ligase 0.0012 0.0104 0.2445
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0012 0.0099 0.0214
Brugia malayi Sugar transporter family protein 0.0017 0.0187 0.0626
Leishmania major hypothetical protein, unknown function 0.0071 0.1289 1
Trichomonas vaginalis heat shock protein, putative 0.0039 0.0649 0.2854
Trypanosoma brucei sugar transporter, putative 0.0017 0.0187 0.1361
Brugia malayi hypothetical protein 0.0043 0.0735 0.2603
Brugia malayi voltage-dependent calcium channel 0.0071 0.1289 0.4602
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0592 0.2598
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0012 0.0099 0.0309
Echinococcus multilocularis isocitrate dehydrogenase 0.0019 0.0239 0.0564
Schistosoma mansoni tar DNA-binding protein 0.0076 0.1407 0.3484
Leishmania major heat shock protein 83-1 0.0039 0.0649 0.4988
Brugia malayi cation channel family protein 0.0071 0.1289 0.4602
Echinococcus granulosus hyperpolarization activated cyclic 0.0071 0.1289 0.3187
Echinococcus multilocularis ryanodine receptor 44f 0.0071 0.1289 0.3188
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0017 0.0187 0.3666
Schistosoma mansoni hypothetical protein 0.0014 0.0128 0.0288
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0012 0.0099 0.0214
Echinococcus granulosus transient receptor potential cation channel 0.0071 0.1289 0.3187
Loa Loa (eye worm) hypothetical protein 0.0071 0.1289 0.4602
Schistosoma mansoni protein kinase 0.0036 0.0583 0.1423
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0187 0.0779
Echinococcus granulosus voltage gated hydrogen channel 1 0.0071 0.1289 0.3187
Brugia malayi Transient-receptor-potential like protein 0.0071 0.1289 0.4602
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0071 0.1289 0.3187
Echinococcus granulosus voltage dependent calcium channel 0.0071 0.1289 0.3187
Schistosoma mansoni voltage-gated potassium channel 0.0071 0.1289 0.3187
Schistosoma mansoni voltage-gated potassium channel 0.0071 0.1289 0.3187
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0041 0.0687 0.5282
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0325 0.2443
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0036 0.0583 0.1423
Echinococcus multilocularis transient receptor potential cation channel 0.0071 0.1289 0.3187
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0071 0.1289 0.3187
Echinococcus granulosus potassium voltage gated channel protein 0.0071 0.1289 0.3187
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0012 0.0099 0.0309
Chlamydia trachomatis lysine--tRNA ligase 0.0026 0.0384 1
Trypanosoma cruzi glucose transporter, putative 0.0017 0.0187 0.1361
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0016 0.0178 0.0411
Loa Loa (eye worm) hypothetical protein 0.0012 0.0099 0.0309
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0325 0.2443
Loa Loa (eye worm) RNA binding protein 0.0076 0.1407 0.503
Trypanosoma cruzi heat shock protein 90, putative 0.0023 0.0322 0.2421
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0071 0.1289 0.3187
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0036 0.0583 0.0571
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0071 0.1289 0.4602
Trypanosoma cruzi heat shock protein 90, putative 0.0031 0.0487 0.3712
Echinococcus granulosus two pore calcium channel protein 2 0.0071 0.1289 0.3187
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0325 0.2443
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0187 0.0779
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0071 0.1289 0.4602
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0071 0.1289 0.1934
Trichomonas vaginalis endoplasmin, putative 0.0024 0.034 0.1469
Echinococcus multilocularis potassium voltage gated channel protein 0.0071 0.1289 0.3187
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0035 0.0568 0.1386
Leishmania major myo-inositol/proton symporter (MIT) 0.0017 0.0187 0.1361
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0071 0.1289 0.4602
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0187 0.0779
Giardia lamblia Grp94/Hsp90 0.0031 0.0487 0.7494
Plasmodium vivax heat shock protein 90, putative 0.0016 0.0178 0.0165
Toxoplasma gondii Hsp90 domain-containing protein 0.0016 0.0178 0.025
Brugia malayi Calcitonin receptor-like protein seb-1 0.006 0.1076 0.3834
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0071 0.1289 0.3187
Schistosoma mansoni voltage-gated potassium channel 0.0071 0.1289 0.3187
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0187 0.0779
Trichomonas vaginalis myo-inositol transporter, putative 0.0017 0.0187 0.0779
Leishmania major heat shock protein, putative 0.0016 0.0178 0.1291
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0117 0.2242 0.5569
Onchocerca volvulus 0.0017 0.0187 0.1361
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0035 0.0568 0.2002
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0187 0.0779
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0023 0.0325 0.1398
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0012 0.0099 0.0672
Onchocerca volvulus 0.0017 0.0187 0.1361
Schistosoma mansoni RAR-like nuclear receptor 0.0012 0.0099 0.0214
Brugia malayi cation channel family protein 0.0071 0.1289 0.4602
Schistosoma mansoni glucose transporter 0.0017 0.0187 0.0434
Schistosoma mansoni calcium-activated potassium channel 0.0071 0.1289 0.3187
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0071 0.1289 0.5722
Schistosoma mansoni steroid hormone receptor ad4bp 0.0012 0.0099 0.0214
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0035 0.0568 0.7688
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0036 0.0583 0.1423
Trypanosoma brucei glucose transporter, putative 0.0036 0.0592 0.454
Schistosoma mansoni hypothetical protein 0.0117 0.2242 0.5569
Trypanosoma brucei glucose transporter, putative 0.0036 0.0592 0.454
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0071 0.1289 0.3187
Echinococcus granulosus TRP transient receptor potential channel 0.0071 0.1289 0.3187
Echinococcus granulosus TGF beta signal transducer SmadC 0.001 0.005 0.0093
Treponema pallidum heat shock protein 90 0.0031 0.0487 1
Loa Loa (eye worm) sugar transporter 0.0017 0.0187 0.0626
Echinococcus granulosus transient receptor potential cation channel 0.0071 0.1289 0.3187
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0012 0.0099 0.0214
Brugia malayi Cyclic-nucleotide gated cation channel 0.0071 0.1289 0.4602
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0017 0.0187 0.0434
Brugia malayi RNA binding protein 0.0076 0.1407 0.503
Echinococcus multilocularis heat shock protein 90 0.0031 0.0487 0.1183
Schistosoma mansoni terminal deoxycytidyl transferase 0.0023 0.0325 0.0779
Echinococcus granulosus geminin 0.0205 0.4015 1
Onchocerca volvulus 0.0017 0.0187 0.1361
Echinococcus granulosus heat shock protein 0.0039 0.0649 0.159
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0012 0.0099 0.0214
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0325 0.2443
Loa Loa (eye worm) hypothetical protein 0.0071 0.1289 0.4602
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0012 0.0099 0.0309
Brugia malayi Major Facilitator Superfamily protein 0.0017 0.0187 0.0626
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0325 0.2443
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0071 0.1289 0.4602
Toxoplasma gondii protein kinase, putative 0.0332 0.6607 1
Toxoplasma gondii transporter, cation channel family protein 0.0071 0.1289 0.1934
Brugia malayi Sugar transporter family protein 0.0017 0.0187 0.0626
Plasmodium vivax calcium-dependent protein kinase, putative 0.0036 0.0583 0.0571
Mycobacterium ulcerans heat shock protein 90 0.0031 0.0487 1
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0187 0.0779
Toxoplasma gondii heat shock protein HSP90 0.0039 0.0649 0.0965
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0187 0.0779
Echinococcus granulosus endoplasmin 0.0031 0.0487 0.1183
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0043 0.0735 0.1803
Brugia malayi Endoplasmin precursor 0.0039 0.0649 0.2295
Trypanosoma cruzi hexose transporter 0.0036 0.0592 0.454
Entamoeba histolytica protein kinase, putative 0.0036 0.0583 0.7894
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0071 0.1289 0.3187
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0035 0.0568 0.1386
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0071 0.1289 0.3187
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0071 0.1289 0.4602
Plasmodium falciparum hexose transporter 0.0117 0.2242 0.2232
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0012 0.0099 0.0214
Loa Loa (eye worm) heat shock protein 75 0.0016 0.0178 0.0594
Plasmodium vivax endoplasmin, putative 0.0039 0.0649 0.0637
Schistosoma mansoni two-pore calcium channel 0.0071 0.1289 0.3187
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0071 0.1289 0.3187
Loa Loa (eye worm) hypothetical protein 0.0071 0.1289 0.4602
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0071 0.1289 0.3187
Echinococcus granulosus transient receptor potential cation channel 0.0071 0.1289 0.3187
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0071 0.1289 0.3187
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0187 0.0779
Schistosoma mansoni glucose transport protein 0.0117 0.2242 0.5569
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0071 0.1289 0.4602
Echinococcus multilocularis mothers against decapentaplegic 5 0.001 0.005 0.0093
Schistosoma mansoni thyroid hormone receptor 0.0012 0.0099 0.0214
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0017 0.0187 0.0174
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0017 0.0187 0.1361
Echinococcus multilocularis FTZ F1 alpha 0.0012 0.0099 0.0214
Entamoeba histolytica hypothetical protein 0.0043 0.0735 1
Mycobacterium ulcerans sugar transporter 0.0017 0.0187 0.3666
Echinococcus multilocularis geminin 0.0205 0.4015 1
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0592 0.2598
Plasmodium falciparum heat shock protein 90, putative 0.0016 0.0178 0.0165
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0071 0.1289 0.3187
Toxoplasma gondii transporter, major facilitator family protein 0.0017 0.0187 0.0263
Loa Loa (eye worm) TAR-binding protein 0.0076 0.1407 0.503
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0071 0.1289 0.3187
Loa Loa (eye worm) hypothetical protein 0.0071 0.1289 0.4602
Echinococcus multilocularis potassium voltage gated channel protein 0.0071 0.1289 0.3187
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0071 0.1289 0.4602
Loa Loa (eye worm) hypothetical protein 0.0017 0.0187 0.0626
Schistosoma mansoni transient receptor potential channel 0.0071 0.1289 0.3187
Schistosoma mansoni protein kinase 0.0036 0.0583 0.1423
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0071 0.1289 0.4602
Loa Loa (eye worm) voltage-dependent calcium channel 0.0071 0.1289 0.4602
Echinococcus multilocularis two pore calcium channel protein 2 0.0071 0.1289 0.3187
Mycobacterium ulcerans DNA polymerase IV 0.0023 0.0325 0.6582
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0012 0.0099 0.0309
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0325 0.2443
Schistosoma mansoni voltage-gated potassium channel 0.0071 0.1289 0.3187
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0071 0.1289 0.3187
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0012 0.0099 0.0309
Leishmania major heat shock protein 83-1 0.0039 0.0649 0.4988
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0012 0.0104 0.1916
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0012 0.0099 0.0309
Schistosoma mansoni sugar transporter 0.0017 0.0187 0.0434
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0071 0.1289 0.3187
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0071 0.1289 0.4602
Loa Loa (eye worm) MH2 domain-containing protein 0.0144 0.2785 1
Echinococcus granulosus sodium channel protein 0.0071 0.1289 0.3187
Onchocerca volvulus 0.0017 0.0187 0.1361
Schistosoma mansoni vesicular amine transporter 0.0071 0.1289 0.3187
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0071 0.1289 0.3187
Loa Loa (eye worm) MH1 domain-containing protein 0.001 0.005 0.0134
Brugia malayi steroid hormone receptor 0.0012 0.0099 0.0309
Brugia malayi MH2 domain containing protein 0.001 0.005 0.0134
Loa Loa (eye worm) hypothetical protein 0.0017 0.0187 0.0626
Brugia malayi hypothetical protein 0.0071 0.1289 0.4602
Plasmodium falciparum protein kinase 7 0.0332 0.6607 0.6602
Plasmodium falciparum heat shock protein 90, putative 0.0016 0.0178 0.0165
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0041 0.0687 0.5282
Echinococcus granulosus lysyl tRNA synthetase 0.0026 0.0384 0.0927
Onchocerca volvulus 0.0017 0.0187 0.1361
Echinococcus multilocularis tar DNA binding protein 0.0076 0.1407 0.3484
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0117 0.2242 0.5569
Trypanosoma brucei heat shock protein 90, putative 0.0039 0.0649 0.4988
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0023 0.0325 0.2443
Loa Loa (eye worm) ion channel NompC 0.0071 0.1289 0.4602
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0071 0.1289 0.5722
Loa Loa (eye worm) hypothetical protein 0.0071 0.1289 0.4602
Schistosoma mansoni lysyl-tRNA synthetase 0.0026 0.0384 0.0927
Loa Loa (eye worm) hypothetical protein 0.0012 0.0099 0.0309
Loa Loa (eye worm) hypothetical protein 0.0071 0.1289 0.4602
Echinococcus granulosus short transient receptor potential channel 6 0.0071 0.1289 0.3187
Schistosoma mansoni tar DNA-binding protein 0.0076 0.1407 0.3484
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0071 0.1289 0.3187
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0071 0.1289 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0187 0.0626
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.047 0.3582
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0017 0.0187 0.3666
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0325 0.2443
Echinococcus multilocularis potassium large conductance calcium activated 0.0071 0.1289 0.3187
Entamoeba histolytica heat shock protein 90, putative 0.0039 0.0649 0.8816
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0071 0.1289 1
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0071 0.1289 0.3187
Schistosoma mansoni hypothetical protein 0.0019 0.0238 0.0562
Schistosoma mansoni voltage-gated potassium channel 0.0071 0.1289 0.3187
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0019 0.0239 0.0564
Trichomonas vaginalis heat shock protein, putative 0.0024 0.034 0.1469
Schistosoma mansoni lysyl-tRNA synthetase 0.0026 0.0384 0.0927
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0187 0.0779
Schistosoma mansoni transcription factor LCR-F1 0.0043 0.0735 0.1803
Echinococcus granulosus transient receptor potential cation channel 0.0071 0.1289 0.3187
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0031 0.0487 0.8535
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0187 0.0779
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0019 0.0239 0.0226
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0187 0.0779
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0026 0.0384 0.7838
Entamoeba histolytica hypothetical protein 0.0026 0.0384 0.5143
Echinococcus granulosus potassium large conductance calcium activated 0.0071 0.1289 0.3187
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0026 0.0384 0.291
Plasmodium vivax lysine--tRNA ligase, putative 0.0026 0.0384 0.0372
Onchocerca volvulus 0.0017 0.0187 0.1361
Toxoplasma gondii isocitrate dehydrogenase 0.0019 0.0239 0.0342
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.019 0.3715 0.5614
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0012 0.0099 0.0309
Echinococcus multilocularis transient receptor potential cation channel 0.0076 0.1392 0.3446
Schistosoma mansoni heat shock protein 0.0016 0.0178 0.0411
Loa Loa (eye worm) hypothetical protein 0.0076 0.1392 0.4976
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0187 0.0779
Toxoplasma gondii isocitrate dehydrogenase 0.0019 0.0239 0.0342
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.0239 0.1769
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0019 0.0239 0.4765
Echinococcus granulosus transient receptor potential cation channel 0.0071 0.1289 0.3187
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0071 0.1289 0.3187
Loa Loa (eye worm) MH2 domain-containing protein 0.001 0.005 0.0134
Trypanosoma brucei THT1 - hexose transporter, putative 0.0036 0.0592 0.454
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0071 0.1289 1
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0117 0.2242 0.5569
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0071 0.1289 0.4602
Loa Loa (eye worm) hypothetical protein 0.0071 0.1289 0.4602

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) 14.481 uM PUBCHEM_BIOASSAY: Discovery of Small Molecule Probes for H1N1 Influenza NS1A. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504399] ChEMBL. No reference
Potency (functional) 0.3981 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b: Cytotox Counterscreen. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588855, AID588860] ChEMBL. No reference
Potency (functional) 1.1582 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 1.9953 uM PubChem BioAssay. qHTS for Inhibitors of ATXN expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 2.2387 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of binding or entry into cells for Lassa Virus. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463114, AID540249] ChEMBL. No reference
Potency (functional) 3.1623 uM PubChem BioAssay. qHTS for Activators of Integrin-Mediated Alleviation for Muscular Dystrophy. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 7.0795 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 31.6228 uM PubChem BioAssay. qHTS Assay for Inhibitors of the HIV-1 protein Vpr. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 100 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of JMJD2A-Tudor Domain. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504402] ChEMBL. No reference
Potency (functional) 100 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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