Detailed information for compound 1560154

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 646.738 | Formula: C29H46N10O7
  • H donors: 9 H acceptors: 9 LogP: -1.62 Rotable bonds: 23
    Rule of 5 violations (Lipinski): 3
  • SMILES: NC[C@@H](NC(=O)c1[nH]cnc1C(=O)N[C@H](C(=O)CNC[C@@H](NC(=O)c1[nH]cnc1C(=O)N[C@H](C(=O)O)CC(C)C)C)C)CC(C)C
  • InChi: 1S/C29H46N10O7/c1-14(2)7-18(9-30)38-27(43)23-22(33-13-34-23)26(42)37-17(6)20(40)11-31-10-16(5)36-25(41)21-24(35-12-32-21)28(44)39-19(29(45)46)8-15(3)4/h12-19,31H,7-11,30H2,1-6H3,(H,32,35)(H,33,34)(H,36,41)(H,37,42)(H,38,43)(H,39,44)(H,45,46)/t16-,17-,18-,19-/m0/s1
  • InChiKey: CTGFWUYSEKFQQP-VJANTYMQSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0023 0.0102 0.0782
Echinococcus granulosus rhodopsin orphan GPCR 0.0048 0.0254 0.0238
Echinococcus granulosus thioredoxin glutathione reductase 0.0048 0.0254 0.0238
Schistosoma mansoni biogenic amine receptor 0.0048 0.0254 0.0254
Echinococcus multilocularis g protein coupled receptor 0.0048 0.0254 0.0238
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0048 0.0254 0.0254
Loa Loa (eye worm) hypothetical protein 0.0048 0.0254 0.0968
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0155 0.106
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0019 0.0077 0.0244
Trichomonas vaginalis DNA helicase recq1, putative 0.0022 0.0093 0.0329
Schistosoma mansoni neuropeptide receptor 0.0048 0.0254 0.0254
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0074 0.0413 0.3045
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0063 0.0327
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0023 0.0102 0.0632
Loa Loa (eye worm) hypothetical protein 0.0048 0.0254 0.0968
Toxoplasma gondii 6-phosphofructokinase 0.0059 0.0317 0.2758
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0023 0.0102 0.0347
Trypanosoma cruzi adenylate kinase, putative 0.0035 0.0176 0.1229
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0023 0.0102 0.0632
Brugia malayi larval opioid receptor 0.0048 0.0254 0.0968
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0023 0.0102 0.0358
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0063 0.0327
Plasmodium falciparum adenylate kinase 0.0049 0.0256 0.0963
Mycobacterium leprae PROBABLE ADENYLATE KINASE KAD (ATP-AMP TRANSPHOSPHORYLASE) 0.0016 0.0057 0.0069
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0023 0.0102 0.0358
Brugia malayi hypothetical protein 0.0048 0.0254 0.0968
Trichomonas vaginalis phosphofructokinase, putative 0.0059 0.0317 0.1122
Echinococcus multilocularis rhodopsin orphan GPCR 0.0048 0.0254 0.0238
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0074 0.0413 0.1616
Echinococcus multilocularis ectonucleoside triphosphate diphosphohydrolase 0.042 0.2508 0.2496
Loa Loa (eye worm) hypothetical protein 0.0074 0.0413 0.1616
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0014 0.0048 0.0032
Echinococcus granulosus peptide allatostatin:somatostatin 0.0048 0.0254 0.0238
Echinococcus multilocularis neuropeptide receptor A26 0.0495 0.2958 0.2947
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0048 0.0254 0.1758
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0074 0.0413 0.1591
Plasmodium falciparum thioredoxin reductase 0.0017 0.0063 0.0188
Onchocerca volvulus 0.0048 0.0254 0.0745
Loa Loa (eye worm) hypothetical protein 0.0013 0.0039 0.0092
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0048 0.0254 0.0238
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0017 0.0063 0.0047
Echinococcus granulosus neuropeptides capa receptor 0.0048 0.0254 0.0238
Trichomonas vaginalis NADH dehydrogenase 51 kDa subunit, putative 0.0049 0.0256 0.0908
Trichomonas vaginalis guanosine-diphosphatase, putative 0.004 0.0202 0.0714
Loa Loa (eye worm) hypothetical protein 0.0048 0.0254 0.0968
Brugia malayi Pre-SET motif family protein 0.006 0.0326 0.1259
Loa Loa (eye worm) hypothetical protein 0.0048 0.0254 0.0968
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0023 0.0102 0.0358
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0063 0.0327
Loa Loa (eye worm) phosphofructokinase 0.0217 0.1274 0.5123
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.0334 0.0334
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0063 0.0327
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0048 0.0254 0.0238
Schistosoma mansoni biogenic amine receptor 0.0048 0.0254 0.0254
Echinococcus multilocularis neuropeptides capa receptor 0.0048 0.0254 0.0238
Schistosoma mansoni adenylate kinase 0.0049 0.0256 0.0256
Schistosoma mansoni adenylate kinase 0.0129 0.0741 0.0741
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0189 0.1106 0.1091
Schistosoma mansoni adenoreceptor 0.0048 0.0254 0.0254
Loa Loa (eye worm) hypothetical protein 0.0013 0.0043 0.0107
Echinococcus granulosus intermediate filament protein 0.0026 0.0121 0.0105
Schistosoma mansoni neuropeptide F-like receptor 0.0048 0.0254 0.0254
Leishmania major adenylate kinase, putative 0.0035 0.0176 0.1229
Echinococcus granulosus 3'partial|ectonucleoside triphosphate diphosphohydrolase 0.004 0.0202 0.0186
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0023 0.0102 0.0358
Echinococcus multilocularis neuropeptides capa receptor 0.0048 0.0254 0.0238
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0048 0.0254 0.0238
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0048 0.0129
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0048 0.0254 0.0254
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0038 0.0194 0.0194
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0048 0.0254 0.0238
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0036 0.018 0.1078
Loa Loa (eye worm) melatonin receptor type 1A 0.0048 0.0254 0.0968
Loa Loa (eye worm) hypothetical protein 0.0014 0.0048 0.0129
Brugia malayi hypothetical protein 0.0038 0.0194 0.0722
Brugia malayi hypothetical protein 0.0048 0.0254 0.0968
Loa Loa (eye worm) hypothetical protein 0.0048 0.0254 0.0968
Schistosoma mansoni P2X receptor subunit 0.1658 1 1
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0202 0.0714
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0074 0.0413 0.2977
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0023 0.0102 0.0358
Echinococcus granulosus axis inhibition protein axin 0.0038 0.0194 0.0178
Loa Loa (eye worm) hypothetical protein 0.0038 0.0194 0.0722
Mycobacterium tuberculosis Adenylate kinase Adk (ATP-AMP transphosphorylase) 0.0013 0.0043 0.0052
Echinococcus granulosus alpha 1A adrenergic receptor 0.0048 0.0254 0.0238
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0048 0.0254 0.0238
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0017 0.0063 0.022
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0102 0.0632
Trichomonas vaginalis adenosine/guanosine diphosphatase, putative 0.004 0.0202 0.0714
Loa Loa (eye worm) cytochrome P450 family protein 0.0023 0.0101 0.0345
Echinococcus multilocularis neuropeptide receptor 0.0048 0.0254 0.0238
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0048 0.0096
Schistosoma mansoni regulator of G protein signaling 0.0038 0.0194 0.0194
Echinococcus granulosus neuropeptide receptor A26 0.0495 0.2958 0.2947
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0023 0.0102 0.0782
Loa Loa (eye worm) hypothetical protein 0.0048 0.0254 0.0968
Loa Loa (eye worm) hypothetical protein 0.0036 0.018 0.0667
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0047 0.0126
Loa Loa (eye worm) histone methyltransferase 0.0011 0.0028 0.0047
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0017 0.0063 0.0327
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0023 0.0102 0.0358
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.002 0.0081 0.0269
Echinococcus multilocularis expressed protein 0.0033 0.016 0.0144
Brugia malayi Pre-SET motif family protein 0.0414 0.2471 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0048 0.0254 0.0254
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0023 0.0102 0.0358
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0023 0.0102 0.0632
Loa Loa (eye worm) hypothetical protein 0.0048 0.0254 0.0968
Echinococcus multilocularis ectonucleoside triphosphate diphosphohydrolase 0.042 0.2508 0.2496
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0059 0.0317 0.1205
Mycobacterium tuberculosis Putative ferredoxin reductase 0.011 0.0627 0.4772
Trichomonas vaginalis adenosine diphosphatase, putative 0.004 0.0202 0.0714
Brugia malayi putative neuropeptide receptor 0.0048 0.0254 0.0968
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0059 0.0317 0.7302
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A 0.0166 0.0966 0.387
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0048 0.0254 0.0238
Echinococcus granulosus regulator of G protein signaling 3 0.0038 0.0194 0.0178
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0048 0.0254 0.0238
Leishmania major adenylate kinase, putative 0.0016 0.0057 0.0271
Brugia malayi intermediate filament protein 0.0026 0.0121 0.0426
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.0018 0.0001
Brugia malayi hypothetical protein 0.0048 0.0254 0.0968
Trypanosoma cruzi nucleoside phosphatase, putative 0.004 0.0202 0.1432
Loa Loa (eye worm) hypothetical protein 0.0036 0.018 0.0667
Onchocerca volvulus 0.0048 0.0254 0.0745
Onchocerca volvulus 0.0048 0.0254 0.0745
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0023 0.0102 0.0102
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0194 0.0685
Trichomonas vaginalis adenosine diphosphatase, putative 0.004 0.0202 0.0714
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0032 0.0079
Echinococcus multilocularis p2X purinoceptor 4 0.1658 1 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0048 0.0254 0.0238
Schistosoma mansoni acetyl-CoA synthetase 0.0014 0.0048 0.0048
Echinococcus granulosus p2X purinoceptor 4 0.1658 1 1
Echinococcus multilocularis lamin 0.0026 0.0121 0.0105
Leishmania major adenylate kinase, putative 0.0049 0.0256 0.1869
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0023 0.0102 0.0358
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0023 0.0102 0.0085
Leishmania major ATP diphosphohydrolase 0.004 0.0202 0.1432
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0023 0.0102 0.0085
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0017 0.0063 0.0195
Trypanosoma cruzi trypanothione reductase, putative 0.0048 0.0254 0.1848
Brugia malayi glutathione reductase 0.0048 0.0254 0.0967
Toxoplasma gondii histone lysine methyltransferase SET1 0.0055 0.0296 0.2562
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0166 0.0966 0.0951
Brugia malayi AKH receptor 0.0048 0.0254 0.0968
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0023 0.0102 0.0358
Loa Loa (eye worm) hypothetical protein 0.0012 0.0036 0.008
Echinococcus granulosus beta-adrenergic receptor kinase 0.0038 0.0194 0.0178
Brugia malayi Bloom's syndrome protein homolog 0.0022 0.0093 0.0313
Loa Loa (eye worm) hypothetical protein 0.004 0.0202 0.0755
Echinococcus granulosus 6 phosphofructokinase 0.0217 0.1274 0.126
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0023 0.0102 0.0782
Trypanosoma cruzi nucleoside phosphatase, putative 0.004 0.0202 0.1432
Schistosoma mansoni lamin 0.0026 0.0121 0.0121
Schistosoma mansoni regulator of G protein signaling 0.0038 0.0194 0.0194
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0023 0.0102 0.0632
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0017 0.0063 0.0327
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0023 0.0102 0.0347
Leishmania major 4-coumarate:coa ligase-like protein 0.0048 0.0254 0.1848
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0189 0.1106 0.1091
Trichomonas vaginalis mercuric reductase, putative 0.0017 0.0063 0.0223
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0017 0.0063 0.0421
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0063 0.0327
Brugia malayi phosphofructokinase 0.0217 0.1274 0.5123
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0121 0.0426
Schistosoma mansoni hypothetical protein 0.0048 0.0254 0.0254
Loa Loa (eye worm) hypothetical protein 0.0048 0.0254 0.0968
Echinococcus multilocularis neuropeptide FF receptor 2 0.0048 0.0254 0.0238
Loa Loa (eye worm) G-protein coupled receptor 0.0048 0.0254 0.0968
Loa Loa (eye worm) hypothetical protein 0.006 0.0326 0.1259
Brugia malayi AMP-binding enzyme family protein 0.0048 0.0254 0.0967
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0038 0.0194 0.0722
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0014 0.0048 0.0127
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0014 0.005 0.0307
Loa Loa (eye worm) hypothetical protein 0.0048 0.0254 0.0967
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0048 0.0254 0.0254
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0023 0.0102 0.0102
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0023 0.0102 0.0358
Brugia malayi GnHR receptor homolog 0.0048 0.0254 0.0968
Loa Loa (eye worm) hypothetical protein 0.0038 0.0194 0.0722
Loa Loa (eye worm) hypothetical protein 0.0048 0.0254 0.0968
Trichomonas vaginalis set domain proteins, putative 0.0471 0.2817 1
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0023 0.0102 0.0358
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0168 0.1067
Brugia malayi regulator of G-protein signaling rgs-7 0.0038 0.0194 0.0722
Echinococcus granulosus somatostatin receptor 0.0048 0.0254 0.0238
Echinococcus multilocularis regulator of G protein signaling 3 0.0038 0.0194 0.0178
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0017 0.0063 0.0063
Giardia lamblia Adenylate kinase 0.0016 0.0057 0.0367
Loa Loa (eye worm) RecQ helicase 0.0022 0.0093 0.0313
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0023 0.0102 0.0782
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0048 0.0254 0.0238
Schistosoma mansoni serine/threonine protein kinase 0.0038 0.0194 0.0194
Trichomonas vaginalis DNA helicase recq, putative 0.0012 0.0032 0.0112
Loa Loa (eye worm) hypothetical protein 0.0036 0.018 0.0667
Loa Loa (eye worm) hypothetical protein 0.0048 0.0254 0.0968
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0023 0.0102 0.0102
Giardia lamblia Hypothetical protein 0.0023 0.0102 0.0782
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0011 0.0028 0.0011
Echinococcus granulosus fmrfamide receptor 0.0048 0.0254 0.0238
Loa Loa (eye worm) hypothetical protein 0.0048 0.0254 0.0968
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0102 0.0632
Loa Loa (eye worm) 6-phosphofructokinase 0.0217 0.1274 0.5123
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0023 0.0102 0.0358
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.011 0.0627 0.4772
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0014 0.0048 0.0129
Echinococcus multilocularis bloom syndrome protein 0.0022 0.0093 0.0077
Trypanosoma cruzi trypanothione reductase, putative 0.0017 0.0063 0.0327
Echinococcus granulosus neuropeptide s receptor 0.0495 0.2958 0.2947
Trypanosoma brucei nucleoside diphosphatase, putative 0.004 0.0202 0.1432
Brugia malayi PXA domain containing protein 0.0038 0.0194 0.0722
Schistosoma mansoni 6-phosphofructokinase 0.0217 0.1274 0.1274
Schistosoma mansoni histamine h1 receptor 0.0048 0.0254 0.0254
Echinococcus granulosus ectonucleoside triphosphate diphosphohydrolase 0.042 0.2508 0.2496
Plasmodium vivax 6-phosphofructokinase, putative 0.0059 0.0317 0.7364
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0014 0.0048 0.0096
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0194 0.0685
Echinococcus granulosus 7TM GPCR rhodopsin 0.0048 0.0254 0.0238
Echinococcus granulosus bloom syndrome protein 0.0022 0.0093 0.0077
Brugia malayi hypothetical protein 0.0048 0.0254 0.0968
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0023 0.0102 0.0102
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0048 0.0254 0.0968
Echinococcus multilocularis orexin receptor type 2 0.0048 0.0254 0.0238
Onchocerca volvulus 0.0048 0.0254 0.0745
Trypanosoma cruzi adenylate kinase, putative 0.0049 0.0256 0.1869
Trichomonas vaginalis phosphofructokinase, putative 0.0059 0.0317 0.1122
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0014 0.0048 0.0204
Echinococcus granulosus cpg binding protein 0.0029 0.0141 0.0125
Schistosoma mansoni amine GPCR 0.0048 0.0254 0.0254
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0038 0.0194 0.0194
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0023 0.0102 0.0632
Mycobacterium tuberculosis Probable reductase 0.011 0.0627 0.4772
Echinococcus multilocularis p2X purinoceptor 4 0.1658 1 1
Loa Loa (eye worm) hypothetical protein 0.0189 0.1106 0.4437
Echinococcus multilocularis neuropeptide Y receptor 0.0048 0.0254 0.0238
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0023 0.0102 0.0347
Loa Loa (eye worm) hypothetical protein 0.0048 0.0254 0.0968
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0048 0.0254 0.0238
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0023 0.0102 0.0632
Brugia malayi ORL1-like opioid receptor 0.0048 0.0254 0.0968
Plasmodium vivax acyl-CoA synthetase, putative 0.0036 0.018 0.362
Brugia malayi hypothetical protein 0.0048 0.0254 0.0968
Echinococcus granulosus G protein coupled receptor 139 0.0048 0.0254 0.0238
Echinococcus multilocularis neuropeptide s receptor 0.0495 0.2958 0.2947
Loa Loa (eye worm) hypothetical protein 0.0048 0.0254 0.0968
Onchocerca volvulus 0.0048 0.0254 0.0745
Loa Loa (eye worm) hypothetical protein 0.0048 0.0254 0.0968
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0017 0.0063 0.0431
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0014 0.0048 0.0096
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0023 0.0102 0.0782
Plasmodium vivax phosphodiesterase gamma, putative 0.0023 0.0102 0.1468
Brugia malayi Dopamine receptor protein 1 0.0048 0.0254 0.0968
Echinococcus granulosus regulator of G protein signaling 3 0.0038 0.0194 0.0178
Echinococcus granulosus Regulator of G protein signaling 20 0.0038 0.0194 0.0178
Echinococcus granulosus allatostatin A receptor 0.0048 0.0254 0.0238
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0102 0.0632
Trichomonas vaginalis phosphofructokinase, putative 0.0217 0.1274 0.4521
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0131 0.0468
Echinococcus multilocularis rhodopsin orphan GPCR 0.0048 0.0254 0.0238
Echinococcus multilocularis dro:myosuppressin receptor 0.0048 0.0254 0.0238
Brugia malayi 6-phosphofructokinase 0.0217 0.1274 0.5123
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.006 0.0326 0.0309
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0059 0.0317 0.2093
Trypanosoma cruzi adenylate kinase 1 0.0016 0.0057 0.0271
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.006 0.0326 0.2837
Trypanosoma cruzi adenylate kinase, putative 0.0049 0.0256 0.1869
Brugia malayi Regulator of G protein signaling domain containing protein 0.0038 0.0194 0.0722
Trichomonas vaginalis antibiotic synthetase, putative 0.0014 0.0048 0.0168
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0023 0.0102 0.0085
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0014 0.0048 0.0096
Leishmania major hypothetical protein, conserved 0.0023 0.0102 0.0632
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0048 0.0254 0.0238
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0122 0.0701 0.537
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0102 0.0632
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0048 0.0254 0.1679
Leishmania major 4-coumarate:coa ligase-like protein 0.0048 0.0254 0.1848
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0023 0.0102 0.0358
Loa Loa (eye worm) hypothetical protein 0.0023 0.0102 0.0347
Echinococcus granulosus neuropeptides capa receptor 0.0048 0.0254 0.0238
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0009 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0012 0.0036 0.008
Echinococcus multilocularis serotonin receptor 0.0048 0.0254 0.0238
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0014 0.0048 0.0096
Loa Loa (eye worm) hypothetical protein 0.0036 0.018 0.0667
Loa Loa (eye worm) glutathione reductase 0.0048 0.0254 0.0967
Plasmodium falciparum acyl-CoA synthetase 0.0036 0.018 0.0657
Schistosoma mansoni cpg binding protein 0.0029 0.0141 0.0141
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.002 0.0081 0.0263
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0038 0.0194 0.0194
Mycobacterium ulcerans epimerase 0.002 0.0081 0.0269
Toxoplasma gondii peptidylprolyl isomerase 0.0032 0.0155 0.1273
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0033 0.016 0.0584
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0023 0.0102 0.0342
Loa Loa (eye worm) hypothetical protein 0.0036 0.018 0.0667
Onchocerca volvulus 0.0048 0.0254 0.0745
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0023 0.0102 0.0347
Onchocerca volvulus 0.0048 0.0254 0.0745
Trichomonas vaginalis glutathione reductase, putative 0.0017 0.0063 0.0223
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0023 0.0102 0.0632
Loa Loa (eye worm) neuropeptide F receptor 0.0048 0.0254 0.0968
Echinococcus granulosus tachykinin peptides receptor 99D 0.0048 0.0254 0.0238
Echinococcus granulosus g protein coupled receptor 0.0048 0.0254 0.0238
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0048 0.0254 0.1679
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0014 0.0048 0.0129
Plasmodium vivax glutathione reductase, putative 0.0048 0.0254 0.5635
Loa Loa (eye worm) hypothetical protein 0.0026 0.0118 0.0414
Loa Loa (eye worm) hypothetical protein 0.0048 0.0254 0.0968
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0038 0.0194 0.0178
Loa Loa (eye worm) neuropeptide F receptor 0.0048 0.0254 0.0968
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.0093 0.0329
Loa Loa (eye worm) hypothetical protein 0.0048 0.0254 0.0968
Echinococcus multilocularis neuropeptide receptor 0.0048 0.0254 0.0238
Onchocerca volvulus 0.0026 0.0121 0.0264
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0023 0.0102 0.0358
Toxoplasma gondii adenylate kinase, putative 0.0049 0.0256 0.2203
Plasmodium vivax nucleoside-diphosphatase mig-23, putative 0.004 0.0202 0.4211
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0047 0.0126
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.0001 0.000000000079038
Echinococcus multilocularis Regulator of G protein signaling 20 0.0038 0.0194 0.0178
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0015 0.0051 0.0079
Brugia malayi Dopamine receptor protein 2 0.0048 0.0254 0.0968
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0023 0.0102 0.0782
Trichomonas vaginalis phosphofructokinase, putative 0.0217 0.1274 0.4521
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0023 0.0102 0.0347
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0023 0.0102 0.0358
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.016 0.0565
Echinococcus granulosus tm gpcr rhodopsin 0.0048 0.0254 0.0238
Plasmodium falciparum glutathione reductase 0.0017 0.0063 0.0188
Loa Loa (eye worm) hypothetical protein 0.0014 0.0048 0.0129
Loa Loa (eye worm) hypothetical protein 0.0048 0.0254 0.0968
Schistosoma mansoni P2X receptor subunit 0.0822 0.494 0.494
Giardia lamblia hypothetical protein 0.0023 0.0102 0.0782
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0032 0.0155 0.106
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0032 0.0079
Entamoeba histolytica phosphofructokinase, putative 0.0217 0.1274 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0048 0.0254 0.0238
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0048 0.0254 0.0968
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0023 0.0102 0.0782
Schistosoma mansoni neuropeptide receptor 0.0048 0.0254 0.0254
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0074 0.0413 1
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0038 0.0194 0.0685
Entamoeba histolytica adenylate kinase 0.0016 0.0057 0.0194
Schistosoma mansoni P2X receptor subunit 0.1658 1 1
Onchocerca volvulus 0.0028 0.0131 0.0301
Mycobacterium ulcerans hypothetical protein 0.0048 0.0254 0.1679
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0063 0.0327
Brugia malayi neuropeptide F receptor 0.0048 0.0254 0.0968
Trypanosoma brucei adenylate kinase, putative 0.0016 0.0057 0.0271
Entamoeba histolytica acyl-coA synthetase, putative 0.0048 0.0254 0.1784
Loa Loa (eye worm) hypothetical protein 0.002 0.0081 0.0263
Echinococcus multilocularis rhodopsin orphan GPCR 0.0048 0.0254 0.0238
Schistosoma mansoni amine GPCR 0.0048 0.0254 0.0254
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0048 0.0254 0.1679
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0414 0.2471 1
Schistosoma mansoni regulator of G protein signaling 0.0038 0.0194 0.0194
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0023 0.0102 0.0085
Echinococcus granulosus g-protein coupled receptor 0.0048 0.0254 0.0238
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0059 0.0317 0.2291
Echinococcus granulosus rhodopsin orphan GPCR 0.0048 0.0254 0.0238
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0014 0.0048 0.0204
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0048 0.0254 0.0254
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0009 0.0018 0.0001
Echinococcus granulosus lamin 0.0026 0.0121 0.0105
Toxoplasma gondii endonuclease IV APN 0.0074 0.0413 0.3641
Echinococcus granulosus histone lysine methyltransferase setb 0.006 0.0326 0.0309
Schistosoma mansoni P2X receptor subunit 0.0822 0.494 0.494
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0011 0.0028 0.0011
Onchocerca volvulus 0.0471 0.2817 1
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.006 0.0326 0.0326
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0023 0.0102 0.0347
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0006 0.0001 0.000000000079038
Schistosoma mansoni adenosine diphosphatase 0.004 0.0202 0.0202
Onchocerca volvulus 0.0048 0.0254 0.0745
Echinococcus multilocularis fmrfamide receptor 0.0048 0.0254 0.0238
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0048 0.0254 0.0254
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0217 0.1274 1
Trichomonas vaginalis phosphofructokinase, putative 0.0059 0.0317 0.1122
Trypanosoma cruzi adenylate kinase, putative 0.0016 0.0057 0.0271
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0048 0.0254 0.0968
Schistosoma mansoni neuropeptide receptor 0.0048 0.0254 0.0254
Echinococcus granulosus axis inhibition protein axin 0.0038 0.0194 0.0178
Mycobacterium ulcerans 6-phosphofructokinase 0.0217 0.1274 1
Echinococcus granulosus dro:myosuppressin receptor 0.0048 0.0254 0.0238
Echinococcus granulosus rhodopsin orphan GPCR 0.0048 0.0254 0.0238
Echinococcus multilocularis rhodopsin orphan GPCR 0.0048 0.0254 0.0238
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0023 0.0102 0.0358
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0121 0.0426
Trypanosoma brucei adenylate kinase, putative 0.0049 0.0256 0.1869
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0036 0.018 0.1164
Schistosoma mansoni myosin xvIII 0.0048 0.0254 0.0254
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0059 0.0317 0.2758
Echinococcus multilocularis axis inhibition protein axin 0.0038 0.0194 0.0178
Echinococcus multilocularis sex peptide receptor 0.0048 0.0254 0.0238
Echinococcus granulosus neuropeptide Y receptor 0.0048 0.0254 0.0238
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0009 0.0017 0.00000000022575
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0048 0.0254 0.0254
Echinococcus granulosus orexin receptor type 2 0.0048 0.0254 0.0238
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0023 0.0102 0.0358
Echinococcus granulosus adenylate kinase 0.0016 0.0057 0.004
Loa Loa (eye worm) TYRA-2 protein 0.0048 0.0254 0.0968
Giardia lamblia NADH oxidase lateral transfer candidate 0.0017 0.0063 0.0431
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0122 0.0701 0.537
Schistosoma mansoni opsin-like receptor 0.0048 0.0254 0.0254
Brugia malayi G-protein coupled receptor 0.0048 0.0254 0.0968
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.011 0.0627 0.4721
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0048 0.0096
Entamoeba histolytica phosphofructokinase, putative 0.0217 0.1274 1
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0048 0.0254 0.0968
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0039 0.0023
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0023 0.0102 0.0358
Schistosoma mansoni lamin 0.0026 0.0121 0.0121
Onchocerca volvulus 0.0048 0.0254 0.0745
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0048 0.0129
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0012 0.0037 0.0082
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0017 0.0063 0.0327
Echinococcus multilocularis regulator of G protein signaling 0.0038 0.0194 0.0178
Mycobacterium ulcerans acyl-CoA synthetase 0.0048 0.0254 0.1679
Loa Loa (eye worm) PXA domain-containing protein 0.0038 0.0194 0.0722
Toxoplasma gondii NTPase II 0.004 0.0202 0.1701
Loa Loa (eye worm) hypothetical protein 0.0023 0.0102 0.0347
Plasmodium falciparum glutathione reductase 0.0048 0.0254 0.0952
Trichomonas vaginalis adenosine diphosphatase, putative 0.004 0.0202 0.0714
Loa Loa (eye worm) hypothetical protein 0.0048 0.0254 0.0968
Echinococcus multilocularis beta adrenergic receptor kinase 0.0038 0.0194 0.0178
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0048 0.0254 0.0254
Loa Loa (eye worm) hypothetical protein 0.0048 0.0254 0.0968
Loa Loa (eye worm) hypothetical protein 0.0048 0.0254 0.0968
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0048 0.0254 0.0968
Schistosoma mansoni neuropeptide f receptor 76f 0.0048 0.0254 0.0254
Plasmodium falciparum nucleoside-diphosphatase, putative 0.004 0.0202 0.0743
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0017 0.0063 1
Brugia malayi Melatonin receptor type 1A 0.0048 0.0254 0.0968
Loa Loa (eye worm) hypothetical protein 0.0048 0.0254 0.0968
Treponema pallidum adenylate kinase (adk) 0.0049 0.0256 0.1594
Loa Loa (eye worm) hypothetical protein 0.0048 0.0254 0.0968
Trichomonas vaginalis phosphofructokinase, putative 0.0059 0.0317 0.1122
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0217 0.1274 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.0121 0.0426
Echinococcus multilocularis adenylate kinase 2, mitochondrial 0.0049 0.0256 0.024
Mycobacterium ulcerans adenylate kinase 0.0016 0.0057 0.0069
Echinococcus multilocularis rhodopsin orphan GPCR 0.0048 0.0254 0.0238
Echinococcus granulosus adenylate kinase 2 mitochondrial 0.0049 0.0256 0.024
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0189 0.1106 0.1091
Echinococcus multilocularis 6 phosphofructokinase 0.0217 0.1274 0.126
Loa Loa (eye worm) hypothetical protein 0.0048 0.0254 0.0968
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0194 0.0685
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0023 0.0102 0.0782
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0017 0.0063 0.0125
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0023 0.0102 0.0358
Mycobacterium ulcerans endonuclease IV 0.0074 0.0413 0.2977
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0023 0.0102 0.0358
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0189 0.1106 1
Brugia malayi G protein-coupled receptor F59B2.13 0.0048 0.0254 0.0968
Loa Loa (eye worm) hypothetical protein 0.0038 0.0194 0.0722
Brugia malayi CXXC zinc finger family protein 0.0028 0.0131 0.0468
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.0001 0.000000000079038
Echinococcus granulosus 7tm_1 domain containing protein 0.0048 0.0254 0.0238
Brugia malayi neuropeptide F receptor 0.0048 0.0254 0.0968
Brugia malayi hypothetical protein 0.0048 0.0254 0.0968
Echinococcus granulosus g protein coupled receptor 0.0048 0.0254 0.0238
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0048 0.0096
Plasmodium vivax SET domain protein, putative 0.006 0.0326 0.7601
Loa Loa (eye worm) hypothetical protein 0.0038 0.0194 0.0722
Echinococcus multilocularis G-protein coupled receptor, putative 0.0048 0.0254 0.0238
Echinococcus multilocularis neuropeptide Y receptor 0.0048 0.0254 0.0238
Echinococcus multilocularis allatostatin A receptor 0.0048 0.0254 0.0238
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0023 0.0102 0.0358
Toxoplasma gondii phosphofructokinase PFKII 0.0059 0.0317 0.2758
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0023 0.0102 0.0632
Mycobacterium ulcerans acyl-CoA synthetase 0.0048 0.0254 0.1679
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.0001 0.000000000079038
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0023 0.0102 0.0358
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0048 0.0254 0.0238
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0023 0.0102 0.0782
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0023 0.0102 0.0358
Brugia malayi Thioredoxin reductase 0.0048 0.0254 0.0967
Brugia malayi Serotonin receptor 0.0048 0.0254 0.0968
Echinococcus multilocularis thioredoxin glutathione reductase 0.0048 0.0254 0.0238
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0081 0.0362
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0023 0.0102 0.0782
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0014 0.0048 0.0126
Toxoplasma gondii thioredoxin reductase 0.0048 0.0254 0.2178
Onchocerca volvulus Adenylate kinase isoenzyme 1 homolog 0.0016 0.0057 0.003
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0023 0.0102 0.0342
Trichomonas vaginalis phosphofructokinase, putative 0.0217 0.1274 0.4521
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0014 0.0048 0.0204
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0014 0.0048 0.0096
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0048 0.0254 0.0254
Loa Loa (eye worm) hypothetical protein 0.0023 0.0102 0.0347
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0032 0.0155 0.0989
Schistosoma mansoni guanosine-diphosphatase 0.004 0.0202 0.0202
Brugia malayi hypothetical protein 0.0048 0.0254 0.0968
Schistosoma mansoni neuropeptide receptor 0.0048 0.0254 0.0254
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0023 0.0102 0.0342
Toxoplasma gondii GDA1/CD39 (nucleoside phosphatase) family protein 0.004 0.0202 0.1701
Onchocerca volvulus 0.0048 0.0254 0.0745
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0017 0.0063 0.0188
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0048 0.0254 0.0254
Trichomonas vaginalis antibiotic synthetase, putative 0.0014 0.0048 0.0168
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0023 0.0102 0.0358
Plasmodium vivax adenylate kinase 2, putative 0.0049 0.0256 0.5708
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0023 0.0102 0.0782
Echinococcus granulosus f box and leucine rich repeat protein 0.0013 0.0043 0.0026
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0048 0.0254 0.0254
Plasmodium vivax 6-phosphofructokinase, putative 0.0059 0.0317 0.7364
Schistosoma mansoni intermediate filament proteins 0.0026 0.0121 0.0121
Trypanosoma brucei trypanothione reductase 0.0048 0.0254 0.1848
Schistosoma mansoni growth hormone secretagogue receptor 0.0048 0.0254 0.0254
Echinococcus granulosus neuropeptide receptor 0.0048 0.0254 0.0238
Schistosoma mansoni adenylate kinase 0.0049 0.0256 0.0256
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0048 0.0254 0.0238
Echinococcus granulosus lamin dm0 0.0026 0.0121 0.0105
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0048 0.0254 0.0745
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0023 0.0102 0.0358
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0048 0.0254 0.0254
Schistosoma mansoni alpha-1 adrenergic receptor 0.0048 0.0254 0.0254
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0017 0.0063 0.0327
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0023 0.0102 0.0358
Schistosoma mansoni hypothetical protein 0.0048 0.0254 0.0254
Schistosoma mansoni regulator of G protein signaling 0.0038 0.0194 0.0194
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0023 0.0102 0.0358
Schistosoma mansoni opsin-like receptor 0.0048 0.0254 0.0254
Brugia malayi 6-phosphofructokinase 0.0217 0.1274 0.5123
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0023 0.0102 0.0782
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0023 0.0102 0.0085
Echinococcus multilocularis G protein coupled receptor 139 0.0048 0.0254 0.0238
Loa Loa (eye worm) hypothetical protein 0.0048 0.0254 0.0968
Brugia malayi putative neuropeptide receptor NPR1 0.0048 0.0254 0.0968
Echinococcus granulosus neuropeptide FF receptor 2 0.0048 0.0254 0.0238
Brugia malayi AMP-binding enzyme family protein 0.0048 0.0254 0.0967
Echinococcus multilocularis f box and leucine rich repeat protein 0.0013 0.0043 0.0026
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0102 0.0632
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0048 0.0129
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0048 0.0254 0.0254
Loa Loa (eye worm) hypothetical protein 0.0048 0.0254 0.0968
Loa Loa (eye worm) hypothetical protein 0.0038 0.0194 0.0722
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0023 0.0102 0.0102
Loa Loa (eye worm) hypothetical protein 0.0048 0.0254 0.0968
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0059 0.0317 0.2758
Echinococcus multilocularis lamin dm0 0.0026 0.0121 0.0105
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0012 0.0037 0.0082
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0038 0.0194 0.0178
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0023 0.0102 0.0085
Echinococcus multilocularis ectonucleoside triphosphate diphosphohydrolase 0.042 0.2508 0.2496
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0023 0.0102 0.0632
Echinococcus granulosus g protein coupled receptor 0.0048 0.0254 0.0238
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0155 0.106
Brugia malayi RE15519p 0.0048 0.0254 0.0968
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0023 0.0102 0.0782
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0102 0.0358
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0048 0.0096
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0217 0.1274 1
Onchocerca volvulus 0.0048 0.0254 0.0745
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0014 0.0048 0.0204
Brugia malayi hypothetical protein 0.0048 0.0254 0.0968
Brugia malayi Serotonin receptor 0.0048 0.0254 0.0968
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0023 0.0102 0.0347
Onchocerca volvulus 0.0048 0.0254 0.0745
Loa Loa (eye worm) hypothetical protein 0.0048 0.0254 0.0968
Schistosoma mansoni biogenic amine (5HT) receptor 0.0048 0.0254 0.0254
Loa Loa (eye worm) hypothetical protein 0.0048 0.0254 0.0968
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0063 0.0327
Toxoplasma gondii Nucleoside-diphosphatase 0.004 0.0202 0.1701
Entamoeba histolytica hypothetical protein 0.0038 0.0194 0.13
Loa Loa (eye worm) thioredoxin reductase 0.0048 0.0254 0.0967
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0048 0.0254 0.0238
Echinococcus multilocularis rhodopsin orphan GPCR 0.0048 0.0254 0.0238
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0023 0.0102 0.0342
Onchocerca volvulus 0.0048 0.0254 0.0743
Onchocerca volvulus 0.0026 0.0121 0.0264
Loa Loa (eye worm) hypothetical protein 0.0016 0.0057 0.0163
Plasmodium falciparum thioredoxin reductase 0.0048 0.0254 0.0952
Loa Loa (eye worm) hypothetical protein 0.0048 0.0254 0.0968
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0048 0.0254 0.1758
Echinococcus granulosus expressed protein 0.0744 0.4466 0.4457
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0023 0.0102 0.0358
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0023 0.0102 0.0085
Toxoplasma gondii propionate-CoA ligase 0.0014 0.0048 0.029
Toxoplasma gondii GDA1/CD39 (nucleoside phosphatase) family protein 0.004 0.0202 0.1701
Schistosoma mansoni DNA helicase recq5 0.0009 0.0017 0.0017
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0168 0.1067
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0048 0.0254 0.1679
Mycobacterium leprae conserved hypothetical protein 0.002 0.0081 0.0269
Loa Loa (eye worm) hypothetical protein 0.0016 0.0057 0.0163
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0023 0.0102 0.0782
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0048 0.0254 0.0238
Loa Loa (eye worm) hypothetical protein 0.0048 0.0254 0.0968
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.0001 0.000000000079038
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0202 0.0714
Schistosoma mansoni cpg binding protein 0.0028 0.0131 0.0131
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0048 0.0254 0.1679
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0023 0.0102 0.1468
Trypanosoma brucei nucleoside phosphatase, putative 0.004 0.0202 0.1432
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.0018 0.0001
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0189 0.1106 0.1106
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0048 0.0254 0.0254
Echinococcus multilocularis adenylate kinase 0.0016 0.0057 0.004
Echinococcus granulosus serotonin receptor 0.0048 0.0254 0.0238
Leishmania major adenylate kinase 2 0.0035 0.0176 0.1229
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0048 0.0254 0.0254
Echinococcus multilocularis g protein coupled receptor 0.0048 0.0254 0.0238
Loa Loa (eye worm) 6-phosphofructokinase 0.0217 0.1274 0.5123
Toxoplasma gondii GDA1/CD39 (nucleoside phosphatase) family protein 0.004 0.0202 0.1701
Echinococcus multilocularis ectonucleoside triphosphate diphosphohydrolase 0.004 0.0202 0.0186
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0048 0.0129
Leishmania major acetyl-CoA synthetase, putative 0.0014 0.0048 0.0204
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0023 0.0102 0.0085
Loa Loa (eye worm) hypothetical protein 0.0048 0.0254 0.0968
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0023 0.0102 0.0358
Loa Loa (eye worm) hypothetical protein 0.0048 0.0254 0.0968
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0048 0.0254 0.0238
Brugia malayi Cytochrome P450 family protein 0.0023 0.0101 0.0345
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0023 0.0102 0.1468
Echinococcus multilocularis rhodopsin orphan GPCR 0.0048 0.0254 0.0238
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.011 0.0627 0.4772
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0048 0.0254 0.0968
Schistosoma mansoni hypothetical protein 0.0048 0.0254 0.0254
Echinococcus multilocularis regulator of G protein signaling 3 0.0038 0.0194 0.0178
Toxoplasma gondii NADPH-glutathione reductase 0.0017 0.0063 0.0431
Loa Loa (eye worm) hypothetical protein 0.0048 0.0254 0.0968
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0032 0.0079
Chlamydia trachomatis endonuclease IV 0.0074 0.0413 1
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0102 0.0632
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0023 0.0102 0.0782
Echinococcus multilocularis musashi 0.0026 0.0121 0.0105
Echinococcus granulosus ectonucleoside triphosphate diphosphohydrolase 0.004 0.0202 0.0186
Schistosoma mansoni amine GPCR 0.0048 0.0254 0.0254
Brugia malayi F/Y-rich N-terminus family protein 0.0011 0.0027 0.0044
Mycobacterium tuberculosis Probable oxidoreductase 0.0122 0.0701 0.537
Trichomonas vaginalis guanosine-diphosphatase, putative 0.004 0.0202 0.0714
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0017 0.0063 0.0421
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0063 0.0327
Trichomonas vaginalis phosphofructokinase, putative 0.0217 0.1274 0.4521
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0014 0.0048 0.0204
Echinococcus granulosus sex peptide receptor 0.0048 0.0254 0.0238
Echinococcus granulosus tm gpcr rhodopsin 0.0048 0.0254 0.0238
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0023 0.0102 0.0358
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0023 0.0102 0.0632
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0048 0.0254 0.0968
Brugia malayi follicle stimulating hormone receptor 0.0048 0.0254 0.0968
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0014 0.0048 0.0096
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0006 0.0001 0.000000000079038
Schistosoma mansoni z-protein (S1r protein) 0.0038 0.0194 0.0194
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0102 0.0358
Trichomonas vaginalis phosphofructokinase, putative 0.0059 0.0317 0.1122
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0023 0.0102 0.0358
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0102 0.0632
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0057 0.0309 0.0293
Plasmodium falciparum phosphodiesterase delta, putative 0.0023 0.0102 0.0342
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0189 0.1106 1
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0189 0.1106 0.1091
Schistosoma mansoni biogenic amine receptor 0.0048 0.0254 0.0254
Onchocerca volvulus 0.0048 0.0254 0.0745
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0017 0.0063 0.0125
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0014 0.0048 0.0129
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0166 0.0966 0.0951
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0023 0.0102 0.0632
Schistosoma mansoni amine GPCR 0.0048 0.0254 0.0254
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0023 0.0102 0.0358
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0121 0.0426
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0023 0.0102 0.0358
Brugia malayi Regulator of G protein signaling domain containing protein 0.0038 0.0194 0.0722
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0023 0.0102 0.0358
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0048 0.0254 0.0254
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0036 0.018 0.347
Leishmania major nucleoside phosphatase, putative,guanosine diphosphatase, putative 0.004 0.0202 0.1432
Schistosoma mansoni hypothetical protein 0.0048 0.0254 0.0254
Echinococcus granulosus neuropeptide receptor 0.0048 0.0254 0.0238
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0102 0.0358
Schistosoma mansoni DNA helicase recq1 0.0009 0.0017 0.0017
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0023 0.0102 0.0358
Leishmania major hypothetical protein, conserved 0.0023 0.0102 0.0632
Schistosoma mansoni axis inhibition protein axin 0.0038 0.0194 0.0194
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0048 0.0254 0.0968
Leishmania major acetyl-CoA synthetase, putative 0.0014 0.0048 0.0204
Mycobacterium tuberculosis Probable dehydrogenase 0.011 0.0627 0.4772
Trypanosoma cruzi adenylate kinase 2 0.0035 0.0176 0.1229
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0023 0.0102 0.0085
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0023 0.0102 0.0632
Plasmodium falciparum phosphodiesterase gamma, putative 0.0023 0.0102 0.0342
Brugia malayi G-protein coupled receptor 0.0048 0.0254 0.0968
Loa Loa (eye worm) hypothetical protein 0.0048 0.0254 0.0968
Trichomonas vaginalis rotamase, putative 0.0033 0.016 0.0565
Brugia malayi sulfakinin receptor protein 0.0048 0.0254 0.0968
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0023 0.0102 0.0358
Onchocerca volvulus 0.0048 0.0254 0.0745
Echinococcus granulosus p2X purinoceptor 4 0.1658 1 1
Loa Loa (eye worm) hypothetical protein 0.0048 0.0254 0.0968
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0017 0.0063 0.0125
Entamoeba histolytica acyl-CoA synthetase, putative 0.0048 0.0254 0.1784
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0032 0.0155 0.106
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.006 0.0326 0.0326
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0168 0.1067
Echinococcus granulosus mixed lineage leukemia protein mll 0.0009 0.0018 0.0001
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0122 0.0701 0.5326
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0048 0.0254 0.0238
Brugia malayi G protein-coupled receptor 0.0048 0.0254 0.0968
Echinococcus multilocularis expressed protein 0.0744 0.4466 0.4457
Loa Loa (eye worm) oxidoreductase 0.0014 0.0048 0.0129
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0017 0.0063 0.0188
Echinococcus granulosus regulator of G protein signaling 7 0.0038 0.0194 0.0178
Schistosoma mansoni biogenic amine (5HT) receptor 0.0048 0.0254 0.0254
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0063 0.0327
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0038 0.0194 0.0722
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0023 0.0102 0.0102
Entamoeba histolytica hypothetical protein 0.0038 0.0194 0.13
Loa Loa (eye worm) hypothetical protein 0.0038 0.0194 0.0722
Plasmodium vivax thioredoxin reductase, putative 0.0048 0.0254 0.5635
Onchocerca volvulus Neuropeptide F receptor homolog 0.0048 0.0254 0.0745
Wolbachia endosymbiont of Brugia malayi adenylate kinase 0.0016 0.0057 0.83
Schistosoma mansoni regulator of G protein signaling 0.0038 0.0194 0.0194
Echinococcus multilocularis somatostatin receptor 0.0048 0.0254 0.0238
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0194 0.0685
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0023 0.0102 0.0358
Trichomonas vaginalis phosphofructokinase, putative 0.0059 0.0317 0.1122
Echinococcus granulosus tm gpcr rhodopsin 0.0048 0.0254 0.0238
Brugia malayi Dopamine receptor 0.0048 0.0254 0.0968
Schistosoma mansoni blooms syndrome DNA helicase 0.0017 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.0048 0.0254 0.0968
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0048 0.0254 0.1758
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.006 0.0326 0.0326
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0023 0.0102 0.0102
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.0001 0.000000000079038
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0048 0.0254 0.1679
Trypanosoma brucei adenylate kinase, putative 0.0035 0.0176 0.1229
Trichomonas vaginalis adenosine diphosphatase, putative 0.004 0.0202 0.0714
Onchocerca volvulus 0.006 0.0326 0.1002
Schistosoma mansoni cpg binding protein 0.0029 0.0141 0.0141
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0194 0.0685
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0014 0.0048 0.0096
Entamoeba histolytica hypothetical protein 0.0038 0.0194 0.13
Trichomonas vaginalis rotamase, putative 0.0032 0.0155 0.0548
Echinococcus granulosus regulator of G protein signaling 7 0.0038 0.0194 0.0178
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0048 0.0254 0.0238
Echinococcus multilocularis p2X purinoceptor 4 0.1658 1 1
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0217 0.1274 1
Leishmania major cAMP-specific phosphodiesterase, putative 0.0023 0.0102 0.0632
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0063 0.0327
Echinococcus granulosus rhodopsin orphan GPCR 0.0048 0.0254 0.0238
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0014 0.0048 0.029
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0166 0.0966 0.387
Loa Loa (eye worm) hypothetical protein 0.0048 0.0254 0.0968
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0217 0.1274 1
Leishmania major ATP-dependent phosphofructokinase 0.0217 0.1274 1
Loa Loa (eye worm) hypothetical protein 0.0048 0.0254 0.0968
Brugia malayi hypothetical protein 0.0048 0.0254 0.0968
Entamoeba histolytica acyl-CoA synthetase, putative 0.0048 0.0254 0.1784
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0059 0.0317 0.1122
Loa Loa (eye worm) hypothetical protein 0.0048 0.0254 0.0968
Brugia malayi adenylate kinase isoenzyme 1 0.0016 0.0057 0.0163
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0039 0.0023
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0023 0.0102 0.0782
Brugia malayi Tachykinin-like peptides receptor 99D 0.0048 0.0254 0.0968
Echinococcus granulosus biogenic amine 5HT receptor 0.0048 0.0254 0.0238
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0023 0.0102 0.0782
Echinococcus multilocularis axis inhibition protein axin 0.0038 0.0194 0.0178
Onchocerca volvulus 0.0048 0.0254 0.0745
Schistosoma mansoni serine/threonine protein kinase 0.0038 0.0194 0.0194
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0023 0.0102 0.0632
Brugia malayi A-kinase anchor protein 10, precursor 0.0038 0.0194 0.0722
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0048 0.0254 0.0254
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0048 0.0254 0.0238
Echinococcus granulosus rhodopsin orphan GPCR 0.0048 0.0254 0.0238
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0014 0.0048 0.0204
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0023 0.0102 0.0358
Brugia malayi Nucleoside-diphosphatase mig-23 0.004 0.0202 0.0755
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.006 0.0326 0.0326
Schistosoma mansoni rotamase 0.0033 0.016 0.016
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0023 0.0102 0.0102
Onchocerca volvulus 0.0048 0.0254 0.0745
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.002 0.0081 0.0119
Entamoeba histolytica phosphofructokinase, putative 0.0217 0.1274 1
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0014 0.0048 0.0032
Echinococcus multilocularis cpg binding protein 0.0029 0.0141 0.0125
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0023 0.0102 0.0085
Echinococcus granulosus neuropeptide Y receptor 0.0048 0.0254 0.0238
Echinococcus multilocularis serotonin receptor 0.0048 0.0254 0.0238
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0023 0.0102 0.0632
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0017 0.0063 0.0191
Loa Loa (eye worm) hypothetical protein 0.0048 0.0254 0.0968
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0168 0.1067
Mycobacterium ulcerans acyl-CoA synthetase 0.0048 0.0254 0.1679
Schistosoma mansoni neuropeptide F-like receptor 0.0048 0.0254 0.0254
Trichomonas vaginalis NADH dehydrogenase 51 kDa subunit, putative 0.0049 0.0256 0.0908
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0023 0.0102 0.0085
Echinococcus granulosus rhodopsin orphan GPCR 0.0048 0.0254 0.0238
Loa Loa (eye worm) G-protein coupled receptor 0.0048 0.0254 0.0968
Schistosoma mansoni 6-phosphofructokinase 0.0217 0.1274 0.1274
Loa Loa (eye worm) hypothetical protein 0.0048 0.0254 0.0967
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0023 0.0102 0.0085
Loa Loa (eye worm) hypothetical protein 0.0048 0.0254 0.0968
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0023 0.0102 0.0358
Schistosoma mansoni amine GPCR 0.0048 0.0254 0.0254
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0023 0.0102 0.0102
Echinococcus multilocularis regulator of G protein signaling 7 0.0038 0.0194 0.0178
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0048 0.0254 0.0238
Loa Loa (eye worm) hypothetical protein 0.0048 0.0254 0.0968
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0048 0.0254 0.0254
Echinococcus multilocularis regulator of G protein signaling 7 0.0038 0.0194 0.0178
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0059 0.0317 0.1205
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0017 0.0063 1
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0023 0.0102 0.0102
Echinococcus multilocularis fmrfamide receptor 0.0048 0.0254 0.0238
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0023 0.0102 0.0358
Brugia malayi AMP-binding enzyme family protein 0.0048 0.0254 0.0967
Toxoplasma gondii adenylate kinase 0.0016 0.0057 0.0367
Loa Loa (eye worm) hypothetical protein 0.0017 0.0067 0.0205
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0023 0.0102 0.1468
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0033 0.016 0.0584
Loa Loa (eye worm) hypothetical protein 0.0048 0.0254 0.0967
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0059 0.0317 0.7302
Schistosoma mansoni axis inhibition protein axin 0.0038 0.0194 0.0194
Trichomonas vaginalis guanosine-diphosphatase, putative 0.004 0.0202 0.0714
Loa Loa (eye worm) hypothetical protein 0.0048 0.0254 0.0968
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0048 0.0254 0.0254
Leishmania major 4-coumarate:coa ligase-like protein 0.0048 0.0254 0.1848
Leishmania major trypanothione reductase 0.0048 0.0254 0.1848
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0014 0.0048 0.0129
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0194 0.0685
Schistosoma mansoni ATP-diphosphohydrolase 1 0.042 0.2508 0.2508
Brugia malayi regulator of G-protein signaling egl-10 0.0038 0.0194 0.0722
Toxoplasma gondii PPIC-type PPIASE domain-containing protein 0.001 0.0023 0.0055
Echinococcus multilocularis g protein coupled receptor 0.0048 0.0254 0.0238
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0023 0.0102 0.0358
Loa Loa (eye worm) PDE1B protein 0.0023 0.0102 0.0347
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0048 0.0254 0.0968
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0048 0.0254 0.0254
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.0001 0.000000000079038
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0038 0.0194 0.0722
Loa Loa (eye worm) RGS-3 protein 0.0038 0.0194 0.0722
Brugia malayi PXA domain containing protein 0.0038 0.0194 0.0722
Loa Loa (eye worm) hypothetical protein 0.0048 0.0254 0.0968
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0023 0.0102 0.0358
Brugia malayi hypothetical protein 0.0048 0.0254 0.0968
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0017 0.0063 0.0047
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0063 0.0327
Mycobacterium ulcerans hypothetical protein 0.002 0.0081 0.0269
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0048 0.0254 0.0254
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0014 0.0048 0.0204
Echinococcus granulosus expressed protein 0.0033 0.016 0.0144
Brugia malayi hypothetical protein 0.0038 0.0194 0.0722
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0048 0.0254 0.0254
Schistosoma mansoni guanosine-diphosphatase 0.004 0.0202 0.0202
Plasmodium falciparum apyrase, putative 0.042 0.2508 1
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0014 0.0048 0.029
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0038 0.0194 0.0722
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0048 0.0254 0.0968
Echinococcus multilocularis g-protein coupled receptor 0.0048 0.0254 0.0238
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0063 0.0327
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.006 0.0326 0.0309
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0023 0.0102 0.0358
Onchocerca volvulus 0.0048 0.0254 0.0745
Loa Loa (eye worm) hypothetical protein 0.0048 0.0254 0.0968
Echinococcus granulosus hypothetical protein 0.0048 0.0254 0.0238
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0023 0.0102 0.0632
Echinococcus granulosus biogenic amine 5HT receptor 0.0048 0.0254 0.0238
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0048 0.0254 0.0238
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.011 0.0627 0.4772
Schistosoma mansoni serine/threonine protein kinase 0.0038 0.0194 0.0194
Schistosoma mansoni opsin-like receptor 0.0048 0.0254 0.0254

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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