Detailed information for compound 1561356

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 627.904 | Formula: C41H47N4S+
  • H donors: 0 H acceptors: 1 LogP: 13.01 Rotable bonds: 16
    Rule of 5 violations (Lipinski): 2
  • SMILES: CCCCCCCCCCCC[n+]1c(/C=C/N(c2ccccc2)C)n(c2c1cc(cc2)c1nc2c(s1)cccc2)c1ccccc1
  • InChi: 1S/C41H47N4S/c1-3-4-5-6-7-8-9-10-11-20-30-44-38-32-33(41-42-36-25-18-19-26-39(36)46-41)27-28-37(38)45(35-23-16-13-17-24-35)40(44)29-31-43(2)34-21-14-12-15-22-34/h12-19,21-29,31-32H,3-11,20,30H2,1-2H3/q+1
  • InChiKey: GSYGZHJTGVXMEC-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.0027 0.0021
Echinococcus multilocularis Furin 1 0.0033 0.0068 0.0046
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0919 0.3576 0.8123
Loa Loa (eye worm) subtilase 0.1082 0.4224 0.4211
Mycobacterium tuberculosis Probable peptidase 0.0564 0.2172 0.6679
Plasmodium vivax hypothetical protein, conserved 0.0291 0.109 0.4227
Echinococcus multilocularis apoptotic protease activating factor 1 0.0064 0.0187 0.0165
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0564 0.2172 0.8508
Trypanosoma cruzi prolyl endopeptidase 0.1126 0.4398 1
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0564 0.2172 1
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0564 0.2172 0.4918
Brugia malayi hypothetical protein 0.0025 0.0034 0.0012
Echinococcus granulosus GA binding protein alpha chain 0.0072 0.022 0.0198
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0033 0.0068 0.0428
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0022 0.0022 0.005
Echinococcus multilocularis dna polymerase kappa 0.004 0.0096 0.0074
Echinococcus multilocularis inhibitor of apoptosis protein 0.0247 0.0912 0.0892
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0096 0.0218
Echinococcus granulosus Dipeptidyl peptidase 9 0.0919 0.3576 0.3562
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0082 0.026 0.0239
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0291 0.109 0.2478
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1126 0.4398 0.4386
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0291 0.109 1
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.0027 0.001
Echinococcus multilocularis prolyl endopeptidase 0.1126 0.4398 0.4386
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP4 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-4) 0.0033 0.0068 0.0155
Toxoplasma gondii subtilisin SUB11 0.0033 0.0068 0.0104
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0033 0.0068 0.0428
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0096 0.0274
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0022 0.0022 0.005
Loa Loa (eye worm) proprotein convertase 2 0.0033 0.0068 0.0046
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0034 0.0028
Entamoeba histolytica hypothetical protein, conserved 0.0291 0.109 1
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0033 0.0068 0.0428
Mycobacterium tuberculosis Probable proline rich membrane-anchored mycosin MycP5 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-5) 0.0033 0.0068 0.0155
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.1126 0.4398 1
Loa Loa (eye worm) hypothetical protein 0.0082 0.026 0.0239
Brugia malayi polk-prov protein 0.0031 0.0057 0.0035
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0033 0.0068 0.0428
Brugia malayi proprotein convertase 2 0.0033 0.0068 0.0046
Brugia malayi Fli-1 protein 0.0218 0.0799 0.0779
Brugia malayi prolyl oligopeptidase family protein 0.0291 0.109 0.107
Plasmodium falciparum subtilisin-like protease 2 0.0033 0.0068 0.0181
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0564 0.2172 0.4938
Mycobacterium ulcerans membrane-anchored serine protease (mycosin), MycP4 0.0033 0.0068 0.0163
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0033 0.0068 0.0428
Brugia malayi celfurPC protein 0.0033 0.0068 0.0046
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0096 0.0218
Leishmania major cathepsin L-like protease 0.0022 0.0022 0.001
Schistosoma mansoni inhibitor of apoptosis protein 0.0247 0.0912 0.0892
Leishmania major oligopeptidase b 0.0564 0.2172 0.4918
Plasmodium falciparum subtilisin-like protease 1 0.0033 0.0068 0.0181
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0068 0.0428
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0291 0.109 1
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0919 0.3576 0.8124
Trypanosoma brucei serine peptidase, clan SB, family S8-like protein 0.0033 0.0068 0.0154
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.254 1 1
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0291 0.109 1
Brugia malayi endoprotease bli-4 precursor 0.0033 0.0068 0.0046
Entamoeba histolytica fatty acid elongase, putative 0.0086 0.0275 0.2365
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.0835 0.3243 1
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0033 0.0068 0.0428
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP3 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-3) 0.0033 0.0068 0.0155
Trypanosoma brucei subtilisin peptidase 0.0033 0.0068 0.0154
Entamoeba histolytica fatty acid elongase, putative 0.0086 0.0275 0.2365
Brugia malayi prolyl oligopeptidase family protein 0.0291 0.109 0.107
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0033 0.0068 0.0428
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0027 0.0018
Loa Loa (eye worm) hypothetical protein 0.0031 0.0057 0.0035
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0291 0.109 0.107
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0027 0.0018
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0034 0.0078
Loa Loa (eye worm) hypothetical protein 0.0033 0.0068 0.0046
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0022 0.0022 0.005
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0033 0.0068 0.0428
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0096 0.0274
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0057 0.0129
Toxoplasma gondii subtilisin SUB1 0.0033 0.0068 0.0104
Leishmania major cysteine peptidase A (CPA) 0.0022 0.0022 0.001
Entamoeba histolytica prolyl oligopeptidase family protein 0.0291 0.109 1
Loa Loa (eye worm) fli-1 protein 0.0218 0.0799 0.0779
Toxoplasma gondii subtilisin SUB10 0.0033 0.0068 0.0104
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0033 0.0068 0.0428
Echinococcus granulosus acylamino acid releasing enzyme 0.0291 0.109 0.107
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0022 0.0022 0.005
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0022 0.0022 0.005
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0033 0.0068 0.0104
Trypanosoma cruzi oligopeptidase b 0.0564 0.2172 0.4913
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0096 0.0218
Onchocerca volvulus 0.0033 0.0068 0.0046
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0033 0.0068 0.0428
Brugia malayi neuroendocrine convertase 1 precursor 0.0033 0.0068 0.0046
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0291 0.109 0.244
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0022 0.0022 0.005
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0068 0.0428
Entamoeba histolytica fatty acid elongase, putative 0.0086 0.0275 0.2365
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0096 0.0218
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0919 0.3576 0.3562
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0096 0.0168
Leishmania major cathepsin L-like protease 0.0022 0.0022 0.001
Plasmodium vivax beta-ketoacyl-acyl carrier protein synthase III precursor, putative 0.0659 0.2548 1
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0247 0.0912 0.0892
Mycobacterium leprae PROBABLE PROLINE RICH MEMBRANE-ANCHORED MYCOSIN MYCP5 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-5) 0.0033 0.0068 0.0191
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0247 0.0912 0.0892
Toxoplasma gondii hypothetical protein 0.0291 0.109 0.244
Onchocerca volvulus 0.0064 0.0187 0.0165
Echinococcus multilocularis caspase 2 0.0064 0.0187 0.0165
Schistosoma mansoni hypothetical protein 0.0247 0.0912 0.0892
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0291 0.109 1
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0033 0.0068 0.0428
Onchocerca volvulus Prolyl endopeptidase homolog 0.1126 0.4398 0.4386
Echinococcus multilocularis acylamino acid releasing enzyme 0.0291 0.109 0.107
Trypanosoma cruzi hypothetical protein, conserved 0.0291 0.109 0.244
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0034 0.0049
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0033 0.0068 0.0428
Echinococcus granulosus membrane bound transcription factor site 1 0.0033 0.0068 0.0046
Loa Loa (eye worm) hypothetical protein 0.0061 0.0179 0.0157
Echinococcus multilocularis 0.0033 0.0068 0.0046
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0023 0.0027 0.5
Giardia lamblia Alanyl dipeptidyl peptidase 0.0291 0.109 1
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.254 1 1
Brugia malayi hypothetical protein 0.0628 0.2422 0.2405
Echinococcus granulosus L aminoadipate semialdehyde 0.0082 0.026 0.0239
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0096 0.0218
Echinococcus granulosus dna polymerase kappa 0.004 0.0096 0.0074
Mycobacterium ulcerans beta-ketoacyl synthase-like protein 0.0659 0.2548 1
Mycobacterium ulcerans proline rich membrane-anchored mycosin MycP5 0.0033 0.0068 0.0163
Loa Loa (eye worm) hypothetical protein 0.0064 0.0187 0.0165
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0034 0.0028
Leishmania major cathepsin L-like protease 0.0022 0.0022 0.001
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0033 0.0068 0.0428
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0033 0.0068 0.0428
Leishmania major cathepsin L-like protease 0.0022 0.0022 0.001
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0018 0.004
Echinococcus multilocularis GA binding protein alpha chain 0.0072 0.022 0.0198
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0057 0.0129
Plasmodium vivax subtilisin-like serine protease, putative 0.0033 0.0068 0.0181
Mycobacterium tuberculosis Probable alanine and proline rich membrane-anchored mycosin MycP2 (serine protease) (subtilisin-like protease) (subtilase-like) 0.0033 0.0068 0.0155
Toxoplasma gondii subtilisin SUB4 0.0033 0.0068 0.0104
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0033 0.0068 0.0428
Leishmania major subtilisin-like serine peptidase 0.0033 0.0068 0.0114
Schistosoma mansoni site-1 peptidase (S08 family) 0.0033 0.0068 0.0046
Loa Loa (eye worm) hypothetical protein 0.0247 0.0912 0.0892
Wolbachia endosymbiont of Brugia malayi 3-oxoacyl-ACP synthase 0.0659 0.2548 1
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0068 0.0428
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0919 0.3576 0.8132
Echinococcus granulosus inhibitor of apoptosis protein 0.0247 0.0912 0.0892
Trypanosoma brucei prolyl endopeptidase 0.1126 0.4398 1
Plasmodium vivax subtilisin-like protease 2, putative 0.0033 0.0068 0.0181
Echinococcus granulosus furin 0.0033 0.0068 0.0046
Trypanosoma cruzi subtilisin peptidase 0.0033 0.0068 0.0104
Mycobacterium leprae Possible secreted protease 0.0033 0.0068 0.0191
Brugia malayi prolyl oligopeptidase family protein 0.0919 0.3576 0.3562
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.254 1 1
Loa Loa (eye worm) hypothetical protein 0.1126 0.4398 0.4386
Schistosoma mansoni hypothetical protein 0.0064 0.0187 0.0165
Echinococcus multilocularis neuroendocrine convertase 2 0.0033 0.0068 0.0046
Schistosoma mansoni caspase-7 (C14 family) 0.0064 0.0187 0.0165
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0022 0.0022 0.005
Leishmania major hypothetical protein, conserved 0.0025 0.0034 0.0038
Leishmania major cathepsin L-like protease 0.0022 0.0022 0.001
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0247 0.0912 0.0892
Echinococcus multilocularis geminin 0.0165 0.0589 0.0568
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0072 0.022 0.0198
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0919 0.3576 0.8123
Onchocerca volvulus 0.0247 0.0912 0.0892
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0033 0.0068 0.0428
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0247 0.0912 0.0892
Trypanosoma brucei DNA polymerase IV, putative 0.0034 0.007 0.0159
Loa Loa (eye worm) prolyl oligopeptidase 0.0291 0.109 0.107
Toxoplasma gondii subtilisin SUB6 0.0033 0.0068 0.0104
Plasmodium vivax subtilisin-like protease 1 0.0033 0.0068 0.0181
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0033 0.0068 0.0428
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0033 0.0068 0.0428
Toxoplasma gondii subtilisin SUB12 0.0033 0.0068 0.0104
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0033 0.0068 0.0428
Loa Loa (eye worm) endoprotease bli-4 0.0033 0.0068 0.0046
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0096 0.0168
Brugia malayi Ets-domain containing protein 0.0072 0.022 0.0198
Loa Loa (eye worm) prolyl oligopeptidase 0.254 1 1
Echinococcus granulosus geminin 0.0165 0.0589 0.0568
Echinococcus granulosus peptidase s8 s53 subtilisin kexin sedolisin 0.0405 0.1541 0.1522
Toxoplasma gondii prolyl endopeptidase 0.1126 0.4398 1
Chlamydia trachomatis oxoacyl-ACP synthase III 0.0659 0.2548 1
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0919 0.3576 0.8123
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0564 0.2172 0.4913
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.004 0.0096 0.069
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0096 0.0168
Loa Loa (eye worm) hypothetical protein 0.0291 0.109 0.107
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0033 0.0068 0.0428
Brugia malayi Hypothetical subtilase-type proteinase F21H12.6 in chromosome II 0.0033 0.0068 0.0046
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.0027 0.001
Trichomonas vaginalis DNA polymerase eta, putative 0.004 0.0096 0.069
Loa Loa (eye worm) hypothetical protein 0.0025 0.0034 0.0012
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0033 0.0068 0.0428
Leishmania major cathepsin L-like protease 0.0022 0.0022 0.001
Mycobacterium ulcerans 3-oxoacyl-ACP synthase 0.0659 0.2548 1
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0034 0.0028
Schistosoma mansoni furin-1 (S08 family) 0.0033 0.0068 0.0046
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0096 0.0218
Toxoplasma gondii subtilisin SUB5 0.0033 0.0068 0.0104
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.254 1 1
Echinococcus granulosus Furin 1 0.0033 0.0068 0.0046
Trypanosoma cruzi hypothetical protein, conserved 0.0291 0.109 0.244
Mycobacterium tuberculosis 3-oxoacyl-[acyl-carrier-protein] synthase III FabH (beta-ketoacyl-ACP synthase III) (KAS III) 0.0659 0.2548 0.7845
Loa Loa (eye worm) hypothetical protein 0.0033 0.0068 0.0046
Brugia malayi Ets-domain containing protein 0.0072 0.022 0.0198
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.0027 0.0028
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0033 0.0068 0.0428
Trypanosoma brucei oligopeptidase b 0.0564 0.2172 0.4938
Onchocerca volvulus Cell death protein 3 homolog 0.0064 0.0187 0.0165
Toxoplasma gondii subtilisin SUB8 0.0033 0.0068 0.0104
Brugia malayi Subtilase family protein 0.1082 0.4224 0.4211
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0564 0.2172 0.6679
Schistosoma mansoni hypothetical protein 0.0165 0.0589 0.0568
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.0033 0.0068 0.0046
Brugia malayi Membrane-bound transcription factor site-1 protease precursor 0.0033 0.0068 0.0046
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0033 0.0068 0.0104
Plasmodium falciparum beta-ketoacyl-ACP synthase III 0.0659 0.2548 1
Echinococcus granulosus neuroendocrine convertase 2 0.0033 0.0068 0.0046
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0033 0.0068 0.0428
Echinococcus multilocularis proprotein convertase subtilisin:kexin type 5 0.0033 0.0068 0.0046
Brugia malayi Cell death protein 3 precursor 0.0064 0.0187 0.0165
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0068 0.0428
Schistosoma mansoni tripeptidyl-peptidase II (S08 family) 0.1082 0.4224 0.4211
Echinococcus granulosus prolyl endopeptidase 0.1126 0.4398 0.4386
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0564 0.2172 0.4913
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0027 0.006
Echinococcus granulosus proprotein convertase subtilisin:kexin type 5 0.0033 0.0068 0.0046
Leishmania major cathepsin L-like protease 0.0022 0.0022 0.001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0022 0.0022 0.005
Mycobacterium ulcerans membrane-anchored mycosin MycP3 0.0033 0.0068 0.0163
Trypanosoma brucei unspecified product 0.0034 0.007 0.0159
Brugia malayi prolyl oligopeptidase family protein 0.1126 0.4398 0.4386
Trypanosoma cruzi serine peptidase, clan SB, family S8-like protein 0.0033 0.0068 0.0104
Giardia lamblia Alanyl dipeptidyl peptidase 0.0291 0.109 1
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0096 0.0218
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0034 0.0049
Loa Loa (eye worm) hypothetical protein 0.0064 0.0187 0.0165
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0096 0.0218
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0033 0.0068 0.0428
Entamoeba histolytica fatty acid elongase, putative 0.0086 0.0275 0.2365
Loa Loa (eye worm) hypothetical protein 0.0628 0.2422 0.2405
Echinococcus granulosus caspase 2 0.0064 0.0187 0.0165
Toxoplasma gondii subtilisin SUB2 0.0033 0.0068 0.0104
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0291 0.109 0.107
Echinococcus multilocularis Peptidase S8 S53, subtilisin kexin sedolisin 0.0405 0.1541 0.1522
Schistosoma mansoni ets-related 0.0218 0.0799 0.0779
Schistosoma mansoni site-1 peptidase (S08 family) 0.0033 0.0068 0.0046
Entamoeba histolytica prolyl oligopeptidase family protein 0.0291 0.109 1
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.0033 0.0068 0.0046
Trichomonas vaginalis conserved hypothetical protein 0.0291 0.109 1
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0033 0.0068 0.0428
Schistosoma mansoni hypothetical protein 0.0165 0.0589 0.0568
Echinococcus multilocularis L aminoadipate semialdehyde 0.0082 0.026 0.0239
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0919 0.3576 0.3562
Plasmodium falciparum peptidase, putative 0.0291 0.109 0.4227
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0033 0.0068 0.0428
Trypanosoma cruzi oligopeptidase b 0.0564 0.2172 0.4913
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0096 0.0218
Brugia malayi hypothetical protein 0.0064 0.0187 0.0165
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0033 0.0068 0.0428
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0082 0.026 0.0239
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0034 0.0049
Mycobacterium ulcerans 3-oxoacyl-ACP synthase 0.0659 0.2548 1
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0919 0.3576 0.8132
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1126 0.4398 0.4386
Schistosoma mansoni subfamily S8B non-peptidase homologue (S08 family) 0.0033 0.0068 0.0046
Entamoeba histolytica hypothetical protein 0.0023 0.0027 0.0043
Onchocerca volvulus Deterin homolog 0.0247 0.0912 0.0892
Echinococcus multilocularis membrane bound transcription factor site 1 0.0033 0.0068 0.0046
Leishmania major cathepsin L-like protease 0.0022 0.0022 0.001
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0247 0.0912 0.0892
Schistosoma mansoni gabp alpha 0.0072 0.022 0.0198
Loa Loa (eye worm) hypothetical protein 0.0247 0.0912 0.0892
Onchocerca volvulus 0.0082 0.026 0.0239
Trypanosoma brucei prolyl oligopeptidase, putative 0.0564 0.2172 0.4938
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0033 0.0068 0.0428
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0068 0.0428
Mycobacterium leprae PROBABLE MEMBRANE-ANCHORED MYCOSIN MYCP3 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-3) 0.0033 0.0068 0.0191
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0033 0.0068 0.0428
Entamoeba histolytica fatty acid elongase, putative 0.0086 0.0275 0.2365
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0033 0.0068 0.0428
Toxoplasma gondii subtilisin SUB7 0.0033 0.0068 0.0104
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0033 0.0068 0.0428
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0022 0.0022 0.005
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0022 0.0022 0.005
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0096 0.0218
Entamoeba histolytica prolyl oligopeptidase family protein 0.0291 0.109 1
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0096 0.0218
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0022 0.0022 0.005
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0096 0.0168
Echinococcus granulosus apoptotic protease activating factor 1 0.0064 0.0187 0.0165
Loa Loa (eye worm) hypothetical protein 0.0291 0.109 0.107
Toxoplasma gondii subtilisin SUB9 0.0033 0.0068 0.0104
Plasmodium falciparum subtilisin-like protease 3 0.0033 0.0068 0.0181
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0033 0.0068 0.0428

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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