Detailed information for compound 160001

Basic information

Technical information
  • TDR Targets ID: 160001
  • Name: (2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[( 2-benzyl-3-phenylpropanoyl)amino]-3-methylbut anoyl]amino]-3-methylbutanoyl]amino]-4-oxo-4- pyrrolidin-1-ylbutanoyl]amino]-4-hydroxy-4-ox obutanoyl]amino]-4-methylpentanoic acid
  • MW: 834.997 | Formula: C44H62N6O10
  • H donors: 7 H acceptors: 10 LogP: 4.34 Rotable bonds: 29
    Rule of 5 violations (Lipinski): 3
  • SMILES: CC(C[C@@H](C(=O)O)NC(=O)[C@@H](NC(=O)[C@H](CC(=O)N1CCCC1)NC(=O)[C@H](C(C)C)NC(=O)[C@H](C(C)C)NC(=O)C(Cc1ccccc1)Cc1ccccc1)CC(=O)O)C
  • InChi: 1S/C44H62N6O10/c1-26(2)21-34(44(59)60)47-41(56)33(25-36(52)53)45-40(55)32(24-35(51)50-19-13-14-20-50)46-42(57)37(27(3)4)49-43(58)38(28(5)6)48-39(54)31(22-29-15-9-7-10-16-29)23-30-17-11-8-12-18-30/h7-12,15-18,26-28,31-34,37-38H,13-14,19-25H2,1-6H3,(H,45,55)(H,46,57)(H,47,56)(H,48,54)(H,49,58)(H,52,53)(H,59,60)/t32-,33-,34-,37-,38-/m0/s1
  • InChiKey: AGVDOEDTEWLKPJ-GMQPWBGISA-N  


Substructure search Similarity search

Network

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Synonyms

  • (2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[(2-benzyl-3-phenyl-propanoyl)amino]-3-methyl-butanoyl]amino]-3-methyl-butanoyl]amino]-4-oxo-4-pyrrolidin-1-yl-butanoyl]amino]-4-hydroxy-4-oxo-butanoyl]amino]-4-methyl-pentanoic acid
  • (2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[(2-benzyl-1-oxo-3-phenylpropyl)amino]-3-methyl-1-oxobutyl]amino]-3-methyl-1-oxobutyl]amino]-1,4-dioxo-4-(1-pyrrolidinyl)butyl]amino]-4-hydroxy-1,4-dioxobutyl]amino]-4-methylpentanoic acid
  • (2S)-2-[[(2S)-4-hydroxy-2-[[(2S)-2-[[(2S)-3-methyl-2-[[(2S)-3-methyl-2-[[3-phenyl-2-(phenylmethyl)propanoyl]amino]butanoyl]amino]butanoyl]amino]-4-oxo-4-pyrrolidin-1-yl-butanoyl]amino]-4-oxo-butanoyl]amino]-4-methyl-pentanoic acid
  • (2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[(2-benzyl-3-phenyl-propanoyl)amino]-3-methyl-butanoyl]amino]-3-methyl-butanoyl]amino]-4-keto-4-pyrrolidino-butanoyl]amino]-4-hydroxy-4-keto-butanoyl]amino]-4-methyl-valeric acid
  • (2S)-2-[[(2S)-4-hydroxy-2-[[(2S)-2-[[(2S)-3-methyl-2-[[(2S)-3-methyl-2-[[3-phenyl-2-(phenylmethyl)propanoyl]amino]butanoyl]amino]butanoyl]amino]-4-oxo-4-pyrrolidin-1-ylbutanoyl]amino]-4-oxobutanoyl]amino]-4-methylpentanoic acid
  • (2S)-2-[[(2S)-4-hydroxy-2-[[(2S)-2-[[(2S)-3-methyl-2-[[(2S)-3-methyl-1-oxo-2-[[1-oxo-3-phenyl-2-(phenylmethyl)propyl]amino]butyl]amino]-1-oxobutyl]amino]-1,4-dioxo-4-1-pyrrolidinylbutyl]amino]-1,4-dioxobutyl]amino]-4-methylpentanoic acid
  • (2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-(benzyl)-3-phenyl-propanoyl]amino]-3-methyl-butanoyl]amino]-3-methyl-butanoyl]amino]-4-keto-4-pyrrolidin-1-yl-butanoyl]amino]-4-hydroxy-4-keto-butanoyl]amino]-4-methyl-valeric acid
  • 2-[2-(2-{2-[2-(2-Benzyl-3-phenyl-propionylamino)-3-methyl-butyrylamino]-3-methyl-butyrylamino}-4-oxo-4-pyrrolidin-1-yl-butyrylamino)-3-carboxy-propionylamino]-4-methyl-pentanoic acid
  • AIDS-188203
  • AIDS188203

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens ribonucleotide reductase M1 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Leishmania donovani ribonucleoside-diphosphate reductase large chain, putative Get druggable targets OG5_126839 All targets in OG5_126839
Leishmania major ribonucleoside-diphosphate reductase large chain, putative Get druggable targets OG5_126839 All targets in OG5_126839
Cryptosporidium parvum ribonucleotide-diphosphate reductase large chain; RIR1; c-terminal PFL-like glycyl radical enzymes-like fold Get druggable targets OG5_126839 All targets in OG5_126839
Schistosoma mansoni ribonucleoside-diphosphate reductase alpha subunit Get druggable targets OG5_126839 All targets in OG5_126839
Leishmania mexicana ribonucleoside-diphosphate reductase large chain, putative Get druggable targets OG5_126839 All targets in OG5_126839
Candida albicans one of two likely ribonucleotide reductase large subunit genes similar to S. cerevisiae RNR1 (YER070W) and RNR3 (YIL066C) Get druggable targets OG5_126839 All targets in OG5_126839
Candida albicans one of two likely ribonucleotide reductase large subunit genes similar to S. cerevisiae RNR1 (YER070W) and RNR3 (YIL066C) Get druggable targets OG5_126839 All targets in OG5_126839
Cryptosporidium hominis ribonucleoside-diphosphate reductase large chain (ribonucleotide reductase R1 subunit) Get druggable targets OG5_126839 All targets in OG5_126839
Brugia malayi ribonucleoside-diphosphate reductase large chain, putative Get druggable targets OG5_126839 All targets in OG5_126839
Toxoplasma gondii ribonucleoside-diphosphate reductase large chain Get druggable targets OG5_126839 All targets in OG5_126839
Trypanosoma cruzi ribonucleoside-diphosphate reductase large chain, putative Get druggable targets OG5_126839 All targets in OG5_126839
Babesia bovis ribonucleoside-diphosphate reductase large chain Get druggable targets OG5_126839 All targets in OG5_126839
Neospora caninum ribonucleoside-diphosphate reductase, large subunit, putative Get druggable targets OG5_126839 All targets in OG5_126839
Mycobacterium ulcerans ribonucleotide-diphosphate reductase subunit alpha Get druggable targets OG5_126839 All targets in OG5_126839
Plasmodium yoelii ribonucleoside-diphosphate reductase large chain Get druggable targets OG5_126839 All targets in OG5_126839
Candida albicans one of two likely ribonucleotide reductase large subunit genes similar to S. cerevisiae RNR1 (YER070W) and RNR3 (YIL066C) Get druggable targets OG5_126839 All targets in OG5_126839
Wolbachia endosymbiont of Brugia malayi ribonucleotide-diphosphate reductase subunit alpha Get druggable targets OG5_126839 All targets in OG5_126839
Plasmodium falciparum ribonucleoside-diphosphate reductase large subunit, putative Get druggable targets OG5_126839 All targets in OG5_126839
Trypanosoma brucei gambiense ribonucleoside-diphosphate reductase large chain Get druggable targets OG5_126839 All targets in OG5_126839
Trypanosoma congolense ribonucleoside-diphosphate reductase large chain Get druggable targets OG5_126839 All targets in OG5_126839
Candida albicans one of two likely ribonucleotide reductase large subunit genes similar to S. cerevisiae RNR1 (YER070W) and RNR3 (YIL066C) Get druggable targets OG5_126839 All targets in OG5_126839
Mycobacterium tuberculosis Probable ribonucleoside-diphosphate reductase (large subunit) NrdZ (ribonucleotide reductase) Get druggable targets OG5_126839 All targets in OG5_126839
Trypanosoma congolense ribonucleoside-diphosphate reductase large chain Get druggable targets OG5_126839 All targets in OG5_126839
Echinococcus multilocularis ribonucleoside diphosphate reductase large Get druggable targets OG5_126839 All targets in OG5_126839
Plasmodium berghei ribonucleoside-diphosphate reductase large subunit, putative Get druggable targets OG5_126839 All targets in OG5_126839
Echinococcus granulosus ribonucleoside diphosphate reductase large Get druggable targets OG5_126839 All targets in OG5_126839
Schistosoma japonicum ko:K00525 ribonucleoside-diphosphate reductase alpha chain [EC1.17.4.1A], putative Get druggable targets OG5_126839 All targets in OG5_126839
Mycobacterium leprae RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE (ALPHA CHAIN) NRDE (RIBONUCLEOTIDE REDUCTASE SMALL SUBUNIT) (R1F PROTEIN) Get druggable targets OG5_126839 All targets in OG5_126839
Mycobacterium tuberculosis Ribonucleoside-diphosphate reductase (alpha chain) NrdE (ribonucleotide reductase small subunit) (R1F protein) Get druggable targets OG5_126839 All targets in OG5_126839
Theileria parva ribonucleotide-diphosphate reductase large subunit, putative Get druggable targets OG5_126839 All targets in OG5_126839
Leishmania braziliensis ribonucleoside-diphosphate reductase large chain, putative Get druggable targets OG5_126839 All targets in OG5_126839
Trichomonas vaginalis ribonucleoside-diphosphate reductase alpha chain, putative Get druggable targets OG5_126839 All targets in OG5_126839
Trypanosoma brucei ribonucleoside-diphosphate reductase large chain Get druggable targets OG5_126839 All targets in OG5_126839
Plasmodium knowlesi ribonucleoside-diphosphate reductase large subunit, putative Get druggable targets OG5_126839 All targets in OG5_126839
Chlamydia trachomatis ribonucleoside-diphosphate reductase subunit alpha Get druggable targets OG5_126839 All targets in OG5_126839
Loa Loa (eye worm) ribonucleoside-diphosphate reductase large subunit Get druggable targets OG5_126839 All targets in OG5_126839
Treponema pallidum ribonucleotide-diphosphate reductase subunit alpha Get druggable targets OG5_126839 All targets in OG5_126839
Leishmania infantum ribonucleoside-diphosphate reductase large chain, putative Get druggable targets OG5_126839 All targets in OG5_126839
Plasmodium vivax ribonucleoside-diphosphate reductase large chain, putative Get druggable targets OG5_126839 All targets in OG5_126839
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0043 0.2314 0.2847
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0043 0.2314 0.2847
Leishmania major ribonucleoside-diphosphate reductase large chain, putative 0.0121 1 1
Toxoplasma gondii ribonucleoside-diphosphate reductase large chain 0.0121 1 1
Echinococcus granulosus ribonucleoside diphosphate reductase large 0.0121 1 1
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0043 0.2314 0.2847
Schistosoma mansoni nardilysin (M16 family) 0.0047 0.2703 0.2703
Schistosoma mansoni insulysin (M16 family) 0.0026 0.064 0.064
Mycobacterium tuberculosis Ribonucleoside-diphosphate reductase (alpha chain) NrdE (ribonucleotide reductase small subunit) (R1F protein) 0.0102 0.8127 1
Mycobacterium leprae RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE (ALPHA CHAIN) NRDE (RIBONUCLEOTIDE REDUCTASE SMALL SUBUNIT) (R1F PROTEIN) 0.0102 0.8127 1
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0043 0.2314 0.2847
Treponema pallidum ribonucleotide-diphosphate reductase subunit alpha 0.0121 1 1
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0043 0.2314 0.2847
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0043 0.2314 0.2847
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0043 0.2314 0.2847
Schistosoma mansoni cytochrome P450 0.0043 0.2314 0.2314
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0043 0.2314 0.2314
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0043 0.2314 0.2847
Toxoplasma gondii insulysin, putative 0.0045 0.2475 0.2475
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0043 0.2314 0.2314
Schistosoma mansoni ribonucleoside-diphosphate reductase alpha subunit 0.0121 1 1
Echinococcus multilocularis nardilysin 0.0029 0.0869 0.0869
Loa Loa (eye worm) CYP4Cod1 0.0043 0.2314 0.2314
Leishmania major cytochrome p450-like protein 0.0043 0.2314 0.2314
Trypanosoma cruzi cytochrome P450, putative 0.0043 0.2314 0.2314
Trypanosoma cruzi peptidase, putative 0.0047 0.2703 0.2703
Toxoplasma gondii sporozoite developmental protein 0.0047 0.2703 0.2703
Plasmodium vivax ribonucleoside-diphosphate reductase large chain, putative 0.0121 1 1
Brugia malayi Cytochrome P450 family protein 0.0043 0.2314 0.2314
Schistosoma mansoni insulysin unit 3 (M16 family) 0.0047 0.2703 0.2703
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0043 0.2314 0.2847
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0043 0.2314 0.2847
Leishmania major cytochrome p450-like protein 0.0043 0.2314 0.2314
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0043 0.2314 0.2847
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0043 0.2314 0.2847
Brugia malayi insulin-degrading enzyme 0.0047 0.2703 0.2703
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0043 0.2314 0.2847
Trypanosoma brucei cytochrome P450, putative 0.0043 0.2314 0.2314
Loa Loa (eye worm) cytochrome P450 family protein 0.0043 0.2314 0.2314
Mycobacterium tuberculosis Probable ribonucleoside-diphosphate reductase (large subunit) NrdZ (ribonucleotide reductase) 0.0037 0.1678 0.2065
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0043 0.2314 0.2314
Schistosoma mansoni insulysin unit 3 (M16 family) 0.0047 0.2703 0.2703
Echinococcus granulosus nardilysin 0.0047 0.2703 0.2703
Chlamydia trachomatis ribonucleoside-diphosphate reductase subunit alpha 0.0121 1 1
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0043 0.2314 0.2847
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0043 0.2314 0.2847
Trypanosoma cruzi ribonucleoside-diphosphate reductase large chain, putative 0.0121 1 1
Loa Loa (eye worm) insulin-degrading enzyme 0.0047 0.2703 0.2703
Schistosoma mansoni hypothetical protein 0.0043 0.2314 0.2314
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0043 0.2314 0.2314
Mycobacterium ulcerans ribonucleotide-diphosphate reductase subunit alpha 0.0102 0.8127 1
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0043 0.2314 0.2847
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0043 0.2314 0.2847
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0043 0.2314 0.2847
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0043 0.2314 0.2847
Toxoplasma gondii peptidase M16 inactive domain-containing protein 0.0029 0.0869 0.0869
Brugia malayi Cytochrome P450 family protein 0.0043 0.2314 0.2314
Trypanosoma brucei peptidase, putative 0.0047 0.2703 0.2703
Trypanosoma brucei ribonucleoside-diphosphate reductase large chain 0.0121 1 1
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0043 0.2314 0.2847
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0 0.5
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0043 0.2314 0.2847
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0043 0.2314 0.2847
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0043 0.2314 0.2847
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0043 0.2314 0.2847
Echinococcus multilocularis 0.0043 0.2314 0.2314
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0043 0.2314 0.2847
Trichomonas vaginalis ribonucleoside-diphosphate reductase alpha chain, putative 0.0102 0.8127 1
Echinococcus granulosus insulin degrading enzyme 0.0047 0.2703 0.2703
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0043 0.2314 0.2847
Trypanosoma cruzi ribonucleoside-diphosphate reductase large chain, putative 0.0031 0.1147 0.1147
Echinococcus multilocularis ribonucleoside diphosphate reductase large 0.0121 1 1
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0043 0.2314 0.2847
Toxoplasma gondii rhoptry metalloprotease toxolysin TLN1 0.0047 0.2703 0.2703
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0043 0.2314 0.2847
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0043 0.2314 0.2847
Echinococcus granulosus 3'partial|nardilysin 0.0047 0.2703 0.2703
Toxoplasma gondii cytochrome p450 superfamily protein 0.0043 0.2314 0.2314
Schistosoma mansoni nardilysin (M16 family) 0.0047 0.2703 0.2703
Echinococcus multilocularis nardilysin 0.0047 0.2703 0.2703
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0043 0.2314 0.2847
Brugia malayi cytochrome P450 0.0043 0.2314 0.2314
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0043 0.2314 0.2847
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0043 0.2314 0.2847
Loa Loa (eye worm) cytochrome P450 family protein 0.0043 0.2314 0.2314
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0043 0.2314 0.2847
Plasmodium falciparum ribonucleoside-diphosphate reductase large subunit, putative 0.0121 1 1
Echinococcus granulosus 5'partial|nardilysin 0.0021 0.012 0.012
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0043 0.2314 0.2847
Brugia malayi Cytochrome P450 family protein 0.0043 0.2314 0.2314
Echinococcus multilocularis nardilysin 0.0047 0.2703 0.2703
Toxoplasma gondii toxolysin TLN4 0.0021 0.012 0.012
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0043 0.2314 0.2847
Leishmania major cytochrome p450-like protein 0.0043 0.2314 0.2314
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0043 0.2314 0.2847
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0043 0.2314 0.2847
Loa Loa (eye worm) cytochrome P450 family protein 0.0043 0.2314 0.2314
Echinococcus granulosus cytochrome P450 2K1 0.0043 0.2314 0.2314
Echinococcus multilocularis insulin degrading enzyme 0.0047 0.2703 0.2703
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0043 0.2314 0.2847
Wolbachia endosymbiont of Brugia malayi ribonucleotide-diphosphate reductase subunit alpha 0.0102 0.8127 1
Trypanosoma cruzi peptidase, putative 0.0047 0.2703 0.2703
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0043 0.2314 0.2847
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0043 0.2314 0.2314
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.002 0 0.5
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0043 0.2314 0.2847
Leishmania major phosphoglycan beta 1,3 galactosyltransferase 5 0.0047 0.2703 0.2703
Loa Loa (eye worm) cytochrome P450 0.0043 0.2314 0.2314
Loa Loa (eye worm) ribonucleoside-diphosphate reductase large subunit 0.0121 1 1
Trypanosoma cruzi cytochrome P450, putative 0.0043 0.2314 0.2314
Brugia malayi Cytochrome P450 family protein 0.0043 0.2314 0.2314
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0043 0.2314 0.2847

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 0.7 nM Inhibitory potency against Herpes Simplex virus ribonucleotide reductase ChEMBL. No reference
IC50 (binding) = 0.7 nM In vitro inhibitory activity against HSV ribonucleotide reductase ChEMBL. 7658449
IC50 (binding) = 0.7 nM In vitro inhibitory activity against HSV ribonucleotide reductase ChEMBL. 7658449
IC50 (binding) = 22 nM Inhibitory potency against Varicella zoster virus ribonucleotide reductase ChEMBL. No reference
IC50 (binding) = 22 nM Inhibitory potency against Varicella zoster virus ribonucleotide reductase ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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