Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule | 0.0052 | 0.0018 | 0.0016 |
Echinococcus granulosus | neuroglian | 0.0055 | 0.0024 | 0.0031 |
Brugia malayi | Serine carboxypeptidase F41C3.5 precursor | 0.054 | 0.0839 | 0.2823 |
Trichomonas vaginalis | CAMK family protein kinase | 0.1808 | 0.2973 | 1 |
Trypanosoma cruzi | serine carboxypeptidase (CBP1), putative | 0.054 | 0.0839 | 0.2818 |
Echinococcus multilocularis | Immunoglobulin | 0.0239 | 0.0333 | 0.0474 |
Echinococcus granulosus | hemicentin 1 | 0.0052 | 0.0018 | 0.0023 |
Mycobacterium tuberculosis | Possible cytochrome P450 135A1 Cyp135A1 | 0.0268 | 0.0381 | 0.5 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.1808 | 0.2973 | 0.4253 |
Echinococcus multilocularis | Immunoglobulin | 0.0239 | 0.0333 | 0.0474 |
Onchocerca volvulus | 0.011 | 0.0116 | 0.0362 | |
Schistosoma mansoni | serine/threonine protein kinase | 0.0661 | 0.1043 | 0.1042 |
Echinococcus multilocularis | peroxidasin | 0.0052 | 0.0018 | 0.0023 |
Echinococcus multilocularis | roundabout 2 | 0.0055 | 0.0024 | 0.0031 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.019 | 0.025 | 0.0356 |
Entamoeba histolytica | serine/threonine protein kinase 6, putative | 0.0661 | 0.1043 | 0.3506 |
Echinococcus multilocularis | neurotracting:lsamp:neurotrimin:obcam | 0.0052 | 0.0018 | 0.0023 |
Brugia malayi | Cytochrome P450 family protein | 0.0439 | 0.067 | 0.2255 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0661 | 0.1043 | 0.3506 |
Loa Loa (eye worm) | hypothetical protein | 0.0312 | 0.0456 | 0.1534 |
Loa Loa (eye worm) | AUR protein kinase | 0.0661 | 0.1043 | 0.351 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0538 | 0.0837 | 0.1196 |
Mycobacterium tuberculosis | Probable cytochrome P450 132 Cyp132 | 0.0268 | 0.0381 | 0.5 |
Mycobacterium tuberculosis | Possible cytochrome P450 135B1 Cyp135B1 | 0.0268 | 0.0381 | 0.5 |
Mycobacterium tuberculosis | Cytochrome P450 121 Cyp121 | 0.0268 | 0.0381 | 0.5 |
Brugia malayi | serine/threonine protein kinase 6 | 0.0661 | 0.1043 | 0.351 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0042 | 0.0003 | 0.0001 |
Schistosoma mansoni | septate junction protein | 0.0052 | 0.0018 | 0.0016 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0538 | 0.0837 | 0.1196 |
Loa Loa (eye worm) | CAMK protein kinase | 0.0046 | 0.0008 | 0.0029 |
Mycobacterium tuberculosis | Probable cytochrome P450 141 Cyp141 | 0.0268 | 0.0381 | 0.5 |
Trichomonas vaginalis | CAMK family protein kinase | 0.1808 | 0.2973 | 1 |
Schistosoma mansoni | family S10 non-peptidase homologue (S10 family) | 0.054 | 0.0839 | 0.0837 |
Echinococcus multilocularis | family S10 non peptidase ue (S10 family) | 0.0486 | 0.0749 | 0.107 |
Schistosoma mansoni | cell adhesion molecule | 0.0055 | 0.0024 | 0.0022 |
Echinococcus granulosus | lysosomal protective protein | 0.054 | 0.0839 | 0.1199 |
Schistosoma mansoni | lysosomal protective protein precursor (cathepsin A) (carboxypeptidase | 0.0053 | 0.0021 | 0.0019 |
Entamoeba histolytica | protein kinase, putative | 0.0661 | 0.1043 | 0.3506 |
Mycobacterium tuberculosis | Probable cytochrome P450 124 Cyp124 | 0.0268 | 0.0381 | 0.5 |
Trypanosoma cruzi | aurora B kinase, putative | 0.0661 | 0.1043 | 0.3506 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.1808 | 0.2973 | 1 |
Echinococcus multilocularis | lachesin | 0.0052 | 0.0018 | 0.0023 |
Echinococcus granulosus | peroxidasin | 0.0052 | 0.0018 | 0.0023 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0052 | 0.0018 | 0.006 |
Echinococcus granulosus | tyrosine protein kinase otk | 0.0052 | 0.0018 | 0.0023 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase F | 0.0055 | 0.0024 | 0.0031 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0042 | 0.0002 | 0.0007 |
Echinococcus granulosus | roundabout 2 | 0.0294 | 0.0426 | 0.0607 |
Loa Loa (eye worm) | hypothetical protein | 0.054 | 0.0839 | 0.2823 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.1808 | 0.2973 | 1 |
Echinococcus multilocularis | fibroblast growth factor receptor 4 | 0.0121 | 0.0135 | 0.019 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0439 | 0.067 | 0.2255 |
Mycobacterium tuberculosis | Probable cytochrome P450 125 Cyp125 | 0.0268 | 0.0381 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0239 | 0.0334 | 0.1123 |
Echinococcus multilocularis | basic fibroblast growth factor receptor 1 A | 0.0121 | 0.0135 | 0.019 |
Brugia malayi | serine/threonine kinase 12 | 0.0661 | 0.1043 | 0.351 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0018 | 0.006 |
Onchocerca volvulus | Uncharacterized serine carboxypeptidase homolog | 0.054 | 0.0839 | 0.2803 |
Schistosoma mansoni | tyrosine kinase | 0.0121 | 0.0135 | 0.0133 |
Echinococcus granulosus | neuropeptide s receptor | 0.0538 | 0.0837 | 0.1196 |
Echinococcus granulosus | twitchin | 0.0281 | 0.0405 | 0.0577 |
Mycobacterium tuberculosis | Probable cytochrome P450 136 Cyp136 | 0.0268 | 0.0381 | 0.5 |
Schistosoma mansoni | alpha-glucosidase | 0.0163 | 0.0206 | 0.0204 |
Echinococcus granulosus | contactin | 0.0055 | 0.0024 | 0.0031 |
Schistosoma mansoni | tyrosine kinase | 0.0075 | 0.0058 | 0.0056 |
Giardia lamblia | Kinase, PLK | 0.1808 | 0.2973 | 1 |
Loa Loa (eye worm) | AUR protein kinase | 0.0661 | 0.1043 | 0.351 |
Trichomonas vaginalis | AGC family protein kinase | 0.0661 | 0.1043 | 0.3506 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0018 | 0.006 |
Trypanosoma brucei | Lanosterol 14-alpha demethylase | 0.0268 | 0.0381 | 0.1277 |
Loa Loa (eye worm) | hypothetical protein | 0.0265 | 0.0377 | 0.1268 |
Schistosoma mansoni | cytochrome P450 | 0.0268 | 0.0381 | 0.038 |
Loa Loa (eye worm) | CAMK/MLCK protein kinase | 0.0072 | 0.0052 | 0.0175 |
Trichomonas vaginalis | AGC family protein kinase | 0.0661 | 0.1043 | 0.3506 |
Mycobacterium tuberculosis | Possible cytochrome P450 126 Cyp126 | 0.0268 | 0.0381 | 0.5 |
Echinococcus granulosus | titin | 0.0046 | 0.0008 | 0.0009 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0147 | 0.0178 | 0.0598 |
Schistosoma mansoni | cell adhesion molecule | 0.0055 | 0.0024 | 0.0022 |
Mycobacterium leprae | putative cytochrome p450 | 0.0268 | 0.0381 | 0.5 |
Echinococcus multilocularis | basement membrane specific heparan sulfate | 0.0239 | 0.0333 | 0.0474 |
Entamoeba histolytica | serine/threonine- protein kinase 6, putative | 0.0661 | 0.1043 | 0.3506 |
Schistosoma mansoni | serine/threonine protein kinase | 0.1808 | 0.2973 | 0.2971 |
Echinococcus granulosus | fibroblast growth factor receptor 4 | 0.0121 | 0.0135 | 0.019 |
Trypanosoma brucei | aurora B kinase | 0.0661 | 0.1043 | 0.3506 |
Loa Loa (eye worm) | hypothetical protein | 0.0239 | 0.0333 | 0.1121 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.1808 | 0.2973 | 0.4253 |
Trichomonas vaginalis | CAMK family protein kinase | 0.1808 | 0.2973 | 1 |
Echinococcus granulosus | titin | 0.0046 | 0.0008 | 0.0009 |
Loa Loa (eye worm) | AUR protein kinase | 0.0661 | 0.1043 | 0.351 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0052 | 0.0018 | 0.006 |
Schistosoma mansoni | vesicular amine transporter | 0.0239 | 0.0333 | 0.0331 |
Echinococcus granulosus | roundabout 2 | 0.0055 | 0.0024 | 0.0031 |
Loa Loa (eye worm) | hypothetical protein | 0.0239 | 0.0333 | 0.1121 |
Schistosoma mansoni | roundabout | 0.0052 | 0.0018 | 0.0016 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0439 | 0.067 | 0.225 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0268 | 0.0381 | 0.1277 |
Echinococcus granulosus | defective proboscis extension response | 0.0239 | 0.0333 | 0.0474 |
Echinococcus granulosus | neurotracting:lsamp:neurotrimin:obcam | 0.0265 | 0.0377 | 0.0537 |
Echinococcus multilocularis | contactin neuroglian septate junction protein | 0.0055 | 0.0024 | 0.0031 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.1015 | 0.164 | 0.5517 |
Echinococcus granulosus | roundabout 2 | 0.0055 | 0.0024 | 0.0031 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.1808 | 0.2973 | 1 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0052 | 0.0018 | 0.006 |
Trypanosoma cruzi | serine carboxypeptidase (CBP1), putative | 0.054 | 0.0839 | 0.2818 |
Trypanosoma cruzi | serine peptidase, Clan SC, Family S10, putative | 0.054 | 0.0839 | 0.2818 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0439 | 0.067 | 0.2255 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0024 | 0.008 |
Leishmania major | cytochrome p450-like protein | 0.0439 | 0.067 | 0.225 |
Echinococcus multilocularis | 0.0268 | 0.0381 | 0.0543 | |
Schistosoma mansoni | defective proboscis extension response (dpr)-related | 0.0239 | 0.0333 | 0.0331 |
Schistosoma mansoni | titin | 0.0052 | 0.0018 | 0.0016 |
Schistosoma mansoni | protein kinase | 0.0661 | 0.1043 | 0.1042 |
Brugia malayi | Fibronectin type III domain containing protein | 0.0243 | 0.0339 | 0.1141 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0046 | 0.0008 | 0.0029 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0018 | 0.006 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0243 | 0.0339 | 0.1141 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0439 | 0.067 | 1 |
Brugia malayi | serine/threonine-protein kinase 6 | 0.0661 | 0.1043 | 0.351 |
Brugia malayi | Peroxidasin | 0.0052 | 0.0018 | 0.0061 |
Trichomonas vaginalis | AGC family protein kinase | 0.0661 | 0.1043 | 0.3506 |
Loa Loa (eye worm) | hypothetical protein | 0.0291 | 0.042 | 0.1413 |
Schistosoma mansoni | Neurotrimin precursor (hNT) | 0.0239 | 0.0333 | 0.0331 |
Echinococcus granulosus | tyrosine protein kinase transmembrane receptor | 0.0049 | 0.0014 | 0.0018 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0055 | 0.0024 | 0.008 |
Echinococcus granulosus | Serine:threonine protein kinase PLK4 | 0.4193 | 0.6987 | 1 |
Brugia malayi | protein unc-22 | 0.0046 | 0.0008 | 0.0029 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0052 | 0.0018 | 0.006 |
Echinococcus granulosus | aurora kinase A | 0.0661 | 0.1043 | 0.1491 |
Echinococcus granulosus | cytochrome P450 2K1 | 0.0268 | 0.0381 | 0.0543 |
Onchocerca volvulus | 0.1181 | 0.1918 | 0.6441 | |
Brugia malayi | Cytochrome P450 family protein | 0.1015 | 0.164 | 0.5517 |
Plasmodium falciparum | serine/threonine protein kinase, putative | 0.0661 | 0.1043 | 0.5 |
Leishmania major | cytochrome p450-like protein | 0.0268 | 0.0381 | 0.1277 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.1808 | 0.2973 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0018 | 0.0061 |
Brugia malayi | hypothetical protein | 0.0243 | 0.0339 | 0.1141 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0439 | 0.067 | 0.2255 |
Toxoplasma gondii | aurora kinase | 0.0661 | 0.1043 | 1 |
Echinococcus multilocularis | hemicentin 1 | 0.0052 | 0.0018 | 0.0023 |
Echinococcus granulosus | family S10 non peptidase ue S10 family | 0.0486 | 0.0749 | 0.107 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.1808 | 0.2973 | 1 |
Trypanosoma brucei | cytochrome P450, putative | 0.0439 | 0.067 | 0.225 |
Loa Loa (eye worm) | hypothetical protein | 0.0291 | 0.042 | 0.1413 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0052 | 0.0018 | 0.006 |
Schistosoma mansoni | cell adhesion molecule | 0.0052 | 0.0018 | 0.0016 |
Leishmania major | protein kinase, putative | 0.0661 | 0.1043 | 0.3506 |
Entamoeba histolytica | protein kinase, putative | 0.0661 | 0.1043 | 0.3506 |
Echinococcus multilocularis | roundabout 2 | 0.0055 | 0.0024 | 0.0031 |
Echinococcus multilocularis | hemicentin 1 | 0.0052 | 0.0018 | 0.0023 |
Loa Loa (eye worm) | CAMK/MLCK protein kinase | 0.0046 | 0.0008 | 0.0029 |
Echinococcus multilocularis | tyrosine protein kinase transmembrane receptor | 0.0049 | 0.0014 | 0.0018 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0052 | 0.0018 | 0.006 |
Loa Loa (eye worm) | hypothetical protein | 0.0243 | 0.0339 | 0.1141 |
Echinococcus multilocularis | serine:threonine protein kinase 12 B | 0.0661 | 0.1043 | 0.1491 |
Schistosoma mansoni | septate junction protein | 0.0052 | 0.0018 | 0.0016 |
Schistosoma mansoni | hypothetical protein | 0.0268 | 0.0381 | 0.038 |
Schistosoma mansoni | receptor tyrosine phosphatase type r2a | 0.0055 | 0.0024 | 0.0022 |
Mycobacterium tuberculosis | Probable cytochrome P450 130 Cyp130 | 0.0268 | 0.0381 | 0.5 |
Mycobacterium tuberculosis | Probable cytochrome P450 monooxygenase 142 Cyp142 | 0.0268 | 0.0381 | 0.5 |
Mycobacterium tuberculosis | Probable cytochrome P450 137 Cyp137 | 0.0268 | 0.0381 | 0.5 |
Entamoeba histolytica | serine/threonine- protein kinase 6 , putative | 0.0661 | 0.1043 | 0.3506 |
Echinococcus granulosus | neuroglian | 0.0265 | 0.0376 | 0.0536 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.019 | 0.025 | 0.0842 |
Loa Loa (eye worm) | hypothetical protein | 0.0243 | 0.0339 | 0.1141 |
Toxoplasma gondii | cytochrome p450 superfamily protein | 0.0268 | 0.0381 | 0.3644 |
Mycobacterium tuberculosis | Probable cytochrome P450 138 Cyp138 | 0.0268 | 0.0381 | 0.5 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S10 | 0.054 | 0.0839 | 0.2818 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0018 | 0.006 |
Mycobacterium tuberculosis | Probable cytochrome P450 143 Cyp143 | 0.0268 | 0.0381 | 0.5 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.019 | 0.025 | 0.0356 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0046 | 0.0008 | 0.0007 |
Brugia malayi | cytochrome P450 | 0.0268 | 0.0381 | 0.1283 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0052 | 0.0018 | 0.006 |
Leishmania major | serine carboxypeptidase (CBP1), putative,serine peptidase, Clan SC, Family S10 | 0.054 | 0.0839 | 0.2818 |
Mycobacterium tuberculosis | Probable cytochrome P450 123 Cyp123 | 0.0268 | 0.0381 | 0.5 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0055 | 0.0024 | 0.008 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0439 | 0.067 | 0.225 |
Mycobacterium tuberculosis | Probable cytochrome P450 144 Cyp144 | 0.0268 | 0.0381 | 0.5 |
Plasmodium vivax | serine/threonine protein kinase 6, putative | 0.0661 | 0.1043 | 0.5 |
Trichomonas vaginalis | CAMK family protein kinase | 0.1808 | 0.2973 | 1 |
Loa Loa (eye worm) | cytochrome P450 | 0.0268 | 0.0381 | 0.1283 |
Echinococcus multilocularis | tyrosine protein kinase otk | 0.0052 | 0.0018 | 0.0023 |
Echinococcus multilocularis | aurora kinase A | 0.0661 | 0.1043 | 0.1491 |
Trypanosoma brucei | polo-like protein kinase | 0.1808 | 0.2973 | 1 |
Schistosoma mansoni | nephrin | 0.0268 | 0.0382 | 0.038 |
Echinococcus granulosus | basic fibroblast growth factor receptor 1 A | 0.0121 | 0.0135 | 0.019 |
Echinococcus granulosus | lachesin | 0.0052 | 0.0018 | 0.0023 |
Brugia malayi | hypothetical protein | 0.0312 | 0.0456 | 0.1534 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.019 | 0.025 | 0.0842 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0055 | 0.0024 | 0.008 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.1469 | 0.2403 | 0.8086 |
Echinococcus multilocularis | Serine:threonine protein kinase PLK4 | 0.4193 | 0.6987 | 1 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S10 | 0.054 | 0.0839 | 0.2818 |
Loa Loa (eye worm) | hypothetical protein | 0.0243 | 0.0339 | 0.1141 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0042 | 0.0002 | 0.0007 |
Mycobacterium tuberculosis | Probable cytochrome P450 139 Cyp139 | 0.0268 | 0.0381 | 0.5 |
Loa Loa (eye worm) | TK/ROR protein kinase | 0.0049 | 0.0014 | 0.0048 |
Echinococcus multilocularis | neuroglian | 0.0265 | 0.0376 | 0.0536 |
Schistosoma mansoni | nephrin | 0.0055 | 0.0024 | 0.0022 |
Loa Loa (eye worm) | TK protein kinase | 0.0147 | 0.0178 | 0.0598 |
Brugia malayi | Cytochrome P450 family protein | 0.0439 | 0.067 | 0.2255 |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.022 | 0.074 |
Echinococcus multilocularis | roundabout 2 | 0.0294 | 0.0426 | 0.0607 |
Leishmania major | cytochrome p450-like protein | 0.0268 | 0.0381 | 0.1277 |
Mycobacterium tuberculosis | Probable cytochrome P450 140 Cyp140 | 0.0268 | 0.0381 | 0.5 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0538 | 0.0837 | 0.1196 |
Trichomonas vaginalis | CAMK family protein kinase | 0.1808 | 0.2973 | 1 |
Brugia malayi | Cytochrome P450 family protein | 0.0268 | 0.0381 | 0.1283 |
Mycobacterium tuberculosis | Probable cytochrome P450 128 Cyp128 | 0.0268 | 0.0381 | 0.5 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase | 0.0055 | 0.0024 | 0.0031 |
Echinococcus granulosus | serine:threonine protein kinase 12 B | 0.0661 | 0.1043 | 0.1491 |
Trypanosoma cruzi | cytochrome p450-like protein, putative | 0.0268 | 0.0381 | 0.1277 |
Onchocerca volvulus | Basement membrane proteoglycan homolog | 0.0052 | 0.0018 | 0.0032 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.1808 | 0.2973 | 1 |
Onchocerca volvulus | Tyrosine kinase homolog | 0.123 | 0.2001 | 0.6721 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0018 | 0.006 |
Echinococcus multilocularis | twitchin | 0.0042 | 0.0003 | 0.0001 |
Schistosoma mansoni | titin | 0.0046 | 0.0008 | 0.0007 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0268 | 0.0381 | 0.1277 |
Schistosoma mansoni | neuroglian | 0.0055 | 0.0024 | 0.0022 |
Schistosoma mansoni | alpha-glucosidase | 0.0163 | 0.0206 | 0.0204 |
Trypanosoma cruzi | serine peptidase, Clan SC, Family S10, putative | 0.054 | 0.0839 | 0.2818 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.1808 | 0.2973 | 1 |
Brugia malayi | Prion-like- | 0.0052 | 0.0018 | 0.006 |
Entamoeba histolytica | protein kinase , putative | 0.0661 | 0.1043 | 0.3506 |
Mycobacterium leprae | Conserved hypothetical protein | 0.0268 | 0.0381 | 0.5 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0055 | 0.0024 | 0.008 |
Echinococcus multilocularis | titin | 0.0046 | 0.0008 | 0.0009 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.0055 | 0.0024 | 0.0031 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S10 | 0.054 | 0.0839 | 0.2818 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.019 | 0.025 | 0.0356 |
Mycobacterium tuberculosis | Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) | 0.0268 | 0.0381 | 0.5 |
Trichomonas vaginalis | CAMK family protein kinase | 0.1808 | 0.2973 | 1 |
Loa Loa (eye worm) | TK/KIN16 protein kinase | 0.1469 | 0.2403 | 0.8086 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0018 | 0.006 |
Schistosoma mansoni | cell adhesion molecule | 0.0269 | 0.0383 | 0.0381 |
Echinococcus multilocularis | neuroglian | 0.0055 | 0.0024 | 0.0031 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase | 0.0055 | 0.0024 | 0.0031 |
Trichomonas vaginalis | CAMK family protein kinase | 0.1808 | 0.2973 | 1 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0052 | 0.0018 | 0.006 |
Leishmania major | lanosterol 14-alpha-demethylase, putative | 0.0268 | 0.0381 | 0.1277 |
Trichomonas vaginalis | AGC family protein kinase | 0.0661 | 0.1043 | 0.3506 |
Echinococcus granulosus | Immunoglobulin | 0.0239 | 0.0333 | 0.0474 |
Echinococcus multilocularis | lysosomal protective protein | 0.054 | 0.0839 | 0.1199 |
Schistosoma mansoni | family S10 unassigned peptidase (S10 family) | 0.054 | 0.0839 | 0.0837 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
GI50 (functional) | -7.516 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.437 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.291 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.