Detailed information for compound 1654261

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 594.697 | Formula: C36H38N2O6
  • H donors: 2 H acceptors: 1 LogP: 5.87 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 2
  • SMILES: COc1cc2[C@H]3Cc4ccc(c(c4)Oc4ccc(C[C@@H]5c6cc(Oc(c1O)c2CCN3C)c(OC)cc6CCN5)cc4)OC
  • InChi: 1S/C36H38N2O6/c1-38-14-12-25-27-20-34(42-4)35(39)36(25)44-33-19-26-23(18-31(33)41-3)11-13-37-28(26)15-21-5-8-24(9-6-21)43-32-17-22(16-29(27)38)7-10-30(32)40-2/h5-10,17-20,28-29,37,39H,11-16H2,1-4H3/t28-,29-/m1/s1
  • InChiKey: KDAKERGIGVRSPM-FQLXRVMXSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) tyrosinase 1 0.0685 1 1
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0043 0.0378 0.0774
Loa Loa (eye worm) hypothetical protein 0.0038 0.0296 0.0296
Loa Loa (eye worm) hypothetical protein 0.004 0.0332 0.0332
Loa Loa (eye worm) hypothetical protein 0.0019 0.0017 0.0017
Mycobacterium tuberculosis Conserved protein 0.0038 0.0296 0.0863
Schistosoma mansoni tyrosinase precursor 0.0685 1 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.0682 0.3706
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0037 0.0294 0.0602
Brugia malayi Common central domain of tyrosinase family protein 0.0685 1 1
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0017 0.0018
Loa Loa (eye worm) ShTK domain-containing protein 0.0685 1 1
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.0685 1 1
Schistosoma mansoni hypothetical protein 0.0038 0.0306 0.0306
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0043 0.0378 1
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0017 0.0196
Echinococcus multilocularis polycomb protein SCMH1 0.005 0.0478 0.0977
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0261 0.0534
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.4012 1
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0063 0.0682 0.1397
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0038 0.0296 0.0863
Loa Loa (eye worm) transcription factor SMAD2 0.0135 0.1754 0.1754
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0139 0.1824 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.4012 1
Echinococcus granulosus polycomb protein SCMH1 0.005 0.0478 0.0977
Loa Loa (eye worm) hypothetical protein 0.0685 1 1
Loa Loa (eye worm) mbt repeat family protein 0.005 0.0478 0.0478
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0139 0.1824 0.5469
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.0685 1 1
Loa Loa (eye worm) MH2 domain-containing protein 0.0135 0.1754 0.1754
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0063 0.0682 0.2027
Schistosoma mansoni ap endonuclease 0.0018 0.001 0.001
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.0378 0.0919
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0017 0.0196
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.4012 1
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0018 0.001 0.5
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.0685 1 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0017 0.0196
Mycobacterium ulcerans esterase/lipase LipP 0.0038 0.0296 0.1578
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0296 0.0715
Echinococcus granulosus tumor protein p63 0.0344 0.4885 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.4012 1
Echinococcus granulosus SAM and MBT domain containing protein 0.005 0.0478 0.0977
Mycobacterium tuberculosis Conserved protein 0.0038 0.0296 0.0863
Trichomonas vaginalis esterase, putative 0.0038 0.0296 0.0715
Loa Loa (eye worm) hypothetical protein 0.0056 0.058 0.058
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0096 0.1179 0.117
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0017 0.0196
Giardia lamblia DINP protein human, muc B family 0.0019 0.0017 0.0018
Echinococcus granulosus dna polymerase eta 0.0019 0.0017 0.0036
Schistosoma mansoni hypothetical protein 0.0021 0.0056 0.0056
Brugia malayi beta-lactamase family protein 0.0038 0.0296 0.0287
Loa Loa (eye worm) hypothetical protein 0.0042 0.0369 0.0369
Schistosoma mansoni hypothetical protein 0.0035 0.0261 0.0261
Treponema pallidum fructose-bisphosphate aldolase 0.0285 0.4012 1
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0017 0.0036
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0296 0.0715
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0296 0.0715
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0096 0.1179 0.1179
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0017 0.0018
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.001 0.0021
Leishmania major DNA polymerase kappa, putative 0.0019 0.0017 0.0107
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0017 0.0196
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.005 0.0478 0.0187
Schistosoma mansoni aldehyde dehydrogenase 0.0063 0.0682 0.0682
Mycobacterium ulcerans hypothetical protein 0.0038 0.0296 0.1578
Schistosoma mansoni bromodomain containing protein 0.0066 0.0721 0.0721
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0017 0.0017
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0063 0.0682 0.1397
Schistosoma mansoni aldehyde dehydrogenase 0.0063 0.0682 0.0682
Onchocerca volvulus 0.0685 1 1
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0038 0.0296 0.0296
Mycobacterium ulcerans beta-lactamase 0.0038 0.0296 0.1578
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0023 0.0086 0.0175
Loa Loa (eye worm) hypothetical protein 0.0038 0.0306 0.0306
Mycobacterium tuberculosis Conserved protein 0.0038 0.0296 0.0863
Loa Loa (eye worm) ShTK domain-containing protein 0.0685 1 1
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0038 0.0296 0.0863
Toxoplasma gondii aldehyde dehydrogenase 0.0063 0.0682 1
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0038 0.0296 0.1578
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0017 0.0017
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0285 0.4012 1
Onchocerca volvulus Huntingtin homolog 0.0137 0.1788 0.1538
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0285 0.4012 1
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0063 0.0682 1
Onchocerca volvulus Huntingtin homolog 0.0137 0.1788 0.1538
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0017 0.0196
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.0682 0.3706
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0017 0.0107
Schistosoma mansoni hypothetical protein 0.0305 0.4309 0.4309
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0296 0.0296
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0017 0.0017
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0096 0.1179 0.1179
Entamoeba histolytica hypothetical protein 0.0035 0.0261 0.0626
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0096 0.1179 0.2414
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0062 0.0665 0.1361
Giardia lamblia Fructose-bisphosphate aldolase 0.0285 0.4012 1
Brugia malayi MH2 domain containing protein 0.0135 0.1754 0.1746
Echinococcus multilocularis dna polymerase eta 0.0019 0.0017 0.0036
Echinococcus multilocularis zinc finger protein 0.002 0.0039 0.0081
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0056 0.057 0.057
Echinococcus multilocularis SAM and MBT domain containing protein 0.005 0.0478 0.0977
Leishmania major DNA polymerase eta, putative 0.0019 0.0017 0.0107
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0017 0.0196
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0043 0.0378 0.0774
Brugia malayi mbt repeat family protein 0.005 0.0478 0.0468
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0043 0.0378 0.0368
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0261 0.0261
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.4012 1
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0296 0.7783
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.0378 0.0919
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0199 0.2719 0.5566
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0038 0.0296 0.0863
Loa Loa (eye worm) hypothetical protein 0.0038 0.0296 0.0296
Loa Loa (eye worm) bromodomain containing protein 0.0018 0.001 0.001
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0062 0.0665 0.1361
Echinococcus multilocularis histone acetyltransferase MYST2 0.0056 0.058 0.1188
Schistosoma mansoni ap endonuclease 0.0018 0.001 0.001
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0017 0.0196
Mycobacterium tuberculosis Probable lipase LipD 0.0038 0.0296 0.0863
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0017 0.0007
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0017 0.0196
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0038 0.0296 0.0296
Loa Loa (eye worm) hypothetical protein 0.0685 1 1
Echinococcus granulosus ubiquitin specific protease 41 0.0043 0.0378 0.0774
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0096 0.1179 0.2414
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.4012 1
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0017 0.0196
Entamoeba histolytica hypothetical protein 0.0035 0.0261 0.0626
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0043 0.0378 0.0919
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0017 0.0196
Brugia malayi Bromodomain containing protein 0.0078 0.0903 0.0894
Toxoplasma gondii ABC1 family protein 0.0038 0.0296 0.4258
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0056 0.058 0.0571
Entamoeba histolytica hypothetical protein 0.0035 0.0261 0.0626
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0038 0.0296 0.0287
Leishmania major hypothetical protein, conserved 0.0038 0.0296 0.4258
Echinococcus granulosus histone acetyltransferase MYST2 0.0056 0.058 0.1188
Schistosoma mansoni zinc finger protein 0.002 0.0039 0.0039
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0043 0.0378 0.0774
Loa Loa (eye worm) hypothetical protein 0.0038 0.0296 0.0296
Brugia malayi Calcitonin receptor-like protein seb-1 0.0056 0.057 0.056
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0017 0.0036
Schistosoma mansoni sex comb on midleg homolog 0.005 0.0478 0.0478
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0139 0.1824 1
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0261 0.0534
Mycobacterium tuberculosis Probable lipase LipE 0.0038 0.0296 0.0863
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0296 0.0715
Mycobacterium tuberculosis Probable hydrolase 0.0038 0.0296 0.0863
Schistosoma mansoni sex comb on midleg homolog 0.005 0.0478 0.0478
Loa Loa (eye worm) MBCTL1 0.0056 0.058 0.058
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0378 0.0919
Brugia malayi hypothetical protein 0.0137 0.1788 0.178
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0017 0.0022
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0056 0.058 0.1188
Brugia malayi latrophilin 2 splice variant baaae 0.0038 0.0306 0.0296
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0043 0.0378 0.0919
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0296 0.7783
Schistosoma mansoni cellular tumor antigen P53 0.005 0.0488 0.0488
Echinococcus granulosus dna polymerase kappa 0.0019 0.0017 0.0036
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0017 0.0196
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0199 0.2719 0.5566
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.0296 0.7783
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0017 0.0007
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.001 0.5
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0096 0.1179 0.1179
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0017 0.0196
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0096 0.1179 0.1179
Schistosoma mansoni myelin transcription factor 1 myt1 0.0056 0.058 0.058
Onchocerca volvulus 0.0685 1 1
Echinococcus multilocularis ubiquitin specific protease 41 0.0043 0.0378 0.0774
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0017 0.0018
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0017 0.0196
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0043 0.0378 0.0774
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0017 0.004
Echinococcus multilocularis tumor protein p63 0.0344 0.4885 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0296 0.0296
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0017 0.004
Echinococcus granulosus fetal alzheimer antigen falz 0.0023 0.0086 0.0175
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0096 0.1179 0.2414
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0017 0.0196
Entamoeba histolytica hypothetical protein 0.0035 0.0261 0.0626
Onchocerca volvulus 0.0685 1 1
Mycobacterium ulcerans lipase LipD 0.0038 0.0296 0.1578
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0017 0.0196
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.001 0.0021
Onchocerca volvulus 0.005 0.0488 0.0198
Loa Loa (eye worm) hypothetical protein 0.0137 0.1788 0.1788
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0037 0.0294 0.0602
Loa Loa (eye worm) hypothetical protein 0.005 0.0488 0.0488
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0043 0.0378 0.5471
Loa Loa (eye worm) hypothetical protein 0.0137 0.1788 0.1788
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0043 0.0378 0.0378
Loa Loa (eye worm) hypothetical protein 0.0038 0.0296 0.0296
Echinococcus multilocularis beta LACTamase domain containing family member 0.0038 0.0296 0.0607
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0296 0.0296
Loa Loa (eye worm) hypothetical protein 0.0056 0.057 0.057
Mycobacterium tuberculosis Probable esterase LipL 0.0038 0.0296 0.0863
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.4012 1
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0296 1
Brugia malayi mbt repeat family protein 0.005 0.0478 0.0468
Schistosoma mansoni DNA polymerase eta 0.0019 0.0017 0.0017
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0096 0.1179 0.2414
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0017 0.0022
Echinococcus granulosus zinc finger protein 0.002 0.0039 0.0081
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0043 0.0378 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0296 0.0715
Brugia malayi Bromodomain containing protein 0.004 0.0331 0.0321
Loa Loa (eye worm) hypothetical protein 0.0043 0.0378 0.0378
Brugia malayi beta-lactamase family protein 0.0038 0.0296 0.0287
Onchocerca volvulus 0.0685 1 1
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0056 0.058 0.1188
Loa Loa (eye worm) hypothetical protein 0.0074 0.0837 0.0837
Echinococcus granulosus beta LACTamase domain containing family member 0.0038 0.0296 0.0607
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0017 0.0036
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0056 0.0056
Brugia malayi PHD-finger family protein 0.0026 0.0122 0.0112
Trypanosoma brucei unspecified product 0.0019 0.0017 0.0196
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0017 0.0196
Brugia malayi beta-lactamase 0.0038 0.0296 0.0287
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0043 0.0378 1
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0023 0.0086 0.0086
Onchocerca volvulus 0.005 0.0478 0.0187
Schistosoma mansoni tyrosinase precursor 0.0685 1 1
Loa Loa (eye worm) hypothetical protein 0.005 0.0478 0.0478
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0017 0.0196
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0056 0.057 0.056
Brugia malayi hypothetical protein 0.0035 0.0261 0.0251
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.0682 0.3706
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0017 0.0196
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0043 0.0378 0.0378
Mycobacterium tuberculosis Possible penicillin-binding protein 0.024 0.3326 1
Loa Loa (eye worm) beta-lactamase 0.0038 0.0296 0.0296
Loa Loa (eye worm) hypothetical protein 0.0044 0.0399 0.0399
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0285 0.4012 1
Brugia malayi Hypothetical tyrosinase-like protein F21C3.2 in chromosome I 0.0685 1 1
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.005 0.0478 0.0478

Activities

Activity type Activity value Assay description Source Reference
MED (functional) = 12 uM Induction of rat C/EBPalpha expression transfected in human U937 cells after 24 hrs by luciferase reporter gene assay relative to ATRA ChEMBL. 22766217

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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