Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | animal heme peroxidase | 0.0484 | 0.1737 | 0.1737 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0012 | 0.0022 | 0.0022 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0012 | 0.0022 | 0.0022 |
Plasmodium falciparum | DNA topoisomerase VI, b subunit, putative | 0.0055 | 0.018 | 0.0303 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0075 | 0.0254 | 0.0227 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0278 | 0.0989 | 0.3328 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0022 | 0.0022 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0278 | 0.0989 | 0.0964 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0278 | 0.0989 | 0.0989 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0484 | 0.1737 | 0.1737 |
Mycobacterium ulcerans | dehydrogenase | 0.0074 | 0.0248 | 0.2386 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0012 | 0.0022 | 0.0127 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.2761 | 1 | 1 |
Onchocerca volvulus | 0.0041 | 0.0129 | 0.0744 | |
Echinococcus multilocularis | geminin | 0.0387 | 0.1385 | 0.1385 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0278 | 0.0989 | 0.0964 |
Trichomonas vaginalis | glutamate synthase, putative | 0.0074 | 0.0248 | 0.2386 |
Trypanosoma brucei | heat shock protein, putative | 0.0055 | 0.018 | 0.0153 |
Loa Loa (eye worm) | TOPoisomerase family member | 0.0055 | 0.018 | 0.018 |
Onchocerca volvulus | Protein cereblon homolog | 0.0342 | 0.122 | 0.7012 |
Loa Loa (eye worm) | hypothetical protein | 0.0484 | 0.1737 | 0.1737 |
Trichomonas vaginalis | apoptosis inducing factor, putative | 0.0074 | 0.0248 | 0.2386 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0012 | 0.0022 | 0.0022 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0012 | 0.0022 | 0.0022 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0041 | 0.0129 | 0.0129 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0075 | 0.0254 | 0.0227 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0051 | 0.0051 |
Loa Loa (eye worm) | hypothetical protein | 0.0006 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0017 | 0.0017 |
Mycobacterium ulcerans | ferredoxin reductase | 0.0074 | 0.0248 | 0.2386 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0012 | 0.0022 | 0.0022 |
Plasmodium vivax | NAD(P)H-dependent glutamate synthase, putative | 0.0074 | 0.0248 | 0.0729 |
Trypanosoma cruzi | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative | 0.0055 | 0.018 | 0.0153 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0204 | 0.0721 | 0.0721 |
Schistosoma mansoni | hypothetical protein | 0.0342 | 0.122 | 0.122 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0012 | 0.0022 | 0.0022 |
Mycobacterium ulcerans | two component sensor histidine kinase SenX3 | 0.0055 | 0.018 | 0.1688 |
Leishmania major | 2,4-dienoyl-coa reductase fadh1, putative | 0.0074 | 0.0248 | 0.0221 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0044 | 0.0139 | 0.0139 |
Echinococcus multilocularis | carbonic anhydrase | 0.1495 | 0.5406 | 0.5406 |
Echinococcus multilocularis | protein cereblon | 0.0342 | 0.122 | 0.122 |
Echinococcus multilocularis | peroxidasin | 0.0484 | 0.1737 | 0.1737 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0022 | 0.0022 |
Plasmodium falciparum | glutathione reductase | 0.0802 | 0.289 | 0.5332 |
Plasmodium vivax | heat shock protein 86, putative | 0.0055 | 0.018 | 0.0491 |
Mycobacterium ulcerans | hypothetical protein | 0.0074 | 0.0248 | 0.2386 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.1495 | 0.5406 | 0.5406 |
Schistosoma mansoni | glutamate synthase | 0.0074 | 0.0248 | 0.0248 |
Plasmodium vivax | glutathione reductase, putative | 0.0802 | 0.289 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0022 | 0.0022 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0278 | 0.0989 | 0.0964 |
Brugia malayi | Animal haem peroxidase family protein | 0.0484 | 0.1737 | 0.1737 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0278 | 0.0989 | 0.0989 |
Echinococcus granulosus | dihydropyrimidine dehydrogenase NADP | 0.0074 | 0.0248 | 0.0248 |
Echinococcus granulosus | carbonic anhydrase | 0.1495 | 0.5406 | 0.5406 |
Trypanosoma brucei | heat shock protein, putative | 0.0055 | 0.018 | 0.0153 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0074 | 0.0248 | 0.0807 |
Giardia lamblia | Glycerol-3-phosphate dehydrogenase | 0.0074 | 0.0248 | 0.2386 |
Mycobacterium ulcerans | hypothetical protein | 0.0041 | 0.0129 | 0.1168 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0074 | 0.0248 | 0.2386 |
Brugia malayi | nuclear receptor NHR-88 | 0.0012 | 0.0022 | 0.0022 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0278 | 0.0989 | 0.0964 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0006 | 0.0002 | 0.0002 |
Schistosoma mansoni | thyroid hormone receptor | 0.0155 | 0.0544 | 0.0544 |
Mycobacterium tuberculosis | Possible two component sensor kinase TcrY | 0.0055 | 0.018 | 0.0571 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0278 | 0.0989 | 0.3384 |
Mycobacterium leprae | PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) | 0.0074 | 0.0248 | 0.1378 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.1495 | 0.5406 | 0.5406 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0006 | 0.0002 | 0.0002 |
Leishmania major | hypothetical protein, conserved | 0.0055 | 0.018 | 0.0153 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.0074 | 0.0248 | 0.2386 |
Mycobacterium ulcerans | two component system response phosphate sensor kinase, PhoR | 0.0055 | 0.018 | 0.1688 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0041 | 0.0129 | 0.0102 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0074 | 0.0248 | 0.2386 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0041 | 0.0129 | 0.0129 |
Schistosoma mansoni | disulfide oxidoreductase | 0.0074 | 0.0248 | 0.0248 |
Loa Loa (eye worm) | hypothetical protein | 0.0484 | 0.1737 | 0.1737 |
Onchocerca volvulus | Peroxidase homolog | 0.0484 | 0.1737 | 0.9988 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0129 | 0.0129 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.0074 | 0.0248 | 0.2386 |
Toxoplasma gondii | pyridine nucleotide-disulfide oxidoreductase domain-containing protein | 0.0074 | 0.0248 | 0.0429 |
Schistosoma mansoni | pyruvate dehydrogenase | 0.0935 | 0.3372 | 0.3372 |
Mycobacterium leprae | THIOREDOXIN TRXC (TRX) (MPT46) | 0.0074 | 0.0248 | 0.1378 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0278 | 0.0989 | 0.1803 |
Loa Loa (eye worm) | hypothetical protein | 0.1495 | 0.5406 | 0.5406 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0074 | 0.0248 | 0.0807 |
Trypanosoma brucei | pyridine nucleotide-disulphide oxidoreductase, putative | 0.0074 | 0.0248 | 0.0221 |
Chlamydia trachomatis | thioredoxin reductase | 0.0074 | 0.0248 | 0.0839 |
Trichomonas vaginalis | dihydrolipoamide dehydrogenase, putative | 0.0074 | 0.0248 | 0.2386 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0155 | 0.0544 | 0.0544 |
Brugia malayi | heat shock protein 90 | 0.0055 | 0.018 | 0.018 |
Brugia malayi | hypothetical protein | 0.0006 | 0.0002 | 0.0002 |
Mycobacterium tuberculosis | Conserved protein | 0.0041 | 0.0129 | 0.0395 |
Mycobacterium tuberculosis | DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) | 0.0055 | 0.018 | 0.0571 |
Mycobacterium ulcerans | two component sensory transduction histidine kinase MtrB | 0.0055 | 0.018 | 0.1688 |
Onchocerca volvulus | 0.0074 | 0.0248 | 0.1425 | |
Trypanosoma brucei | pyruvate dehydrogenase (lipoamide) kinase, putative | 0.0346 | 0.1236 | 0.1212 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.018 | 0.0153 |
Loa Loa (eye worm) | hypothetical protein | 0.0484 | 0.1737 | 0.1737 |
Mycobacterium tuberculosis | Conserved protein | 0.0055 | 0.018 | 0.0571 |
Leishmania major | hypothetical protein, conserved | 0.0041 | 0.0129 | 0.0102 |
Loa Loa (eye worm) | endoplasmin | 0.0055 | 0.018 | 0.018 |
Trypanosoma brucei | NADPH:adrenodoxin oxidoreductase, mitochondrial, putative | 0.0074 | 0.0248 | 0.0221 |
Entamoeba histolytica | dihydropyrimidine dehydrogenase, putative | 0.0074 | 0.0248 | 0.1849 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0041 | 0.0129 | 0.0129 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0041 | 0.0129 | 0.1168 |
Brugia malayi | Probable DNA topoisomerase II | 0.0055 | 0.018 | 0.018 |
Echinococcus granulosus | bloom syndrome protein | 0.0024 | 0.0069 | 0.0069 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0278 | 0.0989 | 0.0964 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0075 | 0.0254 | 0.0254 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.018 | 0.0153 |
Loa Loa (eye worm) | hypothetical protein | 0.0006 | 0.0002 | 0.0002 |
Trypanosoma cruzi | 2,4-dienoyl-coa reductase fadh1, putative | 0.0074 | 0.0248 | 0.0221 |
Brugia malayi | Animal haem peroxidase family protein | 0.0484 | 0.1737 | 0.1737 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.018 | 0.018 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.018 | 0.0153 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0074 | 0.0248 | 0.0807 |
Plasmodium falciparum | ferrodoxin reductase-like protein | 0.0074 | 0.0248 | 0.0429 |
Loa Loa (eye worm) | hypothetical protein | 0.0484 | 0.1737 | 0.1737 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0016 | 0.0016 |
Echinococcus multilocularis | carbonic anhydrase | 0.1495 | 0.5406 | 0.5406 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0075 | 0.0254 | 0.0254 |
Brugia malayi | nuclear hormone receptor | 0.0012 | 0.0022 | 0.0022 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0012 | 0.0022 | 0.0022 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0022 | 0.0022 |
Echinococcus multilocularis | DNA topoisomerase 2 alpha | 0.0055 | 0.018 | 0.018 |
Mycobacterium ulcerans | NADH dehydrogenase Ndh1 | 0.0074 | 0.0248 | 0.2386 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0278 | 0.0989 | 0.1803 |
Giardia lamblia | Heat shock protein HSP 90-alpha | 0.0055 | 0.018 | 0.1688 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0278 | 0.0989 | 0.3328 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0278 | 0.0989 | 0.1803 |
Onchocerca volvulus | Dual oxidase homolog | 0.0484 | 0.1737 | 0.9988 |
Schistosoma mansoni | thyroid hormone receptor | 0.0155 | 0.0544 | 0.0544 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.018 | 0.0153 |
Mycobacterium ulcerans | NADH dehydrogenase Ndh | 0.0074 | 0.0248 | 0.2386 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0006 | 0.0002 | 0.0002 |
Mycobacterium leprae | PUTATIVE TWO COMPONENT SENSOR HISTIDINE KINASE SENX3 | 0.0055 | 0.018 | 0.0588 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0129 | 0.0129 |
Entamoeba histolytica | heat shock protein 90, putative | 0.0055 | 0.018 | 0.128 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0278 | 0.0989 | 1 |
Brugia malayi | glutathione reductase | 0.0802 | 0.289 | 0.289 |
Wolbachia endosymbiont of Brugia malayi | NADPH-dependent glutamate synthase beta chain | 0.0074 | 0.0248 | 0.0839 |
Leishmania major | developmentally regulated phosphoprotein-like protein | 0.099 | 0.3572 | 0.3554 |
Trypanosoma brucei | trypanothione reductase | 0.0802 | 0.289 | 0.2871 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0278 | 0.0989 | 1 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0074 | 0.0248 | 0.2386 |
Plasmodium falciparum | endoplasmin, putative | 0.0055 | 0.018 | 0.0303 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0041 | 0.0129 | 0.0395 |
Trichomonas vaginalis | esterase, putative | 0.0041 | 0.0129 | 0.1168 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0074 | 0.0248 | 0.1378 |
Brugia malayi | NADPH:adrenodoxin oxidoreductase, mitochondrial precursor | 0.0074 | 0.0248 | 0.0248 |
Echinococcus granulosus | carbonic anhydrase | 0.1495 | 0.5406 | 0.5406 |
Mycobacterium leprae | Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate | 0.0074 | 0.0248 | 0.1378 |
Mycobacterium ulcerans | two component sensor histidine kinase PrrB | 0.0055 | 0.018 | 0.1688 |
Onchocerca volvulus | Peroxidasin homolog | 0.0484 | 0.1737 | 0.9988 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0012 | 0.0022 | 0.0022 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0012 | 0.0022 | 0.0022 |
Wolbachia endosymbiont of Brugia malayi | thioredoxin reductase | 0.0074 | 0.0248 | 0.0839 |
Schistosoma mansoni | peroxidasin | 0.0484 | 0.1737 | 0.1737 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0012 | 0.0022 | 0.0022 |
Mycobacterium ulcerans | two component regulator - sensor kinase | 0.0055 | 0.018 | 0.1688 |
Brugia malayi | Animal haem peroxidase family protein | 0.0484 | 0.1737 | 0.1737 |
Plasmodium vivax | ferrodoxin reductase, putative | 0.0074 | 0.0248 | 0.0729 |
Echinococcus multilocularis | dihydropyrimidine dehydrogenase (NADP+) | 0.0074 | 0.0248 | 0.0248 |
Brugia malayi | Protein kinase domain containing protein | 0.0062 | 0.0205 | 0.0205 |
Mycobacterium ulcerans | two component sensor histidine kinase DevS | 0.0055 | 0.018 | 0.1688 |
Toxoplasma gondii | selenide, water dikinase | 0.0074 | 0.0248 | 0.0429 |
Schistosoma mansoni | hypothetical protein | 0.0144 | 0.0502 | 0.0502 |
Wolbachia endosymbiont of Brugia malayi | thioredoxin reductase | 0.0074 | 0.0248 | 0.0839 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0278 | 0.0989 | 1 |
Toxoplasma gondii | pyruvate dehydrogenase kinase, putative | 0.0346 | 0.1236 | 0.2262 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0144 | 0.0502 | 0.0502 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0012 | 0.0022 | 0.0022 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0278 | 0.0989 | 0.3384 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0074 | 0.0248 | 0.2386 |
Mycobacterium ulcerans | glutamate synthase subunit beta | 0.0074 | 0.0248 | 0.2386 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0278 | 0.0989 | 0.0964 |
Brugia malayi | Peroxidasin | 0.0484 | 0.1737 | 0.1737 |
Echinococcus granulosus | DNA topoisomerase 2 alpha | 0.0055 | 0.018 | 0.018 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0041 | 0.0129 | 0.1168 |
Trypanosoma brucei | heat shock protein 90, putative | 0.0055 | 0.018 | 0.0153 |
Brugia malayi | beta-lactamase family protein | 0.0041 | 0.0129 | 0.0129 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0278 | 0.0989 | 0.0964 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0012 | 0.0022 | 0.0022 |
Trypanosoma cruzi | developmentally regulated phosphoprotein, putative | 0.099 | 0.3572 | 0.3554 |
Trypanosoma brucei | DNA topoisomerase ii | 0.0055 | 0.018 | 0.0153 |
Echinococcus multilocularis | heat shock protein | 0.0055 | 0.018 | 0.018 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.018 | 0.0153 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0278 | 0.0989 | 0.3384 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.018 | 0.0153 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0012 | 0.0022 | 0.0022 |
Mycobacterium ulcerans | two component sensor histidine kinase TrcS | 0.0055 | 0.018 | 0.1688 |
Plasmodium vivax | type II NADH:ubiquinone oxidoreductase, putative | 0.0074 | 0.0248 | 0.0729 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0012 | 0.0022 | 0.0022 |
Echinococcus granulosus | heat shock protein | 0.0055 | 0.018 | 0.018 |
Echinococcus granulosus | FTZ F1 alpha | 0.0012 | 0.0022 | 0.0022 |
Trypanosoma brucei | heat shock protein, putative | 0.0055 | 0.018 | 0.0153 |
Entamoeba histolytica | DNA topoisomerase II, putative | 0.0055 | 0.018 | 0.128 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0012 | 0.0022 | 0.0022 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.2761 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0074 | 0.0248 | 0.0248 |
Toxoplasma gondii | thioredoxin reductase | 0.0802 | 0.289 | 0.5332 |
Loa Loa (eye worm) | pyridine nucleotide-disufhide oxidoreductase | 0.0074 | 0.0248 | 0.0248 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0075 | 0.0254 | 0.0227 |
Trypanosoma brucei | DNA topoisomerase II beta, putative | 0.0055 | 0.018 | 0.0153 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0075 | 0.0254 | 0.0254 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0022 | 0.0022 |
Leishmania major | hypothetical protein, conserved | 0.0074 | 0.0248 | 0.0221 |
Loa Loa (eye worm) | hypothetical protein | 0.0484 | 0.1737 | 0.1737 |
Loa Loa (eye worm) | hypothetical protein | 0.0484 | 0.1737 | 0.1737 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0075 | 0.0254 | 0.0254 |
Schistosoma mansoni | pyruvate dehydrogenase | 0.0935 | 0.3372 | 0.3372 |
Toxoplasma gondii | ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein | 0.0401 | 0.1436 | 0.2633 |
Trypanosoma brucei | heat shock protein, putative | 0.0055 | 0.018 | 0.0153 |
Plasmodium vivax | DNA topoisomerase II, putative | 0.0055 | 0.018 | 0.0491 |
Toxoplasma gondii | heat shock protein 90, putative | 0.0055 | 0.018 | 0.0303 |
Trypanosoma brucei | 2,4-dienoyl-coa reductase-like protein | 0.0074 | 0.0248 | 0.0221 |
Toxoplasma gondii | hypothetical protein | 0.1495 | 0.5406 | 1 |
Echinococcus granulosus | Pyruvate dehydrogenase lipoamide kinase | 0.099 | 0.3572 | 0.3572 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.018 | 0.0153 |
Mycobacterium ulcerans | two component sensor kinase MprB | 0.0055 | 0.018 | 0.1688 |
Mycobacterium ulcerans | NADPH:adrenodoxin oxidoreductase FprA | 0.0074 | 0.0248 | 0.2386 |
Loa Loa (eye worm) | hypothetical protein | 0.0006 | 0.0002 | 0.0002 |
Schistosoma mansoni | hypothetical protein | 0.1495 | 0.5406 | 0.5406 |
Schistosoma mansoni | nuclear hormone receptor | 0.0012 | 0.0022 | 0.0022 |
Loa Loa (eye worm) | hypothetical protein | 0.1495 | 0.5406 | 0.5406 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0012 | 0.0022 | 0.0022 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0012 | 0.0022 | 0.0022 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0012 | 0.0022 | 0.0022 |
Mycobacterium tuberculosis | Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) | 0.0074 | 0.0248 | 0.0807 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0278 | 0.0989 | 0.0964 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0041 | 0.0129 | 0.1168 |
Toxoplasma gondii | ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein | 0.0055 | 0.018 | 0.0303 |
Loa Loa (eye worm) | hypothetical protein | 0.0484 | 0.1737 | 0.1737 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0075 | 0.0254 | 0.1899 |
Brugia malayi | Endoplasmin precursor | 0.0055 | 0.018 | 0.018 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0012 | 0.0022 | 0.0022 |
Schistosoma mansoni | carbonic anhydrase-related | 0.1495 | 0.5406 | 0.5406 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0012 | 0.0022 | 0.0022 |
Schistosoma mansoni | DNA helicase recq5 | 0.001 | 0.0017 | 0.0017 |
Mycobacterium ulcerans | monoxygenase | 0.0074 | 0.0248 | 0.2386 |
Mycobacterium ulcerans | NADH dehydrogenase | 0.0074 | 0.0248 | 0.2386 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.018 | 0.0153 |
Schistosoma mansoni | sulfide quinone reductase | 0.0074 | 0.0248 | 0.0248 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0074 | 0.0248 | 0.0807 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.2761 | 1 | 1 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.2761 | 1 | 1 |
Echinococcus multilocularis | ATP dependent DNA helicase Q1 | 0.001 | 0.0017 | 0.0017 |
Loa Loa (eye worm) | hypothetical protein | 0.0484 | 0.1737 | 0.1737 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0041 | 0.0129 | 0.1168 |
Loa Loa (eye worm) | hypothetical protein | 0.0484 | 0.1737 | 0.1737 |
Brugia malayi | Putative carbonic anhydrase 5 precursor | 0.2761 | 1 | 1 |
Mycobacterium tuberculosis | Two component sensor histidine kinase TrcS | 0.0055 | 0.018 | 0.0571 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0074 | 0.0248 | 0.2386 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0278 | 0.0989 | 0.0964 |
Mycobacterium leprae | Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) | 0.0074 | 0.0248 | 0.1378 |
Echinococcus granulosus | geminin | 0.0387 | 0.1385 | 0.1385 |
Mycobacterium tuberculosis | Probable sensor protein KdpD | 0.0055 | 0.018 | 0.0571 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0012 | 0.0022 | 0.0022 |
Brugia malayi | hypothetical protein | 0.0484 | 0.1737 | 0.1737 |
Onchocerca volvulus | 0.0012 | 0.0022 | 0.0127 | |
Brugia malayi | hypothetical protein | 0.0342 | 0.122 | 0.122 |
Giardia lamblia | Sgs1 DNA helicase, putative | 0.001 | 0.0017 | 0.001 |
Loa Loa (eye worm) | RecQ helicase | 0.0024 | 0.0069 | 0.0069 |
Echinococcus multilocularis | Pyruvate dehydrogenase (lipoamide) kinase | 0.099 | 0.3572 | 0.3572 |
Trichomonas vaginalis | heat shock protein, putative | 0.0055 | 0.018 | 0.1688 |
Brugia malayi | Blistered cuticle protein 3 | 0.0484 | 0.1737 | 0.1737 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0074 | 0.0248 | 0.0221 |
Toxoplasma gondii | pyridine nucleotide-disulfide oxidoreductase domain-containing protein | 0.0074 | 0.0248 | 0.0429 |
Echinococcus multilocularis | bloom syndrome protein | 0.0024 | 0.0069 | 0.0069 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0278 | 0.0989 | 0.0964 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0204 | 0.0721 | 0.0721 |
Entamoeba histolytica | glutamate synthase beta subunit, putative | 0.0074 | 0.0248 | 0.1849 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.018 | 0.018 |
Toxoplasma gondii | NADH dehydrogenase (NDH2-II) | 0.0074 | 0.0248 | 0.0429 |
Trypanosoma brucei | DNA topoisomerase II alpha, putative | 0.0055 | 0.018 | 0.0153 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.018 | 0.0153 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0012 | 0.0022 | 0.0022 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.018 | 0.0153 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0006 | 0.0002 | 0.0002 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0041 | 0.0129 | 0.0129 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.018 | 0.0153 |
Entamoeba histolytica | heat shock protein 90, putative | 0.0055 | 0.018 | 0.128 |
Trichomonas vaginalis | sensory transduction histidine kinase bacterial, putative | 0.0055 | 0.018 | 0.1688 |
Entamoeba histolytica | NAD(FAD)-dependent dehydrogenase, putative | 0.0074 | 0.0248 | 0.1849 |
Trypanosoma brucei | heat shock protein, putative | 0.0055 | 0.018 | 0.0153 |
Mycobacterium tuberculosis | Probable reductase | 0.0074 | 0.0248 | 0.0807 |
Mycobacterium ulcerans | lipase LipD | 0.0041 | 0.0129 | 0.1168 |
Echinococcus granulosus | NADPH:adrenodoxin oxidoreductase | 0.0074 | 0.0248 | 0.0248 |
Onchocerca volvulus | Peroxidase homolog | 0.0484 | 0.1737 | 0.9988 |
Echinococcus granulosus | carbonic anhydrase II | 0.2761 | 1 | 1 |
Onchocerca volvulus | DNA topoisomerase 2 homolog | 0.0055 | 0.018 | 0.1035 |
Echinococcus multilocularis | carbonic anhydrase II | 0.2761 | 1 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0012 | 0.0022 | 0.0022 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0012 | 0.0022 | 0.0022 |
Onchocerca volvulus | 0.0484 | 0.1737 | 0.9988 | |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.1495 | 0.5406 | 0.5406 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0012 | 0.0022 | 0.0022 |
Echinococcus granulosus | peroxidasin | 0.0484 | 0.1737 | 0.1737 |
Trypanosoma brucei | heat shock protein, putative | 0.0055 | 0.018 | 0.0153 |
Brugia malayi | Thioredoxin reductase | 0.0802 | 0.289 | 0.289 |
Loa Loa (eye worm) | programmed cell death 8 | 0.0074 | 0.0248 | 0.0248 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0041 | 0.0129 | 0.1168 |
Trypanosoma brucei | developmentally regulated phosphoprotein | 0.099 | 0.3572 | 0.3554 |
Mycobacterium tuberculosis | Two component sensor kinase MprB | 0.0055 | 0.018 | 0.0571 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0041 | 0.0129 | 0.1168 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0024 | 0.0069 | 0.0543 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0012 | 0.0022 | 0.0022 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0012 | 0.0022 | 0.0022 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0248 | 0.0248 |
Plasmodium falciparum | DNA gyrase subunit B | 0.0055 | 0.018 | 0.0303 |
Brugia malayi | beta-lactamase family protein | 0.0041 | 0.0129 | 0.0129 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0012 | 0.0022 | 0.0022 |
Toxoplasma gondii | DNA topoisomerase 2, putative | 0.0055 | 0.018 | 0.0303 |
Echinococcus multilocularis | sulfide:quinone oxidoreductase | 0.0074 | 0.0248 | 0.0248 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0144 | 0.0502 | 0.0502 |
Toxoplasma gondii | non-proton pumping type-II NADH dehydrogenase I | 0.0074 | 0.0248 | 0.0429 |
Loa Loa (eye worm) | hypothetical protein | 0.0006 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0129 | 0.0129 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0012 | 0.0022 | 0.0022 |
Brugia malayi | DNA topoisomerase II, alpha isozyme | 0.0055 | 0.018 | 0.018 |
Trichomonas vaginalis | dihydropyrimidine dehydrogenase, putative | 0.0074 | 0.0248 | 0.2386 |
Mycobacterium leprae | TWO COMPONENT SENSOR HISTIDINE KINASE PRRB | 0.0055 | 0.018 | 0.0588 |
Schistosoma mansoni | coup transcription factor | 0.0012 | 0.0022 | 0.0022 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0012 | 0.0022 | 0.0127 |
Entamoeba histolytica | disulphide oxidoreductase, putative | 0.0074 | 0.0248 | 0.1849 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0022 | 0.0022 |
Leishmania major | hypothetical protein, conserved | 0.0074 | 0.0248 | 0.0221 |
Toxoplasma gondii | pyridine nucleotide-disulfide oxidoreductase domain-containing protein | 0.0074 | 0.0248 | 0.0429 |
Schistosoma mansoni | sulfide quinone reductase | 0.0074 | 0.0248 | 0.0248 |
Echinococcus granulosus | sulfide:quinone oxidoreductase | 0.0074 | 0.0248 | 0.0248 |
Echinococcus granulosus | leucine rich repeat serine:threonine protein | 0.0062 | 0.0206 | 0.0206 |
Schistosoma mansoni | peroxidasin | 0.0484 | 0.1737 | 0.1737 |
Brugia malayi | Animal haem peroxidase family protein | 0.0484 | 0.1737 | 0.1737 |
Echinococcus multilocularis | heat shock protein 90 | 0.0055 | 0.018 | 0.018 |
Schistosoma mansoni | DNA topoisomerase II | 0.0055 | 0.018 | 0.018 |
Mycobacterium ulcerans | DNA gyrase subunit B | 0.0055 | 0.018 | 0.1688 |
Plasmodium falciparum | thioredoxin reductase | 0.0802 | 0.289 | 0.5332 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0278 | 0.0989 | 0.0964 |
Schistosoma mansoni | glutamate synthase | 0.0074 | 0.0248 | 0.0248 |
Plasmodium falciparum | ADP-dependent DNA helicase RecQ | 0.0021 | 0.0058 | 0.0076 |
Trypanosoma brucei | heat shock protein 90, putative | 0.0055 | 0.018 | 0.0153 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0802 | 0.289 | 0.289 |
Treponema pallidum | oxidoreductase | 0.0074 | 0.0248 | 0.0839 |
Mycobacterium ulcerans | sensor kinase from two component regulatory system | 0.0055 | 0.018 | 0.1688 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0016 | 0.0039 | 0.0042 |
Echinococcus multilocularis | Pyruvate dehydrogenase (lipoamide) kinase | 0.099 | 0.3572 | 0.3572 |
Echinococcus granulosus | apoptosis inducing factor 1 mitochondrial | 0.0074 | 0.0248 | 0.0248 |
Echinococcus multilocularis | ATP dependent DNA helicase Q5 | 0.001 | 0.0017 | 0.0017 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0802 | 0.289 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0012 | 0.0022 | 0.0022 |
Leishmania major | NADH dehydrogenase, putative | 0.0074 | 0.0248 | 0.0221 |
Mycobacterium tuberculosis | Two component sensor histidine kinase DosT | 0.0055 | 0.018 | 0.0571 |
Echinococcus multilocularis | leucine rich repeat serine:threonine protein | 0.0062 | 0.0205 | 0.0205 |
Brugia malayi | Bloom's syndrome protein homolog | 0.0024 | 0.0069 | 0.0069 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0074 | 0.0248 | 0.0221 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.018 | 0.0153 |
Trypanosoma cruzi | Heat shock protein 83, putative | 0.0055 | 0.018 | 0.0153 |
Trypanosoma cruzi | DNA topoisomerase II, putative | 0.0055 | 0.018 | 0.0153 |
Trypanosoma brucei | heat shock protein, putative | 0.0055 | 0.018 | 0.0153 |
Loa Loa (eye worm) | hypothetical protein | 0.0362 | 0.1295 | 0.1295 |
Onchocerca volvulus | DNA topoisomerase 2 homolog | 0.0055 | 0.018 | 0.1035 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0075 | 0.0254 | 0.0254 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0041 | 0.0129 | 0.0102 |
Echinococcus granulosus | pyridine nucleotide disulfide oxidoreductase | 0.0074 | 0.0248 | 0.0248 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.0017 | 0.0017 |
Schistosoma mansoni | DNA helicase recq1 | 0.001 | 0.0017 | 0.0017 |
Mycobacterium tuberculosis | Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) | 0.0074 | 0.0248 | 0.0807 |
Trypanosoma cruzi | NADH dehydrogenase, putative | 0.0074 | 0.0248 | 0.0221 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.0017 | 0.0017 |
Loa Loa (eye worm) | hypothetical protein | 0.1495 | 0.5406 | 0.5406 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.018 | 0.0153 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0278 | 0.0989 | 1 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0012 | 0.0022 | 0.0022 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0022 | 0.0022 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.018 | 0.0153 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0022 | 0.0022 |
Schistosoma mansoni | hypothetical protein | 0.0387 | 0.1385 | 0.1385 |
Schistosoma mansoni | heat shock protein | 0.0055 | 0.018 | 0.018 |
Schistosoma mansoni | endoplasmin | 0.0055 | 0.018 | 0.018 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0278 | 0.0989 | 0.0989 |
Loa Loa (eye worm) | hypothetical protein | 0.0484 | 0.1737 | 0.1737 |
Loa Loa (eye worm) | hypothetical protein | 0.0342 | 0.122 | 0.122 |
Trichomonas vaginalis | sensory transduction histidine kinase bacterial, putative | 0.0055 | 0.018 | 0.1688 |
Loa Loa (eye worm) | hypothetical protein | 0.0006 | 0.0002 | 0.0002 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0278 | 0.0989 | 1 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0278 | 0.0989 | 1 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0074 | 0.0248 | 0.0807 |
Onchocerca volvulus | Putative DNA topoisomerase 2, mitochondrial | 0.0055 | 0.018 | 0.1035 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0012 | 0.0022 | 0.0022 |
Trypanosoma cruzi | mitochondrial DNA topoisomerase II, putative | 0.0055 | 0.018 | 0.0153 |
Trypanosoma cruzi | NADPH:adrenodoxin oxidoreductase, mitochondrial, putative | 0.0074 | 0.0248 | 0.0221 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0006 | 0.0002 | 0.0002 |
Plasmodium falciparum | NAD(P)H-dependent glutamate synthase, putative | 0.0074 | 0.0248 | 0.0429 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0012 | 0.0022 | 0.0022 |
Trichomonas vaginalis | receptor histidine kinase, putative | 0.0055 | 0.018 | 0.1688 |
Echinococcus multilocularis | dihydropyrimidine dehydrogenase (NADP+) | 0.0074 | 0.0248 | 0.0248 |
Trichomonas vaginalis | endoplasmin, putative | 0.0055 | 0.018 | 0.1688 |
Trypanosoma cruzi | mitochondrial DNA topoisomerase II, putative | 0.0055 | 0.018 | 0.0153 |
Giardia lamblia | Thioredoxin reductase | 0.0074 | 0.0248 | 0.2386 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0012 | 0.0022 | 0.0022 |
Plasmodium falciparum | glutathione reductase | 0.0278 | 0.0989 | 0.1803 |
Echinococcus multilocularis | pyridine nucleotide disulfide oxidoreductase | 0.0074 | 0.0248 | 0.0248 |
Mycobacterium tuberculosis | NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) | 0.0074 | 0.0248 | 0.0807 |
Mycobacterium ulcerans | two component system membrane associated sensor kinase | 0.0055 | 0.018 | 0.1688 |
Loa Loa (eye worm) | carbonic anhydrase 3 | 0.2761 | 1 | 1 |
Trypanosoma brucei | carbonic anhydrase-like protein | 0.2761 | 1 | 1 |
Onchocerca volvulus | GPI ethanolamine phosphate transferase 1 homolog | 0.001 | 0.0016 | 0.0091 |
Loa Loa (eye worm) | ATP-dependent DNA helicase | 0.001 | 0.0017 | 0.0017 |
Leishmania major | mitochondrial DNA topoisomerase II | 0.0055 | 0.018 | 0.0153 |
Entamoeba histolytica | pyridine nucleotide-disulfide oxidoreductase family protein | 0.0074 | 0.0248 | 0.1849 |
Trichomonas vaginalis | DNA helicase recq1, putative | 0.0024 | 0.0069 | 0.0543 |
Onchocerca volvulus | 0.0484 | 0.1737 | 0.9988 | |
Echinococcus granulosus | glutamate synthase | 0.0074 | 0.0248 | 0.0248 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0044 | 0.0139 | 0.0139 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0075 | 0.0254 | 0.0227 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0012 | 0.0022 | 0.0022 |
Onchocerca volvulus | 0.0484 | 0.1737 | 0.9988 | |
Plasmodium vivax | thioredoxin reductase, putative | 0.0802 | 0.289 | 1 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.1495 | 0.5406 | 0.5406 |
Toxoplasma gondii | heat shock protein HSP90 | 0.0055 | 0.018 | 0.0303 |
Brugia malayi | hypothetical protein | 0.0139 | 0.0485 | 0.0485 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0055 | 0.018 | 0.0153 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0012 | 0.0022 | 0.0022 |
Treponema pallidum | thioredoxin reductase (trxB) | 0.0074 | 0.0248 | 0.0839 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0278 | 0.0989 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0012 | 0.0022 | 0.0022 |
Mycobacterium tuberculosis | Conserved protein | 0.0041 | 0.0129 | 0.0395 |
Schistosoma mansoni | glutamate synthase | 0.0074 | 0.0248 | 0.0248 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0016 | 0.0016 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0802 | 0.289 | 0.289 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0129 | 0.0129 |
Brugia malayi | glutamate synthase | 0.0074 | 0.0248 | 0.0248 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0012 | 0.0022 | 0.0022 |
Onchocerca volvulus | 0.0041 | 0.0129 | 0.0744 | |
Trypanosoma brucei | pyridine nucleotide-disulphide oxidoreductase, putative | 0.0074 | 0.0248 | 0.0221 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0041 | 0.0129 | 0.0395 |
Brugia malayi | beta-lactamase | 0.0041 | 0.0129 | 0.0129 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.018 | 0.0153 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase family protein | 0.0074 | 0.0248 | 0.0248 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0055 | 0.018 | 0.0153 |
Echinococcus granulosus | ATP dependent DNA helicase Q5 | 0.001 | 0.0017 | 0.0017 |
Trypanosoma cruzi | pyridine nucleotide-disulphide oxidoreductase, putative | 0.0074 | 0.0248 | 0.0221 |
Brugia malayi | nuclear receptor RXR | 0.0006 | 0.0002 | 0.0002 |
Mycobacterium tuberculosis | Two component sensor kinase [second part] | 0.0055 | 0.018 | 0.0571 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0278 | 0.0989 | 0.0964 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0012 | 0.0022 | 0.0022 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0012 | 0.0022 | 0.0022 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0006 | 0.0002 | 0.0002 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0278 | 0.0989 | 0.0964 |
Mycobacterium ulcerans | NADPH:adrenodoxin oxidoreductase FprB | 0.0074 | 0.0248 | 0.2386 |
Mycobacterium tuberculosis | Probable two component sensor kinase | 0.0055 | 0.018 | 0.0571 |
Brugia malayi | hypothetical protein | 0.0006 | 0.0002 | 0.0002 |
Plasmodium falciparum | carbonic anhydrase | 0.1495 | 0.5406 | 1 |
Onchocerca volvulus | Peroxidasin homolog | 0.0485 | 0.1739 | 1 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0278 | 0.0989 | 0.0964 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0263 | 0.0934 | 0.3193 |
Schistosoma mansoni | carbonic anhydrase | 0.1495 | 0.5406 | 0.5406 |
Leishmania major | DNA topoisomerase ii | 0.0055 | 0.018 | 0.0153 |
Mycobacterium tuberculosis | Probable thioredoxin reductase TrxB2 (TRXR) (TR) | 0.0074 | 0.0248 | 0.0807 |
Brugia malayi | DNA gyrase/topoisomerase IV, A subunit family protein | 0.0055 | 0.018 | 0.018 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0041 | 0.0129 | 0.0129 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0278 | 0.0989 | 0.0964 |
Brugia malayi | Sulfatase family protein | 0.001 | 0.0016 | 0.0016 |
Plasmodium falciparum | type II NADH:ubiquinone oxidoreductase | 0.0074 | 0.0248 | 0.0429 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0342 | 0.122 | 1 |
Onchocerca volvulus | Chorion peroxidase homolog | 0.0484 | 0.1737 | 0.9988 |
Schistosoma mansoni | hypothetical protein | 0.0387 | 0.1385 | 0.1385 |
Loa Loa (eye worm) | hypothetical protein | 0.099 | 0.3572 | 0.3572 |
Mycobacterium tuberculosis | Possible two component system response sensor kinase membrane associated PhoR | 0.0055 | 0.018 | 0.0571 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0278 | 0.0989 | 1 |
Mycobacterium ulcerans | beta-lactamase | 0.0041 | 0.0129 | 0.1168 |
Entamoeba histolytica | glutamate synthase beta subunit, putative | 0.0074 | 0.0248 | 0.1849 |
Trypanosoma cruzi | pyridine nucleotide-disulphide oxidoreductase, putative | 0.0074 | 0.0248 | 0.0221 |
Loa Loa (eye worm) | glutathione reductase | 0.0802 | 0.289 | 0.289 |
Treponema pallidum | NADH oxidase | 0.0278 | 0.0989 | 1 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.2761 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0129 | 0.0129 |
Mycobacterium ulcerans | NADPH dependent 2,4-dienoyl-CoA reductase FadH | 0.0074 | 0.0248 | 0.2386 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0006 | 0.0002 | 0.0002 |
Trichomonas vaginalis | sensor histidine kinase, putative | 0.0055 | 0.018 | 0.1688 |
Trypanosoma brucei | NADH dehydrogenase | 0.0074 | 0.0248 | 0.0221 |
Schistosoma mansoni | endoplasmin | 0.0055 | 0.018 | 0.018 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0041 | 0.0129 | 0.0129 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0055 | 0.018 | 0.0153 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0802 | 0.289 | 0.289 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0074 | 0.0248 | 0.0221 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0012 | 0.0022 | 0.0022 |
Trichomonas vaginalis | DNA topoisomerase II, putative | 0.0055 | 0.018 | 0.1688 |
Mycobacterium ulcerans | putative regultory protein | 0.0055 | 0.018 | 0.1688 |
Brugia malayi | ecdysteroid receptor | 0.0012 | 0.0022 | 0.0022 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0012 | 0.0022 | 0.0022 |
Trypanosoma cruzi | DNA topoisomerase II, putative | 0.0055 | 0.018 | 0.0153 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0278 | 0.0989 | 0.3384 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0012 | 0.0022 | 0.0022 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0041 | 0.0129 | 0.0395 |
Brugia malayi | hypothetical protein | 0.001 | 0.0016 | 0.0016 |
Trypanosoma cruzi | NADH dehydrogenase, putative | 0.0074 | 0.0248 | 0.0221 |
Giardia lamblia | Pms1-like protein | 0.0055 | 0.018 | 0.1688 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.1495 | 0.5406 | 0.5406 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0278 | 0.0989 | 0.0964 |
Echinococcus multilocularis | apoptosis inducing factor 1 mitochondrial | 0.0074 | 0.0248 | 0.0248 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0041 | 0.0129 | 0.1168 |
Trichomonas vaginalis | heat shock protein, putative | 0.0055 | 0.018 | 0.1688 |
Toxoplasma gondii | ABC1 family protein | 0.0041 | 0.0129 | 0.0209 |
Loa Loa (eye worm) | heat shock protein 90 | 0.0055 | 0.018 | 0.018 |
Brugia malayi | follicle stimulating hormone receptor | 0.0265 | 0.094 | 0.094 |
Plasmodium vivax | hypothetical protein, conserved | 0.0055 | 0.018 | 0.0491 |
Plasmodium falciparum | thioredoxin reductase | 0.0278 | 0.0989 | 0.1803 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.018 | 0.0153 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0041 | 0.0129 | 0.0395 |
Trypanosoma cruzi | pyruvate dehydrogenase (lipoamide) kinase, putative | 0.0346 | 0.1236 | 0.1212 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0484 | 0.1737 | 0.1737 |
Loa Loa (eye worm) | hypothetical protein | 0.0484 | 0.1737 | 0.1737 |
Trichomonas vaginalis | sensory transduction histidine kinase, putative | 0.0055 | 0.018 | 0.1688 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase family protein | 0.0074 | 0.0248 | 0.0248 |
Echinococcus granulosus | ATP dependent DNA helicase Q1 | 0.001 | 0.0017 | 0.0017 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0278 | 0.0989 | 1 |
Mycobacterium tuberculosis | Conserved protein | 0.0041 | 0.0129 | 0.0395 |
Mycobacterium tuberculosis | Two component sensor histidine kinase PrrB | 0.0055 | 0.018 | 0.0571 |
Trichomonas vaginalis | mismatch repair protein Mlh1C (mutL homolog) | 0.0055 | 0.018 | 0.1688 |
Plasmodium vivax | DNA gyrase subunit B, putative | 0.0055 | 0.018 | 0.0491 |
Brugia malayi | steroid hormone receptor | 0.0012 | 0.0022 | 0.0022 |
Trichomonas vaginalis | two component sensor and regulator histidine kinase bacteria, putative | 0.0055 | 0.018 | 0.1688 |
Mycobacterium tuberculosis | Possible dehydrogenase/reductase | 0.0074 | 0.0248 | 0.0807 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0041 | 0.0129 | 0.0395 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0129 | 0.0129 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.0017 | 0.000000000030851 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0055 | 0.018 | 0.0153 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0055 | 0.018 | 0.0153 |
Echinococcus granulosus | dihydropyrimidine dehydrogenase NADP | 0.0074 | 0.0248 | 0.0248 |
Plasmodium vivax | endoplasmin, putative | 0.0055 | 0.018 | 0.0491 |
Mycobacterium tuberculosis | Possible two component sensor kinase | 0.0055 | 0.018 | 0.0571 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0278 | 0.0989 | 1 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0265 | 0.094 | 0.094 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0074 | 0.0248 | 0.2386 |
Plasmodium falciparum | DNA topoisomerase 2 | 0.0055 | 0.018 | 0.0303 |
Loa Loa (eye worm) | hypothetical protein | 0.0484 | 0.1737 | 0.1737 |
Leishmania major | pyruvate dehydrogenase (lipoamide) kinase, putative | 0.0346 | 0.1236 | 0.1212 |
Loa Loa (eye worm) | beta-lactamase | 0.0041 | 0.0129 | 0.0129 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0012 | 0.0022 | 0.0022 |
Toxoplasma gondii | ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein | 0.0055 | 0.018 | 0.0303 |
Trypanosoma brucei | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative | 0.0055 | 0.018 | 0.0153 |
Echinococcus multilocularis | NADPH:adrenodoxin oxidoreductase | 0.0074 | 0.0248 | 0.0248 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0278 | 0.0989 | 0.0964 |
Plasmodium falciparum | heat shock protein 90 | 0.0055 | 0.018 | 0.0303 |
Schistosoma mansoni | heat shock protein | 0.0055 | 0.018 | 0.018 |
Echinococcus granulosus | heat shock protein 90 | 0.0055 | 0.018 | 0.018 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0012 | 0.0022 | 0.0127 |
Echinococcus granulosus | protein cereblon | 0.0342 | 0.122 | 0.122 |
Loa Loa (eye worm) | hypothetical protein | 0.0484 | 0.1737 | 0.1737 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0012 | 0.0022 | 0.0022 |
Trichomonas vaginalis | receptor histidine kinase, putative | 0.0055 | 0.018 | 0.1688 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0012 | 0.0022 | 0.0022 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0012 | 0.0022 | 0.0022 |
Leishmania major | 2,4-dienoyl-coa reductase-like protein | 0.0074 | 0.0248 | 0.0221 |
Mycobacterium tuberculosis | Two component sensor histidine kinase DevS | 0.0055 | 0.018 | 0.0571 |
Trypanosoma cruzi | 2,4-dienoyl-coa reductase-like protein, putative | 0.0074 | 0.0248 | 0.0221 |
Trypanosoma brucei | heat shock protein, putative | 0.0055 | 0.018 | 0.0153 |
Mycobacterium tuberculosis | Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate | 0.0074 | 0.0248 | 0.0807 |
Mycobacterium leprae | Probable two-component sensor kinase | 0.0055 | 0.018 | 0.0588 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0802 | 0.289 | 0.2871 |
Trichomonas vaginalis | glutamate synthase, putative | 0.0074 | 0.0248 | 0.2386 |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.0484 | 0.1737 | 0.1737 |
Schistosoma mansoni | blooms syndrome DNA helicase | 0.0019 | 0.005 | 0.005 |
Brugia malayi | Animal haem peroxidase family protein | 0.0484 | 0.1737 | 0.1737 |
Echinococcus granulosus | carbonic anhydrase | 0.1495 | 0.5406 | 0.5406 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0012 | 0.0022 | 0.0022 |
Mycobacterium ulcerans | thioredoxin reductase TrxB2 | 0.0074 | 0.0248 | 0.2386 |
Echinococcus multilocularis | glutamate synthase | 0.0074 | 0.0248 | 0.0248 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.018 | 0.0153 |
Mycobacterium ulcerans | NADPH:adrenodoxin oxidoreductase FprA | 0.0074 | 0.0248 | 0.2386 |
Entamoeba histolytica | thioredoxin reductase, putative | 0.0074 | 0.0248 | 0.1849 |
Giardia lamblia | Glutamate synthase | 0.0074 | 0.0248 | 0.2386 |
Echinococcus multilocularis | carbonic anhydrase | 0.1495 | 0.5406 | 0.5406 |
Onchocerca volvulus | 0.0041 | 0.0129 | 0.0744 | |
Loa Loa (eye worm) | animal heme peroxidase | 0.0484 | 0.1737 | 0.1737 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0013 | 0.0027 | 0.012 |
Schistosoma mansoni | pyruvate dehydrogenase | 0.099 | 0.3572 | 0.3572 |
Trypanosoma brucei | Heat shock protein 83, putative | 0.0055 | 0.018 | 0.0153 |
Loa Loa (eye worm) | TKL/LRRK protein kinase | 0.0062 | 0.0205 | 0.0205 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0278 | 0.0989 | 0.1803 |
Leishmania major | trypanothione reductase | 0.0802 | 0.289 | 0.2871 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0012 | 0.0022 | 0.0022 |
Brugia malayi | kinase, mitochondrial precursor | 0.099 | 0.3572 | 0.3572 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0041 | 0.0129 | 0.0102 |
Leishmania major | carbonic anhydrase-like protein | 0.2761 | 1 | 1 |
Mycobacterium leprae | Probable two component sensor kinase MprB | 0.0055 | 0.018 | 0.0588 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0041 | 0.0129 | 0.0395 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0041 | 0.0129 | 0.0395 |
Leishmania major | hypothetical protein, conserved | 0.0074 | 0.0248 | 0.0221 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.1495 | 0.5406 | 0.5406 |
Schistosoma mansoni | carbonic anhydrase-related | 0.1495 | 0.5406 | 0.5406 |
Plasmodium vivax | hypothetical protein, conserved | 0.0041 | 0.0129 | 0.0314 |
Loa Loa (eye worm) | hypothetical protein | 0.0484 | 0.1737 | 0.1737 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0278 | 0.0989 | 0.0989 |
Mycobacterium tuberculosis | Two component sensory transduction histidine kinase MtrB | 0.0055 | 0.018 | 0.0571 |
Schistosoma mansoni | carbonic anhydrase-related | 0.1495 | 0.5406 | 0.5406 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (functional) | > 20 uM | Inhibition of LPS-induced nitric oxide production in human BV2 cells after 24 hrs by spectrophotometry | ChEMBL. | 23734721 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.