Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | PHD-finger family protein | 0.0033 | 0.0228 | 0.058 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0029 | 0.0184 | 0.0468 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0011 | 0.0016 | 0.0016 |
Echinococcus multilocularis | tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase | 0.0014 | 0.0042 | 0.0042 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0011 | 0.0016 | 0.0016 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.002 | 0.0106 | 0.5 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0054 | 0.0427 | 0.0427 |
Schistosoma mansoni | protein kinase | 0.001 | 0.001 | 0.001 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0016 | 0.0061 | 0.0156 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0045 | 0.0336 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0233 | 0.0233 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0016 | 0.0061 | 0.0261 |
Schistosoma mansoni | ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related | 0.0029 | 0.0184 | 0.0184 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0429 | 0.1093 |
Schistosoma mansoni | nuclear hormone receptor | 0.0011 | 0.0016 | 0.0016 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0107 | 0.0928 | 0.2361 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0045 | 0.0336 | 0.0772 |
Echinococcus granulosus | NCK adaptor protein | 0.0012 | 0.0026 | 0.0026 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0238 | 0.2174 | 0.5532 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0027 | 0.0173 | 0.0173 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0029 | 0.0184 | 0.0468 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0041 | 0.0301 | 0.0301 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0111 | 0.0969 | 0.2467 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0011 | 0.0016 | 0.0016 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0034 | 0.0233 | 0.0994 |
Toxoplasma gondii | exonuclease III APE | 0.002 | 0.0106 | 0.1784 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0045 | 0.0336 | 1 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0045 | 0.0336 | 0.1697 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0011 | 0.0016 | 0.0016 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0014 | 0.0042 | 0.0042 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0136 | 0.1206 | 0.3068 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0029 | 0.0184 | 0.5343 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0024 | 0.0138 | 0.0589 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0033 | 0.0228 | 0.0228 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0051 | 0.0399 | 0.0399 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.002 | 0.0106 | 0.0106 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.002 | 0.0106 | 0.0451 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0233 | 0.0233 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0427 | 0.1086 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0011 | 0.0016 | 0.0041 |
Schistosoma mansoni | phosphatidylserine receptor | 0.0029 | 0.0184 | 0.0184 |
Echinococcus granulosus | Jumonji AT rich interactive domain 1B | 0.0033 | 0.0221 | 0.0221 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0011 | 0.0016 | 0.0069 |
Echinococcus multilocularis | tyrosine protein kinase ABL1 | 0.0422 | 0.393 | 0.393 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0233 | 0.0233 |
Entamoeba histolytica | protein kinase, putative | 0.0015 | 0.0051 | 0.0041 |
Trypanosoma cruzi | ISWI complex protein | 0.0017 | 0.0078 | 0.2087 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0228 | 0.0228 |
Echinococcus granulosus | peregrin | 0.004 | 0.0292 | 0.0292 |
Brugia malayi | jmjC domain containing protein | 0.0029 | 0.0184 | 0.0783 |
Brugia malayi | Variant SH3 domain containing protein | 0.0012 | 0.0026 | 0.0109 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0033 | 0.0223 | 0.0223 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0233 | 0.0233 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0035 | 0.0242 | 0.0242 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0168 | 0.1508 | 0.6424 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0045 | 0.0336 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0011 | 0.0016 | 0.0041 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0041 | 0.0301 | 0.0301 |
Brugia malayi | nuclear hormone receptor | 0.0011 | 0.0016 | 0.0069 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0011 | 0.0016 | 0.0016 |
Echinococcus multilocularis | proto oncogene tyrosine protein kinase LCK | 0.0014 | 0.0042 | 0.0042 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.0208 | 0.0208 |
Schistosoma mansoni | protein kinase | 0.001 | 0.001 | 0.001 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0163 | 0.1459 | 1 |
Echinococcus multilocularis | lysine specific demethylase 6a | 0.0029 | 0.0184 | 0.0184 |
Plasmodium vivax | SET domain protein, putative | 0.0035 | 0.0242 | 0.5697 |
Schistosoma mansoni | tyrosine kinase | 0.0416 | 0.3872 | 0.3872 |
Echinococcus granulosus | jumonji domain containing 1A | 0.0029 | 0.0184 | 0.0184 |
Schistosoma mansoni | growth factor receptor-bound protein | 0.0012 | 0.0026 | 0.0026 |
Echinococcus multilocularis | growth factor receptor bound protein 2 | 0.0012 | 0.0026 | 0.0026 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0333 | 0.308 | 1 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0045 | 0.0335 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0016 | 0.0041 |
Trichomonas vaginalis | set domain proteins, putative | 0.0271 | 0.2486 | 0.8003 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0045 | 0.0336 | 1 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0011 | 0.0016 | 0.0016 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0176 | 0.1584 | 0.1584 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0328 | 0.0834 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.0678 | 0.1726 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0011 | 0.0016 | 0.0016 |
Trypanosoma brucei | PHD-zinc-finger like domain containing protein, putative | 0.0011 | 0.0015 | 0.0168 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0016 | 0.0061 | 0.0061 |
Echinococcus granulosus | JmjC domain containing protein 4 | 0.0029 | 0.0184 | 0.0184 |
Plasmodium vivax | JmjC domain containing protein | 0.0029 | 0.0184 | 0.4112 |
Loa Loa (eye worm) | TK/ABL protein kinase | 0.0422 | 0.393 | 1 |
Echinococcus granulosus | dual specificity testis-specific protein kinase | 0.001 | 0.001 | 0.001 |
Brugia malayi | Sex muscle abnormal protein 5 | 0.0012 | 0.0026 | 0.0109 |
Brugia malayi | nuclear receptor NHR-88 | 0.0011 | 0.0016 | 0.0069 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0045 | 0.0336 | 1 |
Brugia malayi | ecdysteroid receptor | 0.0011 | 0.0016 | 0.0069 |
Trypanosoma brucei | JmjC domain, hydroxylase, putative | 0.0029 | 0.0184 | 0.5343 |
Toxoplasma gondii | histone lysine demethylase JMJD6a | 0.0029 | 0.0184 | 0.3227 |
Brugia malayi | jmjC domain containing protein | 0.0029 | 0.0184 | 0.0783 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0027 | 0.0173 | 0.0173 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0014 | 0.0042 | 0.0042 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0107 | 0.0932 | 0.0932 |
Echinococcus multilocularis | NCK adaptor protein | 0.0012 | 0.0026 | 0.0026 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0016 | 0.0061 | 0.0052 |
Echinococcus multilocularis | jumonji domain containing 1A | 0.0029 | 0.0184 | 0.0184 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0016 | 0.0041 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0045 | 0.0336 | 1 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0074 | 0.0614 | 0.0614 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0011 | 0.0016 | 0.0041 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0011 | 0.0016 | 0.0041 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0045 | 0.0336 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0011 | 0.0016 | 0.0069 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0016 | 0.0061 | 0.0061 |
Brugia malayi | Bromodomain containing protein | 0.0091 | 0.078 | 0.3322 |
Schistosoma mansoni | protein phosphatase 2C | 0.0029 | 0.0184 | 0.0184 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0011 | 0.0016 | 0.0016 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0046 | 0.0352 | 0.0352 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0033 | 0.0228 | 0.0228 |
Trypanosoma brucei | unspecified product | 0.0037 | 0.0268 | 0.7911 |
Echinococcus granulosus | FTZ F1 alpha | 0.0011 | 0.0016 | 0.0016 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0014 | 0.0042 | 0.0042 |
Brugia malayi | CXXC zinc finger family protein | 0.0031 | 0.0208 | 0.0887 |
Toxoplasma gondii | BRCA1 C Terminus (BRCT) domain-containing protein | 0.0012 | 0.0026 | 0.0308 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0023 | 0.0129 | 0.0487 |
Echinococcus multilocularis | tyrosine protein kinase lyn tyrosine protein kinase blk | 0.0014 | 0.0042 | 0.0042 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.002 | 0.0106 | 0.0269 |
Echinococcus multilocularis | tyrosine protein kinase Src42A | 0.0014 | 0.0042 | 0.0042 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0011 | 0.0016 | 0.0016 |
Loa Loa (eye worm) | histone methyltransferase | 0.0011 | 0.0015 | 0.0039 |
Echinococcus granulosus | tyrosine protein kinase Src64B | 0.0014 | 0.0042 | 0.0042 |
Brugia malayi | Pre-SET motif family protein | 0.0035 | 0.0242 | 0.103 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0045 | 0.0336 | 1 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0014 | 0.0042 | 0.0042 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0011 | 0.0016 | 0.0016 |
Brugia malayi | jmjC domain containing protein | 0.0111 | 0.0969 | 0.4128 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.002 | 0.0106 | 0.1986 |
Brugia malayi | PHD-finger family protein | 0.0033 | 0.0228 | 0.097 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0228 | 0.058 |
Echinococcus multilocularis | phd:f box containing protein | 0.0029 | 0.0184 | 0.0184 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0011 | 0.0015 | 0.0015 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0333 | 0.308 | 1 |
Toxoplasma gondii | histone lysine demethylase JMJC1/KDM5D/JARID1D | 0.0029 | 0.0184 | 0.3227 |
Giardia lamblia | DINP protein human, muc B family | 0.0023 | 0.0129 | 0.0079 |
Echinococcus multilocularis | JmjC domain containing protein 4 | 0.0029 | 0.0184 | 0.0184 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0111 | 0.0969 | 0.0969 |
Echinococcus multilocularis | dual specificity testis specific protein kinase | 0.001 | 0.001 | 0.001 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0233 | 0.0592 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0011 | 0.0015 | 0.0101 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0014 | 0.0042 | 0.0042 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0333 | 0.308 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0011 | 0.0015 | 0.0015 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0333 | 0.308 | 1 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0034 | 0.0233 | 0.0233 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0027 | 0.0173 | 0.0173 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0019 | 0.0097 | 0.0097 |
Echinococcus granulosus | tyrosine protein kinase ABL1 | 0.0422 | 0.393 | 0.393 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0136 | 0.1206 | 0.3068 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0011 | 0.0016 | 0.0069 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0333 | 0.308 | 1 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0069 | 0.0564 | 0.1436 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.002 | 0.0106 | 0.2953 |
Schistosoma mansoni | tyrosine kinase | 0.0014 | 0.0042 | 0.0042 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.002 | 0.0106 | 0.0106 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0014 | 0.0042 | 0.0042 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0333 | 0.308 | 1 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0011 | 0.0016 | 0.0016 |
Leishmania major | DNA polymerase eta, putative | 0.0016 | 0.0061 | 0.296 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0033 | 0.0228 | 0.4043 |
Echinococcus multilocularis | calcium:calmodulin dependent protein kinase I | 0.106 | 0.9996 | 0.9996 |
Giardia lamblia | PHD finger protein 15 | 0.0033 | 0.0228 | 0.041 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0011 | 0.0016 | 0.0069 |
Schistosoma mansoni | tyrosine kinase | 0.0014 | 0.0042 | 0.0042 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0184 | 0.0468 |
Schistosoma mansoni | tyrosine kinase | 0.0014 | 0.0042 | 0.0042 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0034 | 0.0233 | 0.0233 |
Echinococcus multilocularis | cpg binding protein | 0.0035 | 0.0246 | 0.0246 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0011 | 0.0016 | 0.0069 |
Leishmania major | DNA polymerase kappa, putative | 0.0023 | 0.0129 | 0.6869 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0011 | 0.0016 | 0.0016 |
Schistosoma mansoni | hypothetical protein | 0.0073 | 0.0606 | 0.0606 |
Schistosoma mansoni | zinc finger protein | 0.0028 | 0.0179 | 0.0179 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.002 | 0.0106 | 0.032 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0011 | 0.0016 | 0.0041 |
Echinococcus multilocularis | GPCR, family 2 | 0.0034 | 0.0233 | 0.0233 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0011 | 0.0016 | 0.0041 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0067 | 0.0552 | 0.0552 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0051 | 0.0399 | 0.0987 |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.0019 | 0.0097 | 0.0097 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0018 | 0.0083 | 0.2248 |
Echinococcus granulosus | cpg binding protein | 0.0035 | 0.0246 | 0.0246 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0033 | 0.0228 | 0.0228 |
Echinococcus granulosus | 3'partial|tyrosine protein kinase Fgr | 0.0014 | 0.0042 | 0.0042 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0035 | 0.0242 | 0.0242 |
Echinococcus multilocularis | peregrin | 0.004 | 0.0292 | 0.0292 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0392 | 0.0997 |
Brugia malayi | Bromodomain containing protein | 0.004 | 0.0292 | 0.1243 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.002 | 0.0106 | 0.5527 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0014 | 0.0035 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0054 | 0.0427 | 0.0427 |
Loa Loa (eye worm) | variant SH3 domain-containing protein | 0.0012 | 0.0026 | 0.0065 |
Leishmania major | hypothetical protein, conserved | 0.0029 | 0.0184 | 1 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0011 | 0.0016 | 0.0016 |
Schistosoma mansoni | proto-oncogene tyrosine-protein kinase abl1 | 0.0012 | 0.0026 | 0.0026 |
Loa Loa (eye worm) | hypothetical protein | 0.016 | 0.1436 | 0.3654 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0011 | 0.0016 | 0.0016 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0168 | 0.1508 | 0.1508 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0045 | 0.0336 | 1 |
Trypanosoma brucei | unspecified product | 0.0011 | 0.0015 | 0.016 |
Schistosoma mansoni | bromodomain containing protein | 0.0011 | 0.0014 | 0.0014 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0016 | 0.0061 | 0.1582 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0011 | 0.0016 | 0.0069 |
Brugia malayi | jmjC domain containing protein | 0.0029 | 0.0184 | 0.0783 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0034 | 0.0233 | 0.684 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0067 | 0.0549 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0035 | 0.0242 | 0.0242 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0011 | 0.0016 | 0.0016 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0034 | 0.0233 | 0.0994 |
Schistosoma mansoni | protein kinase | 0.001 | 0.001 | 0.001 |
Schistosoma mansoni | jumonji domain containing protein | 0.0029 | 0.0184 | 0.0184 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0016 | 0.0041 |
Echinococcus granulosus | proto oncogene tyrosine protein kinase LCK | 0.0014 | 0.0042 | 0.0042 |
Brugia malayi | AF-10 protein | 0.0011 | 0.0015 | 0.0064 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0233 | 0.0594 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0333 | 0.308 | 1 |
Echinococcus multilocularis | activin receptor type | 0.001 | 0.001 | 0.001 |
Schistosoma mansoni | ap endonuclease | 0.002 | 0.0106 | 0.0106 |
Brugia malayi | jmjC domain containing protein | 0.0029 | 0.0184 | 0.0783 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0111 | 0.0969 | 0.0969 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.002 | 0.0106 | 0.0096 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0333 | 0.308 | 0.3073 |
Echinococcus granulosus | zinc finger protein | 0.0028 | 0.0179 | 0.0179 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0011 | 0.0016 | 0.0069 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0023 | 0.0129 | 0.6869 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0444 | 0.4133 | 0.4133 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0054 | 0.0427 | 0.0427 |
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.0928 | 0.2361 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0011 | 0.0016 | 0.0016 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0018 | 0.0083 | 0.2248 |
Trypanosoma brucei | ISWI complex protein | 0.0017 | 0.0078 | 0.2087 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0176 | 0.1584 | 0.1584 |
Onchocerca volvulus | 0.0014 | 0.005 | 0.0136 | |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0034 | 0.0233 | 0.684 |
Echinococcus granulosus | dna polymerase kappa | 0.0045 | 0.0336 | 0.0336 |
Schistosoma mansoni | tyrosine kinase | 0.0014 | 0.0042 | 0.0042 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0011 | 0.0016 | 0.0069 |
Entamoeba histolytica | SH2-protein kinase domain containing protein | 0.0015 | 0.0051 | 0.0041 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.0163 | 0.1459 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0011 | 0.0016 | 0.0069 |
Schistosoma mansoni | nck2/grb4 | 0.0012 | 0.0026 | 0.0026 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0045 | 0.0336 | 1 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0051 | 0.0399 | 0.7223 |
Echinococcus multilocularis | dna polymerase kappa | 0.0045 | 0.0336 | 0.0336 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0011 | 0.0016 | 0.0069 |
Plasmodium falciparum | phd finger protein, putative | 0.0033 | 0.0228 | 0.6699 |
Trypanosoma brucei | unspecified product | 0.0011 | 0.0015 | 0.016 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0011 | 0.0016 | 0.0069 |
Loa Loa (eye worm) | sex muscle abnormal protein 5 | 0.0012 | 0.0026 | 0.0065 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0045 | 0.0336 | 1 |
Trypanosoma brucei | PHD-zinc-finger like domain containing protein, putative | 0.0011 | 0.0015 | 0.0168 |
Schistosoma mansoni | cpg binding protein | 0.0035 | 0.0246 | 0.0246 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0011 | 0.0016 | 0.0041 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0016 | 0.0041 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0029 | 0.0184 | 0.5343 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0011 | 0.0016 | 0.0069 |
Echinococcus granulosus | jumonji domain containing protein | 0.0046 | 0.0352 | 0.0352 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0111 | 0.0969 | 0.0969 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0023 | 0.0129 | 0.367 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0051 | 0.0399 | 1 |
Onchocerca volvulus | 0.0271 | 0.2486 | 1 | |
Echinococcus multilocularis | Jumonji, AT rich interactive domain 1B | 0.0033 | 0.0221 | 0.0221 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0034 | 0.0233 | 0.0233 |
Brugia malayi | Bromodomain containing protein | 0.0048 | 0.0365 | 0.1556 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0011 | 0.0016 | 0.0069 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.0045 | 0.0335 | 0.0771 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0016 | 0.0041 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0019 | 0.0097 | 0.0097 |
Onchocerca volvulus | 0.0035 | 0.0242 | 0.0914 | |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0011 | 0.0016 | 0.0016 |
Schistosoma mansoni | hypothetical protein | 0.0024 | 0.0135 | 0.0135 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0011 | 0.0016 | 0.0016 |
Toxoplasma gondii | WD domain, G-beta repeat-containing protein | 0.0011 | 0.0015 | 0.0101 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0051 | 0.0399 | 0.7223 |
Brugia malayi | Variant SH3 domain containing protein | 0.0012 | 0.0026 | 0.0109 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0045 | 0.0336 | 0.0772 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0061 | 0.0156 |
Echinococcus granulosus | activin receptor type | 0.001 | 0.001 | 0.001 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0045 | 0.0336 | 0.1697 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0053 | 0.0134 |
Trypanosoma cruzi | ISWI complex protein | 0.0017 | 0.0078 | 0.2087 |
Plasmodium falciparum | JmjC domain-containing protein, putative | 0.0029 | 0.0184 | 0.5348 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0011 | 0.0016 | 0.0016 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0034 | 0.0233 | 0.0233 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0024 | 0.0135 | 0.0345 |
Brugia malayi | PHD-finger family protein | 0.0034 | 0.0237 | 0.101 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0016 | 0.0041 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0026 | 0.0065 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0054 | 0.0427 | 0.0427 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.002 | 0.0106 | 0.2956 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0011 | 0.0016 | 0.0069 |
Schistosoma mansoni | coup transcription factor | 0.0011 | 0.0016 | 0.0016 |
Entamoeba histolytica | protein kinase, putative | 0.106 | 1 | 1 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0168 | 0.1508 | 0.1508 |
Schistosoma mansoni | jumonji domain containing protein | 0.0153 | 0.1371 | 0.1371 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0045 | 0.0336 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.106 | 1 | 1 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0011 | 0.0016 | 0.0016 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0333 | 0.308 | 0.3073 |
Echinococcus multilocularis | tyrosine protein kinase Abl | 0.0172 | 0.155 | 0.155 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.016 | 0.1439 | 0.1439 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0011 | 0.0016 | 0.0016 |
Plasmodium vivax | hypothetical protein, conserved | 0.0033 | 0.0228 | 0.5314 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0011 | 0.0016 | 0.0041 |
Brugia malayi | jmjC domain containing protein | 0.0176 | 0.1584 | 0.6747 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0024 | 0.0142 | 0.0361 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0011 | 0.0016 | 0.0069 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0011 | 0.0015 | 0.0015 |
Loa Loa (eye worm) | SRC-1 | 0.0014 | 0.0042 | 0.0106 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0016 | 0.0061 | 0.0061 |
Schistosoma mansoni | hypothetical protein | 0.0444 | 0.4133 | 0.4133 |
Echinococcus multilocularis | serine:threonine protein kinase Chk2 | 0.106 | 1 | 1 |
Echinococcus granulosus | calcium:calmodulin dependent protein kinase I | 0.106 | 0.9996 | 0.9996 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0624 | 0.1587 |
Echinococcus multilocularis | tyrosine protein kinase Btk29A | 0.0014 | 0.0042 | 0.0042 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0333 | 0.308 | 1 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0031 | 0.0208 | 0.053 |
Schistosoma mansoni | adapter molecule crk | 0.0012 | 0.0026 | 0.0026 |
Plasmodium falciparum | conserved Plasmodium membrane protein, unknown function | 0.0013 | 0.0033 | 0.0723 |
Brugia malayi | polk-prov protein | 0.0034 | 0.0233 | 0.0991 |
Leishmania major | hypothetical protein, conserved | 0.0017 | 0.0078 | 0.3905 |
Echinococcus granulosus | dna polymerase eta | 0.0016 | 0.0061 | 0.0061 |
Echinococcus granulosus | dnaJ subfamily B | 0.0444 | 0.4133 | 0.4133 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0045 | 0.0336 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0016 | 0.0041 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0016 | 0.0061 | 0.1582 |
Echinococcus granulosus | lysine specific demethylase 6a | 0.0029 | 0.0184 | 0.0184 |
Echinococcus multilocularis | zinc finger protein | 0.0028 | 0.0179 | 0.0179 |
Schistosoma mansoni | DNA polymerase eta | 0.0016 | 0.0061 | 0.0061 |
Brugia malayi | steroid hormone receptor | 0.0011 | 0.0016 | 0.0069 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.0019 | 0.0097 | 0.0097 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0011 | 0.0016 | 0.0016 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0029 | 0.0184 | 0.0468 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0037 | 0.0268 | 0.7911 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0035 | 0.0242 | 0.4303 |
Echinococcus granulosus | tyrosine protein kinase Src42A | 0.0014 | 0.0042 | 0.0042 |
Schistosoma mansoni | growth factor receptor-bound protein | 0.0012 | 0.0026 | 0.0026 |
Schistosoma mansoni | thyroid hormone receptor | 0.0011 | 0.0016 | 0.0016 |
Schistosoma mansoni | ap endonuclease | 0.002 | 0.0106 | 0.0106 |
Schistosoma mansoni | proto-oncogene tyrosine-protein kinase src | 0.0014 | 0.0042 | 0.0042 |
Echinococcus granulosus | tyrosine protein kinase Btk29A | 0.0014 | 0.0042 | 0.0042 |
Echinococcus multilocularis | c src tyrosine kinase | 0.0014 | 0.0042 | 0.0042 |
Echinococcus multilocularis | dna polymerase eta | 0.0016 | 0.0061 | 0.0061 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0051 | 0.0399 | 0.0987 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0033 | 0.0228 | 0.4043 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0045 | 0.0336 | 1 |
Onchocerca volvulus | 0.0031 | 0.0208 | 0.0778 | |
Schistosoma mansoni | zinc finger protein | 0.0017 | 0.0078 | 0.0078 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0011 | 0.0016 | 0.0016 |
Brugia malayi | PHD-finger family protein | 0.0015 | 0.0053 | 0.0225 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0016 | 0.0041 |
Brugia malayi | Tyrosine-protein kinase abl-1 | 0.0256 | 0.2348 | 1 |
Schistosoma mansoni | phd/f-box containing protein | 0.0029 | 0.0184 | 0.0184 |
Brugia malayi | MH2 domain containing protein | 0.0136 | 0.1206 | 0.5135 |
Echinococcus multilocularis | tyrosine protein kinase Fgr | 0.0014 | 0.0042 | 0.0042 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.002 | 0.0101 | 0.0101 |
Onchocerca volvulus | Alhambra homolog | 0.0033 | 0.0228 | 0.0857 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0333 | 0.308 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0606 | 0.1543 |
Loa Loa (eye worm) | acetyltransferase | 0.0168 | 0.1508 | 0.3838 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0073 | 0.0606 | 0.2583 |
Echinococcus granulosus | growth factor receptor bound protein 2 | 0.0012 | 0.0026 | 0.0026 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0163 | 0.1459 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0333 | 0.308 | 1 |
Echinococcus granulosus | GPCR family 2 | 0.0034 | 0.0233 | 0.0233 |
Echinococcus granulosus | tyrosine protein kinase Lyn | 0.0022 | 0.0123 | 0.0123 |
Echinococcus multilocularis | tyrosine protein kinase Src64B | 0.0014 | 0.0042 | 0.0042 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0107 | 0.0928 | 0.3952 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0078 | 0.0078 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0034 | 0.0233 | 0.0594 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0011 | 0.0016 | 0.0016 |
Brugia malayi | SRC-1 | 0.0014 | 0.0042 | 0.0178 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0018 | 0.0083 | 0.2248 |
Schistosoma mansoni | serine/threonine protein kinase | 0.106 | 1 | 1 |
Schistosoma mansoni | bromodomain containing protein | 0.0078 | 0.0653 | 0.0653 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0074 | 0.0614 | 0.0614 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0107 | 0.0928 | 0.3952 |
Schistosoma mansoni | cpg binding protein | 0.0035 | 0.0246 | 0.0246 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0016 | 0.0061 | 0.0261 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.002 | 0.0106 | 0.2953 |
Brugia malayi | Tyrosine-protein kinase abl-1 | 0.0172 | 0.155 | 0.6601 |
Schistosoma mansoni | thyroid hormone receptor | 0.0011 | 0.0016 | 0.0016 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0016 | 0.0061 | 0.0061 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0045 | 0.0335 | 0.0326 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0011 | 0.0016 | 0.0069 |
Echinococcus granulosus | c src tyrosine kinase | 0.0014 | 0.0042 | 0.0042 |
Brugia malayi | Pre-SET motif family protein | 0.0238 | 0.2174 | 0.9259 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0184 | 0.0468 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0011 | 0.0016 | 0.0016 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.002 | 0.0106 | 0.2953 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0045 | 0.0336 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0011 | 0.0016 | 0.0016 |
Echinococcus granulosus | phd:f box containing protein | 0.0029 | 0.0184 | 0.0184 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
GI50 (functional) | = 14.05 uM | Growth inhibition of human NCI-H460 cells after 48 hrs by SRB assay | ChEMBL. | 24411197 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.