Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | lamin | 0.0055 | 0.0432 | 0.0746 |
Loa Loa (eye worm) | carboxylesterase | 0.0066 | 0.0607 | 0.0607 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0075 | 0.0761 | 0.0344 |
Brugia malayi | Animal haem peroxidase family protein | 0.0051 | 0.0359 | 0.0359 |
Onchocerca volvulus | 0.0194 | 0.2748 | 0.7874 | |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.0875 | 0.0875 |
Brugia malayi | beta-lactamase family protein | 0.0075 | 0.0761 | 0.0761 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0277 | 0.4149 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0428 | 0.6677 | 0.6677 |
Echinococcus granulosus | jun protein | 0.0246 | 0.3635 | 0.9918 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0761 | 0.0761 |
Trypanosoma cruzi | mitogen-activated protein kinase 3, putative | 0.0122 | 0.1555 | 0.4951 |
Brugia malayi | Furin-like cysteine rich region family protein | 0.0145 | 0.1933 | 0.1933 |
Brugia malayi | nuclear receptor NHR-88 | 0.0072 | 0.0707 | 0.0707 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0168 | 0.2314 | 0.5388 |
Brugia malayi | nuclear receptor RXR | 0.0072 | 0.0707 | 0.0707 |
Echinococcus granulosus | carbonic anhydrase | 0.0082 | 0.0875 | 0.2015 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0072 | 0.0707 | 0.0707 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0248 | 0.3664 | 1 |
Schistosoma mansoni | chondroitin sulfate proteoglycan-related | 0.0047 | 0.0294 | 0.0285 |
Brugia malayi | hypothetical protein | 0.0194 | 0.2748 | 0.2748 |
Echinococcus multilocularis | acetylcholinesterase | 0.0066 | 0.0607 | 0.1096 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0707 | 0.0707 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0082 | 0.0875 | 0.0875 |
Schistosoma mansoni | coup transcription factor | 0.0152 | 0.2057 | 0.4386 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0171 | 0.0171 |
Trypanosoma brucei | carbonic anhydrase-like protein | 0.0174 | 0.2425 | 1 |
Schistosoma mansoni | peroxidasin | 0.0051 | 0.0359 | 0.0437 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0152 | 0.2057 | 0.2057 |
Echinococcus granulosus | Polycystic kidney disease protein | 0.0062 | 0.054 | 0.1057 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0072 | 0.0702 | 0.0702 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0152 | 0.2057 | 0.2057 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0415 | 0.0415 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.004 | 0.0179 | 0.0017 |
Loa Loa (eye worm) | hypothetical protein | 0.024 | 0.3522 | 0.3522 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0075 | 0.0761 | 0.1689 |
Brugia malayi | hypothetical protein | 0.0072 | 0.0707 | 0.0707 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0152 | 0.2057 | 0.5399 |
Echinococcus granulosus | peroxidasin | 0.0051 | 0.0359 | 0.0538 |
Echinococcus granulosus | pikachurin | 0.0047 | 0.0294 | 0.0351 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.0174 | 0.2425 | 1 |
Loa Loa (eye worm) | beta-lactamase | 0.0075 | 0.0761 | 0.0761 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.0875 | 0.0875 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0055 | 0.0432 | 0.0432 |
Echinococcus multilocularis | slit 2 protein | 0.0064 | 0.057 | 0.1004 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0082 | 0.0875 | 0.1637 |
Schistosoma mansoni | zinc finger protein | 0.0072 | 0.0707 | 0.1247 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0072 | 0.0707 | 0.1535 |
Schistosoma mansoni | lamin | 0.0055 | 0.0432 | 0.0606 |
Onchocerca volvulus | 0.0072 | 0.0707 | 0.1638 | |
Loa Loa (eye worm) | solute carrier family 6 member 4 | 0.0235 | 0.3443 | 0.3443 |
Schistosoma mansoni | tyrosine kinase | 0.0077 | 0.0794 | 0.145 |
Onchocerca volvulus | 0.0051 | 0.0359 | 0.0574 | |
Echinococcus granulosus | melanoma receptor tyrosine protein kinase | 0.0078 | 0.0808 | 0.1824 |
Onchocerca volvulus | 0.0062 | 0.054 | 0.1128 | |
Schistosoma mansoni | hypothetical protein | 0.0074 | 0.0742 | 0.1329 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.008 | 0.0852 | 0.1583 |
Schistosoma mansoni | jun-related protein | 0.02 | 0.2861 | 0.6256 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0082 | 0.0875 | 0.0875 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0072 | 0.0707 | 0.1247 |
Brugia malayi | hypothetical protein | 0.0062 | 0.054 | 0.054 |
Loa Loa (eye worm) | doublecortin family protein | 0.0062 | 0.054 | 0.054 |
Brugia malayi | Protein kinase domain containing protein | 0.0046 | 0.0279 | 0.0279 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0152 | 0.2057 | 0.2057 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0051 | 0.0359 | 0.0359 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0074 | 0.0742 | 0.1329 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.0174 | 0.2425 | 0.2425 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0152 | 0.2057 | 0.2057 |
Onchocerca volvulus | Peroxidasin homolog | 0.0051 | 0.0359 | 0.0574 |
Onchocerca volvulus | 0.0055 | 0.0432 | 0.0797 | |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0072 | 0.0702 | 0.1234 |
Onchocerca volvulus | 0.0235 | 0.3443 | 1 | |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0152 | 0.2057 | 0.4741 |
Echinococcus granulosus | slit 2 protein | 0.0064 | 0.057 | 0.1144 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0707 | 0.0707 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0152 | 0.2057 | 0.2057 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0072 | 0.0707 | 0.1348 |
Echinococcus granulosus | intermediate filament protein | 0.0055 | 0.0432 | 0.0746 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0152 | 0.2057 | 0.2057 |
Brugia malayi | hypothetical protein | 0.0062 | 0.054 | 0.054 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0152 | 0.2057 | 0.5399 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0066 | 0.0607 | 0.1014 |
Onchocerca volvulus | 0.0055 | 0.0432 | 0.0797 | |
Schistosoma mansoni | hypothetical protein | 0.0056 | 0.0442 | 0.063 |
Onchocerca volvulus | 0.0075 | 0.0761 | 0.1803 | |
Brugia malayi | P38 map kinase family protein 2 | 0.0122 | 0.1555 | 0.1555 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0152 | 0.2057 | 0.5763 |
Plasmodium vivax | multidomain scavenger receptor, putative | 0.0062 | 0.054 | 0.6255 |
Brugia malayi | Animal haem peroxidase family protein | 0.0051 | 0.0359 | 0.0359 |
Brugia malayi | tailless protein | 0.0072 | 0.0707 | 0.0707 |
Onchocerca volvulus | 0.0051 | 0.0359 | 0.0574 | |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0761 | 0.0761 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0152 | 0.2057 | 0.2057 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0707 | 0.0707 |
Schistosoma mansoni | lipoxygenase | 0.013 | 0.168 | 0.351 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0359 | 0.0359 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0125 | 0.1594 | 0.3577 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0072 | 0.0707 | 0.0707 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0055 | 0.0432 | 0.0432 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0241 | 0.3549 | 0.8492 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0359 | 0.0359 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0359 | 0.0359 |
Echinococcus multilocularis | lamin | 0.0055 | 0.0432 | 0.0655 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0075 | 0.0761 | 0.0344 |
Schistosoma mansoni | laminin gamma-3 chain | 0.0064 | 0.057 | 0.0929 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0074 | 0.0742 | 0.1636 |
Schistosoma mansoni | hypothetical protein | 0.0062 | 0.054 | 0.0858 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0072 | 0.0707 | 0.1535 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0072 | 0.0707 | 0.1535 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.0875 | 0.0875 |
Brugia malayi | laminin alpha chain | 0.0047 | 0.0294 | 0.0294 |
Loa Loa (eye worm) | abnormal epIthelia family member | 0.0047 | 0.0294 | 0.0294 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0041 | 0.0196 | 0.0064 |
Schistosoma mansoni | hypothetical protein | 0.0125 | 0.1594 | 0.331 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0075 | 0.0761 | 0.1372 |
Schistosoma mansoni | thyroid hormone receptor | 0.0277 | 0.4149 | 0.9252 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0066 | 0.0607 | 0.1096 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0152 | 0.2057 | 0.2057 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0241 | 0.3549 | 0.9671 |
Brugia malayi | nuclear hormone receptor | 0.0152 | 0.2057 | 0.2057 |
Brugia malayi | Carboxylesterase family protein | 0.0066 | 0.0607 | 0.0607 |
Echinococcus multilocularis | insulin receptor | 0.0046 | 0.0279 | 0.0271 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0607 | 0.0607 |
Loa Loa (eye worm) | serotonin transporter b | 0.0235 | 0.3443 | 0.3443 |
Onchocerca volvulus | 0.0062 | 0.054 | 0.1128 | |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0152 | 0.2057 | 0.2057 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0171 | 0.0171 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0171 | 0.0171 |
Brugia malayi | hypothetical protein | 0.0051 | 0.0359 | 0.0359 |
Onchocerca volvulus | Chorion peroxidase homolog | 0.0051 | 0.0359 | 0.0574 |
Brugia malayi | laminin-like protein K08C7.3 precursor | 0.0047 | 0.0294 | 0.0294 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0152 | 0.2057 | 0.2057 |
Toxoplasma gondii | ABC1 family protein | 0.0075 | 0.0761 | 0.8382 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.048 | 0.7546 | 1 |
Leishmania major | carbonic anhydrase-like protein | 0.0174 | 0.2425 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0761 | 0.0761 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0359 | 0.0359 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0152 | 0.2057 | 0.5399 |
Brugia malayi | Putative carbonic anhydrase 5 precursor | 0.0174 | 0.2425 | 0.2425 |
Echinococcus multilocularis | pikachurin | 0.0047 | 0.0294 | 0.0308 |
Loa Loa (eye worm) | CMGC/MAPK/P38 protein kinase | 0.0122 | 0.1555 | 0.1555 |
Mycobacterium leprae | Probable lipase LipE | 0.0075 | 0.0761 | 0.5 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0078 | 0.0808 | 0.1824 |
Echinococcus granulosus | acetylcholinesterase | 0.0066 | 0.0607 | 0.1248 |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 0.2057 | 0.2057 |
Echinococcus granulosus | lamin dm0 | 0.0055 | 0.0432 | 0.0746 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0072 | 0.0707 | 0.0707 |
Brugia malayi | Animal haem peroxidase family protein | 0.0051 | 0.0359 | 0.0359 |
Brugia malayi | bZIP transcription factor family protein | 0.0246 | 0.3635 | 0.3635 |
Echinococcus granulosus | mitogen activated protein kinase 14 | 0.0122 | 0.1555 | 0.3962 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0152 | 0.2057 | 0.4741 |
Brugia malayi | beta-lactamase family protein | 0.0075 | 0.0761 | 0.0761 |
Loa Loa (eye worm) | hypothetical protein | 0.0062 | 0.054 | 0.054 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0152 | 0.2057 | 0.5399 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0152 | 0.2057 | 0.4741 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0359 | 0.0359 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0761 | 0.0761 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0707 | 0.0707 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0171 | 0.0171 |
Onchocerca volvulus | Peroxidase homolog | 0.0051 | 0.0359 | 0.0574 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0152 | 0.2057 | 0.5399 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0152 | 0.2057 | 0.2057 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0171 | 0.0171 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0072 | 0.0707 | 0.0707 |
Loa Loa (eye worm) | Sodium:neurotransmitter symporter family protein | 0.004 | 0.0171 | 0.0171 |
Echinococcus granulosus | nuclear factor of activated T cells 5 | 0.0145 | 0.1926 | 0.5025 |
Schistosoma mansoni | nuclear hormone receptor | 0.0072 | 0.0707 | 0.1247 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0152 | 0.2057 | 0.2057 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.0174 | 0.2425 | 1 |
Chlamydia trachomatis | Ssodium-dependent amino acid transporter | 0.004 | 0.0171 | 0.5 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.008 | 0.0852 | 0.1949 |
Echinococcus multilocularis | carbonic anhydrase II | 0.0174 | 0.2425 | 0.5666 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0707 | 0.0707 |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.0051 | 0.0359 | 0.0359 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.0742 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0152 | 0.2057 | 0.4386 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0152 | 0.2057 | 0.4741 |
Onchocerca volvulus | Dual oxidase homolog | 0.0051 | 0.0359 | 0.0574 |
Onchocerca volvulus | 0.0051 | 0.0359 | 0.0574 | |
Schistosoma mansoni | hypothetical protein | 0.0184 | 0.2582 | 0.5607 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0152 | 0.2057 | 0.4386 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0074 | 0.0742 | 0.1436 |
Echinococcus granulosus | geminin | 0.0184 | 0.2582 | 0.6902 |
Trichomonas vaginalis | glutaminase, putative | 0.0296 | 0.447 | 1 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0072 | 0.0707 | 0.1638 |
Echinococcus multilocularis | insulin growth factor 1 receptor beta | 0.0046 | 0.0279 | 0.0271 |
Schistosoma mansoni | nuclear receptor | 0.0072 | 0.0707 | 0.1247 |
Mycobacterium leprae | conserved hypothetical protein | 0.0075 | 0.0761 | 0.5 |
Schistosoma mansoni | polycystin 1-related | 0.0062 | 0.054 | 0.0858 |
Loa Loa (eye worm) | glutaminase | 0.0296 | 0.447 | 0.447 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0432 | 0.0432 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0152 | 0.2057 | 0.2057 |
Echinococcus granulosus | RUN | 0.0062 | 0.054 | 0.1057 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.0082 | 0.0875 | 0.0875 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.0082 | 0.0875 | 0.0875 |
Schistosoma mansoni | tyrosine kinase | 0.0078 | 0.0808 | 0.1482 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0707 | 0.0707 |
Echinococcus granulosus | mitogen activated protein kinase 11 | 0.0122 | 0.1555 | 0.3962 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0171 | 0.0171 |
Brugia malayi | hypothetical protein | 0.008 | 0.0852 | 0.0852 |
Brugia malayi | EGF-like domain containing protein | 0.0064 | 0.057 | 0.057 |
Brugia malayi | nuclear hormone receptor | 0.0072 | 0.0707 | 0.0707 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0061 | 0.0517 | 0.0517 |
Schistosoma mansoni | nuclear hormone receptor | 0.0152 | 0.2057 | 0.4386 |
Echinococcus multilocularis | musashi | 0.0055 | 0.0432 | 0.0655 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0072 | 0.0707 | 0.1348 |
Brugia malayi | ecdysteroid receptor | 0.0152 | 0.2057 | 0.2057 |
Echinococcus granulosus | serotonin transporter | 0.0235 | 0.3443 | 0.9369 |
Loa Loa (eye worm) | hypothetical protein | 0.0235 | 0.3443 | 0.3443 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0707 | 0.0707 |
Schistosoma mansoni | tyrosine kinase | 0.0046 | 0.0279 | 0.0251 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0152 | 0.2057 | 0.2057 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0075 | 0.0761 | 0.1372 |
Echinococcus multilocularis | serotonin transporter | 0.0235 | 0.3443 | 0.8227 |
Echinococcus granulosus | carboxylesterase 5A | 0.0066 | 0.0607 | 0.1248 |
Schistosoma mansoni | intermediate filament proteins | 0.0055 | 0.0432 | 0.0606 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0152 | 0.2057 | 0.2057 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0145 | 0.1933 | 0.443 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0072 | 0.0707 | 0.1348 |
Loa Loa (eye worm) | TK/EGFR protein kinase | 0.0145 | 0.1933 | 0.1933 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0152 | 0.2057 | 0.5399 |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 0.2057 | 0.2057 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0152 | 0.2057 | 0.5399 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0072 | 0.0707 | 0.0707 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0852 | 0.0852 |
Echinococcus multilocularis | carbonic anhydrase | 0.0082 | 0.0875 | 0.177 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0072 | 0.0702 | 0.1334 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0852 | 0.0852 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0294 | 0.0294 |
Schistosoma mansoni | tyrosine kinase | 0.0078 | 0.0808 | 0.1482 |
Brugia malayi | Blistered cuticle protein 3 | 0.0051 | 0.0359 | 0.0359 |
Plasmodium falciparum | carbonic anhydrase | 0.0082 | 0.0875 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0852 | 0.0852 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0152 | 0.2057 | 0.2057 |
Schistosoma mansoni | tyrosine kinase | 0.0145 | 0.1933 | 0.4098 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0852 | 0.0852 |
Brugia malayi | Serotonin receptor | 0.0473 | 0.7427 | 0.7427 |
Plasmodium falciparum | LCCL domain-containing protein | 0.0062 | 0.054 | 0.5243 |
Echinococcus granulosus | neurogenic locus notch protein | 0.0047 | 0.0294 | 0.0351 |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 0.2057 | 0.2057 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0075 | 0.0761 | 0.0761 |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 0.2057 | 0.2057 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0082 | 0.0875 | 0.1637 |
Schistosoma mansoni | glutaminase | 0.0296 | 0.447 | 1 |
Loa Loa (eye worm) | norepinephrine transporter | 0.0235 | 0.3443 | 0.3443 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0171 | 0.0171 |
Schistosoma mansoni | carbonic anhydrase | 0.0082 | 0.0875 | 0.1637 |
Brugia malayi | hypothetical protein | 0.0074 | 0.0742 | 0.0742 |
Schistosoma mansoni | lipoxygenase | 0.0241 | 0.3549 | 0.7857 |
Schistosoma mansoni | cell polarity protein | 0.0047 | 0.0294 | 0.0285 |
Schistosoma mansoni | tyrosine kinase | 0.0077 | 0.0794 | 0.145 |
Echinococcus multilocularis | mitogen activated protein kinase 14 | 0.0122 | 0.1555 | 0.3479 |
Brugia malayi | glutaminase DH11.1 | 0.0296 | 0.447 | 0.447 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0152 | 0.2057 | 0.4386 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.0742 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0761 | 0.0761 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.0174 | 0.2425 | 0.5242 |
Schistosoma mansoni | thyroid hormone receptor | 0.0277 | 0.4149 | 0.9252 |
Schistosoma mansoni | loxhd1 | 0.0062 | 0.054 | 0.0858 |
Brugia malayi | Animal haem peroxidase family protein | 0.0051 | 0.0359 | 0.0359 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0062 | 0.054 | 0.0928 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0078 | 0.0808 | 0.1602 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.004 | 0.0171 | 0.0171 |
Schistosoma mansoni | nuclear receptor | 0.0072 | 0.0707 | 0.1247 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.004 | 0.0171 | 0.0171 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0152 | 0.2057 | 0.4741 |
Onchocerca volvulus | 0.0152 | 0.2057 | 0.5763 | |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0152 | 0.2057 | 0.2057 |
Schistosoma mansoni | rab6-interacting | 0.0062 | 0.054 | 0.0858 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0072 | 0.0707 | 0.1535 |
Echinococcus multilocularis | carbonic anhydrase | 0.0082 | 0.0875 | 0.177 |
Echinococcus granulosus | carbonic anhydrase | 0.0082 | 0.0875 | 0.2015 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0607 | 0.0607 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0359 | 0.0359 |
Echinococcus granulosus | insulin receptor | 0.0046 | 0.0279 | 0.0309 |
Schistosoma mansoni | tyrosine kinase | 0.0077 | 0.0794 | 0.145 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription factor | 0.0246 | 0.3635 | 0.8709 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0152 | 0.2057 | 0.2057 |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 0.2057 | 0.2057 |
Brugia malayi | Sodium:neurotransmitter symporter family protein 1, putative | 0.004 | 0.0171 | 0.0171 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0145 | 0.1933 | 0.5045 |
Loa Loa (eye worm) | hypothetical protein | 0.0235 | 0.3443 | 0.3443 |
Schistosoma mansoni | lamin | 0.0055 | 0.0432 | 0.0606 |
Brugia malayi | conserved hypotetical protein | 0.0072 | 0.0707 | 0.0707 |
Plasmodium vivax | hypothetical protein, conserved | 0.0075 | 0.0761 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0707 | 0.0707 |
Echinococcus multilocularis | mitogen activated protein kinase 11 | 0.0122 | 0.1555 | 0.3479 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0707 | 0.0707 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0066 | 0.0607 | 0.0607 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.008 | 0.0852 | 0.0852 |
Brugia malayi | Doublecortin family protein | 0.0062 | 0.054 | 0.054 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0152 | 0.2057 | 0.2057 |
Echinococcus multilocularis | nuclear factor of activated T cells 5 | 0.0145 | 0.1926 | 0.4412 |
Onchocerca volvulus | 0.0072 | 0.0707 | 0.1638 | |
Echinococcus multilocularis | jun protein | 0.0246 | 0.3635 | 0.8709 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0707 | 0.0707 |
Echinococcus multilocularis | RUN | 0.0062 | 0.054 | 0.0928 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0152 | 0.2057 | 0.5763 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0072 | 0.0707 | 0.0707 |
Leishmania major | hypothetical protein, conserved | 0.0075 | 0.0761 | 0.0344 |
Loa Loa (eye worm) | hypothetical protein | 0.0626 | 1 | 1 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0062 | 0.054 | 0.1057 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0072 | 0.0702 | 0.0702 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0359 | 0.0359 |
Echinococcus multilocularis | neurogenic locus notch protein | 0.0047 | 0.0294 | 0.0308 |
Brugia malayi | nuclear receptor RXR | 0.008 | 0.0852 | 0.0852 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0235 | 0.3443 | 0.3443 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0072 | 0.0707 | 0.1247 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.008 | 0.0852 | 0.0852 |
Brugia malayi | Animal haem peroxidase family protein | 0.0051 | 0.0359 | 0.0359 |
Schistosoma mansoni | slit | 0.0064 | 0.057 | 0.0929 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0072 | 0.0707 | 0.1638 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.0742 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.008 | 0.0852 | 0.0852 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0235 | 0.3443 | 0.7611 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0152 | 0.2057 | 0.5763 |
Echinococcus granulosus | acetylcholinesterase | 0.0066 | 0.0607 | 0.1248 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0082 | 0.0875 | 0.1637 |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 0.2057 | 0.2057 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0072 | 0.0707 | 0.0707 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0152 | 0.2057 | 0.2057 |
Onchocerca volvulus | Peroxidase homolog | 0.0051 | 0.0359 | 0.0574 |
Echinococcus multilocularis | acetylcholinesterase | 0.0066 | 0.0607 | 0.1096 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0152 | 0.2057 | 0.2057 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0359 | 0.0359 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0125 | 0.1594 | 0.4074 |
Loa Loa (eye worm) | intermediate filament protein | 0.0055 | 0.0432 | 0.0432 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0072 | 0.0707 | 0.1348 |
Loa Loa (eye worm) | hypothetical protein | 0.0235 | 0.3443 | 0.3443 |
Echinococcus multilocularis | lamin dm0 | 0.0055 | 0.0432 | 0.0655 |
Schistosoma mansoni | hypothetical protein | 0.0082 | 0.0875 | 0.1637 |
Schistosoma mansoni | hypothetical protein | 0.0184 | 0.2582 | 0.5607 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0152 | 0.2057 | 0.2057 |
Brugia malayi | ecdysone receptor | 0.0072 | 0.0707 | 0.0707 |
Brugia malayi | intermediate filament protein | 0.0055 | 0.0432 | 0.0432 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0075 | 0.0761 | 0.0761 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0075 | 0.0761 | 0.0344 |
Echinococcus granulosus | carbonic anhydrase II | 0.0174 | 0.2425 | 0.6452 |
Schistosoma mansoni | peroxidasin | 0.0051 | 0.0359 | 0.0437 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0294 | 0.0294 |
Toxoplasma gondii | hypothetical protein | 0.0082 | 0.0875 | 1 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0152 | 0.2057 | 0.4386 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0072 | 0.0707 | 0.0707 |
Brugia malayi | Cytochrome P450 family protein | 0.0061 | 0.0517 | 0.0517 |
Brugia malayi | hypothetical protein | 0.008 | 0.0852 | 0.0852 |
Mycobacterium ulcerans | glutaminase | 0.0296 | 0.447 | 1 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0152 | 0.2057 | 0.4386 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0051 | 0.0359 | 0.0359 |
Echinococcus granulosus | FTZ F1 alpha | 0.0152 | 0.2057 | 0.5399 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0075 | 0.0761 | 0.1483 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0041 | 0.0196 | 0.0073 |
Brugia malayi | hypothetical protein | 0.004 | 0.0171 | 0.0171 |
Loa Loa (eye worm) | glutaminase 2 | 0.0296 | 0.447 | 0.447 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription factor | 0.0246 | 0.3635 | 0.9918 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0359 | 0.0359 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0072 | 0.0707 | 0.0707 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.0174 | 0.2425 | 0.5242 |
Echinococcus multilocularis | mitogen activated protein kinase 11 | 0.0122 | 0.1555 | 0.3479 |
Loa Loa (eye worm) | carbonic anhydrase 3 | 0.0174 | 0.2425 | 0.2425 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0072 | 0.0707 | 0.1535 |
Echinococcus granulosus | carbonic anhydrase | 0.0082 | 0.0875 | 0.2015 |
Loa Loa (eye worm) | hypothetical protein | 0.0062 | 0.054 | 0.054 |
Onchocerca volvulus | 0.0075 | 0.0761 | 0.1803 | |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.008 | 0.0852 | 0.1583 |
Brugia malayi | nuclear receptor NHR-88 | 0.0152 | 0.2057 | 0.2057 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0248 | 0.3664 | 0.8124 |
Echinococcus multilocularis | mitogen activated protein kinase 14 | 0.0122 | 0.1555 | 0.3479 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0359 | 0.0359 |
Leishmania major | mitogen-activated protein kinase 3, putative,map kinase 3, putative | 0.0122 | 0.1555 | 0.4951 |
Brugia malayi | hypothetical protein | 0.0072 | 0.0707 | 0.0707 |
Brugia malayi | Peroxidasin | 0.0051 | 0.0359 | 0.0359 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0072 | 0.0707 | 0.1348 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0152 | 0.2057 | 0.4741 |
Loa Loa (eye worm) | TK/INSR protein kinase | 0.0046 | 0.0279 | 0.0279 |
Echinococcus multilocularis | carbonic anhydrase | 0.0082 | 0.0875 | 0.177 |
Onchocerca volvulus | 0.0075 | 0.0761 | 0.1803 | |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0359 | 0.0359 |
Trypanosoma brucei | mitogen-activated protein kinase 3, putative | 0.0122 | 0.1555 | 0.4951 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0359 | 0.0359 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0152 | 0.2057 | 0.4386 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.008 | 0.0852 | 0.1711 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0152 | 0.2057 | 0.2057 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0062 | 0.054 | 0.1057 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0852 | 0.0852 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0051 | 0.0359 | 0.0359 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0072 | 0.0707 | 0.1247 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0082 | 0.0875 | 0.0875 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0072 | 0.0707 | 0.1535 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0152 | 0.2057 | 0.4741 |
Brugia malayi | Carboxylesterase family protein | 0.0066 | 0.0607 | 0.0607 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.0742 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.0046 | 0.0279 | 0.0251 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0235 | 0.3443 | 0.7611 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0707 | 0.0707 |
Schistosoma mansoni | hypothetical protein | 0.02 | 0.2861 | 0.6256 |
Trypanosoma cruzi | mitogen-activated protein kinase 3, putative | 0.0122 | 0.1555 | 0.4951 |
Onchocerca volvulus | Peroxidasin homolog | 0.0051 | 0.0359 | 0.0574 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0707 | 0.0707 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0761 | 0.0761 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.004 | 0.0171 | 0.0171 |
Echinococcus multilocularis | 0.0045 | 0.0254 | 0.021 | |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.0082 | 0.0875 | 0.0875 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0152 | 0.2057 | 0.4741 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0152 | 0.2057 | 0.4386 |
Echinococcus multilocularis | Polycystic kidney disease protein | 0.0062 | 0.054 | 0.0928 |
Schistosoma mansoni | nuclear hormone receptor | 0.0072 | 0.0707 | 0.1247 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0152 | 0.2057 | 0.2057 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0152 | 0.2057 | 0.4386 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0359 | 0.0359 |
Echinococcus multilocularis | geminin | 0.0184 | 0.2582 | 0.6061 |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 0.2057 | 0.2057 |
Brugia malayi | nuclear receptor NHR-67 | 0.0072 | 0.0707 | 0.0707 |
Loa Loa (eye worm) | hypothetical protein | 0.0428 | 0.6677 | 0.6677 |
Brugia malayi | beta-lactamase | 0.0075 | 0.0761 | 0.0761 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0359 | 0.0359 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.057 | 0.057 |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 0.2057 | 0.2057 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0707 | 0.0707 |
Loa Loa (eye worm) | Sodium:neurotransmitter symporter family protein | 0.004 | 0.0171 | 0.0171 |
Echinococcus granulosus | insulin growth factor 1 receptor beta | 0.0046 | 0.0279 | 0.0309 |
Loa Loa (eye worm) | DR-78 | 0.0072 | 0.0707 | 0.0707 |
Brugia malayi | Thrombospondin N-terminal -like domain containing protein | 0.0047 | 0.0294 | 0.0294 |
Schistosoma mansoni | rab6-interacting | 0.0062 | 0.054 | 0.0858 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0174 | 0.2425 | 0.2425 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0062 | 0.054 | 0.0928 |
Echinococcus multilocularis | peroxidasin | 0.0051 | 0.0359 | 0.0473 |
Treponema pallidum | sodium- and chloride- dependent transporter | 0.0235 | 0.3443 | 0.5 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0051 | 0.0359 | 0.0359 |
Brugia malayi | steroid hormone receptor | 0.0152 | 0.2057 | 0.2057 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0072 | 0.0702 | 0.1519 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Delta mean survival time (functional) | = 3.9 | Antimalarial activity of the compound was measured against mice infected with Plasmodium berghei by subcutaneous administraton of 20 mg/kg dose | ChEMBL. | 1404226 |
Delta mean survival time (functional) | = 5.7 | Antimalarial activity of the compound was measured in mice infected with Plasmodium berghei by subcutaneous administraton at 40 mg/kg | ChEMBL. | 1404226 |
Delta mean survival time (functional) | = 7.5 | Antimalarial activity was measured in mice infected with Plasmodium berghei by subcutaneous administraton of 80 mg/kg | ChEMBL. | 1404226 |
Delta mean survival time (functional) | = 8.8 | Antimalarial activity of the compound was measured against mice infected with Plasmodium berghei by subcutaneous administraton of 640 mg/kg dose | ChEMBL. | 1404226 |
Delta mean survival time (functional) | = 12.8 | Antimalarial activity measured in mice infected with Plasmodium berghei by subcutaneous administraton of 160 mg/kg | ChEMBL. | 1404226 |
Delta mean survival time (functional) | = 3.9 | Antimalarial activity of the compound was measured against mice infected with Plasmodium berghei by subcutaneous administraton of 20 mg/kg dose | ChEMBL. | 1404226 |
Delta mean survival time (functional) | = 5.7 | Antimalarial activity of the compound was measured in mice infected with Plasmodium berghei by subcutaneous administraton at 40 mg/kg | ChEMBL. | 1404226 |
Delta mean survival time (functional) | = 7.5 | Antimalarial activity was measured in mice infected with Plasmodium berghei by subcutaneous administraton of 80 mg/kg | ChEMBL. | 1404226 |
Delta mean survival time (functional) | = 8.8 | Antimalarial activity of the compound was measured against mice infected with Plasmodium berghei by subcutaneous administraton of 640 mg/kg dose | ChEMBL. | 1404226 |
Delta mean survival time (functional) | = 12.8 | Antimalarial activity measured in mice infected with Plasmodium berghei by subcutaneous administraton of 160 mg/kg | ChEMBL. | 1404226 |
No. of cured mice (functional) | = 2 | Antimalarial activity was measured in mice infected with Plasmodium berghei by subcutaneous administraton of 160 mg/kg | ChEMBL. | 1404226 |
No. of cured mice (functional) | = 4 | Antimalarial activity measured in mice infected with Plasmodium berghei by subcutaneous administraton of 640 mg/kg | ChEMBL. | 1404226 |
No. of cured mice (functional) | = 5 | Antimalarial activity measured against mice infected with Plasmodium berghei by subcutaneous administraton of 320 mg/kg dose | ChEMBL. | 1404226 |
No. of cured mice (functional) | = 2 | Antimalarial activity was measured in mice infected with Plasmodium berghei by subcutaneous administraton of 160 mg/kg | ChEMBL. | 1404226 |
No. of cured mice (functional) | = 4 | Antimalarial activity measured in mice infected with Plasmodium berghei by subcutaneous administraton of 640 mg/kg | ChEMBL. | 1404226 |
No. of cured mice (functional) | = 5 | Antimalarial activity measured against mice infected with Plasmodium berghei by subcutaneous administraton of 320 mg/kg dose | ChEMBL. | 1404226 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.