Detailed information for compound 2069262

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 314.385 | Formula: C16H22N6O
  • H donors: 1 H acceptors: 4 LogP: 0.77 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(N1CCCC(C1)n1cccn1)CCCNc1ncccn1
  • InChi: 1S/C16H22N6O/c23-15(6-1-7-17-16-18-8-3-9-19-16)21-11-2-5-14(13-21)22-12-4-10-20-22/h3-4,8-10,12,14H,1-2,5-7,11,13H2,(H,17,18,19)
  • InChiKey: DCWKKBAMOMFWMQ-UHFFFAOYSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0019 0.0056 0.0132
Schistosoma mansoni serine/threonine-protein kinase 0.0008 0.0011 0.0008
Echinococcus multilocularis transient receptor potential cation channel 0.0019 0.0056 0.0132
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.1057 0.4673 1
Giardia lamblia Fructose-bisphosphate aldolase 0.0153 0.0653 1
Loa Loa (eye worm) AGC/PKN protein kinase 0.0007 0.0004 0.0000046119
Trypanosoma brucei inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0086 0.0354 0.0758
Echinococcus multilocularis potassium voltage gated channel protein 0.0019 0.0056 0.0132
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0021 0.023
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0019 0.0056 0.0132
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0011 0.0023 0.0039
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0019 0.0056 0.0052
Loa Loa (eye worm) phosphatidylinositol 3 0.0015 0.0038 0.0049
Leishmania major phosphoinositide-specific phospholipase C, putative 0.0037 0.0136 0.0415
Schistosoma mansoni voltage-gated ion channel 0.0019 0.0056 0.0062
Trypanosoma cruzi cdc2-related kinase 1 0.0013 0.0031 0.0055
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0019 0.0056 0.0132
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0011 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0019 0.0056 0.0076
Trichomonas vaginalis PIKK family atypical protein kinase 0.001 0.0017 0.0173
Trypanosoma brucei cyclin 2 0.0008 0.0007 0.0015
Echinococcus granulosus voltage gated hydrogen channel 1 0.0019 0.0056 0.0132
Brugia malayi Transient-receptor-potential like protein 0.0019 0.0056 0.0052
Echinococcus multilocularis geminin 0.0394 0.1727 0.4356
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0075 0.0305 1
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0019 0.0056 0.0052
Trypanosoma brucei hypothetical protein, conserved 0.0007 0.0005 0.0011
Plasmodium falciparum LCCL domain-containing protein 0.001 0.0019 0.1213
Trypanosoma cruzi CYC2-like cyclin, putative 0.0008 0.0007 0.0004
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0077 0.0164
Trypanosoma brucei cdc2-related kinase 3 0.0013 0.0031 0.0066
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0019 0.0056 0.0132
Echinococcus multilocularis transient receptor potential cation channel 0.0019 0.0056 0.0132
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0153 0.0653 0.7709
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0313 0.0368
Trypanosoma brucei DNA damage repair protein, putative 0.0007 0.0005 0.0011
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0077 0.0164
Loa Loa (eye worm) hypothetical protein 0.0019 0.0056 0.0076
Echinococcus multilocularis ryanodine receptor 44f 0.0696 0.3066 0.7742
Echinococcus granulosus Protein kinase C brain isozyme 0.0033 0.0118 0.0288
Brugia malayi Phosphatidylinositol-specific phospholipase C, X domain containing protein 0.0025 0.0082 0.0079
Echinococcus multilocularis dna polymerase kappa 0.0023 0.0077 0.0184
Trichomonas vaginalis mercuric reductase, putative 0.0011 0.0023 0.0254
Echinococcus granulosus shaker cognate 0.0019 0.0056 0.0132
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0011 0.0023 0.005
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0019 0.0056 0.0062
Trichomonas vaginalis PIKK family atypical protein kinase 0.0008 0.0008 0.0072
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0011 0.0023 0.0049
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0012 0.0025 0.0053
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0019 0.0056 0.0132
Trichomonas vaginalis PIKK family atypical protein kinase 0.0009 0.0012 0.0117
Echinococcus granulosus serine/threonine protein kinase 0.0008 0.0011 0.0017
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0077 0.0164
Loa Loa (eye worm) hypothetical protein 0.0019 0.0056 0.0076
Toxoplasma gondii transporter, cation channel family protein 0.0019 0.0056 0.2271
Schistosoma mansoni inositol 145-trisphosphate receptor 0.1359 0.6015 0.7149
Brugia malayi RNA recognition motif domain containing protein 0.0076 0.0313 0.0309
Toxoplasma gondii phosphoinositide phospholipase PIPLC 0.0058 0.0229 1
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0019 0.0056 0.064
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0025 0.0269
Echinococcus multilocularis two pore calcium channel protein 2 0.0019 0.0056 0.0132
Schistosoma mansoni serine/threonine protein kinase 0.0013 0.0031 0.0032
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0013 0.0031 0.0039
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0056 0.0062
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0077 0.0153
Echinococcus multilocularis potassium large conductance calcium activated 0.0019 0.0056 0.0132
Echinococcus multilocularis ryanodine receptor 44f 0.0897 0.3958 1
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0013 0.0031 0.008
Entamoeba histolytica deoxycytidyl transferase, putative 0.0023 0.0077 0.0865
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0021 0.023
Brugia malayi p70 ribosomal S6 kinase beta 0.0011 0.0023 0.0019
Brugia malayi ImpB/MucB/SamB family protein 0.0023 0.0077 0.0073
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0056 0.0062
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0019 0.0056 0.0052
Echinococcus multilocularis lamin dm0 0.0033 0.0118 0.0288
Echinococcus multilocularis 1 phosphatidylinositol 4,5 bisphosphate 0.0059 0.0238 0.0591
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0019 0.0056 0.0062
Schistosoma mansoni loxhd1 0.001 0.0019 0.0018
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0011 0.0023 0.0605
Leishmania major hypothetical protein, conserved 0.0719 0.3168 1
Echinococcus multilocularis conserved hypothetical protein 0.0019 0.0056 0.0132
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0023 0.0077 0.0184
Echinococcus granulosus sodium channel protein 0.0019 0.0056 0.0132
Brugia malayi Hr1 repeat family protein 0.0007 0.0004 0.0000031851
Loa Loa (eye worm) hypothetical protein 0.0019 0.0056 0.0076
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0008 0.001 0.0006
Echinococcus granulosus cyclin dependent kinase 1 0.0013 0.0031 0.0068
Echinococcus multilocularis two pore calcium channel protein 1 0.0019 0.0056 0.0132
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0021 0.023
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0011 0.0023 0.0039
Echinococcus multilocularis RNA directed DNA polymerase 0.002 0.0064 0.0152
Loa Loa (eye worm) hypothetical protein 0.0019 0.0056 0.0076
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0011 0.0023 0.1606
Echinococcus granulosus Polycystic kidney disease protein 0.001 0.0019 0.0038
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0015 0.0038 0.0405
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0077 0.0164
Echinococcus granulosus transient receptor potential cation channel 0.0019 0.0056 0.0132
Echinococcus multilocularis transient receptor potential cation channel 0.0019 0.0056 0.0132
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0076 0.0313 0.0448
Echinococcus granulosus potassium voltage gated channel protein 0.0019 0.0056 0.0132
Loa Loa (eye worm) hypothetical protein 0.156 0.6907 1
Schistosoma mansoni hypothetical protein 0.0394 0.1727 0.2049
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0056 0.0062
Echinococcus multilocularis cytohesin 1 0.0091 0.0377 0.0944
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0019 0.0056 0.0052
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0153 0.0653 0.7709
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0021 0.023
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0019 0.0056 0.0132
Toxoplasma gondii thioredoxin reductase 0.0033 0.0118 0.5054
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0153 0.0653 0.7709
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0008 0.001 0.0006
Echinococcus multilocularis tar DNA binding protein 0.0076 0.0313 0.0782
Trypanosoma cruzi DNA polymerase eta, putative 0.0023 0.0077 0.0153
Echinococcus multilocularis stromal cell derived factor 2 0.0196 0.0846 0.213
Brugia malayi Protein kinase domain containing protein 0.0016 0.0045 0.0041
Echinococcus granulosus intermediate filament protein 0.0033 0.0118 0.0288
Toxoplasma gondii NADPH-glutathione reductase 0.0011 0.0023 0.0811
Schistosoma mansoni serine/threonine protein kinase 0.0007 0.0004 0.0000037865
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0019 0.0056 0.016
Trypanosoma cruzi phosphoinositide-specific phospholipase C, putative 0.0039 0.0146 0.0301
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0019 0.0056 0.0062
Trypanosoma brucei cdc2-related kinase 1 0.0013 0.0031 0.0066
Brugia malayi Protein kinase domain containing protein 0.0015 0.004 0.0036
Schistosoma mansoni hypothetical protein 0.001 0.0019 0.0018
Entamoeba histolytica protein kinase, putative 0.0015 0.004 0.0424
Brugia malayi TAR-binding protein 0.0076 0.0313 0.0309
Loa Loa (eye worm) hypothetical protein 0.1537 0.6805 0.9851
Loa Loa (eye worm) hypothetical protein 0.1359 0.6015 0.8707
Schistosoma mansoni voltage-dependent calcium channel 0.0019 0.0056 0.0062
Echinococcus multilocularis transient receptor potential gamma protein 0.0019 0.0056 0.0132
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0077 0.0153
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0019 0.0056 0.0132
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0011 0.0023 0.002
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0019 0.0056 0.0132
Schistosoma mansoni serine/threonine protein kinase 0.0033 0.0118 0.0136
Trypanosoma brucei DNA damage repair protein, putative 0.0007 0.0005 0.0011
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0019 0.0056 0.0132
Schistosoma mansoni polycystin 1-related 0.001 0.0019 0.0018
Trypanosoma cruzi cdc2-related kinase 1 0.0013 0.0031 0.0055
Echinococcus multilocularis RUN 0.001 0.0019 0.0038
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0011 0.0023 0.0057
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0019 0.0056 0.0062
Loa Loa (eye worm) hypothetical protein 0.0015 0.004 0.0053
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0029 0.0101 0.0247
Loa Loa (eye worm) intermediate filament protein 0.0033 0.0118 0.0165
Loa Loa (eye worm) hypothetical protein 0.0033 0.0118 0.0165
Echinococcus granulosus dna polymerase eta 0.0023 0.0077 0.0184
Giardia lamblia Kinase, CMGC CDK 0.0013 0.0031 0.0393
Trichomonas vaginalis CMGC family protein kinase 0.0013 0.0031 0.0341
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0019 0.0056 0.0132
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0019 0.0056 0.0132
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0019 0.0056 0.0062
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0019 0.0056 0.0062
Brugia malayi cation channel family protein 0.0019 0.0056 0.0052
Mycobacterium ulcerans DNA polymerase IV 0.0023 0.0077 0.2382
Leishmania major DNA polymerase eta, putative 0.0023 0.0077 0.0226
Plasmodium falciparum glutathione reductase 0.0011 0.0023 0.1606
Trypanosoma brucei phosphoinositide-specific phospholipase C 0.0039 0.0146 0.0312
Brugia malayi phospholipase C homolog 0.0043 0.0165 0.0161
Trypanosoma brucei DNA polymerase kappa, putative 0.0007 0.0005 0.0011
Echinococcus multilocularis short transient receptor potential channel 6 0.0019 0.0056 0.0132
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0011 0.0023 0.0039
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0038 0.0426
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0015 0.0038 0.0405
Echinococcus multilocularis short transient receptor potential channel 6 0.0019 0.0056 0.0132
Echinococcus multilocularis transient receptor potential cation channel 0.0019 0.0056 0.0132
Leishmania major inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0082 0.0337 0.105
Brugia malayi hypothetical protein 0.001 0.0019 0.0015
Onchocerca volvulus 0.0035 0.0127 0.1459
Plasmodium falciparum thioredoxin reductase 0.0011 0.0023 0.1606
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0015 0.0038 0.0034
Trypanosoma cruzi target of rapamycin kinase 3 0.0012 0.0025 0.0042
Schistosoma mansoni transient receptor potential channel 0.0019 0.0056 0.0062
Schistosoma mansoni two-pore calcium channel 0.0019 0.0056 0.0062
Onchocerca volvulus 0.001 0.0019 0.0182
Loa Loa (eye worm) cytohesin 3 0.0091 0.0377 0.0541
Echinococcus multilocularis voltage gated potassium channel 0.0019 0.0056 0.0132
Schistosoma mansoni atypical protein kinase C 0.001 0.0018 0.0017
Loa Loa (eye worm) Plcb4 protein 0.0057 0.0228 0.0325
Leishmania major phosphatidylinositol-specific phospholipase-like protein 0.0025 0.0082 0.0244
Trichomonas vaginalis DNA polymerase eta, putative 0.0023 0.0077 0.0885
Loa Loa (eye worm) hypothetical protein 0.0019 0.0056 0.0076
Trypanosoma brucei chrX additional, unordered contigs 0.0007 0.0005 0.0011
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0056 0.0062
Loa Loa (eye worm) hypothetical protein 0.0019 0.0056 0.0076
Echinococcus granulosus protein kinase c iota type 0.001 0.0018 0.0035
Trichomonas vaginalis AGC family protein kinase 0.0015 0.004 0.0445
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0011 0.0023 0.0039
Echinococcus granulosus serine:threonine protein kinase N2 0.0007 0.0004 0.0000080509
Trypanosoma cruzi inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0082 0.0337 0.0711
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0007 0.0004 0.0000080509
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0015 0.0038 0.0103
Entamoeba histolytica protein kinase, putative 0.0011 0.0023 0.0224
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0007 0.0004 0.0000046119
Plasmodium falciparum thioredoxin reductase 0.0033 0.0118 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0011 0.0023 0.0039
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0056 0.0062
Trypanosoma brucei unspecified product 0.0016 0.0045 0.0095
Trichomonas vaginalis AGC family protein kinase 0.0015 0.004 0.0445
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0056 0.0062
Schistosoma mansoni rab6-interacting 0.001 0.0019 0.0018
Schistosoma mansoni guanyl-nucleotide exchange factor 0.0091 0.0377 0.0444
Loa Loa (eye worm) hypothetical protein 0.0019 0.0056 0.0076
Brugia malayi Doublecortin family protein 0.001 0.0019 0.0015
Trypanosoma brucei unspecified product 0.0023 0.0077 0.0164
Brugia malayi Cyclic-nucleotide gated cation channel 0.0019 0.0056 0.0052
Brugia malayi Thioredoxin reductase 0.0033 0.0118 0.0114
Loa Loa (eye worm) hypothetical protein 0.0019 0.0056 0.0076
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0007 0.0004 0.0000080509
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0019 0.0056 0.0052
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0056 0.0062
Schistosoma mansoni lamin 0.0033 0.0118 0.0136
Schistosoma mansoni serine/threonine protein kinase 0.0033 0.0118 0.0136
Loa Loa (eye worm) hypothetical protein 0.0019 0.0056 0.0076
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0019 0.0056 0.0132
Echinococcus multilocularis musashi 0.0033 0.0118 0.0288
Brugia malayi Protein kinase domain containing protein 0.0007 0.0004 0.0000031851
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0007 0.0004 0.0000080509
Echinococcus multilocularis serine threonine protein kinase 0.0029 0.0104 0.0253
Brugia malayi intermediate filament protein 0.0033 0.0118 0.0114
Leishmania major phospholipase c-like protein 0.0039 0.0146 0.0445
Loa Loa (eye worm) hypothetical protein 0.0019 0.0056 0.0076
Loa Loa (eye worm) hypothetical protein 0.002 0.0064 0.0087
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0019 0.0056 0.0132
Trichomonas vaginalis PIKK family atypical protein kinase 0.0008 0.0008 0.0072
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0153 0.0653 0.7709
Schistosoma mansoni serine/threonine protein kinase 0.0012 0.0027 0.0028
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0019 0.0056 0.0132
Echinococcus granulosus 1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-4 0.0059 0.0238 0.0591
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0077 0.0164
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0019 0.0056 0.0132
Trypanosoma brucei trypanothione reductase 0.0033 0.0118 0.0253
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0016 0.0043 0.0099
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0056 0.0062
Schistosoma mansoni lamin 0.0033 0.0118 0.0136
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0011 0.0023 0.0605
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0077 0.0164
Toxoplasma gondii target of rapamycin (TOR), putative 0.0011 0.0021 0.0719
Echinococcus granulosus calcium activated potassium channel 0.0019 0.0058 0.0137
Brugia malayi ImpB/MucB/SamB family protein 0.0023 0.0077 0.0073
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0077 0.0164
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0016 0.0045 0.0059
Echinococcus granulosus lamin dm0 0.0033 0.0118 0.0288
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0016 0.0045 0.0059
Loa Loa (eye worm) hypothetical protein 0.0035 0.0127 0.0178
Echinococcus granulosus sodium leak channel non selective protein 0.0019 0.0056 0.0132
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0007 0.0004 0.0000080509
Schistosoma mansoni transient receptor potential channel 0.0019 0.0056 0.0062
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0019 0.0056 0.062
Loa Loa (eye worm) hypothetical protein 0.0019 0.0056 0.0076
Echinococcus granulosus potassium voltage gated channel protein 0.0019 0.0056 0.0132
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0019 0.0056 0.062
Echinococcus multilocularis potassium voltage gated channel protein 0.0019 0.0056 0.0132
Echinococcus granulosus potassium large conductance calcium activated 0.0019 0.0056 0.0132
Toxoplasma gondii cyclin2 related protein 0.0008 0.0007 0.008
Loa Loa (eye worm) ion channel NompC 0.0019 0.0056 0.0076
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0015 0.0038 0.0081
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0023 0.0077 0.0226
Loa Loa (eye worm) hypothetical protein 0.001 0.0019 0.0022
Echinococcus granulosus short transient receptor potential channel 6 0.0019 0.0056 0.0132
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0153 0.0653 0.7704
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0007 0.006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0009 0.0011 0.0113
Echinococcus granulosus transient receptor potential cation channel 0.0019 0.0056 0.0132
Loa Loa (eye worm) voltage-dependent calcium channel 0.0019 0.0056 0.0076
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0019 0.0056 0.0052
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0313 0.0368
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0019 0.0056 0.0052
Loa Loa (eye worm) ryanodine receptor 0.0339 0.1478 0.2135
Echinococcus multilocularis serine:threonine protein kinase 38 0.0007 0.0004 0.0000080509
Echinococcus multilocularis protein kinase c iota type 0.001 0.0018 0.0035
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0025 0.0269
Trypanosoma brucei DNA polymerase eta, putative 0.0023 0.0077 0.0164
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0015 0.0038 0.0041
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0023 0.0075 0.0103
Trypanosoma cruzi trypanothione reductase, putative 0.0011 0.0023 0.0039
Loa Loa (eye worm) voltage-gated calcium channel 0.0019 0.0056 0.0076
Schistosoma mansoni transient receptor potential channel 4 0.0019 0.0056 0.0062
Loa Loa (eye worm) hypothetical protein 0.0019 0.0056 0.0076
Plasmodium vivax glutathione reductase, putative 0.0033 0.0118 1
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0019 0.0056 0.0052
Echinococcus multilocularis voltage gated potassium channel 0.0019 0.0056 0.0132
Trichomonas vaginalis AGC family protein kinase 0.0007 0.0004 0.0023
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.1254 0.5546 0.5545
Entamoeba histolytica PH domain containing protein kinase, putative 0.0008 0.0011 0.0081
Loa Loa (eye worm) calcium channel 0.0019 0.0056 0.0076
Loa Loa (eye worm) doublecortin family protein 0.001 0.0019 0.0022
Leishmania major CYC2-like cyclin, putative 0.0008 0.0007 0.0006
Brugia malayi polk-prov protein 0.0007 0.0005 0.0001
Plasmodium falciparum glutathione reductase 0.0033 0.0118 1
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0019 0.0056 0.0052
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0016 0.0045 0.0103
Toxoplasma gondii transporter, cation channel family protein 0.0019 0.0056 0.2271
Trichomonas vaginalis AGC family protein kinase 0.0016 0.0045 0.0505
Leishmania major trypanothione reductase 0.0033 0.0118 0.0357
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0023 0.0077 0.1892
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0013 0.0031 0.0068
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0056 0.0062
Echinococcus granulosus stromal cell derived factor 2 0.0196 0.0846 0.213
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0019 0.0056 0.0052
Loa Loa (eye worm) hypothetical protein 0.0019 0.0056 0.0076
Onchocerca volvulus 0.0019 0.0056 0.062
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0019 0.0056 0.0052
Trypanosoma brucei CYC2-like cyclin, putative 0.0008 0.0007 0.0015
Trichomonas vaginalis AGC family protein kinase 0.0016 0.0045 0.0505
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0153 0.0653 0.7709
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0019 0.0056 0.0062
Loa Loa (eye worm) hypothetical protein 0.0019 0.0056 0.0076
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0075 0.0305 1
Brugia malayi glutathione reductase 0.0033 0.0118 0.0114
Loa Loa (eye worm) hypothetical protein 0.0019 0.0056 0.0076
Echinococcus granulosus short transient receptor potential channel 6 0.0019 0.0056 0.0132
Giardia lamblia Kinase, CMGC CDK 0.0013 0.0031 0.0393
Brugia malayi phosphoinositide-dependent protein kinase I 0.0016 0.0045 0.0041
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0007 0.0004 0.0008
Onchocerca volvulus 0.0102 0.0429 0.5042
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0019 0.0056 0.0132
Echinococcus multilocularis hyperpolarization activated cyclic 0.0019 0.0056 0.0132
Onchocerca volvulus 0.0072 0.0292 0.3416
Echinococcus multilocularis transient receptor potential cation channel 0.0019 0.0056 0.0132
Plasmodium falciparum cyclin, putative 0.0008 0.0007 0.0159
Plasmodium vivax thioredoxin reductase, putative 0.0033 0.0118 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0021 0.023
Echinococcus granulosus thioredoxin glutathione reductase 0.0033 0.0118 0.0289
Trypanosoma cruzi cdc2-related kinase 3 0.0013 0.0031 0.0055
Trichomonas vaginalis PIKK family atypical protein kinase 0.0008 0.0008 0.0073
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0019 0.0056 0.0062
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0313 0.0368
Trichomonas vaginalis AGC family protein kinase 0.0015 0.004 0.0445
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0045 0.0095
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0077 0.0153
Echinococcus multilocularis potassium voltage gated channel protein 0.0019 0.0056 0.0132
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0153 0.0653 0.7709
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0015 0.0038 0.007
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0045 0.0095
Echinococcus granulosus tar DNA binding protein 0.0076 0.0313 0.0782
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0056 0.0062
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0056 0.0062
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0028 0.0314
Loa Loa (eye worm) hypothetical protein 0.0094 0.0391 0.0561
Loa Loa (eye worm) hypothetical protein 0.0019 0.0056 0.0076
Loa Loa (eye worm) AGC/NDR protein kinase 0.0007 0.0004 0.0000046119
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0008 0.0011 0.0012
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0013 0.0031 0.008
Loa Loa (eye worm) phosphatidylinositol-specific phospholipase C 0.007 0.0283 0.0404
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0045 0.0095
Echinococcus multilocularis potassium voltage gated channel protein 0.0019 0.0056 0.0132
Brugia malayi Cytohesin 3 0.0091 0.0377 0.0374
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0019 0.0056 0.0132
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0011 0.0023 0.005
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0077 0.0164
Schistosoma mansoni serine/threonine kinase 0.0007 0.0004 0.0000037865
Mycobacterium tuberculosis Conserved hypothetical protein 0.0023 0.0077 0.1892
Echinococcus multilocularis microtubule associated protein 2 0.0361 0.1578 0.3981
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0019 0.0056 0.064
Entamoeba histolytica cell division protein kinase 2, putative 0.0013 0.0031 0.0319
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0012 0.0027 0.0034
Schistosoma mansoni transient receptor potential channel 0.0019 0.0056 0.0062
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0019 0.0056 0.0132
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0015 0.0038 0.007
Brugia malayi Phosphatidylinositol-specific phospholipase C, X domain containing protein 0.001 0.0019 0.0015
Loa Loa (eye worm) hypothetical protein 0.0082 0.0337 0.0483
Trichomonas vaginalis PIKK family atypical protein kinase 0.0008 0.0008 0.0073
Trichomonas vaginalis AGC family protein kinase 0.0007 0.0004 0.0023
Echinococcus multilocularis sodium leak channel non selective protein 0.0019 0.0056 0.0132
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0019 0.0056 0.0132
Trypanosoma cruzi CYC2-like cyclin 4, putative 0.0008 0.0007 0.0004
Onchocerca volvulus 0.001 0.0019 0.018
Loa Loa (eye worm) hypothetical protein 0.0019 0.0056 0.0076
Loa Loa (eye worm) variant SH3 domain-containing protein 0.003 0.0109 0.0152
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0011 0.0023 0.0039
Trichomonas vaginalis mannosyltransferase 1, putative 0.0196 0.0846 1
Echinococcus multilocularis serine:threonine protein kinase N2 0.0007 0.0004 0.0000080509
Trichomonas vaginalis PIKK family atypical protein kinase 0.0009 0.0012 0.0117
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0021 0.023
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0019 0.0056 0.0062
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0019 0.0056 0.0132
Loa Loa (eye worm) TAR-binding protein 0.0076 0.0313 0.0448
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0019 0.0056 0.0062
Echinococcus multilocularis calcium activated potassium channel 0.0019 0.0058 0.0137
Echinococcus multilocularis voltage dependent calcium channel 0.0019 0.0056 0.0132
Loa Loa (eye worm) thioredoxin reductase 0.0033 0.0118 0.0166
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0153 0.0653 0.7704
Trichomonas vaginalis AGC family protein kinase 0.0011 0.0021 0.0222
Trypanosoma brucei DNA polymerase kappa, putative 0.0007 0.0005 0.0011
Loa Loa (eye worm) glutathione reductase 0.0033 0.0118 0.0166
Loa Loa (eye worm) hypothetical protein 0.0015 0.004 0.0053
Schistosoma mansoni stromal cell-derived factor 2 precursor-like protein 0.0196 0.0846 0.1002
Echinococcus multilocularis lipoxygenase domain containing protein 0.001 0.0019 0.0038
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0056 0.0062
Giardia lamblia GTOR 0.0015 0.0038 0.0505
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0019 0.0056 0.0062
Schistosoma mansoni inositol 145-trisphosphate receptor 0.1898 0.8412 1
Echinococcus granulosus two pore calcium channel protein 1 0.0019 0.0056 0.0132
Schistosoma mansoni serine/threonine-protein kinase 0.0008 0.0011 0.0008
Echinococcus granulosus cyclin dependent kinase 5 0.0013 0.0031 0.0068
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0075 0.0305 1
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0033 0.0118 0.0288
Loa Loa (eye worm) hypothetical protein 0.0025 0.0082 0.0114
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0007 0.0004 0.0000080509
Echinococcus granulosus lipoxygenase domain containing protein 0.001 0.0019 0.0038
Schistosoma mansoni lipoxygenase 0.001 0.0019 0.0018
Loa Loa (eye worm) hypothetical protein 0.0016 0.0043 0.0057
Schistosoma mansoni phospholipase C-like protein 2 plc-L2 0.0051 0.0199 0.0233
Echinococcus multilocularis Polycystic kidney disease protein 0.001 0.0019 0.0038
Plasmodium vivax phospholipase C-like, putative 0.0025 0.0082 0.6828
Echinococcus multilocularis cyclin dependent kinase 1 0.0013 0.0031 0.0068
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0019 0.0056 0.0132
Toxoplasma gondii AGC kinase 0.0011 0.0023 0.0781
Trichomonas vaginalis AGC family protein kinase 0.0015 0.004 0.0445
Schistosoma mansoni microtubule-associated protein tau 0.0361 0.1578 0.1872
Echinococcus granulosus ryanodine receptor 44f 0.0696 0.3066 0.7742
Plasmodium vivax cyclin, putative 0.0008 0.0007 0.0159
Schistosoma mansoni voltage-gated cation channel 0.0019 0.0056 0.0062
Schistosoma mansoni serine/threonine protein kinase 0.0013 0.0031 0.0032
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0019 0.0056 0.0132
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0011 0.0023 0.005
Echinococcus multilocularis transfer RNA-Gly 0.0019 0.0056 0.0132
Loa Loa (eye worm) hypothetical protein 0.0023 0.0077 0.0106
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0019 0.0056 0.012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0038 0.0426
Echinococcus granulosus protein kinase C gamma type 0.0029 0.0104 0.0253
Echinococcus granulosus voltage dependent calcium channel 0.0019 0.0056 0.0132
Entamoeba histolytica PH domain containing protein kinase, putative 0.0008 0.0011 0.0081
Leishmania major DNA polymerase kappa, putative 0.0023 0.0077 0.0226
Brugia malayi hypothetical protein 0.001 0.0019 0.0015
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0019 0.0056 0.0132
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0019 0.0056 0.0062
Schistosoma mansoni ryanodine receptor 1 skeletal muscle 0.0339 0.1478 0.1753
Echinococcus granulosus hypothetical protein 0.0019 0.0056 0.0132
Echinococcus granulosus protein kinase c epsilon type 0.0012 0.0027 0.0059
Echinococcus granulosus RNA directed DNA polymerase 0.002 0.0064 0.0152
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0019 0.0056 0.2271
Loa Loa (eye worm) RNA binding protein 0.0076 0.0313 0.0448
Loa Loa (eye worm) hypothetical protein 0.0007 0.0005 0.0002
Echinococcus multilocularis lamin 0.0033 0.0118 0.0288
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0033 0.0118 0.3366
Loa Loa (eye worm) hypothetical protein 0.001 0.0019 0.0022
Brugia malayi RNA binding protein 0.0076 0.0313 0.0309
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0019 0.0056 0.2271
Loa Loa (eye worm) hypothetical protein 0.0897 0.3958 0.5728
Loa Loa (eye worm) AGC/AKT protein kinase 0.0015 0.004 0.0052
Trichomonas vaginalis 1-phosphatidylinositol phosphodiesterase, putative 0.001 0.0019 0.0204
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0077 0.0164
Loa Loa (eye worm) hypothetical protein 0.0082 0.0337 0.0483
Schistosoma mansoni lipoxygenase 0.0029 0.0101 0.0116
Echinococcus granulosus transient receptor potential cation channel 0.0019 0.0056 0.0132
Entamoeba histolytica MIR domain protein 0.0196 0.0846 1
Echinococcus granulosus cyclin dependent kinase 0.0013 0.0031 0.0068
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0019 0.0056 0.0062
Echinococcus granulosus transient receptor potential gamma protein 0.0019 0.0056 0.0132
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0023 0.0077 0.0106
Brugia malayi Phosphatidylinositol-specific phospholipase C, X domain containing protein 0.007 0.0283 0.0279
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0019 0.0056 0.0132
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0021 0.023
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0056 0.0062
Entamoeba histolytica protein kinase, putative 0.0016 0.0045 0.0484
Schistosoma mansoni rab6-interacting 0.001 0.0019 0.0018
Plasmodium vivax protein kinase Crk2 0.0013 0.0031 0.2253
Echinococcus multilocularis voltage dependent calcium channel 0.0019 0.0056 0.0132
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0019 0.0056 0.0132
Echinococcus multilocularis cyclin dependent kinase 5 0.0013 0.0031 0.0068
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0019 0.0056 0.0076
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0011 0.0023 0.0049
Echinococcus granulosus potassium voltage gated channel protein 0.0019 0.0056 0.0132
Loa Loa (eye worm) hypothetical protein 0.0059 0.0238 0.0339
Schistosoma mansoni serine/threonine protein kinase 0.0007 0.0004 0.0000037865
Echinococcus multilocularis lipoxygenase domain containing protein 0.001 0.0019 0.0038
Brugia malayi Protein kinase domain containing protein 0.0013 0.0031 0.0027
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0011 0.0023 0.5
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0023 0.0077 0.0087
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0077 0.0164
Loa Loa (eye worm) MIR domain-containing protein 0.0196 0.0846 0.122
Echinococcus multilocularis protein kinase c epsilon type 0.0012 0.0027 0.0059
Trichomonas vaginalis AGC family protein kinase 0.0016 0.0045 0.0505
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0016 0.0045 0.0103
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0013 0.0031 0.0039
Trichomonas vaginalis AGC family protein kinase 0.0015 0.004 0.0445
Echinococcus granulosus microtubule associated protein 2 0.0361 0.1578 0.3981
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0019 0.0056 0.0052
Echinococcus granulosus lipoxygenase domain containing protein 0.001 0.0019 0.0038
Onchocerca volvulus 0.0033 0.0118 0.1354
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0153 0.0653 0.7709
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0011 0.0023 0.1606
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0011 0.0023 0.0039
Echinococcus multilocularis serine:threonine protein kinase N2 0.0007 0.0004 0.0000080509
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0019 0.0056 0.0062
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0019 0.0056 0.0062
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0011 0.0023 0.1606
Echinococcus granulosus NDR protein kinase 0.0007 0.0004 0.0000080509
Trichomonas vaginalis CMGC family protein kinase 0.0013 0.0031 0.0341
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0011 0.0023 0.5
Plasmodium vivax multidomain scavenger receptor, putative 0.001 0.0019 0.1213
Brugia malayi voltage-dependent calcium channel 0.0019 0.0056 0.0052
Schistosoma mansoni DNA polymerase IV / kappa 0.0007 0.0005 0.0002
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0016 0.0043 0.0099
Loa Loa (eye worm) hypothetical protein 0.0024 0.0078 0.0107
Mycobacterium ulcerans DNA polymerase IV 0.0023 0.0077 0.2382
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0056 0.0062
Echinococcus multilocularis shaker cognate 0.0019 0.0056 0.0132
Brugia malayi cell division control protein 2 homolog 0.0013 0.0031 0.0027
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0019 0.0056 0.0132
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0011 0.0023 0.0057
Toxoplasma gondii transporter, cation channel family protein 0.0019 0.0056 0.2271
Trichomonas vaginalis PIKK family atypical protein kinase 0.0009 0.0011 0.0113
Loa Loa (eye worm) hypothetical protein 0.0013 0.0029 0.0036
Loa Loa (eye worm) hypothetical protein 0.0019 0.0056 0.0076
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0019 0.0056 0.0132
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0012 0.0025 0.0062
Brugia malayi Protein kinase domain containing protein 0.0007 0.0004 0.0000031851
Entamoeba histolytica cell division protein kinase 2, putative 0.0013 0.0031 0.0319
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0019 0.0056 0.0132
Toxoplasma gondii hypothetical protein 0.0019 0.0056 0.2271
Brugia malayi MIR domain containing protein 0.0196 0.0846 0.0843
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0077 0.0153
Echinococcus granulosus potassium voltage gated channel protein 0.0019 0.0056 0.0132
Loa Loa (eye worm) phosphatidylinositol-specific phospholipase C 0.001 0.0019 0.0022
Brugia malayi protein kinase C II. 0.0012 0.0027 0.0023
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0015 0.0038 0.0081
Trypanosoma cruzi CYC2-like cyclin 6, putative 0.0008 0.0007 0.0004
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0019 0.0056 0.0076
Giardia lamblia DINP protein human, muc B family 0.0023 0.0077 0.1103
Echinococcus multilocularis sodium channel protein 0.0019 0.0056 0.0132
Schistosoma mansoni phospholipase C beta 0.0057 0.0228 0.0267
Echinococcus granulosus TRP transient receptor potential channel 0.0019 0.0056 0.0132
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0019 0.0056 0.0052
Trichomonas vaginalis glutathione reductase, putative 0.0011 0.0023 0.0254
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0011 0.0023 0.5
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0011 0.0023 0.0027
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0077 0.0164
Echinococcus granulosus transient receptor potential cation channel 0.0019 0.0056 0.0132
Leishmania major hypothetical protein, unknown function 0.0019 0.0056 0.016
Schistosoma mansoni phospholipase C-like protein 2 plc-L2 0.0043 0.0165 0.0191
Echinococcus granulosus transient receptor potential cation channel 0.0019 0.0056 0.0132
Loa Loa (eye worm) hypothetical protein 0.0032 0.0115 0.0161
Trypanosoma brucei glycosylphosphatidylinositol-specific phospholipase C 0.001 0.0019 0.0041
Echinococcus multilocularis hyperpolarization activated cyclic 0.0019 0.0056 0.0132
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0019 0.0056 0.0062
Trichomonas vaginalis PIKK family atypical protein kinase 0.0008 0.0008 0.0073
Loa Loa (eye worm) hypothetical protein 0.0082 0.0337 0.0483
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0015 0.0038 0.0086
Echinococcus granulosus RUN 0.001 0.0019 0.0038
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0011 0.0023 0.005
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0077 0.0164
Trichomonas vaginalis PIKK family atypical protein kinase 0.0008 0.0008 0.0072
Plasmodium falciparum protein kinase 5 0.0013 0.0031 0.2253
Loa Loa (eye worm) voltage-gated potassium channel 0.0019 0.0056 0.0076
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0007 0.0004 0.0000080509
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0056 0.0062
Schistosoma mansoni hypothetical protein 0.0394 0.1727 0.2049
Brugia malayi ion channel NompC 0.0019 0.0056 0.0052
Schistosoma mansoni vesicular amine transporter 0.0019 0.0056 0.0062
Schistosoma mansoni ryanodine receptor related 0.1254 0.5546 0.6591
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0019 0.0056 0.0052
Trichomonas vaginalis AGC family protein kinase 0.0007 0.0004 0.0023
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0313 0.0368
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0056 0.0062
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0025 0.0269
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0019 0.0056 0.0132
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0011 0.0023 0.0039
Brugia malayi olfactory channel protein osm-9 0.0019 0.0056 0.0052
Brugia malayi Variant SH3 domain containing protein 0.003 0.0109 0.0105
Trypanosoma cruzi inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0082 0.0337 0.0711
Echinococcus granulosus hyperpolarization activated cyclic 0.0019 0.0056 0.0132
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0019 0.0056 0.0132
Treponema pallidum fructose-bisphosphate aldolase 0.0153 0.0653 1
Trichomonas vaginalis AGC family protein kinase 0.0015 0.004 0.0445
Trichomonas vaginalis PIKK family atypical protein kinase 0.0009 0.0012 0.0117
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0153 0.0653 0.7709
Echinococcus multilocularis transient receptor potential cation channel 0.0019 0.0056 0.0132
Schistosoma mansoni calcium-activated potassium channel 0.0019 0.0056 0.0062
Giardia lamblia NADH oxidase lateral transfer candidate 0.0011 0.0023 0.028
Echinococcus multilocularis cyclin dependent kinase 1 0.0013 0.0031 0.0068
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0023 0.0077 0.0885
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0011 0.0023 0.0811
Schistosoma mansoni phospholipase C beta 0.001 0.0019 0.0018
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0011 0.0023 0.0057
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0023 0.0077 0.0184
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0015 0.0038 0.0103
Trypanosoma brucei hypothetical protein, conserved 0.0007 0.0005 0.0011
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0019 0.0056 0.0076
Echinococcus multilocularis dna polymerase eta 0.0023 0.0077 0.0184
Trichomonas vaginalis AGC family protein kinase 0.0015 0.004 0.0445
Schistosoma mansoni serine/threonine protein kinase 0.0016 0.0045 0.0049
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0033 0.0118 0.0165
Trypanosoma brucei rac serine-threonine kinase, putative 0.0015 0.004 0.0085
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.1057 0.4673 1
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0011 0.0023 0.1606
Trichomonas vaginalis PIKK family atypical protein kinase 0.0008 0.0008 0.0073
Echinococcus multilocularis rac serine:threonine kinase 0.0008 0.0011 0.0017
Loa Loa (eye worm) hypothetical protein 0.0007 0.0004 0.0000046119
Onchocerca volvulus 0.0196 0.0846 1
Trypanosoma cruzi Protein kinase B 0.0008 0.0011 0.0012
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0019 0.0056 0.0109
Brugia malayi 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 4 0.0057 0.0228 0.0224
Echinococcus granulosus voltage gated potassium channel 0.0019 0.0056 0.0132
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0056 0.0062
Echinococcus multilocularis thioredoxin glutathione reductase 0.0033 0.0118 0.0289
Echinococcus granulosus lamin 0.0033 0.0118 0.0288
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0025 0.0269
Echinococcus granulosus geminin 0.0394 0.1727 0.4356
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0077 0.0164
Onchocerca volvulus 0.0033 0.0118 0.1354
Schistosoma mansoni hypothetical protein 0.0019 0.0056 0.0062
Loa Loa (eye worm) hypothetical protein 0.0019 0.0056 0.0076
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0007 0.0004 0.0000046119
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.002 0.0064 0.0152
Brugia malayi hypothetical protein 0.0019 0.0056 0.0052
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0017 0.0051 0.0068
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0011 0.0023 0.0605
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0056 0.0062
Schistosoma mansoni terminal deoxycytidyl transferase 0.0023 0.0077 0.0087
Echinococcus granulosus voltage dependent calcium channel 0.0019 0.0056 0.0132
Loa Loa (eye worm) hypothetical protein 0.0019 0.0056 0.0076
Echinococcus granulosus voltage gated potassium channel 0.0019 0.0056 0.0132
Loa Loa (eye worm) voltage-gated potassium channel 0.0019 0.0056 0.0076
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0038 0.0426
Trypanosoma cruzi trypanothione reductase, putative 0.0033 0.0118 0.0242
Trypanosoma brucei unspecified product 0.0016 0.0045 0.0095
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0015 0.0038 0.0086
Plasmodium falciparum phosphoinositide-specific phospholipase C 0.0025 0.0082 0.6828
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0313 0.0368
Brugia malayi phospholipase C homolog 0.0016 0.0046 0.0042
Trypanosoma cruzi cdc2-related kinase 3 0.0013 0.0031 0.0055
Schistosoma mansoni serine/threonine protein kinase 0.0007 0.0004 0.0000037865
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0019 0.0056 0.0132
Echinococcus granulosus cytohesin 1 0.0091 0.0377 0.0944
Schistosoma mansoni 60S ribosomal protein L21 0.0019 0.0056 0.0062
Leishmania major hypothetical protein, conserved 0.001 0.0019 0.0044
Entamoeba histolytica protein kinase, putative 0.0015 0.004 0.0424
Trichomonas vaginalis PIKK family atypical protein kinase 0.0009 0.0015 0.0157
Toxoplasma gondii cyclin, N-terminal domain-containing protein 0.0008 0.0007 0.008
Schistosoma mansoni DNA polymerase eta 0.0023 0.0077 0.0087
Echinococcus granulosus two pore calcium channel protein 2 0.0019 0.0056 0.0132
Echinococcus multilocularis cyclin dependent kinase 0.0013 0.0031 0.0068
Schistosoma mansoni serine/threonine protein kinase 0.0007 0.0004 0.0000037865
Trichomonas vaginalis CMGC family protein kinase 0.0013 0.0031 0.0341
Schistosoma mansoni intermediate filament proteins 0.0033 0.0118 0.0136
Trichomonas vaginalis 1-phosphatidylinositol phosphodiesterase, putative 0.001 0.0019 0.0204
Brugia malayi cytoplasmic intermediate filament protein 0.0017 0.0051 0.0047
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0007 0.0004 0.0000046119
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0029 0.0101 0.0247
Echinococcus granulosus potassium voltage gated channel protein 0.0019 0.0056 0.0132
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0019 0.0056 0.0132
Brugia malayi Intermediate filament tail domain containing protein 0.0033 0.0118 0.0114
Echinococcus granulosus ryanodine receptor 44f 0.0897 0.3958 1
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0019 0.0056 0.0132
Echinococcus granulosus transient receptor potential cation channel 0.0019 0.0056 0.0132
Brugia malayi Protein kinase c protein 2 0.0026 0.0089 0.0085
Onchocerca volvulus 0.001 0.0019 0.018
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0025 0.0269
Loa Loa (eye worm) ryanodine receptor 0.0019 0.0056 0.0076
Toxoplasma gondii hypothetical protein 0.0019 0.0056 0.2271
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0013 0.0031 0.1139
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0019 0.0056 0.0132
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0011 0.0023 0.0057
Echinococcus granulosus dna polymerase kappa 0.0023 0.0077 0.0184
Echinococcus granulosus hyperpolarization activated cyclic 0.0019 0.0056 0.0132
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0013 0.0031 0.0039

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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