TDR Targets

Basic information

Technical information

TDR Targets ID: 277394
Name: [2,6-di(propan-2-yl)phenyl] 3-[2,6-bis(dimeth ylamino)anilino]-3-oxopropanoate
MW: 425.564 | Formula: C25H35N3O3
H donors: 1 H acceptors: 2 LogP: 5.73 Rotable bonds: 10
Rule of 5 violations (Lipinski): 1
SMILES: O=C(Nc1c(cccc1N(C)C)N(C)C)CC(=O)Oc1c(cccc1C(C)C)C(C)C
InChi: 1S/C25H35N3O3/c1-16(2)18-11-9-12-19(17(3)4)25(18)31-23(30)15-22(29)26-24-20(27(5)6)13-10-14-21(24)28(7)8/h9-14,16-17H,15H2,1-8H3,(H,26,29)
InChiKey: DBAZMVZJGJPOCS-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

(2,6-diisopropylphenyl) 3-[2,6-bis(dimethylamino)anilino]-3-oxo-propanoate
3-[2,6-bis(dimethylamino)anilino]-3-oxopropanoic acid (2,6-diisopropylphenyl) ester
[2,6-di(propan-2-yl)phenyl] 3-[[2,6-bis(dimethylamino)phenyl]amino]-3-oxo-propanoate
3-[2,6-bis(dimethylamino)anilino]-3-keto-propionic acid (2,6-diisopropylphenyl) ester
[2,6-di(propan-2-yl)phenyl] 3-[[2,6-bis(dimethylamino)phenyl]amino]-3-oxopropanoate
(2,6-diisopropylphenyl) 3-[[2,6-bis(dimethylamino)phenyl]amino]-3-oxo-propanoate
3-[[2,6-bis(dimethylamino)phenyl]amino]-3-oxopropanoic acid (2,6-diisopropylphenyl) ester
3-[[2,6-bis(dimethylamino)phenyl]amino]-3-keto-propionic acid (2,6-diisopropylphenyl) ester

Targets

Known targets for this compound

Species	Target name	Source	Bibliographic reference
Oryctolagus cuniculus	Acyl-CoA:cholesterol acyltransferase	Starlite/ChEMBL	No references

Predicted pathogen targets for this compound

By orthology

Species	Potential target	Known druggable target/s	Ortholog Group
Echinococcus granulosus	sterol O acyltransferase 1	Get druggable targets OG5_133487	All targets in OG5_133487
Schistosoma mansoni	sterol O-acyltransferase 1	Get druggable targets OG5_133487	All targets in OG5_133487
Loa Loa (eye worm)	hypothetical protein	Get druggable targets OG5_133487	All targets in OG5_133487
Echinococcus multilocularis	sterol O acyltransferase 1	Get druggable targets OG5_133487	All targets in OG5_133487
Schistosoma japonicum	ko:K00637 sterol O-acyltransferase [EC2.3.1.26], putative	Get druggable targets OG5_133487	All targets in OG5_133487
Loa Loa (eye worm)	hypothetical protein	Get druggable targets OG5_133487	All targets in OG5_133487

By sequence similarity to non orthologous known druggable targets

Species	Potential target	Known druggable target	Length	Alignment span	Identity
Neospora caninum	sterol O-acyltransferase, putative	Acyl-CoA:cholesterol acyltransferase	305 aa	258 aa	20.2 %
Dictyostelium discoideum	diacylglycerol O-acyltransferase 1	Acyl-CoA:cholesterol acyltransferase	305 aa	278 aa	21.9 %

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Brugia malayi	mbt repeat family protein	0.0052	0.0016	0.0016
Trichomonas vaginalis	conserved hypothetical protein	0.0044	0.0002	0.0112
Loa Loa (eye worm)	cytochrome P450 family protein	0.031	0.0446	0.0446
Mycobacterium leprae	Conserved hypothetical protein	0.0084	0.0068	1
Trichomonas vaginalis	conserved hypothetical protein	0.0044	0.0002	0.0112
Toxoplasma gondii	PHD-finger domain-containing protein	0.0066	0.0038	0.0136
Echinococcus granulosus	cytochrome P450 2K1	0.0084	0.0068	0.0066
Brugia malayi	Cytochrome P450 family protein	0.0118	0.0126	0.0126
Trichomonas vaginalis	CMGC family protein kinase	0.014	0.0162	1
Brugia malayi	Heterochromatin protein 1	0.0077	0.0056	0.0056
Plasmodium vivax	hypothetical protein, conserved	0.0066	0.0038	1
Onchocerca volvulus	Heterochromatin protein 1 homolog	0.0046	0.0005	0.0102
Brugia malayi	MAP kinase sur-1	0.014	0.0162	0.0162
Trypanosoma cruzi	mitogen activated protein kinase 4, putative	0.014	0.0162	0.0095
Brugia malayi	Bromodomain containing protein	0.0066	0.0038	0.0038
Mycobacterium leprae	putative cytochrome p450	0.0084	0.0068	1
Trichomonas vaginalis	alpha-L-fucosidase, putative	0.0044	0.0002	0.0112
Loa Loa (eye worm)	CMGC/MAPK/JNK protein kinase	0.048	0.0731	0.0731
Trichomonas vaginalis	chromobox protein, putative	0.0046	0.0005	0.0336
Schistosoma mansoni	bromodomain-containing nuclear protein 1 brd1	0.0066	0.0038	0.0225
Loa Loa (eye worm)	hypothetical protein	0.1625	0.2642	0.2642
Mycobacterium tuberculosis	Probable cytochrome P450 140 Cyp140	0.0084	0.0068	1
Echinococcus multilocularis	geminin	0.0195	0.0254	0.0252
Echinococcus granulosus	peregrin	0.0066	0.0038	0.0036
Trichomonas vaginalis	conserved hypothetical protein	0.0044	0.0002	0.0112
Schistosoma mansoni	hypothetical protein	0.0195	0.0254	0.1574
Mycobacterium tuberculosis	Possible cytochrome P450 126 Cyp126	0.0084	0.0068	1
Loa Loa (eye worm)	TK/FAK protein kinase	0.1015	0.1624	0.1624
Echinococcus multilocularis	mitogen activated protein kinase 14	0.6031	1	1
Mycobacterium tuberculosis	Probable cytochrome P450 128 Cyp128	0.0084	0.0068	1
Echinococcus granulosus	endonuclease exonuclease phosphatase	0.0207	0.0274	0.0272
Trichomonas vaginalis	CMGC family protein kinase	0.014	0.0162	1
Leishmania major	mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440	0.014	0.0162	0.0095
Mycobacterium ulcerans	cytochrome P450 185A4 Cyp185A4	0.0118	0.0126	1
Echinococcus granulosus	discoidin domain receptor	0.0352	0.0515	0.0514
Echinococcus granulosus	suppression of tumorigenicity 18 protein	0.006	0.0028	0.0026
Schistosoma mansoni	cytochrome P450	0.0084	0.0068	0.0415
Toxoplasma gondii	PHD-finger domain-containing protein	0.0066	0.0038	0.0136
Plasmodium falciparum	phd finger protein, putative	0.0066	0.0038	1
Trichomonas vaginalis	hypothetical protein	0.0044	0.0002	0.0112
Echinococcus multilocularis	mitogen activated protein kinase 3	0.014	0.0162	0.016
Loa Loa (eye worm)	hypothetical protein	0.0264	0.0369	0.0369
Mycobacterium tuberculosis	Probable cytochrome P450 123 Cyp123	0.0084	0.0068	1
Loa Loa (eye worm)	cytochrome P450 family protein	0.0118	0.0126	0.0126
Brugia malayi	PHD-finger family protein	0.0066	0.0038	0.0038
Mycobacterium tuberculosis	Probable cytochrome P450 141 Cyp141	0.0084	0.0068	1
Echinococcus granulosus	polycomb protein SCMH1	0.0052	0.0016	0.0014
Mycobacterium tuberculosis	Probable cytochrome P450 139 Cyp139	0.0084	0.0068	1
Echinococcus granulosus	chromobox protein 1	0.0077	0.0056	0.0054
Loa Loa (eye worm)	CMGC/MAPK/P38 protein kinase	0.6031	1	1
Brugia malayi	C2-HC type zinc finger protein C.e-MyT1	0.006	0.0028	0.0028
Schistosoma mansoni	jumonji/arid domain-containing protein	0.0079	0.0061	0.0369
Mycobacterium tuberculosis	Probable cytochrome P450 137 Cyp137	0.0084	0.0068	1
Trichomonas vaginalis	conserved hypothetical protein	0.0044	0.0002	0.0112
Schistosoma mansoni	jumonji domain containing protein	0.0171	0.0213	0.1321
Leishmania major	cytochrome p450-like protein	0.0118	0.0126	0.0058
Brugia malayi	Cytochrome P450 family protein	0.0118	0.0126	0.0126
Echinococcus granulosus	PHD finger protein rhinoceros	0.0066	0.0038	0.0036
Echinococcus multilocularis	c Jun NH2 terminal kinase	0.048	0.0731	0.0729
Echinococcus multilocularis	SAM and MBT domain containing protein	0.0052	0.0016	0.0014
Echinococcus multilocularis	histone acetyltransferase MYST2	0.006	0.0028	0.0026
Echinococcus multilocularis	PHD finger protein rhinoceros	0.0066	0.0038	0.0036
Schistosoma mansoni	hypothetical protein	0.0084	0.0068	0.0415
Brugia malayi	Cytochrome P450 family protein	0.031	0.0446	0.0446
Brugia malayi	jmjC domain containing protein	0.0079	0.0061	0.0061
Echinococcus multilocularis		0.0084	0.0068	0.0066
Loa Loa (eye worm)	CYP4Cod1	0.0118	0.0126	0.0126
Echinococcus granulosus	SAM and MBT domain containing protein	0.0052	0.0016	0.0014
Brugia malayi	Cytochrome P450 family protein	0.0084	0.0068	0.0068
Schistosoma mansoni	sterol O-acyltransferase 1	0.0264	0.0369	0.2292
Trichomonas vaginalis	beta-hexosaminidase B, putative	0.0044	0.0002	0.0112
Trichomonas vaginalis	conserved hypothetical protein	0.0044	0.0002	0.0112
Toxoplasma gondii	hypothetical protein	0.1625	0.2642	1
Trichomonas vaginalis	chromobox protein, putative	0.0077	0.0056	0.3469
Schistosoma mansoni	serine/threonine protein kinase	0.048	0.0731	0.4549
Loa Loa (eye worm)	hypothetical protein	0.1625	0.2642	0.2642
Mycobacterium tuberculosis	Probable cytochrome P450 144 Cyp144	0.0084	0.0068	1
Echinococcus multilocularis	chromobox protein 1	0.0077	0.0056	0.0054
Mycobacterium tuberculosis	Probable cytochrome P450 130 Cyp130	0.0084	0.0068	1
Mycobacterium tuberculosis	Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM)	0.0084	0.0068	1
Loa Loa (eye worm)	hypothetical protein	0.0352	0.0515	0.0515
Echinococcus granulosus	mitogen activated protein kinase 3	0.014	0.0162	0.016
Trichomonas vaginalis	conserved hypothetical protein	0.0044	0.0002	0.0112
Trypanosoma cruzi	cytochrome P450, putative	0.0118	0.0126	0.0058
Trichomonas vaginalis	conserved hypothetical protein	0.0044	0.0002	0.0112
Brugia malayi	cytochrome P450	0.0084	0.0068	0.0068
Loa Loa (eye worm)	hypothetical protein	0.1625	0.2642	0.2642
Echinococcus granulosus	jumonji domain containing protein	0.0091	0.0081	0.0079
Trichomonas vaginalis	alpha-L-fucosidase, putative	0.0044	0.0002	0.0112
Loa Loa (eye worm)	PHD-finger family protein	0.0066	0.0038	0.0038
Mycobacterium tuberculosis	Probable cytochrome P450 138 Cyp138	0.0084	0.0068	1
Trichomonas vaginalis	conserved hypothetical protein	0.0044	0.0002	0.0112
Loa Loa (eye worm)	hypothetical protein	0.0066	0.0038	0.0038
Trichomonas vaginalis	conserved hypothetical protein	0.0044	0.0002	0.0112
Loa Loa (eye worm)	hypothetical protein	0.0044	0.0002	0.0002
Giardia lamblia	Kinase, CMGC MAPK	0.014	0.0162	1
Trichomonas vaginalis	CMGC family protein kinase	0.014	0.0162	1
Trichomonas vaginalis	conserved hypothetical protein	0.0044	0.0002	0.0112
Trypanosoma cruzi	mitogen-activated protein kinase 11, putative	0.014	0.0162	0.0095
Mycobacterium tuberculosis	Probable cytochrome P450 125 Cyp125	0.0084	0.0068	1
Loa Loa (eye worm)	hypothetical protein	0.0317	0.0458	0.0458
Echinococcus multilocularis	Transcription factor, JmjC domain containing protein	0.0215	0.0287	0.0285
Leishmania major	mitogen-activated protein kinase 3, putative,map kinase 3, putative	0.6031	1	1
Echinococcus multilocularis	jumonji domain containing protein	0.0091	0.0081	0.0079
Mycobacterium tuberculosis	Cytochrome P450 121 Cyp121	0.0084	0.0068	1
Echinococcus multilocularis	microtubule associated protein 2	0.0759	0.1196	0.1194
Loa Loa (eye worm)	TK/DDR protein kinase	0.0317	0.0458	0.0458
Trypanosoma cruzi	mitogen-activated protein kinase 3, putative	0.6031	1	1
Brugia malayi	jmjC domain containing protein	0.0215	0.0287	0.0287
Trypanosoma cruzi	mitogen-activated protein kinase 11, putative	0.014	0.0162	0.0095
Onchocerca volvulus		0.0052	0.0016	0.0299
Loa Loa (eye worm)	hypothetical protein	0.0113	0.0116	0.0116
Loa Loa (eye worm)	mbt repeat family protein	0.0052	0.0016	0.0016
Brugia malayi	Protein kinase domain containing protein	0.0361	0.0532	0.0532
Echinococcus granulosus	histone acetyltransferase MYST2	0.006	0.0028	0.0026
Mycobacterium tuberculosis	Possible cytochrome P450 135B1 Cyp135B1	0.0084	0.0068	1
Echinococcus multilocularis	mitogen activated protein kinase 11	0.6031	1	1
Trypanosoma brucei	mitogen-activated protein kinase 3, putative	0.6031	1	1
Leishmania major	mitogen activated protein kinase, putative,map kinase, putative	0.014	0.0162	0.0095
Schistosoma mansoni	sex comb on midleg homolog	0.0052	0.0016	0.0088
Echinococcus granulosus	mitogen activated protein kinase 14	0.6031	1	1
Loa Loa (eye worm)	inward rectifying k channel family protein 1	0.1625	0.2642	0.2642
Schistosoma mansoni	scm-relatedprotein containing 4 mbt domains (sfmbt)	0.0052	0.0016	0.0088
Schistosoma mansoni	chromobox protein	0.0077	0.0056	0.034
Loa Loa (eye worm)	jmjC domain-containing protein	0.0079	0.0061	0.0061
Loa Loa (eye worm)	cytochrome P450	0.0084	0.0068	0.0068
Echinococcus granulosus	mitogen activated protein kinase 11	0.6031	1	1
Mycobacterium tuberculosis	Possible cytochrome P450 135A1 Cyp135A1	0.0084	0.0068	1
Loa Loa (eye worm)	hypothetical protein	0.0044	0.0002	0.0002
Schistosoma mansoni	sex comb on midleg homolog	0.0052	0.0016	0.0088
Echinococcus multilocularis	polycomb protein SCMH1	0.0052	0.0016	0.0014
Schistosoma mansoni	hypothetical protein	0.0195	0.0254	0.1574
Trichomonas vaginalis	conserved hypothetical protein	0.0044	0.0002	0.0112
Echinococcus granulosus	c-Jun N-terminal kinases	0.048	0.0731	0.0729
Loa Loa (eye worm)	heterochromatin protein 1	0.0077	0.0056	0.0056
Mycobacterium tuberculosis	Probable cytochrome P450 143 Cyp143	0.0084	0.0068	1
Trichomonas vaginalis	chromobox protein, putative	0.0046	0.0005	0.0336
Onchocerca volvulus		0.0044	0.0002	0.0034
Trichomonas vaginalis	chromobox protein, putative	0.0077	0.0056	0.3469
Echinococcus granulosus	geminin	0.0195	0.0254	0.0252
Loa Loa (eye worm)	cytochrome P450 family protein	0.0118	0.0126	0.0126
Echinococcus multilocularis	protein tyrosine kinase	0.1003	0.1604	0.1602
Loa Loa (eye worm)	MBCTL1	0.006	0.0028	0.0028
Mycobacterium tuberculosis	Probable cytochrome P450 132 Cyp132	0.0084	0.0068	1
Brugia malayi	mbt repeat family protein	0.0052	0.0016	0.0016
Brugia malayi	Protein kinase domain containing protein	0.1015	0.1624	0.1624
Echinococcus multilocularis	peregrin	0.0066	0.0038	0.0036
Trypanosoma cruzi	mitogen-activated protein kinase 3, putative	0.6031	1	1
Brugia malayi	Stress-activated protein kinase jnk-1	0.048	0.0731	0.0731
Echinococcus multilocularis	endonuclease exonuclease phosphatase	0.0207	0.0274	0.0272
Schistosoma mansoni	microtubule-associated protein tau	0.0759	0.1196	0.7453
Trypanosoma brucei	mitogen activated protein kinase 4, putative	0.014	0.0162	0.0095
Echinococcus multilocularis	suppression of tumorigenicity 18 protein	0.006	0.0028	0.0026
Echinococcus granulosus	protein tyrosine kinase	0.1003	0.1604	0.1602
Echinococcus granulosus	Transcription factor JmjC domain containing protein	0.0215	0.0287	0.0285
Loa Loa (eye worm)	hypothetical protein	0.0052	0.0016	0.0016
Toxoplasma gondii	CMGC kinase, MAPK family (ERK) MAPK-1	0.014	0.0162	0.0607
Schistosoma mansoni	serine/threonine protein kinase	0.014	0.0162	0.1001
Echinococcus multilocularis	sterol O acyltransferase 1	0.0264	0.0369	0.0367
Echinococcus granulosus	microtubule associated protein 2	0.0759	0.1196	0.1194
Echinococcus granulosus	sterol O acyltransferase 1	0.0264	0.0369	0.0367
Schistosoma mansoni	tyrosine kinase	0.1003	0.1604	1
Onchocerca volvulus	Alhambra homolog	0.0066	0.0038	0.0712
Trichomonas vaginalis	CMGC family protein kinase	0.014	0.0162	1
Echinococcus multilocularis	mitogen activated protein kinase 11	0.6031	1	1
Loa Loa (eye worm)	hypothetical protein	0.006	0.0028	0.0028
Schistosoma mansoni	myelin transcription factor 1 myt1	0.006	0.0028	0.0163
Trichomonas vaginalis	conserved hypothetical protein	0.0044	0.0002	0.0112
Schistosoma mansoni	hypothetical protein	0.0066	0.0038	0.0225
Echinococcus multilocularis	chromobox protein 1	0.0077	0.0056	0.0054
Schistosoma mansoni	chromobox protein	0.0077	0.0056	0.034
Echinococcus multilocularis	mitogen activated protein kinase 14	0.6031	1	1
Echinococcus granulosus	mitogen activated protein kinase	0.014	0.0162	0.016
Trypanosoma cruzi	mitogen activated protein kinase 2, putative	0.014	0.0162	0.0095
Trypanosoma brucei	protein kinase, putative	0.014	0.0162	0.0095
Schistosoma mansoni	jumonji/arid domain-containing protein	0.0079	0.0061	0.0369
Echinococcus multilocularis	mitogen activated protein kinase	0.014	0.0162	0.016
Echinococcus granulosus	chromobox protein 1	0.0077	0.0056	0.0054
Trypanosoma brucei	cytochrome P450, putative	0.0118	0.0126	0.0058
Loa Loa (eye worm)	CMGC/MAPK/ERK1 protein kinase	0.014	0.0162	0.0162
Onchocerca volvulus	Polycomb protein Sfmbt homolog	0.0052	0.0016	0.0299
Echinococcus multilocularis	lysine specific demethylase 5A	0.0079	0.0061	0.0059
Schistosoma mansoni	hypothetical protein	0.0319	0.0461	0.2866
Mycobacterium tuberculosis	Probable cytochrome P450 124 Cyp124	0.0084	0.0068	1
Echinococcus granulosus	lysine specific demethylase 5A	0.0079	0.0061	0.0059
Onchocerca volvulus		0.0361	0.0532	1
Mycobacterium tuberculosis	Probable cytochrome P450 136 Cyp136	0.0084	0.0068	1
Trichomonas vaginalis	conserved hypothetical protein	0.0044	0.0002	0.0112
Trypanosoma cruzi	cytochrome P450, putative	0.0118	0.0126	0.0058
Mycobacterium tuberculosis	Probable cytochrome P450 monooxygenase 142 Cyp142	0.0084	0.0068	1
Toxoplasma gondii	cytochrome p450 superfamily protein	0.0084	0.0068	0.0252
Trichomonas vaginalis	conserved hypothetical protein	0.0044	0.0002	0.0112
Trichomonas vaginalis	conserved hypothetical protein	0.0044	0.0002	0.0112
Loa Loa (eye worm)	jmjC domain-containing protein	0.0136	0.0155	0.0155
Loa Loa (eye worm)	hypothetical protein	0.0238	0.0326	0.0326

Activities

Activity type	Activity value	Assay description	Source	Reference
Change (functional)	= -29 %	In vivo percent change in the total cholesterol after consumption of a single high fat, high cholesterol meal by rats	ChEMBL.	No reference
IC50 (binding)	= 0.071 uM	In vitro inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase in intestinal microsomes isolated from cholesterol fed rabbits (IAI).	ChEMBL.	No reference
IC50 (binding)	= 0.071 uM	In vitro inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase in intestinal microsomes isolated from cholesterol fed rabbits (IAI).	ChEMBL.	No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL159285
PubChem: 9888659

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 277394