Detailed information for compound 40038

Basic information

Technical information
  • TDR Targets ID: 40038
  • Name: 9-(cyclohexylmethyl)-6-(furan-2-yl)purine
  • MW: 282.34 | Formula: C16H18N4O
  • H donors: 0 H acceptors: 3 LogP: 3.12 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: C1CCC(CC1)Cn1cnc2c1ncnc2c1ccco1
  • InChi: 1S/C16H18N4O/c1-2-5-12(6-3-1)9-20-11-19-15-14(13-7-4-8-21-13)17-10-18-16(15)20/h4,7-8,10-12H,1-3,5-6,9H2
  • InChiKey: AVOJBTZQXLDCSM-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 9-(cyclohexylmethyl)-6-(2-furyl)purine
  • 9-(cyclohexylmethyl)-6-furan-2-ylpurine
  • 9-(cyclohexylmethyl)-6-furan-2-yl-purine
  • AIDS103556
  • 9H-Purine, 9-(cyclohexylmethyl)-6-(2-furanyl)-
  • AIDS-103556

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0014 0.0041 0.0047
Onchocerca volvulus 0.0014 0.0041 0.0134
Plasmodium falciparum threonine--tRNA ligase 0.0012 0.002 0.0018
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0037 0.0269 0.0321
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.2663 0.6567
Plasmodium falciparum calcium-dependent protein kinase 3 0.0064 0.0528 0.0614
Echinococcus multilocularis calcium dependent protein kinase 0.006 0.049 0.0584
Trypanosoma cruzi sugar transporter, putative 0.006 0.0489 0.4068
Loa Loa (eye worm) hypothetical protein 0.0014 0.0041 0.009
Entamoeba histolytica protein kinase, putative 0.0064 0.0528 0.1605
Loa Loa (eye worm) hypothetical protein 0.0052 0.0411 0.0934
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0293 0.246
Plasmodium vivax DNA polymerase delta catalytic subunit, putative 0.0018 0.0084 0.0075
Echinococcus granulosus calcium dependent protein kinase 0.006 0.049 0.0584
Echinococcus granulosus rhodopsin orphan GPCR 0.0052 0.0411 0.049
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0014 0.0041 0.004
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0025 0.0151 0.1271
Echinococcus multilocularis neuropeptide s receptor 0.0052 0.0411 0.049
Onchocerca volvulus 0.0052 0.0411 0.1389
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0064 0.0528 0.063
Brugia malayi beta-lactamase 0.0035 0.0245 0.0603
Loa Loa (eye worm) hypothetical protein 0.0189 0.1751 0.3987
Loa Loa (eye worm) DNA polymerase epsilon catalytic subunit 0.001 0.0005 0.0008
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0043 0.0321 0.2654
Trichomonas vaginalis DNA helicase recq, putative 0.0063 0.0521 0.1274
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0014 0.0041 0.0098
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0411 0.041
Loa Loa (eye worm) hypothetical protein 0.006 0.0489 0.1111
Trypanosoma brucei glucose transporter 2A 0.0132 0.1192 1
Loa Loa (eye worm) hypothetical protein 0.006 0.0489 0.1111
Schistosoma mansoni hypothetical protein 0.0015 0.0055 0.0053
Leishmania major DNA polymerase delta catalytic subunit, putative 0.0018 0.0084 0.0651
Brugia malayi Flap endonuclease-1 0.0025 0.0151 0.0371
Mycobacterium ulcerans hypothetical protein 0.0035 0.0245 0.1915
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0019 0.0091 0.0711
Brugia malayi lysyl-tRNA synthetase 0.0046 0.0359 0.0884
Trichomonas vaginalis sugar transporter, putative 0.0132 0.1192 0.2933
Trichomonas vaginalis DNA polymerase alpha catalytic subunit, putative 0.0018 0.0084 0.0196
Trichomonas vaginalis sugar transporter, putative 0.006 0.0489 0.1196
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0052 0.0411 0.041
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0062 0.0515 0.1565
Trichomonas vaginalis sugar transporter, putative 0.006 0.0489 0.1196
Mycobacterium ulcerans lipase LipD 0.0035 0.0245 0.1915
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0293 0.246
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0062 0.0515 0.0615
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0064 0.0528 0.063
Loa Loa (eye worm) hypothetical protein 0.0052 0.0411 0.0934
Toxoplasma gondii ABC1 family protein 0.0035 0.0245 0.0423
Schistosoma mansoni glucose transporter 0.006 0.0489 0.0488
Mycobacterium leprae Probable lipase LipE 0.0035 0.0245 0.1915
Chlamydia trachomatis lysine--tRNA ligase 0.0046 0.0359 1
Brugia malayi Melatonin receptor type 1A 0.0052 0.0411 0.1012
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0014 0.0042 0.0049
Brugia malayi G protein-coupled receptor 0.0052 0.0411 0.1012
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0014 0.0041 0.0098
Echinococcus multilocularis dro:myosuppressin receptor 0.0052 0.0411 0.049
Echinococcus granulosus glycine receptor subunit beta 0.0014 0.0041 0.0047
Trypanosoma brucei sugar transporter, putative 0.006 0.0489 0.4102
Loa Loa (eye worm) hypothetical protein 0.0052 0.0411 0.0934
Loa Loa (eye worm) hypothetical protein 0.006 0.0489 0.1111
Brugia malayi hypothetical protein 0.0052 0.0411 0.1012
Loa Loa (eye worm) LGC-31 protein 0.0014 0.0041 0.009
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0064 0.0528 0.0597
Loa Loa (eye worm) sugar transporter 0.006 0.0489 0.1111
Echinococcus multilocularis glycine receptor subunit beta 0.0014 0.0041 0.0047
Toxoplasma gondii glycyl-tRNA synthetase 0.0012 0.002 0.0024
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0019 0.0091 0.0711
Onchocerca volvulus 0.0052 0.0411 0.1389
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0064 0.0528 0.0597
Brugia malayi beta-lactamase family protein 0.0035 0.0245 0.0603
Brugia malayi hypothetical protein 0.0052 0.0411 0.1012
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.1637 0.4034
Trypanosoma brucei threonyl-tRNA synthetase, putative 0.0012 0.002 0.0169
Schistosoma mansoni DNA polymerase alpha catalytic subunit 0.0018 0.0084 0.0083
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0091 0.0149
Onchocerca volvulus 0.0035 0.0245 0.0828
Giardia lamblia Flap structure-specific endonuclease 0.0025 0.0151 0.0415
Loa Loa (eye worm) hypothetical protein 0.0052 0.0411 0.0934
Loa Loa (eye worm) major facilitator superfamily transporter 0.006 0.0489 0.1111
Echinococcus multilocularis solute carrier family 22 0.006 0.0489 0.0583
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0425 0.4052 0.4842
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0293 0.2299
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0062 0.0515 0.0514
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0052 0.0411 0.041
Echinococcus granulosus solute carrier family 22 0.006 0.0489 0.0583
Schistosoma mansoni amine GPCR 0.0052 0.0411 0.041
Plasmodium vivax DNA polymerase alpha, putative 0.0018 0.0084 0.0075
Loa Loa (eye worm) sugar transporter 0.0425 0.4052 0.9232
Brugia malayi GnHR receptor homolog 0.0052 0.0411 0.1012
Onchocerca volvulus 0.006 0.0489 0.1652
Giardia lamblia Sugar-proton symporter 0.006 0.0489 0.1481
Brugia malayi ORL1-like opioid receptor 0.0052 0.0411 0.1012
Plasmodium falciparum protein kinase 6 0.0883 0.8531 1
Onchocerca volvulus DNA polymerase epsilon catalytic subunit A homolog 0.0018 0.0084 0.028
Trichomonas vaginalis DNA helicase recq1, putative 0.0063 0.0521 0.1274
Brugia malayi neuropeptide F receptor 0.0052 0.0411 0.1012
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0046 0.0359 0.283
Plasmodium vivax hexose transporter 0.0425 0.4052 0.4738
Onchocerca volvulus 0.006 0.0489 0.1652
Brugia malayi ImpB/MucB/SamB family protein 0.0014 0.0042 0.0102
Echinococcus granulosus rhodopsin orphan GPCR 0.0052 0.0411 0.049
Loa Loa (eye worm) hypothetical protein 0.006 0.0489 0.1111
Trichomonas vaginalis sugar transporter, putative 0.006 0.0489 0.1196
Onchocerca volvulus 0.0052 0.0411 0.1389
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0037 0.0269 0.0321
Onchocerca volvulus 0.006 0.0489 0.1652
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0052 0.0411 0.0934
Trichomonas vaginalis DNA helicase recq, putative 0.0043 0.0321 0.0782
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0014 0.0041 0.0098
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0014 0.0041 0.004
Toxoplasma gondii threonyl-tRNA synthetase family protein 0.0012 0.002 0.0024
Loa Loa (eye worm) latrophilin receptor protein 2 0.0015 0.0055 0.0122
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0073 0.0617 0.5173
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0014 0.0041 0.0047
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0052 0.0411 0.1389
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0052 0.0411 0.041
Schistosoma mansoni nAChR subunit 0.0014 0.0041 0.004
Trypanosoma brucei telomerase reverse transcriptase 0.0085 0.0738 0.6192
Echinococcus multilocularis g protein coupled receptor 0.0052 0.0411 0.049
Schistosoma mansoni hypothetical protein 0.0341 0.3236 0.3235
Plasmodium falciparum lysine--tRNA ligase 0.0046 0.0359 0.0416
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0245 0.0595
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.027 0.2545 0.5797
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0014 0.0041 0.0098
Plasmodium falciparum calcium-dependent protein kinase 5 0.0064 0.0528 0.0614
Schistosoma mansoni nAChR subunit 0.0014 0.0041 0.004
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.002 0.0105 0.0472
Echinococcus multilocularis g protein coupled receptor 0.0052 0.0411 0.049
Plasmodium falciparum calcium-dependent protein kinase 1 0.0064 0.0528 0.0614
Loa Loa (eye worm) hypothetical protein 0.0052 0.0411 0.0934
Loa Loa (eye worm) ACC-1 protein 0.0014 0.0041 0.009
Loa Loa (eye worm) hypothetical protein 0.0413 0.3936 0.8968
Brugia malayi Major Facilitator Superfamily protein 0.006 0.0489 0.1204
Echinococcus multilocularis rhodopsin orphan GPCR 0.0052 0.0411 0.049
Loa Loa (eye worm) hypothetical protein 0.0052 0.0411 0.0934
Loa Loa (eye worm) hypothetical protein 0.0037 0.0269 0.0611
Loa Loa (eye worm) glycyl-tRNA synthetase 0.0012 0.002 0.0043
Echinococcus granulosus bloom syndrome protein 0.0063 0.0521 0.0621
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0052 0.0411 0.041
Loa Loa (eye worm) hypothetical protein 0.0052 0.0411 0.0934
Onchocerca volvulus Glucosylceramidase homolog 0.0177 0.1637 0.5544
Schistosoma mansoni DNA polymerase epsilon catalytic subunit 0.0018 0.0084 0.0083
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0489 0.1196
Schistosoma mansoni opsin-like receptor 0.0052 0.0411 0.041
Echinococcus granulosus glycine receptor subunit alpha 1 0.0014 0.0041 0.0047
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0064 0.0528 0.063
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.004 0.0293 0.0713
Trypanosoma cruzi hexose transporter, putative 0.006 0.0489 0.4068
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0014 0.0041 0.0047
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0052 0.0411 0.049
Trypanosoma brucei DNA polymerase eta, putative 0.0014 0.0042 0.0356
Giardia lamblia Fructose-bisphosphate aldolase 0.0282 0.2663 0.835
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0867 0.8367 1
Loa Loa (eye worm) melatonin receptor type 1A 0.0052 0.0411 0.0934
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0245 0.1153
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0037 0.0269 0.0662
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0293 0.246
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0025 0.0151 0.1221
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0411 0.041
Loa Loa (eye worm) hypothetical protein 0.0052 0.0411 0.0934
Onchocerca volvulus DNA polymerase delta catalytic subunit homolog 0.0018 0.0084 0.028
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.1637 0.4034
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0245 0.0292
Trichomonas vaginalis sugar transporter, putative 0.006 0.0489 0.1196
Brugia malayi putative neuropeptide receptor NPR1 0.0052 0.0411 0.1012
Trichomonas vaginalis sugar transporter, putative 0.006 0.0489 0.1196
Echinococcus multilocularis neuropeptide Y receptor 0.0052 0.0411 0.049
Schistosoma mansoni myosin xvIII 0.0052 0.0411 0.041
Loa Loa (eye worm) hypothetical protein 0.0052 0.0411 0.0934
Echinococcus multilocularis rhodopsin orphan GPCR 0.0052 0.0411 0.049
Plasmodium vivax calcium-dependent protein kinase, putative 0.0064 0.0528 0.0597
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0008
Trichomonas vaginalis esterase, putative 0.0035 0.0245 0.0595
Onchocerca volvulus Neuropeptide F receptor homolog 0.0052 0.0411 0.1389
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0037 0.0269 0.0465
Brugia malayi hypothetical protein 0.0052 0.0411 0.1012
Loa Loa (eye worm) hypothetical protein 0.0052 0.0411 0.0934
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0138 0.1253 0.6022
Trypanosoma brucei DNA polymerase IV, putative 0.0033 0.0231 0.1938
Leishmania major DNA polymerase I alpha catalytic subunit, putative 0.0018 0.0084 0.0651
Loa Loa (eye worm) hypothetical protein 0.0052 0.0411 0.0934
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0052 0.0411 0.0934
Echinococcus granulosus flap endonuclease 1 0.0025 0.0151 0.018
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0046 0.0359 0.3016
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0245 0.0595
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0052 0.0411 0.049
Onchocerca volvulus 0.0052 0.0411 0.1389
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.1637 0.4034
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0015 0.0055 0.0064
Echinococcus granulosus hypothetical protein 0.0052 0.0411 0.049
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0245 0.1153
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0014 0.0041 0.0098
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0293 0.246
Mycobacterium tuberculosis Conserved protein 0.0035 0.0245 0.1153
Brugia malayi hypothetical protein 0.0052 0.0411 0.1012
Onchocerca volvulus 0.006 0.0489 0.1652
Trichomonas vaginalis sugar transporter, putative 0.006 0.0489 0.1196
Onchocerca volvulus 0.0014 0.0041 0.0134
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0073 0.0617 0.5145
Brugia malayi hypothetical protein 0.0052 0.0411 0.1012
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0052 0.0411 0.041
Echinococcus multilocularis solute carrier family 22 0.006 0.0489 0.0583
Loa Loa (eye worm) hypothetical protein 0.0052 0.0411 0.0934
Plasmodium vivax sugar transporter, putative 0.006 0.0489 0.0551
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0046 0.0359 0.283
Echinococcus granulosus allatostatin A receptor 0.0052 0.0411 0.049
Schistosoma mansoni hypothetical protein 0.0052 0.0411 0.041
Echinococcus granulosus rhodopsin orphan GPCR 0.0052 0.0411 0.049
Echinococcus multilocularis DNA polymerase alpha catalytic subunit 0.0018 0.0084 0.0099
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0062 0.0515 0.127
Trypanosoma brucei glucose transporter, putative 0.0132 0.1192 1
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0014 0.0041 0.0098
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.006 0.0489 1
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0783 0.7555 0.9029
Loa Loa (eye worm) hypothetical protein 0.0014 0.0041 0.009
Echinococcus granulosus glycine receptor subunit alpha 1 0.0014 0.0041 0.0047
Schistosoma mansoni glucose transport protein 0.0425 0.4052 0.4051
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0064 0.0528 0.063
Echinococcus multilocularis DNA polymerase zeta catalytic subunit 0.0018 0.0084 0.0099
Loa Loa (eye worm) hypothetical protein 0.0046 0.0359 0.0816
Trypanosoma brucei unspecified product 0.0033 0.0231 0.1938
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0052 0.0411 0.041
Brugia malayi hypothetical protein 0.0052 0.0411 0.1012
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0052 0.0411 0.049
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0411 0.041
Brugia malayi Cation transporter family protein 0.0014 0.0041 0.0098
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0046 0.0359 0.2975
Echinococcus granulosus g protein coupled receptor 0.0052 0.0411 0.049
Schistosoma mansoni neuropeptide F-like receptor 0.0052 0.0411 0.041
Plasmodium vivax lysine--tRNA ligase, putative 0.0046 0.0359 0.0399
Plasmodium falciparum mitogen-activated protein kinase 2 0.0336 0.319 0.3735
Mycobacterium leprae Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase) (ThrRS) (Threonine-tRNA ligase) 0.0012 0.002 0.0107
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0014 0.0041 0.0047
Echinococcus granulosus rhodopsin orphan GPCR 0.0052 0.0411 0.049
Echinococcus multilocularis rhodopsin orphan GPCR 0.0052 0.0411 0.049
Echinococcus granulosus neuropeptide s receptor 0.0052 0.0411 0.049
Echinococcus granulosus g protein coupled receptor 0.0052 0.0411 0.049
Brugia malayi DNA polymerase delta catalytic subunit 0.0018 0.0084 0.0204
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0411 0.041
Schistosoma mansoni blooms syndrome DNA helicase 0.0019 0.0091 0.009
Trichomonas vaginalis conserved hypothetical protein 0.0132 0.1192 0.2933
Schistosoma mansoni biogenic amine receptor 0.0052 0.0411 0.041
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0025 0.0151 0.1221
Onchocerca volvulus 0.006 0.0489 0.1652
Schistosoma mansoni sugar transporter 0.006 0.0489 0.0488
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0064 0.0528 0.0925
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0064 0.0528 0.1201
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0014 0.0041 0.0047
Echinococcus multilocularis neuropeptide receptor A26 0.0052 0.0411 0.049
Brugia malayi Dopamine receptor protein 1 0.0052 0.0411 0.1012
Loa Loa (eye worm) hypothetical protein 0.0062 0.0515 0.1172
Brugia malayi Major Facilitator Superfamily protein 0.006 0.0489 0.1204
Leishmania major glucose transporter, lmgt2 0.0132 0.1192 1
Brugia malayi DNA polymerase alpha catalytic subunit 0.0018 0.0084 0.0204
Trypanosoma brucei glycyl-tRNA synthetase, putative 0.0012 0.002 0.0169
Giardia lamblia DNA polymerase delta, catalytic subunit 0.0018 0.0084 0.0202
Brugia malayi Calcitonin receptor-like protein seb-1 0.0048 0.0376 0.0925
Echinococcus granulosus rhodopsin orphan GPCR 0.0052 0.0411 0.049
Loa Loa (eye worm) hypothetical protein 0.001 0.0005 0.0008
Echinococcus multilocularis G-protein coupled receptor, putative 0.0052 0.0411 0.049
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0007 0.0005
Loa Loa (eye worm) hypothetical protein 0.0014 0.0041 0.009
Echinococcus granulosus dna polymerase kappa 0.004 0.0293 0.0349
Trypanosoma brucei glucose transporter, putative 0.0132 0.1192 1
Schistosoma mansoni biogenic amine receptor 0.0052 0.0411 0.041
Echinococcus multilocularis flap endonuclease 1 0.0025 0.0151 0.018
Echinococcus multilocularis glycine receptor subunit beta 0.0014 0.0041 0.0047
Schistosoma mansoni protein kinase 0.0064 0.0528 0.0527
Trypanosoma cruzi hexose transporter, putative 0.0132 0.1192 1
Plasmodium vivax DNA polymerase epsilon, catalytic subunit a, putative 0.0018 0.0084 0.0075
Leishmania major glucose transporter/membrane transporter D2, putative 0.0132 0.1192 1
Schistosoma mansoni hypothetical protein 0.0015 0.0055 0.0053
Trypanosoma cruzi hexose transporter, putative 0.0072 0.0609 0.508
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0052 0.0411 0.049
Toxoplasma gondii RNA-directed DNA polymerase 0.0085 0.0738 0.1296
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0073 0.0617 0.5145
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0014 0.0041 0.0047
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0052 0.0411 0.049
Loa Loa (eye worm) hypothetical protein 0.0052 0.0411 0.0934
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0411 0.041
Brugia malayi larval opioid receptor 0.0052 0.0411 0.1012
Trichomonas vaginalis sugar transporter, putative 0.006 0.0489 0.1196
Brugia malayi G-protein coupled receptor 0.0052 0.0411 0.1012
Plasmodium vivax proline--tRNA ligase, putative 0.0073 0.0617 0.0701
Brugia malayi Sugar transporter family protein 0.006 0.0489 0.1204
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0489 0.1196
Trichomonas vaginalis sugar transporter, putative 0.006 0.0489 0.1196
Loa Loa (eye worm) hypothetical protein 0.006 0.0489 0.1111
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0052 0.0411 0.1012
Echinococcus multilocularis neuropeptide FF receptor 2 0.0052 0.0411 0.049
Loa Loa (eye worm) threonyl-tRNA synthetase 0.0012 0.002 0.0043
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0245 0.1153
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0043 0.0321 0.2696
Echinococcus granulosus dna polymerase epsilon catalytic subunit a 0.0018 0.0084 0.0099
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0052 0.0411 0.049
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0293 0.246
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.2663 0.6567
Brugia malayi DNA polymerase family B, exonuclease domain containing protein 0.0018 0.0084 0.0204
Loa Loa (eye worm) hypothetical protein 0.0104 0.0919 0.2092
Giardia lamblia Hexose transporter 0.006 0.0489 0.1481
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0062 0.0515 0.0514
Schistosoma mansoni biogenic amine receptor 0.0052 0.0411 0.041
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0014 0.0041 0.0047
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0336 0.319 0.5643
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0073 0.0617 0.1081
Entamoeba histolytica protein kinase, putative 0.0064 0.0528 0.1605
Toxoplasma gondii DNA polymerase family B protein 0.0018 0.0084 0.0137
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0052 0.0411 0.1012
Onchocerca volvulus 0.006 0.0489 0.1652
Trichomonas vaginalis sugar transporter, putative 0.006 0.0489 0.1196
Trichomonas vaginalis glucosylceramidase, putative 0.027 0.2545 0.6276
Entamoeba histolytica deoxycytidyl transferase, putative 0.0014 0.0042 0.007
Trichomonas vaginalis DNA polymerase II, putative 0.0018 0.0084 0.0196
Brugia malayi Serotonin receptor 0.0052 0.0411 0.1012
Loa Loa (eye worm) hypothetical protein 0.0052 0.0411 0.0934
Entamoeba histolytica hypothetical protein 0.0046 0.0359 0.1072
Trichomonas vaginalis sugar transporter, putative 0.006 0.0489 0.1196
Loa Loa (eye worm) hypothetical protein 0.0033 0.0227 0.0515
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0052 0.0411 0.049
Echinococcus granulosus solute carrier family 22 0.006 0.0489 0.0583
Plasmodium falciparum telomerase reverse transcriptase 0.0085 0.0738 0.086
Schistosoma mansoni growth hormone secretagogue receptor 0.0052 0.0411 0.041
Mycobacterium ulcerans integral membrane transport protein 0.006 0.0489 0.3869
Brugia malayi Major Facilitator Superfamily protein 0.006 0.0489 0.1204
Trichomonas vaginalis threonyl-tRNA synthetase, putative 0.0012 0.002 0.0038
Echinococcus multilocularis fmrfamide receptor 0.0052 0.0411 0.049
Brugia malayi RE15519p 0.0052 0.0411 0.1012
Brugia malayi major facilitator superfamily protein 0.006 0.0489 0.1204
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0037 0.0269 0.0321
Trichomonas vaginalis sugar transporter, putative 0.006 0.0489 0.1196
Echinococcus granulosus nAChR subunit 0.0014 0.0041 0.0047
Echinococcus granulosus rhodopsin orphan GPCR 0.0052 0.0411 0.049
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0014 0.0041 0.0047
Schistosoma mansoni opsin-like receptor 0.0052 0.0411 0.041
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0014 0.0041 0.0098
Leishmania major glucose transporter, lmgt3 0.0132 0.1192 1
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.1637 0.4034
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0245 0.0244
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0039 0.029 0.0317
Loa Loa (eye worm) hypothetical protein 0.0052 0.0411 0.0934
Loa Loa (eye worm) hypothetical protein 0.0014 0.0041 0.009
Trypanosoma cruzi hexose transporter, putative 0.0132 0.1192 1
Trichomonas vaginalis glucose transporter, putative 0.0132 0.1192 0.2933
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0052 0.0411 0.049
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0052 0.0411 0.041
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0052 0.0411 0.049
Brugia malayi Tachykinin-like peptides receptor 99D 0.0052 0.0411 0.1012
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0293 0.2417
Loa Loa (eye worm) hypothetical protein 0.0052 0.0411 0.0934
Schistosoma mansoni nAChR subunit 0.0014 0.0041 0.004
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0062 0.0515 0.127
Brugia malayi G-protein coupled receptor 0.0052 0.0411 0.1012
Loa Loa (eye worm) hypothetical protein 0.0052 0.0411 0.0934
Trichomonas vaginalis sugar transporter, putative 0.006 0.0489 0.1196
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0014 0.0041 0.009
Trichomonas vaginalis sugar transporter, putative 0.006 0.0489 0.1196
Trypanosoma cruzi DNA polymerase epsilon catalytic subunit, putative 0.0018 0.0084 0.0651
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0007 0.0005
Echinococcus granulosus g protein coupled receptor 0.0052 0.0411 0.049
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0052 0.0411 0.0934
Echinococcus granulosus neuropeptide receptor A26 0.0052 0.0411 0.049
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0039 0.0283 0.049
Giardia lamblia DINP protein human, muc B family 0.002 0.0105 0.0267
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.0085 0.0738 0.617
Trypanosoma brucei glucose transporter 1E 0.0132 0.1192 1
Schistosoma mansoni amine GPCR 0.0052 0.0411 0.041
Schistosoma mansoni glucose transport protein 0.0425 0.4052 0.4051
Echinococcus multilocularis synaptic vesicle 2 protein 0.006 0.0489 0.0583
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0425 0.4052 0.4842
Brugia malayi probable proline-trna synthetase - fission yeast, putative 0.0012 0.002 0.0047
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0245 0.1153
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0489 0.1196
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0014 0.0041 0.009
Trypanosoma brucei THT1 - hexose transporter, putative 0.0132 0.1192 1
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0014 0.0041 0.004
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0052 0.0411 0.041
Echinococcus granulosus glycine receptor subunit beta 0.0014 0.0041 0.0047
Loa Loa (eye worm) hypothetical protein 0.0014 0.0041 0.009
Echinococcus granulosus glycine receptor subunit alpha 1 0.0014 0.0041 0.0047
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0293 0.246
Trichomonas vaginalis sugar transporter, putative 0.006 0.0489 0.1196
Echinococcus multilocularis bloom syndrome protein 0.0063 0.0521 0.0621
Leishmania major DNA polymerase eta, putative 0.0014 0.0042 0.03
Brugia malayi sulfakinin receptor protein 0.0052 0.0411 0.1012
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0096 0.0839 0.2587
Echinococcus granulosus Sugar transporter ERD6 protein 0.006 0.0489 0.0583
Toxoplasma gondii lysine-tRNA ligase 0.0046 0.0359 0.0625
Brugia malayi follicle stimulating hormone receptor 0.0052 0.0411 0.1012
Schistosoma mansoni amine GPCR 0.0052 0.0411 0.041
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0064 0.0528 0.063
Mycobacterium ulcerans glycyl-tRNA synthetase 0.0012 0.002 0.0107
Mycobacterium tuberculosis Conserved protein 0.0035 0.0245 0.1153
Onchocerca volvulus 0.006 0.0489 0.1652
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0052 0.0411 0.0934
Echinococcus granulosus glycyl tRNA synthetase 0.0012 0.002 0.0023
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.0227 0.0558
Schistosoma mansoni neuropeptide receptor 0.0052 0.0411 0.041
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0425 0.4052 0.4842
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0222 0.2076 1
Brugia malayi hypothetical protein 0.0052 0.0411 0.1012
Echinococcus granulosus solute carrier family 22 0.006 0.0489 0.0583
Echinococcus granulosus tm gpcr rhodopsin 0.0052 0.0411 0.049
Schistosoma mansoni biogenic amine (5HT) receptor 0.0052 0.0411 0.041
Trypanosoma brucei glucose transporter, putative 0.0132 0.1192 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0041 0.009
Trichomonas vaginalis glucosylceramidase, putative 0.027 0.2545 0.6276
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0052 0.0411 0.041
Echinococcus granulosus neuropeptide receptor 0.0052 0.0411 0.049
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0014 0.0041 0.0047
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0014 0.0041 0.009
Loa Loa (eye worm) hypothetical protein 0.0052 0.0411 0.0934
Plasmodium falciparum calcium-dependent protein kinase 2 0.0064 0.0528 0.0614
Brugia malayi Sugar transporter family protein 0.0425 0.4052 1
Trichomonas vaginalis sugar transporter, putative 0.006 0.0489 0.1196
Brugia malayi polk-prov protein 0.003 0.0199 0.0488
Onchocerca volvulus 0.006 0.0489 0.1652
Echinococcus granulosus General substrate transporter 0.0365 0.3469 0.4145
Loa Loa (eye worm) hypothetical protein 0.0052 0.0411 0.0934
Schistosoma mansoni neuropeptide f receptor 76f 0.0052 0.0411 0.041
Onchocerca volvulus 0.0052 0.0411 0.1389
Loa Loa (eye worm) hypothetical protein 0.0062 0.0515 0.1172
Echinococcus multilocularis rhodopsin orphan GPCR 0.0052 0.0411 0.049
Brugia malayi major facilitator superfamily protein 0.006 0.0489 0.1204
Giardia lamblia Sgs1 DNA helicase, putative 0.0037 0.0269 0.0787
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0411 0.041
Trichomonas vaginalis conserved hypothetical protein 0.0425 0.4052 1
Echinococcus granulosus G protein coupled receptor 139 0.0052 0.0411 0.049
Leishmania major DNA polymerase epsilon catalytic subunit, putative 0.0018 0.0084 0.0651
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0411 0.041
Toxoplasma gondii DNA polymerase 0.0018 0.0084 0.0137
Trichomonas vaginalis sugar transporter, putative 0.006 0.0489 0.1196
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0052 0.0411 0.049
Loa Loa (eye worm) hypothetical protein 0.0014 0.0041 0.009
Echinococcus granulosus rhodopsin orphan GPCR 0.0052 0.0411 0.049
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0052 0.0411 0.049
Onchocerca volvulus 0.0052 0.0411 0.1389
Brugia malayi ImpB/MucB/SamB family protein 0.0014 0.0042 0.0102
Brugia malayi excitatory GABA receptor EXP-1A 0.0014 0.0041 0.0098
Loa Loa (eye worm) hypothetical protein 0.0014 0.0041 0.009
Loa Loa (eye worm) hypothetical protein 0.006 0.0489 0.1111
Echinococcus multilocularis rhodopsin orphan GPCR 0.0052 0.0411 0.049
Trichomonas vaginalis sugar transporter, putative 0.006 0.0489 0.1196
Loa Loa (eye worm) hypothetical protein 0.0459 0.4389 1
Toxoplasma gondii facilitative glucose transporter GT1 0.0425 0.4052 0.7172
Trichomonas vaginalis sugar transporter, putative 0.006 0.0489 0.1196
Brugia malayi Telomerase reverse transcriptase 0.0227 0.212 0.5231
Giardia lamblia DNA repair protein RAD52 0.0336 0.3185 1
Echinococcus granulosus orexin receptor type 2 0.0052 0.0411 0.049
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0282 0.2663 0.835
Echinococcus multilocularis GPCR, family 2 0.0015 0.0055 0.0064
Toxoplasma gondii sugar transporter ST3 0.006 0.0489 0.0855
Loa Loa (eye worm) hypothetical protein 0.0035 0.0245 0.0557
Echinococcus granulosus DNA polymerase delta catalytic subunit 0.0018 0.0084 0.0099
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0411 0.041
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0489 0.1196
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0105 0.0878
Echinococcus multilocularis Threonyl tRNA synthetase, C 0.0012 0.002 0.0023
Trichomonas vaginalis glucosylceramidase, putative 0.027 0.2545 0.6276
Loa Loa (eye worm) hypothetical protein 0.0052 0.0411 0.0934
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0104 0.0924 0.2278
Loa Loa (eye worm) hypothetical protein 0.006 0.0489 0.1111
Mycobacterium ulcerans beta-lactamase 0.0035 0.0245 0.1915
Loa Loa (eye worm) hypothetical protein 0.0052 0.0411 0.0934
Echinococcus granulosus neuropeptide Y receptor 0.0052 0.0411 0.049
Onchocerca volvulus 0.0052 0.0411 0.1389
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0014 0.0041 0.0047
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0037 0.0269 0.031
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0007 0.0005
Brugia malayi hypothetical protein 0.006 0.0489 0.1204
Echinococcus granulosus neuropeptides capa receptor 0.0052 0.0411 0.049
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0104 0.0919 0.2092
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0245 0.1153
Trichomonas vaginalis conserved hypothetical protein 0.0132 0.1192 0.2933
Entamoeba histolytica DNA polymerase delta catalytic subunit, putative 0.0018 0.0084 0.0202
Loa Loa (eye worm) hypothetical protein 0.0052 0.0411 0.0934
Echinococcus multilocularis neuropeptide Y receptor 0.0052 0.0411 0.049
Echinococcus multilocularis G protein coupled receptor 139 0.0052 0.0411 0.049
Giardia lamblia Telomerase catalytic subunit 0.0085 0.0738 0.2268
Trichomonas vaginalis sugar transporter, putative 0.006 0.0489 0.1196
Echinococcus multilocularis allatostatin A receptor 0.0052 0.0411 0.049
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0052 0.0411 0.1012
Loa Loa (eye worm) hypothetical protein 0.0035 0.0245 0.0557
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0293 0.246
Loa Loa (eye worm) neuropeptide F receptor 0.0052 0.0411 0.0934
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0043 0.0321 0.2654
Trypanosoma brucei glucose transporter, putative 0.0132 0.1192 1
Trypanosoma brucei THT1 - hexose transporter, putative 0.0132 0.1192 1
Brugia malayi hypothetical protein 0.0052 0.0411 0.1012
Loa Loa (eye worm) beta-lactamase 0.0035 0.0245 0.0557
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0046 0.0359 0.283
Echinococcus multilocularis dna polymerase eta 0.0014 0.0042 0.0049
Echinococcus granulosus solute carrier family 22 0.006 0.0489 0.0583
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0138 0.1253 1
Onchocerca volvulus 0.0052 0.0411 0.1389
Trypanosoma cruzi hexose transporter 0.0132 0.1192 1
Trichomonas vaginalis sugar transporter, putative 0.006 0.0489 0.1196
Plasmodium falciparum DNA polymerase delta catalytic subunit 0.0018 0.0084 0.0093
Brugia malayi hypothetical protein 0.006 0.0489 0.1204
Loa Loa (eye worm) hypothetical protein 0.0014 0.0042 0.0094
Schistosoma mansoni hypothetical protein 0.0425 0.4052 0.4051
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0046 0.0359 0.0876
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0014 0.0041 0.0047
Onchocerca volvulus 0.0014 0.0041 0.0134
Schistosoma mansoni protein kinase 0.0064 0.0528 0.0527
Plasmodium vivax DNA polymerase zeta catalytic subunit, putative 0.0018 0.0084 0.0075
Schistosoma mansoni biogenic amine (5HT) receptor 0.0413 0.3936 0.3936
Loa Loa (eye worm) hypothetical protein 0.0052 0.0411 0.0934
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0014 0.0041 0.009
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0052 0.0411 0.049
Echinococcus multilocularis rhodopsin orphan GPCR 0.0052 0.0411 0.049
Brugia malayi Cation transporter family protein 0.0014 0.0041 0.0098
Schistosoma mansoni DNA polymerase delta catalytic subunit 0.0018 0.0084 0.0083
Leishmania major myo-inositol/proton symporter (MIT) 0.006 0.0489 0.4068
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0064 0.0528 0.1301
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0293 0.2417
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0026 0.0156 0.0353
Toxoplasma gondii protein kinase, putative 0.0588 0.5647 1
Loa Loa (eye worm) hypothetical protein 0.006 0.0489 0.1111
Brugia malayi glycyl-tRNA synthetase 0.0012 0.002 0.0047
Loa Loa (eye worm) hypothetical protein 0.0052 0.0411 0.0934
Loa Loa (eye worm) hypothetical protein 0.0052 0.0411 0.0934
Onchocerca volvulus 0.0052 0.0411 0.1389
Toxoplasma gondii sugar transporter ST1 0.006 0.0489 0.0855
Echinococcus granulosus synaptic vesicle 2 protein 0.006 0.0489 0.0583
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0014 0.0041 0.009
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0062 0.0522
Leishmania major protein kinase, putative 0.0064 0.0528 0.4399
Echinococcus granulosus dro:myosuppressin receptor 0.0052 0.0411 0.049
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0048 0.0376 0.0925
Onchocerca volvulus 0.006 0.0489 0.1652
Brugia malayi Dopamine receptor 0.0052 0.0411 0.1012
Trichomonas vaginalis glucosylceramidase, putative 0.027 0.2545 0.6276
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0293 0.246
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0062 0.0522
Schistosoma mansoni hypothetical protein 0.0015 0.0055 0.0053
Loa Loa (eye worm) hypothetical protein 0.0143 0.1302 0.2963
Trypanosoma brucei glucose transporter, putative 0.0132 0.1192 1
Loa Loa (eye worm) flap endonuclease-1 0.0025 0.0151 0.0343
Echinococcus multilocularis solute carrier family 22 0.006 0.0489 0.0583
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0014 0.0041 0.0047
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0052 0.0411 0.041
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.006 0.0489 0.233
Mycobacterium tuberculosis Conserved protein 0.0035 0.0245 0.1153
Loa Loa (eye worm) hypothetical protein 0.0014 0.0041 0.009
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0052 0.0411 0.041
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0014 0.0041 0.0098
Loa Loa (eye worm) hypothetical protein 0.006 0.0489 0.1111
Echinococcus granulosus biogenic amine 5HT receptor 0.0413 0.3936 0.4704
Trichomonas vaginalis sugar transporter, putative 0.006 0.0489 0.1196
Brugia malayi threonyl-tRNA synthetase, cytoplasmic 0.0012 0.002 0.0047
Brugia malayi putative neuropeptide receptor 0.0052 0.0411 0.1012
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0245 0.0244
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0014 0.0041 0.0098
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.2663 0.6567
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0052 0.0411 0.049
Schistosoma mansoni hypothetical protein 0.0033 0.0227 0.0226
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0425 0.4052 0.4842
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0245 0.0557
Loa Loa (eye worm) hypothetical protein 0.0052 0.0411 0.0934
Onchocerca volvulus 0.006 0.0489 0.1652
Brugia malayi hypothetical protein 0.006 0.0489 0.1204
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0245 0.1153
Treponema pallidum prolyl-tRNA synthetase 0.0022 0.0121 0.0382
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0245 0.1915
Loa Loa (eye worm) hypothetical protein 0.0052 0.0411 0.0934
Brugia malayi hypothetical protein 0.0052 0.0411 0.1012
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0012 0.002 0.0112
Loa Loa (eye worm) hypothetical protein 0.0048 0.0376 0.0854
Schistosoma mansoni nAChR subunit 0.0014 0.0041 0.004
Schistosoma mansoni hypothetical protein 0.0052 0.0411 0.041
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0014 0.0041 0.0098
Echinococcus multilocularis sex peptide receptor 0.0052 0.0411 0.049
Trypanosoma brucei THT1 - hexose transporter, putative 0.0132 0.1192 1
Brugia malayi DNA polymerase family B containing protein 0.0018 0.0084 0.0204
Plasmodium vivax ATP-dependent DNA helicase Q1, putative 0.0018 0.0084 0.0075
Echinococcus granulosus serotonin receptor 0.0052 0.0411 0.049
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0014 0.0041 0.004
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0014 0.0041 0.0098
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0073 0.0617 0.5145
Echinococcus granulosus DNA polymerase alpha catalytic subunit 0.0018 0.0084 0.0099
Loa Loa (eye worm) hypothetical protein 0.0052 0.0411 0.0934
Trypanosoma brucei DNA polymerase delta catalytic subunit, putative 0.0018 0.0084 0.0704
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0014 0.0041 0.004
Plasmodium falciparum proline--tRNA ligase 0.0073 0.0617 0.0718
Loa Loa (eye worm) G-protein coupled receptor 0.0052 0.0411 0.0934
Toxoplasma gondii transporter, major facilitator family protein 0.006 0.0489 0.0855
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0052 0.0411 0.1012
Echinococcus multilocularis geminin 0.0341 0.3236 0.3867
Onchocerca volvulus DNA polymerase homolog 0.0018 0.0084 0.028
Loa Loa (eye worm) hypothetical protein 0.0052 0.0411 0.0934
Brugia malayi Latrophilin receptor protein 2 0.0015 0.0055 0.0132
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0015 0.0055 0.0132
Schistosoma mansoni sugar transporter 0.006 0.0489 0.0488
Trichomonas vaginalis sugar transporter, putative 0.006 0.0489 0.1196
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0052 0.0411 0.041
Trypanosoma cruzi DNA polymerase epsilon catalytic subunit, putative 0.0018 0.0084 0.0651
Loa Loa (eye worm) neuropeptide F receptor 0.0052 0.0411 0.0934
Echinococcus multilocularis DNA polymerase delta catalytic subunit 0.0018 0.0084 0.0099
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0293 0.246
Trypanosoma cruzi hexose transporter, putative 0.0132 0.1192 1
Loa Loa (eye worm) hypothetical protein 0.0051 0.0401 0.0912
Echinococcus multilocularis dna polymerase kappa 0.004 0.0293 0.0349
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0336 0.319 0.3724
Trichomonas vaginalis glucose transporter, putative 0.0132 0.1192 0.2933
Echinococcus granulosus neuropeptide Y receptor 0.0052 0.0411 0.049
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0064 0.0528 0.0597
Loa Loa (eye worm) hypothetical protein 0.0014 0.0041 0.009
Loa Loa (eye worm) hypothetical protein 0.0012 0.002 0.0043
Schistosoma mansoni glucose transport protein 0.0425 0.4052 0.4051
Trichomonas vaginalis sugar transporter, putative 0.006 0.0489 0.1196
Onchocerca volvulus 0.0052 0.0411 0.1389
Schistosoma mansoni DNA helicase recq5 0.0037 0.0269 0.0268
Echinococcus multilocularis rhodopsin orphan GPCR 0.0052 0.0411 0.049
Mycobacterium ulcerans threonyl-tRNA synthetase 0.0012 0.002 0.0107
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0039 0.0291 0.1374
Onchocerca volvulus 0.006 0.0489 0.1652
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0293 0.2417
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0052 0.0411 0.049
Trichomonas vaginalis sugar transporter, putative 0.006 0.0489 0.1196
Schistosoma mansoni nAChR subunit 0.0014 0.0041 0.004
Loa Loa (eye worm) hypothetical protein 0.006 0.0489 0.1111
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0245 0.0292
Brugia malayi AKH receptor 0.0052 0.0411 0.1012
Loa Loa (eye worm) hypothetical protein 0.0052 0.0411 0.0934
Echinococcus granulosus 7TM GPCR rhodopsin 0.0052 0.0411 0.049
Schistosoma mansoni hypothetical protein 0.0341 0.3236 0.3235
Onchocerca volvulus 0.0052 0.0411 0.1389
Trichomonas vaginalis flap endonuclease-1, putative 0.0025 0.0151 0.0363
Loa Loa (eye worm) hypothetical protein 0.0035 0.0245 0.0557
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0014 0.0042 0.0041
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0015 0.0055 0.0064
Echinococcus granulosus tm gpcr rhodopsin 0.0867 0.8367 1
Trypanosoma cruzi DNA polymerase delta catalytic subunit, putative 0.0018 0.0084 0.0651
Loa Loa (eye worm) hypothetical protein 0.0052 0.0411 0.0934
Mycobacterium leprae conserved hypothetical protein 0.0035 0.0245 0.1915
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0039 0.0291 0.2281
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0037 0.0269 0.0465
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0025 0.0151 0.0256
Loa Loa (eye worm) hypothetical protein 0.0052 0.0411 0.0934
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0014 0.0042 0.0094
Trichomonas vaginalis sugar transporter, putative 0.006 0.0489 0.1196
Schistosoma mansoni adenoreceptor 0.0052 0.0411 0.041
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0014 0.0041 0.0047
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.002 0.0105 0.0825
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0245 0.2014
Schistosoma mansoni nAChR subunit 0.0014 0.0041 0.004
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0052 0.0411 0.1012
Loa Loa (eye worm) TYRA-2 protein 0.0052 0.0411 0.0934
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0039 0.0291 0.1374
Brugia malayi Bloom's syndrome protein homolog 0.0063 0.0521 0.1282
Brugia malayi Sugar transporter family protein 0.006 0.0489 0.1204
Toxoplasma gondii DNA polymerase (pol2) superfamily protein 0.0018 0.0084 0.0137
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0052 0.0411 0.049
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0014 0.0041 0.0098
Plasmodium vivax telomerase reverse transcriptase, putative 0.0085 0.0738 0.0843
Echinococcus granulosus lysyl tRNA synthetase 0.0046 0.0359 0.0428
Loa Loa (eye worm) hypothetical protein 0.0019 0.0091 0.0205
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0037 0.0269 0.0611
Schistosoma mansoni protein kinase 0.0064 0.0528 0.0527
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0037 0.0269 0.0321
Onchocerca volvulus 0.0052 0.0411 0.1389
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0011 0.001 0.0006
Echinococcus granulosus GPCR family 2 0.0015 0.0055 0.0064
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.006 0.0489 0.233
Echinococcus granulosus biogenic amine 5HT receptor 0.0052 0.0411 0.049
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0425 0.4052 0.4842
Schistosoma mansoni DNA polymerase zeta catalytic subunit 0.0018 0.0084 0.0083
Mycobacterium tuberculosis Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase)(ThrRS) (threonine-tRNA ligase) 0.0012 0.002 0.0064
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0064 0.0528 0.0925
Trichomonas vaginalis glucose transporter, putative 0.006 0.0489 0.1196
Loa Loa (eye worm) hypothetical protein 0.0014 0.0041 0.009
Trichomonas vaginalis DNA polymerase alpha catalytic subunit, putative 0.0018 0.0084 0.0196
Trypanosoma brucei DNA polymerase alpha catalytic subunit 0.0018 0.0084 0.0704
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0245 0.1915
Trichomonas vaginalis glucosylceramidase, putative 0.0187 0.1731 0.4264
Echinococcus multilocularis serotonin receptor 0.0413 0.3936 0.4704
Schistosoma mansoni neuropeptide F-like receptor 0.0052 0.0411 0.041
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0062 0.0515 0.4083
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0425 0.4052 0.4842
Loa Loa (eye worm) ACC-1 protein 0.0014 0.0041 0.009
Brugia malayi Cation transporter family protein 0.0014 0.0041 0.0098
Echinococcus multilocularis lysyl tRNA synthetase 0.0046 0.0359 0.0428
Schistosoma mansoni neuropeptide receptor 0.0052 0.0411 0.041
Echinococcus granulosus peptide allatostatin:somatostatin 0.0052 0.0411 0.049
Trichomonas vaginalis CAMK family protein kinase 0.0064 0.0528 0.1293
Trichomonas vaginalis sugar transporter, putative 0.006 0.0489 0.1196
Trichomonas vaginalis sugar transporter, putative 0.0132 0.1192 0.2933
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.006 0.0489 0.3869
Schistosoma mansoni sugar transporter 0.006 0.0489 0.0488
Loa Loa (eye worm) hypothetical protein 0.0052 0.0411 0.0934
Schistosoma mansoni hypothetical protein 0.0052 0.0411 0.041
Loa Loa (eye worm) hypothetical protein 0.0014 0.0041 0.009
Entamoeba histolytica recQ family helicase, putative 0.0043 0.0321 0.0951
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0064 0.0528 0.4431
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0489 0.1196
Schistosoma mansoni serine/threonine protein kinase 0.0064 0.0528 0.0527
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0058 0.0469 0.0544
Trichomonas vaginalis glucosylceramidase, putative 0.027 0.2545 0.6276
Trichomonas vaginalis myo-inositol transporter, putative 0.006 0.0489 0.1196
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0014 0.0041 0.004
Trichomonas vaginalis sugar transporter, putative 0.006 0.0489 0.1196
Brugia malayi Dopamine receptor protein 2 0.0052 0.0411 0.1012
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0014 0.0041 0.0047
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0425 0.4052 0.4842
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0052 0.0411 0.049
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.1637 0.4034
Onchocerca volvulus 0.0014 0.0041 0.0134
Loa Loa (eye worm) hypothetical protein 0.0064 0.0528 0.1201
Leishmania major lysyl-tRNA synthetase, putative 0.0046 0.0359 0.2975
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0199 0.167
Echinococcus multilocularis Sugar transporter ERD6 protein 0.006 0.0489 0.0583
Echinococcus multilocularis orexin receptor type 2 0.0052 0.0411 0.049
Trypanosoma brucei DNA polymerase epsilon catalytic subunit, putative 0.0018 0.0084 0.0704
Schistosoma mansoni opsin-like receptor 0.0052 0.0411 0.041
Loa Loa (eye worm) hypothetical protein 0.0014 0.0041 0.009
Onchocerca volvulus 0.0052 0.0411 0.1389
Trypanosoma brucei glucose transporter, putative 0.0132 0.1192 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0055 0.0122
Toxoplasma gondii sugar transporter ST2 0.006 0.0489 0.0855
Loa Loa (eye worm) DNA-directed DNA polymerase III 0.0018 0.0084 0.0189
Schistosoma mansoni histamine h1 receptor 0.0052 0.0411 0.041
Giardia lamblia Prolyl-tRNA synthetase 0.0062 0.0515 0.1565
Schistosoma mansoni hypothetical protein 0.0052 0.0411 0.041
Brugia malayi G protein-coupled receptor F59B2.13 0.0052 0.0411 0.1012
Schistosoma mansoni hypothetical protein 0.0015 0.0055 0.0053
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0037 0.0269 0.0662
Onchocerca volvulus 0.006 0.0489 0.1652
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0022 0.0121 0.0918
Trichomonas vaginalis sugar transporter, putative 0.006 0.0489 0.1196
Leishmania major DNA polymerase kappa, putative 0.002 0.0105 0.0825
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0052 0.0411 0.049
Trichomonas vaginalis sugar transporter, putative 0.006 0.0489 0.1196
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0293 0.246
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0014 0.0041 0.0098
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0293 0.246
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0015 0.0055 0.0064
Loa Loa (eye worm) hypothetical protein 0.006 0.0489 0.1111
Schistosoma mansoni glycyl-tRNA synthetase 0.0012 0.002 0.0019
Schistosoma mansoni alpha-1 adrenergic receptor 0.0052 0.0411 0.041
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0041 0.0304 0.0738
Echinococcus granulosus somatostatin receptor 0.0052 0.0411 0.049
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0245 0.0265
Echinococcus granulosus Threonyl tRNA synthetase C 0.0012 0.002 0.0023
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0014 0.0041 0.0047
Echinococcus granulosus DNA polymerase zeta catalytic subunit 0.0018 0.0084 0.0099
Entamoeba histolytica recQ family helicase, putative 0.0018 0.0084 0.0202
Trypanosoma cruzi DNA polymerase eta, putative 0.0014 0.0042 0.03
Loa Loa (eye worm) hypothetical protein 0.0014 0.0041 0.009
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.2663 0.6567
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0199 0.167
Trichomonas vaginalis sugar transporter, putative 0.006 0.0489 0.1196
Onchocerca volvulus 0.0035 0.0245 0.0828
Echinococcus multilocularis g-protein coupled receptor 0.0052 0.0411 0.049
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0062 0.0515 0.1262
Loa Loa (eye worm) hypothetical protein 0.006 0.0489 0.1111
Echinococcus granulosus neuropeptides capa receptor 0.0052 0.0411 0.049
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0052 0.0411 0.049
Trichomonas vaginalis DNA polymerase zeta catalytic subunit, putative 0.0018 0.0084 0.0196
Schistosoma mansoni neuropeptide receptor 0.0052 0.0411 0.041
Leishmania major hypothetical protein, conserved 0.006 0.0489 0.4068
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0245 0.0595
Leishmania major threonyl-tRNA synthetase, putative 0.0012 0.002 0.0112
Echinococcus multilocularis glycyl tRNA synthetase 0.0012 0.002 0.0023
Onchocerca volvulus 0.0014 0.0041 0.0134
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0245 0.0595
Loa Loa (eye worm) RecQ helicase 0.0063 0.0521 0.1184
Echinococcus multilocularis neuropeptide receptor 0.0052 0.0411 0.049
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.006 0.0489 0.0568
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.2663 0.6567
Trypanosoma cruzi DNA polymerase I alpha catalytic subunit, putative 0.0018 0.0084 0.0651
Treponema pallidum fructose-bisphosphate aldolase 0.0282 0.2663 1
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0425 0.4052 0.4842
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0245 0.206
Loa Loa (eye worm) hypothetical protein 0.0052 0.0411 0.0934
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0012 0.002 0.0112
Schistosoma mansoni nAChR subunit 0.0014 0.0041 0.004
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0138 0.1253 1
Loa Loa (eye worm) major facilitator superfamily transporter 0.006 0.0489 0.1111
Trichomonas vaginalis sugar transporter, putative 0.006 0.0489 0.1196
Echinococcus granulosus fmrfamide receptor 0.0052 0.0411 0.049
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0064 0.0528 0.1201
Plasmodium falciparum calcium-dependent protein kinase 4 0.0064 0.0528 0.0614
Mycobacterium tuberculosis Conserved hypothetical protein 0.0014 0.0042 0.0172
Onchocerca volvulus 0.0052 0.0411 0.1389
Trichomonas vaginalis glucosylceramidase, putative 0.0187 0.1731 0.4264
Echinococcus granulosus transcription factor eb 0.0104 0.0924 0.1103
Loa Loa (eye worm) hypothetical protein 0.0018 0.0084 0.0189
Loa Loa (eye worm) hypothetical protein 0.006 0.0489 0.1111
Schistosoma mansoni sugar transporter 0.006 0.0489 0.0488
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0336 0.3185 1
Trypanosoma cruzi glucose transporter, putative 0.006 0.0489 0.4068
Loa Loa (eye worm) hypothetical protein 0.0052 0.0411 0.0934
Echinococcus multilocularis General substrate transporter 0.0365 0.3469 0.4145
Schistosoma mansoni blooms syndrome DNA helicase 0.0044 0.0335 0.0334
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0014 0.0041 0.0098
Leishmania major telomerase reverse transcriptase, putative 0.0085 0.0738 0.617
Echinococcus granulosus tachykinin peptides receptor 99D 0.0052 0.0411 0.049
Trypanosoma brucei DNA polymerase zeta catalytic subunit, putative 0.0018 0.0084 0.0704
Entamoeba histolytica Flap nuclease, putative 0.0025 0.0151 0.0415
Loa Loa (eye worm) hypothetical protein 0.0014 0.0041 0.009
Schistosoma mansoni neuropeptide receptor 0.0052 0.0411 0.041
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0014 0.0041 0.0047
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.0085 0.0738 0.617
Onchocerca volvulus 0.0052 0.0411 0.1389
Echinococcus multilocularis solute carrier family 22 0.006 0.0489 0.0583
Trichomonas vaginalis sugar transporter, putative 0.006 0.0489 0.1196
Echinococcus multilocularis fmrfamide receptor 0.0052 0.0411 0.049
Loa Loa (eye worm) hypothetical protein 0.0413 0.3936 0.8968
Trichomonas vaginalis glucosylceramidase, putative 0.027 0.2545 0.6276
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0014 0.0041 0.009
Schistosoma mansoni lysyl-tRNA synthetase 0.0046 0.0359 0.0358
Echinococcus multilocularis transcription factor eb 0.0104 0.0924 0.1103
Brugia malayi hypothetical protein 0.0052 0.0411 0.1012
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0245 0.0595
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0014 0.0041 0.0098
Loa Loa (eye worm) hypothetical protein 0.0035 0.0245 0.0557
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0015 0.0055 0.0064
Leishmania major glucose transporter, lmgt1 0.0132 0.1192 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0048 0.0376 0.0854
Trypanosoma brucei glucose transporter, putative 0.0132 0.1192 1
Echinococcus granulosus neuropeptide FF receptor 2 0.0052 0.0411 0.049
Chlamydia trachomatis proline--tRNA ligase 0.0022 0.0121 0.2978
Schistosoma mansoni DNA helicase recq1 0.0037 0.0269 0.0268
Loa Loa (eye worm) hypothetical protein 0.0052 0.0411 0.0934
Trichomonas vaginalis sugar transporter, putative 0.0132 0.1192 0.2933
Giardia lamblia Lysyl-tRNA synthetase 0.0046 0.0359 0.1072
Plasmodium falciparum hexose transporter 0.0425 0.4052 0.4747
Brugia malayi N-terminal motif family protein 0.0189 0.1751 0.4319
Loa Loa (eye worm) hypothetical protein 0.0052 0.0411 0.0934
Onchocerca volvulus 0.006 0.0489 0.1652
Brugia malayi Serotonin receptor 0.0052 0.0411 0.1012
Loa Loa (eye worm) hypothetical protein 0.0052 0.0411 0.0934
Brugia malayi Cam kinase protein 1 0.0064 0.0528 0.1301
Echinococcus multilocularis serotonin receptor 0.0413 0.3936 0.4704
Trypanosoma brucei Aminoacyl-tRNA editing domain containing protein, putative 0.001 0.0007 0.0058
Schistosoma mansoni terminal deoxycytidyl transferase 0.0014 0.0042 0.0041
Echinococcus multilocularis neuropeptides capa receptor 0.0052 0.0411 0.049
Mycobacterium ulcerans sugar transporter 0.006 0.0489 0.3869
Loa Loa (eye worm) hypothetical protein 0.0035 0.0245 0.0557
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0062 0.0515 0.0615
Trichomonas vaginalis sugar transporter, putative 0.006 0.0489 0.1196
Trichomonas vaginalis DNA polymerase delta catalytic subunit, putative 0.0018 0.0084 0.0196
Entamoeba histolytica hypothetical protein 0.0096 0.0839 0.2587
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0064 0.0528 0.063
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.2663 0.6567
Trichomonas vaginalis sugar transport protein, putative 0.006 0.0489 0.1196
Loa Loa (eye worm) hypothetical protein 0.0014 0.0041 0.009
Schistosoma mansoni lysyl-tRNA synthetase 0.0046 0.0359 0.0358
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.006 0.0489 0.0488
Trichomonas vaginalis DNA polymerase eta, putative 0.004 0.0293 0.0713
Trichomonas vaginalis sugar transporter, putative 0.006 0.0489 0.1196
Onchocerca volvulus 0.0014 0.0041 0.0134
Echinococcus granulosus tm gpcr rhodopsin 0.0052 0.0411 0.049
Echinococcus multilocularis somatostatin receptor 0.0052 0.0411 0.049
Schistosoma mansoni flap endonuclease-1 0.0023 0.0128 0.0127
Leishmania major hypothetical protein, conserved 0.0035 0.0245 0.2014
Loa Loa (eye worm) G-protein coupled receptor 0.0052 0.0411 0.0934
Loa Loa (eye worm) hypothetical protein 0.0014 0.0041 0.009
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0411 0.041
Echinococcus granulosus alpha 1A adrenergic receptor 0.0052 0.0411 0.049
Onchocerca volvulus Telomerase reverse transcriptase homolog 0.0312 0.2952 1
Plasmodium falciparum protein kinase 7 0.0588 0.5647 0.6618
Loa Loa (eye worm) hypothetical protein 0.0035 0.0245 0.0557
Onchocerca volvulus 0.0035 0.0245 0.0828
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0014 0.0041 0.0047
Onchocerca volvulus DNA polymerase alpha catalytic subunit homolog 0.0018 0.0084 0.028
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.006 0.0489 0.3869
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0245 0.0603
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0293 0.2417
Loa Loa (eye worm) hypothetical protein 0.003 0.0199 0.0451
Loa Loa (eye worm) hypothetical protein 0.0014 0.0041 0.009
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.006 0.0489 0.4102
Echinococcus granulosus dna polymerase eta 0.0014 0.0042 0.0049
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0064 0.0528 0.063
Echinococcus granulosus g-protein coupled receptor 0.0052 0.0411 0.049
Onchocerca volvulus 0.006 0.0489 0.1652
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0014 0.0041 0.0047
Echinococcus granulosus sex peptide receptor 0.0052 0.0411 0.049
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.1637 0.4034
Loa Loa (eye worm) hypothetical protein 0.0052 0.0411 0.0934
Echinococcus multilocularis g protein coupled receptor 0.0052 0.0411 0.049
Onchocerca volvulus 0.0052 0.0411 0.1389
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.1637 0.4034
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0064 0.0528 0.0925
Giardia lamblia DNA polymerase epsilon, catalytic subunit 0.0018 0.0084 0.0202
Echinococcus multilocularis rhodopsin orphan GPCR 0.0052 0.0411 0.049
Onchocerca volvulus Putative nachr subunit 0.0014 0.0041 0.0134
Loa Loa (eye worm) hypothetical protein 0.006 0.0489 0.1111
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0189 0.1751 0.5928
Onchocerca volvulus 0.006 0.0489 0.1652
Schistosoma mansoni amine GPCR 0.0052 0.0411 0.041
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0073 0.0617 0.5145
Brugia malayi neuropeptide F receptor 0.0052 0.0411 0.1012
Echinococcus granulosus 7tm_1 domain containing protein 0.0052 0.0411 0.049
Echinococcus multilocularis neuropeptide receptor 0.0052 0.0411 0.049
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0052 0.0411 0.0934
Plasmodium falciparum flap endonuclease 1 0.0025 0.0151 0.0172
Brugia malayi beta-lactamase family protein 0.0035 0.0245 0.0603
Echinococcus multilocularis nAChR subunit 0.0014 0.0041 0.0047
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0064 0.0528 0.063
Echinococcus granulosus neuropeptide receptor 0.0052 0.0411 0.049
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0014 0.0042 0.0049
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0052 0.0411 0.041
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0052 0.0411 0.049
Echinococcus multilocularis neuropeptides capa receptor 0.0052 0.0411 0.049
Trypanosoma brucei glucose transporter, putative 0.0132 0.1192 1
Treponema pallidum ATP-dependent DNA helicase 0.0019 0.0091 0.0269
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.027 0.2545 0.6279
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0245 0.2014
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0293 0.2299
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0245 0.1153
Onchocerca volvulus 0.0052 0.0411 0.1389
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0282 0.2663 0.835
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.2663 0.6567
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.2663 0.6567
Entamoeba histolytica recQ family DNA helicase 0.0019 0.0091 0.0224
Plasmodium vivax CDK-related protein kinase 6, putative 0.0883 0.8531 1
Loa Loa (eye worm) hypothetical protein 0.0459 0.4389 1
Onchocerca volvulus Putative transporter 0.006 0.0489 0.1652
Loa Loa (eye worm) hypothetical protein 0.0052 0.0411 0.0934
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0014 0.0041 0.0098
Schistosoma mansoni DNA polymerase eta 0.0014 0.0042 0.0041
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0062 0.0522
Onchocerca volvulus 0.006 0.0489 0.1652
Echinococcus multilocularis dna polymerase epsilon catalytic subunit a 0.0018 0.0084 0.0099
Loa Loa (eye worm) hypothetical protein 0.006 0.0489 0.1111
Echinococcus granulosus geminin 0.0341 0.3236 0.3867
Loa Loa (eye worm) hypothetical protein 0.0052 0.0411 0.0934
Trichomonas vaginalis sugar transporter, putative 0.006 0.0489 0.1196
Plasmodium vivax flap endonuclease 1, putative 0.0025 0.0151 0.0154
Loa Loa (eye worm) hypothetical protein 0.0014 0.0041 0.009

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 60 ug ml-1 Cytostatic activity against chronic myelogenous leukemia cells (K-562) based on its ability to inhibit [3H]-thymidine incorporation ChEMBL. 11882008
IC50 (functional) = 60 ug ml-1 Cytostatic activity against chronic myelogenous leukemia cells (K-562) based on its ability to inhibit [3H]-thymidine incorporation ChEMBL. 11882008
Inhibition (functional) = 22 % Percent inhibition of M. tuberculosis H37Rv at 6.25 g/ml concentration in BACTEC 12B medium using microplate alamar blue assay ChEMBL. 11882008
Inhibition (functional) = 22 % Percent inhibition of M. tuberculosis H37Rv at 6.25 g/ml concentration in BACTEC 12B medium using microplate alamar blue assay ChEMBL. 11882008
ND (functional) 0 Antibacterial activity against M. tuberculosis H37Rv in BACTEC 12B medium using microplate alamar blue assay;ND means not determined. ChEMBL. 11882008
ND (functional) 0 Minimum inhibitory concentration for testing cytotoxicity in VERO cells;ND means not determined. ChEMBL. 11882008
ND (functional) 0 Selectivity Index,SI = IC50:MIC.ND means not determined. ChEMBL. 11882008

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.