Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase, putative | 0.019 | 0.1213 | 0.1234 |
Loa Loa (eye worm) | hypothetical protein | 0.0119 | 0.0701 | 0.0713 |
Wolbachia endosymbiont of Brugia malayi | FKBP-type peptidylprolyl isomerase | 0.019 | 0.1213 | 0.5 |
Toxoplasma gondii | aspartyl proteinase (eimepsin), putative | 0.0505 | 0.3485 | 1 |
Schistosoma mansoni | DNAj homolog subfamily C member | 0.0028 | 0.0043 | 0.0043 |
Schistosoma mansoni | glutamate receptor NMDA | 0.0025 | 0.0018 | 0.0018 |
Plasmodium falciparum | plasmepsin III | 0.0119 | 0.0701 | 0.0713 |
Trichomonas vaginalis | fk506-binding protein, putative | 0.1383 | 0.9825 | 1 |
Loa Loa (eye worm) | TPR Domain containing protein | 0.0024 | 0.0013 | 0.0013 |
Trypanosoma cruzi | stress-inducible protein STI1-like, putative | 0.0024 | 0.0013 | 0.0014 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.003 | 0.0052 | 0.0052 |
Toxoplasma gondii | aspartyl protease ASP3 | 0.0119 | 0.0701 | 0.201 |
Echinococcus granulosus | small glutamine rich tetratricopeptide | 0.0024 | 0.0013 | 0.0013 |
Loa Loa (eye worm) | hypothetical protein | 0.0119 | 0.0701 | 0.0713 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0119 | 0.0701 | 0.0701 |
Trichomonas vaginalis | immunophilin, putative | 0.1383 | 0.9825 | 1 |
Onchocerca volvulus | 0.0024 | 0.0013 | 0.0106 | |
Brugia malayi | hypothetical protein | 0.0024 | 0.0013 | 0.0013 |
Brugia malayi | hypothetical protein | 0.0119 | 0.0701 | 0.0711 |
Schistosoma mansoni | fk506 binding protein | 0.019 | 0.1213 | 0.1213 |
Trichomonas vaginalis | O-linked N-acetylglucosamine transferase, ogt, putative | 0.0028 | 0.0043 | 0.0043 |
Echinococcus multilocularis | glutamate receptor subunit protein glur | 0.0051 | 0.0207 | 0.0207 |
Trypanosoma cruzi | FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative | 0.1383 | 0.9825 | 1 |
Leishmania major | FKBP-type peptidyl-prolyl cis-trans isomerase, putative | 0.019 | 0.1213 | 0.1234 |
Trichomonas vaginalis | chaperone binding protein, putative | 0.0024 | 0.0013 | 0.0013 |
Entamoeba histolytica | peptidyl-prolyl cis-trans isomerase, putative | 0.019 | 0.1213 | 0.1213 |
Plasmodium falciparum | plasmepsin IV | 0.0505 | 0.3485 | 0.3547 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0067 | 0.032 | 0.032 |
Brugia malayi | Pepsin A precursor | 0.0119 | 0.0701 | 0.0711 |
Plasmodium vivax | plasmepsin V, putative | 0.0119 | 0.0701 | 0.0713 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0141 | 0.0143 |
Schistosoma mansoni | protein phosphatase-5 | 0.0024 | 0.0013 | 0.0013 |
Echinococcus granulosus | STIP1 y and U box containing protein 1 | 0.0024 | 0.0013 | 0.0013 |
Echinococcus multilocularis | small glutamine rich tetratricopeptide | 0.0024 | 0.0013 | 0.0013 |
Brugia malayi | TPR Domain containing protein | 0.0024 | 0.0013 | 0.0013 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0062 | 0.0288 | 0.0288 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0119 | 0.0701 | 0.0701 |
Schistosoma mansoni | hypothetical protein | 0.019 | 0.1213 | 0.1213 |
Echinococcus multilocularis | glutamate receptor 4 | 0.0042 | 0.0141 | 0.0141 |
Schistosoma mansoni | glutamate receptor AMPA | 0.0025 | 0.0018 | 0.0018 |
Schistosoma mansoni | heat shock protein 70 | 0.0024 | 0.0013 | 0.0013 |
Echinococcus multilocularis | mitochondrial import receptor subunit tom34 | 0.0024 | 0.0013 | 0.0013 |
Giardia lamblia | FKBP-type peptidyl-prolyl cis-trans isomerase | 0.019 | 0.1213 | 0.1223 |
Brugia malayi | FKBP-type peptidyl-prolyl cis-trans isomerase-33, BmFKBP-33 | 0.019 | 0.1213 | 0.1231 |
Plasmodium falciparum | plasmepsin VIII, putative | 0.0119 | 0.0701 | 0.0713 |
Echinococcus multilocularis | fk506 binding protein | 0.1383 | 0.9825 | 0.9825 |
Mycobacterium leprae | PROBABLE TRIGGER FACTOR (TF) PROTEIN TIG | 0.019 | 0.1213 | 0.5 |
Giardia lamblia | 70 kDa peptidylprolyl isomerase, putative | 0.1383 | 0.9825 | 1 |
Plasmodium falciparum | Hsp70/Hsp90 organizing protein | 0.0024 | 0.0013 | 0.0014 |
Echinococcus granulosus | peptidyl prolyl cis trans isomerase FKBP4 | 0.1217 | 0.8626 | 0.8626 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0119 | 0.0701 | 0.0701 |
Loa Loa (eye worm) | hypothetical protein | 0.019 | 0.1213 | 0.1234 |
Brugia malayi | FKBP-type peptidyl-prolyl cis-trans isomerase-13, BmFKBP-13 | 0.019 | 0.1213 | 0.1231 |
Schistosoma mansoni | immunophilin FK506 binding protein FKBP12 | 0.1383 | 0.9825 | 0.9825 |
Entamoeba histolytica | heat shock protein STI1, putative | 0.0024 | 0.0013 | 0.0013 |
Trypanosoma cruzi | FKBP-type peptidylprolyl cis-trans isomerase, putative | 0.019 | 0.1213 | 0.1234 |
Brugia malayi | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase | 0.0024 | 0.0013 | 0.0014 |
Toxoplasma gondii | peptidyl-prolyl isomerase FKBP12, putative | 0.019 | 0.1213 | 0.3481 |
Schistosoma mansoni | glutamate receptor kainate | 0.0025 | 0.0018 | 0.0018 |
Giardia lamblia | FKBP-type peptidyl-prolyl cis-trans isomerase | 0.019 | 0.1213 | 0.1223 |
Schistosoma mansoni | glutamate receptor AMPA | 0.0025 | 0.0018 | 0.0018 |
Echinococcus granulosus | glutamate receptor subunit protein glur | 0.0051 | 0.0207 | 0.0207 |
Echinococcus granulosus | FK506 binding protein 8 38 kDa | 0.019 | 0.1213 | 0.1213 |
Schistosoma mansoni | glutamate receptor kainate | 0.0025 | 0.0018 | 0.0018 |
Mycobacterium ulcerans | FK-506 binding protein, peptidyl-prolyl cis-trans isomerase | 0.1383 | 0.9825 | 1 |
Schistosoma mansoni | ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related | 0.0024 | 0.0013 | 0.0013 |
Loa Loa (eye worm) | aspartic protease BmAsp-1 | 0.0119 | 0.0701 | 0.0713 |
Schistosoma mansoni | o-linked n-acetylglucosamine transferase ogt | 0.0024 | 0.0013 | 0.0013 |
Treponema pallidum | peptidyl-prolyl cis-trans isomerase, FKBP-type, 22 kDa (fklB) | 0.1383 | 0.9825 | 1 |
Toxoplasma gondii | aspartyl protease | 0.0119 | 0.0701 | 0.201 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0119 | 0.0701 | 0.0701 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0505 | 0.3485 | 0.3485 |
Plasmodium vivax | aspartyl proteinase, putative | 0.0505 | 0.3485 | 0.3547 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.003 | 0.0052 | 0.0052 |
Echinococcus multilocularis | glutamate (NMDA) receptor subunit | 0.0025 | 0.0018 | 0.0018 |
Wolbachia endosymbiont of Brugia malayi | FKBP-type peptidylprolyl isomerase | 0.019 | 0.1213 | 0.5 |
Echinococcus multilocularis | Tetratricopeptide repeat protein 1 | 0.0024 | 0.0013 | 0.0013 |
Brugia malayi | aspartic protease BmAsp-2, identical | 0.0119 | 0.0701 | 0.0711 |
Loa Loa (eye worm) | glutamate receptor 1 | 0.0067 | 0.032 | 0.0326 |
Toxoplasma gondii | peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein | 0.019 | 0.1213 | 0.3481 |
Leishmania major | small glutamine-rich tetratricopeptide repeat protein, putative | 0.0024 | 0.0013 | 0.0014 |
Schistosoma mansoni | memapsin-2 (A01 family) | 0.0119 | 0.0701 | 0.0701 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0071 | 0.0354 | 0.0354 |
Giardia lamblia | Hypothetical protein | 0.019 | 0.1213 | 0.1223 |
Brugia malayi | Glutamate receptor 2 precursor | 0.0067 | 0.032 | 0.0325 |
Plasmodium falciparum | plasmepsin I | 0.0505 | 0.3485 | 0.3547 |
Echinococcus multilocularis | O glycosyltransferase | 0.0024 | 0.0013 | 0.0013 |
Echinococcus granulosus | FK506 binding protein 2 | 0.019 | 0.1213 | 0.1213 |
Echinococcus granulosus | glutamate receptor 4 | 0.0042 | 0.0141 | 0.0141 |
Trypanosoma brucei | TPR-repeat-containing chaperone protein DNAJ, putative | 0.0028 | 0.0043 | 0.0043 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase, putative | 0.019 | 0.1213 | 0.1234 |
Loa Loa (eye worm) | aspartyl protease 6 | 0.0119 | 0.0701 | 0.0713 |
Toxoplasma gondii | peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein | 0.019 | 0.1213 | 0.3481 |
Echinococcus granulosus | glutamate receptor 2 | 0.0062 | 0.0288 | 0.0288 |
Trypanosoma cruzi | serine/threonine protein phosphatase type 5, putative | 0.0024 | 0.0013 | 0.0013 |
Schistosoma mansoni | ATP-binding cassette transporter | 0.0025 | 0.0018 | 0.0018 |
Onchocerca volvulus | 0.0194 | 0.1242 | 1 | |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0024 | 0.0013 | 0.0013 |
Leishmania major | peptidylprolyl isomerase-like protein | 0.1383 | 0.9825 | 1 |
Trypanosoma brucei | stress-inducible protein STI1-like, putative | 0.0024 | 0.0013 | 0.0014 |
Trypanosoma brucei | FKBP-type peptidylprolyl cis-trans isomerase, putative | 0.019 | 0.1213 | 0.1234 |
Trypanosoma cruzi | macrophage infectivity potentiator, precursor, putative | 0.019 | 0.1213 | 0.1234 |
Plasmodium falciparum | peptidyl-prolyl cis-trans isomerase, putative | 0.0024 | 0.0013 | 0.0013 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0024 | 0.0013 | 0.0014 |
Trypanosoma cruzi | FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative | 0.1383 | 0.9825 | 1 |
Loa Loa (eye worm) | TPR Domain containing protein | 0.0024 | 0.0013 | 0.0013 |
Brugia malayi | TPR Domain containing protein | 0.0024 | 0.0013 | 0.0013 |
Onchocerca volvulus | Tetratricopeptide repeat protein 5 homolog | 0.0024 | 0.0013 | 0.0106 |
Trichomonas vaginalis | Clan AA, family A1, cathepsin D-like aspartic peptidase | 0.0505 | 0.3485 | 0.3547 |
Treponema pallidum | peptidyl-prolyl cis-trans isomerase, FKBP-type (slyD) | 0.019 | 0.1213 | 0.1223 |
Trichomonas vaginalis | fk506-binding protein, putative | 0.019 | 0.1213 | 0.1234 |
Brugia malayi | aspartic protease BmAsp-1, identical | 0.0119 | 0.0701 | 0.0711 |
Echinococcus granulosus | glutamate receptor ionotrophic AMPA 3 | 0.0071 | 0.0354 | 0.0354 |
Trypanosoma brucei | macrophage infectivity potentiator, precursor, putative | 0.019 | 0.1213 | 0.1234 |
Leishmania major | hypothetical protein, conserved | 0.0024 | 0.0013 | 0.0013 |
Trypanosoma cruzi | stress-inducible protein STI1-like, putative | 0.0024 | 0.0013 | 0.0014 |
Echinococcus granulosus | Tetratricopeptide repeat protein 1 | 0.0024 | 0.0013 | 0.0013 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0141 | 0.0143 |
Echinococcus multilocularis | peptidyl prolyl cis trans isomerase FKBP4 | 0.1217 | 0.8626 | 0.8626 |
Loa Loa (eye worm) | glutamate receptor 2 | 0.0025 | 0.0018 | 0.0018 |
Echinococcus multilocularis | glutamate receptor, ionotrophic, AMPA 3 | 0.0071 | 0.0354 | 0.0354 |
Trypanosoma brucei | serine/threonine protein phosphatase 5 | 0.0024 | 0.0013 | 0.0013 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.003 | 0.0052 | 0.0052 |
Brugia malayi | FKBP-type peptidyl-prolyl cis-trans isomerase-59, BmFKBP59 | 0.1387 | 0.9855 | 1 |
Loa Loa (eye worm) | UDP-N-acetylglucosamine-peptide N-acetylglucosaminyltransferase | 0.0024 | 0.0013 | 0.0014 |
Plasmodium falciparum | plasmepsin IX | 0.0119 | 0.0701 | 0.0713 |
Plasmodium falciparum | plasmepsin VII | 0.0119 | 0.0701 | 0.0713 |
Chlamydia trachomatis | peptidyl-prolyl cis-trans isomerase | 0.019 | 0.1213 | 0.5 |
Entamoeba histolytica | TPR repeat protein | 0.0024 | 0.0013 | 0.0013 |
Onchocerca volvulus | 0.019 | 0.1213 | 0.9763 | |
Loa Loa (eye worm) | FKBP-type peptidyl-prolyl cis-trans isomerase-30 | 0.019 | 0.1213 | 0.1234 |
Trichomonas vaginalis | conserved hypothetical protein | 0.019 | 0.1213 | 0.1234 |
Plasmodium vivax | aspartyl protease, putative | 0.0119 | 0.0701 | 0.0713 |
Trichomonas vaginalis | peptidylprolyl isomerase, putative | 0.1383 | 0.9825 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0141 | 0.0143 |
Trichomonas vaginalis | chaperone binding protein, putative | 0.0024 | 0.0013 | 0.0014 |
Echinococcus multilocularis | cathepsin d (lysosomal aspartyl protease) | 0.0505 | 0.3485 | 0.3485 |
Schistosoma mansoni | DNAj homolog subfamily C member | 0.0028 | 0.0043 | 0.0043 |
Entamoeba histolytica | peptidyl-prolyl cis-trans isomerase, FKBP-type , putative | 0.019 | 0.1213 | 0.1213 |
Plasmodium falciparum | plasmepsin VI | 0.0505 | 0.3485 | 0.3547 |
Leishmania major | fk506-binding protein 1-like protein | 0.1383 | 0.9825 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.019 | 0.1213 | 0.1234 |
Trichomonas vaginalis | chaperone binding protein, putative | 0.0024 | 0.0013 | 0.0014 |
Plasmodium vivax | plasmepsin IV, putative | 0.0505 | 0.3485 | 0.3547 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase, putative | 0.1383 | 0.9825 | 1 |
Leishmania major | stress-induced protein sti1 | 0.0024 | 0.0013 | 0.0013 |
Trypanosoma brucei | peptidyl-prolyl cis-trans isomerase, putative | 0.1383 | 0.9825 | 1 |
Brugia malayi | Glutamate receptor 1 precursor | 0.0067 | 0.032 | 0.0325 |
Trichomonas vaginalis | fk506-binding protein, putative | 0.019 | 0.1213 | 0.1234 |
Trypanosoma cruzi | N-acetyltransferase subunit Nat1, putative | 0.0024 | 0.0013 | 0.0013 |
Toxoplasma gondii | aspartyl protease ASP1 | 0.0505 | 0.3485 | 1 |
Schistosoma mansoni | immunophilin | 0.1407 | 1 | 1 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.003 | 0.0052 | 0.0052 |
Loa Loa (eye worm) | FKBP-type peptidyl-prolyl cis-trans isomerase-33 | 0.019 | 0.1213 | 0.1234 |
Trypanosoma cruzi | FKBP-type peptidylprolyl cis-trans isomerase, putative | 0.019 | 0.1213 | 0.1234 |
Plasmodium falciparum | plasmepsin X | 0.0119 | 0.0701 | 0.0713 |
Echinococcus granulosus | glutamate NMDA receptor subunit | 0.0025 | 0.0018 | 0.0018 |
Trypanosoma brucei | FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative | 0.1383 | 0.9825 | 1 |
Entamoeba histolytica | hypothetical protein, conserved domain containing | 0.0024 | 0.0013 | 0.0013 |
Plasmodium vivax | aspartyl proteinase, putative | 0.0119 | 0.0701 | 0.0713 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0024 | 0.0013 | 0.0014 |
Trypanosoma brucei | stress-inducible protein STI1-like, putative | 0.0024 | 0.0013 | 0.0014 |
Toxoplasma gondii | O-linked N-acetylglucosamine transferase | 0.0024 | 0.0013 | 0.0038 |
Toxoplasma gondii | peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein | 0.019 | 0.1213 | 0.3481 |
Trypanosoma brucei | peptidyl-prolyl cis-trans isomerase, putative | 0.019 | 0.1213 | 0.1234 |
Echinococcus granulosus | cathepsin d lysosomal aspartyl protease | 0.0505 | 0.3485 | 0.3485 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0119 | 0.0701 | 0.0701 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0024 | 0.0013 | 0.0013 |
Plasmodium vivax | peptidyl-prolyl cis-trans isomerase, putative | 0.0024 | 0.0013 | 0.0013 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.003 | 0.0052 | 0.0052 |
Toxoplasma gondii | eukaryotic aspartyl protease superfamily protein | 0.0119 | 0.0701 | 0.201 |
Loa Loa (eye worm) | TPR Domain containing protein | 0.0024 | 0.0013 | 0.0014 |
Giardia lamblia | FKBP-type peptidyl-prolyl cis-trans isomerase | 0.019 | 0.1213 | 0.1223 |
Plasmodium vivax | peptidyl-prolyl cis-trans isomerase, putative | 0.019 | 0.1213 | 0.1234 |
Trypanosoma brucei | stress-induced protein sti1, putative | 0.0024 | 0.0013 | 0.0014 |
Trypanosoma cruzi | N-acetyltransferase subunit Nat1, putative | 0.0024 | 0.0013 | 0.0013 |
Loa Loa (eye worm) | hypothetical protein | 0.1197 | 0.8481 | 0.8631 |
Onchocerca volvulus | 0.0119 | 0.0701 | 0.5639 | |
Plasmodium falciparum | plasmepsin V | 0.0119 | 0.0701 | 0.0713 |
Echinococcus granulosus | glutamate receptor 1 | 0.0042 | 0.0141 | 0.0141 |
Onchocerca volvulus | 0.0119 | 0.0701 | 0.5639 | |
Schistosoma mansoni | heat shock protein 70 | 0.0024 | 0.0013 | 0.0013 |
Echinococcus multilocularis | 0.019 | 0.1213 | 0.1213 | |
Echinococcus granulosus | stress induced phosphoprotein 1 | 0.0028 | 0.0043 | 0.0043 |
Echinococcus multilocularis | peptidyl prolyl cis trans isomerase FKBP4 | 0.1407 | 1 | 1 |
Onchocerca volvulus | Kinesin light chain homolog | 0.0024 | 0.0013 | 0.0106 |
Entamoeba histolytica | peptidyl-prolyl cis-trans isomerase, FKBP-type, putative | 0.1407 | 1 | 1 |
Trichomonas vaginalis | peptidylprolyl isomerase, putative | 0.1383 | 0.9825 | 1 |
Leishmania major | stress-inducible protein STI1 homolog | 0.0028 | 0.0043 | 0.0043 |
Giardia lamblia | FKBP-type peptidyl-prolyl cis-trans isomerase | 0.1383 | 0.9825 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0024 | 0.0013 | 0.0014 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0024 | 0.0013 | 0.0013 |
Loa Loa (eye worm) | FKBP5 protein | 0.1383 | 0.9825 | 1 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0119 | 0.0701 | 0.0701 |
Trypanosoma cruzi | small glutamine-rich tetratricopeptide repeat protein, putative | 0.0024 | 0.0013 | 0.0014 |
Plasmodium vivax | aspartyl protease, putative | 0.0119 | 0.0701 | 0.0713 |
Brugia malayi | Eukaryotic aspartyl protease family protein | 0.0119 | 0.0701 | 0.0711 |
Mycobacterium tuberculosis | Probable trigger factor (TF) protein Tig | 0.019 | 0.1213 | 0.5 |
Echinococcus granulosus | mitochondrial import receptor subunit tom34 | 0.0024 | 0.0013 | 0.0013 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0119 | 0.0701 | 0.0701 |
Trypanosoma brucei | stress-inducible protein STI1-like, putative | 0.0024 | 0.0013 | 0.0014 |
Trypanosoma brucei | hypothetical protein, conserved | 0.019 | 0.1213 | 0.1234 |
Loa Loa (eye worm) | aspartic protease BmAsp-2 | 0.0505 | 0.3485 | 0.3547 |
Schistosoma mansoni | cathepsin D (A01 family) | 0.0786 | 0.5512 | 0.5512 |
Schistosoma mansoni | immunophilin | 0.1407 | 1 | 1 |
Plasmodium falciparum | plasmepsin II | 0.0505 | 0.3485 | 0.3547 |
Plasmodium falciparum | peptidyl-prolyl cis-trans isomerase, putative | 0.019 | 0.1213 | 0.1234 |
Schistosoma mansoni | cathepsin D (A01 family) | 0.0786 | 0.5512 | 0.5512 |
Plasmodium vivax | 70 kDa peptidylprolyl isomerase, putative | 0.1383 | 0.9825 | 1 |
Entamoeba histolytica | peptidyl-prolyl cis-trans isomerase, FKBP-type , putative | 0.1407 | 1 | 1 |
Brugia malayi | FKBP-type peptidyl-prolyl cis-trans isomerase-30, BmFKBP-30 | 0.019 | 0.1213 | 0.1231 |
Leishmania major | hypothetical protein, conserved | 0.0028 | 0.0043 | 0.0044 |
Schistosoma mansoni | immunophilin | 0.1217 | 0.8626 | 0.8626 |
Loa Loa (eye worm) | FKBP-type peptidyl-prolyl cis-trans isomerase-13 | 0.019 | 0.1213 | 0.1234 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.003 | 0.0052 | 0.0052 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0119 | 0.0701 | 0.0701 |
Trichomonas vaginalis | fk506 binding protein, putative | 0.019 | 0.1213 | 0.1234 |
Loa Loa (eye worm) | hypothetical protein | 0.0505 | 0.3485 | 0.3547 |
Brugia malayi | FKBP-type peptidyl-prolyl cis-trans isomerase-12, BmFKBP-12 | 0.1383 | 0.9825 | 0.997 |
Leishmania major | peptidyl-prolyl cis-trans isomerase, putative | 0.019 | 0.1213 | 0.1234 |
Schistosoma mansoni | glutamate receptor NMDA | 0.003 | 0.0052 | 0.0052 |
Loa Loa (eye worm) | TPR domain-containing protein | 0.0024 | 0.0013 | 0.0014 |
Echinococcus granulosus | peptidyl prolyl cis trans isomerase FKBP1A | 0.1383 | 0.9825 | 0.9825 |
Echinococcus multilocularis | stress induced phosphoprotein 1 | 0.0028 | 0.0043 | 0.0043 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0013 | 0.0013 |
Plasmodium falciparum | peptidyl-prolyl cis-trans isomerase FKBP35 | 0.1383 | 0.9825 | 1 |
Loa Loa (eye worm) | FKBP-type peptidyl-prolyl cis-trans isomerase-12 | 0.1383 | 0.9825 | 1 |
Echinococcus multilocularis | STIP1 y and U box containing protein 1 | 0.0024 | 0.0013 | 0.0013 |
Echinococcus granulosus | glutamate receptor 2 | 0.0071 | 0.0354 | 0.0354 |
Echinococcus granulosus | O glycosyltransferase | 0.0024 | 0.0013 | 0.0013 |
Onchocerca volvulus | 0.0024 | 0.0013 | 0.0106 | |
Toxoplasma gondii | tetratricopeptide repeat domain containing protein | 0.0024 | 0.0013 | 0.0038 |
Leishmania major | peptidyl-prolyl cis-trans isomerase, macrophage infectivity potentiator precursor, putative | 0.019 | 0.1213 | 0.1234 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0024 | 0.0013 | 0.0013 |
Trypanosoma brucei | small glutamine-rich tetratricopeptide repeat protein, putative | 0.0024 | 0.0013 | 0.0014 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase, putative | 0.1383 | 0.9825 | 1 |
Onchocerca volvulus | 0.0028 | 0.0043 | 0.0345 | |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0043 | 0.0043 |
Entamoeba histolytica | TPR repeat protein | 0.0024 | 0.0013 | 0.0013 |
Echinococcus multilocularis | FK506 binding protein 8, 38 kDa | 0.0215 | 0.1388 | 0.1388 |
Trichomonas vaginalis | chaperone binding protein, putative | 0.0024 | 0.0013 | 0.0013 |
Brugia malayi | TPR Domain containing protein | 0.0024 | 0.0013 | 0.0014 |
Plasmodium vivax | aspartyl protease, putative | 0.0119 | 0.0701 | 0.0713 |
Brugia malayi | hypothetical protein | 0.0119 | 0.0701 | 0.0711 |
Schistosoma mansoni | glutamate receptor kainate | 0.0025 | 0.0018 | 0.0018 |
Plasmodium vivax | Hsp70/Hsp90 organizing protein, putative | 0.0024 | 0.0013 | 0.0014 |
Trypanosoma cruzi | serine/threonine protein phosphatase type 5, putative | 0.0024 | 0.0013 | 0.0013 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (functional) | = 84.4 % | Vasorelaxant activity against KCl-induced contraction in Wistar rat aorta at 10 ug/ml | ChEMBL. | 17547457 |
IC50 (ADMET) | > 150 uM | Cytotoxicity against human HeLa cells by MTT method | ChEMBL. | 17547457 |
IC50 (ADMET) | > 150 uM | Cytotoxicity against human HeLa cells by MTT method | ChEMBL. | 17547457 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.