Detailed information for compound 540610

Basic information

Technical information
  • TDR Targets ID: 540610
  • Name: dibutoxy(iodomethyl)borane
  • MW: 297.969 | Formula: C9H20BIO2
  • H donors: 0 H acceptors: 0 LogP: 3.84 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: ICB(OCCCC)OCCCC
  • InChi: 1S/C9H20BIO2/c1-3-5-7-12-10(9-11)13-8-6-4-2/h3-9H2,1-2H3
  • InChiKey: JTBKQQJNWZOKCS-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • dibutyl iodomethaneboronate
  • dibutoxy-(iodomethyl)borane
  • 13251-29-1
  • NSC 150868
  • NSC150868
  • Boronic acid, (iodomethyl)-, dibutyl ester

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0036 0.0378 0.0401
Loa Loa (eye worm) hypothetical protein 0.0016 0.001 0.0008
Loa Loa (eye worm) hypothetical protein 0.0036 0.0378 0.0401
Echinococcus granulosus TRP transient receptor potential channel 0.0079 0.1221 0.1219
Trypanosoma brucei glucose transporter, putative 0.0036 0.0389 0.8137
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0036 0.0378 0.0376
Schistosoma mansoni glucose transporter 0.0016 0.001 0.0008
Loa Loa (eye worm) hypothetical protein 0.007 0.1043 0.1111
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0298 0.5423 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0036 0.0378 0.0376
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0035 0.0367 0.0365
Trypanosoma cruzi hexose transporter, putative 0.0016 0.001 0.0158
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0387 0.728
Loa Loa (eye worm) hypothetical protein 0.0016 0.001 0.0008
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0035 0.0367 0.0514
Schistosoma mansoni sugar transporter 0.0016 0.001 0.0008
Echinococcus multilocularis rhodopsin orphan GPCR 0.0036 0.0378 0.0376
Schistosoma mansoni alpha-glucosidase 0.0137 0.2324 0.2323
Schistosoma mansoni protein kinase 0.0036 0.0381 0.0378
Brugia malayi hypothetical protein 0.0025 0.0168 0.0179
Loa Loa (eye worm) hypothetical protein 0.0016 0.001 0.0008
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0133 0.0132
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0236 0.0388
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0146 0.2493 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0298 0.5423 0.578
Loa Loa (eye worm) hypothetical protein 0.0036 0.0378 0.0401
Schistosoma mansoni jumonji/arid domain-containing protein 0.006 0.0847 0.0845
Trichomonas vaginalis glucosylceramidase, putative 0.033 0.6046 0.6446
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0036 0.0378 0.0376
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0036 0.0378 0.0376
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0022 0.0119 0.0442
Leishmania major protein kinase, putative 0.0022 0.0123 0.228
Brugia malayi Dopamine receptor 0.0036 0.0378 0.0404
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0036 0.0378 0.0376
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0093 0.1903
Loa Loa (eye worm) hypothetical protein 0.0036 0.0378 0.0401
Schistosoma mansoni biogenic amine receptor 0.0036 0.0378 0.0376
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0387 0.8079
Trypanosoma cruzi cytochrome P450, putative 0.0019 0.0058 0.1168
Loa Loa (eye worm) hypothetical protein 0.0036 0.0378 0.0401
Loa Loa (eye worm) hypothetical protein 0.0018 0.004 0.004
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0298 0.5423 0.578
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0035 0.0373 0.0395
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0373 0.0525
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0036 0.0378 0.0376
Trypanosoma cruzi cytochrome P450, putative 0.0019 0.0058 0.1168
Schistosoma mansoni hypothetical protein 0.0536 1 1
Brugia malayi major facilitator superfamily protein 0.0016 0.001 0.001
Echinococcus granulosus RUN 0.0019 0.0064 0.0062
Loa Loa (eye worm) G-protein coupled receptor 0.0036 0.0378 0.0401
Onchocerca volvulus 0.0036 0.0378 0.0611
Entamoeba histolytica hypothetical protein 0.0035 0.0369 0.0519
Schistosoma mansoni Smad4 0.0018 0.0034 0.0031
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.002 0.008 0.1631
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0022 0.0119 0.0164
Echinococcus granulosus smad 0.0018 0.0034 0.0031
Trypanosoma brucei THT1 - hexose transporter, putative 0.0036 0.0389 0.8137
Schistosoma mansoni alpha glucosidase 0.0035 0.0373 0.0371
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0093 0.1903
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.002 0.008 0.147
Brugia malayi RE15519p 0.0036 0.0378 0.0404
Echinococcus granulosus solute carrier family 22 0.0016 0.001 0.0008
Echinococcus multilocularis g-protein coupled receptor 0.0036 0.0378 0.0376
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0041 0.0478 1
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0236 0.0233
Schistosoma mansoni smad 0.0018 0.0034 0.0031
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0093 0.0091
Schistosoma mansoni biogenic amine receptor 0.0036 0.0378 0.0376
Onchocerca volvulus 0.0092 0.1462 0.2405
Echinococcus granulosus neuropeptides capa receptor 0.0036 0.0378 0.0376
Echinococcus multilocularis lysine specific demethylase 5A 0.006 0.0847 0.0845
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0093 0.0098
Schistosoma mansoni amine GPCR 0.0036 0.0378 0.0376
Echinococcus granulosus hypothetical protein 0.0036 0.0378 0.0376
Brugia malayi hypothetical protein 0.0016 0.001 0.001
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0068 0.0999 0.0997
Brugia malayi jmjC domain containing protein 0.0016 0.0002 0.0002
Trichomonas vaginalis glucosylceramidase, putative 0.033 0.6046 0.6446
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0036 0.0378 0.0376
Loa Loa (eye worm) hypothetical protein 0.0185 0.3245 0.346
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.03 0.5467 0.583
Schistosoma mansoni sugar transporter 0.0016 0.001 0.0008
Trypanosoma cruzi sugar transporter, putative 0.0016 0.001 0.0158
Echinococcus multilocularis RUN 0.0019 0.0064 0.0062
Echinococcus granulosus aryl hydrocarbon receptor 0.0038 0.0425 0.0423
Brugia malayi hypothetical protein 0.0035 0.0369 0.0394
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.006 0.0847 0.0845
Trypanosoma brucei glucose transporter, putative 0.0036 0.0389 0.8137
Loa Loa (eye worm) hypothetical protein 0.0036 0.0378 0.0401
Echinococcus granulosus tumor protein p63 0.0329 0.6024 0.6023
Loa Loa (eye worm) hypothetical protein 0.0028 0.0241 0.0255
Trichomonas vaginalis conserved hypothetical protein 0.002 0.008 0.0075
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0036 0.0378 0.0611
Brugia malayi jmjC domain containing protein 0.0016 0.0002 0.0002
Loa Loa (eye worm) MH2 domain-containing protein 0.0259 0.4667 0.4977
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0214 0.3816 0.4071
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0035 0.0367 0.1189
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0036 0.0381 0.0378
Schistosoma mansoni smad1 5 8 and 0.0018 0.0034 0.0031
Trypanosoma brucei cytochrome P450, putative 0.0019 0.0058 0.1168
Leishmania major protein kinase, putative 0.0036 0.0381 0.7166
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0115 0.1904 0.1902
Loa Loa (eye worm) hypothetical protein 0.0036 0.0378 0.0401
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0093 0.0098
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0036 0.0378 0.0401
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0036 0.0378 0.0376
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0036 0.0378 0.0376
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0036 0.0378 0.0376
Onchocerca volvulus 0.0036 0.0378 0.0611
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0115 0.1904 0.1902
Schistosoma mansoni polycystin 1-related 0.0019 0.0064 0.0062
Echinococcus multilocularis short transient receptor potential channel 6 0.0139 0.2374 0.2372
Schistosoma mansoni lipoxygenase 0.008 0.1239 0.1237
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0036 0.0378 0.0404
Schistosoma mansoni protein kinase 0.0036 0.0381 0.0378
Loa Loa (eye worm) hypothetical protein 0.0016 0.001 0.0008
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0035 0.0367 0.0365
Brugia malayi hypothetical protein 0.0036 0.0378 0.0404
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0373 0.0388
Loa Loa (eye worm) hypothetical protein 0.0036 0.0378 0.0401
Trypanosoma cruzi hexose transporter, putative 0.002 0.0075 0.1519
Brugia malayi neuropeptide F receptor 0.0036 0.0378 0.0404
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0022 0.0119 0.0442
Loa Loa (eye worm) hypothetical protein 0.0026 0.0195 0.0205
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0116 0.1934 0.1933
Echinococcus granulosus short transient receptor potential channel 6 0.0139 0.2376 0.2375
Toxoplasma gondii lysine-tRNA ligase 0.0026 0.0195 0.032
Brugia malayi hypothetical protein 0.0036 0.0378 0.0404
Brugia malayi Doublecortin family protein 0.0019 0.0064 0.0068
Schistosoma mansoni neuropeptide f receptor 76f 0.0036 0.0378 0.0376
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0146 0.2493 1
Trypanosoma cruzi hexose transporter, putative 0.0036 0.0389 0.8137
Onchocerca volvulus Neuropeptide F receptor homolog 0.0036 0.0378 0.0611
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0026 0.0195 0.4046
Toxoplasma gondii protein kinase, putative 0.0329 0.6022 1
Schistosoma mansoni alpha-glucosidase 0.0137 0.2324 0.2323
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0036 0.0381 0.0404
Brugia malayi jmjC domain containing protein 0.0016 0.0002 0.0002
Echinococcus multilocularis snurportin 1 0.03 0.5467 0.5466
Echinococcus granulosus solute carrier family 22 0.0016 0.001 0.0008
Schistosoma mansoni hypothetical protein 0.0068 0.0999 0.0997
Schistosoma mansoni histamine h1 receptor 0.0036 0.0378 0.0376
Echinococcus granulosus synaptic vesicle 2 protein 0.0016 0.001 0.0008
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0387 0.8079
Loa Loa (eye worm) inositol-1 0.0036 0.0387 0.041
Schistosoma mansoni single-minded 0.0055 0.0754 0.0752
Leishmania major importin beta-1 subunit, putative 0.0023 0.0133 0.2482
Loa Loa (eye worm) hypothetical protein 0.0036 0.0378 0.0401
Echinococcus multilocularis dro:myosuppressin receptor 0.0036 0.0378 0.0376
Brugia malayi hypothetical protein 0.0036 0.0378 0.0404
Echinococcus multilocularis Smad4 0.0018 0.0034 0.0031
Trichomonas vaginalis glucosylceramidase, putative 0.0504 0.9374 1
Echinococcus granulosus neuropeptide FF receptor 2 0.0036 0.0378 0.0376
Loa Loa (eye worm) hypothetical protein 0.0035 0.0367 0.0389
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0016 0.001 0.0158
Loa Loa (eye worm) hypothetical protein 0.0048 0.0621 0.066
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0036 0.0378 0.0376
Onchocerca volvulus 0.0036 0.0378 0.0611
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0016 0.001 0.0008
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0133 0.0132
Loa Loa (eye worm) hypoxia-induced factor 1 0.0147 0.2515 0.2681
Loa Loa (eye worm) hypothetical protein 0.0016 0.001 0.0008
Loa Loa (eye worm) hypothetical protein 0.013 0.2196 0.2341
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0036 0.0381 0.0412
Trypanosoma cruzi hexose transporter, putative 0.0036 0.0389 0.8137
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0214 0.3816 0.407
Echinococcus granulosus importin subunit beta 1 0.0028 0.0236 0.0233
Schistosoma mansoni opsin-like receptor 0.0036 0.0378 0.0376
Onchocerca volvulus 0.0036 0.0378 0.0611
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0018 0.004 0.0043
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0035 0.0373 0.0615
Brugia malayi larval opioid receptor 0.0036 0.0378 0.0404
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0387 0.0402
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0064 0.0062
Echinococcus granulosus rhodopsin orphan GPCR 0.0036 0.0378 0.0376
Echinococcus granulosus snurportin 1 0.03 0.5467 0.5466
Loa Loa (eye worm) hypothetical protein 0.0036 0.0378 0.0401
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.002 0.008 0.0075
Brugia malayi hypothetical protein 0.0036 0.0378 0.0404
Echinococcus granulosus Smad4 0.0018 0.0034 0.0031
Loa Loa (eye worm) hypothetical protein 0.0214 0.3816 0.407
Schistosoma mansoni growth hormone secretagogue receptor 0.0036 0.0378 0.0376
Loa Loa (eye worm) cytochrome P450 family protein 0.0019 0.0058 0.0059
Echinococcus multilocularis rhodopsin orphan GPCR 0.0036 0.0378 0.0376
Trichomonas vaginalis glucosylceramidase, putative 0.0504 0.9374 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.0378 0.0401
Echinococcus multilocularis rhodopsin orphan GPCR 0.0036 0.0378 0.0376
Loa Loa (eye worm) MH2 domain-containing protein 0.0018 0.0034 0.0034
Brugia malayi Cytochrome P450 family protein 0.0019 0.0058 0.0062
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0236 0.4903
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0036 0.0378 0.0376
Echinococcus granulosus sex peptide receptor 0.0036 0.0378 0.0376
Trichomonas vaginalis adenylate cyclase, putative 0.002 0.008 0.0075
Brugia malayi hypothetical protein 0.0036 0.0378 0.0404
Leishmania major myo-inositol/proton symporter (MIT) 0.0016 0.001 0.0143
Trypanosoma cruzi glucose transporter, putative 0.0016 0.001 0.0158
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0116 0.1934 0.1933
Leishmania major alpha glucosidase II subunit, putative 0.0035 0.0373 0.7016
Echinococcus multilocularis neuropeptide FF receptor 2 0.0036 0.0378 0.0376
Schistosoma mansoni amine GPCR 0.0036 0.0378 0.0376
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0026 0.0195 0.0745
Echinococcus multilocularis General substrate transporter 0.01 0.162 0.1618
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0036 0.0378 0.0376
Schistosoma mansoni hypothetical protein 0.03 0.5467 0.5466
Echinococcus multilocularis transient receptor potential gamma protein 0.021 0.3722 0.3721
Trichomonas vaginalis guanylate cyclase, putative 0.002 0.008 0.0075
Brugia malayi Major Facilitator Superfamily protein 0.0016 0.001 0.001
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0236 0.4903
Plasmodium vivax hexose transporter 0.0116 0.1934 0.2101
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0064 0.0062
Trichomonas vaginalis ran, putative 0.0021 0.0093 0.0089
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0116 0.1934 0.1933
Brugia malayi G-protein coupled receptor 0.0036 0.0378 0.0404
Brugia malayi Smad1 0.0018 0.0034 0.0036
Echinococcus granulosus short transient receptor potential channel 6 0.0139 0.2374 0.2372
Plasmodium vivax lysine--tRNA ligase, putative 0.0026 0.0195 0.0209
Loa Loa (eye worm) hypothetical protein 0.0036 0.0378 0.0401
Trichomonas vaginalis glucosylceramidase, putative 0.033 0.6046 0.6446
Trypanosoma brucei glucose transporter, putative 0.0036 0.0389 0.8137
Plasmodium falciparum mitogen-activated protein kinase 2 0.0188 0.3314 0.36
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0036 0.0378 0.0376
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0036 0.0378 0.0376
Loa Loa (eye worm) hypothetical protein 0.0068 0.0999 0.1063
Echinococcus granulosus rhodopsin orphan GPCR 0.0036 0.0378 0.0376
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0298 0.5423 0.578
Onchocerca volvulus 0.0019 0.0064 0.009
Onchocerca volvulus 0.0038 0.0425 0.0688
Echinococcus multilocularis neuropeptides capa receptor 0.0036 0.0378 0.0376
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0036 0.0378 0.0376
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0387 0.0402
Loa Loa (eye worm) sugar transporter 0.0016 0.001 0.0008
Onchocerca volvulus 0.0036 0.0378 0.0611
Brugia malayi HSF-type DNA-binding domain containing protein 0.0097 0.1554 0.1658
Schistosoma mansoni aryl hydrocarbon receptor 0.0055 0.0754 0.0752
Echinococcus granulosus biogenic amine 5HT receptor 0.0278 0.5041 0.504
Loa Loa (eye worm) hypothetical protein 0.0036 0.0378 0.0401
Loa Loa (eye worm) hypothetical protein 0.0028 0.0236 0.0249
Onchocerca volvulus 0.0036 0.0378 0.0611
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0133 0.2754
Echinococcus multilocularis neuropeptide Y receptor 0.0036 0.0378 0.0376
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0036 0.0381 0.0406
Loa Loa (eye worm) Smad1 0.0018 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0278 0.5041 0.5376
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.002 0.008 0.0075
Trichomonas vaginalis glucosylceramidase, putative 0.0504 0.9374 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0036 0.0378 0.0376
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.002 0.008 0.0078
Echinococcus granulosus serotonin receptor 0.0036 0.0378 0.0376
Echinococcus multilocularis fmrfamide receptor 0.0036 0.0378 0.0376
Toxoplasma gondii sugar transporter ST3 0.0016 0.001 0.0013
Schistosoma mansoni rab6-interacting 0.0019 0.0064 0.0062
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0022 0.0123 0.2531
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0019 0.0058 0.0194
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0387 0.0402
Echinococcus granulosus alpha 1A adrenergic receptor 0.0036 0.0378 0.0376
Schistosoma mansoni jumonji/arid domain-containing protein 0.006 0.0847 0.0845
Brugia malayi hypothetical protein 0.0018 0.004 0.0043
Echinococcus granulosus g protein coupled receptor 0.0036 0.0378 0.0376
Echinococcus multilocularis lysosomal alpha glucosidase 0.0159 0.275 0.2748
Loa Loa (eye worm) hypothetical protein 0.0035 0.0367 0.0389
Echinococcus granulosus neuropeptide receptor 0.0036 0.0378 0.0376
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0036 0.0378 0.0376
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0036 0.0378 0.0376
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0369 0.0367
Echinococcus multilocularis lysosomal alpha glucosidase 0.0159 0.275 0.2748
Brugia malayi jmjC domain containing protein 0.0016 0.0002 0.0002
Schistosoma mansoni jumonji domain containing protein 0.006 0.0847 0.0845
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0036 0.0378 0.0376
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0188 0.3314 0.5501
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0036 0.0381 0.0378
Leishmania major glucose transporter, lmgt2 0.0036 0.0389 0.7332
Schistosoma mansoni opsin-like receptor 0.0036 0.0378 0.0376
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0072 0.1074 0.1072
Echinococcus multilocularis transfer RNA-Lys 0.0035 0.0369 0.0367
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0018 0.004 0.004
Echinococcus granulosus neuropeptide s receptor 0.0036 0.0378 0.0376
Brugia malayi G protein-coupled receptor 0.0036 0.0378 0.0404
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0036 0.0378 0.0376
Schistosoma mansoni hypothetical protein 0.0068 0.0999 0.0997
Trichomonas vaginalis conserved hypothetical protein 0.002 0.008 0.0075
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0373 0.0388
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0036 0.0378 0.0404
Loa Loa (eye worm) hypothetical protein 0.0036 0.0378 0.0401
Schistosoma mansoni transient receptor potential channel 0.021 0.3722 0.3721
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0116 0.1934 0.1933
Echinococcus granulosus rhodopsin orphan GPCR 0.0036 0.0378 0.0376
Loa Loa (eye worm) hypothetical protein 0.0016 0.001 0.0008
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0168 0.3473
Schistosoma mansoni rab6-interacting 0.0019 0.0064 0.0062
Loa Loa (eye worm) cytochrome P450 family protein 0.0019 0.0058 0.0059
Echinococcus multilocularis serotonin receptor 0.0278 0.5041 0.504
Echinococcus multilocularis smad 0.0018 0.0034 0.0031
Echinococcus multilocularis geminin 0.0536 1 1
Trichomonas vaginalis glucosylceramidase, putative 0.0504 0.9374 1
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0036 0.0381 0.0378
Schistosoma mansoni biogenic amine (5HT) receptor 0.0278 0.5041 0.504
Brugia malayi hypothetical protein 0.0254 0.4575 0.488
Loa Loa (eye worm) hypothetical protein 0.0016 0.001 0.0008
Loa Loa (eye worm) hypothetical protein 0.0036 0.0378 0.0401
Trypanosoma brucei THT1 - hexose transporter, putative 0.0036 0.0389 0.8137
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0387 0.0551
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0298 0.5423 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.0378 0.0401
Loa Loa (eye worm) hypothetical protein 0.0016 0.001 0.0008
Trypanosoma brucei THT1 - hexose transporter, putative 0.0036 0.0389 0.8137
Trichomonas vaginalis sugar transporter, putative 0.0036 0.0389 0.0405
Schistosoma mansoni smad1 5 8 and 0.0018 0.0034 0.0031
Trichomonas vaginalis conserved hypothetical protein 0.0116 0.1934 0.2055
Plasmodium falciparum calcium-dependent protein kinase 1 0.0036 0.0381 0.0412
Echinococcus granulosus neutral alpha glucosidase AB 0.0035 0.0373 0.0371
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0036 0.0378 0.0376
Brugia malayi hypothetical protein 0.0036 0.0378 0.0404
Leishmania major hypothetical protein, conserved 0.0025 0.0168 0.313
Loa Loa (eye worm) hypothetical protein 0.0036 0.0378 0.0401
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0036 0.0381 0.0378
Echinococcus multilocularis sodium channel protein 0.0043 0.053 0.0528
Loa Loa (eye worm) hypothetical protein 0.021 0.3722 0.3969
Trypanosoma cruzi hexose transporter 0.0036 0.0389 0.8137
Loa Loa (eye worm) jmjC domain-containing protein 0.006 0.0847 0.0902
Echinococcus multilocularis neuropeptides capa receptor 0.0036 0.0378 0.0376
Onchocerca volvulus 0.0036 0.0378 0.0611
Brugia malayi hypothetical protein 0.0036 0.0378 0.0404
Schistosoma mansoni survival motor neuron protein 0.0052 0.069 0.0688
Brugia malayi aryl hydrocarbon receptor AHR-1 0.0018 0.004 0.0043
Entamoeba histolytica hypothetical protein 0.0026 0.0195 0.0191
Brugia malayi hypothetical protein 0.0036 0.0378 0.0404
Trichomonas vaginalis glucosylceramidase, putative 0.033 0.6046 0.6446
Loa Loa (eye worm) hypothetical protein 0.0147 0.2512 0.2678
Loa Loa (eye worm) hypothetical protein 0.0036 0.0378 0.0401
Brugia malayi hypothetical protein 0.0036 0.0378 0.0404
Loa Loa (eye worm) major facilitator superfamily transporter 0.0016 0.001 0.0008
Echinococcus granulosus rhodopsin orphan GPCR 0.0036 0.0378 0.0376
Schistosoma mansoni glucose transport protein 0.0116 0.1934 0.1933
Schistosoma mansoni protein kinase 0.0036 0.0381 0.0378
Echinococcus multilocularis solute carrier family 22 0.0016 0.001 0.0008
Plasmodium falciparum calcium-dependent protein kinase 5 0.0036 0.0381 0.0412
Schistosoma mansoni hypothetical protein 0.0035 0.0369 0.0367
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0041 0.0478 0.9011
Echinococcus multilocularis solute carrier family 22 0.0016 0.001 0.0008
Brugia malayi hypothetical protein 0.0036 0.0378 0.0404
Echinococcus multilocularis rhodopsin orphan GPCR 0.0036 0.0378 0.0376
Schistosoma mansoni ran 0.0021 0.0093 0.0091
Trichomonas vaginalis glucose transporter, putative 0.0036 0.0389 0.0405
Schistosoma mansoni smad1 5 8 and 0.0018 0.0034 0.0031
Echinococcus granulosus neuropeptide Y receptor 0.0036 0.0378 0.0376
Loa Loa (eye worm) hypothetical protein 0.0018 0.004 0.004
Echinococcus multilocularis neuropeptide receptor 0.0036 0.0378 0.0376
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0023 0.0133 0.0132
Leishmania major protein kinase, putative 0.0022 0.0123 0.228
Schistosoma mansoni neuropeptide receptor 0.0036 0.0378 0.0376
Onchocerca volvulus 0.0036 0.0378 0.0611
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0373 0.0525
Loa Loa (eye worm) hypothetical protein 0.0036 0.0378 0.0401
Loa Loa (eye worm) hypothetical protein 0.0025 0.0168 0.0176
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0016 0.001 0.0008
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.002 0.008 0.1631
Echinococcus granulosus rhodopsin orphan GPCR 0.0036 0.0378 0.0376
Echinococcus granulosus survival motor neuron protein 1 0.0254 0.4575 0.4573
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0018 0.0034 0.0031
Echinococcus multilocularis solute carrier family 22 0.0016 0.001 0.0008
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0369 0.0367
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0373 0.0388
Trichomonas vaginalis guanylate cyclase, putative 0.002 0.008 0.0075
Brugia malayi neuropeptide F receptor 0.0036 0.0378 0.0404
Echinococcus multilocularis rhodopsin orphan GPCR 0.0036 0.0378 0.0376
Plasmodium vivax proline--tRNA ligase, putative 0.0041 0.0478 0.0517
Leishmania major cytochrome p450-like protein 0.0019 0.0058 0.1053
Echinococcus multilocularis rhodopsin orphan GPCR 0.0036 0.0378 0.0376
Brugia malayi Protein kinase domain containing protein 0.0016 0.0007 0.0007
Trypanosoma brucei glucose transporter 1E 0.0036 0.0389 0.8137
Brugia malayi hypothetical protein 0.0019 0.0064 0.0068
Schistosoma mansoni inositol monophosphatase 0.0036 0.0387 0.0385
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0041 0.0478 1
Loa Loa (eye worm) hypothetical protein 0.0254 0.4575 0.4879
Echinococcus granulosus allatostatin A receptor 0.0036 0.0378 0.0376
Loa Loa (eye worm) transcription factor SMAD2 0.0259 0.4667 0.4977
Echinococcus granulosus solute carrier family 22 0.0016 0.001 0.0008
Echinococcus multilocularis tumor protein p63 0.0329 0.6024 0.6023
Trichomonas vaginalis conserved hypothetical protein 0.002 0.008 0.0075
Echinococcus multilocularis allatostatin A receptor 0.0036 0.0378 0.0376
Plasmodium falciparum calcium-dependent protein kinase 2 0.0036 0.0381 0.0412
Loa Loa (eye worm) hypothetical protein 0.0036 0.0378 0.0401
Schistosoma mansoni hypothetical protein 0.0052 0.069 0.0688
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0621 0.0619
Schistosoma mansoni hypothetical protein 0.0147 0.2512 0.2511
Echinococcus granulosus peptide allatostatin:somatostatin 0.0036 0.0378 0.0376
Brugia malayi Cam kinase protein 1 0.0036 0.0381 0.0406
Brugia malayi hypothetical protein 0.0185 0.3245 0.3462
Toxoplasma gondii sugar transporter ST2 0.0016 0.001 0.0013
Echinococcus granulosus General substrate transporter 0.01 0.162 0.1618
Trichomonas vaginalis glucose transporter, putative 0.0036 0.0389 0.0405
Leishmania major glucose transporter, lmgt1 0.0036 0.0389 0.7332
Loa Loa (eye worm) hypothetical protein 0.0036 0.0378 0.0401
Loa Loa (eye worm) hypothetical protein 0.0036 0.0381 0.0404
Giardia lamblia Fructose-bisphosphate aldolase 0.0298 0.5423 1
Giardia lamblia Lysyl-tRNA synthetase 0.0026 0.0195 0.0342
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0298 0.5423 0.578
Loa Loa (eye worm) hypothetical protein 0.0036 0.0378 0.0401
Brugia malayi RNA, U transporter 1 0.008 0.1232 0.1315
Loa Loa (eye worm) hypothetical protein 0.0016 0.001 0.0008
Echinococcus granulosus mothers against decapentaplegic 5 0.0018 0.0034 0.0031
Brugia malayi Tachykinin-like peptides receptor 99D 0.0036 0.0378 0.0404
Echinococcus multilocularis rhodopsin orphan GPCR 0.0036 0.0378 0.0376
Echinococcus granulosus fmrfamide receptor 0.0036 0.0378 0.0376
Brugia malayi Transient-receptor-potential like protein 0.0079 0.1221 0.1303
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0036 0.0378 0.0404
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0036 0.0378 0.0376
Entamoeba histolytica heat shock transcription factor, putative 0.0097 0.1554 0.2742
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0298 0.5423 0.578
Brugia malayi Importin beta-1 subunit 0.0028 0.0236 0.0251
Brugia malayi Calcitonin receptor-like protein seb-1 0.0214 0.3816 0.4071
Echinococcus granulosus Polycystic kidney disease protein 0.0019 0.0064 0.0062
Onchocerca volvulus 0.0052 0.069 0.1127
Brugia malayi G-protein coupled receptor 0.0036 0.0378 0.0404
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0036 0.0378 0.0376
Onchocerca volvulus 0.0048 0.0621 0.1013
Loa Loa (eye worm) hypothetical protein 0.0018 0.004 0.004
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0036 0.0378 0.0376
Treponema pallidum fructose-bisphosphate aldolase 0.0298 0.5423 0.5
Echinococcus multilocularis somatostatin receptor 0.0036 0.0378 0.0376
Schistosoma mansoni ran 0.0021 0.0093 0.0091
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0032 0.0314 0.1226
Schistosoma mansoni amine GPCR 0.0036 0.0378 0.0376
Brugia malayi Glycosyl hydrolases family 31 protein 0.0159 0.275 0.2933
Loa Loa (eye worm) hypothetical protein 0.0016 0.001 0.0008
Echinococcus granulosus sodium channel protein 0.0043 0.053 0.0528
Brugia malayi AKH receptor 0.0036 0.0378 0.0404
Schistosoma mansoni hypothetical protein 0.0068 0.0999 0.0997
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0168 0.018
Entamoeba histolytica hypothetical protein 0.0035 0.0369 0.0519
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0387 0.8079
Entamoeba histolytica hypothetical protein 0.0035 0.0369 0.0519
Loa Loa (eye worm) hypothetical protein 0.0036 0.0378 0.0401
Brugia malayi MH2 domain containing protein 0.0259 0.4667 0.4978
Trichomonas vaginalis glucosylceramidase, putative 0.0504 0.9374 1
Echinococcus multilocularis Polycystic kidney disease protein 0.0019 0.0064 0.0062
Loa Loa (eye worm) hypothetical protein 0.0036 0.0378 0.0401
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0035 0.0367 0.0391
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0018 0.0034 0.0031
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0036 0.0381 0.7952
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0093 0.0099
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0168 0.0275
Plasmodium falciparum LCCL domain-containing protein 0.0019 0.0064 0.0067
Plasmodium vivax sugar transporter, putative 0.0016 0.001 0.0008
Echinococcus granulosus lysosomal alpha glucosidase 0.0159 0.275 0.2748
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0036 0.0378 0.0376
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0036 0.0378 0.0376
Brugia malayi Dopamine receptor protein 2 0.0036 0.0378 0.0404
Echinococcus multilocularis rhodopsin orphan GPCR 0.0036 0.0378 0.0376
Echinococcus granulosus g protein coupled receptor 0.0036 0.0378 0.0376
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0068 0.0999 0.0997
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0036 0.0378 0.0376
Mycobacterium ulcerans putative regulatory protein 0.0035 0.0369 0.1448
Schistosoma mansoni inositol monophosphatase 0.0036 0.0387 0.0385
Loa Loa (eye worm) doublecortin family protein 0.0019 0.0064 0.0066
Echinococcus granulosus 7TM GPCR rhodopsin 0.0036 0.0378 0.0376
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0093 0.0097
Loa Loa (eye worm) hypothetical protein 0.0036 0.0378 0.0401
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0146 0.2493 1
Loa Loa (eye worm) G-protein coupled receptor 0.0036 0.0378 0.0401
Echinococcus granulosus TGF beta signal transducer SmadC 0.0018 0.0034 0.0031
Leishmania major hypothetical protein, conserved 0.0016 0.001 0.0143
Echinococcus granulosus single minded 2 0.0035 0.0369 0.0367
Brugia malayi hypothetical protein 0.0018 0.004 0.0043
Chlamydia trachomatis lysine--tRNA ligase 0.0026 0.0195 1
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0036 0.0381 0.0404
Schistosoma mansoni hypothetical protein 0.0036 0.0378 0.0376
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0159 0.275 0.2932
Loa Loa (eye worm) CYP4Cod1 0.0019 0.0058 0.0059
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0036 0.0378 0.0376
Brugia malayi Cytochrome P450 family protein 0.0019 0.0058 0.0062
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0064 0.0062
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0168 0.018
Onchocerca volvulus 0.0036 0.0378 0.0611
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0036 0.0381 0.0412
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0036 0.0378 0.0401
Loa Loa (eye worm) hypothetical protein 0.0079 0.1221 0.1301
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0373 0.7786
Onchocerca volvulus 0.0036 0.0378 0.0611
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0036 0.0381 0.0629
Echinococcus multilocularis fmrfamide receptor 0.0036 0.0378 0.0376
Brugia malayi bHLH-PAS transcription factor 0.0035 0.0369 0.0394
Loa Loa (eye worm) hypothetical protein 0.0036 0.0378 0.0401
Loa Loa (eye worm) neuropeptide F receptor 0.0036 0.0378 0.0401
Loa Loa (eye worm) hypothetical protein 0.0036 0.0378 0.0401
Schistosoma mansoni importin beta-1 0.0028 0.0236 0.0233
Loa Loa (eye worm) hypothetical protein 0.0016 0.001 0.0008
Loa Loa (eye worm) hypothetical protein 0.0036 0.0378 0.0401
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0504 0.9374 1
Onchocerca volvulus 0.0036 0.0378 0.0611
Toxoplasma gondii facilitative glucose transporter GT1 0.0116 0.1934 0.321
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0504 0.9374 1
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0052 0.069 0.0736
Brugia malayi Sugar transporter family protein 0.0016 0.001 0.001
Echinococcus multilocularis lysyl tRNA synthetase 0.0026 0.0195 0.0193
Loa Loa (eye worm) hypothetical protein 0.0278 0.5041 0.5376
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0093 0.0091
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0043 0.053 0.0528
Echinococcus multilocularis GPCR, family 2 0.0068 0.0999 0.0997
Trichomonas vaginalis sugar transporter, putative 0.0036 0.0389 0.0405
Brugia malayi Melatonin receptor type 1A 0.0036 0.0378 0.0404
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0168 0.3473
Loa Loa (eye worm) hypothetical protein 0.0036 0.0378 0.0401
Trypanosoma brucei glucose transporter, putative 0.0036 0.0389 0.8137
Echinococcus granulosus biogenic amine 5HT receptor 0.0036 0.0378 0.0376
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0016 0.001 0.0008
Brugia malayi MH1 domain containing protein 0.0018 0.0034 0.0036
Schistosoma mansoni hypothetical protein 0.0036 0.0378 0.0376
Loa Loa (eye worm) latrophilin receptor protein 2 0.0068 0.0999 0.1063
Schistosoma mansoni hypothetical protein 0.0036 0.0378 0.0376
Schistosoma mansoni hypothetical protein 0.0019 0.0064 0.0062
Schistosoma mansoni lysyl-tRNA synthetase 0.0026 0.0195 0.0193
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0188 0.3314 0.36
Plasmodium falciparum proline--tRNA ligase 0.0041 0.0478 0.0517
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0036 0.0381 0.0378
Trypanosoma brucei glucose transporter, putative 0.0036 0.0389 0.8137
Onchocerca volvulus Protein cycle homolog 0.0018 0.004 0.005
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0116 0.1934 0.1933
Echinococcus granulosus neuropeptides capa receptor 0.0036 0.0378 0.0376
Schistosoma mansoni sugar transporter 0.0016 0.001 0.0008
Loa Loa (eye worm) hypothetical protein 0.0016 0.001 0.0008
Echinococcus multilocularis mothers against decapentaplegic 5 0.0018 0.0034 0.0031
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.002 0.008 0.0075
Schistosoma mansoni transient receptor potential channel 0.0139 0.2376 0.2375
Plasmodium falciparum lysine--tRNA ligase 0.0026 0.0195 0.0209
Onchocerca volvulus 0.0036 0.0378 0.0611
Trypanosoma brucei glucosidase, putative 0.0035 0.0373 0.7786
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0041 0.0478 1
Trypanosoma brucei sugar transporter, putative 0.0016 0.001 0.0158
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0022 0.0123 0.2531
Loa Loa (eye worm) hypothetical protein 0.0036 0.0378 0.0401
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0043 0.053 1
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.002 0.008 0.0075
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0036 0.0381 0.0378
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.002 0.008 0.0078
Loa Loa (eye worm) hypothetical protein 0.0019 0.0064 0.0066
Echinococcus granulosus tm gpcr rhodopsin 0.0036 0.0378 0.0376
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0036 0.0378 0.0376
Schistosoma mansoni hypothetical protein 0.0036 0.0378 0.0376
Echinococcus granulosus lysyl tRNA synthetase 0.0026 0.0195 0.0193
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0036 0.0378 0.0376
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0036 0.0378 0.0376
Echinococcus granulosus tm gpcr rhodopsin 0.0036 0.0378 0.0376
Echinococcus multilocularis neuropeptide Y receptor 0.0036 0.0378 0.0376
Echinococcus granulosus g protein coupled receptor 0.0036 0.0378 0.0376
Brugia malayi PAS domain containing protein 0.0055 0.0754 0.0805
Plasmodium falciparum calcium-dependent protein kinase 4 0.0036 0.0381 0.0412
Schistosoma mansoni biogenic amine (5HT) receptor 0.0036 0.0378 0.0376
Echinococcus granulosus Sugar transporter ERD6 protein 0.0016 0.001 0.0008
Brugia malayi Dopamine receptor protein 1 0.0036 0.0378 0.0404
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0068 0.0999 0.1066
Schistosoma mansoni alpha-1 adrenergic receptor 0.0036 0.0378 0.0376
Onchocerca volvulus 0.0019 0.0064 0.009
Loa Loa (eye worm) hypothetical protein 0.0019 0.0064 0.0066
Loa Loa (eye worm) MH1 domain-containing protein 0.0018 0.0034 0.0034
Brugia malayi hypoxia-induced factor 1 0.0147 0.2515 0.2683
Brugia malayi hypothetical protein 0.0016 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0016 0.001 0.0008
Loa Loa (eye worm) hypothetical protein 0.0036 0.0378 0.0401
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0036 0.0378 0.0376
Echinococcus multilocularis aryl hydrocarbon receptor 0.0038 0.0425 0.0423
Onchocerca volvulus 0.0036 0.0378 0.0611
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0133 0.0132
Trichomonas vaginalis glucosylceramidase, putative 0.033 0.6046 0.6446
Echinococcus granulosus rhodopsin orphan GPCR 0.0036 0.0378 0.0376
Brugia malayi follicle stimulating hormone receptor 0.0036 0.0378 0.0404
Loa Loa (eye worm) hypothetical protein 0.0016 0.001 0.0008
Giardia lamblia Prolyl-tRNA synthetase 0.0035 0.0367 0.066
Plasmodium falciparum calcium-dependent protein kinase 3 0.0036 0.0381 0.0412
Plasmodium vivax CDK-related protein kinase 6, putative 0.0494 0.92 1
Schistosoma mansoni neuropeptide receptor 0.0036 0.0378 0.0376
Echinococcus granulosus dro:myosuppressin receptor 0.0036 0.0378 0.0376
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0036 0.0378 0.0376
Trypanosoma brucei glucose transporter, putative 0.0036 0.0389 0.8137
Schistosoma mansoni hypothetical protein 0.0536 1 1
Brugia malayi Major Facilitator Superfamily protein 0.0016 0.001 0.001
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0041 0.0478 0.9011
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0026 0.0195 0.4046
Plasmodium falciparum protein kinase 7 0.0329 0.6022 0.6545
Loa Loa (eye worm) hypothetical protein 0.0036 0.0378 0.0401
Loa Loa (eye worm) neuropeptide F receptor 0.0036 0.0378 0.0401
Leishmania major glucose transporter, lmgt3 0.0036 0.0389 0.7332
Echinococcus granulosus neuropeptide receptor 0.0036 0.0378 0.0376
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0389 0.0405
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0036 0.0378 0.0376
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0093 0.0153
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0389 0.0405
Brugia malayi lysyl-tRNA synthetase 0.0026 0.0195 0.0208
Brugia malayi Inositol-1 0.0036 0.0387 0.0412
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0079 0.1221 0.1219
Schistosoma mansoni sugar transporter 0.0016 0.001 0.0008
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0116 0.1934 0.1933
Brugia malayi latrophilin 2 splice variant baaae 0.0147 0.2512 0.268
Brugia malayi Glycosyl hydrolases family 31 protein 0.0035 0.0373 0.0398
Loa Loa (eye worm) hypothetical protein 0.002 0.008 0.0083
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0022 0.0123 0.2531
Schistosoma mansoni glucose transport protein 0.0116 0.1934 0.1933
Onchocerca volvulus 0.0035 0.0369 0.0596
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0373 0.0388
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0036 0.0378 0.0376
Echinococcus multilocularis short transient receptor potential channel 6 0.0139 0.2376 0.2375
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0036 0.0381 0.0412
Loa Loa (eye worm) hypothetical protein 0.0036 0.0378 0.0401
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0022 0.0123 0.2531
Brugia malayi Serotonin receptor 0.0036 0.0378 0.0404
Brugia malayi sulfakinin receptor protein 0.0036 0.0378 0.0404
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0038 0.0425 0.0451
Echinococcus granulosus solute carrier family 22 0.0016 0.001 0.0008
Trichomonas vaginalis sugar transporter, putative 0.0036 0.0389 0.0405
Loa Loa (eye worm) hypothetical protein 0.0036 0.0378 0.0401
Echinococcus multilocularis neuropeptide s receptor 0.0036 0.0378 0.0376
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0036 0.0378 0.0401
Echinococcus multilocularis neuropeptide receptor 0.0036 0.0378 0.0376
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0093 0.015
Brugia malayi ORL1-like opioid receptor 0.0036 0.0378 0.0404
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0369 0.0367
Schistosoma mansoni glucose transport protein 0.0116 0.1934 0.1933
Schistosoma mansoni aryl hydrocarbon receptor nuclear translocator homolog (darnt) 0.0018 0.004 0.0038
Onchocerca volvulus Heat shock factor protein 2 homolog 0.0097 0.1554 0.2558
Trichomonas vaginalis glucosylceramidase, putative 0.033 0.6046 0.6446
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0064 0.0062
Onchocerca volvulus Glucosylceramidase homolog 0.033 0.6046 1
Echinococcus multilocularis G protein coupled receptor 139 0.0036 0.0378 0.0376
Entamoeba histolytica protein kinase, putative 0.0036 0.0381 0.054
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0116 0.1934 0.1933
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0373 0.0388
Entamoeba histolytica hypothetical protein 0.0023 0.0133 0.0076
Echinococcus multilocularis g protein coupled receptor 0.0036 0.0378 0.0376
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.0387 1
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0041 0.0478 0.079
Echinococcus granulosus orexin receptor type 2 0.0036 0.0378 0.0376
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0026 0.0195 0.0745
Loa Loa (eye worm) hypothetical protein 0.0097 0.1554 0.1656
Schistosoma mansoni loxhd1 0.0019 0.0064 0.0062
Echinococcus multilocularis sex peptide receptor 0.0036 0.0378 0.0376
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0387 0.0639
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0035 0.0367 0.0381
Brugia malayi jmjC domain containing protein 0.006 0.0847 0.0904
Entamoeba histolytica hypothetical protein 0.0035 0.0369 0.0519
Brugia malayi hypothetical protein 0.0019 0.0064 0.0068
Loa Loa (eye worm) hypothetical protein 0.0036 0.0378 0.0401
Echinococcus granulosus transient receptor potential ion channel A 0.02 0.3544 0.3543
Trichomonas vaginalis glucosylceramidase, putative 0.0348 0.6388 0.6811
Echinococcus granulosus G protein coupled receptor 139 0.0036 0.0378 0.0376
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0036 0.0378 0.0376
Brugia malayi Serotonin receptor 0.0036 0.0378 0.0404
Trichomonas vaginalis sucrase-isomaltase, putative 0.0035 0.0373 0.0388
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0036 0.0378 0.0376
Echinococcus granulosus transient receptor potential gamma protein 0.021 0.3722 0.3721
Echinococcus multilocularis neutral alpha glucosidase AB 0.0035 0.0373 0.0371
Schistosoma mansoni hypothetical protein 0.0116 0.1934 0.1933
Schistosoma mansoni neuropeptide receptor 0.0036 0.0378 0.0376
Trichomonas vaginalis glucosylceramidase, putative 0.0348 0.6388 0.6811
Brugia malayi Latrophilin receptor protein 2 0.0068 0.0999 0.1066
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0036 0.0378 0.0401
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0298 0.5423 0.578
Echinococcus multilocularis calcium dependent protein kinase 0.0033 0.0338 0.0336
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0036 0.0378 0.0404
Echinococcus multilocularis G-protein coupled receptor, putative 0.0036 0.0378 0.0376
Brugia malayi MH2 domain containing protein 0.0018 0.0034 0.0036
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0036 0.0378 0.0376
Brugia malayi putative neuropeptide receptor 0.0036 0.0378 0.0404
Schistosoma mansoni serine/threonine protein kinase 0.0036 0.0381 0.0378
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0036 0.0378 0.0401
Echinococcus multilocularis g protein coupled receptor 0.0036 0.0378 0.0376
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0093 0.1903
Trichomonas vaginalis maltase-glucoamylase, putative 0.0035 0.0373 0.0388
Echinococcus multilocularis synaptic vesicle 2 protein 0.0016 0.001 0.0008
Brugia malayi Sugar transporter family protein 0.0016 0.001 0.001
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0387 0.0385
Plasmodium falciparum protein kinase 6 0.0494 0.92 1
Brugia malayi putative neuropeptide receptor NPR1 0.0036 0.0378 0.0404
Trypanosoma cruzi hexose transporter, putative 0.0036 0.0389 0.8137
Echinococcus granulosus g-protein coupled receptor 0.0036 0.0378 0.0376
Loa Loa (eye worm) hypothetical protein 0.0036 0.0378 0.0401
Schistosoma mansoni amine GPCR 0.0036 0.0378 0.0376
Loa Loa (eye worm) hypothetical protein 0.0036 0.0378 0.0401
Trichomonas vaginalis glucosylceramidase, putative 0.0504 0.9374 1
Trichomonas vaginalis glucosylceramidase, putative 0.033 0.6046 0.6446
Echinococcus multilocularis transient receptor potential ion channel A 0.02 0.3544 0.3543
Echinococcus multilocularis orexin receptor type 2 0.0036 0.0378 0.0376
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0298 0.5423 0.578
Trypanosoma brucei glucose transporter 2A 0.0036 0.0389 0.8137
Echinococcus multilocularis neuropeptide receptor A26 0.0036 0.0378 0.0376
Loa Loa (eye worm) hypothetical protein 0.0036 0.0378 0.0401
Echinococcus granulosus tm gpcr rhodopsin 0.0036 0.0378 0.0376
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0036 0.0378 0.0376
Plasmodium vivax multidomain scavenger receptor, putative 0.0019 0.0064 0.0067
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0035 0.0367 0.0365
Schistosoma mansoni biogenic amine receptor 0.0036 0.0378 0.0376
Trypanosoma brucei glucose transporter, putative 0.0036 0.0389 0.8137
Schistosoma mansoni neuropeptide F-like receptor 0.0036 0.0378 0.0376
Schistosoma mansoni lysyl-tRNA synthetase 0.0026 0.0195 0.0193
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0026 0.0195 0.0476
Echinococcus multilocularis serotonin receptor 0.0278 0.5041 0.504
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0036 0.0381 0.0629
Loa Loa (eye worm) TYRA-2 protein 0.0036 0.0378 0.0401
Loa Loa (eye worm) hypothetical protein 0.0018 0.004 0.004
Echinococcus granulosus calcium dependent protein kinase 0.0033 0.0338 0.0336
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0035 0.0367 0.0391
Brugia malayi Major Facilitator Superfamily protein 0.0016 0.001 0.001
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0035 0.0367 0.0365
Brugia malayi G protein-coupled receptor F59B2.13 0.0036 0.0378 0.0404
Brugia malayi MH2 domain containing protein 0.0018 0.0034 0.0036
Echinococcus granulosus neuropeptide Y receptor 0.0036 0.0378 0.0376
Schistosoma mansoni transient receptor potential channel 0.0139 0.2374 0.2372
Schistosoma mansoni myosin xvIII 0.0036 0.0378 0.0376
Schistosoma mansoni neuropeptide F-like receptor 0.0036 0.0378 0.0376
Loa Loa (eye worm) melatonin receptor type 1A 0.0036 0.0378 0.0401
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.006 0.0847 0.0845
Brugia malayi jmjC domain containing protein 0.006 0.0847 0.0904
Echinococcus granulosus somatostatin receptor 0.0036 0.0378 0.0376
Toxoplasma gondii sugar transporter ST1 0.0016 0.001 0.0013
Onchocerca volvulus 0.0036 0.0378 0.0611
Loa Loa (eye worm) sugar transporter 0.0116 0.1934 0.2062
Loa Loa (eye worm) major facilitator superfamily transporter 0.0016 0.001 0.0008
Plasmodium falciparum importin beta, putative 0.0028 0.0236 0.0254
Schistosoma mansoni opsin-like receptor 0.0036 0.0378 0.0376
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0168 0.018
Brugia malayi Sugar transporter family protein 0.0116 0.1934 0.2063
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0036 0.0381 0.0629
Brugia malayi aryl hydrocarbon receptor nuclear translocator protein, putative 0.0018 0.004 0.0043
Echinococcus granulosus tachykinin peptides receptor 99D 0.0036 0.0378 0.0376
Plasmodium falciparum hexose transporter 0.0116 0.1934 0.2101
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0068 0.0999 0.0997
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0116 0.1934 0.1933
Brugia malayi hypothetical protein 0.0016 0.001 0.001
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0068 0.0999 0.0997
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0036 0.0378 0.0376
Entamoeba histolytica heat shock transcription factor, putative 0.0097 0.1554 0.2742
Echinococcus granulosus GPCR family 2 0.0068 0.0999 0.0997
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0036 0.0378 0.0404
Loa Loa (eye worm) hypothetical protein 0.0036 0.0378 0.0401
Schistosoma mansoni neuropeptide receptor 0.0036 0.0378 0.0376
Plasmodium vivax importin-beta 2, putative 0.0028 0.0236 0.0254
Entamoeba histolytica protein kinase, putative 0.0036 0.0381 0.054
Echinococcus granulosus nuclear factor of activated T cells 5 0.0072 0.1074 0.1072
Trichomonas vaginalis CAMK family protein kinase 0.0036 0.0381 0.0396
Echinococcus granulosus 7tm_1 domain containing protein 0.0036 0.0378 0.0376
Plasmodium vivax calcium-dependent protein kinase, putative 0.0036 0.0381 0.0412
Brugia malayi GnHR receptor homolog 0.0036 0.0378 0.0404
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0036 0.0378 0.0376
Onchocerca volvulus 0.0036 0.0378 0.0611
Loa Loa (eye worm) hypothetical protein 0.0036 0.0378 0.0401
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0373 0.7786
Brugia malayi major facilitator superfamily protein 0.0016 0.001 0.001
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0168 0.3473
Leishmania major lysyl-tRNA synthetase, putative 0.0026 0.0195 0.3646
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.002 0.008 0.0075
Loa Loa (eye worm) hypothetical protein 0.0036 0.0378 0.0401
Echinococcus multilocularis solute carrier family 22 0.0016 0.001 0.0008
Echinococcus multilocularis survival motor neuron protein 1 0.0254 0.4575 0.4573
Schistosoma mansoni lipoxygenase 0.0115 0.1904 0.1902
Onchocerca volvulus 0.0036 0.0378 0.0611
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0298 0.5423 0.578
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0373 0.0388
Loa Loa (eye worm) hypothetical protein 0.0016 0.001 0.0008
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0036 0.0378 0.0376
Schistosoma mansoni hypothetical protein 0.0068 0.0999 0.0997
Echinococcus granulosus lysine specific demethylase 5A 0.006 0.0847 0.0845
Loa Loa (eye worm) hypothetical protein 0.0036 0.0378 0.0401
Schistosoma mansoni transient receptor potential channel 4 0.021 0.3722 0.3721
Loa Loa (eye worm) hypothetical protein 0.0036 0.0378 0.0401
Toxoplasma gondii transporter, major facilitator family protein 0.0016 0.001 0.0013
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0036 0.0381 0.0378
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0387 0.0385
Brugia malayi MH1 domain containing protein 0.0018 0.0034 0.0036
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0026 0.0195 0.0198
Schistosoma mansoni amine GPCR 0.0036 0.0378 0.0376
Schistosoma mansoni adenoreceptor 0.0036 0.0378 0.0376
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0373 0.0388
Leishmania major glucose transporter/membrane transporter D2, putative 0.0036 0.0389 0.7332
Entamoeba histolytica heat shock transcription factor, putative 0.0097 0.1554 0.2742
Echinococcus multilocularis g protein coupled receptor 0.0036 0.0378 0.0376
Echinococcus granulosus neuropeptide receptor A26 0.0036 0.0378 0.0376
Trypanosoma brucei glucose transporter, putative 0.0036 0.0389 0.8137
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0032 0.0314 0.0971
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0036 0.0381 0.0378
Onchocerca volvulus 0.0036 0.0378 0.0611
Leishmania major GTP-binding protein, putative 0.0021 0.0093 0.1715
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0387 0.1518

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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