Detailed information for compound 573680

Basic information

Technical information
  • TDR Targets ID: 573680
  • Name: ethyl (E)-3-acetoxyprop-2-enoate
  • MW: 158.152 | Formula: C7H10O4
  • H donors: 0 H acceptors: 2 LogP: 0.48 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOC(=O)C=COC(=O)C
  • InChi: 1S/C7H10O4/c1-3-10-7(9)4-5-11-6(2)8/h4-5H,3H2,1-2H3/b5-4+
  • InChiKey: CTQAODRCOVPAEH-SNAWJCMRSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (E)-3-acetoxy-2-propenoic acid ethyl ester
  • ethyl (E)-3-acetyloxyprop-2-enoate
  • acetic acid [(E)-3-ethoxy-3-keto-prop-1-enyl] ester
  • ethyl acetoxyacrylate
  • (E)-3-acetoxyprop-2-enoic acid ethyl ester
  • 61381-00-8
  • EINECS 262-751-2
  • Ethyl 3-acetoxyacrylate

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0161 0.109 0.108
Schistosoma mansoni cpg binding protein 0.0063 0.0348 0.0338
Wolbachia endosymbiont of Brugia malayi O-methyltransferase 0.0061 0.0332 1
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0013 0.0024
Echinococcus multilocularis Protein lozenge 0.0054 0.0282 0.0272
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0318 1
Echinococcus granulosus zinc finger protein 0.0041 0.0186 0.0176
Brugia malayi O-methyltransferase family protein 0.0061 0.0332 0.1032
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0059 0.032 0.0807
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0103 0.0093
Echinococcus granulosus PHD finger protein rhinoceros 0.0028 0.0089 0.0078
Brugia malayi hypothetical protein 0.0431 0.3124 1
Mycobacterium ulcerans DNA polymerase IV 0.0059 0.0318 0.0715
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0041 0.0187 0.0176
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0059 0.0318 0.0764
Onchocerca volvulus 0.0431 0.3124 1
Loa Loa (eye worm) PHD-finger family protein 0.004 0.0177 0.0536
Loa Loa (eye worm) apoptosis regulator protein 0.0161 0.109 0.3466
Trypanosoma brucei unspecified product 0.0052 0.0269 0.8412
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0054 0.0124
Onchocerca volvulus 0.0061 0.0332 0.0801
Loa Loa (eye worm) hypothetical protein 0.0431 0.3124 1
Leishmania major DNA polymerase kappa, putative 0.0039 0.0171 0.5145
Schistosoma mansoni zinc finger protein 0.0041 0.0186 0.0176
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0089 0.1238
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0106 0.0671 0.0662
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0353 0.0343
Schistosoma mansoni hypothetical protein 0.0165 0.1118 0.1109
Echinococcus multilocularis chromobox protein 1 0.0068 0.0386 0.0376
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0204 0.1411 0.4497
Loa Loa (eye worm) hypothetical protein 0.0431 0.3124 1
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0013 0.0024
Echinococcus granulosus chromobox protein 1 0.0068 0.0386 0.0376
Plasmodium vivax SET domain protein, putative 0.003 0.0103 1
Echinococcus granulosus histone acetyltransferase MYST2 0.0106 0.0671 0.0662
Schistosoma mansoni ap endonuclease 0.0018 0.0013 0.0002
Loa Loa (eye worm) jmjC domain-containing protein 0.0041 0.0186 0.0563
Schistosoma mansoni jumonji/arid domain-containing protein 0.0041 0.0186 0.0175
Trypanosoma brucei DNA polymerase kappa, putative 0.0036 0.0147 0.4395
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0039 0.0171 0.0415
Echinococcus multilocularis cpg binding protein 0.0063 0.0348 0.0338
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.001 0.0017
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0059 0.032 0.031
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0353 0.0343
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0093 0.0575 0.0565
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0103 0.1438
Echinococcus multilocularis peregrin 0.0033 0.0123 0.0113
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0086 0.0075
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0183 0.0437
Schistosoma mansoni cpg binding protein 0.0056 0.0296 0.0286
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0119 0.0775 0.0765
Schistosoma mansoni o-methyltransferase 0.0061 0.0332 0.0322
Trypanosoma brucei DNA polymerase kappa, putative 0.0036 0.0147 0.4395
Brugia malayi N-terminal motif family protein 0.0176 0.1199 0.3818
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0047 0.0229 0.0219
Echinococcus granulosus histone lysine methyltransferase setb 0.0063 0.0353 0.0343
Schistosoma mansoni myelin transcription factor 1 myt1 0.0106 0.0671 0.0662
Schistosoma mansoni sex comb on midleg homolog 0.0093 0.0575 0.0565
Brugia malayi Pre-SET motif family protein 0.003 0.0103 0.0297
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0047 0.0229 0.0219
Brugia malayi ImpB/MucB/SamB family protein 0.0033 0.0122 0.036
Loa Loa (eye worm) hypothetical protein 0.0033 0.0122 0.036
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0089 0.0546 0.0536
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0318 1
Entamoeba histolytica hypothetical protein 0.0035 0.0139 0.0306
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0161 0.0385
Schistosoma mansoni bromodomain containing protein 0.0126 0.0827 0.0818
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0078 0.0182
Schistosoma mansoni chromobox protein 0.0068 0.0386 0.0376
Echinococcus granulosus peregrin 0.0033 0.0123 0.0113
Brugia malayi Heterochromatin protein 1 0.0068 0.0386 0.1206
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0318 1
Loa Loa (eye worm) CXXC zinc finger family protein 0.0056 0.0296 0.0917
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0171 0.5189
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0093 0.0575 0.0565
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0318 1
Schistosoma mansoni microtubule-associated protein tau 0.1343 1 1
Echinococcus granulosus dna polymerase kappa 0.0059 0.0318 0.0307
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0094 0.2667
Loa Loa (eye worm) glutaminase 2 0.0266 0.188 0.6005
Loa Loa (eye worm) PHD-finger family protein 0.0028 0.0089 0.0251
Echinococcus multilocularis dna polymerase eta 0.0033 0.0122 0.0112
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0054 0.0124
Schistosoma mansoni DNA polymerase eta 0.0033 0.0122 0.0112
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0093 0.0575 0.0565
Loa Loa (eye worm) hypothetical protein 0.0138 0.0912 0.2897
Trichomonas vaginalis set domain proteins, putative 0.0232 0.1622 0.3925
Onchocerca volvulus 0.0093 0.0575 0.1601
Brugia malayi hypothetical protein 0.0035 0.0139 0.0412
Brugia malayi O-methyltransferase 0.0061 0.0332 0.1032
Loa Loa (eye worm) jmjC domain-containing protein 0.0059 0.0316 0.0982
Brugia malayi jmjC domain containing protein 0.0041 0.0186 0.0563
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0013 0.0007
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0018 0.0013 0.0003
Trypanosoma cruzi DNA polymerase kappa, putative 0.0059 0.0318 1
Loa Loa (eye worm) hypothetical protein 0.0061 0.0332 0.1032
Trypanosoma brucei unspecified product 0.0023 0.0046 0.1079
Trypanosoma cruzi DNA polymerase kappa, putative 0.0059 0.0318 1
Mycobacterium ulcerans methyltransferase 0.0061 0.0332 0.0748
Trypanosoma brucei DNA polymerase eta, putative 0.0033 0.0122 0.3601
Echinococcus granulosus polycomb protein SCMH1 0.0093 0.0575 0.0565
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0089 0.0546 0.0536
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0033 0.0122 0.0112
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.032 0.0721
Schistosoma mansoni methyl-cpg binding protein mbd 0.0033 0.0125 0.0115
Loa Loa (eye worm) hypothetical protein 0.0038 0.0161 0.0484
Schistosoma mansoni apoptosis regulator bax 0.0161 0.109 0.108
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0013 0.0007
Echinococcus multilocularis jumonji domain containing protein 0.0039 0.0172 0.0162
Echinococcus granulosus SAM and MBT domain containing protein 0.0093 0.0575 0.0565
Echinococcus granulosus dna polymerase eta 0.0033 0.0122 0.0112
Mycobacterium tuberculosis Probable methyltransferase 0.0061 0.0332 0.0838
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0089 0.0546 0.172
Brugia malayi O-methyltransferase family protein 0.0061 0.0332 0.1032
Loa Loa (eye worm) hypothetical protein 0.0086 0.0524 0.1651
Loa Loa (eye worm) hypothetical protein 0.0049 0.0241 0.0742
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0106 0.0671 0.2123
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0094 0.2667
Loa Loa (eye worm) hypothetical protein 0.0075 0.0438 0.1372
Brugia malayi mbt repeat family protein 0.0093 0.0575 0.1812
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0386 0.0929
Schistosoma mansoni hypothetical protein 0.004 0.0177 0.0167
Loa Loa (eye worm) O-methyltransferase 0.0061 0.0332 0.1032
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0013 0.0002
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0054 0.0124
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0054 0.0124
Trypanosoma cruzi DNA polymerase eta, putative 0.0033 0.0122 0.3601
Brugia malayi PHD-finger family protein 0.0052 0.0264 0.0815
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0139 0.0128
Schistosoma mansoni ap endonuclease 0.0018 0.0013 0.0002
Schistosoma mansoni o-methyltransferase 0.0061 0.0332 0.0322
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0318 1
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0038 0.0161 0.0239
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0139 0.0128
Echinococcus granulosus lysine specific demethylase 5A 0.0041 0.0186 0.0175
Brugia malayi Pre-SET motif family protein 0.0204 0.1411 0.4497
Echinococcus granulosus jumonji domain containing protein 0.0039 0.0172 0.0162
Brugia malayi CXXC zinc finger family protein 0.0056 0.0296 0.0917
Onchocerca volvulus 0.0056 0.0296 0.0684
Echinococcus multilocularis lysine specific demethylase 5A 0.0034 0.0134 0.0123
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0119 0.0775 0.0765
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0024 0.0057 0.0047
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0386 0.0929
Mycobacterium tuberculosis Probable catechol-O-methyltransferase 0.0523 0.3822 1
Schistosoma mansoni methyl-cpg binding protein mbd 0.0033 0.0125 0.0115
Brugia malayi polk-prov protein 0.0036 0.0147 0.0438
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0318 1
Loa Loa (eye worm) glutaminase 0.0266 0.188 0.6005
Trichomonas vaginalis glutaminase, putative 0.0266 0.188 0.4552
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0054 0.0124
Mycobacterium ulcerans DNA polymerase IV 0.0059 0.0318 0.0715
Schistosoma mansoni mixed-lineage leukemia protein mll 0.012 0.0777 0.0767
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0059 0.032 1
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.032 0.031
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0089 0.0546 0.0536
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0176 0.1199 0.3658
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0089 0.0546 0.0536
Loa Loa (eye worm) MBCTL1 0.0106 0.0671 0.2123
Schistosoma mansoni hypothetical protein 0.0035 0.0139 0.0128
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0161 0.0385
Schistosoma mansoni o-methyltransferase 0.0061 0.0332 0.0322
Loa Loa (eye worm) hypothetical protein 0.0063 0.0353 0.1101
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0033 0.0122 0.0112
Echinococcus granulosus chromobox protein 1 0.0068 0.0386 0.0376
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0089 0.0546 0.172
Schistosoma mansoni chromobox protein 0.0068 0.0386 0.0376
Trypanosoma cruzi ISWI complex protein 0.003 0.0099 0.2837
Brugia malayi Bromodomain containing protein 0.0075 0.0437 0.1369
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0089 0.0546 0.0536
Entamoeba histolytica hypothetical protein 0.0035 0.0139 0.0306
Schistosoma mansoni o-methyltransferase 0.0061 0.0332 0.0322
Brugia malayi jmjC domain containing protein 0.0093 0.0575 0.1814
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0318 1
Entamoeba histolytica hypothetical protein 0.0035 0.0139 0.0306
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0318 1
Schistosoma mansoni jumonji/arid domain-containing protein 0.0041 0.0186 0.0175
Plasmodium vivax hypothetical protein, conserved 0.0028 0.0089 0.8413
Brugia malayi F/Y-rich N-terminus family protein 0.0031 0.0109 0.0318
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.032 0.031
Loa Loa (eye worm) mbt repeat family protein 0.0093 0.0575 0.1812
Echinococcus multilocularis dna polymerase kappa 0.0059 0.0318 0.0307
Onchocerca volvulus 0.0041 0.0187 0.0323
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0094 0.2667
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.007 0.0402 0.0392
Schistosoma mansoni hypothetical protein 0.0161 0.109 0.108
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0369 0.2661 0.2653
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0059 0.032 0.031
Trypanosoma brucei unspecified product 0.0023 0.0046 0.1079
Giardia lamblia DINP protein human, muc B family 0.0039 0.0171 1
Toxoplasma gondii aldehyde dehydrogenase 0.0059 0.032 0.4473
Echinococcus granulosus cpg binding protein 0.0063 0.0348 0.0338
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.032 0.0721
Echinococcus multilocularis PHD finger protein rhinoceros 0.0028 0.0089 0.0078
Trypanosoma brucei ISWI complex protein 0.003 0.0099 0.2837
Echinococcus granulosus geminin 0.0165 0.1118 0.1109
Entamoeba histolytica deoxycytidyl transferase, putative 0.0033 0.0122 0.0267
Loa Loa (eye worm) hypothetical protein 0.0106 0.0671 0.2123
Brugia malayi mbt repeat family protein 0.0093 0.0575 0.1812
Schistosoma mansoni hypothetical protein 0.0568 0.4157 0.4151
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0139 0.0128
Loa Loa (eye worm) hypothetical protein 0.0036 0.0147 0.0438
Brugia malayi glutaminase DH11.1 0.0266 0.188 0.6005
Brugia malayi ImpB/MucB/SamB family protein 0.0033 0.0122 0.036
Echinococcus multilocularis zinc finger protein 0.0041 0.0186 0.0176
Toxoplasma gondii histone lysine methyltransferase SET1 0.0112 0.0716 1
Leishmania major DNA polymerase eta, putative 0.0033 0.0122 0.3571
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0318 1
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.007 0.0402 0.0392
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0089 0.0546 0.0536
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0063 0.0353 0.0343
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0161 0.109 0.108
Brugia malayi PHD-finger family protein 0.0028 0.0089 0.0251
Treponema pallidum exodeoxyribonuclease (exoA) 0.0018 0.0013 0.5
Echinococcus multilocularis histone acetyltransferase MYST2 0.0106 0.0671 0.0662
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0054 0.0124
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0161 0.109 0.108
Loa Loa (eye worm) bromodomain containing protein 0.0034 0.0134 0.0397
Trypanosoma brucei DNA polymerase IV, putative 0.0059 0.0318 1
Schistosoma mansoni glutaminase 0.0266 0.188 0.1872
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0093 0.0575 0.1601
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0161 0.109 0.3466
Echinococcus multilocularis polycomb protein SCMH1 0.0093 0.0575 0.0565
Brugia malayi Bromodomain containing protein 0.0033 0.0123 0.0363
Mycobacterium ulcerans glutaminase 0.0266 0.188 0.4377
Trypanosoma brucei DNA polymerase IV, putative 0.0059 0.0318 1
Brugia malayi Bromodomain containing protein 0.0149 0.0999 0.3175
Trypanosoma brucei DNA polymerase IV, putative 0.0052 0.0269 0.8412
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0078 0.0182
Mycobacterium leprae PROBABLE METHYLTRANSFERASE 0.0061 0.0332 0.5
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0106 0.0671 0.0662
Loa Loa (eye worm) hypothetical protein 0.0093 0.0575 0.1812
Echinococcus multilocularis SAM and MBT domain containing protein 0.0093 0.0575 0.0565
Mycobacterium ulcerans O-methyltransferase 0.0584 0.4279 1
Schistosoma mansoni terminal deoxycytidyl transferase 0.0033 0.0122 0.0112
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0013 0.0002
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.032 0.0721
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0103 0.0093
Loa Loa (eye worm) histone methyltransferase 0.0018 0.0013 0.0009
Schistosoma mansoni cpg binding protein 0.0063 0.0348 0.0338
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0028 0.0089 0.0078
Loa Loa (eye worm) hypothetical protein 0.0161 0.109 0.3466
Echinococcus granulosus methyl CpG binding domain protein 2 0.0033 0.0125 0.0115
Schistosoma mansoni zinc finger protein 0.003 0.0099 0.0089
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0183 0.0311
Echinococcus multilocularis chromobox protein 1 0.0068 0.0386 0.0376
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0033 0.0122 0.0112
Schistosoma mansoni hypothetical protein 0.0165 0.1118 0.1109
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0183 0.0437
Echinococcus multilocularis geminin 0.0165 0.1118 0.1109
Trypanosoma cruzi DNA polymerase kappa, putative 0.0059 0.0318 1
Schistosoma mansoni hypothetical protein 0.0161 0.109 0.108
Onchocerca volvulus 0.0232 0.1622 0.505
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0161 0.109 0.108
Schistosoma mansoni hypothetical protein 0.0796 0.5876 0.5872
Loa Loa (eye worm) hypothetical protein 0.0079 0.0472 0.1484
Schistosoma mansoni hypothetical protein 0.0161 0.109 0.108
Echinococcus multilocularis dnaJ subfamily B 0.0796 0.5876 0.5872
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0161 0.109 0.108
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0033 0.0122 0.036
Entamoeba histolytica dual specificity protein phosphatase, putative 0.0564 0.4128 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0099 0.0286
Loa Loa (eye worm) heterochromatin protein 1 0.0068 0.0386 0.1206
Leishmania major hypothetical protein, conserved 0.003 0.0099 0.2813
Trichomonas vaginalis DNA polymerase eta, putative 0.0059 0.0318 0.0764
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0018 0.0013 0.0003
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0369 0.2661 0.2653
Loa Loa (eye worm) runx1 0.0054 0.0282 0.0873
Echinococcus granulosus dnaJ subfamily B 0.0796 0.5876 0.5872
Schistosoma mansoni hypothetical protein 0.0028 0.0089 0.0078
Schistosoma mansoni sex comb on midleg homolog 0.0093 0.0575 0.0565
Echinococcus multilocularis microtubule associated protein 2 0.1343 1 1
Trichomonas vaginalis pps1 dual specificty phosphatase, putative 0.0564 0.4128 1
Schistosoma mansoni hypothetical protein 0.003 0.0099 0.0089
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0054 0.0124
Entamoeba histolytica hypothetical protein 0.0035 0.0139 0.0306
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0054 0.0124
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.001 0.0017
Loa Loa (eye worm) hypothetical protein 0.0028 0.0089 0.0251
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0033 0.0125 0.0115
Toxoplasma gondii exonuclease III APE 0.0018 0.0013 0.0177
Brugia malayi O-methyltransferase family protein 0.0061 0.0332 0.1032
Onchocerca volvulus 0.0061 0.0332 0.0801
Echinococcus granulosus fetal alzheimer antigen falz 0.0047 0.0229 0.0219
Mycobacterium tuberculosis Conserved hypothetical protein 0.0033 0.0122 0.0288
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0039 0.0171 0.5145
Giardia lamblia PHD finger protein 15 0.0028 0.0089 0.4799
Brugia malayi chromobox protein homolog 3 0.0038 0.0161 0.0484
Onchocerca volvulus 0.003 0.0099 0.0035
Loa Loa (eye worm) hypothetical protein 0.0176 0.1199 0.3818
Plasmodium falciparum phd finger protein, putative 0.0028 0.0089 1
Trypanosoma cruzi ISWI complex protein 0.003 0.0099 0.2837
Schistosoma mansoni lozenge 0.0054 0.0282 0.0272
Trypanosoma cruzi DNA polymerase kappa, putative 0.0059 0.0318 1
Schistosoma mansoni jumonji domain containing protein 0.0074 0.0431 0.0421
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0089 0.0546 0.0536
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0089 0.1238

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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