Detailed information for compound 619129

Basic information

Technical information
  • TDR Targets ID: 619129
  • Name: N-[2-(4-methoxyphenyl)-4,6-dihydrothieno[3,4- d]pyrazol-3-yl]-2-methylbenzamide
  • MW: 365.449 | Formula: C20H19N3O2S
  • H donors: 1 H acceptors: 2 LogP: 3.45 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc(cc1)n1nc2c(c1NC(=O)c1ccccc1C)CSC2
  • InChi: 1S/C20H19N3O2S/c1-13-5-3-4-6-16(13)20(24)21-19-17-11-26-12-18(17)22-23(19)14-7-9-15(25-2)10-8-14/h3-10H,11-12H2,1-2H3,(H,21,24)
  • InChiKey: NMQSXRRMHFJCLM-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-[2-(4-methoxyphenyl)-4,6-dihydrothieno[3,4-d]pyrazol-3-yl]-2-methyl-benzamide
  • Oprea1_840697
  • ZINC04077170

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis mismatch repair protein Mlh1C (mutL homolog) 0.0012 0.0005 0.0038
Giardia lamblia Heat shock protein HSP 90-alpha 0.0047 0.0042 0.0577
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0012 0.0005 0.0038
Loa Loa (eye worm) hypothetical protein 0.0052 0.0047 0.0649
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0009 0.0002 0.0002
Trypanosoma cruzi hypothetical protein, conserved 0.3322 0.3492 1
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0052 0.0047 0.0047
Brugia malayi DKFZp564C0469 protein 0.001 0.0002 0.0006
Loa Loa (eye worm) hypothetical protein 0.0052 0.0047 0.0649
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0062 0.0904
Brugia malayi hypothetical protein 0.0052 0.0047 0.065
Trichomonas vaginalis PIKK family atypical protein kinase 0.0662 0.0689 1
Trichomonas vaginalis esterase, putative 0.0038 0.0032 0.0434
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0012 0.0005 0.0042
Echinococcus multilocularis GPCR, family 2 0.0048 0.0042 0.0042
Echinococcus multilocularis regulator of G protein signaling 7 0.0009 0.0002 0.0002
Plasmodium falciparum heat shock protein 90 0.0059 0.0055 0.4226
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0662 0.0689 0.189
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0127 0.0126 0.0126
Schistosoma mansoni endoplasmin 0.0059 0.0055 0.0792
Brugia malayi G protein-coupled receptor F59B2.13 0.0052 0.0047 0.065
Trichomonas vaginalis PIKK family atypical protein kinase 0.0662 0.0689 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0052 0.0047 0.0675
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.0002 0.0002
Mycobacterium ulcerans two component sensory transduction histidine kinase MtrB 0.0012 0.0005 0.0661
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0052 0.0047 0.0675
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0127 0.0126 0.0355
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0012 0.0005 0.0661
Schistosoma mansoni fkbp-rapamycin associated protein 0.0373 0.0385 0.559
Brugia malayi Endoplasmin precursor 0.0059 0.0055 0.0768
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0662 0.0689 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0373 0.0385 0.5576
Echinococcus granulosus rhodopsin orphan GPCR 0.0052 0.0047 0.0047
Trichomonas vaginalis PIKK family atypical protein kinase 0.0127 0.0126 0.1805
Mycobacterium ulcerans two component sensor histidine kinase PrrB 0.0012 0.0005 0.0661
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0127 0.0126 0.1831
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0127 0.0126 0.0126
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0127 0.0126 1
Onchocerca volvulus 0.0052 0.0047 0.2342
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0662 0.0689 0.0689
Brugia malayi Pax transcription activation domain interacting protein 0.001 0.0002 0.0006
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0038 0.0032 0.1122
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0062 0.0904
Echinococcus multilocularis rhodopsin orphan GPCR 0.0052 0.0047 0.0047
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0047 0.0042 0.3199
Leishmania major heat shock protein 83-1 0.0059 0.0055 0.0137
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0127 0.0126 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0047 0.0675
Trichomonas vaginalis PIKK family atypical protein kinase 0.0662 0.0689 1
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0032 0.0434
Onchocerca volvulus 0.0052 0.0047 0.2342
Schistosoma mansoni dishevelled 0.0009 0.0002 0.0028
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0127 0.0126 0.0355
Echinococcus granulosus neuropeptide receptor 0.0052 0.0047 0.0047
Leishmania major heat shock protein 83-1 0.0059 0.0055 0.0137
Schistosoma mansoni cpg binding protein 0.0032 0.0026 0.0374
Mycobacterium tuberculosis Conserved hypothetical protein 0.0127 0.0126 0.5009
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0052 0.0047 0.0047
Trypanosoma brucei heat shock protein 90, putative 0.0059 0.0055 0.0763
Plasmodium falciparum heat shock protein 90, putative 0.0024 0.0018 0.125
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0127 0.0126 0.181
Plasmodium vivax hypothetical protein, conserved 0.0127 0.0126 1
Schistosoma mansoni dishevelled 0.0009 0.0002 0.0028
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0373 0.0385 0.0385
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0373 0.0385 0.5576
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0662 0.0689 1
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0127 0.0126 0.1805
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0127 0.0126 0.1808
Schistosoma mansoni growth hormone secretagogue receptor 0.0052 0.0047 0.0675
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0662 0.0689 1
Mycobacterium ulcerans heat shock protein 90 0.0047 0.0042 1
Brugia malayi Transient-receptor-potential like protein 0.0038 0.0032 0.0441
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0052 0.0047 0.0047
Trichomonas vaginalis PIKK family atypical protein kinase 0.0662 0.0689 1
Echinococcus granulosus g protein coupled receptor 0.0052 0.0047 0.0047
Brugia malayi hypothetical protein 0.0052 0.0047 0.065
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0052 0.0047 0.065
Schistosoma mansoni hypothetical protein 0.0431 0.0446 0.6466
Plasmodium falciparum DNA gyrase subunit B 0.0012 0.0005 0.0211
Echinococcus multilocularis rhodopsin orphan GPCR 0.0052 0.0047 0.0047
Giardia lamblia GTOR 0.0662 0.0689 1
Loa Loa (eye worm) latrophilin receptor protein 2 0.0048 0.0042 0.0588
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0047 0.0675
Plasmodium falciparum phosphatidylinositol 4-kinase 0.0127 0.0126 1
Loa Loa (eye worm) phosphatidylinositol kinase 0.0127 0.0126 0.1808
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0052 0.0047 0.0675
Schistosoma mansoni cpg binding protein 0.0032 0.0026 0.0374
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0052 0.0047 0.0047
Toxoplasma gondii ABC1 family protein 0.0038 0.0032 0.0438
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.0127 0.0126 0.0126
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0009 0.0002 0.0002
Plasmodium vivax heat shock protein, putative 0.0024 0.0018 0.125
Trypanosoma brucei Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0012 0.0005 0.0038
Loa Loa (eye worm) hypothetical protein 0.0052 0.0047 0.0649
Entamoeba histolytica heat shock protein 90, putative 0.0059 0.0055 0.0763
Schistosoma mansoni transient receptor potential channel 0.0102 0.01 0.1447
Toxoplasma gondii Hsp90 domain-containing protein 0.0024 0.0018 0.0229
Echinococcus multilocularis segment polarity protein dishevelled 0.0009 0.0002 0.0002
Echinococcus multilocularis serotonin receptor 0.0052 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0052 0.0047 0.0649
Mycobacterium leprae PUTATIVE TWO COMPONENT SENSOR HISTIDINE KINASE SENX3 0.0012 0.0005 0.0211
Echinococcus multilocularis cpg binding protein 0.0032 0.0026 0.0026
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0024 0.0018 0.0226
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0416 0.043 0.6229
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0012 0.0005 0.0044
Brugia malayi hypothetical protein 0.0052 0.0047 0.065
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0048 0.0042 0.0042
Brugia malayi RNA binding protein 0.0067 0.0062 0.088
Mycobacterium leprae conserved hypothetical protein 0.0127 0.0126 1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0052 0.0047 0.0675
Echinococcus granulosus heat shock protein 0.0059 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0052 0.0047 0.0649
Leishmania major phosphatidylinositol kinase, putative 0.0127 0.0126 0.0335
Echinococcus multilocularis rhodopsin orphan GPCR 0.0052 0.0047 0.0047
Schistosoma mansoni adenoreceptor 0.0052 0.0047 0.0675
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0127 0.0126 0.1805
Brugia malayi Dopamine receptor 0.0052 0.0047 0.065
Loa Loa (eye worm) phosphatidylinositol 3 0.0127 0.0126 0.1808
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0662 0.0689 0.1969
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0127 0.0126 0.1808
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0047 0.0675
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0047 0.0042 1
Trichomonas vaginalis sensory transduction histidine kinase, putative 0.0012 0.0005 0.0038
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0127 0.0126 0.1805
Brugia malayi heat shock protein 90 0.0059 0.0055 0.0768
Trichomonas vaginalis PIKK family atypical protein kinase 0.0662 0.0689 1
Trypanosoma cruzi DNA topoisomerase II, putative 0.0012 0.0005 0.0008
Echinococcus granulosus neuropeptide FF receptor 2 0.0052 0.0047 0.0047
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0127 0.0126 0.1805
Echinococcus multilocularis Pleckstrin G protein, interacting region 0.0009 0.0002 0.0002
Onchocerca volvulus 0.0127 0.0126 0.6529
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0662 0.0689 0.1969
Trichomonas vaginalis PIKK family atypical protein kinase 0.0662 0.0689 1
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0127 0.0126 0.0355
Schistosoma mansoni neuropeptide receptor 0.0052 0.0047 0.0675
Mycobacterium tuberculosis Probable hydrolase 0.0038 0.0032 0.1122
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0047 0.0675
Schistosoma mansoni hypothetical protein 0.0048 0.0042 0.0615
Trichomonas vaginalis sensor histidine kinase, putative 0.0012 0.0005 0.0038
Trichomonas vaginalis PIKK family atypical protein kinase 0.0662 0.0689 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0373 0.0385 0.5576
Echinococcus granulosus allatostatin A receptor 0.0052 0.0047 0.0047
Echinococcus granulosus biogenic amine 5HT receptor 0.0052 0.0047 0.0047
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0012 0.0005 0.0042
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.001 0.0002 0.0006
Echinococcus multilocularis heat shock protein 0.0059 0.0055 0.0055
Trypanosoma cruzi heat shock protein 85, putative 0.0059 0.0055 0.015
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0416 0.043 0.6231
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0373 0.0385 0.1098
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0127 0.0126 0.1805
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.019 0.0192 1
Toxoplasma gondii heat shock protein 75, putative 0.0024 0.0018 0.0229
Brugia malayi hypothetical protein 0.0052 0.0047 0.065
Echinococcus granulosus neuropeptides capa receptor 0.0052 0.0047 0.0047
Treponema pallidum chemotaxis histidine kinase (cheA) 0.0012 0.0005 0.0661
Loa Loa (eye worm) hypothetical protein 0.0052 0.0047 0.0649
Trichomonas vaginalis PIKK family atypical protein kinase 0.0127 0.0126 0.1805
Schistosoma mansoni heat shock protein 0.0059 0.0055 0.0792
Trichomonas vaginalis PIKK family atypical protein kinase 0.0662 0.0689 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0002 0.0004
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0127 0.0126 0.1805
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0048 0.0042 0.0042
Trichomonas vaginalis heat shock protein, putative 0.0036 0.003 0.0411
Plasmodium vivax DNA gyrase subunit B, putative 0.0012 0.0005 0.0211
Toxoplasma gondii histone lysine methyltransferase SET1 0.0057 0.0052 0.0735
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0373 0.0385 0.5576
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0012 0.0005 0.0008
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0127 0.0126 0.1808
Loa Loa (eye worm) hypothetical protein 0.0052 0.0047 0.0649
Echinococcus multilocularis serotonin receptor 0.0052 0.0047 0.0047
Mycobacterium leprae Probable lipase LipE 0.0038 0.0032 0.2404
Echinococcus multilocularis serine protein kinase ATM 0.0373 0.0385 0.0385
Schistosoma mansoni hypothetical protein 0.0048 0.0042 0.0615
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0067 0.0062 0.0879
Loa Loa (eye worm) phosphatidylinositol 3 0.0127 0.0126 0.1808
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0127 0.0126 0.1805
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0127 0.0126 0.0126
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0032 0.0465
Schistosoma mansoni biogenic amine (5HT) receptor 0.0052 0.0047 0.0675
Echinococcus multilocularis neuropeptide receptor A26 0.0052 0.0047 0.0047
Echinococcus granulosus tm gpcr rhodopsin 0.0052 0.0047 0.0047
Echinococcus granulosus tachykinin peptides receptor 99D 0.0052 0.0047 0.0047
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0052 0.0047 0.0047
Schistosoma mansoni pyruvate dehydrogenase 0.0012 0.0005 0.007
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0127 0.0126 0.1805
Trichomonas vaginalis DNA topoisomerase II, putative 0.0012 0.0005 0.0038
Loa Loa (eye worm) endoplasmin 0.0059 0.0055 0.0766
Echinococcus granulosus rhodopsin orphan GPCR 0.0052 0.0047 0.0047
Mycobacterium leprae conserved hypothetical protein 0.0038 0.0032 0.2404
Onchocerca volvulus 0.0048 0.0043 0.2151
Mycobacterium tuberculosis Conserved protein 0.0038 0.0032 0.1122
Echinococcus granulosus tar DNA binding protein 0.0067 0.0062 0.0062
Loa Loa (eye worm) heat shock protein 75 0.0024 0.0018 0.0229
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0151 0.0151 0.2171
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0052 0.0047 0.0675
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0052 0.0047 0.0047
Schistosoma mansoni hypothetical protein 0.0048 0.0042 0.0615
Trypanosoma cruzi heat shock protein 90, putative 0.0047 0.0042 0.0114
Loa Loa (eye worm) hypothetical protein 0.0052 0.0047 0.0649
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0052 0.0047 0.0047
Trichomonas vaginalis PIKK family atypical protein kinase 0.0373 0.0385 0.5576
Echinococcus granulosus regulator of G protein signaling 7 0.0009 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0052 0.0047 0.0649
Loa Loa (eye worm) hypothetical protein 0.0127 0.0126 0.1808
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.004 0.0584
Loa Loa (eye worm) hypothetical protein 0.0052 0.0047 0.0649
Plasmodium falciparum DNA topoisomerase 2 0.0012 0.0005 0.0211
Loa Loa (eye worm) TYRA-2 protein 0.0052 0.0047 0.0649
Echinococcus multilocularis nibrin 0.001 0.0002 0.0002
Echinococcus multilocularis g protein coupled receptor 0.0052 0.0047 0.0047
Brugia malayi beta-lactamase family protein 0.0038 0.0032 0.0439
Loa Loa (eye worm) neuropeptide F receptor 0.0052 0.0047 0.0649
Brugia malayi Serotonin receptor 0.0052 0.0047 0.065
Brugia malayi DIX domain containing protein 0.0009 0.0002 0.0002
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0052 0.0047 0.0675
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0038 0.0032 0.7515
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0289 0.0296 0.0296
Trypanosoma brucei heat shock protein, putative 0.0059 0.0055 0.0763
Onchocerca volvulus 0.0127 0.0126 0.6529
Loa Loa (eye worm) hypothetical protein 0.0052 0.0047 0.0649
Loa Loa (eye worm) hypothetical protein 0.0038 0.0032 0.0438
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0662 0.0689 0.189
Loa Loa (eye worm) hypothetical protein 0.0048 0.0042 0.0588
Echinococcus granulosus dro:myosuppressin receptor 0.0052 0.0047 0.0047
Trypanosoma brucei heat shock protein, putative 0.0059 0.0055 0.0763
Trichomonas vaginalis conserved hypothetical protein 0.0416 0.043 0.6229
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0052 0.0047 0.0649
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.001 0.0002 0.00000041562
Loa Loa (eye worm) hypothetical protein 0.0052 0.0047 0.0649
Schistosoma mansoni dep domain containing protein 0.0009 0.0002 0.0028
Trypanosoma cruzi heat shock protein, putative 0.0024 0.0018 0.0044
Onchocerca volvulus 0.0052 0.0047 0.2342
Echinococcus granulosus orexin receptor type 2 0.0052 0.0047 0.0047
Echinococcus granulosus beta LACTamase domain containing family member 0.0038 0.0032 0.0032
Trichomonas vaginalis PIKK family atypical protein kinase 0.0373 0.0385 0.5576
Loa Loa (eye worm) hypothetical protein 0.0052 0.0047 0.0649
Toxoplasma gondii heat shock protein 90, putative 0.0059 0.0055 0.0766
Trypanosoma brucei DNA topoisomerase ii 0.0012 0.0005 0.0038
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.004 0.004
Echinococcus multilocularis rhodopsin orphan GPCR 0.0052 0.0047 0.0047
Echinococcus granulosus regulator of G protein signaling 7 0.0009 0.0002 0.0002
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0032 0.2404
Trichomonas vaginalis heat shock protein, putative 0.0047 0.0042 0.0577
Loa Loa (eye worm) hypothetical protein 0.0052 0.0047 0.0649
Echinococcus granulosus rhodopsin orphan GPCR 0.0052 0.0047 0.0047
Plasmodium vivax heat shock protein 90, putative 0.0024 0.0018 0.125
Schistosoma mansoni opsin-like receptor 0.0052 0.0047 0.0675
Mycobacterium leprae Probable two-component sensor kinase 0.0012 0.0005 0.0211
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0127 0.0126 0.0126
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0662 0.0689 1
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.0032 0.0434
Trichomonas vaginalis PIKK family atypical protein kinase 0.0662 0.0689 1
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0127 0.0126 0.1805
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0012 0.0005 0.0151
Leishmania major phosphatidylinositol kinase related protein, putative 0.0127 0.0126 0.0335
Echinococcus multilocularis rhodopsin orphan GPCR 0.0052 0.0047 0.0047
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0032 0.0085
Mycobacterium ulcerans esterase/lipase LipP 0.0038 0.0032 0.7515
Loa Loa (eye worm) TOPoisomerase family member 0.0012 0.0005 0.0042
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0052 0.0047 0.0047
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0127 0.0126 0.1831
Entamoeba histolytica protein kinase rad3, putative 0.0373 0.0385 0.5576
Mycobacterium leprae TWO COMPONENT SENSOR HISTIDINE KINASE PRRB 0.0012 0.0005 0.0211
Brugia malayi N-terminal motif family protein 0.019 0.0192 0.2771
Onchocerca volvulus 0.0038 0.0032 0.158
Trypanosoma brucei heat shock protein, putative 0.0059 0.0055 0.0763
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0052 0.0047 0.0675
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0289 0.0296 0.0296
Leishmania major phosphatidylinositol 4-kinase, putative 0.0127 0.0126 0.0335
Loa Loa (eye worm) phosphatidylinositol 3 0.0662 0.0689 1
Wolbachia endosymbiont of Brugia malayi signal transduction histidine kinase and receiver 0.0012 0.0005 0.0661
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0662 0.0689 1
Brugia malayi topoisomerase 0.001 0.0002 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0662 0.0689 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0032 0.0438
Brugia malayi neuropeptide F receptor 0.0052 0.0047 0.065
Echinococcus granulosus transient receptor potential ion channel A 0.0099 0.0096 0.0096
Leishmania major phosphatidylinositol 3-kinase, putative 0.0127 0.0126 0.0335
Echinococcus multilocularis rhodopsin orphan GPCR 0.0052 0.0047 0.0047
Toxoplasma gondii heat shock protein HSP90 0.0059 0.0055 0.0766
Loa Loa (eye worm) hypothetical protein 0.019 0.0192 0.277
Schistosoma mansoni hypothetical protein 0.0127 0.0126 0.1831
Schistosoma mansoni amine GPCR 0.0052 0.0047 0.0675
Plasmodium falciparum endoplasmin, putative 0.0036 0.003 0.2277
Brugia malayi beta-lactamase family protein 0.0038 0.0032 0.0439
Echinococcus multilocularis G protein coupled receptor 139 0.0052 0.0047 0.0047
Echinococcus multilocularis tumor protein p63 0.0329 0.0339 0.0339
Echinococcus granulosus Pleckstrin G protein interacting region 0.0009 0.0002 0.0002
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0038 0.0032 0.0438
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0038 0.0032 0.0032
Plasmodium vivax DNA topoisomerase II, putative 0.0012 0.0005 0.0211
Loa Loa (eye worm) hypothetical protein 0.0102 0.01 0.1423
Brugia malayi ORL1-like opioid receptor 0.0052 0.0047 0.065
Trypanosoma cruzi developmentally regulated phosphoprotein, putative 0.0012 0.0005 0.0008
Schistosoma mansoni hypothetical protein 0.0048 0.0042 0.0615
Loa Loa (eye worm) hypothetical protein 0.0052 0.0047 0.0649
Loa Loa (eye worm) hypothetical protein 0.0038 0.0032 0.0438
Giardia lamblia Hypothetical protein 0.0127 0.0126 0.1805
Brugia malayi Melatonin receptor type 1A 0.0052 0.0047 0.065
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0012 0.0005 0.0008
Echinococcus granulosus rhodopsin orphan GPCR 0.0052 0.0047 0.0047
Toxoplasma gondii target of rapamycin (TOR), putative 0.0662 0.0689 1
Plasmodium falciparum heat shock protein 90, putative 0.0024 0.0018 0.125
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0373 0.0385 0.0385
Echinococcus multilocularis tar DNA binding protein 0.0067 0.0062 0.0062
Echinococcus granulosus neuropeptide receptor 0.0052 0.0047 0.0047
Mycobacterium ulcerans two component sensor histidine kinase TrcS 0.0012 0.0005 0.0661
Plasmodium vivax hypothetical protein, conserved 0.0012 0.0005 0.0211
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0047 0.0042 0.0042
Trypanosoma brucei heat shock protein, putative 0.0059 0.0055 0.0763
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0052 0.0047 0.0047
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0127 0.0126 0.0355
Trichomonas vaginalis heat shock protein, putative 0.0047 0.0042 0.0577
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0052 0.0047 0.0047
Trichomonas vaginalis PIKK family atypical protein kinase 0.0662 0.0689 1
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0052 0.0047 0.0649
Entamoeba histolytica hypothetical protein 0.0127 0.0126 0.1805
Schistosoma mansoni histamine h1 receptor 0.0052 0.0047 0.0675
Mycobacterium tuberculosis Conserved protein 0.0038 0.0032 0.1122
Loa Loa (eye worm) hypothetical protein 0.0052 0.0047 0.0649
Echinococcus multilocularis dro:myosuppressin receptor 0.0052 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0012 0.0005 0.0042
Echinococcus granulosus rhodopsin orphan GPCR 0.0052 0.0047 0.0047
Trichomonas vaginalis PIKK family atypical protein kinase 0.0373 0.0385 0.5576
Schistosoma mansoni heat shock protein 0.0059 0.0055 0.0792
Trichomonas vaginalis PIKK family atypical protein kinase 0.0662 0.0689 1
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0127 0.0126 0.1805
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0127 0.0126 0.1805
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0052 0.0047 0.065
Onchocerca volvulus 0.0052 0.0047 0.2342
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0127 0.0126 0.1805
Brugia malayi Tachykinin-like peptides receptor 99D 0.0052 0.0047 0.065
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0012 0.0005 0.0005
Echinococcus multilocularis beta LACTamase domain containing family member 0.0038 0.0032 0.0032
Trichomonas vaginalis PIKK family atypical protein kinase 0.0662 0.0689 1
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0127 0.0126 0.1805
Loa Loa (eye worm) hypothetical protein 0.0052 0.0047 0.0649
Entamoeba histolytica hypothetical protein 0.0373 0.0385 0.5576
Echinococcus granulosus neuropeptide s receptor 0.0052 0.0047 0.0047
Brugia malayi hypothetical protein 0.0009 0.0002 0.0002
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0052 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0052 0.0047 0.0649
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0052 0.0047 0.0047
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0012 0.0005 0.0005
Onchocerca volvulus Neuropeptide F receptor homolog 0.0052 0.0047 0.2342
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0127 0.0126 0.0355
Loa Loa (eye worm) phosphatidylinositol 3 0.0127 0.0126 0.1808
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0052 0.0047 0.0649
Schistosoma mansoni DNA topoisomerase II 0.0012 0.0005 0.007
Loa Loa (eye worm) phosphatidylinositol 3 0.0127 0.0126 0.1808
Trichomonas vaginalis PIKK family atypical protein kinase 0.0127 0.0126 0.1805
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0127 0.0126 0.1831
Leishmania major heat shock protein 83-1 0.0059 0.0055 0.0137
Echinococcus granulosus g-protein coupled receptor 0.0052 0.0047 0.0047
Onchocerca volvulus 0.0052 0.0047 0.2342
Trichomonas vaginalis PIKK family atypical protein kinase 0.0662 0.0689 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.004 0.004
Echinococcus granulosus segment polarity protein dishevelled 0.0009 0.0002 0.0002
Chlamydia trachomatis DNA gyrase subunit B 0.0012 0.0005 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0002 0.0004
Brugia malayi AKH receptor 0.0052 0.0047 0.065
Echinococcus granulosus alpha 1A adrenergic receptor 0.0052 0.0047 0.0047
Trypanosoma cruzi Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0012 0.0005 0.0008
Leishmania major heat shock protein 83-1 0.0059 0.0055 0.0137
Brugia malayi FAT domain containing protein 0.0289 0.0296 0.428
Schistosoma mansoni biogenic amine receptor 0.0052 0.0047 0.0675
Echinococcus multilocularis dnaJ subfamily B 0.0431 0.0446 0.0446
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0127 0.0126 0.1805
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0048 0.0042 0.0042
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0127 0.0126 0.0335
Trichomonas vaginalis PIKK family atypical protein kinase 0.0373 0.0385 0.5576
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0127 0.0126 0.181
Loa Loa (eye worm) hypothetical protein 0.0012 0.0005 0.0042
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0052 0.0047 0.0675
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0032 0.0465
Leishmania major heat shock protein 83-1 0.0059 0.0055 0.0137
Loa Loa (eye worm) phosphatidylinositol 3 0.0127 0.0126 0.1808
Brugia malayi hypothetical protein 0.0052 0.0047 0.065
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0047 0.0042 0.1529
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0052 0.0047 0.0047
Onchocerca volvulus 0.001 0.0002 0.0014
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0052 0.0047 0.0649
Schistosoma mansoni z-protein (S1r protein) 0.0009 0.0002 0.0028
Trichomonas vaginalis receptor histidine kinase, putative 0.0012 0.0005 0.0038
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.0127 0.0126 0.0126
Trichomonas vaginalis PIKK family atypical protein kinase 0.0246 0.0251 0.3623
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0047 0.0675
Loa Loa (eye worm) hypothetical protein 0.0052 0.0047 0.0649
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0024 0.0018 0.0018
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0047 0.0675
Leishmania major heat shock protein 83-1 0.0059 0.0055 0.0137
Schistosoma mansoni topbp1 0.001 0.0002 0.0032
Leishmania major heat shock protein 83-1 0.0059 0.0055 0.0137
Echinococcus multilocularis g protein coupled receptor 0.0052 0.0047 0.0047
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0127 0.0126 0.1831
Loa Loa (eye worm) hypothetical protein 0.0052 0.0047 0.0649
Echinococcus granulosus transient receptor potential gamma protein 0.0102 0.01 0.01
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0052 0.0047 0.0649
Trichomonas vaginalis heat shock protein, putative 0.0024 0.0018 0.0226
Loa Loa (eye worm) hypothetical protein 0.0052 0.0047 0.0649
Echinococcus multilocularis short transient receptor potential channel 6 0.0068 0.0063 0.0063
Trypanosoma brucei heat shock protein, putative 0.0059 0.0055 0.0763
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0052 0.0047 0.0047
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0052 0.0047 0.0047
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.004 0.0584
Entamoeba histolytica heat shock protein 90, putative 0.0059 0.0055 0.0763
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0127 0.0126 0.1805
Leishmania major hypothetical protein, conserved 0.345 0.3627 1
Trypanosoma cruzi Heat shock protein 83, putative 0.0059 0.0055 0.015
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0127 0.0126 0.1831
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.004 0.004
Plasmodium vivax hypothetical protein 0.0127 0.0126 1
Toxoplasma gondii ATPase, AAA family protein 0.001 0.0002 0.0004
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0662 0.0689 1
Brugia malayi GnHR receptor homolog 0.0052 0.0047 0.065
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0052 0.0047 0.0047
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0062 0.0904
Loa Loa (eye worm) hypothetical protein 0.0052 0.0047 0.0649
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0047 0.0042 0.0102
Schistosoma mansoni amine GPCR 0.0052 0.0047 0.0675
Schistosoma mansoni biogenic amine (5HT) receptor 0.0052 0.0047 0.0675
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.0127 0.0126 0.1805
Leishmania major heat shock protein, putative 0.0024 0.0018 0.0036
Trichomonas vaginalis PIKK family atypical protein kinase 0.0662 0.0689 1
Schistosoma mansoni amine GPCR 0.0052 0.0047 0.0675
Treponema pallidum heat shock protein 90 0.0047 0.0042 1
Leishmania major heat shock protein 83-1 0.0059 0.0055 0.0137
Echinococcus granulosus endoplasmin 0.0047 0.0042 0.0042
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0127 0.0126 1
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0127 0.0126 0.1805
Echinococcus multilocularis short transient receptor potential channel 6 0.0068 0.0063 0.0063
Echinococcus granulosus rhodopsin orphan GPCR 0.0052 0.0047 0.0047
Echinococcus multilocularis neuropeptide FF receptor 2 0.0052 0.0047 0.0047
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0012 0.0005 0.0038
Brugia malayi G-protein coupled receptor 0.0052 0.0047 0.065
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0127 0.0126 0.0126
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0032 0.0434
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.0127 0.0126 1
Echinococcus multilocularis neuropeptides capa receptor 0.0052 0.0047 0.0047
Trypanosoma cruzi heat shock protein 90, putative 0.0059 0.0055 0.015
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0662 0.0689 0.0689
Echinococcus granulosus biogenic amine 5HT receptor 0.0052 0.0047 0.0047
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0127 0.0126 0.0126
Echinococcus granulosus replication factor c subunit 1 0.001 0.0002 0.0002
Entamoeba histolytica hypothetical protein 0.0127 0.0126 0.1805
Echinococcus granulosus tm gpcr rhodopsin 0.0052 0.0047 0.0047
Trichomonas vaginalis PIKK family atypical protein kinase 0.0662 0.0689 1
Echinococcus multilocularis neuropeptide Y receptor 0.0052 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0052 0.0047 0.0649
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0052 0.0047 0.0675
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0662 0.0689 0.1969
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0127 0.0126 0.1805
Brugia malayi Calcitonin receptor-like protein seb-1 0.0151 0.0151 0.2171
Loa Loa (eye worm) hypothetical protein 0.001 0.0002 0.0004
Brugia malayi RNA recognition motif domain containing protein 0.0067 0.0062 0.088
Onchocerca volvulus 0.0052 0.0047 0.2342
Schistosoma mansoni amine GPCR 0.0052 0.0047 0.0675
Mycobacterium ulcerans DNA gyrase subunit B 0.0012 0.0005 0.0661
Schistosoma mansoni hypothetical protein 0.0052 0.0047 0.0675
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0032 0.0434
Brugia malayi regulator of G-protein signaling egl-10 0.0009 0.0002 0.0002
Onchocerca volvulus 0.0038 0.0032 0.158
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0046 0.004 0.0559
Giardia lamblia Heat shock protein HSP 90-alpha 0.0059 0.0055 0.0763
Echinococcus multilocularis neuropeptide receptor 0.0052 0.0047 0.0047
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0127 0.0126 0.0126
Echinococcus granulosus segment polarity protein dishevelled 0.0009 0.0002 0.0002
Schistosoma mansoni endoplasmin 0.0059 0.0055 0.0792
Loa Loa (eye worm) hypothetical protein 0.0052 0.0047 0.0649
Schistosoma mansoni neuropeptide receptor 0.0052 0.0047 0.0675
Echinococcus granulosus 7tm_1 domain containing protein 0.0052 0.0047 0.0047
Brugia malayi Latrophilin receptor protein 2 0.0048 0.0042 0.059
Echinococcus granulosus neuropeptide Y receptor 0.0052 0.0047 0.0047
Schistosoma mansoni hypothetical protein 0.0169 0.017 0.2472
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0127 0.0126 0.1831
Loa Loa (eye worm) histone methyltransferase 0.0009 0.0002 0.00000061534
Giardia lamblia Phosphatidylinositol 4-kinase 0.0127 0.0126 0.1805
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0662 0.0689 0.1969
Schistosoma mansoni transient receptor potential channel 0.0068 0.0063 0.0918
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0064 0.006 0.0865
Echinococcus granulosus GPCR family 2 0.0048 0.0042 0.0042
Leishmania major heat shock protein 83-1 0.0059 0.0055 0.0137
Echinococcus granulosus tm gpcr rhodopsin 0.0052 0.0047 0.0047
Echinococcus multilocularis orexin receptor type 2 0.0052 0.0047 0.0047
Mycobacterium ulcerans two component system membrane associated sensor kinase 0.0012 0.0005 0.0661
Loa Loa (eye worm) beta-lactamase 0.0038 0.0032 0.0438
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0127 0.0126 0.0126
Mycobacterium ulcerans two component regulator - sensor kinase 0.0012 0.0005 0.0661
Loa Loa (eye worm) hypothetical protein 0.0035 0.0029 0.0387
Trichomonas vaginalis PIKK family atypical protein kinase 0.0662 0.0689 1
Leishmania major hypothetical protein, conserved 0.0038 0.0032 0.0075
Leishmania major phosphatidylinositol 3-kinase, putative 0.0662 0.0689 0.189
Echinococcus granulosus peptide allatostatin:somatostatin 0.0052 0.0047 0.0047
Onchocerca volvulus 0.0052 0.0047 0.2342
Loa Loa (eye worm) hypothetical protein 0.0052 0.0047 0.0649
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0052 0.0047 0.065
Brugia malayi hypothetical protein 0.0009 0.0002 0.0002
Echinococcus multilocularis endoplasmin 0.0047 0.0042 0.0042
Onchocerca volvulus 0.0052 0.0047 0.2342
Leishmania major heat shock protein 83-1 0.0059 0.0055 0.0137
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0032 0.0434
Trypanosoma brucei developmentally regulated phosphoprotein 0.0012 0.0005 0.0038
Loa Loa (eye worm) hypothetical protein 0.0151 0.0151 0.2169
Mycobacterium ulcerans lipase LipD 0.0038 0.0032 0.7515
Leishmania major heat shock protein 83-1 0.0059 0.0055 0.0137
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.9499 1 1
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0127 0.0126 0.0126
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0052 0.0047 0.0675
Trypanosoma cruzi heat shock protein 90, putative 0.0035 0.0029 0.0077
Echinococcus granulosus short transient receptor potential channel 6 0.0068 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0052 0.0047 0.0649
Trichomonas vaginalis receptor histidine kinase, putative 0.0012 0.0005 0.0038
Onchocerca volvulus 0.0052 0.0047 0.2342
Trichomonas vaginalis PIKK family atypical protein kinase 0.0662 0.0689 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0032 0.0439
Schistosoma mansoni neuropeptide receptor 0.0052 0.0047 0.0675
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0242 0.0247 1
Echinococcus multilocularis transient receptor potential ion channel A 0.0099 0.0096 0.0096
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.001 0.0002 0.00000041562
Echinococcus granulosus geminin 0.0169 0.017 0.017
Trichomonas vaginalis two component sensor and regulator histidine kinase bacteria, putative 0.0012 0.0005 0.0038
Loa Loa (eye worm) hypothetical protein 0.0038 0.0032 0.0438
Brugia malayi Dopamine receptor protein 2 0.0052 0.0047 0.065
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0127 0.0126 0.0355
Trypanosoma brucei heat shock protein, putative 0.0059 0.0055 0.0763
Schistosoma mansoni opsin-like receptor 0.0052 0.0047 0.0675
Loa Loa (eye worm) hypothetical protein 0.0052 0.0047 0.0649
Echinococcus granulosus hypothetical protein 0.0052 0.0047 0.0047
Trichomonas vaginalis PIKK family atypical protein kinase 0.0662 0.0689 1
Mycobacterium ulcerans sensor kinase from two component regulatory system 0.0012 0.0005 0.0661
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0047 0.0675
Loa Loa (eye worm) hypothetical protein 0.0052 0.0047 0.0649
Trichomonas vaginalis PIKK family atypical protein kinase 0.0373 0.0385 0.5576
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0046 0.004 0.0557
Echinococcus multilocularis fmrfamide receptor 0.0052 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.001 0.0002 0.0004
Mycobacterium tuberculosis Probable esterase LipL 0.0038 0.0032 0.1122
Echinococcus granulosus G protein coupled receptor 139 0.0052 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0052 0.0047 0.0649
Brugia malayi hypothetical protein 0.0052 0.0047 0.065
Brugia malayi follicle stimulating hormone receptor 0.0052 0.0047 0.065
Schistosoma mansoni myosin xvIII 0.0052 0.0047 0.0675
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0127 0.0126 0.0355
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0127 0.0126 0.181
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0012 0.0005 0.0661
Loa Loa (eye worm) hypothetical protein 0.0052 0.0047 0.0649
Echinococcus granulosus neuropeptides capa receptor 0.0052 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0052 0.0047 0.0649
Echinococcus granulosus neuropeptide Y receptor 0.0052 0.0047 0.0047
Onchocerca volvulus 0.0052 0.0047 0.2342
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0127 0.0126 0.0355
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0052 0.0047 0.0675
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0038 0.0032 0.1122
Echinococcus granulosus cpg binding protein 0.0032 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0127 0.0126 0.1808
Trypanosoma cruzi DNA topoisomerase II, putative 0.0012 0.0005 0.0008
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0012 0.0005 0.0044
Loa Loa (eye worm) phosphatidylinositol 3 0.0662 0.0689 1
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0662 0.0689 0.0689
Plasmodium vivax endoplasmin, putative 0.0059 0.0055 0.4226
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0127 0.0126 0.1805
Echinococcus multilocularis Zinc finger, PHD finger 0.0127 0.0126 0.0126
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0012 0.0005 0.0661
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0052 0.0047 0.0047
Echinococcus granulosus rhodopsin orphan GPCR 0.0052 0.0047 0.0047
Trichomonas vaginalis PIKK family atypical protein kinase 0.0662 0.0689 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0373 0.0385 0.5576
Trypanosoma cruzi target of rapamycin kinase 3 0.0662 0.0689 0.1969
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0012 0.0005 0.0038
Mycobacterium leprae Probable two component sensor kinase MprB 0.0012 0.0005 0.0211
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0048 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0246 0.0251 0.3626
Loa Loa (eye worm) hypothetical protein 0.0052 0.0047 0.0649
Loa Loa (eye worm) hypothetical protein 0.0052 0.0047 0.0649
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0052 0.0047 0.0675
Giardia lamblia Grp94/Hsp90 0.0047 0.0042 0.0577
Trypanosoma brucei heat shock protein 90, putative 0.0059 0.0055 0.0763
Schistosoma mansoni hypothetical protein 0.0103 0.0101 0.1462
Trypanosoma cruzi heat shock protein 85, putative 0.0059 0.0055 0.015
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0052 0.0047 0.065
Schistosoma mansoni biogenic amine receptor 0.0052 0.0047 0.0675
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.004 0.004
Echinococcus multilocularis somatostatin receptor 0.0052 0.0047 0.0047
Brugia malayi TAR-binding protein 0.0067 0.0062 0.088
Echinococcus multilocularis heat shock protein 90 0.0047 0.0042 0.0042
Schistosoma mansoni neuropeptide receptor 0.0052 0.0047 0.0675
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.001 0.0002 0.00000041562
Echinococcus granulosus heat shock protein 90 0.0047 0.0042 0.0042
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0127 0.0126 0.1805
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0012 0.0005 0.0151
Echinococcus granulosus 7TM GPCR rhodopsin 0.0052 0.0047 0.0047
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0012 0.0005 0.0151
Brugia malayi Probable DNA topoisomerase II 0.0012 0.0005 0.0044
Echinococcus multilocularis segment polarity protein dishevelled 0.0009 0.0002 0.0002
Brugia malayi latrophilin 2 splice variant baaae 0.0103 0.0101 0.1439
Loa Loa (eye worm) G-protein coupled receptor 0.0052 0.0047 0.0649
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0032 0.0085
Loa Loa (eye worm) G-protein coupled receptor 0.0052 0.0047 0.0649
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0373 0.0385 0.5578
Echinococcus granulosus TRP transient receptor potential channel 0.0038 0.0032 0.0032
Echinococcus multilocularis regulator of G protein signaling 7 0.0009 0.0002 0.0002
Trypanosoma brucei heat shock protein, putative 0.0059 0.0055 0.0763
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0052 0.0047 0.2342
Echinococcus multilocularis sex peptide receptor 0.0052 0.0047 0.0047
Onchocerca volvulus 0.0052 0.0047 0.2342
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0038 0.0032 0.0439
Trichomonas vaginalis heat shock protein, putative 0.0059 0.0055 0.0763
Entamoeba histolytica DNA topoisomerase II, putative 0.0012 0.0005 0.0038
Toxoplasma gondii FATC domain-containing protein 0.0373 0.0385 0.5577
Leishmania major heat shock protein 83-1 0.0059 0.0055 0.0137
Trypanosoma cruzi heat shock protein 85, putative 0.0047 0.0042 0.0114
Trichomonas vaginalis PIKK family atypical protein kinase 0.0416 0.043 0.6229
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0246 0.0251 0.0713
Loa Loa (eye worm) RNA binding protein 0.0067 0.0062 0.0879
Brugia malayi Serotonin receptor 0.0052 0.0047 0.065
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0151 0.0151 0.2169
Echinococcus multilocularis replication factor c subunit 1 0.001 0.0002 0.0002
Echinococcus multilocularis 0.0127 0.0126 0.0126
Schistosoma mansoni amine GPCR 0.0052 0.0047 0.0675
Echinococcus granulosus heat shock protein 90 0.0059 0.0055 0.0055
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.001 0.0002 0.0004
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0127 0.0126 0.181
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0127 0.0126 0.1805
Trichomonas vaginalis PIKK family atypical protein kinase 0.0662 0.0689 1
Echinococcus multilocularis g protein coupled receptor 0.0052 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0012 0.0005 0.0042
Loa Loa (eye worm) hypothetical protein 0.0038 0.0032 0.0438
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0373 0.0385 0.1098
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0662 0.0689 1
Loa Loa (eye worm) hypothetical protein 0.0289 0.0296 0.4279
Trichomonas vaginalis PIKK family atypical protein kinase 0.0662 0.0689 1
Mycobacterium ulcerans two component sensor kinase MprB 0.0012 0.0005 0.0661
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0127 0.0126 0.1805
Brugia malayi neuropeptide F receptor 0.0052 0.0047 0.065
Echinococcus multilocularis fmrfamide receptor 0.0052 0.0047 0.0047
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0127 0.0126 0.1805
Loa Loa (eye worm) hypothetical protein 0.0038 0.0032 0.0438
Chlamydia trachomatis DNA gyrase subunit B 0.0012 0.0005 1
Echinococcus multilocularis geminin 0.0169 0.017 0.017
Schistosoma mansoni neuropeptide F-like receptor 0.0052 0.0047 0.0675
Loa Loa (eye worm) hypothetical protein 0.0052 0.0047 0.0649
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0127 0.0126 0.1805
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0052 0.0047 0.0675
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.004 0.0584
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0127 0.0126 1
Wolbachia endosymbiont of Brugia malayi membrane associated signal transduction histidine kinase 0.0012 0.0005 0.0661
Loa Loa (eye worm) hypothetical protein 0.0103 0.0101 0.1437
Onchocerca volvulus 0.0052 0.0047 0.2342
Brugia malayi putative neuropeptide receptor NPR1 0.0052 0.0047 0.065
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0662 0.0689 1
Echinococcus granulosus tumor protein p63 0.0329 0.0339 0.0339
Trichomonas vaginalis PIKK family atypical protein kinase 0.0662 0.0689 1
Echinococcus granulosus nibrin 0.001 0.0002 0.0002
Echinococcus multilocularis rhodopsin orphan GPCR 0.0052 0.0047 0.0047
Toxoplasma gondii DNA topoisomerase 2, putative 0.0012 0.0005 0.0042
Loa Loa (eye worm) neuropeptide F receptor 0.0052 0.0047 0.0649
Echinococcus multilocularis allatostatin A receptor 0.0052 0.0047 0.0047
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0662 0.0689 0.189
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0127 0.0126 0.181
Entamoeba histolytica hypothetical protein 0.0127 0.0126 0.1805
Echinococcus granulosus fmrfamide receptor 0.0052 0.0047 0.0047
Echinococcus granulosus neuropeptide receptor A26 0.0052 0.0047 0.0047
Brugia malayi putative neuropeptide receptor 0.0052 0.0047 0.065
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0127 0.0126 0.1805
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.0012 0.0005 0.0005
Schistosoma mansoni transient receptor potential channel 4 0.0102 0.01 0.1447
Schistosoma mansoni hypothetical protein 0.0169 0.017 0.2472
Trichomonas vaginalis conserved hypothetical protein 0.0246 0.0251 0.3623
Schistosoma mansoni cpg binding protein 0.003 0.0024 0.0347
Echinococcus granulosus serine protein kinase ATM 0.0373 0.0385 0.0385
Trichomonas vaginalis PIKK family atypical protein kinase 0.0662 0.0689 1
Echinococcus granulosus short transient receptor potential channel 6 0.0068 0.0063 0.0063
Plasmodium vivax heat shock protein 86, putative 0.0059 0.0055 0.4226
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0127 0.0126 0.0355
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0052 0.0047 0.0047
Schistosoma mansoni chromosome transmission fidelity factor 0.001 0.0002 0.0032
Schistosoma mansoni biogenic amine receptor 0.0052 0.0047 0.0675
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0127 0.0126 0.1805
Loa Loa (eye worm) TAR-binding protein 0.0067 0.0062 0.0879
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0024 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0052 0.0047 0.0649
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0127 0.0126 0.1808
Leishmania major heat shock protein 83-1 0.0059 0.0055 0.0137
Trypanosoma cruzi heat shock protein 85, putative 0.0059 0.0055 0.015
Loa Loa (eye worm) hypothetical protein 0.001 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0052 0.0047 0.0649
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0373 0.0385 0.5578
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0043 0.0622
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0791 0.0825 0.0825
Loa Loa (eye worm) hypothetical protein 0.0048 0.0043 0.0596
Schistosoma mansoni DNA ligase IV 0.001 0.0002 0.0032
Onchocerca volvulus 0.0052 0.0047 0.2342
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0373 0.0385 0.559
Schistosoma mansoni fyve finger-containing phosphoinositide kinase fyv1 0.0009 0.0002 0.0028
Schistosoma mansoni regulator of G protein signaling 0.0009 0.0002 0.0028
Trichomonas vaginalis PIKK family atypical protein kinase 0.0662 0.0689 1
Echinococcus granulosus serotonin receptor 0.0052 0.0047 0.0047
Trichomonas vaginalis PIKK family atypical protein kinase 0.0662 0.0689 1
Brugia malayi kinase, mitochondrial precursor 0.0012 0.0005 0.0044
Echinococcus multilocularis neuropeptide receptor 0.0052 0.0047 0.0047
Echinococcus multilocularis transient receptor potential gamma protein 0.0102 0.01 0.01
Trypanosoma brucei heat shock protein 84, putative 0.0024 0.0018 0.0226
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0127 0.0126 0.1805
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.0127 0.0126 1
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0127 0.0126 0.1831
Leishmania major heat shock protein 83-1 0.0059 0.0055 0.0137
Schistosoma mansoni hypothetical protein 0.0052 0.0047 0.0675
Brugia malayi CXXC zinc finger family protein 0.003 0.0024 0.0322
Schistosoma mansoni transient receptor potential channel 0.0068 0.0063 0.0918
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0062 0.0904
Brugia malayi sulfakinin receptor protein 0.0052 0.0047 0.065
Loa Loa (eye worm) hypothetical protein 0.0416 0.043 0.6231
Brugia malayi beta-lactamase 0.0038 0.0032 0.0439
Loa Loa (eye worm) hypothetical protein 0.0052 0.0047 0.0649
Loa Loa (eye worm) melatonin receptor type 1A 0.0052 0.0047 0.0649
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0047 0.0675
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0062 0.0904
Onchocerca volvulus 0.0052 0.0047 0.2342
Brugia malayi hypothetical protein 0.0052 0.0047 0.065
Echinococcus multilocularis rhodopsin orphan GPCR 0.0052 0.0047 0.0047
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0047 0.0675
Loa Loa (eye worm) hypothetical protein 0.0373 0.0385 0.5577
Mycobacterium tuberculosis Probable lipase LipD 0.0038 0.0032 0.1122
Brugia malayi RE15519p 0.0052 0.0047 0.065
Onchocerca volvulus 0.0052 0.0047 0.2342
Trichomonas vaginalis conserved hypothetical protein 0.0289 0.0296 0.4277
Mycobacterium ulcerans putative regultory protein 0.0012 0.0005 0.0661
Loa Loa (eye worm) hypothetical protein 0.001 0.0002 0.0004
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.0002 0.0002
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0024 0.0018 0.0828
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0127 0.0126 0.1808
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0662 0.0689 1
Onchocerca volvulus 0.003 0.0024 0.1156
Schistosoma mansoni opsin-like receptor 0.0052 0.0047 0.0675
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0012 0.0005 0.0005
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0662 0.0689 1
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0052 0.0047 0.0047
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0662 0.0689 0.0689
Trichomonas vaginalis endoplasmin, putative 0.0036 0.003 0.0411
Echinococcus granulosus somatostatin receptor 0.0052 0.0047 0.0047
Brugia malayi hypothetical protein 0.001 0.0002 0.0006
Echinococcus multilocularis neuropeptides capa receptor 0.0052 0.0047 0.0047
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.0127 0.0126 0.0355
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0024 0.032
Leishmania major heat shock protein 83-1 0.0059 0.0055 0.0137
Leishmania major heat shock protein 83-1 0.0059 0.0055 0.0137
Echinococcus granulosus sex peptide receptor 0.0052 0.0047 0.0047
Mycobacterium tuberculosis Conserved protein 0.0038 0.0032 0.1122
Trichomonas vaginalis PIKK family atypical protein kinase 0.0662 0.0689 1
Loa Loa (eye worm) hypothetical protein 0.0052 0.0047 0.0649
Brugia malayi hypothetical protein 0.0052 0.0047 0.065
Onchocerca volvulus 0.0038 0.0032 0.158
Schistosoma mansoni neuropeptide F-like receptor 0.0052 0.0047 0.0675
Schistosoma mansoni neuropeptide f receptor 76f 0.0052 0.0047 0.0675
Loa Loa (eye worm) hypothetical protein 0.0064 0.006 0.084
Trichomonas vaginalis PIKK family atypical protein kinase 0.0662 0.0689 1
Brugia malayi G protein-coupled receptor 0.0052 0.0047 0.065
Brugia malayi G-protein coupled receptor 0.0052 0.0047 0.065
Brugia malayi hypothetical protein 0.001 0.0002 0.0006
Plasmodium falciparum DNA topoisomerase VI, b subunit, putative 0.0012 0.0005 0.0211
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0012 0.0005 1
Loa Loa (eye worm) hypothetical protein 0.0052 0.0047 0.0649
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0127 0.0126 0.181
Onchocerca volvulus 0.0052 0.0047 0.2342
Loa Loa (eye worm) hypothetical protein 0.0052 0.0047 0.0649
Schistosoma mansoni hypothetical protein 0.0052 0.0047 0.0675
Brugia malayi hypothetical protein 0.0052 0.0047 0.065
Loa Loa (eye worm) heat shock protein 90 0.0059 0.0055 0.0766
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0127 0.0126 0.0126
Leishmania major heat shock protein 83-1 0.0059 0.0055 0.0137
Schistosoma mansoni topbp1 0.001 0.0002 0.0032
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0052 0.0047 0.065
Trichomonas vaginalis PIKK family atypical protein kinase 0.0662 0.0689 1
Onchocerca volvulus 0.0052 0.0047 0.2342
Loa Loa (eye worm) hypothetical protein 0.0052 0.0047 0.0649
Echinococcus granulosus g protein coupled receptor 0.0052 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0052 0.0047 0.0649
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0012 0.0005 0.0042
Echinococcus multilocularis heat shock protein 90 0.0059 0.0055 0.0055
Brugia malayi Dopamine receptor protein 1 0.0052 0.0047 0.065
Echinococcus multilocularis neuropeptide s receptor 0.0052 0.0047 0.0047
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0012 0.0005 0.0038
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0032 0.0434
Brugia malayi larval opioid receptor 0.0052 0.0047 0.065
Mycobacterium ulcerans beta-lactamase 0.0038 0.0032 0.7515
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0052 0.0047 0.0047
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0127 0.0126 0.181
Echinococcus granulosus g protein coupled receptor 0.0052 0.0047 0.0047
Schistosoma mansoni alpha-1 adrenergic receptor 0.0052 0.0047 0.0675
Giardia lamblia Pms1-like protein 0.0012 0.0005 0.0038
Mycobacterium ulcerans two component system response phosphate sensor kinase, PhoR 0.0012 0.0005 0.0661
Echinococcus multilocularis G-protein coupled receptor, putative 0.0052 0.0047 0.0047
Trypanosoma brucei heat shock protein, putative 0.0059 0.0055 0.0763
Mycobacterium ulcerans hypothetical protein 0.0038 0.0032 0.7515
Loa Loa (eye worm) hypothetical protein 0.0052 0.0047 0.0649
Leishmania major hypothetical protein, unknown function 0.0127 0.0126 0.0335
Mycobacterium tuberculosis Probable lipase LipE 0.0038 0.0032 0.1122
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.0127 0.0126 0.1805
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0012 0.0005 0.0005
Echinococcus multilocularis g-protein coupled receptor 0.0052 0.0047 0.0047
Echinococcus multilocularis neuropeptide Y receptor 0.0052 0.0047 0.0047
Brugia malayi Hsp90 protein 0.0024 0.0018 0.0231
Loa Loa (eye worm) hypothetical protein 0.0052 0.0047 0.0649
Brugia malayi hypothetical protein 0.0052 0.0047 0.065
Trichomonas vaginalis heat shock protein, putative 0.0047 0.0042 0.0577
Schistosoma mansoni hypothetical protein 0.0289 0.0296 0.4295
Entamoeba histolytica hypothetical protein 0.0127 0.0126 0.1805
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0662 0.0689 0.189
Echinococcus granulosus dnaJ subfamily B 0.0431 0.0446 0.0446
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0048 0.0042 0.059
Schistosoma mansoni heat shock protein 0.0024 0.0018 0.0257
Loa Loa (eye worm) hypothetical protein 0.0052 0.0047 0.0649
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0127 0.0126 0.1808
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0038 0.0032 0.1122
Mycobacterium ulcerans two component sensor histidine kinase SenX3 0.0012 0.0005 0.0661
Schistosoma mansoni hypothetical protein 0.0052 0.0047 0.0675
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0662 0.0689 1
Trypanosoma brucei Heat shock protein 83, putative 0.0059 0.0055 0.0763
Trichomonas vaginalis replication factor C large subunit, putative 0.001 0.0002 0.00000041562

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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