Detailed information for compound 672754

Basic information

Technical information
  • TDR Targets ID: 672754
  • Name: T5265152
  • MW: 333.261 | Formula: C17H10F3NO3
  • H donors: 1 H acceptors: 2 LogP: 3.47 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(c1cc(=O)c2c(o1)cccc2)Nc1cccc(c1)C(F)(F)F
  • InChi: 1S/C17H10F3NO3/c18-17(19,20)10-4-3-5-11(8-10)21-16(23)15-9-13(22)12-6-1-2-7-14(12)24-15/h1-9H,(H,21,23)
  • InChiKey: FCYURHROHKYHLY-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • ZINC02626097

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) MH2 domain-containing protein 0.0121 0.0301 0.0298
Echinococcus granulosus TGF beta signal transducer SmadC 0.0008 0.0004 0.0001
Schistosoma mansoni hypothetical protein 0.0016 0.0023 0.002
Schistosoma mansoni hypothetical protein 0.0034 0.0071 0.0068
Echinococcus multilocularis mothers against decapentaplegic 5 0.0008 0.0004 0.0001
Schistosoma mansoni smad 0.0008 0.0004 0.0001
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0032 0.1243
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0053 0.1737
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.01 0.0097
Trypanosoma cruzi PAB1-binding protein , putative 0.0052 0.0118 0.0383
Brugia malayi brahma associated protein 60 kDa 0.0011 0.0011 0.0008
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0118 0.0293 1
Echinococcus multilocularis smad 0.0008 0.0004 0.0001
Echinococcus granulosus Upstream activation factor subunit UAF30 0.0011 0.0011 0.0008
Onchocerca volvulus 0.0239 0.0614 1
Brugia malayi MH2 domain containing protein 0.0008 0.0004 0.0001
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.0053 0.1737
Schistosoma mansoni hypothetical protein 0.0011 0.0011 0.0008
Loa Loa (eye worm) SWIB/MDM2 domain-containing protein 0.0011 0.0011 0.0008
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0027 0.0053 0.2047
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.1147 0.3013 1
Brugia malayi MH1 domain containing protein 0.0008 0.0004 0.0001
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0105 0.026 1
Echinococcus multilocularis 3'(2'),5' bisphosphate nucleotidase 1 0.0012 0.0015 0.0012
Schistosoma mansoni smad1 5 8 and 0.0008 0.0004 0.0001
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0023 0.002
Entamoeba histolytica acyl-coA synthetase, putative 0.0027 0.0053 0.1737
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0071 0.0068
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0062 0.0059
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0012
Loa Loa (eye worm) hypothetical protein 0.0016 0.0023 0.002
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.01 0.0097
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.0011 0.0011 0.0684
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0118 0.0293 1
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0023 0.002
Schistosoma mansoni survival motor neuron protein 0.0047 0.0106 0.0103
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0032 0.1243
Plasmodium vivax acyl-CoA synthetase, putative 0.002 0.0035 0.2803
Schistosoma mansoni smad1 5 8 and 0.0008 0.0004 0.0001
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.01 0.0097
Trichomonas vaginalis inositol monophosphatase, putative 0.0012 0.0015 0.019
Loa Loa (eye worm) hypothetical protein 0.0027 0.0053 0.005
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0023 0.002
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0062 0.0059
Mycobacterium ulcerans monophosphatase CysQ 0.0012 0.0015 0.0402
Schistosoma mansoni hypothetical protein 0.0012 0.0015 0.0012
Trichomonas vaginalis inositol monophosphatase, putative 0.0118 0.0293 0.4741
Loa Loa (eye worm) hypothetical protein 0.0027 0.0053 0.005
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0118 0.0293 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0032 0.1243
Echinococcus multilocularis muscleblind protein 0.0308 0.0797 0.0794
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.0011 0.0011 0.0684
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0053 0.1737
Onchocerca volvulus 0.015 0.038 0.6161
Toxoplasma gondii hypothetical protein 0.0012 0.0015 0.0402
Schistosoma mansoni hypothetical protein 0.0011 0.0011 0.0008
Leishmania major hypothetical protein, conserved 0.0052 0.0118 0.398
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0023 0.002
Onchocerca volvulus Inositol monophosphatase 3 homolog 0.0012 0.0015 0.019
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.01 0.0097
Trypanosoma cruzi inositol polyphosphate 1-phosphatase, putative 0.0012 0.0015 0.0039
Loa Loa (eye worm) hypothetical protein 0.0034 0.0071 0.0069
Echinococcus multilocularis Upstream activation factor subunit UAF30 0.0011 0.0011 0.0008
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0062 0.2027
Brugia malayi Muscleblind-like protein 0.0308 0.0797 0.0794
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0062 0.0059
Plasmodium falciparum ataxin-2 like protein, putative 0.0052 0.0118 1
Loa Loa (eye worm) transcription factor SMAD2 0.0121 0.0301 0.0298
Mycobacterium ulcerans hypothetical protein 0.0027 0.0053 0.1737
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.0011 0.0011 0.0272
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0059 0.0056
Echinococcus granulosus muscleblind protein 0.0308 0.0797 0.0794
Echinococcus multilocularis geminin 0.0193 0.0492 0.0489
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0027 0.0053 0.1737
Loa Loa (eye worm) hypothetical protein 0.002 0.0035 0.0032
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.01 0.0097
Chlamydia trachomatis 3'(2'),5'-bisphosphate nucleotidase CysQ 0.0012 0.0015 0.1533
Plasmodium vivax SWIB/MDM2 domain-containing protein, putative 0.0011 0.0011 0.0684
Trichomonas vaginalis inositol monophosphatase, putative 0.0012 0.0015 0.019
Echinococcus granulosus GPCR family 2 0.0016 0.0023 0.002
Plasmodium vivax ataxin-2 like protein, putative 0.0052 0.0118 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0027 0.0053 0.2047
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0023 0.002
Echinococcus multilocularis SWI:SNF matrix associated 0.0011 0.0011 0.0008
Brugia malayi SWIB/MDM2 domain containing protein 0.0011 0.0011 0.0008
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0008 0.0003 0.0112
Echinococcus multilocularis inositol monophosphatase 0.0012 0.0015 0.0012
Schistosoma mansoni hypothetical protein 0.0016 0.0023 0.002
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.0043 0.004
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0118 0.0293 0.4741
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0053 0.005
Schistosoma mansoni hypothetical protein 0.0016 0.0023 0.002
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0008 0.0004 0.0001
Onchocerca volvulus 0.003 0.0062 0.0961
Toxoplasma gondii LsmAD domain-containing protein 0.0052 0.0118 0.398
Brugia malayi Inositol monophosphatase family protein 0.0012 0.0015 0.0012
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.01 0.0097
Echinococcus multilocularis GPCR, family 2 0.0016 0.0023 0.002
Schistosoma mansoni hypothetical protein 0.0193 0.0492 0.0489
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0027 0.0053 0.1737
Trichomonas vaginalis diphosphonucleoside phosphohydrolase, putative 0.0012 0.0015 0.019
Plasmodium vivax hypothetical protein, conserved 0.0011 0.0011 0.0684
Mycobacterium ulcerans fatty-acid-CoA ligase 0.002 0.0035 0.1116
Loa Loa (eye worm) hypothetical protein 0.0308 0.0797 0.0795
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.0053 0.1737
Brugia malayi MH2 domain containing protein 0.0008 0.0004 0.0001
Loa Loa (eye worm) hypothetical protein 0.0027 0.0053 0.005
Trypanosoma cruzi myo-inositol-1 phosphatase, putative 0.0012 0.0015 0.0039
Giardia lamblia Hypothetical protein 0.0012 0.0015 0.5
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0008 0.0003 0.0112
Echinococcus multilocularis muscleblind protein 1 0.0308 0.0797 0.0794
Loa Loa (eye worm) hypothetical protein 0.002 0.0035 0.0032
Entamoeba histolytica 3(2),5-bisphosphate nucleotidase, putative 0.0012 0.0015 0.0402
Mycobacterium leprae POSSIBLE MONOPHOSPHATASE CYSQ 0.0012 0.0015 0.0452
Schistosoma mansoni inositol monophosphatase 0.0118 0.0293 0.029
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0062 0.0059
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0053 0.005
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0062 0.0059
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0008 0.0003 0.0112
Toxoplasma gondii SWIB/MDM2 domain-containing protein 0.0011 0.0011 0.0272
Schistosoma mansoni hypothetical protein 0.0012 0.0015 0.0012
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0027 0.0053 0.1957
Loa Loa (eye worm) hypothetical protein 0.002 0.0035 0.0032
Brugia malayi Inositol monophosphatase family protein 0.0012 0.0015 0.0012
Loa Loa (eye worm) MH2 domain-containing protein 0.0008 0.0004 0.0001
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0105 0.026 1
Loa Loa (eye worm) Smad1 0.0008 0.0004 0.0001
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0012
Trypanosoma brucei inositol-1(or 4)-monophosphatase, putative 0.0012 0.0015 0.0402
Echinococcus multilocularis SWI:SNF matrix associated 0.0011 0.0011 0.0008
Schistosoma mansoni hypothetical protein 0.0193 0.0492 0.0489
Plasmodium vivax SET domain protein, putative 0.003 0.0062 0.5092
Echinococcus granulosus SWI:SNF matrix associated 0.0011 0.0011 0.0008
Echinococcus multilocularis SWI:SNF matrix associated 0.0011 0.0011 0.0008
Echinococcus granulosus smad 0.0008 0.0004 0.0001
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0032 0.1243
Schistosoma mansoni brg-1 associated factor 0.0011 0.0011 0.0008
Loa Loa (eye worm) hypothetical protein 0.0308 0.0797 0.0795
Brugia malayi hypothetical protein 0.015 0.038 0.0377
Echinococcus multilocularis Smad4 0.0008 0.0004 0.0001
Brugia malayi hypothetical protein 0.023 0.0591 0.0588
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0008 0.0003 0.0112
Mycobacterium tuberculosis Monophosphatase CysQ 0.0012 0.0015 0.0559
Mycobacterium ulcerans monophosphatase CysQ 0.0012 0.0015 0.0402
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0062 0.0059
Loa Loa (eye worm) hypothetical protein 0.023 0.0591 0.0589
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0118 0.0293 1
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.01 0.0097
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.002 0.0035 1
Brugia malayi hypothetical protein 0.0052 0.0118 0.0115
Leishmania major myo-inositol-1 phosphatase, putative 0.0012 0.0015 0.0402
Mycobacterium tuberculosis Probable monophosphatase 0.0012 0.0015 0.0559
Brugia malayi MH2 domain containing protein 0.0121 0.0301 0.0298
Brugia malayi Pre-SET motif family protein 0.003 0.0062 0.0059
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.379 1 1
Echinococcus granulosus geminin 0.0193 0.0492 0.0489
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0062 0.0059
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0118 0.0293 1
Echinococcus granulosus inositol monophosphatase 1 0.0118 0.0293 0.029
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0118 0.0293 0.4741
Loa Loa (eye worm) hypothetical protein 0.3785 0.9985 1
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0118 0.0293 0.0963
Loa Loa (eye worm) hypothetical protein 0.003 0.0062 0.0059
Entamoeba histolytica 3(2),5-bisphosphate nucleotidase, putative 0.0012 0.0015 0.0402
Loa Loa (eye worm) MH1 domain-containing protein 0.0008 0.0004 0.0001
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0053 0.1737
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0113 0.011
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0053 0.1737
Loa Loa (eye worm) hypothetical protein 0.002 0.0035 0.0032
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0008 0.0003 0.0112
Loa Loa (eye worm) hypothetical protein 0.1141 0.2999 0.3001
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0027 0.0053 0.1737
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0008 0.0003 0.0112
Echinococcus granulosus inositol monophosphatase 0.0012 0.0015 0.0012
Trichomonas vaginalis set domain proteins, putative 0.0239 0.0614 1
Loa Loa (eye worm) STE/STE11/ASK protein kinase 0.1147 0.3013 0.3016
Schistosoma mansoni protein kinase 0.379 1 1
Schistosoma mansoni myo inositol monophosphatase 0.0012 0.0015 0.0012
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.379 1 1
Trypanosoma cruzi PAB1-binding protein , putative 0.0052 0.0118 0.0383
Brugia malayi brahma associated protein 60 kDa 0.0011 0.0011 0.0008
Loa Loa (eye worm) brahma associated protein 0.0011 0.0011 0.0008
Leishmania major inositol polyphosphate 1-phosphatase, putative 0.0012 0.0015 0.0402
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0027 0.0053 0.1737
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0053 0.1737
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0027 0.0053 0.1957
Echinococcus multilocularis inositol monophosphatase 1 0.0118 0.0293 0.029
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.01 0.0097
Schistosoma mansoni hypothetical protein 0.0047 0.0106 0.0103
Echinococcus granulosus mothers against decapentaplegic 5 0.0008 0.0004 0.0001
Schistosoma mansoni Smad4 0.0008 0.0004 0.0001
Echinococcus granulosus Smad4 0.0008 0.0004 0.0001
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.0043 0.004
Mycobacterium ulcerans monophosphatase 0.0012 0.0015 0.0402
Schistosoma mansoni hypothetical protein 0.0011 0.0011 0.0008
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0008 0.0004 0.0001
Plasmodium falciparum acyl-CoA synthetase 0.002 0.0035 0.2803
Schistosoma mansoni inositol monophosphatase 0.0118 0.0293 0.029
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0053 0.005
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.01 0.0097
Schistosoma mansoni pap-inositol-14-phosphatase 0.0012 0.0015 0.0012
Onchocerca volvulus 0.0011 0.0011 0.0129
Brugia malayi Smad1 0.0008 0.0004 0.0001
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0053 0.1737
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0008 0.0003 0.0112
Echinococcus granulosus 3'2'5' bisphosphate nucleotidase 1 0.0012 0.0015 0.0012
Loa Loa (eye worm) hypothetical protein 0.015 0.038 0.0377
Onchocerca volvulus 0.0027 0.0053 0.0824
Brugia malayi hypothetical protein 0.0033 0.007 0.0067
Trypanosoma brucei PAB1-binding protein , putative 0.0052 0.0118 0.398
Mycobacterium ulcerans inositol-monophosphatase ImpA 0.0012 0.0015 0.0402
Schistosoma mansoni protein kinase 0.379 1 1
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0008 0.0003 0.0112
Brugia malayi Inositol-1 0.0118 0.0293 0.029
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0106 0.0103
Echinococcus granulosus survival motor neuron protein 1 0.023 0.0591 0.0588
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.021 0.0538 0.0536
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0008 0.0003 0.0112
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0023 0.002
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0118 0.0293 0.0963
Brugia malayi MH1 domain containing protein 0.0008 0.0004 0.0001
Loa Loa (eye worm) hypothetical protein 0.0049 0.0113 0.011
Brugia malayi Pre-SET motif family protein 0.021 0.0538 0.0535
Onchocerca volvulus 0.0047 0.0106 0.1689
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0118 0.0293 0.5
Mycobacterium leprae Probable monophosphatase 0.0012 0.0015 0.0452
Loa Loa (eye worm) inositol-1 0.0118 0.0293 0.029
Schistosoma mansoni hypothetical protein 0.0016 0.0023 0.002
Schistosoma mansoni smad1 5 8 and 0.0008 0.0004 0.0001
Echinococcus multilocularis survival motor neuron protein 1 0.023 0.0591 0.0588
Schistosoma mansoni hypothetical protein 0.0023 0.0043 0.004
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0113 0.011
Plasmodium falciparum ataxin-2 like protein, putative 0.0052 0.0118 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0113 0.011
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0011 0.0129
Loa Loa (eye worm) hypothetical protein 0.0052 0.0118 0.0116
Loa Loa (eye worm) hypothetical protein 0.002 0.0035 0.0032
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.002 0.0035 0.1355
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0008 0.0003 0.0112
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.1147 0.3013 1
Trypanosoma brucei inositol polyphosphate 1-phosphatase, putative 0.0012 0.0015 0.0402
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0008 0.0003 0.0112
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0012 0.0015 0.019
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0023 0.002

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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