Detailed information for compound 719767

Basic information

Technical information
  • TDR Targets ID: 719767
  • Name: methyl 2-[(5-nitropyridin-2-yl)carbamoylamino ]benzoate
  • MW: 316.269 | Formula: C14H12N4O5
  • H donors: 2 H acceptors: 5 LogP: 1.98 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: COC(=O)c1ccccc1NC(=O)Nc1ccc(cn1)[N+](=O)[O-]
  • InChi: 1S/C14H12N4O5/c1-23-13(19)10-4-2-3-5-11(10)16-14(20)17-12-7-6-9(8-15-12)18(21)22/h2-8H,1H3,(H2,15,16,17,20)
  • InChiKey: XFHGHGDWUMCWBP-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • methyl 2-[(5-nitro-2-pyridyl)carbamoylamino]benzoate
  • 2-[[[(5-nitro-2-pyridyl)amino]-oxomethyl]amino]benzoic acid methyl ester
  • 2-[(5-nitro-2-pyridyl)carbamoylamino]benzoic acid methyl ester
  • ZINC05041733
  • IVK/1222571

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0014 0.0021 0.003
Brugia malayi metabotropic glutamate receptor type 2 0.0061 0.0201 0.0248
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0012 0.0013 0.0015
Echinococcus granulosus poly ADP ribose polymerase 1 0.0144 0.0521 0.0642
Trichomonas vaginalis DNA polymerase eta, putative 0.002 0.0043 0.0053
Loa Loa (eye worm) hypothetical protein 0.01 0.0353 0.0639
Echinococcus granulosus serotonin receptor 0.0032 0.0091 0.0112
Onchocerca volvulus 0.0016 0.0031 0.0259
Brugia malayi Pre-SET motif family protein 0.003 0.0083 0.0102
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0073 0.025 0.025
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0008 0.001
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0014 0.0021 0.0026
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0012 0.0013 0.0015
Echinococcus multilocularis cysteine protease 0.0016 0.0031 0.0038
Loa Loa (eye worm) hypothetical protein 0.0032 0.0091 0.0158
Loa Loa (eye worm) hypothetical protein 0.0032 0.0091 0.0158
Loa Loa (eye worm) hypothetical protein 0.0079 0.0271 0.0489
Echinococcus granulosus cathepsin l cysteine peptidase 0.0016 0.0031 0.0038
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0036 0.0105 0.0103
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0031 0.0038
Loa Loa (eye worm) hypothetical protein 0.0036 0.0105 0.0183
Loa Loa (eye worm) hypothetical protein 0.0032 0.0091 0.0158
Leishmania major 4-coumarate:coa ligase-like protein 0.0048 0.0151 0.0139
Trichomonas vaginalis antibiotic synthetase, putative 0.0014 0.0021 0.0026
Mycobacterium ulcerans acyl-CoA synthetase 0.0048 0.0151 0.0161
Echinococcus granulosus poly (ADP ribose) polymerase 0.0022 0.0053 0.0066
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0208 0.0208
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0032 0.009 0.0112
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0073 0.025 0.0308
Echinococcus multilocularis nmda type glutamate receptor 0.0012 0.0013 0.0015
Loa Loa (eye worm) hypothetical protein 0.0032 0.0091 0.0158
Onchocerca volvulus 0.0032 0.0091 0.0966
Loa Loa (eye worm) poly(ADP-ribose) polymerase 0.0057 0.0186 0.0331
Brugia malayi Cathepsin L-like precursor 0.0016 0.0031 0.0038
Echinococcus multilocularis poly (ADP ribose) polymerase 1 0.0144 0.0521 0.0642
Brugia malayi RNA recognition motif domain containing protein 0.0064 0.0216 0.0266
Leishmania major acetyl-CoA synthetase, putative 0.0014 0.0021 0.0009
Trypanosoma brucei unspecified product 0.0014 0.002 0.002
Giardia lamblia Glyceraldehyde 3-phosphate dehydrogenase 0.1456 0.5582 0.6866
Entamoeba histolytica poly(ADP-ribose) polymerase, putative 0.0144 0.0521 0.0642
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0048 0.0151 0.0554
Loa Loa (eye worm) hypothetical protein 0.0032 0.0091 0.0158
Loa Loa (eye worm) hypothetical protein 0.0032 0.0091 0.0158
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0073 0.025 0.0308
Loa Loa (eye worm) hypothetical protein 0.0032 0.0091 0.0158
Schistosoma mansoni hypothetical protein 0.0166 0.0607 0.0749
Schistosoma mansoni poly [ADP-ribose] polymerase 0.0144 0.0521 0.0642
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.2112 0.811 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.0091 0.0112
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.2112 0.811 0.811
Echinococcus granulosus neuropeptides capa receptor 0.0032 0.0091 0.0112
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0012 0.0013 0.0015
Echinococcus granulosus geminin 0.0166 0.0607 0.0749
Echinococcus granulosus G protein coupled receptor 139 0.0032 0.0091 0.0112
Schistosoma mansoni neuropeptide F-like receptor 0.0032 0.0091 0.0112
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0031 0.0038
Echinococcus multilocularis neuropeptide Y receptor 0.0032 0.0091 0.0112
Echinococcus granulosus cathepsin l1 0.0011 0.001 0.0012
Brugia malayi G protein-coupled receptor 0.0032 0.0091 0.0112
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.0091 0.0112
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0208 0.0208
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0083 0.0102
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0208 0.0208
Schistosoma mansoni hypothetical protein 0.0032 0.009 0.0112
Loa Loa (eye worm) hypothetical protein 0.0032 0.0091 0.0158
Schistosoma mansoni microtubule-associated protein tau 0.0676 0.2574 0.3174
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative 0.0689 0.2624 0.2624
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0216 0.0266
Entamoeba histolytica deoxycytidyl transferase, putative 0.002 0.0043 0.0053
Brugia malayi Latrophilin receptor protein 2 0.0032 0.009 0.0112
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0208 0.0208
Loa Loa (eye worm) hypothetical protein 0.003 0.0083 0.0142
Loa Loa (eye worm) hypothetical protein 0.0011 0.001 0.0008
Schistosoma mansoni biogenic amine receptor 0.0032 0.0091 0.0112
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.2112 0.811 0.811
Brugia malayi TAR-binding protein 0.0064 0.0216 0.0266
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0031 0.0038
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0011 0.001 0.0012
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0083 0.0102
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0016 0.0031 0.0038
Brugia malayi Receptor family ligand binding region containing protein 0.0012 0.0013 0.0015
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0063 0.0077
Loa Loa (eye worm) hypothetical protein 0.0014 0.0021 0.003
Loa Loa (eye worm) G-protein coupled receptor 0.0032 0.0091 0.0158
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0149 0.0543 0.0644
Brugia malayi G-protein coupled receptor 0.0032 0.0091 0.0112
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.2112 0.811 1
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0014 0.0021 0.0026
Schistosoma mansoni biogenic amine (5HT) receptor 0.0032 0.0091 0.0112
Schistosoma mansoni myosin xvIII 0.0032 0.0091 0.0112
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0031 0.0038
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0032 0.0091 0.0112
Onchocerca volvulus 0.0014 0.0021 0.0152
Loa Loa (eye worm) hypothetical protein 0.0036 0.0105 0.0183
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0032 0.0091 0.0112
Brugia malayi Melatonin receptor type 1A 0.0032 0.0091 0.0112
Echinococcus granulosus dna polymerase kappa 0.002 0.0043 0.0053
Schistosoma mansoni tyrosine kinase 0.0012 0.0013 0.0015
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0043 0.0043
Echinococcus multilocularis serotonin receptor 0.0032 0.0091 0.0112
Schistosoma mansoni cpg binding protein 0.003 0.0082 0.0101
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0032 0.0091 0.0112
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0032 0.009 0.0157
Loa Loa (eye worm) G-protein coupled receptor 0.0032 0.0091 0.0158
Leishmania major DNA repair protein, putative 0.0019 0.004 0.0027
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0057 0.0187 0.0187
Toxoplasma gondii glyceraldehyde-3-phosphate dehydrogenase GAPDH1 0.2112 0.811 1
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0016 0.0031 0.0047
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0043 0.0043
Brugia malayi WGR domain containing protein 0.0079 0.0271 0.0335
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.2112 0.811 1
Echinococcus granulosus biogenic amine 5HT receptor 0.0032 0.0091 0.0112
Onchocerca volvulus 0.0032 0.0091 0.0966
Schistosoma mansoni hypothetical protein 0.0401 0.1512 0.1865
Loa Loa (eye worm) hypothetical protein 0.0032 0.009 0.0157
Loa Loa (eye worm) hypothetical protein 0.0101 0.0356 0.0645
Loa Loa (eye worm) hypothetical protein 0.0032 0.0091 0.0158
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0032 0.009 0.0112
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0689 0.2624 0.2624
Echinococcus multilocularis orexin receptor type 2 0.0032 0.0091 0.0112
Onchocerca volvulus 0.0016 0.0031 0.0259
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0032 0.0091 0.0966
Loa Loa (eye worm) RGC/RGC protein kinase 0.0012 0.0013 0.0014
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0032 0.0091 0.0158
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0073 0.025 0.025
Loa Loa (eye worm) hypothetical protein 0.0032 0.0091 0.0158
Brugia malayi glyceraldehyde 3-phosphate dehydrogenase 0.0689 0.2624 0.3236
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0031 0.0038
Onchocerca volvulus 0.0032 0.0091 0.0966
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0014 0.0021 0.003
Echinococcus multilocularis g-protein coupled receptor 0.0032 0.0091 0.0112
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0031 0.0038
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.2112 0.811 1
Onchocerca volvulus 0.0032 0.0091 0.0966
Schistosoma mansoni adenoreceptor 0.0032 0.0091 0.0112
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0043 0.0133 0.0235
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, cytosolic 0.2112 0.811 0.811
Brugia malayi RE15519p 0.0032 0.0091 0.0112
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.2112 0.811 1
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0043 0.0043
Brugia malayi F/Y-rich N-terminus family protein 0.001 0.0005 0.0006
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0073 0.025 0.0308
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0014 0.0021 0.0021
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0147 0.0181
Echinococcus multilocularis neuropeptide FF receptor 2 0.0032 0.0091 0.0112
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0208 0.0208
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0142 0.0513 0.0633
Schistosoma mansoni opsin-like receptor 0.0032 0.0091 0.0112
Onchocerca volvulus 0.0032 0.0091 0.0966
Entamoeba histolytica hypothetical protein 0.0011 0.0008 0.001
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0014 0.0021 0.003
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0216 0.0266
Echinococcus granulosus Protein patched homolog 1 0.0043 0.0133 0.0164
Onchocerca volvulus Poor gastrulation protein homolog 0.002 0.0045 0.0431
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0048 0.0151 0.0161
Schistosoma mansoni amine GPCR 0.0032 0.0091 0.0112
Loa Loa (eye worm) hypothetical protein 0.0032 0.0091 0.0158
Onchocerca volvulus Metabotropic glutamate receptor homolog 0.002 0.0045 0.0431
Onchocerca volvulus 0.0032 0.0091 0.0966
Onchocerca volvulus 0.0014 0.0021 0.0152
Echinococcus granulosus neuropeptide s receptor 0.0032 0.0091 0.0112
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0012 0.0013 0.0015
Echinococcus multilocularis cysteine protease 0.0016 0.0031 0.0038
Echinococcus multilocularis neuropeptides capa receptor 0.0032 0.0091 0.0112
Brugia malayi hypothetical protein 0.0012 0.0013 0.0015
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0012 0.0013 0.0015
Loa Loa (eye worm) hypothetical protein 0.1345 0.5153 0.9448
Echinococcus multilocularis glutamate receptor 2 0.0012 0.0013 0.0015
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0043 0.0043
Wolbachia endosymbiont of Brugia malayi glyceraldehyde-3-phosphate dehydrogenase, GapA 0.2112 0.811 0.5
Echinococcus granulosus neuropeptide receptor A26 0.0032 0.0091 0.0112
Schistosoma mansoni biogenic amine receptor 0.0032 0.0091 0.0112
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.0091 0.0112
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0016 0.0031 0.0038
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0016 0.0031 0.0038
Brugia malayi RNA binding protein 0.0064 0.0216 0.0266
Schistosoma mansoni cpg binding protein 0.003 0.0082 0.0101
Echinococcus granulosus neuropeptide Y receptor 0.0032 0.0091 0.0112
Onchocerca volvulus Cathepsin L homolog 0.0016 0.0031 0.0259
Echinococcus granulosus dro:myosuppressin receptor 0.0032 0.0091 0.0112
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.2112 0.811 1
Brugia malayi Pre-SET motif family protein 0.0204 0.0756 0.0932
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0014 0.0021 0.0021
Brugia malayi Cathepsin L-like precursor 0.0016 0.0031 0.0038
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.2112 0.811 0.811
Onchocerca volvulus 0.0028 0.0076 0.0788
Schistosoma mansoni hypothetical protein 0.0032 0.0091 0.0112
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0014
Echinococcus granulosus tachykinin peptides receptor 99D 0.0032 0.0091 0.0112
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0147 0.0181
Onchocerca volvulus 0.0014 0.0021 0.0152
Echinococcus granulosus receptor type guanylyl cyclase 0.0012 0.0013 0.0015
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0031 0.0038
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0021 0.003
Loa Loa (eye worm) neuropeptide F receptor 0.0032 0.0091 0.0158
Echinococcus granulosus biogenic amine 5HT receptor 0.0032 0.0091 0.0112
Loa Loa (eye worm) hypothetical protein 0.0019 0.004 0.0063
Echinococcus multilocularis dro:myosuppressin receptor 0.0032 0.0091 0.0112
Echinococcus multilocularis g protein coupled receptor 0.0032 0.0091 0.0112
Echinococcus multilocularis ubiquitin specific protease 41 0.0073 0.025 0.0308
Echinococcus granulosus Niemann Pick C1 protein 0.01 0.0353 0.0436
Loa Loa (eye worm) hypothetical protein 0.002 0.0043 0.007
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0021 0.003
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.2112 0.811 1
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0032 0.0091 0.0112
Schistosoma mansoni neuropeptide receptor 0.0032 0.0091 0.0112
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0012 0.0013 0.0015
Loa Loa (eye worm) hypothetical protein 0.0032 0.0091 0.0158
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.1345 0.5153 0.6353
Echinococcus multilocularis poly (adp ribose) polymerase 2 0.0079 0.0271 0.0335
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.2112 0.811 1
Echinococcus granulosus tankyrase 0.0011 0.0008 0.001
Echinococcus multilocularis serotonin receptor 0.0032 0.0091 0.0112
Loa Loa (eye worm) hypothetical protein 0.0032 0.0091 0.0158
Onchocerca volvulus 0.003 0.0083 0.0865
Loa Loa (eye worm) hypothetical protein 0.0032 0.0091 0.0158
Echinococcus granulosus cathepsin l1 0.0016 0.0031 0.0038
Brugia malayi hypothetical protein 0.0032 0.0091 0.0112
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.2112 0.811 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.0105 0.0183
Echinococcus multilocularis protein dispatched 1 0.0049 0.0156 0.0193
Loa Loa (eye worm) latrophilin receptor protein 2 0.0032 0.009 0.0157
Loa Loa (eye worm) hypothetical protein 0.0043 0.0133 0.0235
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0014
Entamoeba histolytica cysteine proteinase, putative 0.0011 0.001 0.0012
Brugia malayi Cathepsin L-like precursor 0.0016 0.0031 0.0038
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0031 0.0038
Brugia malayi neuropeptide F receptor 0.0032 0.0091 0.0112
Brugia malayi G-protein coupled receptor 0.0032 0.0091 0.0112
Schistosoma mansoni biogenic amine (5HT) receptor 0.0032 0.0091 0.0112
Schistosoma mansoni hypothetical protein 0.0166 0.0607 0.0749
Onchocerca volvulus Cathepsin F homolog 0.0016 0.0031 0.0259
Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase, putative 0.2602 1 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0031 0.0038
Loa Loa (eye worm) glyceraldehyde 3-phosphate dehydrogenase 0.1345 0.5153 0.9448
Echinococcus multilocularis neuropeptide receptor 0.0032 0.0091 0.0112
Loa Loa (eye worm) hypothetical protein 0.0032 0.0091 0.0158
Loa Loa (eye worm) hypothetical protein 0.0032 0.0091 0.0158
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0043 0.0117
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0083 0.0102
Brugia malayi Cathepsin L-like precursor 0.0011 0.001 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0008 0.001
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0043 0.0053
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0032 0.0091 0.0112
Mycobacterium tuberculosis Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH) 0.0656 0.2496 1
Echinococcus multilocularis cathepsin L cysteine protease 0.0016 0.0031 0.0038
Echinococcus multilocularis neuropeptide receptor 0.0032 0.0091 0.0112
Leishmania major cathepsin L-like protease 0.0016 0.0031 0.0018
Brugia malayi Dopamine receptor protein 2 0.0032 0.0091 0.0112
Schistosoma mansoni growth hormone secretagogue receptor 0.0032 0.0091 0.0112
Schistosoma mansoni patched 1 0.0043 0.0133 0.0164
Onchocerca volvulus 0.0016 0.0031 0.0259
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0032 0.0091 0.0112
Loa Loa (eye worm) melatonin receptor type 1A 0.0032 0.0091 0.0158
Loa Loa (eye worm) glyceraldehyde-3-phosphate dehydrogenase 0.1423 0.5453 1
Leishmania major DNA polymerase kappa, putative 0.002 0.0043 0.0031
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.2112 0.811 1
Onchocerca volvulus 0.0032 0.0091 0.0966
Trypanosoma cruzi poly(ADP-ribose) polymerase, putative 0.0079 0.0271 0.0271
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0113 0.0402 0.0496
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0012 0.0013 0.0015
Loa Loa (eye worm) glutamate receptor 0.0125 0.0447 0.0812
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0073 0.025 0.0308
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.0091 0.0112
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0012 0.0013 0.0014
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0032 0.0091 0.0112
Brugia malayi Cathepsin L-like precursor 0.0016 0.0031 0.0038
Brugia malayi hypothetical protein 0.0032 0.0091 0.0112
Loa Loa (eye worm) oxidoreductase 0.0014 0.0021 0.003
Echinococcus granulosus somatostatin receptor 0.0032 0.0091 0.0112
Echinococcus multilocularis neuropeptide s receptor 0.0032 0.0091 0.0112
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.0091 0.0112
Brugia malayi Receptor family ligand binding region containing protein 0.0032 0.009 0.0112
Brugia malayi Tnks protein 0.0011 0.0008 0.001
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0048 0.0151 0.0269
Brugia malayi metabotropic GABA-B receptor subtype 2 0.002 0.0045 0.0056
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0008 0.001
Echinococcus granulosus g protein coupled receptor 0.0032 0.0091 0.0112
Echinococcus granulosus sterol regulatory element binding protein 0.0043 0.0133 0.0164
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0083 0.0102
Echinococcus multilocularis cpg binding protein 0.003 0.0082 0.0101
Echinococcus granulosus poly (ADP ribose) polymerase 0.0022 0.0053 0.0066
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0014 0.0021 0.0021
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0014 0.0021 0.0021
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0032 0.0091 0.0112
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0063 0.0063
Echinococcus granulosus poly (ADP ribose) polymerase 0.0022 0.0053 0.0066
Plasmodium vivax SET domain protein, putative 0.003 0.0083 0.0102
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0031 0.0038
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.0091 0.0112
Loa Loa (eye worm) hypothetical protein 0.0032 0.0091 0.0158
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0008 0.001
Trypanosoma cruzi cysteine peptidase, putative 0.0016 0.0031 0.0031
Leishmania major cathepsin L-like protease 0.0016 0.0031 0.0018
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.2112 0.811 1
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0063 0.0051
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0014 0.0021 0.003
Echinococcus granulosus orexin receptor type 2 0.0032 0.0091 0.0112
Brugia malayi cathepsin L-like precursor 0.0011 0.001 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0133 0.0164
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0014
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.2112 0.811 1
Loa Loa (eye worm) hypothetical protein 0.0048 0.0151 0.0269
Schistosoma mansoni biogenic amine receptor 0.0032 0.0091 0.0112
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0097 0.0336
Loa Loa (eye worm) hypothetical protein 0.0032 0.0091 0.0158
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0021 0.003
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0043 0.0043
Echinococcus granulosus poly (ADP ribose) polymerase 0.0045 0.0139 0.0172
Echinococcus granulosus ubiquitin specific protease 41 0.0073 0.025 0.0308
Toxoplasma gondii cathepsin CPL 0.0016 0.0031 0.0011
Brugia malayi neuropeptide F receptor 0.0032 0.0091 0.0112
Entamoeba histolytica hypothetical protein 0.0011 0.0008 0.001
Loa Loa (eye worm) hypothetical protein 0.0032 0.0091 0.0158
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0011 0.001 0.0012
Brugia malayi Serotonin receptor 0.0032 0.0091 0.0112
Schistosoma mansoni hypothetical protein 0.0041 0.0127 0.0157
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0014 0.0021 0.0021
Echinococcus multilocularis neuropeptide Y receptor 0.0032 0.0091 0.0112
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0216 0.0266
Schistosoma mansoni histamine h1 receptor 0.0032 0.0091 0.0112
Treponema pallidum glyceraldehyde 3-phosphate dehydrogenase (gap) 0.2112 0.811 0.5
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.002 0.0043 0.0053
Echinococcus granulosus poly adp ribose polymerase 2 0.0079 0.0271 0.0335
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0008 0.001
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.0091 0.0112
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.0091 0.0112
Onchocerca volvulus 0.0016 0.0031 0.0259
Entamoeba histolytica hypothetical protein 0.0022 0.0053 0.0066
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.1345 0.5153 0.6353
Echinococcus multilocularis somatostatin receptor 0.0032 0.0091 0.0112
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0048 0.0151 0.0161
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0031 0.0038
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.0091 0.0112
Schistosoma mansoni glutamate receptor NMDA 0.0012 0.0013 0.0015
Echinococcus multilocularis geminin 0.0166 0.0607 0.0749
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0032 0.0091 0.0112
Schistosoma mansoni hypothetical protein 0.002 0.0045 0.0056
Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase, putative 0.2602 1 1
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0012 0.0013 0.0048
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0032 0.0091 0.0112
Echinococcus multilocularis fmrfamide receptor 0.0032 0.0091 0.0112
Schistosoma mansoni hypothetical protein 0.0069 0.0233 0.0288
Brugia malayi AKH receptor 0.0032 0.0091 0.0112
Echinococcus multilocularis expressed conserved protein 0.0094 0.033 0.0407
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.2112 0.811 0.811
Echinococcus multilocularis G-protein coupled receptor, putative 0.0032 0.0091 0.0112
Brugia malayi AMP-binding enzyme family protein 0.0048 0.0151 0.0187
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.0091 0.0112
Echinococcus granulosus atrial natriuretic peptide receptor 0.0012 0.0013 0.0015
Echinococcus granulosus neuropeptide receptor 0.0032 0.0091 0.0112
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.2112 0.811 0.811
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0147 0.0181
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0036 0.0105 0.0367
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0043 0.0043
Schistosoma mansoni cathepsin F (C01 family) 0.0016 0.0031 0.0038
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0073 0.025 0.0308
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0208 0.0208
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0043 0.0043
Echinococcus granulosus metabotropic glutamate receptor 5 0.0153 0.0558 0.0689
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.2112 0.811 1
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.2112 0.811 0.811
Echinococcus multilocularis Niemann Pick C1 protein 0.0143 0.0519 0.064
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0104 0.037 0.0456
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0031 0.0038
Brugia malayi hypothetical protein 0.0032 0.0091 0.0112
Schistosoma mansoni protein kinase 0.0012 0.0013 0.0015
Echinococcus granulosus peptide allatostatin:somatostatin 0.0032 0.0091 0.0112
Plasmodium vivax vivapain-2 0.0016 0.0031 0.0038
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0147 0.0181
Echinococcus granulosus microtubule associated protein 2 0.0676 0.2574 0.3174
Loa Loa (eye worm) RGC/RGC protein kinase 0.0012 0.0013 0.0014
Echinococcus multilocularis allatostatin A receptor 0.0032 0.0091 0.0112
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0208 0.0208
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0204 0.0756 0.1378
Loa Loa (eye worm) hypothetical protein 0.0011 0.001 0.0008
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.2112 0.811 1
Trypanosoma cruzi major cysteine proteinase, putative 0.0049 0.0157 0.0157
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0083 0.0076
Schistosoma mansoni poly [ADP-ribose] polymerase 0.0079 0.0271 0.0335
Schistosoma mansoni neuropeptide receptor 0.0032 0.0091 0.0112
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0032 0.0091 0.0112
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0097 0.0336
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0208 0.0208
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0032 0.0091 0.0112
Schistosoma mansoni amine GPCR 0.0032 0.0091 0.0112
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.0091 0.0112
Echinococcus multilocularis G protein coupled receptor 139 0.0032 0.0091 0.0112
Brugia malayi hypothetical protein 0.0032 0.0091 0.0112
Onchocerca volvulus 0.0032 0.0091 0.0966
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0043 0.0027
Brugia malayi AMP-binding enzyme family protein 0.0048 0.0151 0.0187
Schistosoma mansoni hypothetical protein 0.0032 0.009 0.0112
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0208 0.0208
Entamoeba histolytica acyl-CoA synthetase, putative 0.0048 0.0151 0.0187
Loa Loa (eye worm) hypothetical protein 0.0032 0.0091 0.0158
Onchocerca volvulus 0.0032 0.0091 0.0966
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0097 0.0336
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0012 0.0013 0.0015
Onchocerca volvulus 0.0032 0.0091 0.0966
Echinococcus multilocularis g protein coupled receptor 0.0032 0.0091 0.0112
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0032 0.009 0.0112
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0043 0.0043
Plasmodium falciparum cysteine proteinase falcipain 3 0.0016 0.0031 0.0038
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0032 0.0091 0.0158
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0005 0.0006
Brugia malayi Guanylyl cyclase protein 23 0.0012 0.0013 0.0015
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0032 0.0091 0.0112
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.1345 0.5153 0.6353
Echinococcus granulosus 7tm_1 domain containing protein 0.0032 0.0091 0.0112
Loa Loa (eye worm) hypothetical protein 0.0032 0.0091 0.0158
Echinococcus granulosus dna polymerase eta 0.002 0.0043 0.0053
Loa Loa (eye worm) hypothetical protein 0.0032 0.0091 0.0158
Echinococcus granulosus alpha 1A adrenergic receptor 0.0032 0.0091 0.0112
Plasmodium vivax acyl-CoA synthetase, putative 0.0036 0.0105 0.0129
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0032 0.0091 0.0112
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.0091 0.0112
Loa Loa (eye worm) hypothetical protein 0.0032 0.0091 0.0158
Brugia malayi WGR domain containing protein 0.0144 0.0521 0.0642
Schistosoma mansoni hypothetical protein 0.0032 0.0091 0.0112
Brugia malayi GnHR receptor homolog 0.0032 0.0091 0.0112
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0014 0.0021 0.003
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0073 0.025 0.0257
Schistosoma mansoni hypothetical protein 0.0041 0.0127 0.0157
Chlamydia trachomatis glyceraldehyde-3-phosphate dehydrogenase 0.2112 0.811 1
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0043 0.0043
Brugia malayi Niemann-Pick C1 protein precursor 0.01 0.0353 0.0436
Loa Loa (eye worm) tnks protein 0.0011 0.0008 0.0006
Loa Loa (eye worm) hypothetical protein 0.0073 0.025 0.045
Leishmania major glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.2112 0.811 0.8108
Brugia malayi Glyceraldehyde 3-phosphate dehydrogenase 0.0767 0.2925 0.3607
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0073 0.025 0.0308
Schistosoma mansoni hypothetical protein 0.0032 0.009 0.0112
Echinococcus multilocularis receptor type guanylyl cyclase 0.0012 0.0013 0.0015
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0031 0.0038
Loa Loa (eye worm) hypothetical protein 0.0032 0.0091 0.0158
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0032 0.0091 0.0112
Brugia malayi hypothetical protein 0.0016 0.0029 0.0036
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0153 0.0558 0.0689
Leishmania major cathepsin L-like protease 0.0016 0.0031 0.0018
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0031 0.0038
Brugia malayi Glyceraldehyde 3-phosphate dehydrogenase 0.2112 0.811 1
Loa Loa (eye worm) hypothetical protein 0.0011 0.001 0.0008
Entamoeba histolytica zinc finger protein, putative 0.0011 0.0008 0.001
Leishmania major cathepsin L-like protease 0.0062 0.0208 0.0196
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0063 0.0077
Echinococcus multilocularis GPCR, family 2 0.0032 0.009 0.0112
Brugia malayi sulfakinin receptor protein 0.0032 0.0091 0.0112
Schistosoma mansoni DNA polymerase eta 0.002 0.0043 0.0053
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0208 0.0208
Trypanosoma cruzi DNA repair protein, putative 0.0019 0.004 0.004
Loa Loa (eye worm) neuropeptide F receptor 0.0032 0.0091 0.0158
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.002 0.002
Onchocerca volvulus 0.0032 0.0091 0.0966
Schistosoma mansoni cathepsin F (C01 family) 0.0011 0.001 0.0012
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0073 0.025 0.025
Leishmania major cathepsin L-like protease 0.0016 0.0031 0.0018
Echinococcus granulosus cathepsin L cysteine proteinase 0.0016 0.0031 0.0038
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0032 0.0091 0.0112
Onchocerca volvulus 0.0048 0.0151 0.167
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0101 0.0356 0.0645
Brugia malayi Calcitonin receptor-like protein seb-1 0.0101 0.0356 0.0439
Brugia malayi ORL1-like opioid receptor 0.0032 0.0091 0.0112
Onchocerca volvulus 0.0016 0.0031 0.0259
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0014 0.0021 0.003
Loa Loa (eye worm) hypothetical protein 0.0032 0.0091 0.0158
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0031 0.0038
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0031 0.0038
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0014 0.0021 0.0009
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0032 0.0091 0.0158
Echinococcus multilocularis neuropeptide receptor A26 0.0032 0.0091 0.0112
Brugia malayi Dopamine receptor protein 1 0.0032 0.0091 0.0112
Loa Loa (eye worm) fibroinase 0.0016 0.0031 0.0047
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0032 0.0091 0.0112
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0012 0.0013 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0008 0.001
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0016 0.0031 0.0038
Echinococcus granulosus GPCR family 3 C terminal 0.002 0.0045 0.0056
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0032 0.0091 0.0112
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0097 0.0336
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0147 0.0181
Onchocerca volvulus 0.0032 0.0091 0.0966
Loa Loa (eye worm) hypothetical protein 0.0032 0.0091 0.0158
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0073 0.025 0.0308
Brugia malayi hypothetical protein 0.0032 0.0091 0.0112
Echinococcus granulosus tm gpcr rhodopsin 0.0032 0.0091 0.0112
Loa Loa (eye worm) glutamate receptor 0.0049 0.0156 0.0277
Loa Loa (eye worm) hypothetical protein 0.0032 0.0091 0.0158
Echinococcus multilocularis dna polymerase eta 0.002 0.0043 0.0053
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0032 0.0091 0.0112
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0043 0.0043
Trypanosoma brucei DNA polymerase eta, putative 0.002 0.0043 0.0043
Entamoeba histolytica acyl-CoA synthetase, putative 0.0048 0.0151 0.0187
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0208 0.0208
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0014 0.0021 0.003
Onchocerca volvulus 0.0012 0.0013 0.0048
Leishmania major cathepsin L-like protease 0.0062 0.0208 0.0196
Echinococcus granulosus 7TM GPCR rhodopsin 0.0032 0.0091 0.0112
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0014 0.0021 0.0026
Mycobacterium ulcerans glyceraldehyde 3-phosphate dehydrogenase Gap 0.2112 0.811 1
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0032 0.0091 0.0112
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.002 0.0043 0.0053
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0014 0.0021 0.003
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0063 0.0063
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0032 0.0091 0.0112
Onchocerca volvulus 0.0011 0.001 0.0015
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.0091 0.0112
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.2112 0.811 1
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0008 0.001
Loa Loa (eye worm) hypothetical protein 0.0032 0.0091 0.0158
Brugia malayi Tachykinin-like peptides receptor 99D 0.0032 0.0091 0.0112
Entamoeba histolytica cysteine proteinase, putative 0.0016 0.0031 0.0038
Echinococcus granulosus neuropeptide Y receptor 0.0032 0.0091 0.0112
Loa Loa (eye worm) hypothetical protein 0.0032 0.0091 0.0158
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0208 0.0208
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.002 0.002
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0048 0.0151 0.0554
Echinococcus multilocularis tar DNA binding protein 0.0064 0.0216 0.0266
Echinococcus multilocularis dna polymerase kappa 0.002 0.0043 0.0053
Echinococcus granulosus sex peptide receptor 0.0032 0.0091 0.0112
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0047 0.0147 0.026
Trypanosoma cruzi poly(ADP-ribose) polymerase, putative 0.0079 0.0271 0.0271
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0147 0.0181
Trypanosoma brucei DNA repair protein, putative 0.0019 0.004 0.004
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0032 0.0091 0.0112
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0043 0.0043
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0043 0.0043
Giardia lamblia Glyceraldehyde 3-phosphate dehydrogenase 0.2112 0.811 1
Leishmania major cathepsin L-like protease 0.0016 0.0031 0.0018
Echinococcus granulosus hypothetical protein 0.0032 0.0091 0.0112
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0014 0.0021 0.0026
Echinococcus granulosus neuropeptide FF receptor 2 0.0032 0.0091 0.0112
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0008 0.001
Trypanosoma cruzi cruzipain precursor, putative 0.0062 0.0208 0.0208
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0031 0.0038
Brugia malayi hypothetical protein 0.0032 0.0091 0.0112
Leishmania major DNA polymerase eta, putative 0.002 0.0043 0.0031
Onchocerca volvulus 0.0032 0.0091 0.0966
Schistosoma mansoni neuropeptide f receptor 76f 0.0032 0.0091 0.0112
Schistosoma mansoni acetyl-CoA synthetase 0.0014 0.0021 0.0026
Loa Loa (eye worm) hypothetical protein 0.0032 0.0091 0.0158
Echinococcus multilocularis sterol regulatory element binding protein 0.0043 0.0133 0.0164
Loa Loa (eye worm) hypothetical protein 0.0032 0.0091 0.0158
Brugia malayi Serotonin receptor 0.0032 0.0091 0.0112
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0014
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0043 0.0043
Echinococcus multilocularis GPCR, family 3, C terminal 0.002 0.0045 0.0056
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.2112 0.811 0.811
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0014 0.0021 0.003
Echinococcus granulosus GPCR family 2 0.0032 0.009 0.0112
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0032 0.0091 0.0112
Trichomonas vaginalis conserved hypothetical protein 0.0073 0.025 0.0308
Brugia malayi G protein-coupled receptor F59B2.13 0.0032 0.0091 0.0112
Schistosoma mansoni hypothetical protein 0.0011 0.001 0.0012
Schistosoma mansoni amine GPCR 0.0032 0.0091 0.0112
Brugia malayi CXXC zinc finger family protein 0.0028 0.0076 0.0094
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0032 0.0091 0.0112
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0005 0.0006
Brugia malayi Cathepsin L-like precursor 0.0011 0.001 0.0012
Echinococcus granulosus tar DNA binding protein 0.0064 0.0216 0.0266
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0043 0.0053
Onchocerca volvulus 0.0014 0.0021 0.0152
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0032 0.0091 0.0112
Onchocerca volvulus Cathepsin L homolog 0.0016 0.0031 0.0259
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0032 0.0091 0.0112
Echinococcus granulosus WGR domain containing protein 0.0045 0.0139 0.0172
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0031 0.0038
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0032 0.009 0.0157
Echinococcus multilocularis dnaJ subfamily B 0.0401 0.1512 0.1865
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.0091 0.0112
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0031 0.0038
Brugia malayi putative neuropeptide receptor 0.0032 0.0091 0.0112
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0689 0.2624 0.2624
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0032 0.0091 0.0158
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0064 0.0216 0.0387
Echinococcus granulosus nmda type glutamate receptor 0.0012 0.0013 0.0015
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0216 0.0266
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0083 0.0102
Loa Loa (eye worm) glyceraldehyde-3-phosphate dehydrogenase 0.1423 0.5453 1
Brugia malayi hypothetical protein 0.0032 0.0091 0.0112
Loa Loa (eye worm) hypothetical protein 0.0032 0.0091 0.0158
Brugia malayi hypothetical protein 0.0032 0.0091 0.0112
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.002 0.0043 0.0117
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0216 0.0266
Onchocerca volvulus 0.0032 0.0091 0.0966
Echinococcus granulosus dnaJ subfamily B 0.0401 0.1512 0.1865
Echinococcus granulosus glutamate receptor 2 0.0012 0.0013 0.0015
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0014
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.2112 0.811 1
Loa Loa (eye worm) TYRA-2 protein 0.0032 0.0091 0.0158
Loa Loa (eye worm) hypothetical protein 0.0032 0.0091 0.0158
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0021 0.0026
Leishmania major cathepsin L-like protease 0.0062 0.0208 0.0196
Echinococcus granulosus g protein coupled receptor 0.0032 0.0091 0.0112
Entamoeba histolytica hypothetical protein 0.0012 0.0013 0.0015
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0032 0.0091 0.0112
Loa Loa (eye worm) hypothetical protein 0.0153 0.0558 0.1016
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0021 0.0026
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0031 0.0038
Echinococcus multilocularis microtubule associated protein 2 0.0676 0.2574 0.3174
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0208 0.0208
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0014 0.0021 0.0026
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0016 0.0031 0.0038
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0016 0.0031 0.0047
Schistosoma mansoni terminal deoxycytidyl transferase 0.002 0.0043 0.0053
Echinococcus multilocularis neuropeptides capa receptor 0.0032 0.0091 0.0112
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0021 0.0026
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0073 0.025 0.0308
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0083 0.0102
Onchocerca volvulus 0.0032 0.0091 0.0966
Loa Loa (eye worm) ctsf protein 0.0016 0.0031 0.0047
Schistosoma mansoni poly [ADP-ribose] polymerase 0.0068 0.023 0.0284
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0032 0.0091 0.0112
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0032 0.0091 0.0112
Entamoeba histolytica hypothetical protein 0.0011 0.0008 0.001
Echinococcus multilocularis Niemann Pick C1 protein 0.01 0.0353 0.0436
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0021 0.003
Leishmania major hypothetical protein, conserved 0.0019 0.004 0.0027
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0021 0.0026
Trypanosoma brucei poly(adp-ribose) polymerase 0.0079 0.0271 0.0271
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0048 0.0151 0.0525
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0689 0.2624 0.2624
Loa Loa (eye worm) hypothetical protein 0.0016 0.0031 0.0047
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0767 0.2925 0.3607
Loa Loa (eye worm) hypothetical protein 0.0032 0.0091 0.0158
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0014
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0083 0.0102
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0014 0.0021 0.0026
Onchocerca volvulus DNA ligase 3 homolog 0.0019 0.004 0.0365
Trypanosoma brucei Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region/Zinc-finger (CX5CX6HX5H) motif containing protein, putative 0.0019 0.004 0.004
Schistosoma mansoni metabotropic glutamate receptor 0.0061 0.0201 0.0248
Loa Loa (eye worm) hypothetical protein 0.0032 0.0091 0.0158
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0032 0.0091 0.0158
Brugia malayi hypothetical protein 0.0025 0.0063 0.0077
Loa Loa (eye worm) hypothetical protein 0.0032 0.0091 0.0158
Brugia malayi Papain family cysteine protease containing protein 0.0016 0.0031 0.0038
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.2112 0.811 0.811
Echinococcus multilocularis glutamate receptor 2 0.0012 0.0013 0.0015
Schistosoma mansoni alpha-1 adrenergic receptor 0.0032 0.0091 0.0112
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0076 0.013
Schistosoma mansoni hypothetical protein 0.0041 0.0127 0.0157
Loa Loa (eye worm) hypothetical protein 0.0109 0.0389 0.0704
Loa Loa (eye worm) hypothetical protein 0.0025 0.0063 0.0106
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0048 0.0151 0.0161
Brugia malayi AMP-binding enzyme family protein 0.0048 0.0151 0.0187
Plasmodium vivax vivapain-2 0.0016 0.0031 0.0038
Loa Loa (eye worm) cysteine protease 0.0016 0.0031 0.0047
Onchocerca volvulus 0.0016 0.0031 0.0259
Schistosoma mansoni hypothetical protein 0.0032 0.0091 0.0112
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0032 0.009 0.0112
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0011 0.001 0.0012
Onchocerca volvulus 0.0233 0.0864 1
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0032 0.0091 0.0158
Echinococcus granulosus g protein coupled receptor 0.0032 0.0091 0.0112
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.0091 0.0112
Schistosoma mansoni amine GPCR 0.0032 0.0091 0.0112
Schistosoma mansoni hypothetical protein 0.0032 0.0091 0.0112
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0012 0.0013 0.0015
Brugia malayi hypothetical protein 0.0032 0.0091 0.0112
Schistosoma mansoni amine GPCR 0.0032 0.0091 0.0112
Plasmodium vivax acetyl-CoA synthetase, putative 0.0014 0.0021 0.0026
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0048 0.0151 0.0161
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0102 0.0359 0.0443
Mycobacterium leprae Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH) 0.0656 0.2496 1
Onchocerca volvulus 0.0032 0.0091 0.0966
Loa Loa (eye worm) hypothetical protein 0.0032 0.0091 0.0158
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0011 0.001 0.0012
Toxoplasma gondii glyceraldehyde-3-phosphate dehydrogenase GAPDH2 0.2112 0.811 1
Leishmania major acetyl-CoA synthetase, putative 0.0014 0.0021 0.0009
Loa Loa (eye worm) RNA binding protein 0.0064 0.0216 0.0387
Schistosoma mansoni neuropeptide receptor 0.0032 0.0091 0.0112
Trypanosoma cruzi extracellular receptor, putative 0.0012 0.0013 0.0013
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0032 0.0091 0.0112
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.002 0.0043 0.007
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.2112 0.811 0.811
Mycobacterium ulcerans acyl-CoA synthetase 0.0048 0.0151 0.0161
Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase, putative 0.2602 1 1
Loa Loa (eye worm) hypothetical protein 0.0032 0.0091 0.0158
Echinococcus multilocularis tyrosine kinase 0.0012 0.0013 0.0015
Echinococcus multilocularis cathepsin L cysteine protease 0.0016 0.0031 0.0038
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative 0.0689 0.2624 0.2624
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.1345 0.5153 0.6353
Plasmodium falciparum glyceraldehyde-3-phosphate dehydrogenase 0.2112 0.811 1
Echinococcus granulosus allatostatin A receptor 0.0032 0.0091 0.0112
Echinococcus granulosus tm gpcr rhodopsin 0.0032 0.0091 0.0112
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.0091 0.0112
Schistosoma mansoni hypothetical protein 0.0041 0.0127 0.0157
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0014
Loa Loa (eye worm) hypothetical protein 0.0032 0.0091 0.0158
Brugia malayi putative neuropeptide receptor NPR1 0.0032 0.0091 0.0112
Echinococcus multilocularis protein patched 0.0043 0.0133 0.0164
Brugia malayi Metabotropic glutamate receptor precursor. 0.0125 0.0447 0.0552
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.0091 0.0112
Loa Loa (eye worm) hypothetical protein 0.002 0.0045 0.0074
Echinococcus granulosus cpg binding protein 0.003 0.0082 0.0101
Schistosoma mansoni metabotropic glutamate receptor 0.0104 0.037 0.0456
Onchocerca volvulus 0.0032 0.0091 0.0966
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.002 0.0043 0.0031
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.0091 0.0112
Brugia malayi Cathepsin L-like cysteine proteinase 0.0011 0.001 0.0012
Leishmania major hypothetical protein, conserved 0.0025 0.0063 0.005
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0032 0.0091 0.0112
Echinococcus granulosus g-protein coupled receptor 0.0032 0.0091 0.0112
Echinococcus granulosus fmrfamide receptor 0.0032 0.0091 0.0112
Brugia malayi latrophilin 2 splice variant baaae 0.0069 0.0233 0.0288
Echinococcus multilocularis fmrfamide receptor 0.0032 0.0091 0.0112
Entamoeba histolytica cysteine protease, putative 0.0016 0.0031 0.0038
Loa Loa (eye worm) hypothetical protein 0.0032 0.009 0.0157
Brugia malayi hypothetical protein 0.0032 0.0091 0.0112
Loa Loa (eye worm) hypothetical protein 0.0032 0.0091 0.0158
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0031 0.0038
Schistosoma mansoni cpg binding protein 0.0028 0.0076 0.0094
Echinococcus granulosus Niemann Pick C1 protein 0.0143 0.0519 0.064
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1632 0.6261 0.772
Entamoeba histolytica hypothetical protein 0.0011 0.0008 0.001
Trypanosoma brucei unspecified product 0.0014 0.002 0.002
Echinococcus granulosus expressed conserved protein 0.0094 0.033 0.0407
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.0091 0.0112
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0008 0.001
Mycobacterium ulcerans hypothetical protein 0.0048 0.0151 0.0161
Loa Loa (eye worm) hypothetical protein 0.0032 0.0091 0.0158
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0016 0.0031 0.0038
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0031 0.0038
Echinococcus multilocularis g protein coupled receptor 0.0032 0.0091 0.0112
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0032 0.0091 0.0112
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0032 0.0091 0.0112
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0043 0.0043
Leishmania major 4-coumarate:coa ligase-like protein 0.0048 0.0151 0.0139
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.002 0.0043 0.0053
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0014 0.0021 0.003
Echinococcus granulosus neuropeptides capa receptor 0.0032 0.0091 0.0112
Loa Loa (eye worm) hypothetical protein 0.0069 0.0233 0.0419
Leishmania major cysteine peptidase A (CPA) 0.0016 0.0031 0.0018
Loa Loa (eye worm) hypothetical protein 0.0032 0.0091 0.0158
Plasmodium falciparum acyl-CoA synthetase 0.0036 0.0105 0.0129
Echinococcus granulosus neuropeptide receptor 0.0032 0.0091 0.0112
Echinococcus granulosus tm gpcr rhodopsin 0.0032 0.0091 0.0112
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0073 0.025 0.0308
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.01 0.0353 0.0436
Schistosoma mansoni tyrosine kinase 0.0012 0.0013 0.0015
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0043 0.0043
Trypanosoma cruzi DNA polymerase eta, putative 0.002 0.0043 0.0043
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0047 0.0147 0.0181
Schistosoma mansoni neuropeptide receptor 0.0032 0.0091 0.0112
Trichomonas vaginalis antibiotic synthetase, putative 0.0014 0.0021 0.0026
Onchocerca volvulus 0.0016 0.0031 0.0259
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0048 0.0151 0.0525
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0073 0.025 0.0238
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0032 0.0091 0.0112
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0076 0.0094
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0073 0.025 0.0308
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0208 0.0208
Brugia malayi CHE-14 protein 0.0043 0.0133 0.0164
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0043 0.0027
Loa Loa (eye worm) glyceraldehyde 3-phosphate dehydrogenase 0.1345 0.5153 0.9448
Echinococcus multilocularis sex peptide receptor 0.0032 0.0091 0.0112
Onchocerca volvulus Neuropeptide F receptor homolog 0.0032 0.0091 0.0966
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.0091 0.0112
Leishmania major glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.2112 0.811 0.8108
Schistosoma mansoni neuropeptide F-like receptor 0.0032 0.0091 0.0112
Brugia malayi larval opioid receptor 0.0032 0.0091 0.0112
Brugia malayi Cathepsin L-like precursor 0.0016 0.0031 0.0038
Loa Loa (eye worm) hypothetical protein 0.0032 0.0091 0.0158
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.002 0.0043 0.0053
Leishmania major 4-coumarate:coa ligase-like protein 0.0048 0.0151 0.0139
Entamoeba histolytica acyl-coA synthetase, putative 0.0048 0.0151 0.0187
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0031 0.0038
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.0091 0.0112
Brugia malayi Dopamine receptor 0.0032 0.0091 0.0112
Brugia malayi Cathepsin L-like precursor 0.0016 0.0031 0.0038
Loa Loa (eye worm) RGC/RGC protein kinase 0.0012 0.0013 0.0014
Entamoeba histolytica cysteine proteinase, putative 0.0016 0.0031 0.0038
Echinococcus granulosus glutamate receptor 2 0.0012 0.0013 0.0015
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0063 0.0077
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0032 0.0091 0.0112
Mycobacterium ulcerans acyl-CoA synthetase 0.0048 0.0151 0.0161
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0032 0.009 0.0112
Loa Loa (eye worm) hypothetical protein 0.0053 0.017 0.0303
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0101 0.0356 0.0439
Loa Loa (eye worm) hypothetical protein 0.0048 0.0151 0.0269
Brugia malayi follicle stimulating hormone receptor 0.0032 0.0091 0.0112
Plasmodium vivax glyceraldehyde-3-phosphate dehydrogenase, putative 0.2112 0.811 1
Echinococcus multilocularis tankyrase 0.0011 0.0008 0.001
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.0202 0.0249
Loa Loa (eye worm) hypothetical protein 0.0032 0.0091 0.0158
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.0091 0.0112
Echinococcus granulosus metabotropic glutamate receptor 2 0.0104 0.037 0.0456
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0014 0.0021 0.0021
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0032 0.0091 0.0112
Schistosoma mansoni cathepsin F (C01 family) 0.0016 0.0031 0.0038
Trypanosoma cruzi Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region/Zinc-finger (CX5CX6HX5H) motif containing protein, putative 0.0019 0.004 0.004
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0147 0.0181
Loa Loa (eye worm) hypothetical protein 0.0036 0.0105 0.0183
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0032 0.0091 0.0112
Echinococcus multilocularis poly (ADP ribose) polymerase 0.0033 0.0094 0.0116
Trichomonas vaginalis set domain proteins, putative 0.0233 0.0864 0.1066
Loa Loa (eye worm) TAR-binding protein 0.0064 0.0216 0.0387
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0032 0.0091 0.0112
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.0091 0.0112
Schistosoma mansoni opsin-like receptor 0.0032 0.0091 0.0112
Loa Loa (eye worm) hypothetical protein 0.0036 0.0105 0.0183
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.0091 0.0112
Onchocerca volvulus 0.0012 0.0013 0.0048
Echinococcus granulosus tyrosine kinase 0.0012 0.0013 0.0015
Schistosoma mansoni opsin-like receptor 0.0032 0.0091 0.0112
Trypanosoma brucei unspecified product 0.002 0.0043 0.0043
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.002 0.002
Toxoplasma gondii histone lysine methyltransferase SET1 0.0054 0.0177 0.0192
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0063 0.0063
Schistosoma mansoni tankyrase 0.0011 0.0008 0.001
Schistosoma mansoni hypothetical protein 0.0032 0.009 0.0112

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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