Detailed information for compound 886012

Basic information

Technical information
  • TDR Targets ID: 886012
  • Name: methyl 3-[(4-chloro-2-methylphenyl)sulfamoyl] thiophene-2-carboxylate
  • MW: 345.822 | Formula: C13H12ClNO4S2
  • H donors: 1 H acceptors: 3 LogP: 3.3 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: COC(=O)c1sccc1S(=O)(=O)Nc1ccc(cc1C)Cl
  • InChi: 1S/C13H12ClNO4S2/c1-8-7-9(14)3-4-10(8)15-21(17,18)11-5-6-20-12(11)13(16)19-2/h3-7,15H,1-2H3
  • InChiKey: YMLCNGSGSMUKHQ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • methyl 3-[(4-chloro-2-methyl-phenyl)sulfamoyl]thiophene-2-carboxylate
  • 3-[(4-chloro-2-methylphenyl)sulfamoyl]-2-thiophenecarboxylic acid methyl ester
  • 3-[(4-chloro-2-methyl-phenyl)sulfamoyl]thiophene-2-carboxylic acid methyl ester

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Major Facilitator Superfamily protein 0.0016 0.0205 0.0208
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0036 0.06 0.0618
Schistosoma mansoni cpg binding protein 0.003 0.0478 0.0588
Schistosoma mansoni hypothetical protein 0.0032 0.0521 0.0641
Trichomonas vaginalis myo-inositol transporter, putative 0.0016 0.0205 0.0909
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0019 0.0259 0.0265
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0016 0.0205 0.025
Leishmania major glucose transporter, lmgt1 0.0036 0.061 0.8651
Loa Loa (eye worm) hypothetical protein 0.004 0.0696 0.0717
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0036 0.0601 0.0597
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0036 0.06 0.0618
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.004 0.0696 0.0717
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.004 0.0696 0.0717
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0205 0.0909
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0007 0.0013 0.0009
Schistosoma mansoni survival motor neuron protein 0.0097 0.1867 0.2311
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.004 0.0696 0.0717
Loa Loa (eye worm) hypothetical protein 0.0028 0.0451 0.0463
Entamoeba histolytica hypothetical protein 0.007 0.1308 1
Brugia malayi beta-lactamase family protein 0.0037 0.0639 0.0658
Schistosoma mansoni nuclear hormone receptor 0.004 0.0696 0.0858
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0639 0.907
Loa Loa (eye worm) histone methyltransferase 0.0009 0.0048 0.0045
Brugia malayi hypothetical protein 0.0016 0.0205 0.0208
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0019 0.0259 0.0265
Echinococcus granulosus solute carrier family 22 0.0016 0.0205 0.0208
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0035 0.0586 0.2595
Mycobacterium leprae Probable lipase LipE 0.0037 0.0639 1
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0066 0.1224 0.1263
Brugia malayi nuclear hormone receptor family member nhr-6 0.0019 0.0259 0.0265
Loa Loa (eye worm) latrophilin receptor protein 2 0.0032 0.0521 0.0535
Schistosoma mansoni protein kinase 0.0036 0.06 0.074
Schistosoma mansoni sugar transporter 0.0016 0.0205 0.025
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0036 0.06 0.0618
Trypanosoma brucei THT1 - hexose transporter, putative 0.0036 0.061 0.8651
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0026 0.0402 0.6272
Loa Loa (eye worm) hypothetical protein 0.0019 0.0259 0.0265
Schistosoma mansoni hypothetical protein 0.0097 0.1867 0.2311
Loa Loa (eye worm) hypothetical protein 0.0016 0.0205 0.0208
Brugia malayi nuclear hormone receptor 0.0019 0.0259 0.0265
Loa Loa (eye worm) sugar transporter 0.0016 0.0205 0.0208
Trypanosoma cruzi glucose transporter, putative 0.0016 0.0205 0.2874
Loa Loa (eye worm) hypothetical protein 0.0019 0.0259 0.0265
Schistosoma mansoni sugar transporter 0.0016 0.0205 0.025
Echinococcus multilocularis cpg binding protein 0.003 0.0478 0.0491
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.004 0.0696 0.0858
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0036 0.06 0.0618
Brugia malayi Nuclear hormone receptor family member nhr-25 0.004 0.0696 0.0717
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.004 0.0696 0.0717
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0019 0.0259 0.0327
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0016 0.0205 0.0421
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0639 0.2833
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0041 0.0704 1
Trypanosoma brucei glucose transporter, putative 0.0036 0.061 0.8651
Loa Loa (eye worm) hypothetical protein 0.0016 0.0205 0.0208
Echinococcus granulosus mixed lineage leukemia protein mll 0.0007 0.0013 0.0009
Chlamydia trachomatis proline--tRNA ligase 0.0012 0.0123 0.2978
Echinococcus granulosus nuclear receptor 2DBD gamma 0.004 0.0696 0.0717
Brugia malayi Nuclear hormone receptor family member nhr-25 0.004 0.0696 0.0717
Loa Loa (eye worm) hypothetical protein 0.0016 0.0205 0.0208
Brugia malayi Nuclear hormone receptor E75 0.0019 0.0259 0.0265
Onchocerca volvulus Protein ultraspiracle homolog 0.004 0.0696 0.2954
Brugia malayi hypothetical protein 0.0019 0.0259 0.0265
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0026 0.0402 0.1783
Brugia malayi major facilitator superfamily protein 0.0016 0.0205 0.0208
Brugia malayi conserved hypotetical protein 0.0019 0.0259 0.0265
Brugia malayi Nuclear hormone receptor family member nhr-3 0.004 0.0696 0.0717
Schistosoma mansoni Tr4/Tr2 (homologue) 0.004 0.0696 0.0858
Brugia malayi hypothetical protein 0.0016 0.0205 0.0208
Brugia malayi Nuclear hormone receptor family member nhr-1 0.004 0.0696 0.0717
Schistosoma mansoni coup transcription factor 0.004 0.0696 0.0858
Plasmodium falciparum protein kinase 7 0.0328 0.6613 0.6612
Schistosoma mansoni tar DNA-binding protein 0.0066 0.1224 0.1513
Chlamydia trachomatis lysine--tRNA ligase 0.0026 0.0402 1
Treponema pallidum prolyl-tRNA synthetase 0.0012 0.0123 1
Loa Loa (eye worm) steroid hormone receptor 0.004 0.0696 0.0717
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0019 0.0259 0.0265
Echinococcus granulosus GPCR family 2 0.0032 0.0521 0.0535
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.004 0.0696 0.2954
Plasmodium falciparum calcium-dependent protein kinase 2 0.0036 0.0601 0.0597
Brugia malayi Nuclear hormone receptor family member nhr-19 0.004 0.0696 0.0717
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0239 0.4786 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0259 0.0265
Schistosoma mansoni RAR-like nuclear receptor 0.004 0.0696 0.0858
Trypanosoma brucei sugar transporter, putative 0.0016 0.0205 0.2874
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0136 0.0136
Brugia malayi Nuclear hormone receptor E75 0.0019 0.0259 0.0265
Echinococcus granulosus tar DNA binding protein 0.0066 0.1224 0.1263
Brugia malayi ecdysone receptor 0.0019 0.0259 0.0265
Loa Loa (eye worm) nuclear receptor NHR-67 0.0019 0.0259 0.0265
Leishmania major glucose transporter, lmgt3 0.0036 0.061 0.8651
Trypanosoma brucei THT1 - hexose transporter, putative 0.0036 0.061 0.8651
Brugia malayi nuclear receptor RXR 0.0019 0.0259 0.0265
Toxoplasma gondii protein kinase, putative 0.0328 0.6613 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0306 0.0313
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0007 0.0013 0.0011
Plasmodium falciparum calcium-dependent protein kinase 1 0.0036 0.0601 0.0597
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0037 0.0639 1
Echinococcus multilocularis solute carrier family 22 0.0016 0.0205 0.0208
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0205 0.0909
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0036 0.06 0.0618
Loa Loa (eye worm) hypothetical protein 0.0035 0.0586 0.0602
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0205 0.0909
Schistosoma mansoni glucose transport protein 0.0116 0.2256 0.2793
Brugia malayi nuclear receptor RXR 0.0021 0.0306 0.0313
Echinococcus granulosus lysyl tRNA synthetase 0.0026 0.0402 0.0412
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0421 0.0432
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0205 0.0909
Brugia malayi CXXC zinc finger family protein 0.0028 0.0445 0.0457
Loa Loa (eye worm) RNA binding protein 0.0066 0.1224 0.1263
Loa Loa (eye worm) hypothetical protein 0.01 0.1928 0.1992
Schistosoma mansoni hypothetical protein 0.0341 0.6888 0.8537
Trichomonas vaginalis conserved hypothetical protein 0.0116 0.2256 1
Loa Loa (eye worm) hypothetical protein 0.0037 0.0639 0.0658
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0016 0.0205 0.2874
Echinococcus multilocularis lysyl tRNA synthetase 0.0026 0.0402 0.0412
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0205 0.0909
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0205 0.0909
Schistosoma mansoni retinoic acid receptor RXR 0.004 0.0696 0.0858
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0205 0.0909
Toxoplasma gondii TIM10 family protein, putative 0.005 0.089 0.1341
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.004 0.0696 0.0717
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0032 0.0521 0.0535
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0036 0.06 0.0618
Giardia lamblia Lysyl-tRNA synthetase 0.0026 0.0402 0.6849
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0639 0.0788
Schistosoma mansoni sugar transporter 0.0016 0.0205 0.025
Schistosoma mansoni zinc finger protein 0.0019 0.0259 0.0317
Trypanosoma cruzi hexose transporter, putative 0.002 0.0274 0.386
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0019 0.0259 0.0327
Loa Loa (eye worm) hypothetical protein 0.004 0.0696 0.0717
Loa Loa (eye worm) DR-78 0.0019 0.0259 0.0265
Toxoplasma gondii transporter, major facilitator family protein 0.0016 0.0205 0.0305
Echinococcus granulosus calcium dependent protein kinase 0.0033 0.0555 0.0571
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0116 0.2256 0.2332
Plasmodium vivax hexose transporter 0.0116 0.2256 0.2253
Echinococcus granulosus FTZ F1 alpha 0.004 0.0696 0.0717
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.0048 0.0045
Echinococcus granulosus retinoic acid receptor rxr beta a 0.004 0.0696 0.0717
Schistosoma mansoni nuclear receptor 0.0019 0.0259 0.0317
Brugia malayi nuclear receptor NHR-88 0.0019 0.0259 0.0265
Loa Loa (eye worm) hypothetical protein 0.0026 0.0411 0.0421
Brugia malayi beta-lactamase 0.0037 0.0639 0.0658
Echinococcus granulosus thyroid hormone receptor alpha 0.0019 0.0259 0.0265
Loa Loa (eye worm) hypothetical protein 0.0035 0.0586 0.0602
Loa Loa (eye worm) hypothetical protein 0.0013 0.0136 0.0136
Schistosoma mansoni thyroid hormone receptor 0.004 0.0696 0.0858
Leishmania major glucose transporter/membrane transporter D2, putative 0.0036 0.061 0.8651
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0016 0.0205 0.0421
Brugia malayi Nuclear hormone receptor family member nhr-31 0.004 0.0696 0.0717
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0205 0.0909
Leishmania major hypothetical protein, conserved 0.0016 0.0205 0.2874
Onchocerca volvulus 0.0027 0.0421 0.1297
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.004 0.0696 0.0717
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0306 0.0313
Loa Loa (eye worm) hypothetical protein 0.0036 0.06 0.0618
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.061 0.2703
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0205 0.0909
Trypanosoma brucei glucose transporter, putative 0.0036 0.061 0.8651
Loa Loa (eye worm) hypothetical protein 0.0016 0.0205 0.0208
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0188 0.3726 0.5632
Loa Loa (eye worm) hypothetical protein 0.0027 0.0421 0.0432
Echinococcus granulosus beta LACTamase domain containing family member 0.0037 0.0639 0.0658
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0035 0.0586 0.0721
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0022 0.0322 0.0665
Brugia malayi Mitochondrial import inner membrane translocase subunit TIM10 0.005 0.089 0.0917
Mycobacterium tuberculosis Conserved protein 0.0037 0.0639 0.1328
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0116 0.2256 0.2332
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0639 0.2833
Echinococcus granulosus synaptic vesicle 2 protein 0.0016 0.0205 0.0208
Plasmodium vivax CDK-related protein kinase 6, putative 0.0493 1 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0259 0.0265
Schistosoma mansoni nuclear receptor nhr-48 0.0019 0.0259 0.0317
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.061 0.2703
Schistosoma mansoni hypothetical protein 0.0341 0.6888 0.8537
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0032 0.0521 0.0535
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0205 0.0909
Brugia malayi nuclear hormone receptor 0.004 0.0696 0.0717
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0036 0.0601 0.0903
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0036 0.0601 0.0903
Loa Loa (eye worm) hypothetical protein 0.0021 0.0306 0.0313
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0205 0.0909
Schistosoma mansoni protein kinase 0.0036 0.06 0.074
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0023 0.0337 0.1492
Loa Loa (eye worm) hypothetical protein 0.004 0.0696 0.0717
Mycobacterium ulcerans integral membrane transport protein 0.0016 0.0205 0.3169
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0019 0.0259 0.0265
Trichomonas vaginalis glucose transporter, putative 0.0036 0.061 0.2703
Schistosoma mansoni lamin 0.0027 0.0421 0.0517
Trichomonas vaginalis esterase, putative 0.0037 0.0639 0.2833
Loa Loa (eye worm) hypothetical protein 0.0019 0.0259 0.0265
Brugia malayi steroid hormone receptor 0.004 0.0696 0.0717
Plasmodium vivax hypothetical protein, conserved 0.0037 0.0639 0.0636
Entamoeba histolytica hypothetical protein 0.007 0.1308 1
Mycobacterium ulcerans hypothetical protein 0.0037 0.0639 1
Trichomonas vaginalis sugar transport protein, putative 0.0016 0.0205 0.0909
Trichomonas vaginalis glucose transporter, putative 0.0036 0.061 0.2703
Mycobacterium ulcerans lipase LipD 0.0037 0.0639 1
Brugia malayi TAR-binding protein 0.0066 0.1224 0.1263
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0639 0.0788
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0032 0.0521 0.0535
Plasmodium falciparum proline--tRNA ligase 0.0041 0.0704 0.0701
Brugia malayi Nuclear hormone receptor family member nhr-49 0.004 0.0696 0.0717
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0036 0.06 0.0618
Loa Loa (eye worm) hypothetical protein 0.0016 0.0205 0.0208
Trypanosoma cruzi sugar transporter, putative 0.0016 0.0205 0.2874
Loa Loa (eye worm) hypothetical protein 0.0019 0.0259 0.0265
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0021 0.0306 0.0313
Plasmodium falciparum calcium-dependent protein kinase 4 0.0036 0.0601 0.0597
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0035 0.0586 0.0602
Echinococcus multilocularis beta LACTamase domain containing family member 0.0037 0.0639 0.0658
Mycobacterium tuberculosis Probable esterase LipL 0.0037 0.0639 0.1328
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0026 0.0402 0.5689
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0041 0.0704 1
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0026 0.0402 0.6272
Echinococcus granulosus Sugar transporter ERD6 protein 0.0016 0.0205 0.0208
Brugia malayi Sugar transporter family protein 0.0016 0.0205 0.0208
Loa Loa (eye worm) hypothetical protein 0.0016 0.0205 0.0208
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0205 0.0909
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.004 0.0696 0.0717
Loa Loa (eye worm) nuclear hormone receptor 0.0019 0.0259 0.0265
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0205 0.0909
Echinococcus granulosus expressed protein 0.005 0.089 0.0917
Schistosoma mansoni lysyl-tRNA synthetase 0.0026 0.0402 0.0494
Loa Loa (eye worm) hypothetical protein 0.0016 0.0205 0.0208
Mycobacterium tuberculosis Probable hydrolase 0.0037 0.0639 0.1328
Brugia malayi tailless protein 0.0019 0.0259 0.0265
Loa Loa (eye worm) hypothetical protein 0.0019 0.0259 0.0265
Brugia malayi Sugar transporter family protein 0.0016 0.0205 0.0208
Onchocerca volvulus 0.0019 0.0259 0.0327
Loa Loa (eye worm) hypothetical protein 0.0019 0.0259 0.0265
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0032 0.0521 0.0535
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0014 0.0164 0.0165
Loa Loa (eye worm) hypothetical protein 0.004 0.0696 0.0717
Mycobacterium tuberculosis Probable lipase LipD 0.0037 0.0639 0.1328
Loa Loa (eye worm) hypothetical protein 0.0019 0.0259 0.0265
Schistosoma mansoni cpg binding protein 0.003 0.0478 0.0588
Mycobacterium tuberculosis Conserved protein 0.0037 0.0639 0.1328
Echinococcus multilocularis geminin 0.0341 0.6888 0.7126
Echinococcus multilocularis thyroid hormone receptor alpha 0.004 0.0696 0.0717
Echinococcus multilocularis survival motor neuron protein 1 0.0476 0.9664 1
Schistosoma mansoni hypothetical protein 0.0032 0.0521 0.0641
Loa Loa (eye worm) hypothetical protein 0.0037 0.0639 0.0658
Brugia malayi RNA binding protein 0.0066 0.1224 0.1263
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.01 0.1928 0.1992
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.004 0.0696 0.0717
Schistosoma mansoni nuclear hormone receptor 0.0019 0.0259 0.0317
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0205 0.0909
Loa Loa (eye worm) hypothetical protein 0.0021 0.0306 0.0313
Plasmodium falciparum hexose transporter 0.0116 0.2256 0.2253
Trypanosoma brucei glucose transporter 1E 0.0036 0.061 0.8651
Mycobacterium tuberculosis Conserved protein 0.0037 0.0639 0.1328
Echinococcus granulosus Nuclear hormone receptor HR96 0.0019 0.0259 0.0265
Leishmania major myo-inositol/proton symporter (MIT) 0.0016 0.0205 0.2874
Loa Loa (eye worm) hypothetical protein 0.004 0.0696 0.0717
Brugia malayi hypothetical protein 0.0476 0.9664 1
Schistosoma mansoni transcription factor LCR-F1 0.007 0.1308 0.1617
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0165 0.0167
Entamoeba histolytica protein kinase, putative 0.0036 0.06 0.4576
Leishmania major glucose transporter, lmgt2 0.0036 0.061 0.8651
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0012 0.0123 0.1868
Loa Loa (eye worm) hypothetical protein 0.004 0.0696 0.0717
Loa Loa (eye worm) hypothetical protein 0.0016 0.0205 0.0208
Brugia malayi beta-lactamase family protein 0.0037 0.0639 0.0658
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0019 0.0259 0.0317
Schistosoma mansoni mitochondrial import inner membrane translocase subunit tim10 0.005 0.089 0.1099
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0035 0.0586 0.0602
Echinococcus granulosus solute carrier family 22 0.0016 0.0205 0.0208
Trypanosoma cruzi hexose transporter, putative 0.0016 0.0205 0.2874
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0035 0.0586 0.0602
Plasmodium vivax mitochondrial import inner membrane translocase subunit TIM10, putative 0.005 0.089 0.0887
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0021 0.0306 0.0313
Brugia malayi F/Y-rich N-terminus family protein 0.0009 0.0045 0.0043
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0022 0.0322 0.5008
Brugia malayi major facilitator superfamily protein 0.0016 0.0205 0.0208
Loa Loa (eye worm) hypothetical protein 0.0068 0.1277 0.1318
Onchocerca volvulus 0.0037 0.0639 0.2611
Trypanosoma brucei glucose transporter, putative 0.0036 0.061 0.8651
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0205 0.0909
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0035 0.0586 0.4463
Mycobacterium tuberculosis Probable lipase LipE 0.0037 0.0639 0.1328
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0035 0.0586 0.9158
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0205 0.0909
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0007 0.0013 0.0009
Toxoplasma gondii sugar transporter ST3 0.0016 0.0205 0.0305
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0036 0.0601 0.0597
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.007 0.1308 0.135
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0205 0.0909
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0036 0.06 0.0618
Loa Loa (eye worm) transport to inner mitochondrial membrane family member 0.005 0.089 0.0917
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0037 0.0639 0.1328
Leishmania major lysyl-tRNA synthetase, putative 0.0026 0.0402 0.5689
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0639 0.907
Leishmania major protein kinase, putative 0.0036 0.06 0.8517
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0021 0.0306 0.0313
Toxoplasma gondii facilitative glucose transporter GT1 0.0116 0.2256 0.3408
Entamoeba histolytica hypothetical protein 0.007 0.1308 1
Echinococcus granulosus General substrate transporter 0.01 0.1921 0.1984
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0639 0.2833
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0026 0.0402 0.6272
Trypanosoma cruzi hexose transporter, putative 0.0036 0.061 0.8651
Trypanosoma brucei THT1 - hexose transporter, putative 0.0036 0.061 0.8651
Echinococcus granulosus ecdysone induced protein 78C 0.004 0.0696 0.0717
Schistosoma mansoni tar DNA-binding protein 0.0066 0.1224 0.1513
Loa Loa (eye worm) hypothetical protein 0.0016 0.0205 0.0208
Brugia malayi nuclear receptor NHR-88 0.004 0.0696 0.0717
Echinococcus multilocularis musashi 0.0027 0.0421 0.0432
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0205 0.0909
Toxoplasma gondii lysine-tRNA ligase 0.0026 0.0402 0.0603
Loa Loa (eye worm) hypothetical protein 0.004 0.0696 0.0717
Schistosoma mansoni glucose transport protein 0.0116 0.2256 0.2793
Echinococcus granulosus lamin dm0 0.0027 0.0421 0.0432
Echinococcus multilocularis ecdysone induced protein 78C 0.004 0.0696 0.0717
Trypanosoma cruzi hexose transporter, putative 0.0036 0.061 0.8651
Echinococcus multilocularis tar DNA binding protein 0.0066 0.1224 0.1263
Onchocerca volvulus 0.0037 0.0639 0.2611
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0036 0.0601 0.0597
Loa Loa (eye worm) beta-lactamase 0.0037 0.0639 0.0658
Brugia malayi Major Facilitator Superfamily protein 0.0016 0.0205 0.0208
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0036 0.06 0.0618
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0205 0.0909
Plasmodium falciparum calcium-dependent protein kinase 5 0.0036 0.0601 0.0597
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.004 0.0696 0.0717
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0205 0.0909
Echinococcus granulosus solute carrier family 22 0.0016 0.0205 0.0208
Mycobacterium leprae conserved hypothetical protein 0.0037 0.0639 1
Plasmodium vivax sugar transporter, putative 0.0016 0.0205 0.0201
Plasmodium falciparum mitochondrial import inner membrane translocase subunit TIM10, putative 0.005 0.089 0.0887
Plasmodium falciparum mitogen-activated protein kinase 2 0.0188 0.3726 0.3724
Onchocerca volvulus 0.0037 0.0639 0.2611
Echinococcus granulosus cpg binding protein 0.003 0.0478 0.0491
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0019 0.0259 0.0265
Loa Loa (eye worm) hypothetical protein 0.0019 0.0259 0.0265
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0205 0.0909
Mycobacterium ulcerans beta-lactamase 0.0037 0.0639 1
Loa Loa (eye worm) major facilitator superfamily transporter 0.0016 0.0205 0.0208
Loa Loa (eye worm) hypothetical protein 0.0032 0.0521 0.0535
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0016 0.0205 0.3169
Echinococcus granulosus nuclear receptor 2DBD gamma 0.004 0.0696 0.0717
Schistosoma mansoni nuclear receptor 0.0019 0.0259 0.0317
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0205 0.0909
Echinococcus multilocularis solute carrier family 22 0.0016 0.0205 0.0208
Schistosoma mansoni cpg binding protein 0.0028 0.0445 0.0547
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0421 0.0432
Trichomonas vaginalis CAMK family protein kinase 0.0036 0.06 0.2661
Plasmodium vivax calcium-dependent protein kinase, putative 0.0036 0.0601 0.0597
Toxoplasma gondii histone lysine methyltransferase SET1 0.0053 0.096 0.1447
Echinococcus granulosus Nuclear hormone receptor HR96 0.0019 0.0259 0.0265
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0016 0.0205 0.3169
Trypanosoma brucei glucose transporter 2A 0.0036 0.061 0.8651
Brugia malayi hypothetical protein 0.0016 0.0205 0.0208
Toxoplasma gondii mitochondrial import inner membrane translocase subunit TIM10, putative 0.005 0.089 0.1341
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0205 0.0909
Brugia malayi Nuclear hormone receptor family member nhr-19 0.004 0.0696 0.0717
Trypanosoma brucei glucose transporter, putative 0.0036 0.061 0.8651
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0016 0.0205 1
Loa Loa (eye worm) major facilitator superfamily transporter 0.0016 0.0205 0.0208
Toxoplasma gondii sugar transporter ST2 0.0016 0.0205 0.0305
Trichomonas vaginalis threonyl-tRNA synthetase, putative 0.0007 0.0004 0.0017
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0205 0.0909
Brugia malayi photoreceptor-specific nuclear receptor 0.004 0.0696 0.0717
Loa Loa (eye worm) TAR-binding protein 0.0066 0.1224 0.1263
Trichomonas vaginalis sugar transporter, putative 0.0036 0.061 0.2703
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0639 0.2833
Echinococcus multilocularis synaptic vesicle 2 protein 0.0016 0.0205 0.0208
Loa Loa (eye worm) hypothetical protein 0.004 0.0696 0.0717
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.004 0.0696 0.0717
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0205 0.0909
Schistosoma mansoni tar DNA-binding protein 0.0066 0.1224 0.1513
Schistosoma mansoni intermediate filament proteins 0.0027 0.0421 0.0517
Loa Loa (eye worm) hypothetical protein 0.0012 0.0125 0.0126
Giardia lamblia Sugar-proton symporter 0.0016 0.0205 0.346
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.004 0.0696 0.0717
Plasmodium falciparum calcium-dependent protein kinase 3 0.0036 0.0601 0.0597
Loa Loa (eye worm) hypothetical protein 0.0021 0.0306 0.0313
Trypanosoma cruzi hexose transporter 0.0036 0.061 0.8651
Echinococcus multilocularis General substrate transporter 0.01 0.1921 0.1984
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0639 0.2833
Loa Loa (eye worm) hypothetical protein 0.0037 0.0639 0.0658
Brugia malayi lysyl-tRNA synthetase 0.0026 0.0402 0.0412
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.007 0.1308 0.135
Onchocerca volvulus 0.0097 0.1867 1
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0205 0.0909
Loa Loa (eye worm) hypothetical protein 0.0476 0.9664 1
Echinococcus granulosus dnaJ subfamily B 0.0399 0.8068 0.8348
Brugia malayi hypothetical protein 0.007 0.1308 0.135
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0019 0.0259 0.0265
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.004 0.0696 0.0858
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.004 0.0696 0.0858
Brugia malayi RNA recognition motif domain containing protein 0.0066 0.1224 0.1263
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0116 0.2256 0.2332
Onchocerca volvulus 0.004 0.0696 0.2954
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0205 0.0909
Loa Loa (eye worm) hypothetical protein 0.0016 0.0205 0.0208
Schistosoma mansoni lamin 0.0027 0.0421 0.0517
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0116 0.2256 0.2332
Trypanosoma cruzi hexose transporter, putative 0.0036 0.061 0.8651
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0016 0.0205 0.0208
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.004 0.0696 0.0717
Brugia malayi hypothetical protein 0.0021 0.0306 0.0313
Brugia malayi intermediate filament protein 0.0027 0.0421 0.0432
Schistosoma mansoni tar DNA-binding protein 0.0066 0.1224 0.1513
Loa Loa (eye worm) sugar transporter 0.0116 0.2256 0.2332
Plasmodium falciparum lysine--tRNA ligase 0.0026 0.0402 0.0399
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0041 0.0704 1
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0421 0.0432
Schistosoma mansoni hypothetical protein 0.0032 0.0521 0.0641
Echinococcus multilocularis lamin dm0 0.0027 0.0421 0.0432
Brugia malayi Nuclear hormone receptor-like 1 0.004 0.0696 0.0717
Schistosoma mansoni hypothetical protein 0.007 0.1308 0.1617
Schistosoma mansoni steroid hormone receptor ad4bp 0.004 0.0696 0.0858
Echinococcus multilocularis lamin 0.0027 0.0421 0.0432
Echinococcus multilocularis nuclear receptor nhr 48 0.0019 0.0259 0.0265
Schistosoma mansoni serine/threonine protein kinase 0.0036 0.06 0.074
Trypanosoma brucei glucose transporter, putative 0.0036 0.061 0.8651
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0037 0.0639 0.1328
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0036 0.06 0.0618
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0306 0.0313
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0205 0.0909
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0306 0.0375
Schistosoma mansoni hypothetical protein 0.0399 0.8068 1
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0097 0.1867 0.1929
Loa Loa (eye worm) hypothetical protein 0.0016 0.0205 0.0208
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0205 0.0909
Entamoeba histolytica protein kinase, putative 0.0036 0.06 0.4576
Echinococcus multilocularis dnaJ subfamily B 0.0399 0.8068 0.8348
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0205 0.0909
Brugia malayi hypothetical protein 0.0021 0.0306 0.0313
Leishmania major hypothetical protein, conserved 0.0037 0.0639 0.907
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.004 0.0696 0.0717
Loa Loa (eye worm) hypothetical protein 0.0021 0.0306 0.0313
Schistosoma mansoni lysyl-tRNA synthetase 0.0026 0.0402 0.0494
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0019 0.0259 0.0265
Loa Loa (eye worm) hypothetical protein 0.0016 0.0205 0.0208
Onchocerca volvulus 0.0027 0.0421 0.1297
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0036 0.0601 0.0903
Brugia malayi nuclear receptor NHR-67 0.0019 0.0259 0.0265
Brugia malayi latrophilin 2 splice variant baaae 0.0068 0.1277 0.1318
Brugia malayi orphan nuclear receptor NR2E1 0.0019 0.0259 0.0265
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.004 0.0696 0.0717
Echinococcus multilocularis expressed protein 0.005 0.089 0.0917
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0445 0.0457
Onchocerca volvulus 0.0028 0.0445 0.1444
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0037 0.0639 0.0658
Schistosoma mansoni nuclear hormone receptor 0.0019 0.0259 0.0317
Schistosoma mansoni hypothetical protein 0.0068 0.1277 0.1579
Toxoplasma gondii sugar transporter ST1 0.0016 0.0205 0.0305
Loa Loa (eye worm) hypothetical protein 0.0037 0.0639 0.0658
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0116 0.2256 0.2332
Trichomonas vaginalis sugar transporter, putative 0.0036 0.061 0.2703
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0036 0.06 0.8517
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0205 0.0909
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0007 0.0013 0.0009
Brugia malayi Steroid receptor seven-up type 2 0.004 0.0696 0.0717
Schistosoma mansoni sugar transporter 0.0016 0.0205 0.025
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0205 0.0909
Echinococcus granulosus nuclear receptor nhr 48 0.0019 0.0259 0.0265
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0037 0.0639 0.0658
Trypanosoma brucei glucose transporter, putative 0.0036 0.061 0.8651
Echinococcus granulosus geminin 0.0341 0.6888 0.7126
Onchocerca volvulus 0.0019 0.0259 0.0327
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0205 0.0909
Loa Loa (eye worm) hypothetical protein 0.0019 0.0259 0.0265
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0021 0.0306 0.0375
Schistosoma mansoni retinoid-x-receptor (RXR) 0.004 0.0696 0.0858
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0639 0.907
Entamoeba histolytica hypothetical protein 0.0026 0.0402 0.3057
Schistosoma mansoni hypothetical protein 0.0032 0.0521 0.0641
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0165 0.0167
Schistosoma mansoni tar DNA-binding protein 0.0066 0.1224 0.1513
Entamoeba histolytica hypothetical protein 0.007 0.1308 1
Echinococcus multilocularis GPCR, family 2 0.0032 0.0521 0.0535
Loa Loa (eye worm) hypothetical protein 0.0037 0.0639 0.0658
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0136 0.0136
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0019 0.0259 0.0265
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0205 0.0909
Brugia malayi Nuclear hormone receptor family member nhr-14 0.004 0.0696 0.0717
Echinococcus multilocularis solute carrier family 22 0.0016 0.0205 0.0208
Brugia malayi Major Facilitator Superfamily protein 0.0016 0.0205 0.0208
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0041 0.0704 1
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.004 0.0696 0.0858
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0032 0.0521 0.0535
Brugia malayi hypothetical protein 0.0019 0.0259 0.0265
Loa Loa (eye worm) hypothetical protein 0.0019 0.0259 0.0265
Plasmodium vivax proline--tRNA ligase, putative 0.0041 0.0704 0.0701
Schistosoma mansoni thyroid hormone receptor 0.004 0.0696 0.0858
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0205 0.0909
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.004 0.0696 0.0717
Schistosoma mansoni glucose transport protein 0.0116 0.2256 0.2793
Toxoplasma gondii ABC1 family protein 0.0037 0.0639 0.0961
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.004 0.0696 0.0717
Brugia malayi Sugar transporter family protein 0.0116 0.2256 0.2332
Echinococcus multilocularis calcium dependent protein kinase 0.0033 0.0555 0.0571
Schistosoma mansoni protein kinase 0.0036 0.06 0.074
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0016 0.0205 0.0201
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0041 0.0704 0.106
Echinococcus granulosus survival motor neuron protein 1 0.0476 0.9664 1
Mycobacterium ulcerans sugar transporter 0.0016 0.0205 0.3169
Loa Loa (eye worm) pigment dispersing factor receptor c 0.01 0.1928 0.1992
Trichomonas vaginalis glucose transporter, putative 0.0016 0.0205 0.0909
Loa Loa (eye worm) hypothetical protein 0.0037 0.0639 0.0658
Echinococcus multilocularis solute carrier family 22 0.0016 0.0205 0.0208
Brugia malayi Cam kinase protein 1 0.0036 0.06 0.0618
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0035 0.0586 0.0602
Mycobacterium ulcerans esterase/lipase LipP 0.0037 0.0639 1
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0205 0.0909
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.0048 0.0045
Echinococcus granulosus solute carrier family 22 0.0016 0.0205 0.0208
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0205 0.0909
Echinococcus granulosus lamin 0.0027 0.0421 0.0432
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0022 0.0322 0.0665
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0116 0.2256 0.2332
Brugia malayi ecdysteroid receptor 0.004 0.0696 0.0717
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0036 0.06 0.0618
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0019 0.0259 0.0317
Brugia malayi Nuclear hormone receptor family member nhr-41 0.004 0.0696 0.0717
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0205 0.0909
Echinococcus multilocularis FTZ F1 alpha 0.004 0.0696 0.0717
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0019 0.0259 0.0265
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0116 0.2256 0.2332
Brugia malayi Nuclear hormone receptor family member nhr-40 0.004 0.0696 0.0717
Echinococcus granulosus intermediate filament protein 0.0027 0.0421 0.0432
Loa Loa (eye worm) hypothetical protein 0.0016 0.0205 0.0208
Loa Loa (eye worm) hypothetical protein 0.0012 0.0125 0.0126
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0037 0.0639 0.1328
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0059 0.1091 0.1348
Schistosoma mansoni hypothetical protein 0.0116 0.2256 0.2793
Trypanosoma brucei glucose transporter, putative 0.0036 0.061 0.8651
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0116 0.2256 0.2332
Schistosoma mansoni glucose transporter 0.0016 0.0205 0.025
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.004 0.0696 0.0717
Brugia malayi Latrophilin receptor protein 2 0.0032 0.0521 0.0535
Loa Loa (eye worm) hypothetical protein 0.0016 0.0205 0.0208
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.004 0.0696 0.0717
Brugia malayi nuclear hormone receptor family member odr-7 0.0019 0.0259 0.0265
Plasmodium vivax lysine--tRNA ligase, putative 0.0026 0.0402 0.0399
Loa Loa (eye worm) hypothetical protein 0.0019 0.0259 0.0265
Onchocerca volvulus Bile acid receptor homolog 0.004 0.0696 0.2954
Giardia lamblia Prolyl-tRNA synthetase 0.0035 0.0586 1
Loa Loa (eye worm) hypothetical protein 0.0016 0.0205 0.0208
Trypanosoma brucei glucose transporter, putative 0.0036 0.061 0.8651
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0205 0.0909
Loa Loa (eye worm) hypothetical protein 0.0026 0.0402 0.0412
Brugia malayi Calcitonin receptor-like protein seb-1 0.01 0.1928 0.1992
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0041 0.0704 1
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0026 0.0402 0.5689
Giardia lamblia Hexose transporter 0.0016 0.0205 0.346
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0205 0.0909
Trichomonas vaginalis sugar transporter, putative 0.0036 0.061 0.2703
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0035 0.0586 0.0721
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0188 0.3726 0.3724
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.004 0.0696 0.0717

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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