Detailed information for compound 922873

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 450.513 | Formula: C22H22N6O3S
  • H donors: 4 H acceptors: 7 LogP: 1.52 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCNC(=O)Nc1sc2c(n1)cc(cc2c1ccccn1)c1cnc(nc1)[C@H]([C@H](O)C)O
  • InChi: 1S/C22H22N6O3S/c1-3-23-21(31)28-22-27-17-9-13(14-10-25-20(26-11-14)18(30)12(2)29)8-15(19(17)32-22)16-6-4-5-7-24-16/h4-12,18,29-30H,3H2,1-2H3,(H2,23,27,28,31)/t12-,18+/m1/s1
  • InChiKey: ULPRFGALBOSKOA-XIKOKIGWSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Cytochrome P450 family protein 0.0007 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0008 0.0027 0.008
Echinococcus granulosus pyruvate kinase 0.0035 0.0556 0.1609
Schistosoma mansoni voltage-gated potassium channel 0.0011 0.0095 0.0286
Echinococcus granulosus rhodopsin orphan GPCR 0.0068 0.1208 0.3571
Loa Loa (eye worm) cyclin domain-containing protein 0.0014 0.0149 0.0445
Brugia malayi Cytochrome P450 family protein 0.0007 0.0022 0.0022
Onchocerca volvulus 0.0068 0.1208 0.5753
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0271 0.1323
Schistosoma mansoni hypothetical protein 0.0068 0.1208 0.3613
Toxoplasma gondii cyclin 4, putative 0.0014 0.0149 0.1891
Loa Loa (eye worm) hypothetical protein 0.0068 0.1208 0.3613
Giardia lamblia Pyruvate kinase 0.0035 0.0556 0.2721
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0271 0.1323
Brugia malayi Cytochrome P450 family protein 0.0007 0.0022 0.0022
Trichomonas vaginalis cyclins, putative 0.0111 0.2045 1
Loa Loa (eye worm) hypothetical protein 0.0068 0.1208 0.3613
Schistosoma mansoni voltage-gated potassium channel 0.0042 0.0697 0.2086
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0008 0.0027 0.0013
Echinococcus granulosus alpha 1A adrenergic receptor 0.0068 0.1208 0.3571
Giardia lamblia DINP protein human, muc B family 0.002 0.0271 0.1323
Brugia malayi Pyruvate kinase, muscle isozyme 0.0035 0.0556 0.0556
Leishmania major pyruvate kinase 0.0035 0.0556 0.2721
Echinococcus multilocularis cyclins 0.0057 0.0999 0.2944
Schistosoma mansoni terminal deoxycytidyl transferase 0.002 0.0271 0.081
Brugia malayi hypothetical protein 0.0068 0.1208 0.1208
Giardia lamblia Hypothetical protein 0.0014 0.0149 0.0728
Echinococcus multilocularis dna polymerase eta 0.002 0.0271 0.0748
Leishmania major DNA polymerase kappa, putative 0.002 0.0271 0.1323
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0035 0.0556 1
Toxoplasma gondii cyclin domain protein, cyclin H family protein 0.0014 0.0149 0.1891
Echinococcus granulosus tm gpcr rhodopsin 0.0068 0.1208 0.3571
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0068 0.1208 0.3613
Echinococcus granulosus cyclin B 0.0111 0.2045 0.6093
Schistosoma mansoni serine/threonine protein kinase 0.0047 0.0787 0.2354
Echinococcus granulosus g protein coupled receptor 0.0068 0.1208 0.3571
Brugia malayi RE15519p 0.0068 0.1208 0.1208
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0068 0.1208 0.1208
Loa Loa (eye worm) cyclin domain-containing protein 0.0014 0.0149 0.0445
Brugia malayi Nuclear hormone receptor family member nhr-31 0.001 0.0073 0.0073
Loa Loa (eye worm) steroid hormone receptor 0.001 0.0073 0.0219
Schistosoma mansoni g1/s-specific cyclin C 0.0014 0.0149 0.0445
Onchocerca volvulus 0.0068 0.1208 0.5753
Brugia malayi hypothetical protein 0.0014 0.0149 0.0149
Trichomonas vaginalis CMGC family protein kinase 0.0047 0.0787 0.3766
Brugia malayi nuclear hormone receptor 0.001 0.0073 0.0073
Schistosoma mansoni amine GPCR 0.0068 0.1208 0.3613
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0068 0.1208 0.3613
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0068 0.1208 0.5753
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0068 0.1208 0.3613
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0271 0.1323
Trypanosoma brucei DNA polymerase eta, putative 0.002 0.0271 0.1323
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0008 0.0027 0.0013
Echinococcus granulosus biogenic amine 5HT receptor 0.0068 0.1208 0.3571
Plasmodium vivax pyruvate kinase, putative 0.0035 0.0556 0.7073
Echinococcus multilocularis cyclin b3 0.0057 0.0999 0.2944
Echinococcus multilocularis netrin receptor unc 5 0.0015 0.0171 0.0447
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0068 0.1208 0.3571
Onchocerca volvulus 0.0068 0.1208 0.5753
Schistosoma mansoni cyclin d 0.0014 0.0149 0.0445
Trichomonas vaginalis cyclin D, putative 0.0057 0.0999 0.482
Trypanosoma cruzi mitotic cyclin, putative 0.0014 0.0149 0.0728
Brugia malayi steroid hormone receptor 0.001 0.0073 0.0073
Trichomonas vaginalis CMGC family protein kinase 0.0047 0.0787 0.3766
Schistosoma mansoni cyclin B3 0.0177 0.3342 1
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.001 0.0073 0.0219
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0038 0.0628 0.1826
Echinococcus granulosus neuropeptides capa receptor 0.0068 0.1208 0.3571
Schistosoma mansoni DNA polymerase eta 0.002 0.0271 0.081
Loa Loa (eye worm) neuropeptide F receptor 0.0068 0.1208 0.3613
Echinococcus multilocularis cyclin G2 0.0014 0.0149 0.0382
Trypanosoma brucei cyclin 3 0.0014 0.0149 0.0728
Trichomonas vaginalis cyclin B, putative 0.0057 0.0999 0.482
Schistosoma mansoni pyruvate kinase 0.0035 0.0556 0.1665
Loa Loa (eye worm) hypothetical protein 0.0111 0.2045 0.6119
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0007 0.0022 0.0398
Trypanosoma brucei cytochrome P450, putative 0.0007 0.0022 0.0108
Loa Loa (eye worm) hypothetical protein 0.0068 0.1208 0.3613
Schistosoma mansoni amine GPCR 0.0068 0.1208 0.3613
Echinococcus multilocularis dna polymerase kappa 0.002 0.0271 0.0748
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0271 0.1323
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.001 0.0073 0.0219
Plasmodium falciparum pyruvate kinase 2 0.0018 0.0226 0.2265
Echinococcus granulosus cyclin B3 1 0.0057 0.0999 0.2944
Schistosoma mansoni biogenic amine receptor 0.0068 0.1208 0.3613
Echinococcus granulosus biogenic amine 5HT receptor 0.0068 0.1208 0.3571
Echinococcus multilocularis orexin receptor type 2 0.0068 0.1208 0.3571
Brugia malayi Nuclear hormone receptor-like 1 0.001 0.0073 0.0073
Loa Loa (eye worm) hypothetical protein 0.0068 0.1208 0.3613
Echinococcus multilocularis rhodopsin orphan GPCR 0.0068 0.1208 0.3571
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0007 0.0022 0.0108
Schistosoma mansoni coup transcription factor 0.001 0.0073 0.0219
Trypanosoma brucei pyruvate kinase 1 0.0035 0.0556 0.2721
Brugia malayi Uncoordinated protein 44 0.0015 0.0171 0.0171
Echinococcus multilocularis cyclin y 0.0014 0.0149 0.0382
Brugia malayi Steroid receptor seven-up type 2 0.001 0.0073 0.0073
Toxoplasma gondii pyruvate kinase PyK1 0.0035 0.0556 0.7073
Brugia malayi cell division control protein 2 homolog 0.0047 0.0787 0.0787
Loa Loa (eye worm) hypothetical protein 0.0068 0.1208 0.3613
Brugia malayi Cyclin C 0.0014 0.0149 0.0149
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0068 0.1208 0.3613
Onchocerca volvulus 0.0068 0.1208 0.5753
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0068 0.1208 0.3613
Trichomonas vaginalis pyruvate kinase, putative 0.0035 0.0556 0.2625
Brugia malayi Cytochrome P450 family protein 0.0007 0.0022 0.0022
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0007 0.0022 0.0398
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0068 0.1208 0.3571
Trichomonas vaginalis cyclin B, putative 0.0111 0.2045 1
Onchocerca volvulus 0.0068 0.1208 0.5753
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0015 0.0171 0.0447
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.002 0.0271 0.081
Brugia malayi photoreceptor-specific nuclear receptor 0.001 0.0073 0.0073
Brugia malayi larval opioid receptor 0.0068 0.1208 0.1208
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0077 0.1375 0.4076
Onchocerca volvulus Pyruvate kinase homolog 0.0035 0.0556 0.2451
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0271 0.1323
Brugia malayi AKH receptor 0.0068 0.1208 0.1208
Schistosoma mansoni amine GPCR 0.0068 0.1208 0.3613
Loa Loa (eye worm) hypothetical protein 0.001 0.0073 0.0219
Loa Loa (eye worm) hypothetical protein 0.0068 0.1208 0.3613
Loa Loa (eye worm) cyclin C 0.0014 0.0149 0.0445
Brugia malayi putative neuropeptide receptor NPR1 0.0068 0.1208 0.1208
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0015 0.0171 0.0447
Giardia lamblia Cyclin A 0.0057 0.0999 0.4887
Schistosoma mansoni amine GPCR 0.0068 0.1208 0.3613
Trypanosoma cruzi DNA polymerase eta, putative 0.002 0.0271 0.1323
Echinococcus multilocularis rhodopsin orphan GPCR 0.0068 0.1208 0.3571
Schistosoma mansoni cyclin G2 0.0014 0.0149 0.0445
Loa Loa (eye worm) hypothetical protein 0.0068 0.1208 0.3613
Schistosoma mansoni hypothetical protein 0.0015 0.0171 0.051
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0068 0.1208 0.3571
Loa Loa (eye worm) hypothetical protein 0.0054 0.0924 0.2764
Loa Loa (eye worm) hypothetical protein 0.001 0.0073 0.0219
Echinococcus multilocularis Cyclin L1 0.0014 0.0149 0.0382
Entamoeba histolytica cyclin, putative 0.0057 0.0999 0.4486
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0068 0.1208 0.3613
Echinococcus granulosus hyperpolarization activated cyclic 0.0008 0.0027 0.0013
Schistosoma mansoni cytochrome P450 0.0007 0.0022 0.0066
Loa Loa (eye worm) cytochrome P450 0.0007 0.0022 0.0066
Entamoeba histolytica cyclin family protein 0.0057 0.0999 0.4486
Onchocerca volvulus Protein CNPPD1 homolog 0.0014 0.0149 0.0384
Echinococcus granulosus G2:mitotic specific cyclin B3 0.0177 0.3342 1
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.0014 0.0149 0.0445
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0068 0.1208 0.3613
Brugia malayi Melatonin receptor type 1A 0.0068 0.1208 0.1208
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0271 0.1323
Trichomonas vaginalis cyclin B, putative 0.0111 0.2045 1
Schistosoma mansoni cyclins 0.0057 0.0999 0.299
Echinococcus multilocularis pyruvate kinase 0.0018 0.0226 0.0615
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0068 0.1208 0.1208
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.001 0.0073 0.0154
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0068 0.1208 0.3613
Echinococcus granulosus orexin receptor type 2 0.0068 0.1208 0.3571
Brugia malayi G-protein coupled receptor 0.0068 0.1208 0.1208
Echinococcus multilocularis rhodopsin orphan GPCR 0.0068 0.1208 0.3571
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0068 0.1208 0.3571
Trichomonas vaginalis cyclins, putative 0.0111 0.2045 1
Trypanosoma cruzi CYC2-like cyclin, putative 0.0111 0.2045 1
Entamoeba histolytica deoxycytidyl transferase, putative 0.002 0.0271 0.0642
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0008 0.0027 0.0013
Onchocerca volvulus 0.0068 0.1208 0.5753
Echinococcus granulosus cyclins 0.0014 0.0149 0.0382
Loa Loa (eye worm) hypothetical protein 0.0111 0.2045 0.6119
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0271 0.1323
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0271 0.0271
Schistosoma mansoni biogenic amine receptor 0.0068 0.1208 0.3613
Echinococcus multilocularis fmrfamide receptor 0.0068 0.1208 0.3571
Onchocerca volvulus Neuropeptide F receptor homolog 0.0068 0.1208 0.5753
Echinococcus multilocularis cyclin 0.0014 0.0149 0.0382
Echinococcus granulosus sex peptide receptor 0.0068 0.1208 0.3571
Loa Loa (eye worm) hypothetical protein 0.0068 0.1208 0.3613
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0271 0.1323
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0068 0.1208 0.3613
Loa Loa (eye worm) hypothetical protein 0.0068 0.1208 0.3613
Echinococcus granulosus 7TM GPCR rhodopsin 0.0068 0.1208 0.3571
Echinococcus multilocularis G-protein coupled receptor, putative 0.0068 0.1208 0.3571
Loa Loa (eye worm) hypothetical protein 0.0068 0.1208 0.3613
Trypanosoma cruzi mitotic cyclin, putative 0.0014 0.0149 0.0728
Schistosoma mansoni histamine h1 receptor 0.0068 0.1208 0.3613
Onchocerca volvulus 0.0068 0.1208 0.5753
Trypanosoma cruzi cyclin, putative 0.0111 0.2045 1
Echinococcus multilocularis cyclin y 0.0014 0.0149 0.0382
Schistosoma mansoni biogenic amine (5HT) receptor 0.0068 0.1208 0.3613
Loa Loa (eye worm) hypothetical protein 0.0068 0.1208 0.3613
Chlamydia trachomatis pyruvate kinase 0.0035 0.0556 0.5
Echinococcus granulosus cyclins 0.0057 0.0999 0.2944
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0008 0.0027 0.008
Loa Loa (eye worm) hypothetical protein 0.0068 0.1208 0.3613
Echinococcus multilocularis neuropeptide receptor 0.0068 0.1208 0.3571
Loa Loa (eye worm) melatonin receptor type 1A 0.0068 0.1208 0.3613
Entamoeba histolytica cell division protein kinase 2, putative 0.0047 0.0787 0.3364
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0073 0.0073
Echinococcus granulosus ecdysone induced protein 78C 0.001 0.0073 0.0154
Schistosoma mansoni neuropeptide F-like receptor 0.0068 0.1208 0.3613
Trypanosoma cruzi pyruvate kinase 2, putative 0.0035 0.0556 0.2721
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0008 0.0027 0.0013
Echinococcus granulosus pyruvate kinase 0.0018 0.0226 0.0615
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0007 0.0022 0.0108
Loa Loa (eye worm) CYP4Cod1 0.0007 0.0022 0.0066
Loa Loa (eye worm) hypothetical protein 0.0014 0.0149 0.0445
Schistosoma mansoni hypothetical protein 0.0068 0.1208 0.3613
Echinococcus multilocularis cyclin G2 0.0014 0.0149 0.0382
Schistosoma mansoni neuropeptide receptor 0.0068 0.1208 0.3613
Echinococcus multilocularis g-protein coupled receptor 0.0068 0.1208 0.3571
Loa Loa (eye worm) hypothetical protein 0.0068 0.1208 0.3613
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0073 0.0073
Brugia malayi Cyclin, N-terminal domain containing protein 0.0111 0.2045 0.2045
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0068 0.1208 0.3613
Onchocerca volvulus 0.0068 0.1208 0.5753
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0149 0.0605
Loa Loa (eye worm) cyclin domain-containing protein 0.0014 0.0149 0.0445
Trypanosoma cruzi cdc2-related kinase 3 0.0047 0.0787 0.3847
Echinococcus granulosus rhodopsin orphan GPCR 0.0068 0.1208 0.3571
Schistosoma mansoni nuclear hormone receptor 0.001 0.0073 0.0219
Echinococcus granulosus death domain containing protein 0.0015 0.0171 0.0447
Echinococcus multilocularis pyruvate kinase 0.0018 0.0226 0.0615
Echinococcus granulosus pyruvate kinase 0.0018 0.0226 0.0615
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0068 0.1208 0.3571
Brugia malayi Serotonin receptor 0.0068 0.1208 0.1208
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0149 0.0728
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0047 0.0787 0.2354
Onchocerca volvulus 0.0068 0.1208 0.5753
Entamoeba histolytica cyclin, putative 0.0111 0.2045 1
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.002 0.0271 0.1323
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0068 0.1208 0.3571
Loa Loa (eye worm) hypothetical protein 0.0068 0.1208 0.3613
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0068 0.1208 0.3613
Loa Loa (eye worm) cytochrome P450 family protein 0.0007 0.0022 0.0066
Echinococcus granulosus cyclin b3 0.0057 0.0999 0.2944
Schistosoma mansoni steroid hormone receptor ad4bp 0.001 0.0073 0.0219
Loa Loa (eye worm) pyruvate kinase 0.0007 0.0021 0.0063
Schistosoma mansoni hypothetical protein 0.0014 0.0149 0.0445
Schistosoma mansoni cyclin G 0.0014 0.0149 0.0445
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0073 0.0073
Echinococcus multilocularis rhodopsin orphan GPCR 0.0068 0.1208 0.3571
Loa Loa (eye worm) hypothetical protein 0.0068 0.1208 0.3613
Schistosoma mansoni growth hormone secretagogue receptor 0.0068 0.1208 0.3613
Loa Loa (eye worm) hypothetical protein 0.0068 0.1208 0.3613
Giardia lamblia Hypothetical protein 0.0057 0.0999 0.4887
Echinococcus granulosus g protein coupled receptor 0.0068 0.1208 0.3571
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0068 0.1208 0.3613
Brugia malayi Cyclin, N-terminal domain containing protein 0.0014 0.0149 0.0149
Trichomonas vaginalis cyclin B, putative 0.0111 0.2045 1
Trichomonas vaginalis cyclin B3, putative 0.0014 0.0149 0.0605
Loa Loa (eye worm) hypothetical protein 0.0068 0.1208 0.3613
Onchocerca volvulus Pyruvate kinase homolog 0.0035 0.0556 0.2451
Plasmodium vivax hypothetical protein, conserved 0.0014 0.0149 0.1891
Trypanosoma brucei cyclin dependent kinase-binding protein, putative 0.0014 0.0149 0.0728
Loa Loa (eye worm) hypothetical protein 0.0068 0.1208 0.3613
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.001 0.0073 0.0154
Brugia malayi hypothetical protein 0.0068 0.1208 0.1208
Echinococcus multilocularis G1:S specific cyclin D1 0.0014 0.0149 0.0382
Trypanosoma cruzi cyclin 6, putative 0.0111 0.2045 1
Loa Loa (eye worm) G-protein coupled receptor 0.0068 0.1208 0.3613
Echinococcus multilocularis serotonin receptor 0.0068 0.1208 0.3571
Echinococcus granulosus oligomeric golgi complex subunit 3 0.0014 0.0149 0.0382
Schistosoma mansoni Tr4/Tr2 (homologue) 0.001 0.0073 0.0219
Trichomonas vaginalis cyclin B3, putative 0.0014 0.0149 0.0605
Brugia malayi Nuclear hormone receptor family member nhr-41 0.001 0.0073 0.0073
Loa Loa (eye worm) hypothetical protein 0.0068 0.1208 0.3613
Echinococcus granulosus neuropeptide Y receptor 0.0068 0.1208 0.3571
Loa Loa (eye worm) hypothetical protein 0.0015 0.0173 0.0518
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0068 0.1208 0.3613
Loa Loa (eye worm) hypothetical protein 0.0068 0.1208 0.3613
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0007 0.0022 0.0398
Loa Loa (eye worm) cyclin domain-containing protein 0.0014 0.0149 0.0445
Echinococcus multilocularis cdk5 and abl1 enzyme substrate 1 0.0014 0.0149 0.0382
Brugia malayi Cyclin, N-terminal domain containing protein 0.0014 0.0149 0.0149
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0068 0.1208 0.3571
Brugia malayi hypothetical protein 0.0068 0.1208 0.1208
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0014 0.0149 0.1489
Echinococcus multilocularis pyruvate kinase 0.0027 0.0414 0.1179
Onchocerca volvulus 0.0068 0.1208 0.5753
Loa Loa (eye worm) cytochrome P450 family protein 0.0007 0.0022 0.0066
Echinococcus granulosus peptide allatostatin:somatostatin 0.0068 0.1208 0.3571
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0068 0.1208 0.3613
Onchocerca volvulus Netrin receptor homolog 0.0015 0.0171 0.0494
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.001 0.0073 0.0154
Echinococcus granulosus cyclin t1 0.0014 0.0149 0.0382
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0047 0.0787 0.3847
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0007 0.0022 0.0398
Echinococcus multilocularis neuropeptide s receptor 0.0068 0.1208 0.3571
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0038 0.0628 0.188
Brugia malayi pyruvate kinase 0.0007 0.0021 0.0021
Trypanosoma cruzi cytochrome P450, putative 0.0007 0.0022 0.0108
Brugia malayi follicle stimulating hormone receptor 0.0068 0.1208 0.1208
Onchocerca volvulus 0.0068 0.1208 0.5753
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0007 0.0022 0.0398
Loa Loa (eye worm) hypothetical protein 0.0068 0.1208 0.3613
Schistosoma mansoni opsin-like receptor 0.0068 0.1208 0.3613
Onchocerca volvulus 0.0068 0.1208 0.5753
Schistosoma mansoni myosin xvIII 0.0068 0.1208 0.3613
Loa Loa (eye worm) hypothetical protein 0.0014 0.0149 0.0445
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0068 0.1208 0.3613
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.001 0.0073 0.0154
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.001 0.0073 0.0219
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0149 0.0728
Loa Loa (eye worm) TYRA-2 protein 0.0068 0.1208 0.3613
Brugia malayi Death domain containing protein 0.0015 0.0171 0.0171
Echinococcus multilocularis cyclins 0.0057 0.0999 0.2944
Trypanosoma brucei mitotic cyclin 6 0.0111 0.2045 1
Echinococcus multilocularis fmrfamide receptor 0.0068 0.1208 0.3571
Echinococcus granulosus dro:myosuppressin receptor 0.0068 0.1208 0.3571
Trichomonas vaginalis cyclins, putative 0.0014 0.0149 0.0605
Echinococcus multilocularis cyclins 0.0057 0.0999 0.2944
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0271 0.1323
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0036 0.0579 0.2736
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0068 0.1208 0.3571
Schistosoma mansoni voltage-gated potassium channel 0.0042 0.0697 0.2086
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0068 0.1208 0.3613
Echinococcus granulosus neuropeptide receptor 0.0068 0.1208 0.3571
Loa Loa (eye worm) hypothetical protein 0.0068 0.1208 0.3613
Loa Loa (eye worm) hypothetical protein 0.0068 0.1208 0.3613
Onchocerca volvulus Pyruvate kinase homolog 0.0035 0.0556 0.2451
Schistosoma mansoni alpha-1 adrenergic receptor 0.0068 0.1208 0.3613
Schistosoma mansoni Cyclin fold protein 0.0014 0.0149 0.0445
Loa Loa (eye worm) CYL-1 protein 0.0014 0.0149 0.0445
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0271 0.4863
Schistosoma mansoni hypothetical protein 0.0068 0.1208 0.3613
Onchocerca volvulus 0.0068 0.1208 0.5753
Entamoeba histolytica cyclin family protein 0.0057 0.0999 0.4486
Schistosoma mansoni ankyrin 23/unc44 0.0015 0.0171 0.051
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0271 0.1323
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.001 0.0073 0.0154
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0068 0.1208 0.3571
Echinococcus multilocularis neuropeptides capa receptor 0.0068 0.1208 0.3571
Echinococcus multilocularis pyruvate kinase 0.0018 0.0226 0.0615
Echinococcus multilocularis cyclin k 0.0014 0.0149 0.0382
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0068 0.1208 0.3571
Echinococcus multilocularis g protein coupled receptor 0.0068 0.1208 0.3571
Trichomonas vaginalis cyclin B, putative 0.0014 0.0149 0.0605
Mycobacterium leprae Probable pyruvate kinase PykA 0.0035 0.0556 1
Echinococcus granulosus hypothetical protein 0.0068 0.1208 0.3571
Schistosoma mansoni amine GPCR 0.0068 0.1208 0.3613
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0271 0.1323
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0149 0.0605
Loa Loa (eye worm) neuropeptide F receptor 0.0068 0.1208 0.3613
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0015 0.0173 0.0518
Brugia malayi hypothetical protein 0.0068 0.1208 0.1208
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0008 0.0027 0.0013
Brugia malayi Nuclear hormone receptor family member nhr-3 0.001 0.0073 0.0073
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.001 0.0073 0.0219
Echinococcus multilocularis pyruvate kinase 0.0035 0.0556 0.1609
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0011 0.0095 0.0095
Schistosoma mansoni neuropeptide receptor 0.0068 0.1208 0.3613
Echinococcus multilocularis thyroid hormone receptor alpha 0.001 0.0073 0.0154
Loa Loa (eye worm) hypothetical protein 0.0068 0.1208 0.3613
Schistosoma mansoni biogenic amine (5HT) receptor 0.0068 0.1208 0.3613
Plasmodium vivax cyclin dependent kinase binding protein, putative 0.0014 0.0149 0.1891
Loa Loa (eye worm) pyruvate kinase 0.0035 0.0556 0.1665
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0007 0.0022 0.0398
Echinococcus granulosus pyruvate kinase 0.0035 0.0556 0.1609
Loa Loa (eye worm) cyclin fold protein 1 variant b 0.0014 0.0149 0.0445
Echinococcus multilocularis hyperpolarization activated cyclic 0.0008 0.0027 0.0013
Loa Loa (eye worm) hypothetical protein 0.0068 0.1208 0.3613
Schistosoma mansoni hypothetical protein 0.0014 0.0149 0.0445
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0038 0.0628 0.1826
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0011 0.0095 0.0221
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0271 0.1323
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0047 0.0787 0.3847
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0036 0.0579 0.2736
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0007 0.0022 0.0108
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.001 0.0073 0.0219
Toxoplasma gondii cyclin dependent kinase binding protein 0.0014 0.0149 0.1891
Schistosoma mansoni neuropeptide f receptor 76f 0.0068 0.1208 0.3613
Echinococcus granulosus tachykinin peptides receptor 99D 0.0068 0.1208 0.3571
Leishmania major cyclin 0.0111 0.2045 1
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0068 0.1208 0.3613
Echinococcus granulosus dna polymerase kappa 0.002 0.0271 0.0748
Echinococcus granulosus g-protein coupled receptor 0.0068 0.1208 0.3571
Brugia malayi sulfakinin receptor protein 0.0068 0.1208 0.1208
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0068 0.1208 0.3613
Echinococcus multilocularis rhodopsin orphan GPCR 0.0068 0.1208 0.3571
Entamoeba histolytica cell division protein kinase 2, putative 0.0047 0.0787 0.3364
Trichomonas vaginalis cyclin B, putative 0.0111 0.2045 1
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0047 0.0787 1
Schistosoma mansoni netrin receptor unc5 0.0015 0.0171 0.051
Trichomonas vaginalis cyclin B3, putative 0.0057 0.0999 0.482
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0007 0.0022 0.0108
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0015 0.0171 0.051
Echinococcus granulosus netrin receptor unc 5 0.0015 0.0171 0.0447
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0068 0.1208 0.3613
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0068 0.1208 0.3613
Brugia malayi pyruvate kinase, muscle isozyme 0.0007 0.0021 0.0021
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0068 0.1208 0.3613
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0068 0.1208 0.3571
Plasmodium falciparum cyclin dependent kinase binding protein, putative 0.0014 0.0149 0.1489
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0068 0.1208 0.3571
Echinococcus granulosus G protein coupled receptor 139 0.0068 0.1208 0.3571
Echinococcus multilocularis cyclin dependent kinase 0.0047 0.0787 0.2303
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.002 0.0271 0.0748
Loa Loa (eye worm) hypothetical protein 0.0068 0.1208 0.3613
Onchocerca volvulus 0.0068 0.1208 0.5753
Plasmodium falciparum pyruvate kinase 0.0035 0.0556 0.5568
Leishmania major DNA polymerase eta, putative 0.002 0.0271 0.1323
Leishmania major mitotic cyclin, putative 0.0014 0.0149 0.0728
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0068 0.1208 0.1208
Echinococcus granulosus cyclin 0.0014 0.0149 0.0382
Brugia malayi GnHR receptor homolog 0.0068 0.1208 0.1208
Echinococcus multilocularis cyclin B3 1 0.0057 0.0999 0.2944
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0008 0.0027 0.0013
Loa Loa (eye worm) hypothetical protein 0.0068 0.1208 0.3613
Schistosoma mansoni pyruvate kinase 0.0018 0.0226 0.0677
Echinococcus multilocularis pyruvate kinase 0.0035 0.0556 0.1609
Brugia malayi Tachykinin-like peptides receptor 99D 0.0068 0.1208 0.1208
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0271 0.1323
Schistosoma mansoni voltage-gated potassium channel 0.0008 0.0027 0.008
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0007 0.0022 0.0398
Onchocerca volvulus 0.0068 0.1208 0.5753
Leishmania major cytochrome p450-like protein 0.0007 0.0022 0.0108
Trypanosoma brucei cyclin 9 0.0014 0.0149 0.0728
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0068 0.1208 0.3571
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0007 0.0022 0.0398
Loa Loa (eye worm) hypothetical protein 0.001 0.0073 0.0219
Brugia malayi Protein kinase domain containing protein 0.0015 0.018 0.018
Loa Loa (eye worm) hypothetical protein 0.0068 0.1208 0.3613
Trichomonas vaginalis DNA polymerase eta, putative 0.002 0.0271 0.1209
Echinococcus granulosus cyclins 0.0057 0.0999 0.2944
Brugia malayi nuclear receptor NHR-88 0.001 0.0073 0.0073
Schistosoma mansoni biogenic amine receptor 0.0068 0.1208 0.3613
Brugia malayi putative neuropeptide receptor 0.0068 0.1208 0.1208
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0271 0.1323
Echinococcus granulosus cyclin dependent kinase 0.0047 0.0787 0.2303
Schistosoma mansoni thyroid hormone receptor 0.001 0.0073 0.0219
Trypanosoma brucei mitotic cyclin 0.0014 0.0149 0.0728
Plasmodium vivax protein kinase Crk2 0.0047 0.0787 1
Loa Loa (eye worm) cyclin domain-containing protein 0.0014 0.0149 0.0445
Schistosoma mansoni retinoic acid receptor RXR 0.001 0.0073 0.0219
Schistosoma mansoni hypothetical protein 0.0068 0.1208 0.3613
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0271 0.4863
Trichomonas vaginalis CMGC family protein kinase 0.0047 0.0787 0.3766
Brugia malayi Nuclear hormone receptor family member nhr-49 0.001 0.0073 0.0073
Loa Loa (eye worm) hypothetical protein 0.0068 0.1208 0.3613
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.002 0.0271 0.081
Schistosoma mansoni RAR-like nuclear receptor 0.001 0.0073 0.0219
Schistosoma mansoni cyclin k 0.0014 0.0149 0.0445
Echinococcus granulosus cyclin k 0.0014 0.0149 0.0382
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0007 0.0022 0.0108
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0007 0.0022 0.0398
Plasmodium falciparum cyclin 1 0.0014 0.0149 0.1489
Echinococcus multilocularis Ankyrin 0.0015 0.0173 0.0454
Echinococcus multilocularis cyclin dependent kinase 5 0.0047 0.0787 0.2303
Echinococcus granulosus cyclin A3 4 0.0014 0.0149 0.0382
Loa Loa (eye worm) hypothetical protein 0.0068 0.1208 0.3613
Echinococcus granulosus Cyclin L1 0.0014 0.0149 0.0382
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0007 0.0022 0.0398
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0047 0.0787 0.2303
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0008 0.0027 0.008
Loa Loa (eye worm) hypothetical protein 0.0068 0.1208 0.3613
Trypanosoma cruzi cytochrome P450, putative 0.0007 0.0022 0.0108
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0068 0.1208 0.3571
Brugia malayi cytochrome P450 0.0007 0.0022 0.0022
Echinococcus multilocularis cyclins 0.0057 0.0999 0.2944
Trypanosoma brucei unspecified product 0.0014 0.0149 0.0728
Trichomonas vaginalis cyclin A, putative 0.0111 0.2045 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0073 0.0219
Echinococcus multilocularis ecdysone induced protein 78C 0.001 0.0073 0.0154
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0068 0.1208 0.3571
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0011 0.0095 0.0221
Brugia malayi Nuclear hormone receptor family member nhr-14 0.001 0.0073 0.0073
Echinococcus multilocularis neuropeptide Y receptor 0.0068 0.1208 0.3571
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0149 0.0728
Echinococcus multilocularis g protein coupled receptor 0.0068 0.1208 0.3571
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.001 0.0073 0.0154
Onchocerca volvulus Cyclin L homolog 0.0014 0.0149 0.0384
Trypanosoma cruzi pyruvate kinase 2, putative 0.0035 0.0556 0.2721
Echinococcus granulosus somatostatin receptor 0.0068 0.1208 0.3571
Loa Loa (eye worm) hypothetical protein 0.001 0.0073 0.0219
Echinococcus granulosus pyruvate kinase 0.0018 0.0226 0.0615
Trypanosoma cruzi cdc2-related kinase 1 0.0047 0.0787 0.3847
Brugia malayi Immunoglobulin I-set domain containing protein 0.0015 0.0171 0.0171
Loa Loa (eye worm) hypothetical protein 0.002 0.0271 0.081
Brugia malayi Cyclin, N-terminal domain containing protein 0.0014 0.0149 0.0149
Echinococcus multilocularis cyclins 0.0057 0.0999 0.2944
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.002 0.0271 0.0748
Trichomonas vaginalis cyclin D, putative 0.0014 0.0149 0.0605
Giardia lamblia Hypothetical protein 0.0014 0.0149 0.0728
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0007 0.0022 0.0398
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0073 0.0154
Echinococcus multilocularis cyclins 0.0057 0.0999 0.2944
Loa Loa (eye worm) pyruvate kinase 0.0035 0.0556 0.1665
Schistosoma mansoni voltage-gated potassium channel 0.0011 0.0095 0.0286
Brugia malayi hypothetical protein 0.0068 0.1208 0.1208
Echinococcus granulosus cyclin dependent kinase 5 0.0047 0.0787 0.2303
Toxoplasma gondii hypothetical protein 0.0014 0.0149 0.1891
Entamoeba histolytica pyruvate kinase, putative 0.0024 0.0351 0.1068
Schistosoma mansoni cyclin l 0.0014 0.0149 0.0445
Echinococcus multilocularis voltage gated potassium channel 0.0011 0.0095 0.0221
Echinococcus multilocularis cyclin dependent kinase 1 0.0047 0.0787 0.2303
Loa Loa (eye worm) hypothetical protein 0.0068 0.1208 0.3613
Echinococcus granulosus cyclins 0.0057 0.0999 0.2944
Brugia malayi Cyclin, N-terminal domain containing protein 0.0014 0.0149 0.0149
Toxoplasma gondii pyruvate kinase PyKII 0.0018 0.0226 0.2877
Leishmania major cyclin 9, putative 0.0014 0.0149 0.0728
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0007 0.0022 0.0398
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0008 0.0027 0.008
Echinococcus granulosus rhodopsin orphan GPCR 0.0068 0.1208 0.3571
Loa Loa (eye worm) hypothetical protein 0.0046 0.0777 0.2325
Echinococcus multilocularis rhodopsin orphan GPCR 0.0068 0.1208 0.3571
Echinococcus granulosus FTZ F1 alpha 0.001 0.0073 0.0154
Toxoplasma gondii cytochrome p450 superfamily protein 0.0007 0.0022 0.0281
Loa Loa (eye worm) hypothetical protein 0.0011 0.0095 0.0286
Brugia malayi ORL1-like opioid receptor 0.0068 0.1208 0.1208
Brugia malayi cyclin fold protein 1 variant b 0.0014 0.0149 0.0149
Giardia lamblia Kinase, CMGC CDK 0.0047 0.0787 0.3847
Brugia malayi neuropeptide F receptor 0.0068 0.1208 0.1208
Echinococcus granulosus serotonin receptor 0.0068 0.1208 0.3571
Loa Loa (eye worm) G-protein coupled receptor 0.0068 0.1208 0.3613
Echinococcus multilocularis cyclin t1 0.0014 0.0149 0.0382
Giardia lamblia Cyclin fold protein 1, putative 0.0014 0.0149 0.0728
Plasmodium vivax cyclin 4, putative 0.0014 0.0149 0.1891
Echinococcus granulosus rhodopsin orphan GPCR 0.0068 0.1208 0.3571
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.001 0.0073 0.0219
Echinococcus granulosus rhodopsin orphan GPCR 0.0068 0.1208 0.3571
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0271 0.1323
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0007 0.0022 0.0398
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.002 0.0271 0.465
Brugia malayi Cyclin, N-terminal domain containing protein 0.0177 0.3342 0.3342
Trichomonas vaginalis pyruvate kinase, putative 0.0035 0.0556 0.2625
Echinococcus granulosus tm gpcr rhodopsin 0.0068 0.1208 0.3571
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0073 0.0073
Echinococcus granulosus neuropeptide s receptor 0.0068 0.1208 0.3571
Giardia lamblia G2/mitotic-specific cyclin B 0.0111 0.2045 1
Loa Loa (eye worm) hypothetical protein 0.0068 0.1208 0.3613
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0149 0.0605
Echinococcus granulosus cyclins 0.0057 0.0999 0.2944
Giardia lamblia Pyruvate kinase 0.0018 0.0226 0.1107
Brugia malayi Nuclear hormone receptor family member nhr-40 0.001 0.0073 0.0073
Trypanosoma brucei cdc2-related kinase 3 0.0047 0.0787 0.3847
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0008 0.0027 0.008
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.001 0.0073 0.0219
Onchocerca volvulus Cyclin L homolog 0.0014 0.0149 0.0384
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0068 0.1208 0.1208
Loa Loa (eye worm) hypothetical protein 0.001 0.0073 0.0219
Echinococcus multilocularis dro:myosuppressin receptor 0.0068 0.1208 0.3571
Brugia malayi hypothetical protein 0.0068 0.1208 0.1208
Schistosoma mansoni opsin-like receptor 0.0068 0.1208 0.3613
Trypanosoma cruzi cyclin 9, putative 0.0014 0.0149 0.0728
Echinococcus multilocularis allatostatin A receptor 0.0068 0.1208 0.3571
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0068 0.1208 0.3613
Echinococcus granulosus cyclin y 0.0014 0.0149 0.0382
Brugia malayi hypothetical protein 0.0014 0.0149 0.0149
Trypanosoma cruzi cdc2-related kinase 3 0.0047 0.0787 0.3847
Loa Loa (eye worm) hypothetical protein 0.0068 0.1208 0.3613
Trichomonas vaginalis cyclins, putative 0.0067 0.1194 0.5786
Brugia malayi hypothetical protein 0.0068 0.1208 0.1208
Brugia malayi Cyclin, N-terminal domain containing protein 0.0014 0.0149 0.0149
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0007 0.0022 0.0398
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0008 0.0027 0.0013
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0068 0.1208 0.3571
Loa Loa (eye worm) cyclin domain-containing protein 0.0014 0.0149 0.0445
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0068 0.1208 0.3613
Echinococcus granulosus cyclin G2 0.0014 0.0149 0.0382
Brugia malayi Dopamine receptor protein 2 0.0068 0.1208 0.1208
Echinococcus granulosus neuropeptide Y receptor 0.0068 0.1208 0.3571
Loa Loa (eye worm) pyruvate kinase 0.0035 0.0556 0.1665
Echinococcus multilocularis neuropeptides capa receptor 0.0068 0.1208 0.3571
Brugia malayi Pyruvate kinase, M2 isozyme 0.0035 0.0556 0.0556
Echinococcus granulosus cyclins 0.0057 0.0999 0.2944
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0149 0.0728
Onchocerca volvulus 0.0068 0.1208 0.5753
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0271 0.1323
Echinococcus granulosus neuropeptide receptor 0.0068 0.1208 0.3571
Brugia malayi G protein-coupled receptor F59B2.13 0.0068 0.1208 0.1208
Echinococcus multilocularis neuropeptide receptor 0.0068 0.1208 0.3571
Brugia malayi hypothetical protein 0.0068 0.1208 0.1208
Brugia malayi Cyclin, N-terminal domain containing protein 0.0111 0.2045 0.2045
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0149 0.0605
Echinococcus multilocularis rhodopsin orphan GPCR 0.0068 0.1208 0.3571
Echinococcus granulosus Ankyrin 0.0015 0.0173 0.0454
Echinococcus multilocularis G protein coupled receptor 139 0.0068 0.1208 0.3571
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.001 0.0073 0.0219
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.002 0.0271 0.1209
Trichomonas vaginalis cyclin B, putative 0.0014 0.0149 0.0605
Plasmodium falciparum protein kinase 5 0.0047 0.0787 0.7873
Echinococcus multilocularis cyclin B 0.0111 0.2045 0.6093
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0073 0.0073
Echinococcus granulosus neuropeptide receptor A26 0.0068 0.1208 0.3571
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0271 0.465
Echinococcus granulosus cyclin G2 0.0014 0.0149 0.0382
Trichomonas vaginalis cyclins, putative 0.0111 0.2045 1
Trichomonas vaginalis cyclin D, putative 0.0057 0.0999 0.482
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0038 0.0628 0.0628
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.001 0.0073 0.0154
Loa Loa (eye worm) hypothetical protein 0.001 0.0073 0.0219
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0047 0.0787 0.2354
Leishmania major pyruvate kinase 0.0035 0.0556 0.2721
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0068 0.1208 0.3613
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0073 0.0154
Brugia malayi ecdysteroid receptor 0.001 0.0073 0.0073
Echinococcus multilocularis cyclin A3 4 0.0014 0.0149 0.0382
Loa Loa (eye worm) hypothetical protein 0.0068 0.1208 0.3613
Loa Loa (eye worm) hypothetical protein 0.0035 0.0556 0.1665
Loa Loa (eye worm) hypothetical protein 0.0068 0.1208 0.3613
Loa Loa (eye worm) hypothetical protein 0.0068 0.1208 0.3613
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0007 0.0022 0.0398
Schistosoma mansoni neuropeptide receptor 0.0068 0.1208 0.3613
Mycobacterium ulcerans pyruvate kinase 0.0035 0.0556 1
Leishmania major cytochrome p450-like protein 0.0007 0.0022 0.0108
Plasmodium vivax pyruvate kinase 2, putative 0.0018 0.0226 0.2877
Loa Loa (eye worm) hypothetical protein 0.0024 0.0351 0.1051
Loa Loa (eye worm) hypothetical protein 0.0068 0.1208 0.3613
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0007 0.0022 0.0398
Loa Loa (eye worm) hypothetical protein 0.0068 0.1208 0.3613
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.001 0.0073 0.0219
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0999 0.482
Giardia lamblia Kinase, CMGC CDK 0.0047 0.0787 0.3847
Echinococcus granulosus voltage gated potassium channel 0.0011 0.0095 0.0221
Schistosoma mansoni retinoid-x-receptor (RXR) 0.001 0.0073 0.0219
Trypanosoma brucei unspecified product 0.002 0.0271 0.1323
Plasmodium vivax cyclin homologue, putative 0.0014 0.0149 0.1891
Schistosoma mansoni cyclin B 0.0111 0.2045 0.6119
Leishmania major cytochrome p450-like protein 0.0007 0.0022 0.0108
Onchocerca volvulus 0.0068 0.1208 0.5753
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0068 0.1208 0.3571
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0047 0.0787 0.2354
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0068 0.1208 0.3571
Brugia malayi G-protein coupled receptor 0.0068 0.1208 0.1208
Trypanosoma cruzi cdc2-related kinase 1 0.0047 0.0787 0.3847
Brugia malayi Nuclear hormone receptor family member nhr-1 0.001 0.0073 0.0073
Brugia malayi hypothetical protein 0.0068 0.1208 0.1208
Loa Loa (eye worm) hypothetical protein 0.0068 0.1208 0.3613
Trypanosoma brucei pyruvate kinase 1, putative 0.0035 0.0556 0.2721
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0068 0.1208 0.3613
Schistosoma mansoni thyroid hormone receptor 0.001 0.0073 0.0219
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0073 0.0154
Echinococcus multilocularis cyclin dependent kinase 1 0.0047 0.0787 0.2303
Loa Loa (eye worm) hypothetical protein 0.001 0.0073 0.0219
Echinococcus multilocularis cyclins 0.0057 0.0999 0.2944
Echinococcus granulosus fmrfamide receptor 0.0068 0.1208 0.3571
Trypanosoma cruzi cyclin, putative 0.0111 0.2045 1
Brugia malayi neuropeptide F receptor 0.0068 0.1208 0.1208
Schistosoma mansoni neuropeptide receptor 0.0068 0.1208 0.3613
Brugia malayi Cyclin, N-terminal domain containing protein 0.0014 0.0149 0.0149
Echinococcus granulosus dna polymerase eta 0.002 0.0271 0.0748
Echinococcus granulosus tm gpcr rhodopsin 0.0068 0.1208 0.3571
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0073 0.0154
Trichomonas vaginalis cyclins, putative 0.0014 0.0149 0.0605
Echinococcus granulosus nuclear factor of activated T cells 5 0.0077 0.1375 0.4076
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.0111 0.2045 1
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0068 0.1208 0.3571
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0008 0.0027 0.008
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0271 0.1323
Echinococcus granulosus g protein coupled receptor 0.0068 0.1208 0.3571
Schistosoma mansoni opsin-like receptor 0.0068 0.1208 0.3613
Loa Loa (eye worm) cytochrome P450 family protein 0.0007 0.0022 0.0066
Brugia malayi Dopamine receptor 0.0068 0.1208 0.1208
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0007 0.0022 0.0398
Schistosoma mansoni pyruvate kinase 0.0035 0.0556 0.1665
Onchocerca volvulus 0.0014 0.0149 0.0384
Brugia malayi G protein-coupled receptor 0.0068 0.1208 0.1208
Echinococcus multilocularis neuropeptide receptor A26 0.0068 0.1208 0.3571
Echinococcus granulosus hyperpolarization activated cyclic 0.0008 0.0027 0.0013
Echinococcus multilocularis rhodopsin orphan GPCR 0.0068 0.1208 0.3571
Echinococcus granulosus allatostatin A receptor 0.0068 0.1208 0.3571
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0068 0.1208 0.3571
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0007 0.0022 0.0398
Echinococcus granulosus neuropeptide FF receptor 2 0.0068 0.1208 0.3571
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0068 0.1208 0.3613
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.001 0.0073 0.0219
Echinococcus multilocularis hyperpolarization activated cyclic 0.0008 0.0027 0.0013
Schistosoma mansoni neuropeptide F-like receptor 0.0068 0.1208 0.3613
Loa Loa (eye worm) hypothetical protein 0.0068 0.1208 0.3613
Echinococcus granulosus 7tm_1 domain containing protein 0.0068 0.1208 0.3571
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0007 0.0022 0.0398
Echinococcus multilocularis somatostatin receptor 0.0068 0.1208 0.3571
Loa Loa (eye worm) hypothetical protein 0.0068 0.1208 0.3613
Loa Loa (eye worm) hypothetical protein 0.0068 0.1208 0.3613
Trypanosoma brucei cdc2-related kinase 1 0.0047 0.0787 0.3847
Loa Loa (eye worm) hypothetical protein 0.0068 0.1208 0.3613
Brugia malayi Cyclin, N-terminal domain containing protein 0.0014 0.0149 0.0149
Plasmodium falciparum cyclin 0.0057 0.0999 1
Brugia malayi Dopamine receptor protein 1 0.0068 0.1208 0.1208
Echinococcus multilocularis sex peptide receptor 0.0068 0.1208 0.3571
Echinococcus granulosus cyclin y 0.0014 0.0149 0.0382
Toxoplasma gondii hypothetical protein 0.0044 0.0729 0.9264
Echinococcus granulosus cdk5 and abl1 enzyme substrate 1 0.0014 0.0149 0.0382
Echinococcus multilocularis serotonin receptor 0.0068 0.1208 0.3571
Echinococcus granulosus rhodopsin orphan GPCR 0.0068 0.1208 0.3571
Loa Loa (eye worm) hypothetical protein 0.0033 0.0529 0.1583
Trichomonas vaginalis cyclin A, putative 0.0014 0.0149 0.0605
Loa Loa (eye worm) hypothetical protein 0.0015 0.0171 0.051
Echinococcus multilocularis neuropeptide FF receptor 2 0.0068 0.1208 0.3571
Echinococcus granulosus G1:S specific cyclin D1 0.0014 0.0149 0.0382
Schistosoma mansoni serine/threonine protein kinase 0.0047 0.0787 0.2354
Onchocerca volvulus 0.0111 0.2045 1
Brugia malayi Cyclic-nucleotide gated cation channel 0.0008 0.0027 0.0027
Echinococcus multilocularis oligomeric golgi complex subunit 3 0.0014 0.0149 0.0382
Schistosoma mansoni adenoreceptor 0.0068 0.1208 0.3613
Echinococcus multilocularis FTZ F1 alpha 0.001 0.0073 0.0154
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0007 0.0022 0.0398
Trichomonas vaginalis cyclins, putative 0.0111 0.2045 1
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0008 0.0027 0.008
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0073 0.0073
Echinococcus granulosus rhodopsin orphan GPCR 0.0068 0.1208 0.3571
Trypanosoma brucei unspecified product 0.0014 0.0149 0.0728
Schistosoma mansoni hypothetical protein 0.0007 0.0022 0.0066
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0068 0.1208 0.3613
Loa Loa (eye worm) hypothetical protein 0.0068 0.1208 0.3613
Echinococcus granulosus cyclin dependent kinase 1 0.0047 0.0787 0.2303
Brugia malayi hypothetical protein 0.0068 0.1208 0.1208
Echinococcus granulosus neuropeptides capa receptor 0.0068 0.1208 0.3571
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.001 0.0073 0.0219
Loa Loa (eye worm) pyruvate kinase-PB 0.0024 0.0351 0.1051
Leishmania major mitotic cyclin, putative 0.0014 0.0149 0.0728
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0008 0.0027 0.008
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0271 0.0271
Echinococcus multilocularis g protein coupled receptor 0.0068 0.1208 0.3571
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0007 0.0022 0.0398
Toxoplasma gondii cyclin, N-terminal domain-containing protein 0.0014 0.0149 0.1891
Echinococcus granulosus retinoic acid receptor rxr beta a 0.001 0.0073 0.0154
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0068 0.1208 0.1208
Giardia lamblia Cyclin B-like protein 0.0014 0.0149 0.0728
Brugia malayi Pyruvate kinase, alpha/beta domain containing protein 0.0011 0.0083 0.0083
Trichomonas vaginalis cyclins, putative 0.0057 0.0999 0.482
Echinococcus multilocularis G2:mitotic specific cyclin B3 0.0177 0.3342 1
Brugia malayi Protein kinase domain containing protein 0.0047 0.0787 0.0787
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.001 0.0073 0.0154
Echinococcus multilocularis neuropeptide Y receptor 0.0068 0.1208 0.3571
Loa Loa (eye worm) cyclin domain-containing protein 0.0177 0.3342 1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.