Detailed information for compound 1297071

Basic information

Technical information
  • TDR Targets ID: 1297071
  • Name: 4-ethoxy-N-(1-phenylsulfonylpiperidin-4-yl)be nzamide
  • MW: 388.481 | Formula: C20H24N2O4S
  • H donors: 1 H acceptors: 3 LogP: 2.94 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOc1ccc(cc1)C(=O)NC1CCN(CC1)S(=O)(=O)c1ccccc1
  • InChi: 1S/C20H24N2O4S/c1-2-26-18-10-8-16(9-11-18)20(23)21-17-12-14-22(15-13-17)27(24,25)19-6-4-3-5-7-19/h3-11,17H,2,12-15H2,1H3,(H,21,23)
  • InChiKey: KDAKLOSUTNSSPK-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 4-ethoxy-N-(1-phenylsulfonyl-4-piperidyl)benzamide
  • 4-ethoxy-N-(1-phenylsulfonyl-4-piperidinyl)benzamide

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens geminin, DNA replication inhibitor Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi Hypothetical 65.5 kDa Trp-Asp repeats containing protein F02E8.5 inchromosome X geminin, DNA replication inhibitor 209 aa 176 aa 27.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni transcription factor LCR-F1 0.0073 0.072 0.3036
Toxoplasma gondii hypothetical protein 0.0055 0.0496 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0716 0.1748
Schistosoma mansoni hypothetical protein 0.0205 0.2309 1
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0073 0.072 0.0804
Schistosoma mansoni hypothetical protein 0.0035 0.0257 0.1006
Echinococcus multilocularis musashi 0.0026 0.0148 0.012
Echinococcus multilocularis lysine specific demethylase 5A 0.0037 0.0272 0.0245
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0048 0.0411 0.0973
Brugia malayi latrophilin 2 splice variant baaae 0.0035 0.0257 0.0615
Mycobacterium ulcerans hypothetical protein 0.018 0.2007 0.5
Onchocerca volvulus 0.0271 0.3119 1
Schistosoma mansoni intermediate filament proteins 0.0026 0.0148 0.0526
Schistosoma mansoni bromodomain containing protein 0.0127 0.1374 0.5901
Brugia malayi Bromodomain containing protein 0.0151 0.166 0.3969
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0019 0.0062 0.0035
Loa Loa (eye worm) MH2 domain-containing protein 0.0359 0.4183 1
Brugia malayi Pre-SET motif family protein 0.0034 0.0244 0.0584
Loa Loa (eye worm) hypothetical protein 0.0016 0.0028 0.0066
Trypanosoma cruzi cysteine peptidase, putative 0.0073 0.0716 0.1748
Plasmodium vivax SET domain protein, putative 0.0034 0.0244 1
Leishmania major cathepsin L-like protease 0.0073 0.0716 0.1748
Echinococcus granulosus histone lysine methyltransferase setb 0.0069 0.066 0.0735
Loa Loa (eye worm) hypothetical protein 0.0069 0.066 0.1579
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0341 0.3963 1
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.003 0.0195 0.0736
Echinococcus multilocularis geminin 0.0205 0.2309 0.2288
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0028 0.0066
Echinococcus granulosus lamin 0.0026 0.0148 0.0139
Leishmania major cathepsin L-like protease 0.0019 0.0062 0.0087
Schistosoma mansoni lamin 0.0026 0.0148 0.0526
Loa Loa (eye worm) fibroinase 0.0019 0.0062 0.0149
Leishmania major cysteine peptidase A (CPA) 0.0019 0.0062 0.0087
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0161 0.1786 0.4467
Brugia malayi RNA binding protein 0.0064 0.0608 0.1453
Onchocerca volvulus 0.0034 0.0244 0.0595
Brugia malayi Calcitonin receptor-like protein seb-1 0.0052 0.0455 0.1088
Trypanosoma brucei ISWI complex protein 0.0031 0.0203 0.0445
Loa Loa (eye worm) hypothetical protein 0.0142 0.1556 0.3719
Loa Loa (eye worm) TAR-binding protein 0.0064 0.0608 0.1453
Schistosoma mansoni jumonji/arid domain-containing protein 0.004 0.0319 0.1277
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0608 0.2542
Echinococcus granulosus mothers against decapentaplegic 5 0.0024 0.0126 0.0115
Echinococcus granulosus PHD finger protein rhinoceros 0.003 0.0195 0.0195
Echinococcus granulosus TGF beta signal transducer SmadC 0.0024 0.0126 0.0115
Schistosoma mansoni methyl-cpg binding protein mbd 0.0034 0.0246 0.0957
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0716 0.1748
Echinococcus granulosus lamin dm0 0.0026 0.0148 0.0139
Brugia malayi RNA recognition motif domain containing protein 0.0064 0.0608 0.1453
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0072 0.0707 0.0788
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0048 0.0411 0.0973
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0341 0.3963 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0716 0.1748
Echinococcus granulosus Smad4 0.0024 0.0126 0.0115
Schistosoma mansoni cathepsin F (C01 family) 0.0019 0.0062 0.0152
Echinococcus granulosus tumor protein p63 0.0727 0.8641 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.0257 0.0615
Schistosoma mansoni smad1 5 8 and 0.0024 0.0126 0.0433
Loa Loa (eye worm) hypothetical protein 0.003 0.0195 0.0467
Leishmania major hypothetical protein, conserved 0.0031 0.0203 0.0445
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0161 0.1786 0.4467
Loa Loa (eye worm) hypothetical protein 0.0077 0.0766 0.1832
Onchocerca volvulus 0.0026 0.0148 0.0279
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0028 0.0066
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0716 0.1748
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0073 0.072 0.0695
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0048 0.0411 0.0973
Brugia malayi Cathepsin L-like precursor 0.0019 0.0062 0.0149
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0033 0.0229 0.0234
Echinococcus granulosus intermediate filament protein 0.0026 0.0148 0.0139
Loa Loa (eye worm) hypothetical protein 0.0086 0.0871 0.2081
Schistosoma mansoni cathepsin F (C01 family) 0.0019 0.0062 0.0152
Loa Loa (eye worm) jmjC domain-containing protein 0.004 0.0319 0.0763
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0238 0.2719 0.6501
Loa Loa (eye worm) MH1 domain-containing protein 0.0024 0.0126 0.0302
Brugia malayi Cathepsin L-like precursor 0.0019 0.0062 0.0149
Echinococcus multilocularis cysteine protease 0.0019 0.0062 0.0035
Echinococcus granulosus zinc finger protein 0.0039 0.0307 0.0325
Trypanosoma cruzi major cysteine proteinase, putative 0.0057 0.0526 0.1266
Brugia malayi Cathepsin L-like precursor 0.0019 0.0062 0.0149
Entamoeba histolytica hypothetical protein 0.0073 0.072 1
Echinococcus multilocularis cathepsin L cysteine protease 0.0019 0.0062 0.0035
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0034 0.0244 0.4618
Onchocerca volvulus 0.0026 0.0148 0.0279
Brugia malayi Cathepsin L-like precursor 0.0019 0.0062 0.0149
Schistosoma mansoni hypothetical protein 0.003 0.0195 0.0736
Echinococcus granulosus cathepsin l cysteine peptidase 0.0019 0.0062 0.004
Giardia lamblia PHD finger protein 15 0.003 0.0195 0.5
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0099 0.1027 0.1161
Trypanosoma cruzi cysteine peptidase, putative 0.0073 0.0716 0.1748
Loa Loa (eye worm) transcription factor SMAD2 0.0359 0.4183 1
Echinococcus multilocularis mothers against decapentaplegic 5 0.0024 0.0126 0.0099
Loa Loa (eye worm) hypothetical protein 0.0019 0.0062 0.0149
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.012 0.1287 0.1263
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0069 0.066 0.2774
Brugia malayi Bromodomain containing protein 0.0077 0.0764 0.1827
Brugia malayi MH2 domain containing protein 0.0359 0.4183 1
Schistosoma mansoni hypothetical protein 0.0205 0.2309 1
Entamoeba histolytica hypothetical protein 0.0073 0.072 1
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0148 0.0353
Schistosoma mansoni smad1 5 8 and 0.0024 0.0126 0.0433
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0045 0.038 0.0353
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0716 0.1748
Schistosoma mansoni smad1 5 8 and 0.0024 0.0126 0.0433
Mycobacterium tuberculosis Conserved hypothetical protein 0.018 0.2007 1
Brugia malayi MH1 domain containing protein 0.0024 0.0126 0.0302
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0024 0.0126 0.0099
Trichomonas vaginalis set domain proteins, putative 0.0271 0.3119 1
Brugia malayi intermediate filament protein 0.0026 0.0148 0.0353
Loa Loa (eye worm) PHD-finger family protein 0.0042 0.0333 0.0797
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0716 0.1748
Brugia malayi Papain family cysteine protease containing protein 0.0019 0.0062 0.0149
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0028 0.0067
Schistosoma mansoni hypothetical protein 0.0042 0.0333 0.134
Brugia malayi TAR-binding protein 0.0064 0.0608 0.1453
Loa Loa (eye worm) Smad1 0.0024 0.0126 0.0302
Echinococcus multilocularis peregrin 0.0035 0.0253 0.0226
Echinococcus multilocularis lamin 0.0026 0.0148 0.012
Onchocerca volvulus 0.0106 0.112 0.3459
Trypanosoma cruzi cysteine peptidase, putative 0.0019 0.0062 0.0087
Schistosoma mansoni zinc finger protein 0.0031 0.0203 0.0769
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0148 0.0353
Echinococcus multilocularis cathepsin L cysteine protease 0.0019 0.0062 0.0035
Trypanosoma cruzi cruzipain precursor, putative 0.0073 0.0716 0.1748
Leishmania major cathepsin L-like protease 0.0019 0.0062 0.0087
Brugia malayi PHD-finger family protein 0.005 0.0438 0.1046
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0072 0.0707 0.0681
Brugia malayi Cathepsin L-like precursor 0.0019 0.0062 0.0149
Leishmania major cathepsin L-like protease 0.0073 0.0716 0.1748
Entamoeba histolytica hypothetical protein 0.0073 0.072 1
Schistosoma mansoni Smad4 0.0024 0.0126 0.0433
Leishmania major mitochondrial DNA polymerase beta 0.0341 0.3963 1
Toxoplasma gondii cathepsin CPL 0.0019 0.0062 0.0733
Leishmania major cathepsin L-like protease 0.0019 0.0062 0.0087
Loa Loa (eye worm) hypothetical protein 0.0026 0.0142 0.0339
Echinococcus granulosus smad 0.0024 0.0126 0.0115
Schistosoma mansoni methyl-cpg binding protein mbd 0.0034 0.0246 0.0957
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0195 0.3575
Brugia malayi MH2 domain containing protein 0.0024 0.0126 0.0302
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0067 0.0639 0.1552
Entamoeba histolytica hypothetical protein 0.0073 0.072 1
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0195 0.3575
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0019 0.0062 0.0035
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0052 0.0455 0.1088
Leishmania major cathepsin L-like protease 0.0073 0.0716 0.1748
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0716 0.1748
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0019 0.0062 0.0149
Brugia malayi Bromodomain containing protein 0.0035 0.0253 0.0605
Loa Loa (eye worm) hypothetical protein 0.0052 0.0457 0.1092
Plasmodium falciparum cysteine proteinase falcipain 3 0.0019 0.0062 0.205
Echinococcus multilocularis Smad4 0.0024 0.0126 0.0099
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0716 0.1748
Plasmodium falciparum phd finger protein, putative 0.003 0.0195 1
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0099 0.1027 0.1003
Onchocerca volvulus Alhambra homolog 0.003 0.0195 0.0436
Echinococcus granulosus jumonji domain containing protein 0.0042 0.0339 0.0361
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0161 0.1786 0.4467
Trypanosoma cruzi ISWI complex protein 0.0031 0.0203 0.0445
Echinococcus granulosus fetal alzheimer antigen falz 0.0045 0.038 0.0409
Echinococcus granulosus geminin 0.0205 0.2309 0.2649
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0069 0.066 0.2774
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0019 0.0062 0.205
Brugia malayi Cathepsin L-like precursor 0.0019 0.0062 0.0149
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0608 0.2542
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0716 0.1748
Brugia malayi jmjC domain containing protein 0.004 0.0319 0.0763
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0045 0.038 0.1544
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0028 0.0067
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0608 0.2542
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0034 0.0246 0.0219
Echinococcus granulosus peregrin 0.0035 0.0253 0.0262
Trypanosoma cruzi cysteine peptidase, putative 0.0073 0.0716 0.1748
Plasmodium vivax vivapain-2 0.0019 0.0062 0.1587
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0048 0.0411 0.0973
Echinococcus granulosus tar DNA binding protein 0.0064 0.0608 0.0673
Echinococcus multilocularis tar DNA binding protein 0.0064 0.0608 0.0582
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0716 0.1748
Echinococcus granulosus methyl CpG binding domain protein 2 0.0034 0.0246 0.0253
Plasmodium vivax hypothetical protein, conserved 0.003 0.0195 0.7743
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0028 0.0001
Schistosoma mansoni jumonji domain containing protein 0.0079 0.0781 0.3303
Schistosoma mansoni zinc finger protein 0.0039 0.0307 0.1227
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0019 0.0062 0.205
Schistosoma mansoni lamin 0.0026 0.0148 0.0526
Schistosoma mansoni cellular tumor antigen P53 0.0106 0.112 0.4786
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0034 0.0244 0.0217
Schistosoma mansoni hypothetical protein 0.0073 0.072 0.3036
Echinococcus multilocularis lamin dm0 0.0026 0.0148 0.012
Echinococcus multilocularis cysteine protease 0.0019 0.0062 0.0035
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0069 0.066 0.0635
Loa Loa (eye worm) jmjC domain-containing protein 0.0062 0.0585 0.1398
Loa Loa (eye worm) hypothetical protein 0.0082 0.0824 0.197
Loa Loa (eye worm) cysteine protease 0.0019 0.0062 0.0149
Schistosoma mansoni hypothetical protein 0.0031 0.0203 0.0769
Echinococcus granulosus lysine specific demethylase 5A 0.004 0.0319 0.0338
Echinococcus multilocularis PHD finger protein rhinoceros 0.003 0.0195 0.0168
Loa Loa (eye worm) bromodomain containing protein 0.0036 0.0261 0.0624
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0058 0.0538 0.1296
Loa Loa (eye worm) hypothetical protein 0.0052 0.0455 0.1088
Schistosoma mansoni jumonji/arid domain-containing protein 0.004 0.0319 0.1277
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0028 0.0066
Echinococcus multilocularis tumor protein p63 0.0727 0.8641 0.8638
Brugia malayi Pre-SET motif family protein 0.0238 0.2719 0.6501
Loa Loa (eye worm) hypothetical protein 0.0106 0.112 0.2676
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0608 0.2542
Echinococcus granulosus cathepsin l1 0.0019 0.0062 0.004
Brugia malayi hypothetical protein 0.0073 0.072 0.1722
Loa Loa (eye worm) hypothetical protein 0.0026 0.0148 0.0353
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0148 0.0353
Plasmodium vivax vivapain-2 0.0019 0.0062 0.1587
Echinococcus multilocularis zinc finger protein 0.0039 0.0307 0.0281
Echinococcus multilocularis jumonji domain containing protein 0.0042 0.0339 0.0312
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0034 0.0244 0.095
Brugia malayi MH2 domain containing protein 0.0024 0.0126 0.0302
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0019 0.0062 0.0149
Brugia malayi F/Y-rich N-terminus family protein 0.0015 0.0011 0.0027
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0716 0.1748
Trypanosoma cruzi ISWI complex protein 0.0031 0.0203 0.0445
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0064 0.0608 0.1453
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0244 0.095
Loa Loa (eye worm) PHD-finger family protein 0.003 0.0195 0.0467
Brugia malayi jmjC domain containing protein 0.0099 0.1027 0.2456
Loa Loa (eye worm) RNA binding protein 0.0064 0.0608 0.1453
Leishmania major cathepsin L-like protease 0.0019 0.0062 0.0087
Brugia malayi MH1 domain containing protein 0.0024 0.0126 0.0302
Loa Loa (eye worm) MH2 domain-containing protein 0.0024 0.0126 0.0302
Brugia malayi Smad1 0.0024 0.0126 0.0302
Brugia malayi PHD-finger family protein 0.003 0.0195 0.0467
Loa Loa (eye worm) ctsf protein 0.0019 0.0062 0.0149
Echinococcus multilocularis smad 0.0024 0.0126 0.0099
Brugia malayi isocitrate dehydrogenase 0.0016 0.0028 0.0067
Leishmania major cathepsin L-like protease 0.0019 0.0062 0.0087
Schistosoma mansoni smad 0.0024 0.0126 0.0433
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0024 0.0126 0.0433
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0608 0.2542
Echinococcus granulosus cathepsin L cysteine proteinase 0.0019 0.0062 0.004
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.012 0.1287 0.1462
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0052 0.0455 0.1088
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0341 0.3963 1

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 4.1475 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 5.1735 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 12.5893 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of binding or entry into cells for Lassa Virus. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463114, AID540249] ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.