Detailed information for compound 1030172

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 301.815 | Formula: C11H12ClN3OS2
  • H donors: 1 H acceptors: 1 LogP: 1.68 Rotable bonds: 0
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C1NC2=Nc3c(CN2C1)c1c(s3)CCSC1.Cl
  • InChi: 1S/C11H11N3OS2.ClH/c15-9-4-14-3-6-7-5-16-2-1-8(7)17-10(6)13-11(14)12-9;/h1-5H2,(H,12,13,15);1H
  • InChiKey: TUVUFTCNKINDDB-UHFFFAOYSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0026 0.0035 0.0029
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0033 0.0062 0.0282
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0051 0.0127 0.0823
Trichomonas vaginalis phenylalanyl-tRNA synthetase alpha chain, putative 0.0111 0.035 0.2944
Loa Loa (eye worm) hypothetical protein 0.0033 0.0062 0.027
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0055 0.0375
Brugia malayi PHD-finger family protein 0.0028 0.0045 0.0167
Leishmania major phenylalanyl-tRNA synthetase alpha chain, putative 0.0331 0.116 1
Loa Loa (eye worm) hypothetical protein 0.0331 0.116 0.5863
Brugia malayi phosphofructokinase 0.0115 0.0365 0.1803
Schistosoma mansoni 6-phosphofructokinase 0.0115 0.0365 0.2142
Echinococcus granulosus geminin 0.0377 0.1329 0.6729
Echinococcus granulosus intermediate filament protein 0.006 0.0159 0.0777
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0051 0.0127 0.0743
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0268 0.0926 0.4664
Schistosoma mansoni cpg binding protein 0.0038 0.0079 0.0461
Brugia malayi Bromodomain containing protein 0.0082 0.0241 0.1167
Schistosoma mansoni hypothetical protein 0.0033 0.0062 0.0365
Schistosoma mansoni hypothetical protein 0.0033 0.0062 0.0365
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0033 0.006 0.0418
Schistosoma mansoni transcription factor LCR-F1 0.0037 0.0077 0.0454
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0058 0.0153 0.0742
Schistosoma mansoni hypothetical protein 0.0033 0.0062 0.0365
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0051 0.0127 0.0742
Loa Loa (eye worm) CXXC zinc finger family protein 0.0034 0.0064 0.028
Mycobacterium ulcerans 6-phosphofructokinase 0.0115 0.0365 0.0658
Echinococcus granulosus GPCR family 2 0.0033 0.0062 0.0282
Trichomonas vaginalis glucosylceramidase, putative 0.0185 0.0622 0.5314
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0033 0.0062 0.0055
Echinococcus granulosus survival motor neuron protein 1 0.0552 0.1971 1
Echinococcus granulosus cpg binding protein 0.0038 0.0079 0.0365
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0113 0.0354 0.1748
Echinococcus multilocularis phenylalanyl tRNA synthetase alpha chain B 0.0331 0.116 0.1153
Trichomonas vaginalis phosphofructokinase, putative 0.0115 0.0365 0.3079
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0055 0.0375
Brugia malayi phenylalanyl (f) trna synthetase protein 1 0.0331 0.116 0.5857
Schistosoma mansoni hypothetical protein 0.0479 0.1705 1
Echinococcus granulosus lamin 0.006 0.0159 0.0777
Schistosoma mansoni cpg binding protein 0.0034 0.0064 0.0376
Schistosoma mansoni phenylalanyl-tRNA synthetase mitochondrial 0.0161 0.0531 0.3116
Echinococcus multilocularis 6 phosphofructokinase 0.0115 0.0365 0.0359
Schistosoma mansoni lamin 0.006 0.0159 0.0935
Loa Loa (eye worm) hypothetical protein 0.0072 0.0204 0.0992
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0204 0.069 0.3476
Plasmodium vivax SET domain protein, putative 0.0033 0.006 0.0418
Echinococcus granulosus 6 phosphofructokinase 0.0115 0.0365 0.1824
Trichomonas vaginalis glucosylceramidase, putative 0.0268 0.0926 0.7964
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.0119 0.0698
Echinococcus granulosus lamin dm0 0.006 0.0159 0.0777
Loa Loa (eye worm) hypothetical protein 0.0552 0.1971 1
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0038 0.0081 0.0074
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0026 0.0035 0.0208
Loa Loa (eye worm) phenylalanyl-tRNA synthetase 0.0161 0.0531 0.2661
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0073 0.0207 0.1216
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.0587 0.501
Toxoplasma gondii Ferredoxin-fold anticodon binding domain-containing protein 0.0161 0.0531 0.4526
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0065 0.0181 0.0885
Echinococcus multilocularis neuropeptide s receptor 0.0491 0.1749 0.1743
Echinococcus multilocularis neuropeptide receptor A26 0.0491 0.1749 0.1743
Schistosoma mansoni lamin 0.006 0.0159 0.0935
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0037 0.0077 0.036
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0049 0.0119 0.0571
Brugia malayi 6-phosphofructokinase 0.0115 0.0365 0.1803
Toxoplasma gondii histone lysine methyltransferase SET1 0.0067 0.0189 0.1539
Entamoeba histolytica phosphofructokinase, putative 0.0115 0.0365 0.3079
Brugia malayi Calcitonin receptor-like protein seb-1 0.0105 0.0326 0.1602
Echinococcus multilocularis histone acetyltransferase MYST2 0.0058 0.0153 0.0146
Schistosoma mansoni zinc finger protein 0.0023 0.0024 0.014
Echinococcus multilocularis musashi 0.006 0.0159 0.0153
Trichomonas vaginalis phosphofructokinase, putative 0.0115 0.0365 0.3079
Treponema pallidum phenylalanyl-tRNA synthetase subunit alpha 0.0331 0.116 1
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0031 0.0055 0.0375
Mycobacterium leprae Probable phenylalanyl-tRNA synthetase, alpha chain PheS 0.022 0.075 1
Schistosoma mansoni bromodomain containing protein 0.0069 0.0195 0.1142
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0055 0.0088
Loa Loa (eye worm) MBCTL1 0.0058 0.0153 0.073
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0029 0.0046 0.0199
Schistosoma mansoni intermediate filament proteins 0.006 0.0159 0.0935
Plasmodium falciparum phenylalanine--tRNA ligase 0.0161 0.0531 0.4526
Entamoeba histolytica hypothetical protein 0.0037 0.0077 0.0571
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0049 0.0119 0.0571
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0012 0.0103
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0012 0.0009
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0012 0.0103
Loa Loa (eye worm) hypothetical protein 0.006 0.0159 0.0766
Echinococcus multilocularis survival motor neuron protein 1 0.0552 0.1971 0.1966
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0115 0.0365 0.315
Loa Loa (eye worm) hypothetical protein 0.0105 0.0326 0.1614
Schistosoma mansoni survival motor neuron protein 0.0113 0.0354 0.2078
Entamoeba histolytica phosphofructokinase, putative 0.0115 0.0365 0.3079
Giardia lamblia Phenylalanyl-tRNA synthetase alpha chain 0.0331 0.116 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0012 0.0103
Schistosoma mansoni hypothetical protein 0.0377 0.1329 0.7792
Onchocerca volvulus 0.0051 0.0127 0.0823
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0033 0.006 0.0351
Brugia malayi Pre-SET motif family protein 0.0222 0.0759 0.3812
Trichomonas vaginalis phosphofructokinase, putative 0.0115 0.0365 0.3079
Loa Loa (eye worm) hypothetical protein 0.0075 0.0217 0.1057
Trypanosoma brucei phenylalanyl-tRNA synthetase alpha chain, putative 0.0331 0.116 1
Plasmodium vivax phenylalanine--tRNA ligase alpha subunit, putative 0.0331 0.116 1
Brugia malayi mbt repeat family protein 0.0051 0.0127 0.0586
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0055 0.0375
Loa Loa (eye worm) intermediate filament protein 0.006 0.0159 0.0766
Loa Loa (eye worm) hypothetical protein 0.0029 0.0046 0.0187
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0031 0.0055 0.0375
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0055 0.0375
Trichomonas vaginalis glucosylceramidase, putative 0.0268 0.0926 0.7964
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0051 0.0127 0.012
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0268 0.0926 0.4672
Schistosoma mansoni sex comb on midleg homolog 0.0051 0.0127 0.0743
Wolbachia endosymbiont of Brugia malayi phenylalanyl-tRNA synthetase subunit alpha 0.1498 0.5455 1
Entamoeba histolytica hypothetical protein 0.0037 0.0077 0.0571
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0055 0.0375
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0058 0.0153 0.0146
Echinococcus granulosus neuropeptide receptor A26 0.0491 0.1749 0.8866
Brugia malayi Bromodomain containing protein 0.0041 0.009 0.0398
Mycobacterium tuberculosis Probable phenylalanyl-tRNA synthetase, alpha chain PheS 0.1498 0.5455 1
Trichomonas vaginalis glucosylceramidase, putative 0.0185 0.0622 0.5314
Loa Loa (eye worm) hypothetical protein 0.0051 0.0127 0.0598
Schistosoma mansoni hypothetical protein 0.0113 0.0354 0.2078
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0222 0.0759 0.3821
Loa Loa (eye worm) hypothetical protein 0.0028 0.0042 0.0167
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.0119 0.0698
Schistosoma mansoni phenylalanyl-tRNA synthetase subunit alpha 0.0331 0.116 0.6799
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.006 0.0351
Schistosoma mansoni hypothetical protein 0.0377 0.1329 0.7792
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.0587 0.501
Brugia malayi phenylalanyl-tRNA synthetase, mitochondrial precursor, putative 0.0161 0.0531 0.2651
Loa Loa (eye worm) phosphofructokinase 0.0115 0.0365 0.1814
Brugia malayi 6-phosphofructokinase 0.0115 0.0365 0.1803
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.006 0.0159 0.0766
Leishmania major ATP-dependent phosphofructokinase 0.0115 0.0365 0.315
Echinococcus granulosus polycomb protein SCMH1 0.0051 0.0127 0.061
Loa Loa (eye worm) hypothetical protein 0.0028 0.0042 0.0167
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0032 0.0058 0.0247
Trypanosoma cruzi phenylalanyl-tRNA synthetase alpha chain, putative 0.0331 0.116 1
Loa Loa (eye worm) hypothetical protein 0.0051 0.0127 0.0599
Brugia malayi Pre-SET motif family protein 0.0033 0.006 0.0245
Echinococcus multilocularis phenylalanyl tRNA synthetase 0.0161 0.0531 0.0525
Loa Loa (eye worm) PHD-finger family protein 0.0022 0.0021 0.0059
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0012 0.0014
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0055 0.0375
Onchocerca volvulus 0.006 0.0159 0.1227
Trichomonas vaginalis glucosylceramidase, putative 0.0268 0.0926 0.7964
Echinococcus granulosus dnaJ subfamily B 0.0479 0.1705 0.8646
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0033 0.0062 0.0257
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0055 0.0375
Trichomonas vaginalis phenylalanyl-tRNA synthetase alpha chain, putative 0.0331 0.116 1
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.0587 0.501
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.0119 0.0698
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0038 0.0081 0.0376
Toxoplasma gondii phosphofructokinase PFKII 0.0031 0.0055 0.0375
Echinococcus multilocularis lamin dm0 0.006 0.0159 0.0153
Loa Loa (eye worm) hypothetical protein 0.0058 0.0153 0.073
Loa Loa (eye worm) hypothetical protein 0.0043 0.0099 0.046
Loa Loa (eye worm) 6-phosphofructokinase 0.0115 0.0365 0.1814
Brugia malayi latrophilin 2 splice variant baaae 0.0072 0.0204 0.0979
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0051 0.0127 0.0742
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0105 0.0326 0.1614
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0049 0.0119 0.0547
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0012 0.0009
Loa Loa (eye worm) hypothetical protein 0.0047 0.0114 0.0534
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0115 0.0365 0.3079
Trichomonas vaginalis set domain proteins, putative 0.0253 0.0872 0.7491
Schistosoma mansoni hypothetical protein 0.0033 0.0062 0.0365
Onchocerca volvulus 0.0034 0.0064 0.0052
Echinococcus multilocularis SAM and MBT domain containing protein 0.0051 0.0127 0.012
Brugia malayi mbt repeat family protein 0.0051 0.0127 0.0586
Loa Loa (eye worm) hypothetical protein 0.0041 0.009 0.0413
Echinococcus granulosus phenylalanyl tRNA synthetase 0.0161 0.0531 0.267
Brugia malayi hypothetical protein 0.0552 0.1971 1
Echinococcus multilocularis polycomb protein SCMH1 0.0051 0.0127 0.012
Toxoplasma gondii 6-phosphofructokinase 0.0031 0.0055 0.0375
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0012 0.0103
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0055 0.0375
Plasmodium falciparum phenylalanine--tRNA ligase 0.0129 0.0416 0.3525
Entamoeba histolytica phosphofructokinase, putative 0.0115 0.0365 0.3079
Entamoeba histolytica hypothetical protein 0.0037 0.0077 0.0571
Plasmodium vivax phenylalanine--tRNA ligase, putative 0.0161 0.0531 0.4526
Schistosoma mansoni hypothetical protein 0.0022 0.0021 0.0122
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0031 0.0053 0.0234
Schistosoma mansoni 6-phosphofructokinase 0.0115 0.0365 0.2142
Echinococcus multilocularis zinc finger protein 0.0023 0.0024 0.0017
Trichomonas vaginalis phenylalanyl-tRNA synthetase alpha chain, putative 0.0111 0.035 0.2944
Echinococcus multilocularis dnaJ subfamily B 0.0479 0.1705 0.17
Trichomonas vaginalis phosphofructokinase, putative 0.0115 0.0365 0.3079
Echinococcus granulosus phenylalanyl tRNA synthetase alpha chain B 0.0331 0.116 0.5868
Schistosoma mansoni methyl-cpg binding protein mbd 0.0018 0.0007 0.004
Plasmodium vivax phenylalanine--tRNA ligase, putative 0.0111 0.035 0.2944
Schistosoma mansoni hypothetical protein 0.0312 0.1089 0.6384
Plasmodium falciparum phenylalanine--tRNA ligase alpha subunit 0.0331 0.116 1
Onchocerca volvulus 0.0113 0.0354 0.3628
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0055 0.0375
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0033 0.0062 0.0282
Schistosoma mansoni ap endonuclease 0.0019 0.0012 0.007
Entamoeba histolytica phenylalanyl-tRNA synthetase alpha subunit, putative 0.0331 0.116 1
Entamoeba histolytica hypothetical protein 0.0037 0.0077 0.0571
Echinococcus granulosus neuropeptide s receptor 0.0491 0.1749 0.8866
Echinococcus granulosus histone lysine methyltransferase setb 0.0051 0.0127 0.061
Onchocerca volvulus 0.0253 0.0872 1
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0037 0.0077 0.0071
Schistosoma mansoni hypothetical protein 0.0037 0.0077 0.0454
Loa Loa (eye worm) latrophilin receptor protein 2 0.0033 0.0062 0.027
Echinococcus multilocularis lamin 0.006 0.0159 0.0153
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0012 0.0009
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0049 0.0119 0.0112
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0115 0.0365 0.0658
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0105 0.0326 0.1602
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0029 0.0046 0.0039
Echinococcus multilocularis cpg binding protein 0.0038 0.0079 0.0072
Schistosoma mansoni methyl-cpg binding protein mbd 0.0018 0.0007 0.004
Echinococcus granulosus fetal alzheimer antigen falz 0.0026 0.0035 0.0145
Schistosoma mansoni cpg binding protein 0.0038 0.0079 0.0461
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0049 0.0119 0.0112
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0033 0.006 0.0053
Echinococcus multilocularis geminin 0.0377 0.1329 0.1323
Echinococcus granulosus zinc finger protein 0.0023 0.0024 0.0086
Echinococcus granulosus histone acetyltransferase MYST2 0.0058 0.0153 0.0742
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.0587 0.501
Schistosoma mansoni ap endonuclease 0.0019 0.0012 0.007
Brugia malayi intermediate filament protein 0.006 0.0159 0.0753
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0031 0.0055 0.0375
Echinococcus granulosus SAM and MBT domain containing protein 0.0051 0.0127 0.061
Brugia malayi Intermediate filament tail domain containing protein 0.006 0.0159 0.0753
Loa Loa (eye worm) hypothetical protein 0.0058 0.0155 0.0745
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0049 0.0119 0.056
Schistosoma mansoni myelin transcription factor 1 myt1 0.0058 0.0153 0.0894
Loa Loa (eye worm) mbt repeat family protein 0.0051 0.0127 0.0599
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0115 0.0365 0.315
Toxoplasma gondii phenylalanyl-tRNA synthetase alpha chain A, putative 0.0331 0.116 1
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.0587 0.501
Chlamydia trachomatis phenylalanine--tRNA ligase subunit alpha 0.1498 0.5455 1
Schistosoma mansoni sex comb on midleg homolog 0.0051 0.0127 0.0743
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0055 0.0375
Trichomonas vaginalis glucosylceramidase, putative 0.0268 0.0926 0.7964
Schistosoma mansoni phenylalanyl-tRNA synthetase subunit alpha 0.0111 0.035 0.2051
Mycobacterium ulcerans phenylalanyl-tRNA synthetase subunit alpha 0.1498 0.5455 1
Brugia malayi Latrophilin receptor protein 2 0.0033 0.0062 0.0257
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0204 0.069 0.0683
Brugia malayi CXXC zinc finger family protein 0.0034 0.0064 0.0266
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0031 0.0055 0.0375
Brugia malayi cytoplasmic intermediate filament protein 0.0032 0.0058 0.0233
Onchocerca volvulus Glucosylceramidase homolog 0.0176 0.0587 0.6492
Brugia malayi hypothetical protein 0.0037 0.0077 0.0334
Trichomonas vaginalis glucosylceramidase, putative 0.0268 0.0926 0.7964
Echinococcus multilocularis GPCR, family 2 0.0033 0.0062 0.0055
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0031 0.0055 0.0375
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0012 0.0005
Loa Loa (eye worm) 6-phosphofructokinase 0.0115 0.0365 0.1814
Trichomonas vaginalis glucosylceramidase, putative 0.0268 0.0926 0.7964
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0065 0.0181 0.0174
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0058 0.0153 0.0717
Onchocerca volvulus 0.006 0.0159 0.1227
Schistosoma mansoni hypothetical protein 0.0072 0.0204 0.1195
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0012 0.0026
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.0587 0.501
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0055 0.0088
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.0587 0.501
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0033 0.0062 0.0055

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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