Detailed information for compound 1191526

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 372.367 | Formula: C17H24O9
  • H donors: 4 H acceptors: 5 LogP: -2.1 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: COC1O[C@]2(O[C@@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O)C[C@H](C1=C)C(=O)C=C2C
  • InChi: 1S/C17H24O9/c1-7-4-10(19)9-5-17(7,25-15(23-3)8(9)2)26-16-14(22)13(21)12(20)11(6-18)24-16/h4,9,11-16,18,20-22H,2,5-6H2,1,3H3/t9-,11-,12-,13+,14-,15?,16+,17+/m1/s1
  • InChiKey: OMNBOKMNIVQDNN-MCCSOQQISA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium ulcerans carbamoyl phosphate synthase large subunit 0.0033 0.0443 0.0784
Echinococcus granulosus pyruvate kinase 0.0036 0.0502 0.0541
Onchocerca volvulus 0.0475 1 1
Brugia malayi Flap endonuclease-1 0.0028 0.0336 0.0336
Leishmania major ATP-dependent phosphofructokinase 0.0117 0.2266 0.9425
Schistosoma mansoni thyroid hormone receptor 0.0027 0.0304 0.0328
Schistosoma mansoni ap endonuclease 0.002 0.0164 0.0177
Schistosoma mansoni alzheimer's disease beta-amyloid related 0.0116 0.2232 0.2406
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0027 0.0304 0.0304
Loa Loa (eye worm) pyruvate kinase 0.0036 0.0502 0.0502
Wolbachia endosymbiont of Brugia malayi AICAR transformylase/IMP cyclohydrolase PurH 0.0254 0.5226 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0048 0.0777 0.1427
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0369 0.1609
Mycobacterium leprae Probable pyruvate kinase PykA 0.0036 0.0502 0.095
Brugia malayi CHD4 protein 0.0016 0.0075 0.0075
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0414 0.1805
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0027 0.0304 0.0328
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0164 0.0177
Schistosoma mansoni cpg binding protein 0.0035 0.0481 0.0519
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0232 0.4752 0.9086
Brugia malayi Bromodomain containing protein 0.0082 0.1506 0.1506
Echinococcus granulosus pyruvate kinase 0.0036 0.0502 0.0541
Schistosoma mansoni aldehyde dehydrogenase 0.0124 0.2404 0.2591
Entamoeba histolytica pyruvate kinase, putative 0.0025 0.0268 0.1039
Mycobacterium tuberculosis Probable bifunctional purine biosynthesis protein PurH: phosphoribosylaminoimidazolecarboxamide formyltransferase (AICAR transfo 0.0254 0.5226 1
Schistosoma mansoni methyl-cpg binding protein mbd 0.0018 0.0124 0.0133
Echinococcus granulosus thioredoxin glutathione reductase 0.0092 0.1721 0.1855
Onchocerca volvulus 0.0014 0.0036 0.0036
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0071 0.1259 0.1357
Giardia lamblia Flap structure-specific endonuclease 0.0028 0.0336 0.2849
Loa Loa (eye worm) CXXC zinc finger family protein 0.0031 0.0399 0.0399
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0415 0.181
Plasmodium vivax 6-phosphofructokinase, putative 0.0032 0.0414 0.2257
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0036 0.0036
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0014 0.0027 0.0092
Loa Loa (eye worm) CHromoDomain protein family member 0.0016 0.0075 0.0075
Onchocerca volvulus 0.0014 0.0036 0.0036
Schistosoma mansoni pyruvate kinase 0.0018 0.0125 0.0135
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0032 0.0414 0.8065
Toxoplasma gondii pyruvate kinase PyKII 0.0018 0.0125 0.0377
Trypanosoma brucei pyruvate kinase 1 0.0036 0.0502 0.2088
Trypanosoma brucei ISWI complex protein 0.0016 0.0083 0.021
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0014 0.0036 0.0134
Loa Loa (eye worm) hypothetical protein 0.0044 0.0673 0.0673
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0027 0.0304 0.0304
Leishmania major protein kinase, putative 0.0014 0.0027 0.0087
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0027 0.0304 0.0304
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0027 0.0304 0.0304
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0032 0.0414 0.8065
Plasmodium vivax carbamoyl phosphate synthetase, putative 0.0033 0.0443 0.2432
Echinococcus granulosus importin subunit beta 1 0.0031 0.0397 0.0428
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0369 0.1609
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0071 0.1259 0.5545
Echinococcus multilocularis chromobox protein 1 0.0075 0.1344 0.1448
Loa Loa (eye worm) hypothetical protein 0.0095 0.1786 0.1786
Loa Loa (eye worm) hypothetical protein 0.0095 0.1787 0.1787
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0124 0.2404 0.2591
Loa Loa (eye worm) oxidoreductase 0.0014 0.0036 0.0036
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0032 0.0415 0.2263
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0027 0.0304 0.0328
Brugia malayi Muscleblind-like protein 0.016 0.3192 0.3192
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0164 0.0164
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.0164 0.0575
Onchocerca volvulus 0.0037 0.0519 0.0519
Loa Loa (eye worm) hypothetical protein 0.0027 0.0304 0.0304
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0027 0.0304 0.0328
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0027 0.0304 0.0328
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0117 0.2266 0.433
Schistosoma mansoni methyl-cpg binding protein mbd 0.0018 0.0124 0.0133
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0013 0.0006 0.0006
Echinococcus granulosus aryl hydrocarbon receptor 0.0013 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0475 1 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0027 0.0304 0.0304
Brugia malayi photoreceptor-specific nuclear receptor 0.0027 0.0304 0.0304
Brugia malayi AMP-binding enzyme family protein 0.0048 0.0777 0.0777
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0164 0.0661
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0096 0.1808 0.7974
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0124 0.2404 0.2591
Entamoeba histolytica Flap nuclease, putative 0.0028 0.0336 0.1346
Trichomonas vaginalis antibiotic synthetase, putative 0.0014 0.0036 0.0134
Leishmania major pyruvate kinase 0.0036 0.0502 0.2068
Trichomonas vaginalis chromobox protein, putative 0.0075 0.1344 0.592
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0414 0.1805
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0209 0.4248 0.8114
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0164 0.0702
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0014 0.0036 0.0134
Echinococcus multilocularis pyruvate kinase 0.0036 0.0502 0.0541
Onchocerca volvulus 0.0027 0.0304 0.0304
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0053 0.0866 0.3586
Loa Loa (eye worm) hypothetical protein 0.0027 0.0304 0.0304
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0415 0.181
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0071 0.1259 0.5545
Schistosoma mansoni flap endonuclease-1 0.0025 0.0278 0.0299
Echinococcus multilocularis transfer RNA-Lys 0.0037 0.0519 0.0559
Onchocerca volvulus 0.0014 0.0036 0.0036
Brugia malayi Pyruvate kinase, muscle isozyme 0.0036 0.0502 0.0502
Schistosoma mansoni aspartate carbamoyltransferase 0.0033 0.0443 0.0477
Mycobacterium ulcerans acyl-CoA synthetase 0.0048 0.0777 0.1427
Schistosoma mansoni ap endonuclease 0.002 0.0164 0.0177
Mycobacterium ulcerans putative regulatory protein 0.0037 0.0519 0.093
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.033 0.6867 0.6867
Schistosoma mansoni acetyl-CoA synthetase 0.0014 0.0036 0.0039
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0469 0.0834
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0032 0.0415 0.1705
Loa Loa (eye worm) hypothetical protein 0.0166 0.3311 0.3311
Loa Loa (eye worm) hypothetical protein 0.0019 0.0138 0.0138
Schistosoma mansoni pyruvate kinase 0.0036 0.0502 0.0541
Brugia malayi PAS domain containing protein 0.0049 0.0796 0.0796
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0023 0.022 0.1101
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0028 0.0336 0.1378
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0048 0.0777 0.1427
Echinococcus granulosus methyl CpG binding domain protein 2 0.0018 0.0124 0.0133
Echinococcus multilocularis chromobox protein 1 0.0075 0.1344 0.1448
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0124 0.2404 0.4562
Brugia malayi 6-phosphofructokinase 0.0117 0.2266 0.2266
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0053 0.0866 0.0866
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0415 0.181
Loa Loa (eye worm) hypothetical protein 0.0041 0.0618 0.0618
Loa Loa (eye worm) hypothetical protein 0.0036 0.0512 0.0512
Trichomonas vaginalis phosphofructokinase, putative 0.0117 0.2266 1
Trichomonas vaginalis importin beta-1, putative 0.0025 0.027 0.1171
Brugia malayi Protein kinase domain containing protein 0.0096 0.1808 0.1808
Schistosoma mansoni hypothetical protein 0.033 0.6867 0.7401
Mycobacterium tuberculosis Probable oxidoreductase 0.0232 0.4752 0.9086
Loa Loa (eye worm) thioredoxin reductase 0.0092 0.1709 0.1709
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0014 0.0027 0.0092
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0096 0.1808 0.7946
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0049 0.0789 0.0789
Brugia malayi hypothetical protein 0.0014 0.0033 0.0033
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0071 0.1259 0.1357
Entamoeba histolytica acyl-coA synthetase, putative 0.0048 0.0777 0.3322
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0164 0.0702
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0032 0.0415 0.1705
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0039 0.0561 0.0605
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0415 0.181
Schistosoma mansoni aldehyde dehydrogenase 0.0124 0.2404 0.2591
Trypanosoma cruzi pyruvate kinase 2, putative 0.0036 0.0502 0.2195
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0027 0.0304 0.0304
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0066 0.1151 0.124
Loa Loa (eye worm) hypothetical protein 0.0134 0.2636 0.2636
Echinococcus multilocularis thioredoxin glutathione reductase 0.0092 0.1721 0.1855
Toxoplasma gondii NADPH-glutathione reductase 0.0032 0.0415 0.1599
Echinococcus multilocularis dual specificity 0.0096 0.1808 0.1949
Plasmodium vivax importin-beta 2, putative 0.0031 0.0397 0.2156
Onchocerca volvulus 0.0033 0.0438 0.0438
Mycobacterium leprae Probable bifunctional purine biosynthesis protein PurH : phosphoribosylaminoimidazolecarboxamide formyltransferase (aicar transf 0.0254 0.5226 1
Plasmodium falciparum importin beta, putative 0.0031 0.0397 0.2156
Mycobacterium tuberculosis Probable reductase 0.0209 0.4248 0.8114
Schistosoma mansoni serine/threonine protein kinase 0.0096 0.1808 0.1949
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0415 0.181
Entamoeba histolytica hypothetical protein 0.0096 0.1808 0.7946
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0032 0.0415 0.1698
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0048 0.0777 0.1427
Echinococcus multilocularis pyruvate kinase 0.0028 0.0339 0.0365
Brugia malayi Heterochromatin protein 1 0.0075 0.1344 0.1344
Mycobacterium ulcerans aldehyde dehydrogenase 0.0124 0.2404 0.4562
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0096 0.1808 0.7974
Mycobacterium ulcerans acyl-CoA synthetase 0.0048 0.0777 0.1427
Schistosoma mansoni coup transcription factor 0.0027 0.0304 0.0328
Entamoeba histolytica protein kinase, putative 0.0096 0.1808 0.7946
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0053 0.0866 0.3721
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0032 0.0414 0.1694
Leishmania major pyruvate kinase 0.0036 0.0502 0.2068
Trichomonas vaginalis chromobox protein, putative 0.0075 0.1344 0.592
Loa Loa (eye worm) hypothetical protein 0.0048 0.0777 0.0777
Plasmodium falciparum glutathione reductase 0.0032 0.0415 0.2263
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0053 0.0866 0.3805
Trichomonas vaginalis antibiotic synthetase, putative 0.0014 0.0036 0.0134
Entamoeba histolytica acyl-CoA synthetase, putative 0.0048 0.0777 0.3322
Echinococcus multilocularis pyruvate kinase 0.0036 0.0502 0.0541
Loa Loa (eye worm) hypothetical protein 0.0036 0.0512 0.0512
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0032 0.0415 0.181
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0071 0.1259 0.1259
Plasmodium vivax 6-phosphofructokinase, putative 0.0032 0.0414 0.2257
Schistosoma mansoni chromobox protein 0.0075 0.1344 0.1448
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0016 0.0074 0.0303
Echinococcus multilocularis cpg binding protein 0.0035 0.0481 0.0519
Brugia malayi nuclear receptor RXR 0.0014 0.0033 0.0033
Trypanosoma brucei trypanothione reductase 0.0092 0.1709 0.7504
Entamoeba histolytica protein kinase domain containing protein 0.0096 0.1808 0.7946
Schistosoma mansoni aryl hydrocarbon receptor 0.0049 0.0796 0.0858
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0027 0.0304 0.0304
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0027 0.0304 0.0304
Loa Loa (eye worm) hypothetical protein 0.0036 0.0502 0.0502
Loa Loa (eye worm) hypothetical protein 0.0027 0.0304 0.0304
Echinococcus multilocularis pyruvate kinase 0.0018 0.0125 0.0135
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0023 0.022 0.022
Onchocerca volvulus Pyruvate kinase homolog 0.0036 0.0502 0.0502
Schistosoma mansoni hypothetical protein 0.0441 0.9278 1
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0027 0.0304 0.0328
Entamoeba histolytica protein kinase, putative 0.0096 0.1808 0.7946
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0014 0.0027 0.0092
Echinococcus granulosus pyruvate kinase 0.0018 0.0125 0.0135
Mycobacterium ulcerans bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.0254 0.5226 1
Echinococcus granulosus mitogen activated protein kinase 3 0.0053 0.0866 0.0933
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0144 0.0614
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0033
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0049 0.0789 0.0789
Schistosoma mansoni zinc finger protein 0.0016 0.0083 0.0089
Entamoeba histolytica hypothetical protein 0.0025 0.027 0.1051
Loa Loa (eye worm) 6-phosphofructokinase 0.0117 0.2266 0.2266
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0053 0.0866 0.3586
Loa Loa (eye worm) phosphofructokinase 0.0117 0.2266 0.2266
Echinococcus multilocularis pyruvate kinase 0.0018 0.0125 0.0135
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0032 0.0415 0.2263
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0053 0.0866 0.3805
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0049 0.0789 0.085
Echinococcus multilocularis ecdysone induced protein 78C 0.0027 0.0304 0.0328
Echinococcus multilocularis pyruvate kinase 0.0018 0.0125 0.0135
Trypanosoma cruzi ISWI complex protein 0.0016 0.0083 0.0342
Brugia malayi nuclear hormone receptor 0.0027 0.0304 0.0304
Plasmodium vivax flap endonuclease 1, putative 0.0028 0.0336 0.1794
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0071 0.1259 0.5226
Echinococcus multilocularis dnaJ subfamily B 0.0441 0.9278 1
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0036 0.0036
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0164 0.0247
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.027 0.1171
Echinococcus granulosus dnaJ subfamily B 0.0441 0.9278 1
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0036 0.0502 0.0897
Toxoplasma gondii exonuclease III APE 0.002 0.0164 0.0542
Loa Loa (eye worm) hypothetical protein 0.016 0.3192 0.3192
Schistosoma mansoni nuclear hormone receptor 0.0027 0.0304 0.0328
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0027 0.0304 0.0304
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0028 0.0336 0.1462
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0032 0.0415 0.0447
Echinococcus granulosus chromobox protein 1 0.0075 0.1344 0.1448
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0117 0.2266 1
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0013 0.0007 0.0008
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0027 0.0304 0.0328
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.0164 0.0247
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0028 0.0336 0.1346
Trichomonas vaginalis phosphofructokinase, putative 0.0117 0.2266 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0027 0.0304 0.0328
Plasmodium vivax thioredoxin reductase, putative 0.0092 0.1709 1
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0414 0.1805
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0032 0.0415 0.1705
Loa Loa (eye worm) hypothetical protein 0.0076 0.1368 0.1368
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0209 0.4248 0.8114
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0117 0.2266 0.4296
Loa Loa (eye worm) pyruvate kinase-PB 0.0025 0.0268 0.0268
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0209 0.4248 0.8114
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0048 0.0777 0.1477
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0014 0.0027 0.0092
Echinococcus multilocularis flap endonuclease 1 0.0028 0.0336 0.0362
Onchocerca volvulus 0.0031 0.0399 0.0399
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0032 0.0415 0.0447
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0027 0.0304 0.0328
Echinococcus granulosus pyruvate kinase 0.0018 0.0125 0.0135
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0014 0.0036 0.0036
Trypanosoma cruzi ISWI complex protein 0.0016 0.0083 0.0342
Brugia malayi Bromodomain containing protein 0.0041 0.0616 0.0616
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0018 0.0124 0.0133
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0144 0.0614
Loa Loa (eye worm) hypothetical protein 0.025 0.514 0.514
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0209 0.4248 0.8114
Echinococcus multilocularis 6 phosphofructokinase 0.0117 0.2266 0.2442
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0032 0.0415 0.0415
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0032 0.0415 0.8084
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0144 0.0614
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0027 0.0304 0.0304
Schistosoma mansoni hypothetical protein 0.0016 0.0083 0.0089
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0053 0.0866 0.3805
Echinococcus multilocularis muscleblind protein 0.016 0.3192 0.3441
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0014 0.0033 0.0035
Loa Loa (eye worm) pyruvate kinase 0.0036 0.0502 0.0502
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0028 0.0336 0.1267
Brugia malayi 6-phosphofructokinase 0.0117 0.2266 0.2266
Brugia malayi ecdysteroid receptor 0.0027 0.0304 0.0304
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0014 0.0036 0.0039
Entamoeba histolytica Ran family GTPase 0.0023 0.022 0.0826
Toxoplasma gondii 6-phosphofructokinase 0.0032 0.0414 0.1595
Brugia malayi AMP-binding enzyme family protein 0.0048 0.0777 0.0777
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0164 0.0766
Schistosoma mansoni serine/threonine protein kinase 0.0053 0.0866 0.0933
Loa Loa (eye worm) hypothetical protein 0.0036 0.0512 0.0512
Schistosoma mansoni eyes absent homolog 0.0095 0.1786 0.1924
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0023 0.022 0.0826
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0027 0.0304 0.0328
Loa Loa (eye worm) hypothetical protein 0.0027 0.0304 0.0304
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0053 0.0866 0.3805
Echinococcus granulosus transcription factor Dp 1 0.0041 0.0614 0.0662
Entamoeba histolytica phosphofructokinase, putative 0.0117 0.2266 1
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0019 0.0138 0.0149
Trichomonas vaginalis mercuric reductase, putative 0.0032 0.0415 0.181
Loa Loa (eye worm) hypothetical protein 0.0048 0.0777 0.0777
Trichomonas vaginalis chromobox protein, putative 0.0045 0.0703 0.3083
Brugia malayi steroid hormone receptor 0.0027 0.0304 0.0304
Loa Loa (eye worm) hypothetical protein 0.0036 0.0512 0.0512
Loa Loa (eye worm) hypothetical protein 0.0095 0.1787 0.1787
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0014 0.0036 0.0058
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0063 0.0253
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0014 0.0036 0.0058
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0032 0.0415 0.2263
Echinococcus multilocularis snurportin 1 0.033 0.6867 0.7401
Schistosoma mansoni importin beta-1 0.0031 0.0397 0.0428
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0032 0.0415 0.0495
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0049 0.0789 0.085
Leishmania major hypothetical protein, conserved 0.0016 0.0083 0.0322
Loa Loa (eye worm) 6-phosphofructokinase 0.0117 0.2266 0.2266
Trichomonas vaginalis phosphofructokinase, putative 0.0117 0.2266 1
Leishmania major 4-coumarate:coa ligase-like protein 0.0048 0.0777 0.3215
Plasmodium falciparum flap endonuclease 1 0.0028 0.0336 0.1794
Echinococcus granulosus chromobox protein 1 0.0075 0.1344 0.1448
Plasmodium falciparum glutathione reductase 0.0092 0.1709 1
Loa Loa (eye worm) runx1 0.006 0.1017 0.1017
Treponema pallidum NADH oxidase 0.0032 0.0415 0.1192
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0164 0.0766
Echinococcus granulosus pyruvate kinase 0.0018 0.0125 0.0135
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0027 0.0304 0.0328
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0066 0.1151 0.124
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0014 0.0036 0.0126
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0164 0.0164
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0117 0.2266 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.0789 0.085
Onchocerca volvulus 0.0014 0.0036 0.0036
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0023 0.0232 0.0232
Trichomonas vaginalis ran, putative 0.0023 0.022 0.0949
Brugia malayi Nuclear hormone receptor-like 1 0.0014 0.0033 0.0033
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0144 0.0614
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0074 0.0303
Echinococcus granulosus ecdysone induced protein 78C 0.0027 0.0304 0.0328
Leishmania major trypanothione reductase 0.0092 0.1709 0.7104
Loa Loa (eye worm) hypothetical protein 0.0095 0.1786 0.1786
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0027 0.0304 0.0328
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0032 0.0414 0.1595
Loa Loa (eye worm) hypothetical protein 0.0036 0.0512 0.0512
Loa Loa (eye worm) hypothetical protein 0.0031 0.0397 0.0397
Trichomonas vaginalis glutathione reductase, putative 0.0032 0.0415 0.181
Giardia lamblia Pyruvate kinase 0.0036 0.0502 0.5085
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0414 0.1805
Brugia malayi hypoxia-induced factor 1 0.0153 0.3034 0.3034
Entamoeba histolytica phosphofructokinase, putative 0.0117 0.2266 1
Leishmania major carbamoyl-phosphate synthase, putative 0.0033 0.0443 0.1823
Brugia malayi phosphofructokinase 0.0117 0.2266 0.2266
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0634 0.2779
Loa Loa (eye worm) hypothetical protein 0.0475 1 1
Echinococcus multilocularis muscleblind protein 1 0.016 0.3192 0.3441
Loa Loa (eye worm) hypothetical protein 0.0033 0.0438 0.0438
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0144 0.0614
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0164 0.0702
Echinococcus multilocularis mitogen activated protein kinase 0.0053 0.0866 0.0933
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0027 0.0304 0.0328
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0032 0.0415 0.1698
Brugia malayi Amyloid A4 extracellular domain containing protein 0.0317 0.6596 0.6596
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0117 0.2266 1
Plasmodium vivax glutathione reductase, putative 0.0092 0.1709 1
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0634 0.2779
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0027 0.0304 0.0304
Echinococcus granulosus GTP binding nuclear protein Ran 0.0023 0.022 0.0237
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0027 0.0304 0.0328
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.022 0.0949
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0023 0.022 0.022
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0032 0.0415 0.1599
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0023 0.0232 0.0232
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0033
Echinococcus granulosus single minded 2 0.0037 0.0519 0.0559
Giardia lamblia Kinase, CMGC MAPK 0.0053 0.0866 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0124 0.2404 0.4562
Schistosoma mansoni bromodomain containing protein 0.007 0.1234 0.133
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0016 0.0075 0.0081
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0071 0.1259 0.1259
Brugia malayi AMP-binding enzyme family protein 0.0048 0.0777 0.0777
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0027 0.0304 0.0328
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0027 0.0304 0.0328
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0014 0.0033 0.0035
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0013 0.0006 0.0006
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0039 0.0561 0.0605
Loa Loa (eye worm) hypothetical protein 0.0067 0.118 0.118
Plasmodium falciparum pyruvate kinase 0.0036 0.0502 0.2783
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0019 0.0138 0.0149
Loa Loa (eye worm) glutathione reductase 0.0092 0.1709 0.1709
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0036 0.0512 0.0916
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.002 0.0164 0.0528
Schistosoma mansoni lozenge 0.006 0.1017 0.1096
Trypanosoma cruzi pyruvate kinase 2, putative 0.0036 0.0502 0.2195
Trichomonas vaginalis chromobox protein, putative 0.0045 0.0703 0.3083
Brugia malayi SET domain containing protein 0.0013 0.0007 0.0007
Loa Loa (eye worm) bromodomain containing protein 0.0019 0.0138 0.0138
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.0006
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0164 0.0575
Echinococcus multilocularis importin subunit beta 1 0.0031 0.0397 0.0428
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0032 0.0415 0.1698
Leishmania major 4-coumarate:coa ligase-like protein 0.0048 0.0777 0.3215
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0414 0.1805
Toxoplasma gondii thioredoxin reductase 0.0092 0.1709 0.7067
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0014 0.0036 0.0058
Brugia malayi hypothetical protein 0.0095 0.1786 0.1786
Toxoplasma gondii phosphofructokinase PFKII 0.0032 0.0414 0.1595
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0124 0.2404 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0469 0.0834
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.027 0.1171
Toxoplasma gondii histone lysine methyltransferase SET1 0.0061 0.1053 0.4296
Plasmodium falciparum thioredoxin reductase 0.0032 0.0415 0.2263
Echinococcus granulosus histone lysine methyltransferase setb 0.0019 0.0138 0.0149
Plasmodium falciparum pyruvate kinase 2 0.0018 0.0125 0.0533
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0048 0.0777 0.1427
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0033
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0023 0.022 0.1284
Plasmodium falciparum acyl-CoA synthetase 0.0036 0.0512 0.2842
Loa Loa (eye worm) PHD-finger family protein 0.0022 0.0207 0.0207
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0164 0.0702
Brugia malayi nuclear receptor NHR-88 0.0027 0.0304 0.0304
Echinococcus multilocularis aryl hydrocarbon receptor 0.0013 0.0006 0.0006
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0053 0.0866 0.3504
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0023 0.022 0.0778
Schistosoma mansoni 6-phosphofructokinase 0.0117 0.2266 0.2442
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0036 0.0512 1
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0092 0.1709 0.3224
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0032 0.0415 0.073
Loa Loa (eye worm) pyruvate kinase 0.0036 0.0502 0.0502
Echinococcus multilocularis transcription factor Dp 1 0.0041 0.0614 0.0662
Toxoplasma gondii pyruvate kinase PyK1 0.0036 0.0502 0.1967
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0048 0.0777 0.1427
Echinococcus granulosus FTZ F1 alpha 0.0027 0.0304 0.0328
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.022 0.0949
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.0789 0.085
Echinococcus granulosus flap endonuclease 1 0.0028 0.0336 0.0362
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0209 0.4248 0.8125
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0014 0.0033 0.0033
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0048 0.0777 0.1477
Brugia malayi glutathione reductase 0.0092 0.1709 0.1709
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0045 0.0703 0.0703
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0144 0.0614
Echinococcus granulosus fetal alzheimer antigen falz 0.0026 0.0289 0.0312
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0027 0.0304 0.0328
Echinococcus multilocularis FTZ F1 alpha 0.0027 0.0304 0.0328
Leishmania major 4-coumarate:coa ligase-like protein 0.0048 0.0777 0.3215
Loa Loa (eye worm) hypothetical protein 0.0048 0.0777 0.0777
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0032 0.0415 0.2263
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0014 0.0036 0.0134
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0027 0.0304 0.0304
Onchocerca volvulus Protein ultraspiracle homolog 0.0027 0.0304 0.0304
Schistosoma mansoni ran 0.0023 0.022 0.0237
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0144 0.0614
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0232 0.4752 0.9091
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0027 0.0304 0.0304
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0096 0.1808 0.1808
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0071 0.1259 0.5484
Loa Loa (eye worm) steroid hormone receptor 0.0027 0.0304 0.0304
Trichomonas vaginalis phosphofructokinase, putative 0.0117 0.2266 1
Loa Loa (eye worm) hypothetical protein 0.016 0.3192 0.3192
Toxoplasma gondii carbamoylphosphate synthetase 0.0033 0.0443 0.1718
Schistosoma mansoni zinc finger protein 0.0023 0.022 0.0237
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0071 0.1259 0.5484
Schistosoma mansoni chromobox protein 0.0075 0.1344 0.1448
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0036 0.0512 0.0916
Trypanosoma cruzi trypanothione reductase, putative 0.0092 0.1709 0.7537
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0014 0.0036 0.0036
Loa Loa (eye worm) hypoxia-induced factor 1 0.0153 0.3034 0.3034
Brugia malayi Nuclear hormone receptor-like 1 0.0027 0.0304 0.0304
Echinococcus multilocularis thyroid hormone receptor alpha 0.0027 0.0304 0.0328
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0032 0.0415 0.181
Schistosoma mansoni pyruvate kinase 0.0036 0.0502 0.0541
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0032 0.0415 0.073
Schistosoma mansoni hypothetical protein 0.0022 0.0207 0.0223
Echinococcus granulosus dual specificity 0.0096 0.1808 0.1949
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0415 0.181
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0033
Trichomonas vaginalis pyruvate kinase, putative 0.0036 0.0502 0.2195
Echinococcus granulosus 6 phosphofructokinase 0.0117 0.2266 0.2442
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0032 0.0415 0.0447
Leishmania major GTP-binding protein, putative 0.0023 0.022 0.0895
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0144 0.0614
Leishmania major acetyl-CoA synthetase, putative 0.0014 0.0036 0.0126
Loa Loa (eye worm) flap endonuclease-1 0.0028 0.0336 0.0336
Trypanosoma cruzi trypanothione reductase, putative 0.0032 0.0415 0.181
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0027 0.0304 0.0304
Mycobacterium ulcerans pyruvate kinase 0.0036 0.0502 0.0897
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0023 0.022 0.1101
Mycobacterium ulcerans acyl-CoA synthetase 0.0048 0.0777 0.1427
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0032 0.0415 0.073
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0027 0.0304 0.0304
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.0789 0.085
Loa Loa (eye worm) hypothetical protein 0.0047 0.0755 0.0755
Plasmodium vivax pyruvate kinase, putative 0.0036 0.0502 0.2783
Echinococcus granulosus zinc finger protein 0.0023 0.022 0.0237
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0027 0.0304 0.0304
Loa Loa (eye worm) hypothetical protein 0.0014 0.0036 0.0036
Schistosoma mansoni retinoic acid receptor RXR 0.0027 0.0304 0.0328
Toxoplasma gondii HEAT repeat-containing protein 0.0031 0.0397 0.1524
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0026 0.0289 0.0312
Onchocerca volvulus Pyruvate kinase homolog 0.0036 0.0502 0.0502
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0027 0.0304 0.0328
Echinococcus granulosus muscleblind protein 0.016 0.3192 0.3441
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0049 0.0789 0.085
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0049 0.0789 0.085
Echinococcus multilocularis zinc finger protein 0.0023 0.022 0.0237
Mycobacterium ulcerans hypothetical protein 0.0048 0.0777 0.1427
Brugia malayi hypothetical protein 0.0014 0.0033 0.0033
Brugia malayi CXXC zinc finger family protein 0.0031 0.0399 0.0399
Entamoeba histolytica acyl-CoA synthetase, putative 0.0048 0.0777 0.3322
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0027 0.0304 0.0304
Schistosoma mansoni cpg binding protein 0.0035 0.0481 0.0519
Loa Loa (eye worm) heterochromatin protein 1 0.0075 0.1344 0.1344
Leishmania major acetyl-CoA synthetase, putative 0.0014 0.0036 0.0126
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0032 0.0414 0.2257
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0014 0.0036 0.0134
Loa Loa (eye worm) hypothetical protein 0.0042 0.0634 0.0634
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0027 0.0304 0.0304
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0032 0.0414 0.2257
Trichomonas vaginalis pyruvate kinase, putative 0.0036 0.0502 0.2195
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0014 0.0036 0.0036
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0414 0.1805
Loa Loa (eye worm) hypothetical protein 0.0027 0.0304 0.0304
Brugia malayi PHD-finger family protein 0.0028 0.0344 0.0344
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0027 0.0304 0.0328
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0032 0.0415 0.1698
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0027 0.0304 0.0304
Schistosoma mansoni RAR-like nuclear receptor 0.0027 0.0304 0.0328
Brugia malayi Thioredoxin reductase 0.0092 0.1709 0.1709
Onchocerca volvulus 0.0048 0.0777 0.0777
Plasmodium falciparum thioredoxin reductase 0.0092 0.1709 1
Brugia malayi Steroid receptor seven-up type 2 0.0027 0.0304 0.0304
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0032 0.0415 0.1705
Schistosoma mansoni steroid hormone receptor ad4bp 0.0027 0.0304 0.0328
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0071 0.1259 0.1357
Schistosoma mansoni single-minded 0.0049 0.0796 0.0858
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0014 0.0033 0.0035
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0032 0.0415 0.0495
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0014 0.0033 0.0035
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0866 0.3805
Schistosoma mansoni thyroid hormone receptor 0.0027 0.0304 0.0328
Brugia malayi hypothetical protein 0.0166 0.3311 0.3311
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0027 0.0304 0.0304
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0016 0.0075 0.0081
Schistosoma mansoni cpg binding protein 0.0031 0.0399 0.043
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0066 0.115 0.124
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0032 0.0415 0.073
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0013 0.0006 0.0006
Echinococcus granulosus snurportin 1 0.033 0.6867 0.7401
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0027 0.0304 0.0304
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0032 0.0414 0.3897
Onchocerca volvulus Bile acid receptor homolog 0.0027 0.0304 0.0304
Brugia malayi Pyruvate kinase, M2 isozyme 0.0036 0.0502 0.0502
Brugia malayi Importin beta-1 subunit 0.0031 0.0397 0.0397
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0036 0.0036
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0027 0.0304 0.0328
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0019 0.0138 0.0149
Brugia malayi Nuclear hormone receptor-like 1 0.0014 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0025 0.0268 0.0268
Wolbachia endosymbiont of Brugia malayi carbamoyl phosphate synthase large subunit 0.0033 0.0443 0.055
Brugia malayi MAP kinase sur-1 0.0053 0.0866 0.0866
Plasmodium vivax acyl-CoA synthetase, putative 0.0036 0.0512 0.2842
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0014 0.0036 0.0036
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0232 0.4752 0.9086
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.0634 0.0634
Brugia malayi RNA, U transporter 1 0.0088 0.163 0.163
Leishmania major protein kinase, putative 0.0014 0.0027 0.0087
Plasmodium vivax pyruvate kinase 2, putative 0.0018 0.0125 0.0533
Onchocerca volvulus 0.0013 0.0007 0.0007
Echinococcus multilocularis mitogen activated protein kinase 3 0.0053 0.0866 0.0933
Brugia malayi chromobox protein homolog 3 0.0042 0.0634 0.0634
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0023 0.022 0.0237
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.0397 0.1618
Onchocerca volvulus Pyruvate kinase homolog 0.0036 0.0502 0.0502
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0048 0.0777 0.1427
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0866 0.3805
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0032 0.0414 0.1187
Loa Loa (eye worm) hypothetical protein 0.0027 0.0304 0.0304
Mycobacterium ulcerans aldehyde dehydrogenase 0.0124 0.2404 0.4562
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.0397 0.1618
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0032 0.0414 0.1805
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0033
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0096 0.1808 0.7515
Chlamydia trachomatis pyruvate kinase 0.0036 0.0502 0.9804
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0866 0.3805
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0164 0.0177
Plasmodium falciparum carbamoyl phosphate synthetase 0.0033 0.0443 0.2432
Trypanosoma brucei pyruvate kinase 1, putative 0.0036 0.0502 0.2088
Mycobacterium tuberculosis Probable dehydrogenase 0.0209 0.4248 0.8114
Schistosoma mansoni 6-phosphofructokinase 0.0117 0.2266 0.2442
Trypanosoma cruzi importin beta-1 subunit, putative 0.0025 0.027 0.1171
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0014 0.0036 0.0039
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0026 0.0289 0.0312
Echinococcus multilocularis Protein lozenge 0.006 0.1017 0.1096
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0016 0.0075 0.0081
Echinococcus granulosus mitogen activated protein kinase 0.0053 0.0866 0.0933
Leishmania major importin beta-1 subunit, putative 0.0025 0.027 0.1104
Toxoplasma gondii aldehyde dehydrogenase 0.0124 0.2404 1
Giardia lamblia NADH oxidase lateral transfer candidate 0.0032 0.0415 0.391
Entamoeba histolytica phosphofructokinase, putative 0.0117 0.2266 1
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0866 0.3805
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0469 0.0834
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0027 0.0304 0.0304
Schistosoma mansoni ran 0.0023 0.022 0.0237
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0469 0.0834
Mycobacterium ulcerans 6-phosphofructokinase 0.0117 0.2266 0.4296
Trichomonas vaginalis flap endonuclease-1, putative 0.0028 0.0336 0.1462
Brugia malayi bHLH-PAS transcription factor 0.0037 0.0519 0.0519
Echinococcus granulosus cpg binding protein 0.0035 0.0481 0.0519
Trypanosoma brucei protein kinase, putative 0.0053 0.0866 0.3721
Onchocerca volvulus 0.0013 0.0006 0.0006
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0027 0.0304 0.0304

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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