Detailed information for compound 1246186

Basic information

Technical information
  • TDR Targets ID: 1246186
  • Name: 1-[2-[4-(2-hydroxybenzoyl)pyrazol-1-yl]-2-oxo ethyl]pyrrolidin-2-one
  • MW: 313.308 | Formula: C16H15N3O4
  • H donors: 1 H acceptors: 5 LogP: 1.25 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(n1ncc(c1)C(=O)c1ccccc1O)CN1CCCC1=O
  • InChi: 1S/C16H15N3O4/c20-13-5-2-1-4-12(13)16(23)11-8-17-19(9-11)15(22)10-18-7-3-6-14(18)21/h1-2,4-5,8-9,20H,3,6-7,10H2
  • InChiKey: PXCXKHMAQLGENH-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 1-[2-[4-(2-hydroxybenzoyl)pyrazol-1-yl]-2-oxo-ethyl]pyrrolidin-2-one
  • 1-[2-[4-[(2-hydroxyphenyl)-oxomethyl]-1-pyrazolyl]-2-oxoethyl]-2-pyrrolidinone
  • 1-[2-[4-(2-hydroxybenzoyl)pyrazol-1-yl]-2-keto-ethyl]-2-pyrrolidone
  • 1-[2-[4-(2-hydroxyphenyl)carbonylpyrazol-1-yl]-2-oxo-ethyl]pyrrolidin-2-one
  • ZINC06560669
  • T5364825

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0105 0.0973 0.1903
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0037 0.0259 0.2019
Echinococcus multilocularis lamin 0.0057 0.0474 0.0792
Loa Loa (eye worm) glutathione reductase 0.0046 0.0358 0.0651
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0036 0.0253 0.0602
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.017 0.0308
Trypanosoma cruzi DNA polymerase eta, putative 0.0038 0.0277 0.7714
Echinococcus multilocularis muscleblind protein 1 0.0147 0.1414 0.2522
Schistosoma mansoni alpha-glucosidase 0.0142 0.1357 0.3238
Echinococcus multilocularis survival motor neuron protein 1 0.0536 0.5477 1
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0091 0.2521
Brugia malayi cytoplasmic intermediate filament protein 0.0031 0.0197 0.036
Mycobacterium ulcerans aldehyde dehydrogenase 0.0134 0.1278 0.3049
Trypanosoma brucei unspecified product 0.0026 0.0153 0.4243
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0134 0.1278 0.2271
Echinococcus multilocularis peregrin 0.0032 0.021 0.0305
Echinococcus granulosus cpg binding protein 0.003 0.0187 0.0263
Schistosoma mansoni lamin 0.0057 0.0474 0.1129
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0016 0.0044 0.1197
Echinococcus granulosus lysine specific demethylase 5A 0.0036 0.0253 0.0384
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0016 0.0044 0.1197
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.043 0.4366 0.7972
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0277 0.7714
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0014 0.002 0.0513
Echinococcus granulosus lysosomal alpha glucosidase 0.0165 0.1597 0.2858
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0091 0.0144
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0105 0.0973 0.2242
Echinococcus granulosus thioredoxin glutathione reductase 0.0046 0.0358 0.0578
Mycobacterium ulcerans DNA polymerase IV 0.0038 0.0277 0.0657
Brugia malayi polk-prov protein 0.0012 0.0002 0.0003
Toxoplasma gondii aldehyde dehydrogenase 0.0134 0.1278 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.0099 0.0907 0.1656
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0039 0.0282 0.0573
Mycobacterium tuberculosis Conserved hypothetical protein 0.0413 0.4189 1
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0062 0.0527 0.0889
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.002 0.0091 0.2213
Loa Loa (eye worm) inositol-1 0.0036 0.0258 0.0468
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0318 0.3203 0.641
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0258 0.7182
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0044 0.1197
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0259 0.7227
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0044 0.1197
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0044 0.1197
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0253 0.047
Schistosoma mansoni hypothetical protein 0.0031 0.0203 0.0482
Treponema pallidum exodeoxyribonuclease (exoA) 0.002 0.0091 0.015
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0031 0.0203 0.0293
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0038 0.0277 0.0517
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.0258 1
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0044 0.1197
Loa Loa (eye worm) jmjC domain-containing protein 0.0036 0.0253 0.0459
Giardia lamblia Transglutaminase/protease, putative 0.0413 0.4189 1
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.019 0.1866 0.3405
Echinococcus granulosus geminin 0.0349 0.352 0.6398
Brugia malayi acetyltransferase, GNAT family protein 0.0141 0.1354 0.2472
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0253 0.0385
Trypanosoma brucei DNA polymerase IV, putative 0.0038 0.0277 0.7714
Mycobacterium leprae Conserved hypothetical protein 0.0413 0.4189 1
Trypanosoma brucei trypanothione reductase 0.0046 0.0358 1
Trichomonas vaginalis glutathione reductase, putative 0.0016 0.0044 0.0049
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0134 0.1278 0.2977
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0014 0.002 0.0513
Trichomonas vaginalis set domain proteins, putative 0.0489 0.4985 1
Echinococcus multilocularis lysine specific demethylase 5A 0.0034 0.0236 0.0353
Schistosoma mansoni hypothetical protein 0.0349 0.352 0.8403
Onchocerca volvulus 0.0057 0.0474 0.0455
Trypanosoma brucei hypothetical protein, conserved 0.0039 0.0282 0.7861
Trichomonas vaginalis maltase-glucoamylase, putative 0.0037 0.0259 0.0482
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0282 0.0669
Schistosoma mansoni terminal deoxycytidyl transferase 0.0038 0.0277 0.0657
Plasmodium vivax hypothetical protein, conserved 0.0028 0.0174 0.328
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0117 0.1096 0.2537
Mycobacterium ulcerans putative transglutaminase-like protein 0.0413 0.4189 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0277 0.7714
Loa Loa (eye worm) hypothetical protein 0.0049 0.0385 0.0701
Mycobacterium ulcerans lipase LipD 0.0039 0.0282 0.0669
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0141 0.1354 0.2411
Echinococcus granulosus beta LACTamase domain containing family member 0.0039 0.0282 0.0437
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0259 0.0482
Brugia malayi Bromodomain containing protein 0.0032 0.021 0.0384
Trypanosoma brucei PAB1-binding protein , putative 0.0024 0.0132 0.366
Schistosoma mansoni cpg binding protein 0.003 0.0187 0.0443
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0258 0.2006
Trichomonas vaginalis conserved hypothetical protein 0.0175 0.171 0.3403
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.019 0.1866 0.3354
Mycobacterium tuberculosis Conserved protein 0.0039 0.0282 0.0573
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0044 0.1197
Mycobacterium tuberculosis Probable reductase 0.0105 0.0973 0.2242
Plasmodium vivax glutathione reductase, putative 0.0046 0.0358 0.6785
Echinococcus multilocularis Transglutaminase 0.0413 0.4189 0.7629
Echinococcus granulosus PHD finger protein rhinoceros 0.0028 0.0174 0.0239
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0038 0.0277 0.0428
Echinococcus multilocularis ubiquitin specific protease 41 0.0036 0.0253 0.0385
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0016 0.0044 0.0102
Mycobacterium ulcerans hypothetical protein 0.0413 0.4189 1
Echinococcus granulosus dnaJ subfamily B 0.0399 0.4044 0.7363
Brugia malayi ImpB/MucB/SamB family protein 0.0038 0.0277 0.0505
Entamoeba histolytica deoxycytidyl transferase, putative 0.0038 0.0277 0.0807
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0039 0.0282 0.0573
Loa Loa (eye worm) jmjC domain-containing protein 0.0059 0.0489 0.0891
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0282 0.0528
Brugia malayi Pre-SET motif family protein 0.043 0.4366 0.7972
Plasmodium falciparum thioredoxin reductase 0.0016 0.0044 0.1197
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0165 0.1597 0.2914
Mycobacterium tuberculosis Probable esterase LipL 0.0039 0.0282 0.0573
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0253 0.7064
Treponema pallidum fructose-bisphosphate aldolase 0.0318 0.3203 1
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0386 0.0919
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0093 0.0848 0.1479
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.019 0.1866 0.4453
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0282 0.0528
Echinococcus multilocularis cpg binding protein 0.003 0.0187 0.0263
Loa Loa (eye worm) hypothetical protein 0.0147 0.1414 0.258
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0091 0.2521
Trypanosoma brucei glycosyl hydrolase-like protein 0.0014 0.002 0.0513
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0036 0.0253 0.0734
Brugia malayi jmjC domain containing protein 0.0093 0.0848 0.1548
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0253 0.7064
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.0277 0.7714
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0277 0.7714
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0016 0.0044 0.0334
Echinococcus multilocularis dnaJ subfamily B 0.0399 0.4044 0.7363
Mycobacterium ulcerans aldehyde dehydrogenase 0.0134 0.1278 0.3049
Schistosoma mansoni hypothetical protein 0.0028 0.0174 0.0412
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0028 0.0174 0.0412
Mycobacterium ulcerans DNA polymerase IV 0.0038 0.0277 0.0657
Schistosoma mansoni hypothetical protein 0.0349 0.352 0.8403
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0318 0.3203 0.641
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0282 0.0528
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.0259 0.0752
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0318 0.3203 0.641
Brugia malayi jmjC domain containing protein 0.0036 0.0253 0.0462
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0016 0.0044 0.0812
Mycobacterium ulcerans esterase/lipase LipP 0.0039 0.0282 0.0669
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0046 0.0358 0.0757
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0042 0.0312 0.0588
Loa Loa (eye worm) hypothetical protein 0.018 0.1761 0.3214
Mycobacterium tuberculosis Probable lipase LipE 0.0039 0.0282 0.0573
Plasmodium falciparum thioredoxin reductase 0.0046 0.0358 1
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0156 0.1502 0.3234
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0031 0.0203 0.0293
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0282 0.7861
Schistosoma mansoni jumonji/arid domain-containing protein 0.0036 0.0253 0.06
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0039 0.0282 0.0515
Echinococcus granulosus histone acetyltransferase KAT2B 0.0042 0.0312 0.0493
Loa Loa (eye worm) hypothetical protein 0.0031 0.0203 0.0369
Echinococcus granulosus Transglutaminase 0.0413 0.4189 0.7629
Brugia malayi MH2 domain containing protein 0.0135 0.1291 0.2357
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0037 0.0259 0.0471
Brugia malayi Latrophilin receptor protein 2 0.0031 0.0203 0.0371
Loa Loa (eye worm) beta-lactamase 0.0039 0.0282 0.0512
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.0091 0.0225
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0258 0.0393
Loa Loa (eye worm) hypothetical protein 0.0028 0.0166 0.03
Trypanosoma brucei unspecified product 0.0038 0.0277 0.7714
Schistosoma mansoni hypothetical protein 0.0031 0.0203 0.0482
Entamoeba histolytica acetyltransferase, GNAT family 0.0038 0.0276 0.0804
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0039 0.0282 0.0669
Brugia malayi Inositol-1 0.0036 0.0258 0.047
Loa Loa (eye worm) hypothetical protein 0.0062 0.0527 0.096
Schistosoma mansoni jumonji domain containing protein 0.0074 0.0648 0.1545
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0318 0.3203 0.641
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0156 0.1502 0.3584
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0028 0.0166 0.0224
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0132 0.366
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0062 0.0527 0.4116
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0042 0.0312 0.5906
Brugia malayi Thioredoxin family protein 0.0413 0.4189 0.7648
Echinococcus multilocularis dna polymerase kappa 0.0038 0.0277 0.0428
Mycobacterium tuberculosis Conserved hypothetical protein 0.0038 0.0277 0.0561
Mycobacterium tuberculosis Conserved protein 0.0413 0.4189 1
Brugia malayi Muscleblind-like protein 0.0147 0.1414 0.2582
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0134 0.1278 1
Schistosoma mansoni lamin 0.0057 0.0474 0.1129
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0259 0.0482
Mycobacterium tuberculosis Hypothetical protein 0.0413 0.4189 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.019 0.1866 0.3354
Mycobacterium ulcerans hypothetical protein 0.0039 0.0282 0.0669
Onchocerca volvulus 0.0489 0.4985 0.4975
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0174 0.135
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0259 0.0482
Schistosoma mansoni aldehyde dehydrogenase 0.0134 0.1278 0.3049
Schistosoma mansoni hypothetical protein 0.0067 0.0581 0.1384
Loa Loa (eye worm) hypothetical protein 0.0099 0.0907 0.1653
Toxoplasma gondii NADPH-glutathione reductase 0.0016 0.0044 0.0334
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0091 0.0087
Echinococcus granulosus lamin dm0 0.0057 0.0474 0.0792
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0105 0.0973 0.2242
Echinococcus granulosus neutral alpha glucosidase AB 0.0037 0.0259 0.0396
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.0044 0.0081
Loa Loa (eye worm) PHD-finger family protein 0.0028 0.0174 0.0315
Loa Loa (eye worm) hypothetical protein 0.0039 0.0282 0.0512
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0031 0.0203 0.0371
Plasmodium vivax thioredoxin reductase, putative 0.0046 0.0358 0.6785
Echinococcus multilocularis jumonji domain containing protein 0.0039 0.029 0.0452
Loa Loa (eye worm) hypothetical protein 0.0039 0.0282 0.0512
Onchocerca volvulus 0.0095 0.0872 0.0854
Giardia lamblia Hypothetical protein 0.0413 0.4189 1
Trypanosoma brucei unspecified product 0.0026 0.0153 0.4243
Loa Loa (eye worm) hypothetical protein 0.0027 0.0155 0.028
Mycobacterium leprae Probable lipase LipE 0.0039 0.0282 0.0161
Loa Loa (eye worm) hypothetical protein 0.0039 0.0282 0.0512
Brugia malayi Glycosyl hydrolases family 31 protein 0.0037 0.0259 0.0473
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0253 0.7064
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0134 0.1278 0.2271
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0091 0.0144
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0031 0.0203 0.0293
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0036 0.0253 0.1973
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0282 0.0669
Loa Loa (eye worm) hypothetical protein 0.0014 0.002 0.0033
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0099 0.0907 0.1653
Echinococcus multilocularis PHD finger protein rhinoceros 0.0028 0.0174 0.0239
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0044 0.0334
Echinococcus multilocularis lysosomal alpha glucosidase 0.0165 0.1597 0.2858
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0016 0.0044 0.0334
Loa Loa (eye worm) hypothetical protein 0.0027 0.0155 0.028
Onchocerca volvulus 0.0039 0.0282 0.0263
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0258 0.0747
Mycobacterium leprae Conserved hypothetical protein 0.0413 0.4189 1
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0258 0.2006
Schistosoma mansoni DNA polymerase eta 0.0038 0.0277 0.0657
Onchocerca volvulus 0.0062 0.0527 0.0508
Loa Loa (eye worm) hypothetical protein 0.0057 0.0474 0.0864
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0277 0.7714
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0258 0.0479
Brugia malayi beta-lactamase family protein 0.0039 0.0282 0.0515
Trichomonas vaginalis peptide N-glycanase, putative 0.0413 0.4189 0.8396
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0117 0.1096 0.2211
Loa Loa (eye worm) hypothetical protein 0.0024 0.0132 0.0238
Leishmania major hypothetical protein, conserved 0.0024 0.0132 0.1022
Echinococcus granulosus muscleblind protein 0.0147 0.1414 0.2522
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0253 0.0385
Schistosoma mansoni hypothetical protein 0.0399 0.4044 0.9654
Trypanosoma brucei glucosidase, putative 0.0037 0.0259 0.7227
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0277 0.7714
Onchocerca volvulus 0.0039 0.0282 0.0263
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0091 0.0167
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0258 0.0479
Mycobacterium tuberculosis Long conserved protein 0.0413 0.4189 1
Trichomonas vaginalis esterase, putative 0.0039 0.0282 0.0528
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0105 0.0973 0.2242
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0044 0.1197
Brugia malayi PHD-finger family protein 0.0028 0.0174 0.0318
Trichomonas vaginalis bromodomain-containing protein, putative 0.0042 0.0312 0.0588
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0031 0.0203 0.0293
Onchocerca volvulus 0.0109 0.102 0.1002
Onchocerca volvulus 0.0057 0.0474 0.0455
Brugia malayi Thioredoxin reductase 0.0046 0.0358 0.0654
Loa Loa (eye worm) hypothetical protein 0.0036 0.0253 0.046
Toxoplasma gondii LsmAD domain-containing protein 0.0024 0.0132 0.1022
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0282 0.0528
Loa Loa (eye worm) hypothetical protein 0.0039 0.0282 0.0512
Toxoplasma gondii histone lysine methyltransferase SET1 0.0059 0.0492 0.384
Giardia lamblia Fructose-bisphosphate aldolase 0.0318 0.3203 0.7646
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0318 0.3203 0.641
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0044 0.0334
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.0153 0.4243
Brugia malayi beta-lactamase family protein 0.0039 0.0282 0.0515
Loa Loa (eye worm) hypothetical protein 0.0147 0.1414 0.258
Loa Loa (eye worm) hypothetical protein 0.0536 0.5477 1
Leishmania major trypanothione reductase 0.0046 0.0358 0.2793
Plasmodium falciparum phd finger protein, putative 0.0028 0.0174 0.4834
Mycobacterium ulcerans beta-lactamase 0.0039 0.0282 0.0669
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.019 0.1866 0.4453
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0105 0.0973 0.2242
Echinococcus granulosus peregrin 0.0032 0.021 0.0305
Giardia lamblia PHD finger protein 15 0.0028 0.0174 0.0412
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.0277 0.7714
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0044 0.1197
Echinococcus multilocularis GPCR, family 2 0.0031 0.0203 0.0293
Brugia malayi hypothetical protein 0.0536 0.5477 1
Trichomonas vaginalis mercuric reductase, putative 0.0016 0.0044 0.0049
Mycobacterium leprae conserved hypothetical protein 0.0039 0.0282 0.0161
Echinococcus multilocularis musashi 0.0057 0.0474 0.0792
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0156 0.1502 0.3518
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0016 0.0044 0.5
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0091 0.0114
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.0277 0.7714
Leishmania major glycosyl hydrolase-like protein 0.0014 0.002 0.0143
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0318 0.3203 0.641
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0038 0.0277 0.0502
Echinococcus granulosus dna polymerase kappa 0.0038 0.0277 0.0428
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0318 0.3203 1
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0109 0.102 0.1862
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0016 0.0044 0.1197
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0036 0.0253 0.0602
Echinococcus multilocularis thioredoxin glutathione reductase 0.0046 0.0358 0.0578
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0039 0.0282 0.0573
Echinococcus granulosus GPCR family 2 0.0031 0.0203 0.0293
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0039 0.0282 0.0512
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0042 0.0312 0.2431
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0016 0.0044 0.0102
Loa Loa (eye worm) intermediate filament protein 0.0057 0.0474 0.0864
Toxoplasma gondii thioredoxin reductase 0.0046 0.0358 0.2793
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.0259 0.0752
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0044 0.1197
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0253 0.047
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.0527 0.1255
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.0527 0.1255
Brugia malayi intermediate filament protein 0.0057 0.0474 0.0866
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0253 0.047
Loa Loa (eye worm) latrophilin receptor protein 2 0.0031 0.0203 0.0369
Loa Loa (eye worm) hypothetical protein 0.0049 0.0386 0.0703
Brugia malayi latrophilin 2 splice variant baaae 0.0067 0.0581 0.1061
Mycobacterium tuberculosis Conserved hypothetical protein 0.0413 0.4189 1
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0038 0.0277 0.0657
Echinococcus multilocularis dna polymerase eta 0.0038 0.0277 0.0428
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0099 0.0907 0.1656
Mycobacterium tuberculosis Probable lipase LipD 0.0039 0.0282 0.0573
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0091 0.1711
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0132 0.366
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0258 0.0612
Trypanosoma brucei DNA polymerase IV, putative 0.0038 0.0277 0.7714
Trichomonas vaginalis sucrase-isomaltase, putative 0.0037 0.0259 0.0482
Trichomonas vaginalis DNA polymerase eta, putative 0.0038 0.0277 0.0517
Toxoplasma gondii ABC1 family protein 0.0039 0.0282 0.2196
Trypanosoma cruzi trypanothione reductase, putative 0.0046 0.0358 1
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0038 0.0277 0.0561
Loa Loa (eye worm) hypothetical protein 0.0056 0.0463 0.0844
Schistosoma mansoni survival motor neuron protein 0.0109 0.102 0.2432
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0258 0.0479
Leishmania major alpha glucosidase II subunit, putative 0.0037 0.0259 0.2019
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0091 0.2521
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0247 0.2459 0.5827
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0282 0.7861
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0038 0.0277 0.0428
Echinococcus granulosus tumor protein p63 0.0333 0.3353 0.609
Brugia malayi hypothetical protein 0.0016 0.0042 0.0076
Echinococcus multilocularis neutral alpha glucosidase AB 0.0037 0.0259 0.0396
Schistosoma mansoni ap endonuclease 0.002 0.0091 0.0215
Loa Loa (eye worm) hypothetical protein 0.0039 0.0282 0.0512
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0016 0.0044 0.0102
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0091 0.2521
Trypanosoma brucei DNA polymerase eta, putative 0.0038 0.0277 0.7714
Trypanosoma cruzi trypanothione reductase, putative 0.0016 0.0044 0.1197
Echinococcus granulosus histone acetyltransferase KAT2B 0.0137 0.1313 0.2335
Echinococcus granulosus survival motor neuron protein 1 0.0536 0.5477 1
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0036 0.0253 0.0463
Echinococcus multilocularis muscleblind protein 0.0147 0.1414 0.2522
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0174 0.135
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0016 0.0044 0.0812
Leishmania major DNA polymerase eta, putative 0.0038 0.0277 0.2155
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0253 0.0385
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0091 0.0164
Schistosoma mansoni cpg binding protein 0.0028 0.017 0.0403
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0016 0.0044 0.0334
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0016 0.0044 0.1197
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0141 0.1354 0.323
Schistosoma mansoni hypothetical protein 0.0031 0.0203 0.0482
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0282 0.0528
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0091 0.0087
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0031 0.0197 0.0358
Plasmodium vivax SET domain protein, putative 0.0062 0.0527 1
Loa Loa (eye worm) hypothetical protein 0.0067 0.0581 0.1059
Brugia malayi Glycosyl hydrolases family 31 protein 0.0165 0.1597 0.2916
Mycobacterium ulcerans transglutaminase family protein 0.0413 0.4189 1
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0259 0.0482
Mycobacterium ulcerans hypothetical protein 0.0413 0.4189 1
Brugia malayi F/Y-rich N-terminus family protein 0.002 0.0088 0.016
Onchocerca volvulus Alhambra homolog 0.0028 0.0174 0.0154
Brugia malayi hypothetical protein 0.0024 0.0132 0.0241
Giardia lamblia DINP protein human, muc B family 0.0038 0.0277 0.0657
Brugia malayi Intermediate filament tail domain containing protein 0.0057 0.0474 0.0866
Echinococcus multilocularis lysosomal alpha glucosidase 0.0165 0.1597 0.2858
Brugia malayi beta-lactamase 0.0039 0.0282 0.0515
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0093 0.0848 0.1479
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.019 0.1866 0.3354
Brugia malayi CXXC zinc finger family protein 0.0028 0.017 0.0311
Schistosoma mansoni cpg binding protein 0.003 0.0187 0.0443
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.0091 0.0215
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0028 0.0166 0.0224
Mycobacterium tuberculosis Conserved protein 0.0039 0.0282 0.0573
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0259 0.0482
Echinococcus granulosus histone lysine methyltransferase setb 0.0062 0.0527 0.0889
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.0218 0.0419
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.0153 0.4243
Schistosoma mansoni inositol monophosphatase 0.0036 0.0258 0.0612
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.0527 0.1255
Brugia malayi glutathione reductase 0.0046 0.0358 0.0654
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0318 0.3203 1
Schistosoma mansoni ap endonuclease 0.002 0.0091 0.0215
Plasmodium falciparum glutathione reductase 0.0046 0.0358 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0277 0.7714
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0132 0.366
Echinococcus multilocularis lamin dm0 0.0057 0.0474 0.0792
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0042 0.0312 0.2431
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0044 0.1197
Schistosoma mansoni alpha-glucosidase 0.0142 0.1357 0.3238
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0318 0.3203 0.641
Trypanosoma brucei DNA polymerase IV, putative 0.0038 0.0277 0.7714
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0038 0.0277 0.2155
Mycobacterium tuberculosis Probable hydrolase 0.0039 0.0282 0.0573
Mycobacterium tuberculosis Probable dehydrogenase 0.0105 0.0973 0.2242
Echinococcus granulosus jumonji domain containing protein 0.0039 0.029 0.0452
Loa Loa (eye worm) hypothetical protein 0.0028 0.0174 0.0315
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0016 0.0044 0.0102
Echinococcus multilocularis beta LACTamase domain containing family member 0.0039 0.0282 0.0437
Plasmodium vivax hypothetical protein, conserved 0.0039 0.0282 0.5334
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0057 0.0474 0.0864
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0277 0.7714
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0277 0.7714
Onchocerca volvulus 0.0028 0.017 0.0151
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0036 0.0253 0.0602
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0062 0.0527 0.0889
Giardia lamblia Histone acetyltransferase GCN5 0.0038 0.0276 0.0655
Toxoplasma gondii exonuclease III APE 0.002 0.0091 0.0704
Schistosoma mansoni alpha glucosidase 0.0037 0.0259 0.0615
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.0277 0.7714
Plasmodium falciparum glutathione reductase 0.0016 0.0044 0.1197
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0059 0.0497 0.0833
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.0153 0.4243
Echinococcus granulosus intermediate filament protein 0.0057 0.0474 0.0792
Brugia malayi Glycosyl hydrolases family 31 protein 0.0014 0.002 0.0036
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0044 0.1197
Loa Loa (eye worm) hypothetical protein 0.0038 0.0277 0.0502
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0253 0.0385
Plasmodium falciparum histone acetyltransferase GCN5 0.0038 0.0276 0.769
Mycobacterium tuberculosis Probable oxidoreductase 0.0117 0.1096 0.2537
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0277 0.7714
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.018 0.1761 0.3216
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0259 0.0482
Echinococcus multilocularis geminin 0.0349 0.352 0.6398
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0258 0.7182
Onchocerca volvulus 0.0049 0.0386 0.0367
Loa Loa (eye worm) MH2 domain-containing protein 0.0135 0.1291 0.2355
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.0522 0.1243
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0091 0.0704
Giardia lamblia NADH oxidase lateral transfer candidate 0.0016 0.0044 0.0102
Onchocerca volvulus 0.0039 0.0282 0.0263
Leishmania major hypothetical protein, conserved 0.0039 0.0282 0.2196
Echinococcus granulosus lamin 0.0057 0.0474 0.0792
Schistosoma mansoni hypothetical protein 0.0109 0.102 0.2432
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.019 0.1866 0.3354
Schistosoma mansoni hypothetical protein 0.0413 0.4189 1
Schistosoma mansoni jumonji/arid domain-containing protein 0.0036 0.0253 0.06
Echinococcus granulosus dna polymerase eta 0.0038 0.0277 0.0428
Brugia malayi ImpB/MucB/SamB family protein 0.0038 0.0277 0.0505
Echinococcus multilocularis tumor protein p63 0.0333 0.3353 0.609
Schistosoma mansoni inositol monophosphatase 0.0036 0.0258 0.0612
Loa Loa (eye worm) hypothetical protein 0.0039 0.0282 0.0512
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0277 0.7714
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.002 0.0091 0.0215
Loa Loa (eye worm) acetyltransferase 0.0141 0.1354 0.247
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0318 0.3203 0.641
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0258 0.7182
Schistosoma mansoni hypothetical protein 0.0031 0.0203 0.0482
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0258 0.0393
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.019 0.1866 0.3407
Plasmodium vivax ataxin-2 like protein, putative 0.0024 0.0132 0.2484
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.019 0.1866 0.4453
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0259 0.7227
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0062 0.0527 0.1255
Leishmania major DNA polymerase kappa, putative 0.0038 0.0277 0.2155
Echinococcus granulosus ubiquitin specific protease 41 0.0036 0.0253 0.0385
Mycobacterium ulcerans aldehyde dehydrogenase 0.0134 0.1278 0.3049
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0018 0.0071 0.0166
Schistosoma mansoni intermediate filament proteins 0.0057 0.0474 0.1129
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0117 0.1096 0.2537
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0132 0.366
Schistosoma mansoni aldehyde dehydrogenase 0.0134 0.1278 0.3049
Brugia malayi Pre-SET motif family protein 0.0062 0.0527 0.0962
Loa Loa (eye worm) thioredoxin reductase 0.0046 0.0358 0.0651
Mycobacterium tuberculosis Conserved protein 0.0039 0.0282 0.0573
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0259 0.0482
Loa Loa (eye worm) transcription factor SMAD2 0.0135 0.1291 0.2355

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 18.526 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 22.3872 uM PubChem BioAssay. qHTS for Inhibitors of WRN Helicase. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 25.1189 uM PubChem BioAssay. qHTS Assay for Activators of ClpP. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 35.4813 uM PubChem BioAssay. qHTS of TDP-43 Inhibitors. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference
Potency (functional) = 100 um PUBCHEM_BIOASSAY: qHTS Inhibitors of AmpC Beta-Lactamase (assay with detergent). (Class of assay: confirmatory) [Related pubchem assays: 1002 (Confirmation Concentration-Response Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent)), 585 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent) - a screen old NIH MLSMR collection), 584 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent) - a screen of the old NIH MLSMR collection), 1003 (Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent))] ChEMBL. No reference
Potency (functional) 112.2018 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Rango (Ran-regulated importin-beta cargo) - Importin beta complex formation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID540273] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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