Detailed information for compound 1250637

Basic information

Technical information
  • TDR Targets ID: 1250637
  • Name: [4-(5-tert-butyl-2-methyl-3-phenylpyrazolo[5, 1-b]pyrimidin-7-yl)piperazin-1-yl]-furan-2-yl methanone
  • MW: 443.541 | Formula: C26H29N5O2
  • H donors: 0 H acceptors: 3 LogP: 4.84 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1nn2c(c1c1ccccc1)nc(cc2N1CCN(CC1)C(=O)c1ccco1)C(C)(C)C
  • InChi: 1S/C26H29N5O2/c1-18-23(19-9-6-5-7-10-19)24-27-21(26(2,3)4)17-22(31(24)28-18)29-12-14-30(15-13-29)25(32)20-11-8-16-33-20/h5-11,16-17H,12-15H2,1-4H3
  • InChiKey: GCIHZGVTMHOIDZ-UHFFFAOYSA-N  


Substructure search Similarity search

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Synonyms

  • [4-(5-tert-butyl-2-methyl-3-phenyl-pyrazolo[5,1-b]pyrimidin-7-yl)piperazin-1-yl]-(2-furyl)methanone
  • [4-(5-tert-butyl-2-methyl-3-phenyl-7-pyrazolo[5,1-b]pyrimidinyl)-1-piperazinyl]-(2-furyl)methanone
  • [4-(5-tert-butyl-2-methyl-3-phenyl-pyrazolo[5,1-b]pyrimidin-7-yl)piperazin-1-yl]-furan-2-yl-methanone
  • MLS000042271
  • SMR000046975
  • STOCK5S-19789

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens ATP-binding cassette, sub-family B (MDR/TAP), member 1 Starlite/ChEMBL No references
Trypanosoma cruzi cysteine peptidase, putative Starlite/ChEMBL No references
Homo sapiens aldehyde dehydrogenase 1 family, member A1 Starlite/ChEMBL No references
Homo sapiens hydroxyprostaglandin dehydrogenase 15-(NAD) Starlite/ChEMBL No references
Influenza A virus Nonstructural protein 1 Starlite/ChEMBL No references
Streptococcus pyogenes serotype M1 Streptokinase A Starlite/ChEMBL No references
Homo sapiens neuropeptide S receptor 1 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium knowlesi basic transcription factor 3b, putative Get druggable targets OG5_127333 All targets in OG5_127333
Entamoeba histolytica hypothetical protein Get druggable targets OG5_127333 All targets in OG5_127333
Brugia malayi cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania braziliensis cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis neuropeptide receptor A26 Get druggable targets OG5_136011 All targets in OG5_136011
Echinococcus granulosus cathepsin L cysteine proteinase Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva transcription factor BTF3, putative Get druggable targets OG5_127333 All targets in OG5_127333
Trichomonas vaginalis ATP-binding cassette transporter, putative Get druggable targets OG5_126596 All targets in OG5_126596
Candida albicans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Onchocerca volvulus Cathepsin F homolog Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis ATP-binding cassette transporter, putative Get druggable targets OG5_126596 All targets in OG5_126596
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Entamoeba histolytica P-glyco protein 6, putative Get druggable targets OG5_126596 All targets in OG5_126596
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 Get druggable targets OG5_126596 All targets in OG5_126596
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus multidrug resistance protein 1 Get druggable targets OG5_126596 All targets in OG5_126596
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) Get druggable targets OG5_126596 All targets in OG5_126596
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 Get druggable targets OG5_126596 All targets in OG5_126596
Echinococcus granulosus multidrug resistance protein 1 Get druggable targets OG5_126596 All targets in OG5_126596
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium falciparum cysteine proteinase falcipain 2a Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium berghei transcription factor 3b, putative Get druggable targets OG5_127333 All targets in OG5_127333
Leishmania infantum aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus granulosus multidrug resistance protein 1 Get druggable targets OG5_126596 All targets in OG5_126596
Trichomonas vaginalis ATP-binding cassette transporter, putative Get druggable targets OG5_126596 All targets in OG5_126596
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) ICD-1 protein Get druggable targets OG5_127333 All targets in OG5_127333
Schistosoma mansoni cathepsin F (C01 family) Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) fibroinase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Candida albicans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma mansoni multidrug resistance protein Get druggable targets OG5_126596 All targets in OG5_126596
Neospora caninum Cathepsin L, related Get druggable targets OG5_126607 All targets in OG5_126607
Toxoplasma gondii NAC domain-containing protein Get druggable targets OG5_127333 All targets in OG5_127333
Trypanosoma brucei gambiense cysteine peptidase precursor,cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania infantum basic transcription factor 3a, putative Get druggable targets OG5_127333 All targets in OG5_127333
Trypanosoma brucei gambiense cysteine peptidase precursor,cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus multidrug resistance protein 1 Get druggable targets OG5_126596 All targets in OG5_126596
Brugia malayi multidrug resistance protein 3 Get druggable targets OG5_126596 All targets in OG5_126596
Entamoeba histolytica cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum Multidrug resistance protein 3, putative Get druggable targets OG5_126596 All targets in OG5_126596
Cryptosporidium hominis cryptopain precursor Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium berghei multidrug resistance protein 1, putative Get druggable targets OG5_126596 All targets in OG5_126596
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi ABC transporter family protein Get druggable targets OG5_126596 All targets in OG5_126596
Schistosoma japonicum Multidrug resistance protein 1, putative Get druggable targets OG5_126596 All targets in OG5_126596
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP Get druggable targets OG5_126596 All targets in OG5_126596
Schistosoma japonicum Retinal dehydrogenase 1, putative Get druggable targets OG5_126638 All targets in OG5_126638
Neospora caninum hypothetical protein Get druggable targets OG5_127333 All targets in OG5_127333
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania braziliensis cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium knowlesi knowpain-4 Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis multidrug resistance protein 1, 2, putative Get druggable targets OG5_126596 All targets in OG5_126596
Entamoeba histolytica P-glycoprotein-5 Get druggable targets OG5_126596 All targets in OG5_126596
Theileria parva cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania infantum ATP-binding cassette protein subfamily B, member 2, putative Get druggable targets OG5_126596 All targets in OG5_126596
Plasmodium yoelii berghepain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania donovani aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania donovani p-glycoprotein Get druggable targets OG5_126596 All targets in OG5_126596
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania infantum cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum Multidrug resistance protein 2, putative Get druggable targets OG5_126596 All targets in OG5_126596
Cryptosporidium parvum ATP-binding cassette transporter Get druggable targets OG5_126596 All targets in OG5_126596
Theileria parva cysteine protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum Bile salt export pump, putative Get druggable targets OG5_126596 All targets in OG5_126596
Leishmania braziliensis basic transcription factor 3a, putative Get druggable targets OG5_127333 All targets in OG5_127333
Plasmodium falciparum cysteine proteinase falcipain 2b Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126596 All targets in OG5_126596
Cryptosporidium parvum BTF domain, basal transcription factor Get druggable targets OG5_127333 All targets in OG5_127333
Trypanosoma brucei transcription factor BTF3, putative Get druggable targets OG5_127333 All targets in OG5_127333
Schistosoma japonicum ko:K00128 aldehyde dehydrogenase (NAD+) [EC1.2.1.3], putative Get druggable targets OG5_126638 All targets in OG5_126638
Neospora caninum hypothetical protein Get druggable targets OG5_126596 All targets in OG5_126596
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma japonicum IPR000276,Rhodopsin-like GPCR superfamily,domain-containing Get druggable targets OG5_136011 All targets in OG5_136011
Echinococcus multilocularis multidrug resistance protein 1 Get druggable targets OG5_126596 All targets in OG5_126596
Plasmodium knowlesi multidrug resistance protein 1, putative Get druggable targets OG5_126596 All targets in OG5_126596
Echinococcus multilocularis cathepsin l cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Mycobacterium tuberculosis Probable aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma japonicum ko:K01373 cathepsin F [EC3.4.22.41], putative Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana cysteine peptidase A (CBA) Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania donovani transcription factor btf3, putative Get druggable targets OG5_127333 All targets in OG5_127333
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei gambiense cysteine peptidase precursor,cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium knowlesi knowpain-3 Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum Multidrug resistance protein 1, putative Get druggable targets OG5_126596 All targets in OG5_126596
Entamoeba histolytica cysteine protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium vivax basic transcription factor 3b, putative Get druggable targets OG5_127333 All targets in OG5_127333
Babesia bovis NAC domain containing protein Get druggable targets OG5_127333 All targets in OG5_127333
Schistosoma mansoni aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Cryptosporidium parvum cryptopain - cysteine proteinase secreted, possible transmembrane domain near N-terminus Get druggable targets OG5_126607 All targets in OG5_126607
Toxoplasma gondii cathepsin CPL Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis ATP-binding cassette transporter, putative Get druggable targets OG5_126596 All targets in OG5_126596
Trichomonas vaginalis abcb9, putative Get druggable targets OG5_126596 All targets in OG5_126596
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni cathepsin F (C01 family) Get druggable targets OG5_126607 All targets in OG5_126607
Cryptosporidium hominis NAC domain protein Get druggable targets OG5_127333 All targets in OG5_127333
Echinococcus multilocularis cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni smdr2 Get druggable targets OG5_126596 All targets in OG5_126596
Trichomonas vaginalis multidrug resistance protein 1, 2, putative Get druggable targets OG5_126596 All targets in OG5_126596
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative Get druggable targets OG5_126596 All targets in OG5_126596
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126596 All targets in OG5_126596
Leishmania major basic transcription factor 3a, putative Get druggable targets OG5_127333 All targets in OG5_127333
Schistosoma mansoni transcription factor btf3 Get druggable targets OG5_127333 All targets in OG5_127333
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein Get druggable targets OG5_126596 All targets in OG5_126596
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Neospora caninum ATP-binding cassette, sub-family B (MDR/TAP), member 4, related Get druggable targets OG5_126596 All targets in OG5_126596
Brugia malayi Papain family cysteine protease containing protein Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative Get druggable targets OG5_126596 All targets in OG5_126596
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) Get druggable targets OG5_126596 All targets in OG5_126596
Trichomonas vaginalis multidrug resistance protein 1, 2, putative Get druggable targets OG5_126596 All targets in OG5_126596
Leishmania infantum cysteine peptidase A (CPA) Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania braziliensis cysteine peptidase A (CPA) Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Entamoeba histolytica cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium falciparum cysteine proteinase falcipain 3 Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative Get druggable targets OG5_126596 All targets in OG5_126596
Candida albicans Mitochondrial aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium yoelii basic transcription factor 3, putative Get druggable targets OG5_127333 All targets in OG5_127333
Trypanosoma cruzi transcription factor btf3, putative Get druggable targets OG5_127333 All targets in OG5_127333
Leishmania mexicana cathepsin L-like protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis ABC transporter, half transporter, putative Get druggable targets OG5_126596 All targets in OG5_126596
Schistosoma japonicum ko:K01527 nascent polypeptide-associated complex subunit beta, putative Get druggable targets OG5_127333 All targets in OG5_127333
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Candida albicans similar to S. cerevisiae GAL4 enhancer protein EGD1 (YPL037C) subunit alpha of the nascent polypeptide-associated chaperone comp Get druggable targets OG5_127333 All targets in OG5_127333
Trypanosoma brucei gambiense nascent polypeptide associated complex alpha subunit, putative Get druggable targets OG5_127333 All targets in OG5_127333
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Candida albicans similar to S. cerevisiae GAL4 enhancer protein EGD1 (YPL037C) subunit alpha of the nascent polypeptide-associated chaperone comp Get druggable targets OG5_127333 All targets in OG5_127333
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) Get druggable targets OG5_126596 All targets in OG5_126596
Leishmania mexicana aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP Get druggable targets OG5_126596 All targets in OG5_126596
Trichomonas vaginalis ATP-binding cassette transporter, putative Get druggable targets OG5_126596 All targets in OG5_126596
Plasmodium vivax multidrug resistance protein 1, putative Get druggable targets OG5_126596 All targets in OG5_126596
Trichomonas vaginalis multidrug resistance protein 1, 2, putative Get druggable targets OG5_126596 All targets in OG5_126596
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) Get druggable targets OG5_126596 All targets in OG5_126596
Echinococcus granulosus aldehyde dehydrogenase mitochondrial Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Entamoeba histolytica P-glycoprotein-2 Get druggable targets OG5_126596 All targets in OG5_126596
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania infantum p-glycoprotein Get druggable targets OG5_126596 All targets in OG5_126596
Leishmania major p-glycoprotein Get druggable targets OG5_126596 All targets in OG5_126596
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative Get druggable targets OG5_126596 All targets in OG5_126596
Trypanosoma cruzi transcription factor btf3, putative Get druggable targets OG5_127333 All targets in OG5_127333
Entamoeba histolytica transcription factor BTF3, putative Get druggable targets OG5_127333 All targets in OG5_127333
Chlamydia trachomatis ABC transporter ATP binding protein/permease Get druggable targets OG5_126596 All targets in OG5_126596
Leishmania donovani cysteine peptidase A (CBA) Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania donovani ATP-binding cassette protein subfamily B, member 2, putative Get druggable targets OG5_126596 All targets in OG5_126596
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP Get druggable targets OG5_126596 All targets in OG5_126596
Theileria parva cysteine protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum Multidrug resistance protein 1, putative Get druggable targets OG5_126596 All targets in OG5_126596
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Trypanosoma cruzi cysteine peptidase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum Cathepsin L-like proteinase precursor, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative Get druggable targets OG5_126596 All targets in OG5_126596
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump Get druggable targets OG5_126596 All targets in OG5_126596
Echinococcus granulosus cathepsin l cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis multidrug resistance protein 1, 2, putative Get druggable targets OG5_126596 All targets in OG5_126596
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus multilocularis neuropeptide s receptor Get druggable targets OG5_136011 All targets in OG5_136011
Schistosoma mansoni aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma mansoni multidrug resistance protein Get druggable targets OG5_126596 All targets in OG5_126596
Echinococcus multilocularis multidrug resistance protein 1 Get druggable targets OG5_126596 All targets in OG5_126596
Echinococcus granulosus 5'partial|ATP binding cassette sub family B Get druggable targets OG5_126596 All targets in OG5_126596
Brugia malayi beta-NAC-like protein Get druggable targets OG5_127333 All targets in OG5_127333
Brugia malayi Cathepsin L-like cysteine proteinase Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus cathepsin l1 Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis conserved hypothetical protein Get druggable targets OG5_127333 All targets in OG5_127333
Schistosoma japonicum expressed protein Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus transcription factor btf3 Get druggable targets OG5_127333 All targets in OG5_127333
Echinococcus granulosus neuropeptide receptor A26 Get druggable targets OG5_136011 All targets in OG5_136011
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cathepsin L cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Candida albicans potential ABC transporter similar to S. cerevisiae STE6 (YKL209C) involved in peptide pheromone export Get druggable targets OG5_126596 All targets in OG5_126596
Theileria parva cysteine protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Entamoeba histolytica cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana cathepsin L-like protease, putative Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Cathepsin L homolog Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis abcb9, putative Get druggable targets OG5_126596 All targets in OG5_126596
Entamoeba histolytica P-glycoprotein-1 Get druggable targets OG5_126596 All targets in OG5_126596
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Entamoeba histolytica P-glycoprotein-2, putative Get druggable targets OG5_126596 All targets in OG5_126596
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126596 All targets in OG5_126596
Trichomonas vaginalis ABC transporter, putative Get druggable targets OG5_126596 All targets in OG5_126596
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Brugia malayi Cathepsin L-like precursor Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126607 All targets in OG5_126607
Entamoeba histolytica P-glycoprotein-2 Get druggable targets OG5_126596 All targets in OG5_126596
Schistosoma japonicum ATP-binding cassette sub-family B member 5, putative Get druggable targets OG5_126596 All targets in OG5_126596
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania infantum cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Plasmodium yoelii multidrug resistance protein Get druggable targets OG5_126596 All targets in OG5_126596
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cysteine peptidase A (CPA) Get druggable targets OG5_126607 All targets in OG5_126607
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) multidrug resistance protein 3 Get druggable targets OG5_126596 All targets in OG5_126596
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cysteine peptidase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) papain family cysteine protease containing protein Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana basic transcription factor 3a, putative Get druggable targets OG5_127333 All targets in OG5_127333
Schistosoma japonicum Multidrug resistance protein 3, putative Get druggable targets OG5_126596 All targets in OG5_126596
Toxoplasma gondii aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative Get druggable targets OG5_126596 All targets in OG5_126596
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma cruzi cruzipain precursor, putative Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis ATP binding cassette sub family B Get druggable targets OG5_126596 All targets in OG5_126596
Plasmodium knowlesi knowpain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP Get druggable targets OG5_126596 All targets in OG5_126596
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Candida albicans Mitochondrial aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania braziliensis aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania braziliensis cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis conserved hypothetical protein Get druggable targets OG5_127333 All targets in OG5_127333
Plasmodium berghei berghepain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania major cathepsin L-like protease Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Neospora caninum hypothetical protein Get druggable targets OG5_126638 All targets in OG5_126638
Onchocerca volvulus Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis abcb9, putative Get druggable targets OG5_126596 All targets in OG5_126596
Schistosoma mansoni multidrug resistance protein Get druggable targets OG5_126596 All targets in OG5_126596
Schistosoma japonicum Multidrug resistance protein 1, putative Get druggable targets OG5_126596 All targets in OG5_126596
Leishmania mexicana p-glycoprotein Get druggable targets OG5_126596 All targets in OG5_126596
Schistosoma japonicum Aldehyde dehydrogenase X, mitochondrial precursor, putative Get druggable targets OG5_126638 All targets in OG5_126638
Entamoeba histolytica P-glycoprotein 5, putative Get druggable targets OG5_126596 All targets in OG5_126596
Echinococcus multilocularis transcription factor btf3 Get druggable targets OG5_127333 All targets in OG5_127333
Echinococcus granulosus multidrug resistance protein 1 Get druggable targets OG5_126596 All targets in OG5_126596
Leishmania mexicana Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma mansoni cathepsin F (C01 family) Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum ko:K05659 ATP-binding cassette, subfamily B (MDR/TAP), member 4, putative Get druggable targets OG5_126596 All targets in OG5_126596
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative Get druggable targets OG5_126596 All targets in OG5_126596
Trichomonas vaginalis conserved hypothetical protein Get druggable targets OG5_127333 All targets in OG5_127333
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative Get druggable targets OG5_126596 All targets in OG5_126596
Echinococcus granulosus neuropeptide s receptor Get druggable targets OG5_136011 All targets in OG5_136011
Trichomonas vaginalis ABC transporter, half transporter, putative Get druggable targets OG5_126596 All targets in OG5_126596
Trichomonas vaginalis multidrug resistance protein 1, 2, putative Get druggable targets OG5_126596 All targets in OG5_126596
Loa Loa (eye worm) ctsf protein Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126596 All targets in OG5_126596
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis ABC transporter, putative Get druggable targets OG5_126596 All targets in OG5_126596
Plasmodium vivax vivapain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis taga, putative Get druggable targets OG5_126596 All targets in OG5_126596
Trichomonas vaginalis ATP-binding cassette transporter, putative Get druggable targets OG5_126596 All targets in OG5_126596
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative Get druggable targets OG5_126596 All targets in OG5_126596
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) Get druggable targets OG5_126596 All targets in OG5_126596
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis multidrug resistance protein 1 Get druggable targets OG5_126596 All targets in OG5_126596
Trichomonas vaginalis multidrug resistance protein 1, 2, putative Get druggable targets OG5_126596 All targets in OG5_126596
Plasmodium vivax vivapain-2 Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine proteinase, putative Get druggable targets OG5_126607 All targets in OG5_126607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Cryptosporidium hominis ATP-binding cassette protein 3 Get druggable targets OG5_126596 All targets in OG5_126596
Echinococcus granulosus cathepsin l1 Get druggable targets OG5_126607 All targets in OG5_126607
Leishmania mexicana p-glycoprotein-like protein,ABC transporter-like protein,multidrug resistance protein-like protein Get druggable targets OG5_126596 All targets in OG5_126596
Trypanosoma congolense cysteine peptidase, Clan CA, family C1, Cathepsin L-like Get druggable targets OG5_126607 All targets in OG5_126607
Echinococcus multilocularis cathepsin L cysteine protease Get druggable targets OG5_126607 All targets in OG5_126607
Schistosoma japonicum Aldehyde dehydrogenase, mitochondrial precursor, putative Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus multilocularis cathepsin l cysteine peptidase Get druggable targets OG5_126607 All targets in OG5_126607
Theileria parva cysteine proteinase Get druggable targets OG5_126607 All targets in OG5_126607
Onchocerca volvulus Cathepsin L homolog Get druggable targets OG5_126607 All targets in OG5_126607
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126607 All targets in OG5_126607
Trichomonas vaginalis ABC transporter, putative Get druggable targets OG5_126596 All targets in OG5_126596
Leishmania braziliensis p-glycoprotein-like protein,ABC transporter-like protein,multidrug resistance protein-like protein Get druggable targets OG5_126596 All targets in OG5_126596
Plasmodium falciparum multidrug resistance protein 1 Get druggable targets OG5_126596 All targets in OG5_126596
Plasmodium falciparum basic transcription factor 3b, putative Get druggable targets OG5_127333 All targets in OG5_127333
Trichomonas vaginalis ABC transporter, putative Get druggable targets OG5_126596 All targets in OG5_126596
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Plasmodium falciparum steroid dehydrogenase, putative hydroxyprostaglandin dehydrogenase 15-(NAD) 266 aa 216 aa 22.2 %
Mycobacterium tuberculosis Succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD1 aldehyde dehydrogenase 1 family, member A1 501 aa 456 aa 33.3 %
Mycobacterium tuberculosis Hypothetical protein Nonstructural protein 1   230 aa 202 aa 23.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0262 0.1328
Onchocerca volvulus 0.002 0.0262 1
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0016 0.0189 0.1546
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0013 0.0127 0.0114
Onchocerca volvulus 0.0016 0.0189 0.4584
Toxoplasma gondii sugar transporter ST3 0.0016 0.0189 0.0327
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0007 0.0018 0.002
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0013 0.0127 0.0642
Leishmania major glucose transporter, lmgt3 0.0036 0.0542 0.4198
Loa Loa (eye worm) hypothetical protein 0.0016 0.0189 0.0894
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.001 0.0085 0.0659
Toxoplasma gondii lysine-tRNA ligase 0.0026 0.0361 0.0625
Echinococcus granulosus cathepsin L cysteine protease 0.001 0.0085 0.0072
Echinococcus granulosus multidrug resistance protein 1 0.0013 0.0127 0.0114
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0014 0.0141 0.0716
Echinococcus multilocularis solute carrier family 22 0.0016 0.0189 0.0176
Trichomonas vaginalis conserved hypothetical protein 0.0115 0.1977 1
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.004 0.0624 0.4836
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0013 0.0127 0.0642
Loa Loa (eye worm) hypothetical protein 0.0028 0.0404 0.1987
Leishmania major cathepsin L-like protease 0.002 0.0262 0.2034
Chlamydia trachomatis proline--tRNA ligase 0.0012 0.0117 0.2978
Entamoeba histolytica cysteine protease, putative 0.001 0.0085 0.1104
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0189 0.0956
Trypanosoma cruzi hexose transporter, putative 0.0036 0.0542 0.4198
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0262 0.1328
Brugia malayi Papain family cysteine protease containing protein 0.002 0.0262 0.1268
Echinococcus granulosus multidrug resistance protein 1 0.0009 0.0057 0.0044
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.001 0.0085 0.0659
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0026 0.0361 0.295
Brugia malayi Cathepsin L-like precursor 0.002 0.0262 0.1268
Loa Loa (eye worm) hypothetical protein 0.0034 0.0521 0.2583
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0189 0.0956
Toxoplasma gondii NAC domain-containing protein 0.0042 0.066 0.1144
Leishmania major cathepsin L-like protease 0.002 0.0262 0.2034
Leishmania major cathepsin L-like protease 0.0077 0.129 1
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0035 0.0534 0.0925
Onchocerca volvulus 0.0016 0.0189 0.4584
Plasmodium falciparum calcium-dependent protein kinase 4 0.0035 0.0534 0.0597
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.001 0.0085 0.0364
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0013 0.0127 0.0642
Mycobacterium ulcerans integral membrane transport protein 0.0016 0.0189 0.1546
Brugia malayi beta-NAC-like protein 0.0042 0.066 0.3295
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0035 0.0534 0.0521
Echinococcus multilocularis cathepsin l cysteine peptidase 0.002 0.0262 0.0249
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0262 0.1328
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.129 1
Brugia malayi Cathepsin L-like precursor 0.002 0.0262 0.1268
Loa Loa (eye worm) major facilitator superfamily transporter 0.0016 0.0189 0.0894
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.1223 1
Plasmodium falciparum hexose transporter 0.0115 0.1977 0.2253
Trypanosoma cruzi hexose transporter, putative 0.0016 0.0189 0.1465
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.004 0.0624 0.4836
Schistosoma mansoni cathepsin F (C01 family) 0.002 0.0262 0.1268
Trypanosoma cruzi hexose transporter, putative 0.0019 0.0249 0.1931
Plasmodium falciparum lysine--tRNA ligase 0.0026 0.0361 0.0399
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0026 0.0361 0.1826
Onchocerca volvulus 0.0016 0.0189 0.4584
Entamoeba histolytica P-glycoprotein-2 0.0013 0.0127 0.1752
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0073 0.1223 0.1211
Loa Loa (eye worm) ctsf protein 0.002 0.0262 0.1268
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0026 0.0361 0.2796
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0189 0.0956
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0013 0.0127 0.0642
Plasmodium falciparum cysteine proteinase falcipain 1 0.001 0.0085 0.0082
Entamoeba histolytica cysteine proteinase, putative 0.001 0.0085 0.1104
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0189 0.0956
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0073 0.1223 0.1211
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0262 0.1328
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0013 0.0127 0.0642
Echinococcus multilocularis lysyl tRNA synthetase 0.0026 0.0361 0.0348
Entamoeba histolytica cysteine proteinase, putative 0.001 0.0085 0.1104
Giardia lamblia Hexose transporter 0.0016 0.0189 0.346
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0189 0.0956
Echinococcus multilocularis cathepsin L 0.001 0.0085 0.0072
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.129 1
Plasmodium falciparum protein kinase 7 0.0325 0.5773 0.6612
Leishmania major cathepsin L-like protease 0.002 0.0262 0.2034
Brugia malayi Cathepsin L-like precursor 0.002 0.0262 0.1268
Brugia malayi multidrug resistance protein 3 0.0013 0.0127 0.0577
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0026 0.0361 0.6932
Onchocerca volvulus 0.0016 0.0189 0.4584
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0035 0.0534 0.0597
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0034 0.0521 0.2634
Schistosoma mansoni aldehyde dehydrogenase 0.0073 0.1223 0.6162
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0189 0.0956
Loa Loa (eye worm) hypothetical protein 0.0016 0.0189 0.0894
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0016 0.0189 0.1546
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0189 0.0956
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0189 0.0956
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0542 0.274
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0115 0.1977 0.1966
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0189 0.0956
Loa Loa (eye worm) ICD-1 protein 0.0042 0.066 0.3295
Plasmodium falciparum cysteine proteinase falcipain 2a 0.002 0.0262 0.0286
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0035 0.0534 0.0597
Trichomonas vaginalis ABC transporter, putative 0.0013 0.0127 0.0642
Echinococcus granulosus solute carrier family 22 0.0016 0.0189 0.0176
Leishmania major cathepsin L-like protease 0.0077 0.129 1
Loa Loa (eye worm) hypothetical protein 0.0016 0.0189 0.0894
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0013 0.0127 0.0642
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.129 1
Schistosoma mansoni transcription factor btf3 0.0042 0.066 0.3295
Entamoeba histolytica P-glycoprotein-2 0.0013 0.0127 0.1752
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0035 0.0534 0.2648
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0542 0.274
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0189 0.0956
Trypanosoma brucei glucose transporter, putative 0.0036 0.0542 0.4198
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0013 0.0127 0.0642
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.129 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.1223 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.129 1
Echinococcus granulosus neuropeptide receptor A26 0.0558 1 1
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0186 0.3258 0.3724
Loa Loa (eye worm) hypothetical protein 0.0016 0.0189 0.0894
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0262 0.1328
Trypanosoma cruzi cysteine peptidase, putative 0.0077 0.129 1
Onchocerca volvulus 0.002 0.0262 1
Onchocerca volvulus Cathepsin F homolog 0.002 0.0262 1
Schistosoma mansoni glucose transporter 0.0016 0.0189 0.0894
Onchocerca volvulus 0.0016 0.0189 0.4584
Leishmania major protein kinase, putative 0.0035 0.0534 0.4134
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0189 0.0956
Toxoplasma gondii glycyl-tRNA synthetase 0.0006 0.0014 0.0024
Echinococcus granulosus cathepsin L 0.001 0.0085 0.0072
Entamoeba histolytica P-glycoprotein-5 0.0013 0.0127 0.1752
Trypanosoma brucei glucose transporter, putative 0.0036 0.0542 0.4198
Trypanosoma cruzi transcription factor btf3, putative 0.0042 0.066 0.5118
Loa Loa (eye worm) hypothetical protein 0.0034 0.0521 0.2583
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0013 0.0127 0.0984
Plasmodium vivax basic transcription factor 3b, putative 0.0042 0.066 0.0743
Echinococcus multilocularis cathepsin L cysteine protease 0.002 0.0262 0.0249
Loa Loa (eye worm) papain family cysteine protease containing protein 0.002 0.0262 0.1268
Entamoeba histolytica protein kinase, putative 0.0035 0.0534 0.8037
Trypanosoma cruzi cysteine peptidase, putative 0.001 0.0085 0.0659
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0013 0.0127 0.0114
Entamoeba histolytica cysteine protease, putative 0.001 0.0085 0.1104
Plasmodium vivax multidrug resistance protein 1, putative 0.0013 0.0127 0.013
Echinococcus multilocularis cysteine protease 0.002 0.0262 0.0249
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0034 0.0521 0.0508
Entamoeba histolytica cysteine protease, putative 0.001 0.0085 0.1104
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0262 0.1328
Entamoeba histolytica cysteine proteinase 2 0.001 0.0085 0.1104
Leishmania major basic transcription factor 3a, putative 0.0042 0.066 0.5118
Echinococcus granulosus multidrug resistance protein 1 0.0013 0.0127 0.0114
Trichomonas vaginalis abcb9, putative 0.0013 0.0127 0.0642
Entamoeba histolytica transcription factor BTF3, putative 0.0042 0.066 1
Plasmodium vivax vivapain-2 0.002 0.0262 0.0286
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.004 0.0624 0.1081
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0013 0.0127 0.0642
Brugia malayi Cathepsin L-like precursor 0.002 0.0262 0.1268
Trypanosoma brucei glucose transporter, putative 0.0036 0.0542 0.4198
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0189 0.0956
Toxoplasma gondii facilitative glucose transporter GT1 0.0115 0.1977 0.3424
Trichomonas vaginalis CAMK family protein kinase 0.0035 0.0534 0.2699
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0115 0.1977 0.1966
Entamoeba histolytica cysteine protease, putative 0.001 0.0085 0.1104
Trypanosoma brucei glucose transporter, putative 0.0036 0.0542 0.4198
Trypanosoma brucei THT1 - hexose transporter, putative 0.0036 0.0542 0.4198
Echinococcus granulosus multidrug resistance protein 1 0.0013 0.0127 0.0114
Onchocerca volvulus 0.0016 0.0189 0.4584
Brugia malayi cathepsin L-like precursor 0.0014 0.0141 0.0651
Trypanosoma cruzi hexose transporter, putative 0.0036 0.0542 0.4198
Trichomonas vaginalis glucose transporter, putative 0.0036 0.0542 0.274
Entamoeba histolytica cysteine protease, putative 0.001 0.0085 0.1104
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0013 0.0127 0.0114
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0035 0.0534 0.0521
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0013 0.0127 0.022
Trypanosoma brucei glycyl-tRNA synthetase, putative 0.0006 0.0014 0.0106
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0262 0.1328
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0013 0.0127 0.0642
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.1223 1
Loa Loa (eye worm) hypothetical protein 0.0016 0.0189 0.0894
Plasmodium vivax unspecified product 0.0007 0.0018 0.0005
Loa Loa (eye worm) sugar transporter 0.0016 0.0189 0.0894
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.007 0.1169 0.9063
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0189 0.0956
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0035 0.0534 0.0521
Loa Loa (eye worm) cysteine protease 0.002 0.0262 0.1268
Toxoplasma gondii transporter, major facilitator family protein 0.0016 0.0189 0.0327
Schistosoma mansoni sugar transporter 0.0016 0.0189 0.0894
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0013 0.0127 0.0642
Schistosoma mansoni glucose transport protein 0.0115 0.1977 1
Brugia malayi major facilitator superfamily protein 0.0016 0.0189 0.0894
Onchocerca volvulus 0.002 0.0262 1
Onchocerca volvulus 0.0016 0.0189 0.4584
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0189 0.0956
Trichomonas vaginalis ABC transporter, putative 0.0013 0.0127 0.0642
Treponema pallidum prolyl-tRNA synthetase 0.0012 0.0117 1
Leishmania major glucose transporter/membrane transporter D2, putative 0.0036 0.0542 0.4198
Echinococcus multilocularis cathepsin L cysteine protease 0.002 0.0262 0.0249
Trypanosoma cruzi cysteine protease, putative 0.001 0.0085 0.0659
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.002 0.0262 0.1328
Onchocerca volvulus Cathepsin L homolog 0.002 0.0262 1
Echinococcus granulosus General substrate transporter 0.0099 0.1684 0.1673
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0013 0.0127 0.3264
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0073 0.1223 1
Brugia malayi Major Facilitator Superfamily protein 0.0016 0.0189 0.0894
Mycobacterium ulcerans sugar transporter 0.0016 0.0189 0.1546
Echinococcus multilocularis solute carrier family 22 0.0016 0.0189 0.0176
Chlamydia trachomatis lysine--tRNA ligase 0.0026 0.0361 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0262 0.1328
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0014 0.0141 0.0716
Brugia malayi Major Facilitator Superfamily protein 0.0016 0.0189 0.0894
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0073 0.1223 0.9479
Plasmodium falciparum proline--tRNA ligase 0.004 0.0624 0.0701
Trichomonas vaginalis sugar transporter, putative 0.0036 0.0542 0.274
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0189 0.0956
Trypanosoma cruzi cysteine peptidase, putative 0.0007 0.0018 0.0136
Loa Loa (eye worm) hypothetical protein 0.0016 0.0189 0.0894
Echinococcus granulosus solute carrier family 22 0.0016 0.0189 0.0176
Brugia malayi Cathepsin L-like cysteine proteinase 0.0014 0.0141 0.0651
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0262 0.1328
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0034 0.0521 0.2583
Toxoplasma gondii protein kinase, putative 0.0325 0.5773 1
Plasmodium falciparum cysteine proteinase falcipain 2b 0.002 0.0262 0.0286
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.001 0.0085 0.043
Echinococcus granulosus synaptic vesicle 2 protein 0.0016 0.0189 0.0176
Trichomonas vaginalis taga, putative 0.0013 0.0127 0.0642
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0034 0.0521 0.2583
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0115 0.1977 0.1966
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0189 0.0956
Entamoeba histolytica P-glycoprotein 5, putative 0.0013 0.0127 0.1752
Loa Loa (eye worm) multidrug resistance protein 3 0.0013 0.0127 0.0577
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0262 0.1328
Loa Loa (eye worm) hypothetical protein 0.0016 0.0189 0.0894
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.004 0.0624 0.4836
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.129 1
Loa Loa (eye worm) hypothetical protein 0.0016 0.0189 0.0894
Entamoeba histolytica cysteine protease, putative 0.001 0.0085 0.1104
Onchocerca volvulus Cathepsin L homolog 0.002 0.0262 1
Onchocerca volvulus 0.0016 0.0189 0.4584
Loa Loa (eye worm) hypothetical protein 0.0007 0.0018 0.002
Brugia malayi Major Facilitator Superfamily protein 0.0016 0.0189 0.0894
Trypanosoma brucei glucose transporter, putative 0.0036 0.0542 0.4198
Loa Loa (eye worm) hypothetical protein 0.0016 0.0189 0.0894
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0035 0.0534 0.2648
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0016 0.0189 0.0894
Schistosoma mansoni serine/threonine protein kinase 0.0035 0.0534 0.2648
Onchocerca volvulus 0.0016 0.0189 0.4584
Trypanosoma cruzi cysteine proteinase, putative 0.001 0.0085 0.0659
Entamoeba histolytica cysteine protease, putative 0.001 0.0085 0.1104
Trypanosoma cruzi cysteine peptidase, putative 0.0077 0.129 1
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0189 0.0956
Echinococcus multilocularis General substrate transporter 0.0099 0.1684 0.1673
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.066 0.3342
Toxoplasma gondii threonyl-tRNA synthetase family protein 0.0006 0.0014 0.0024
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0022 0.0291 0.2378
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0115 0.1977 0.1966
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0034 0.0521 0.7838
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0189 0.0956
Entamoeba histolytica cysteine protease, putative 0.001 0.0085 0.1104
Echinococcus multilocularis ATP binding cassette sub family B 0.0013 0.0124 0.0111
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0035 0.0534 0.0521
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0034 0.0521 1
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0013 0.0127 0.0642
Echinococcus granulosus cathepsin L cysteine proteinase 0.002 0.0262 0.0249
Brugia malayi Sugar transporter family protein 0.0016 0.0189 0.0894
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0115 0.1977 0.1966
Loa Loa (eye worm) hypothetical protein 0.0035 0.0534 0.2648
Brugia malayi hypothetical protein 0.0016 0.0189 0.0894
Entamoeba histolytica cysteine protease, putative 0.001 0.0085 0.1104
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0189 0.0956
Brugia malayi Cathepsin L-like precursor 0.0007 0.0018 0.002
Brugia malayi Papain family cysteine protease containing protein 0.001 0.0085 0.0364
Leishmania major threonyl-tRNA synthetase, putative 0.0006 0.0014 0.0106
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0026 0.0361 0.2796
Trichomonas vaginalis glucose transporter, putative 0.0016 0.0189 0.0956
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0262 0.1328
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0013 0.0127 0.0114
Loa Loa (eye worm) fibroinase 0.002 0.0262 0.1268
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.129 1
Entamoeba histolytica cysteine proteinase, putative 0.001 0.0085 0.1104
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0013 0.0127 0.0642
Echinococcus multilocularis neuropeptide s receptor 0.0558 1 1
Trypanosoma cruzi hexose transporter, putative 0.0036 0.0542 0.4198
Plasmodium falciparum calcium-dependent protein kinase 2 0.0035 0.0534 0.0597
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0013 0.0127 0.0114
Schistosoma mansoni protein kinase 0.0035 0.0534 0.2648
Plasmodium falciparum calcium-dependent protein kinase 5 0.0035 0.0534 0.0597
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0013 0.0124 0.0111
Loa Loa (eye worm) major facilitator superfamily transporter 0.0016 0.0189 0.0894
Schistosoma mansoni cathepsin F (C01 family) 0.0014 0.0141 0.0651
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0189 0.0956
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0013 0.0127 0.0577
Trypanosoma brucei glucose transporter 2A 0.0036 0.0542 0.4198
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.001 0.0085 0.0659
Trypanosoma brucei THT1 - hexose transporter, putative 0.0036 0.0542 0.4198
Brugia malayi Cam kinase protein 1 0.0035 0.0534 0.2648
Mycobacterium ulcerans threonyl-tRNA synthetase 0.0006 0.0014 0.0111
Trichomonas vaginalis sugar transporter, putative 0.0036 0.0542 0.274
Entamoeba histolytica cysteine protease, putative 0.001 0.0085 0.1104
Plasmodium falciparum cysteine proteinase falcipain 3 0.002 0.0262 0.0286
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0034 0.0521 0.0508
Giardia lamblia Prolyl-tRNA synthetase 0.0034 0.0521 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0262 0.1328
Entamoeba histolytica P-glycoprotein-1 0.0013 0.0127 0.1752
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.002 0.0262 0.1268
Echinococcus multilocularis multidrug resistance protein 1 0.0013 0.0127 0.0114
Leishmania major glucose transporter, lmgt2 0.0036 0.0542 0.4198
Onchocerca volvulus 0.0016 0.0189 0.4584
Plasmodium falciparum multidrug resistance protein 1 0.0013 0.0127 0.013
Echinococcus multilocularis multidrug resistance protein 1 0.0009 0.0057 0.0044
Loa Loa (eye worm) hypothetical protein 0.0013 0.0124 0.0565
Plasmodium vivax vivapain-3 0.001 0.0085 0.0082
Echinococcus granulosus cysteine protease 0.001 0.0085 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0189 0.0956
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.129 1
Loa Loa (eye worm) hypothetical protein 0.0016 0.0189 0.0894
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0013 0.0127 0.0114
Onchocerca volvulus 0.002 0.0262 1
Trichomonas vaginalis sugar transport protein, putative 0.0016 0.0189 0.0956
Entamoeba histolytica cysteine protease, putative 0.001 0.0085 0.1104
Onchocerca volvulus Putative transporter 0.0016 0.0189 0.4584
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0189 0.0956
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0189 0.0956
Entamoeba histolytica cysteine proteinase, putative 0.002 0.0262 0.3846
Trypanosoma cruzi transcription factor btf3, putative 0.0042 0.066 0.5118
Entamoeba histolytica cysteine proteinase, putative 0.0014 0.0141 0.1977
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0013 0.0127 0.0642
Onchocerca volvulus 0.0016 0.0189 0.4584
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.001 0.0085 0.043
Onchocerca volvulus 0.002 0.0262 1
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0035 0.0534 0.0521
Trichomonas vaginalis threonyl-tRNA synthetase, putative 0.0006 0.0014 0.0069
Toxoplasma gondii aldehyde dehydrogenase 0.0073 0.1223 0.2119
Plasmodium falciparum calcium-dependent protein kinase 1 0.0035 0.0534 0.0597
Echinococcus multilocularis solute carrier family 22 0.0016 0.0189 0.0176
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0262 0.1328
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.129 1
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0034 0.0521 0.2583
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0035 0.0534 0.0521
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0013 0.0127 0.0642
Leishmania major cathepsin L-like protease 0.002 0.0262 0.2034
Toxoplasma gondii cathepsin CPL 0.002 0.0262 0.0455
Entamoeba histolytica cysteine proteinase, putative 0.001 0.0085 0.1104
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0035 0.0534 0.4134
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.002 0.0262 0.1328
Echinococcus multilocularis synaptic vesicle 2 protein 0.0016 0.0189 0.0176
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0262 0.1328
Echinococcus multilocularis solute carrier family 22 0.0016 0.0189 0.0176
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0013 0.0127 0.0114
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0013 0.0127 0.0642
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.001 0.0085 0.0364
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0262 0.1328
Trypanosoma cruzi hexose transporter 0.0036 0.0542 0.4198
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0006 0.0014 0.0106
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0189 0.0956
Schistosoma mansoni lysyl-tRNA synthetase 0.0026 0.0361 0.1769
Loa Loa (eye worm) hypothetical protein 0.0013 0.0127 0.0577
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0016 0.0189 0.0201
Brugia malayi Sugar transporter family protein 0.0016 0.0189 0.0894
Brugia malayi hypothetical protein 0.0016 0.0189 0.0894
Plasmodium falciparum calcium-dependent protein kinase 3 0.0035 0.0534 0.0597
Trypanosoma brucei glucose transporter, putative 0.0036 0.0542 0.4198
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0006 0.0014 0.0106
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0189 0.0956
Brugia malayi Sugar transporter family protein 0.0115 0.1977 1
Loa Loa (eye worm) sugar transporter 0.0115 0.1977 1
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0013 0.0127 0.0114
Trypanosoma brucei glucose transporter, putative 0.0036 0.0542 0.4198
Trypanosoma cruzi cruzipain precursor, putative 0.0007 0.0018 0.0136
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0189 0.0956
Loa Loa (eye worm) hypothetical protein 0.0014 0.0141 0.0651
Schistosoma mansoni sugar transporter 0.0016 0.0189 0.0894
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0022 0.0291 0.5587
Brugia malayi Papain family cysteine protease containing protein 0.001 0.0085 0.0364
Plasmodium vivax sugar transporter, putative 0.0016 0.0189 0.0201
Brugia malayi Cathepsin L-like precursor 0.002 0.0262 0.1268
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0189 0.0956
Echinococcus granulosus multidrug resistance protein 1 0.0009 0.0057 0.0044
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.004 0.0624 0.4836
Trypanosoma brucei THT1 - hexose transporter, putative 0.0036 0.0542 0.4198
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0009 0.0057 0.029
Leishmania major glucose transporter, lmgt1 0.0036 0.0542 0.4198
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0016 0.0189 0.1546
Schistosoma mansoni multidrug resistance protein 0.0013 0.0127 0.0577
Leishmania major p-glycoprotein 0.0013 0.0127 0.0984
Onchocerca volvulus 0.002 0.0262 1
Trichomonas vaginalis ABC transporter, putative 0.0013 0.0127 0.0642
Loa Loa (eye worm) hypothetical protein 0.0016 0.0189 0.0894
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0186 0.3258 0.5643
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0115 0.1977 0.1966
Echinococcus multilocularis transcription factor btf3 0.0042 0.066 0.0648
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0016 0.0189 0.1546
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.129 1
Giardia lamblia Sugar-proton symporter 0.0016 0.0189 0.346
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0189 0.0956
Onchocerca volvulus 0.002 0.0262 1
Trypanosoma cruzi cruzipain precursor, putative 0.0077 0.129 1
Schistosoma mansoni sugar transporter 0.0016 0.0189 0.0894
Trichomonas vaginalis abcb9, putative 0.0013 0.0127 0.0642
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0013 0.0127 0.022
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0022 0.0304 0.1536
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0189 0.0956
Plasmodium vivax vivapain-1 0.001 0.0085 0.0082
Schistosoma mansoni glucose transport protein 0.0115 0.1977 1
Toxoplasma gondii sugar transporter ST2 0.0016 0.0189 0.0327
Leishmania major cathepsin L-like protease 0.002 0.0262 0.2034
Echinococcus granulosus cathepsin l1 0.0014 0.0141 0.0128
Brugia malayi Cathepsin L-like precursor 0.0014 0.0141 0.0651
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0262 0.1328
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0189 0.0956
Loa Loa (eye worm) hypothetical protein 0.0007 0.0018 0.002
Trichomonas vaginalis sugar transporter, putative 0.0036 0.0542 0.274
Trypanosoma brucei threonyl-tRNA synthetase, putative 0.0006 0.0014 0.0106
Plasmodium falciparum basic transcription factor 3b, putative 0.0042 0.066 0.0743
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0189 0.0956
Loa Loa (eye worm) hypothetical protein 0.0014 0.0141 0.0651
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0035 0.0534 0.0521
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0115 0.1977 0.1966
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0035 0.0534 0.0925
Plasmodium vivax vivapain-2 0.002 0.0262 0.0286
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0013 0.0127 0.1038
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0034 0.0521 0.2583
Onchocerca volvulus 0.0016 0.0189 0.4584
Loa Loa (eye worm) hypothetical protein 0.0016 0.0189 0.0894
Mycobacterium ulcerans glycyl-tRNA synthetase 0.0006 0.0014 0.0111
Schistosoma mansoni hypothetical protein 0.0115 0.1977 1
Trypanosoma brucei transcription factor BTF3, putative 0.0042 0.066 0.5118
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0189 0.0956
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0022 0.0291 0.2378
Leishmania major lysyl-tRNA synthetase, putative 0.0026 0.0361 0.2796
Echinococcus granulosus solute carrier family 22 0.0016 0.0189 0.0176
Echinococcus granulosus cathepsin l cysteine peptidase 0.002 0.0262 0.0249
Schistosoma mansoni multidrug resistance protein 0.0013 0.0127 0.0577
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0013 0.0127 0.0114
Brugia malayi ABC transporter family protein 0.0013 0.0127 0.0577
Trypanosoma brucei glucose transporter 1E 0.0036 0.0542 0.4198
Leishmania major cysteine peptidase A (CPA) 0.002 0.0262 0.2034
Trichomonas vaginalis glucose transporter, putative 0.0036 0.0542 0.274
Onchocerca volvulus 0.0016 0.0189 0.4584
Plasmodium vivax lysine--tRNA ligase, putative 0.0026 0.0361 0.0399
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.066 0.3342
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0026 0.0361 0.295
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0013 0.0127 0.0642
Echinococcus multilocularis cysteine protease 0.002 0.0262 0.0249
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.129 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.0361 0.1769
Loa Loa (eye worm) hypothetical protein 0.002 0.0262 0.1268
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0262 0.1328
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0035 0.0534 0.0521
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0189 0.0956
Entamoeba histolytica cysteine proteinase, putative 0.002 0.0262 0.3846
Onchocerca volvulus 0.0016 0.0189 0.4584
Onchocerca volvulus 0.0014 0.0141 0.1072
Schistosoma mansoni protein kinase 0.0035 0.0534 0.2648
Trichomonas vaginalis abcb9, putative 0.0013 0.0127 0.0642
Trypanosoma cruzi glucose transporter, putative 0.0016 0.0189 0.1465
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0262 0.1328
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0013 0.0127 0.0642
Onchocerca volvulus 0.0016 0.0189 0.4584
Schistosoma mansoni cathepsin F (C01 family) 0.002 0.0262 0.1268
Schistosoma mansoni sugar transporter 0.0016 0.0189 0.0894
Entamoeba histolytica P-glyco protein 6, putative 0.0013 0.0127 0.1752
Schistosoma mansoni protein kinase 0.0035 0.0534 0.2648
Plasmodium vivax hexose transporter 0.0115 0.1977 0.2253
Echinococcus multilocularis cathepsin l cysteine peptidase 0.002 0.0262 0.0249
Loa Loa (eye worm) hypothetical protein 0.0013 0.0127 0.0577
Loa Loa (eye worm) hypothetical protein 0.0016 0.0189 0.0894
Echinococcus multilocularis neuropeptide receptor A26 0.0558 1 1
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.001 0.0085 0.0364
Echinococcus granulosus lysyl tRNA synthetase 0.0026 0.0361 0.0348
Loa Loa (eye worm) hypothetical protein 0.0014 0.0141 0.0651
Schistosoma mansoni glucose transport protein 0.0115 0.1977 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0262 0.1328
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.004 0.0624 0.4836
Toxoplasma gondii sugar transporter ST1 0.0016 0.0189 0.0327
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0189 0.0956
Onchocerca volvulus 0.0016 0.0189 0.4584
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0115 0.1977 0.1966
Brugia malayi lysyl-tRNA synthetase 0.0026 0.0361 0.1769
Entamoeba histolytica cysteine protease, putative 0.001 0.0085 0.1104
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0262 0.1328
Brugia malayi cathepsin F-like cysteine proteinase 0.0007 0.0018 0.002
Echinococcus granulosus solute carrier family 22 0.0016 0.0189 0.0176
Brugia malayi Cathepsin L-like precursor 0.002 0.0262 0.1268
Trypanosoma cruzi cysteine peptidase, putative 0.002 0.0262 0.2034
Echinococcus multilocularis multidrug resistance protein 1 0.0013 0.0127 0.0114
Echinococcus granulosus calcium dependent protein kinase 0.0033 0.0494 0.0481
Trypanosoma brucei sugar transporter, putative 0.0016 0.0189 0.1465
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0035 0.0534 0.2648
Trichomonas vaginalis ABC transporter, putative 0.0013 0.0127 0.0642
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0013 0.0127 0.0642
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0189 0.0956
Mycobacterium leprae Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase) (ThrRS) (Threonine-tRNA ligase) 0.0006 0.0014 0.0262
Leishmania major hypothetical protein, conserved 0.0016 0.0189 0.1465
Entamoeba histolytica hypothetical protein 0.0042 0.066 1
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0016 0.0189 0.1465
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0013 0.0127 0.0642
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0012 0.0117 0.0957
Trichomonas vaginalis myo-inositol transporter, putative 0.0016 0.0189 0.0956
Schistosoma mansoni lysyl-tRNA synthetase 0.0026 0.0361 0.1769
Entamoeba histolytica cysteine protease, putative 0.001 0.0085 0.1104
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.066 0.3342
Brugia malayi hypothetical protein 0.0016 0.0189 0.0894
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0262 0.1328
Mycobacterium tuberculosis Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase)(ThrRS) (threonine-tRNA ligase) 0.0006 0.0014 0.0111
Plasmodium vivax calcium-dependent protein kinase, putative 0.0035 0.0534 0.0597
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0262 0.1328
Loa Loa (eye worm) hypothetical protein 0.0007 0.0018 0.002
Schistosoma mansoni aldehyde dehydrogenase 0.0073 0.1223 0.6162
Plasmodium falciparum protein kinase 6 0.0488 0.8724 1
Echinococcus multilocularis calcium dependent protein kinase 0.0033 0.0494 0.0481
Schistosoma mansoni multidrug resistance protein 0.0013 0.0127 0.0577
Giardia lamblia Lysyl-tRNA synthetase 0.0026 0.0361 0.6849
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0189 0.0956
Leishmania major cathepsin L-like protease 0.0077 0.129 1
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0189 0.0956
Echinococcus granulosus Sugar transporter ERD6 protein 0.0016 0.0189 0.0176
Plasmodium vivax unspecified product 0.001 0.0085 0.0082
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0035 0.0534 0.0925
Schistosoma mansoni smdr2 0.0013 0.0127 0.0577
Trypanosoma cruzi cysteine peptidase, putative 0.0077 0.129 1
Trypanosoma cruzi major cysteine proteinase, putative 0.0061 0.0992 0.7688
Echinococcus granulosus cathepsin l1 0.002 0.0262 0.0249
Trypanosoma brucei glucose transporter, putative 0.0036 0.0542 0.4198
Plasmodium vivax CDK-related protein kinase 6, putative 0.0488 0.8724 1
Loa Loa (eye worm) hypothetical protein 0.0016 0.0189 0.0894
Plasmodium falciparum mitogen-activated protein kinase 2 0.0186 0.3258 0.3724
Entamoeba histolytica hypothetical protein 0.0026 0.0361 0.5368
Brugia malayi Cathepsin L-like precursor 0.0014 0.0141 0.0651
Entamoeba histolytica cysteine protease, putative 0.002 0.0262 0.3846
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0016 0.0189 0.0176
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0035 0.0534 0.0597
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0014 0.0153 0.0709
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0007 0.0018 0.002
Loa Loa (eye worm) hypothetical protein 0.0016 0.0189 0.0894
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0016 0.0189 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0262 0.1328
Entamoeba histolytica cysteine proteinase 1, putative 0.001 0.0085 0.1104
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0189 0.0956
Trypanosoma cruzi sugar transporter, putative 0.0016 0.0189 0.1465
Schistosoma mansoni cathepsin s 0.0007 0.0018 0.002
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0189 0.0956
Entamoeba histolytica P-glycoprotein-2, putative 0.0013 0.0127 0.1752
Echinococcus granulosus transcription factor btf3 0.0042 0.066 0.0648
Brugia malayi major facilitator superfamily protein 0.0016 0.0189 0.0894
Trypanosoma cruzi cysteine proteinase, putative 0.001 0.0085 0.0659
Entamoeba histolytica protein kinase, putative 0.0035 0.0534 0.8037
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0013 0.0127 0.0642
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0013 0.0127 0.0642
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0013 0.0127 0.0642
Plasmodium vivax proline--tRNA ligase, putative 0.004 0.0624 0.0701
Leishmania major myo-inositol/proton symporter (MIT) 0.0016 0.0189 0.1465
Trichomonas vaginalis sugar transporter, putative 0.0016 0.0189 0.0956

Activities

Activity type Activity value Assay description Source Reference
EC50 (functional) = 6.187 um PUBCHEM_BIOASSAY: Luminescence Microorganism-Based Dose Confirmation HTS to Identify Inhibitors of Streptokinase Promotor Activity. (Class of assay: confirmatory) [Related pubchem assays: 1677 (Project Summary), 1662 (Primary HTS)] ChEMBL. No reference
EC50 (functional) 6.22 uM PubChem BioAssay. Dose Response for ABC transporter inhibitors: specifically ABCG2 screen, ABCB1 counter-screen. Follow-up assay on set 2. (Class of assay: confirmatory) ChEMBL. No reference
EC50 (functional) = 8.618 um PUBCHEM_BIOASSAY: Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression. (Class of assay: confirmatory) [Related pubchem assays: 1677 (Project Summary), 1902 (Retest at Dose), 1900 (Counter Screen), 1662 (Primary HTS)] ChEMBL. No reference
EC50 (functional) 11.15 uM PubChem BioAssay. Dose Response for ABC transporter inhibitors: specifically ABCB1 screen, ABCG2 counter-screen. Follow-up assay for Set 2. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 4.6535 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) = 6.3096 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] ChEMBL. No reference
Potency (functional) = 10 um PUBCHEM_BIOASSAY: qHTS Assay for Antagonists of the Neuropeptide S Receptor: cAMP Signal Transduction. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 10.4179 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) = 12.5893 um PUBCHEM_BIOASSAY: qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (without detergent). (Class of assay: confirmatory) [Related pubchem assays: 2158 (Confirmation qHTS Assay for Inhibitors of Cruzain), 2249 (Probe Development Summary of Promiscuous Inhibitors (Artifacts) of Cruzain), 2161 (qHTS Assay for Inhibitors of Papain: Counterscreen for Cruzain Assay), 1478 (qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (with detergent))] ChEMBL. No reference
Potency (functional) = 17.7828 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase). (Class of assay: confirmatory) [Related pubchem assays: 2429 (Confirmation qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase)), 2407 (Probe Development Summary for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase)), 2427 (Thermal Shift Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase))] ChEMBL. No reference
Potency (functional) = 19.9526 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Influenza NS1 Protein Function. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 35.4813 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Human alpha-Glucosidase as a Potential Chaperone Treatment of Pompe Disease. (Class of assay: confirmatory) [Related pubchem assays: 997 ] ChEMBL. No reference
Potency (functional) = 35.4813 um PUBCHEM_BIOASSAY: qHTS Assay for Activators of Human alpha-Glucosidase as a Potential Chaperone Treatment of Pompe Disease. (Class of assay: confirmatory) [Related pubchem assays: 1467, 2100, 2112, 1473, 1466 ] ChEMBL. No reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of HADH2 (Hydroxyacyl-Coenzyme A Dehydrogenase, Type II). (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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