Detailed information for compound 1487121

Basic information

Technical information
  • TDR Targets ID: 1487121
  • Name: N-(3-carbamoylthiophen-2-yl)-2,5-dimethylfura n-3-carboxamide
  • MW: 264.3 | Formula: C12H12N2O3S
  • H donors: 2 H acceptors: 2 LogP: 2.06 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1oc(c(c1)C(=O)Nc1sccc1C(=O)N)C
  • InChi: 1S/C12H12N2O3S/c1-6-5-9(7(2)17-6)11(16)14-12-8(10(13)15)3-4-18-12/h3-5H,1-2H3,(H2,13,15)(H,14,16)
  • InChiKey: FUURRTWWSPUJTH-UHFFFAOYSA-N  

Network

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Synonyms

  • N-(3-carbamoyl-2-thienyl)-2,5-dimethyl-furan-3-carboxamide
  • N-(3-carbamoyl-2-thienyl)-2,5-dimethyl-3-furancarboxamide
  • N-(3-carbamoyl-2-thienyl)-2,5-dimethyl-3-furamide
  • N-(3-aminocarbonylthiophen-2-yl)-2,5-dimethyl-furan-3-carboxamide
  • T5361608

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens ubiquitin specific peptidase 1 Starlite/ChEMBL No references
Homo sapiens ATPase family, AAA domain containing 5 Starlite/ChEMBL No references
Homo sapiens polymerase (DNA directed) iota Starlite/ChEMBL No references
Homo sapiens synuclein, alpha (non A4 component of amyloid precursor) Starlite/ChEMBL No references
Homo sapiens apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D Starlite/ChEMBL No references
Homo sapiens glucagon-like peptide 1 receptor Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core Get druggable targets OG5_139225 All targets in OG5_139225

By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Loa Loa (eye worm) pigment dispersing factor receptor c glucagon-like peptide 1 receptor 463 aa 388 aa 25.8 %

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Trypanosoma cruzi cdc2-related kinase 3 0.0092 0.0508 0.2604
Brugia malayi Protein kinase domain containing protein 0.0027 0.0027 0.0044
Entamoeba histolytica protein kinase, putative 0.0027 0.0027 0.0137
Brugia malayi Protein kinase domain containing protein 0.0027 0.0027 0.0044
Schistosoma mansoni tyrosine kinase 0.0027 0.0027 0.0027
Echinococcus multilocularis cyclins 0.0035 0.0087 0.0087
Brugia malayi p70 ribosomal S6 kinase beta 0.0069 0.0338 0.0558
Loa Loa (eye worm) TK/FAK protein kinase 0.0528 0.3728 0.5359
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0035 0.0084 0.0084
Loa Loa (eye worm) phosphatidylinositol glycan anchor biosynthesis protein 0.0045 0.0162 0.0232
Loa Loa (eye worm) TK/FER protein kinase 0.0038 0.011 0.0157
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0035 0.0084 0.012
Echinococcus granulosus activin receptor type 0.0035 0.0086 0.0086
Entamoeba histolytica protein kinase domain containing protein 0.0033 0.0073 0.0373
Echinococcus multilocularis lachesin 0.0035 0.0084 0.0084
Echinococcus multilocularis tyrosine protein kinase csk 0.0027 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0035 0.0084 0.012
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Trichomonas vaginalis CMGC family protein kinase 0.014 0.0858 0.4401
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.004 0.0126 0.0126
Echinococcus granulosus raf serine:threonine protein kinase 0.0027 0.0027 0.0027
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0027 0.0027 0.0137
Echinococcus granulosus natriuretic peptide receptor 1 0.0027 0.0027 0.0027
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Trichomonas vaginalis CAMK family protein kinase 0.0287 0.1949 1
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0027 0.0027 0.0027
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0026 0.0023 0.0022
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0027 0.0027 0.0044
Echinococcus multilocularis tyrosine protein kinase Srms 0.0096 0.0534 0.0534
Loa Loa (eye worm) hypothetical protein 0.0182 0.1175 0.1689
Echinococcus granulosus tyrosine protein kinase Srms 0.0038 0.011 0.0109
Giardia lamblia Kinase, PLK 0.0287 0.1949 1
Echinococcus granulosus cyclin B3 1 0.0035 0.0087 0.0086
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0027 0.0027 0.0027
Echinococcus granulosus serine threonine protein kinase nrc 0.0048 0.0186 0.0185
Echinococcus granulosus activated cdc42 kinase 1 0.0027 0.0027 0.0027
Schistosoma mansoni hemicentin 0.0026 0.0023 0.0023
Schistosoma mansoni serine/threonine protein kinase 0.0029 0.004 0.004
Brugia malayi Immunoglobulin I-set domain containing protein 0.0035 0.0084 0.0138
Trypanosoma cruzi cdc2-related kinase 1 0.0092 0.0508 0.2604
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Loa Loa (eye worm) TK/FER protein kinase 0.0027 0.0027 0.0038
Echinococcus granulosus tyrosine protein kinase csk 0.0027 0.0027 0.0027
Giardia lamblia G2/mitotic-specific cyclin B 0.0035 0.0087 0.0441
Mycobacterium ulcerans N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase MshB 0.0045 0.0162 0.0163
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0282 0.0284
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0027 0.0027 0.0027
Trypanosoma cruzi protein kinase, putative 0.0027 0.0027 0.0137
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0027 0.0027 0.0137
Entamoeba histolytica tyrosine kinase, putative 0.0027 0.0027 0.0137
Brugia malayi GCC2 and GCC3 family protein 0.0026 0.0018 0.0028
Echinococcus granulosus cyclins 0.0035 0.0087 0.0086
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0027 0.0027 0.0027
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0046 0.0166 0.0166
Echinococcus granulosus peroxidasin 0.0035 0.0084 0.0084
Schistosoma mansoni vesicular amine transporter 0.0067 0.0324 0.0324
Brugia malayi hypothetical protein 0.0027 0.0027 0.0044
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0042 0.0139 0.0139
Schistosoma mansoni serine/threonine protein kinase 0.0029 0.004 0.004
Entamoeba histolytica protein kinase domain containing protein 0.0027 0.0027 0.0137
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0029 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0102 0.058 0.0833
Schistosoma mansoni serine/threonine protein kinase 0.0029 0.004 0.004
Echinococcus multilocularis cyclin B3 1 0.0035 0.0087 0.0087
Brugia malayi Immunoglobulin I-set domain containing protein 0.0026 0.0023 0.0037
Entamoeba histolytica protein kinase, putative 0.0027 0.0027 0.0137
Loa Loa (eye worm) hypothetical protein 0.0027 0.0027 0.0038
Brugia malayi Protein kinase domain containing protein 0.0027 0.0027 0.0044
Trypanosoma brucei protein kinase, putative 0.0035 0.0086 0.044
Trypanosoma brucei cdc2-related kinase 3 0.0092 0.0508 0.2604
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0228 0.1514 0.7767
Loa Loa (eye worm) TK/EGFR protein kinase 0.0841 0.6038 0.868
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0228 0.1514 0.1514
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0096 0.0534 0.0534
Loa Loa (eye worm) TK/FER protein kinase 0.0038 0.011 0.0157
Schistosoma mansoni protein kinase 0.0027 0.0027 0.0027
Entamoeba histolytica tyrosine kinase, putative 0.0027 0.0027 0.0137
Loa Loa (eye worm) RGC/RGC protein kinase 0.0027 0.0027 0.0038
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0107 0.0615 0.0614
Echinococcus granulosus roundabout 2 0.0113 0.0662 0.0661
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0211 0.1384 0.1989
Loa Loa (eye worm) hypothetical protein 0.0035 0.0084 0.012
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0027 0.0027 0.0027
Echinococcus granulosus lachesin 0.0035 0.0084 0.0084
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0107 0.0615 0.0615
Echinococcus granulosus tyrosine protein kinase Src64B 0.0107 0.0615 0.0614
Echinococcus multilocularis protein kinase c epsilon type 0.0029 0.004 0.004
Schistosoma mansoni serine/threonine-protein kinase 0.0052 0.0215 0.0215
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0563 0.2885
Trichomonas vaginalis AGC family protein kinase 0.0073 0.0367 0.1882
Trypanosoma brucei rac serine-threonine kinase, putative 0.0073 0.0367 0.1882
Echinococcus multilocularis casein kinase ii subunit alpha 0.014 0.0858 0.0858
Echinococcus multilocularis neuroglian 0.0046 0.0166 0.0166
Brugia malayi Protein kinase domain containing protein 0.0027 0.0027 0.0044
Echinococcus granulosus roundabout 2 0.0046 0.0166 0.0166
Brugia malayi Prion-like- 0.0035 0.0084 0.0138
Echinococcus multilocularis serine:threonine protein kinase N2 0.0029 0.004 0.004
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0029 0.004 0.0056
Mycobacterium leprae Mycothiol conjugate amidase Mca (Mycothiol S-conjugate amidase) 0.1369 0.9933 1
Loa Loa (eye worm) TK protein kinase 0.0027 0.0027 0.0038
Loa Loa (eye worm) TK/FER protein kinase 0.0027 0.0027 0.0038
Onchocerca volvulus 0.0026 0.0023 0.0012
Trichomonas vaginalis cyclins, putative 0.0035 0.0087 0.0441
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0045 0.0162 0.0829
Schistosoma mansoni tyrosine kinase 0.0027 0.0027 0.0027
Loa Loa (eye worm) TK/EPH protein kinase 0.0164 0.1038 0.1491
Trichomonas vaginalis CAMK family protein kinase 0.0287 0.1949 1
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0048 0.0186 0.095
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Giardia lamblia Glucosamine-6-phosphate isomerase, putative 0.0045 0.0162 0.0829
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Entamoeba histolytica hypothetical protein 0.0027 0.0027 0.0137
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0027 0.0137
Echinococcus granulosus epidermal growth factor receptor 0.0841 0.6038 0.6038
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0027 0.0027 0.0038
Loa Loa (eye worm) hypothetical protein 0.0102 0.058 0.0833
Brugia malayi Immunoglobulin I-set domain containing protein 0.0725 0.5179 0.8577
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Echinococcus granulosus expressed protein 0.0378 0.2619 0.2618
Schistosoma mansoni tyrosine kinase 0.0543 0.3834 0.3834
Schistosoma mansoni septate junction protein 0.0035 0.0084 0.0084
Entamoeba histolytica hypothetical protein 0.0027 0.0027 0.0137
Schistosoma mansoni nephrin 0.0094 0.0519 0.0519
Echinococcus granulosus integrin linked protein kinase 0.0027 0.0027 0.0027
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0107 0.0615 0.0615
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0107 0.0615 0.0615
Brugia malayi Immunoglobulin I-set domain containing protein 0.0026 0.0023 0.0037
Onchocerca volvulus 0.0038 0.011 0.02
Brugia malayi Protein kinase domain containing protein 0.0027 0.0027 0.0044
Echinococcus granulosus cyclin B 0.0035 0.0087 0.0086
Echinococcus multilocularis serine:threonine protein kinase N2 0.0029 0.004 0.004
Onchocerca volvulus 0.0027 0.0027 0.0021
Brugia malayi hypothetical protein 0.0038 0.011 0.0181
Loa Loa (eye worm) TK protein kinase 0.0027 0.0027 0.0038
Brugia malayi Pre-SET motif family protein 0.003 0.0052 0.0085
Entamoeba histolytica receptor protein kinase, putative 0.0027 0.0027 0.0137
Loa Loa (eye worm) hypothetical protein 0.0067 0.0324 0.0465
Trichomonas vaginalis CMGC family protein kinase 0.0092 0.0508 0.2604
Brugia malayi serine/threonine protein kinase 6 0.0228 0.1514 0.2507
Loa Loa (eye worm) TK/FER protein kinase 0.0038 0.011 0.0157
Plasmodium falciparum protein kinase, putative 0.0027 0.0027 0.0065
Schistosoma mansoni tyrosine kinase 0.0027 0.0027 0.0027
Brugia malayi Receptor family ligand binding region containing protein 0.0027 0.0027 0.0044
Schistosoma mansoni septate junction protein 0.0035 0.0084 0.0084
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0052 0.0052
Onchocerca volvulus Serine\/threonine kinase homolog 0.0287 0.1949 0.4168
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0027 0.0027 0.0065
Entamoeba histolytica ankyrin repeat protein 0.0027 0.0027 0.0137
Brugia malayi Protein kinase domain containing protein 0.0027 0.0027 0.0044
Entamoeba histolytica tyrosine kinase, putative 0.0027 0.0027 0.0137
Schistosoma mansoni tyrosine kinase 0.0107 0.0615 0.0615
Loa Loa (eye worm) TK protein kinase 0.0027 0.0027 0.0038
Echinococcus multilocularis plexin a4 0.004 0.0126 0.0126
Echinococcus multilocularis N acetylglucosaminyl phosphatidylinositol 0.0045 0.0162 0.0162
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0034 0.0082 0.0117
Toxoplasma gondii protein kinase domain-containing protein 0.0027 0.0027 0.0065
Trichomonas vaginalis protein tyrosine kinase, putative 0.0027 0.0027 0.0137
Entamoeba histolytica serine/threonine kinase, putative 0.0027 0.0027 0.0137
Schistosoma mansoni serine/threonine protein kinase 0.0029 0.004 0.004
Echinococcus multilocularis integrin linked protein kinase 0.0027 0.0027 0.0027
Entamoeba histolytica serine/threonine protein kinase, putative 0.0287 0.1949 1
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Brugia malayi Immunoglobulin I-set domain containing protein 0.0046 0.0166 0.0274
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Echinococcus granulosus tyrosine protein kinase 0.0027 0.0027 0.0027
Schistosoma mansoni tyrosine kinase 0.0049 0.0191 0.0191
Schistosoma mansoni tyrosine kinase 0.0027 0.0027 0.0027
Echinococcus multilocularis tyrosine protein kinase shark 0.0038 0.011 0.011
Schistosoma mansoni protein kinase 0.0035 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0027 0.0027 0.0038
Entamoeba histolytica protein kinase domain containing protein 0.0027 0.0027 0.0137
Entamoeba histolytica protein kinase domain containing protein 0.0027 0.0027 0.0137
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0027 0.0027 0.0027
Leishmania major protein kinase, putative 0.0228 0.1514 0.7767
Entamoeba histolytica cell division protein kinase 2, putative 0.0092 0.0508 0.2604
Loa Loa (eye worm) TK/FER protein kinase 0.0038 0.011 0.0157
Schistosoma mansoni tyrosine kinase 0.0027 0.0027 0.0027
Trypanosoma brucei Flagellum attachment zone protein 20 0.0027 0.0027 0.0137
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0725 0.5179 0.7445
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0027 0.0027 0.0137
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Entamoeba histolytica cyclin, putative 0.0035 0.0087 0.0441
Brugia malayi Immunoglobulin I-set domain containing protein 0.0035 0.0084 0.0138
Loa Loa (eye worm) hypothetical protein 0.0027 0.0027 0.0038
Entamoeba histolytica tyrosine kinase, putative 0.0027 0.0027 0.0137
Brugia malayi SH2 domain containing protein 0.0038 0.011 0.0181
Schistosoma mansoni kinase 0.0415 0.2891 0.2891
Schistosoma mansoni tyrosine kinase 0.0027 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0041 0.0132 0.0189
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0282 0.0284
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0027 0.0027 0.0137
Toxoplasma gondii aldehyde dehydrogenase 0.0061 0.0282 0.177
Entamoeba histolytica hypothetical protein 0.0026 0.0018 0.0087
Brugia malayi bone morphogenetic protein type 1 receptor 0.0027 0.0027 0.0044
Schistosoma mansoni cell adhesion molecule 0.0026 0.0023 0.0023
Echinococcus multilocularis activin receptor type 0.0035 0.0086 0.0086
Echinococcus granulosus retinal guanylyl cyclase 2 0.0027 0.0027 0.0027
Echinococcus multilocularis cyclins 0.0035 0.0087 0.0087
Echinococcus granulosus N acetylglucosaminyl phosphatidylinositol 0.0045 0.0162 0.0161
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0035 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0078 0.0406 0.0583
Onchocerca volvulus 0.0027 0.0027 0.0021
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Entamoeba histolytica N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase, putative 0.0045 0.0162 0.0829
Entamoeba histolytica tyrosine kinase, putative 0.0027 0.0027 0.0137
Echinococcus granulosus tyrosine kinase 0.0027 0.0027 0.0027
Schistosoma mansoni tyrosine kinase 0.0027 0.0027 0.0027
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0038 0.011 0.011
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Loa Loa (eye worm) TK protein kinase 0.0027 0.0027 0.0038
Loa Loa (eye worm) hypothetical protein 0.0062 0.0284 0.0408
Loa Loa (eye worm) TK protein kinase 0.0027 0.0027 0.0038
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0027 0.0027 0.0038
Loa Loa (eye worm) hypothetical protein 0.0038 0.011 0.0157
Schistosoma mansoni tyrosine kinase 0.0027 0.0027 0.0027
Brugia malayi GCC2 and GCC3 family protein 0.0026 0.0018 0.0028
Schistosoma mansoni cell adhesion molecule 0.0035 0.0084 0.0084
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0052 0.0052
Plasmodium falciparum tyrosine kinase-like protein 0.0027 0.0027 0.0065
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Brugia malayi GCC2 and GCC3 family protein 0.0026 0.0018 0.0028
Loa Loa (eye worm) hypothetical protein 0.0035 0.0084 0.012
Brugia malayi ephrin receptor 1 precursor 0.0078 0.0401 0.0663
Brugia malayi Raf kinase 0.0027 0.0027 0.0044
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0734 0.5245 0.5245
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0052 0.0052
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0107 0.0615 0.0615
Entamoeba histolytica protein kinase, putative 0.0027 0.0027 0.0137
Entamoeba histolytica PH domain containing protein kinase, putative 0.0052 0.0215 0.1103
Entamoeba histolytica serine/threonine kinase, putative 0.0027 0.0027 0.0137
Echinococcus granulosus twitchin 0.009 0.0496 0.0495
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0049 0.0191 0.019
Brugia malayi Casein kinase II, alpha chain 0.014 0.0858 0.1421
Trichomonas vaginalis AGC family protein kinase 0.0228 0.1514 0.7767
Trypanosoma cruzi protein kinase, putative 0.0027 0.0027 0.0137
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0107 0.0615 0.0615
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0027 0.0027 0.0027
Entamoeba histolytica protein kinase, putative 0.0027 0.0027 0.0137
Trichomonas vaginalis CMGC family protein kinase 0.014 0.0858 0.4401
Trichomonas vaginalis CAMK family protein kinase 0.0287 0.1949 1
Schistosoma mansoni serine/threonine protein kinase 0.0027 0.0027 0.0027
Trichomonas vaginalis AGC family protein kinase 0.0228 0.1514 0.7767
Giardia lamblia Kinase 0.0027 0.0027 0.0137
Entamoeba histolytica protein kinase, putative 0.0027 0.0027 0.0137
Loa Loa (eye worm) TK protein kinase 0.0027 0.0027 0.0038
Trichomonas vaginalis cyclins, putative 0.0035 0.0087 0.0441
Echinococcus multilocularis G2:mitotic specific cyclin B3 0.0035 0.0087 0.0087
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0027 0.0027 0.0137
Toxoplasma gondii hypothetical protein 0.0027 0.0024 0.0045
Brugia malayi Protein kinase domain containing protein 0.0528 0.3728 0.6174
Loa Loa (eye worm) hypothetical protein 0.0035 0.0084 0.012
Echinococcus granulosus nephrin 0.0026 0.0023 0.0022
Loa Loa (eye worm) hypothetical protein 0.0027 0.0027 0.0038
Plasmodium vivax N-acetylglucosaminylphosphatidylinositol deacetylase, putative 0.0045 0.0162 0.0966
Schistosoma mansoni serine/threonine protein kinase 0.0029 0.004 0.004
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0092 0.0508 0.3278
Schistosoma mansoni serine/threonine RGC 0.0027 0.0027 0.0027
Echinococcus granulosus tyrosine protein kinase Fyn 0.0107 0.0615 0.0614
Schistosoma mansoni serine/threonine protein kinase 0.0092 0.0508 0.0508
Echinococcus granulosus tyrosine protein kinase HCK 0.0084 0.0451 0.045
Entamoeba histolytica hypothetical protein 0.0027 0.0027 0.0137
Plasmodium falciparum cyclin 0.0035 0.0087 0.0461
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0035 0.0084 0.0144
Schistosoma mansoni tyrosine kinase 0.0027 0.0027 0.0027
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0061 0.0282 0.0294
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0027 0.0027 0.0137
Schistosoma mansoni tyrosine kinase 0.0543 0.3834 0.3834
Echinococcus granulosus receptor type guanylyl cyclase 0.0027 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0027 0.0027 0.0038
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0107 0.0615 0.0615
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0046 0.0166 0.0166
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.0035 0.0087 0.0441
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0049 0.0191 0.0191
Brugia malayi Immunoglobulin I-set domain containing protein 0.0042 0.0139 0.023
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Echinococcus multilocularis 0.0249 0.1667 0.1667
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Brugia malayi Furin-like cysteine rich region family protein 0.0841 0.6038 1
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Echinococcus multilocularis natriuretic peptide receptor 1 0.0027 0.0027 0.0027
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0061 0.0282 0.0282
Schistosoma mansoni protein kinase 0.0027 0.0027 0.0027
Schistosoma mansoni cyclin B3 0.0035 0.0087 0.0087
Trichomonas vaginalis protein kinase atn1, putative 0.0027 0.0027 0.0137
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0027 0.0027 0.0027
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Echinococcus multilocularis protein kinase 0.0027 0.0027 0.0027
Entamoeba histolytica protein kinase, putative 0.0027 0.0027 0.0137
Loa Loa (eye worm) AGC/NDR protein kinase 0.0029 0.004 0.0056
Brugia malayi hypothetical protein 0.0182 0.1175 0.1946
Entamoeba histolytica protein kinase, putative 0.0027 0.0027 0.0137
Schistosoma mansoni terminal deoxycytidyl transferase 0.0023 0.0001 0.0001
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Onchocerca volvulus 0.0034 0.008 0.0134
Echinococcus multilocularis roundabout 2 0.0046 0.0166 0.0166
Plasmodium vivax tyrosine kinase-like protein, putative 0.0027 0.0027 0.0065
Trichomonas vaginalis AGC family protein kinase 0.0073 0.0367 0.1882
Trichomonas vaginalis CMGC family protein kinase 0.014 0.0858 0.4401
Loa Loa (eye worm) projectin 0.0026 0.0023 0.0032
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0027 0.0027 0.0027
Trichomonas vaginalis AGC family protein kinase 0.0027 0.0027 0.0137
Entamoeba histolytica ankyrin repeat protein 0.0027 0.0027 0.0137
Echinococcus multilocularis activated cdc42 kinase 1 0.0027 0.0027 0.0027
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0027 0.0027 0.0038
Echinococcus granulosus cyclin dependent kinase 1 0.0092 0.0508 0.0508
Toxoplasma gondii AGC kinase 0.0069 0.0338 0.2139
Trypanosoma cruzi Protein kinase B 0.0052 0.0215 0.1103
Echinococcus granulosus epidermal growth factor receptor 0.057 0.4032 0.4032
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0029 0.004 0.0056
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0029 0.004 0.0056
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0048 0.0186 0.0186
Trichomonas vaginalis AGC family protein kinase 0.0228 0.1514 0.7767
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0035 0.0086 0.044
Loa Loa (eye worm) hypothetical protein 0.0026 0.0018 0.0024
Plasmodium falciparum protein kinase, putative 0.0035 0.0086 0.046
Echinococcus multilocularis serine threonine protein kinase 0.0029 0.004 0.004
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0042 0.0139 0.0139
Brugia malayi Protein kinase domain containing protein 0.0038 0.011 0.0181
Loa Loa (eye worm) hypothetical protein 0.0027 0.0027 0.0038
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0046 0.0166 0.0166
Schistosoma mansoni tyrosine kinase 0.0027 0.0027 0.0027
Echinococcus granulosus serine:threonine protein kinase N2 0.0029 0.004 0.0039
Schistosoma mansoni protein kinase 0.0027 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0035 0.0084 0.012
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0027 0.0027 0.0027
Entamoeba histolytica cysteine-rich surface protein, putative 0.0026 0.0018 0.0087
Schistosoma mansoni tyrosine kinase 0.0723 0.5163 0.5163
Onchocerca volvulus 0.0026 0.0023 0.0012
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0027 0.0027 0.0027
Brugia malayi Protein kinase domain containing protein 0.0027 0.0027 0.0044
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0052 0.0052
Loa Loa (eye worm) TK/FER protein kinase 0.0038 0.011 0.0157
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0227 0.1504 0.1504
Echinococcus granulosus protein kinase 0.0027 0.0027 0.0027
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0027 0.0027 0.0027
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.006 0.0273 0.0451
Schistosoma mansoni lipoxygenase 0.0054 0.023 0.023
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0282 0.0282
Entamoeba histolytica protein kinase domain containing protein 0.0027 0.0027 0.0137
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Loa Loa (eye worm) SRC-1 0.0107 0.0615 0.0883
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0027 0.0027 0.0137
Trichomonas vaginalis AGC family protein kinase 0.0228 0.1514 0.7767
Brugia malayi protein-tyrosine kinase 0.0096 0.0534 0.0883
Onchocerca volvulus 0.003 0.0052 0.0074
Schistosoma mansoni protein kinase 0.0027 0.0027 0.0027
Onchocerca volvulus 0.0038 0.011 0.02
Brugia malayi Hr1 repeat family protein 0.0029 0.004 0.0065
Schistosoma mansoni serine/threonine-protein kinase 0.0052 0.0215 0.0215
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0067 0.0324 0.0324
Echinococcus granulosus tyrosine protein kinase Fyn 0.0107 0.0615 0.0614
Loa Loa (eye worm) CAMK/CAMKL/NUAK protein kinase 0.0966 0.6956 1
Entamoeba histolytica protein kinase domain containing protein 0.0027 0.0027 0.0137
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0052 0.0229
Entamoeba histolytica hypothetical protein 0.0027 0.0027 0.0137
Schistosoma mansoni serine/threonine protein kinase 0.0029 0.004 0.004
Trichomonas vaginalis AGC family protein kinase 0.0033 0.007 0.0354
Entamoeba histolytica protein kinase domain containing protein 0.0027 0.0027 0.0137
Giardia lamblia Cyclin A 0.0035 0.0087 0.0441
Echinococcus multilocularis cyclins 0.0035 0.0087 0.0087
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0067 0.0324 0.0324
Echinococcus multilocularis Glutaredoxin protein 5 0.004 0.0126 0.0126
Entamoeba histolytica tyrosine kinase, putative 0.0027 0.0027 0.0137
Loa Loa (eye worm) hypothetical protein 0.0026 0.0023 0.0032
Entamoeba histolytica tyrosine kinase, putative 0.0027 0.0027 0.0137
Echinococcus multilocularis tyrosine protein kinase csk 0.0027 0.0027 0.0027
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0027 0.0027 0.0137
Echinococcus granulosus Immunoglobulin 0.0067 0.0324 0.0324
Onchocerca volvulus 0.0034 0.0082 0.0139
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0027 0.0027 0.0137
Brugia malayi Immunoglobulin I-set domain containing protein 0.0034 0.0082 0.0135
Brugia malayi Protein kinase domain containing protein 0.0038 0.011 0.0181
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Brugia malayi serine/threonine kinase 12 0.0228 0.1514 0.2507
Brugia malayi Immunoglobulin I-set domain containing protein 0.0026 0.0023 0.0037
Echinococcus granulosus aurora kinase A 0.0228 0.1514 0.1513
Trypanosoma cruzi cdc2-related kinase 3 0.0092 0.0508 0.2604
Loa Loa (eye worm) hypothetical protein 0.0035 0.0087 0.0124
Schistosoma mansoni serine/threonine kinase 0.0029 0.004 0.004
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0052 0.0051
Schistosoma mansoni cell adhesion molecule 0.0046 0.0166 0.0166
Trypanosoma brucei aurora B kinase 0.0228 0.1514 0.7767
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0046 0.0166 0.0166
Echinococcus multilocularis aurora kinase A 0.0228 0.1514 0.1514
Echinococcus granulosus protein kinase c epsilon type 0.0029 0.004 0.0039
Brugia malayi Immunoglobulin I-set domain containing protein 0.0026 0.0023 0.0037
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Trypanosoma cruzi polo-like protein kinase, putative 0.0287 0.1949 1
Schistosoma mansoni protein kinase 0.0027 0.0027 0.0027
Brugia malayi Cyclin, N-terminal domain containing protein 0.0035 0.0087 0.0142
Brugia malayi hypothetical protein 0.0027 0.0027 0.0044
Entamoeba histolytica tyrosine kinase, putative 0.0027 0.0027 0.0137
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0107 0.0615 0.0615
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0027 0.0027 0.0137
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0046 0.0166 0.0166
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0061 0.0282 0.0282
Entamoeba histolytica protein kinase, putative 0.0029 0.004 0.0201
Brugia malayi Protein kinase domain containing protein 0.0038 0.011 0.0181
Entamoeba histolytica protein kinase, putative 0.0027 0.0027 0.0137
Trypanosoma cruzi polo-like protein kinase, putative 0.0287 0.1949 1
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0029 0.004 0.0039
Trichomonas vaginalis cyclins, putative 0.0035 0.0087 0.0441
Brugia malayi Calcitonin receptor-like protein seb-1 0.006 0.0273 0.0451
Loa Loa (eye worm) hypothetical protein 0.0281 0.1903 0.2736
Echinococcus multilocularis tyrosine kinase 0.0038 0.011 0.011
Loa Loa (eye worm) TK/ROR protein kinase 0.0042 0.0139 0.02
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0027 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0027 0.0027 0.0038
Giardia lamblia Hypothetical protein 0.0035 0.0087 0.0441
Echinococcus granulosus tyrosine protein kinase Fyn 0.0107 0.0615 0.0614
Entamoeba histolytica protein kinase domain containing protein 0.0027 0.0027 0.0137
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0027 0.0031 0.0044
Echinococcus multilocularis neuroglian 0.0082 0.0437 0.0437
Entamoeba histolytica protein kinase domain containing protein 0.0027 0.0027 0.0137
Echinococcus multilocularis roundabout 2 0.0113 0.0662 0.0662
Entamoeba histolytica protein kinase domain containing protein 0.0027 0.0027 0.0137
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0027 0.0027 0.0137
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0027 0.0137
Entamoeba histolytica protein kinase, putative 0.0073 0.0367 0.1882
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0027 0.0027 0.0027
Brugia malayi Immunoglobulin I-set domain containing protein 0.0031 0.0054 0.0088
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0027 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.003 0.0052 0.0074
Schistosoma mansoni tyrosine kinase 0.0723 0.5163 0.5163
Loa Loa (eye worm) hypothetical protein 0.0026 0.0018 0.0024
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0027 0.0027 0.0137
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Loa Loa (eye worm) TK/FER protein kinase 0.0027 0.0027 0.0038
Entamoeba histolytica casein kinase, putative 0.014 0.0858 0.4401
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.014 0.0858 0.1233
Loa Loa (eye worm) hypothetical protein 0.0027 0.0027 0.0038
Schistosoma mansoni tyrosine kinase 0.0027 0.0027 0.0027
Echinococcus granulosus defective proboscis extension response 0.0067 0.0324 0.0324
Brugia malayi Protein kinase domain containing protein 0.0027 0.0027 0.0044
Entamoeba histolytica serine/threonine kinase, putative 0.0027 0.0027 0.0137
Echinococcus granulosus tyrosine protein kinase Src42A 0.0107 0.0615 0.0614
Brugia malayi GCC2 and GCC3 family protein 0.0026 0.0018 0.0028
Entamoeba histolytica protein kinase domain containing protein 0.014 0.0858 0.4401
Brugia malayi Protein kinase domain containing protein 0.0027 0.0027 0.0044
Giardia lamblia Kinase, CMGC CK2 0.014 0.0858 0.4401
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Echinococcus granulosus roundabout 2 0.0046 0.0166 0.0166
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Leishmania major protein kinase, putative 0.0035 0.0086 0.044
Trichomonas vaginalis CMGC family protein kinase 0.014 0.0858 0.4401
Echinococcus multilocularis protein kinase c iota type 0.0029 0.004 0.004
Entamoeba histolytica hypothetical protein 0.0027 0.0027 0.0137
Brugia malayi Pre-SET motif family protein 0.0211 0.1384 0.2292
Schistosoma mansoni plexin 0.0034 0.008 0.008
Entamoeba histolytica protein kinase, putative 0.0228 0.1514 0.7767
Loa Loa (eye worm) TK/FER protein kinase 0.0027 0.0027 0.0038
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0048 0.0186 0.1124
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0027 0.0137
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0023 0.0001 0.0001
Brugia malayi Fibronectin type III domain containing protein 0.0078 0.0406 0.0672
Brugia malayi Protein kinase domain containing protein 0.0027 0.0027 0.0044
Onchocerca volvulus 0.0027 0.0027 0.0021
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0038 0.011 0.0109
Loa Loa (eye worm) hypothetical protein 0.0034 0.008 0.0114
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0092 0.0508 0.073
Schistosoma mansoni nephrin 0.0046 0.0166 0.0166
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0035 0.0086 0.046
Loa Loa (eye worm) TK/ACK protein kinase 0.0027 0.0027 0.0038
Echinococcus granulosus kinase suppressor of Ras 1 0.0027 0.0027 0.0027
Trichomonas vaginalis cyclin B, putative 0.0035 0.0087 0.0441
Brugia malayi SH2 domain containing protein 0.0038 0.011 0.0181
Schistosoma mansoni tyrosine kinase 0.0107 0.0615 0.0615
Trypanosoma cruzi cyclin, putative 0.0035 0.0087 0.0441
Schistosoma mansoni tyrosine kinase 0.0027 0.0027 0.0027
Entamoeba histolytica receptor protein kinase, putative 0.0027 0.0027 0.0137
Brugia malayi SRC-1 0.0107 0.0615 0.1017
Brugia malayi Immunoglobulin I-set domain containing protein 0.0026 0.0023 0.0037
Trichomonas vaginalis CAMK family protein kinase 0.0027 0.0027 0.0137
Entamoeba histolytica protein kinase, putative 0.0073 0.0367 0.1882
Loa Loa (eye worm) plexin A 0.004 0.0126 0.018
Trichomonas vaginalis cyclins, putative 0.0035 0.0087 0.0441
Loa Loa (eye worm) AGC/AKT protein kinase 0.0073 0.0367 0.0527
Loa Loa (eye worm) TK/FER protein kinase 0.0038 0.011 0.0157
Loa Loa (eye worm) TK protein kinase 0.0084 0.0451 0.0647
Echinococcus granulosus NDR protein kinase 0.0029 0.004 0.0039
Echinococcus multilocularis insulin receptor 0.0723 0.5163 0.5163
Entamoeba histolytica protein kinase domain containing protein 0.0027 0.0027 0.0137
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0052 0.0215 0.1103
Loa Loa (eye worm) TK/FER protein kinase 0.0038 0.011 0.0157
Brugia malayi serine/threonine-protein kinase 6 0.0228 0.1514 0.2507
Onchocerca volvulus 0.0027 0.0027 0.0021
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0029 0.004 0.004
Brugia malayi Protein kinase domain containing protein 0.0027 0.0027 0.0044
Schistosoma mansoni tyrosine kinase 0.0027 0.0027 0.0027
Entamoeba histolytica tyrosine kinase, putative 0.0027 0.0027 0.0137
Echinococcus multilocularis nervana 2 0.004 0.0126 0.0126
Onchocerca volvulus 0.0027 0.0027 0.0021
Loa Loa (eye worm) TK/DDR protein kinase 0.0027 0.0027 0.0038
Echinococcus granulosus cyclins 0.0035 0.0087 0.0086
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0228 0.1514 0.7767
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0027 0.0027 0.0137
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0046 0.0166 0.0238
Toxoplasma gondii protein kinase 0.0027 0.0027 0.0065
Giardia lamblia Kinase, NEK 0.0027 0.0027 0.0137
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Echinococcus granulosus insulin receptor 0.0723 0.5163 0.5163
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0228 0.1514 0.1513
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Toxoplasma gondii CMGC kinase, CK2 family 0.014 0.0858 0.5618
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Echinococcus granulosus fibroblast growth factor receptor 4 0.0027 0.0027 0.0027
Brugia malayi Protein kinase domain containing protein 0.0038 0.011 0.0181
Brugia malayi integrin-linked kinase 0.0027 0.0027 0.0044
Echinococcus multilocularis kinase suppressor of Ras 1 0.0027 0.0027 0.0027
Echinococcus granulosus cyclins 0.0035 0.0087 0.0086
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Schistosoma mansoni tyrosine kinase 0.0038 0.011 0.011
Onchocerca volvulus 0.0027 0.0027 0.0021
Loa Loa (eye worm) TK protein kinase 0.0042 0.0139 0.02
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0107 0.0615 0.0615
Trypanosoma cruzi casein kinase II, putative 0.014 0.0858 0.4401
Onchocerca volvulus 0.0611 0.4341 0.9329
Brugia malayi Protein kinase domain containing protein 0.0027 0.0027 0.0044
Trichomonas vaginalis cyclin B, putative 0.0035 0.0087 0.0441
Entamoeba histolytica protein kinase domain containing protein 0.0035 0.0086 0.044
Entamoeba histolytica tyrosine kinase, putative 0.0027 0.0027 0.0137
Schistosoma mansoni tyrosine kinase 0.0027 0.0027 0.0027
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0027 0.0027 0.0027
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0734 0.5245 0.5245
Loa Loa (eye worm) AUR protein kinase 0.0228 0.1514 0.2176
Brugia malayi Protein kinase domain containing protein 0.0308 0.2102 0.3481
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0027 0.0137
Schistosoma mansoni titin 0.0034 0.0082 0.0082
Brugia malayi C-terminal src kinase protein 1 0.0027 0.0027 0.0044
Loa Loa (eye worm) RGC/RGC protein kinase 0.0027 0.0027 0.0038
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0027 0.0027 0.0027
Entamoeba histolytica protein kinase domain containing protein 0.0027 0.0027 0.0137
Brugia malayi Protein kinase domain containing protein 0.0092 0.0508 0.0841
Schistosoma mansoni microtubule-associated protein tau 0.1378 1 1
Entamoeba histolytica protein kinase, putative 0.0027 0.0027 0.0137
Brugia malayi latrophilin 2 splice variant baaae 0.0041 0.0132 0.0218
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0029 0.004 0.004
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0027 0.0027 0.0137
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.014 0.0858 0.5618
Echinococcus multilocularis expressed protein 0.0378 0.2619 0.2619
Echinococcus multilocularis protein KINase family member (kin 25) 0.0027 0.0027 0.0027
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Entamoeba histolytica protein kinase domain containing protein 0.0027 0.0027 0.0137
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Echinococcus granulosus protein kinase c iota type 0.0029 0.004 0.0039
Loa Loa (eye worm) TK protein kinase 0.0096 0.0534 0.0767
Entamoeba histolytica cyclin family protein 0.0035 0.0087 0.0441
Loa Loa (eye worm) CAMK protein kinase 0.0034 0.0082 0.0117
Loa Loa (eye worm) hypothetical protein 0.0067 0.0324 0.0465
Echinococcus granulosus contactin 0.0046 0.0166 0.0166
Leishmania major N-acetyl-D-acetylglucosaminylphosphatidylinositol deacetylase 0.0045 0.0162 0.0829
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0107 0.0615 0.0615
Schistosoma mansoni N-acetylglucosaminyl-phosphatidylinositol de-n-acetylase 0.0045 0.0162 0.0162
Echinococcus multilocularis tyrosine protein kinase Blk 0.0096 0.0534 0.0534
Brugia malayi Plexin repeat family protein 0.0034 0.008 0.0131
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0027 0.0027 0.0027
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0027 0.0027 0.0137
Trichomonas vaginalis cyclin B3, putative 0.0035 0.0087 0.0441
Loa Loa (eye worm) hypothetical protein 0.0027 0.0027 0.0038
Trichomonas vaginalis CAMK family protein kinase 0.0287 0.1949 1
Entamoeba histolytica protein kinase, putative 0.0027 0.0027 0.0137
Brugia malayi Protein kinase domain containing protein 0.0027 0.0027 0.0044
Loa Loa (eye worm) TK/FER protein kinase 0.0027 0.0027 0.0038
Plasmodium falciparum protein kinase, putative 0.0027 0.0027 0.0065
Schistosoma mansoni serine/threonine protein kinase 0.0027 0.0027 0.0027
Schistosoma mansoni serine/threonine protein kinase 0.0029 0.004 0.004
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0027 0.0027 0.0027
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0096 0.0534 0.0533
Brugia malayi Immunoglobulin I-set domain containing protein 0.0046 0.0166 0.0274
Entamoeba histolytica protein kinase domain containing protein 0.0027 0.0027 0.0137
Loa Loa (eye worm) hypothetical protein 0.0078 0.0406 0.0583
Loa Loa (eye worm) AUR protein kinase 0.0228 0.1514 0.2176
Trypanosoma cruzi N-Acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase, putative 0.0045 0.0162 0.0829
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Schistosoma mansoni cell adhesion molecule 0.0098 0.055 0.055
Echinococcus multilocularis cyclin b3 0.0035 0.0087 0.0087
Schistosoma mansoni protein kinase 0.0192 0.1242 0.1242
Loa Loa (eye worm) RGC/RGC protein kinase 0.0027 0.0027 0.0038
Loa Loa (eye worm) pigment dispersing factor receptor c 0.006 0.0273 0.0391
Loa Loa (eye worm) hypothetical protein 0.0067 0.0324 0.0465
Schistosoma mansoni protein kinase 0.0027 0.0027 0.0027
Loa Loa (eye worm) TK/FER protein kinase 0.0038 0.011 0.0157
Plasmodium falciparum tyrosine kinase-like protein 0.0027 0.0027 0.0065
Trichomonas vaginalis cyclin B, putative 0.0035 0.0087 0.0441
Entamoeba histolytica cell division protein kinase 2, putative 0.0092 0.0508 0.2604
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0048 0.0186 0.1124
Echinococcus multilocularis hemicentin 1 0.0035 0.0084 0.0084
Entamoeba histolytica protein kinase domain containing protein 0.0228 0.1514 0.7767
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0044 0.0043
Schistosoma mansoni serine/threonine protein kinase 0.0027 0.0031 0.0031
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0035 0.0084 0.012
Entamoeba histolytica protein kinase domain containing protein 0.0027 0.0027 0.0137
Echinococcus multilocularis microtubule associated protein 2 0.1378 1 1
Schistosoma mansoni tyrosine kinase 0.0841 0.6038 0.6038
Entamoeba histolytica hypothetical protein 0.0027 0.0027 0.0137
Brugia malayi Immunoglobulin I-set domain containing protein 0.0035 0.0084 0.0138
Schistosoma mansoni ephrin receptor 0.0134 0.082 0.082
Entamoeba histolytica tyrosin kinase, putative 0.0027 0.0027 0.0137
Trichomonas vaginalis STE family protein kinase 0.0027 0.0027 0.0137
Entamoeba histolytica protein kinase, putative 0.0027 0.0027 0.0137
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0038 0.011 0.011
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Schistosoma mansoni protein kinase 0.0192 0.1242 0.1242
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0027 0.0027 0.0137
Echinococcus multilocularis tyrosine kinase 0.0027 0.0027 0.0027
Trichomonas vaginalis CMGC family protein kinase 0.0092 0.0508 0.2604
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0092 0.0508 0.0508
Echinococcus multilocularis dna polymerase kappa 0.0023 0.0001 0.0001
Trypanosoma brucei Casein kinase II 0.014 0.0858 0.4401
Echinococcus multilocularis transfer RNA-Phe 0.0026 0.0023 0.0023
Loa Loa (eye worm) RGC/RGC protein kinase 0.0027 0.0027 0.0038
Onchocerca volvulus Tyrosine kinase homolog 0.0654 0.4652 1
Echinococcus multilocularis cyclin B 0.0035 0.0087 0.0087
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0287 0.1949 0.1949
Echinococcus granulosus tyrosine kinase 0.0038 0.011 0.0109
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Entamoeba histolytica tyrosine kinase, putative 0.0027 0.0027 0.0137
Entamoeba histolytica protein kinase domain containing protein 0.0027 0.0027 0.0137
Echinococcus granulosus cyclin dependent kinase 0.0092 0.0508 0.0508
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0027 0.0027 0.0027
Echinococcus granulosus titin 0.0034 0.0082 0.0081
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0027 0.0027 0.0038
Brugia malayi Cyclin, N-terminal domain containing protein 0.0035 0.0087 0.0142
Trichomonas vaginalis CMGC family protein kinase 0.014 0.0858 0.4401
Trypanosoma cruzi cdc2-related kinase 1 0.0092 0.0508 0.2604
Echinococcus multilocularis tyrosine protein kinase Abl 0.0049 0.0191 0.0191
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0061 0.0282 0.1447
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0027 0.0027 0.0065
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0563 0.2885
Entamoeba histolytica tyrosine kinase, putative 0.0027 0.0027 0.0137
Echinococcus multilocularis cyclin dependent kinase 1 0.0092 0.0508 0.0508
Schistosoma mansoni ephrin receptor 0.0038 0.0109 0.0109
Echinococcus granulosus tyrosine protein kinase ABL1 0.0038 0.011 0.0109
Echinococcus granulosus ephrin type A receptor 4 A 0.016 0.1009 0.1009
Trypanosoma cruzi N-Acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase, putative 0.0045 0.0162 0.0829
Echinococcus granulosus G2:mitotic specific cyclin B3 0.0035 0.0087 0.0086
Trypanosoma brucei N-acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase 0.0045 0.0162 0.0829
Trichomonas vaginalis AGC family protein kinase 0.0029 0.004 0.0201
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0027 0.0027 0.0027
Mycobacterium tuberculosis Conserved hypothetical protein 0.0045 0.0162 0.0168
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0052 0.0052
Echinococcus granulosus tyrosine kinase 0.0096 0.0534 0.0533
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0092 0.0508 0.2604
Schistosoma mansoni serine/threonine protein kinase 0.0228 0.1514 0.1514
Brugia malayi Protein kinase domain containing protein 0.0027 0.0027 0.0044
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Echinococcus granulosus tyrosine protein kinase Src42A 0.0069 0.0335 0.0335
Schistosoma mansoni tyrosine kinase 0.0027 0.0027 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0087 0.0441
Echinococcus granulosus tyrosine protein kinase csk 0.0027 0.0027 0.0027
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Entamoeba histolytica protein kinase, putative 0.0027 0.0027 0.0137
Trichomonas vaginalis cyclin D, putative 0.0035 0.0087 0.0441
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0026 0.0023 0.0032
Entamoeba histolytica cysteine surface protein, putative 0.0027 0.0027 0.0137
Brugia malayi Protein kinase domain containing protein 0.0027 0.0027 0.0044
Echinococcus granulosus titin 0.0034 0.0082 0.0081
Entamoeba histolytica serine/threonine kinase, putative 0.0027 0.0027 0.0137
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0029 0.004 0.0039
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Brugia malayi Protein kinase domain containing protein 0.0027 0.0027 0.0044
Leishmania major hypothetical protein, conserved 0.0027 0.0027 0.0137
Entamoeba histolytica serine/threonine kinase, putative 0.0027 0.0027 0.0137
Schistosoma mansoni tyrosine kinase 0.0027 0.0027 0.0027
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0027 0.0027 0.0021
Echinococcus multilocularis cyclins 0.0035 0.0087 0.0087
Echinococcus multilocularis cyclins 0.0035 0.0087 0.0087
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0027 0.0027 0.0038
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0027 0.0027 0.0137
Onchocerca volvulus 0.0038 0.011 0.02
Entamoeba histolytica hypothetical protein, conserved 0.0027 0.0027 0.0137
Trichomonas vaginalis AGC family protein kinase 0.0073 0.0367 0.1882
Schistosoma mansoni protein kinase 0.0228 0.1514 0.1514
Onchocerca volvulus 0.024 0.1599 0.3413
Trichomonas vaginalis AGC family protein kinase 0.0073 0.0367 0.1882
Brugia malayi Protein kinase domain containing protein 0.0038 0.011 0.0181
Echinococcus multilocularis tyrosine protein kinase pr2 0.0027 0.0027 0.0027
Schistosoma mansoni serine/threonine protein kinase 0.0038 0.0108 0.0108
Echinococcus multilocularis raf serine:threonine protein kinase 0.0027 0.0027 0.0027
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Toxoplasma gondii N-acetylglucosaminylphosphatidylinositol deacetylase 0.0045 0.0162 0.0966
Schistosoma mansoni titin 0.0035 0.0084 0.0084
Loa Loa (eye worm) cyclin domain-containing protein 0.0035 0.0087 0.0124
Echinococcus granulosus tyrosine protein kinase otk 0.0035 0.0084 0.0084
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0027 0.0031 0.005
Leishmania major casein kinase II, putative 0.014 0.0858 0.4401
Echinococcus multilocularis protein tyrosine kinase 0.0522 0.3684 0.3684
Entamoeba histolytica hypothetical protein 0.0027 0.0027 0.0137
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Trichomonas vaginalis set domain proteins, putative 0.024 0.1599 0.8204
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Plasmodium vivax SET domain protein, putative 0.003 0.0052 0.0229
Echinococcus granulosus tyrosine protein kinase Lyn 0.0115 0.0674 0.0673
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0228 0.1514 0.7767
Schistosoma mansoni tyrosine kinase 0.0543 0.3834 0.3834
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0046 0.0166 0.0166
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0027 0.0027 0.0137
Echinococcus granulosus nervana 2 0.004 0.0126 0.0126
Brugia malayi Protein kinase domain containing protein 0.0073 0.0367 0.0608
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0031 0.0054 0.0077
Loa Loa (eye worm) hypothetical protein 0.006 0.0273 0.0391
Echinococcus granulosus hemicentin 1 0.0035 0.0084 0.0084
Echinococcus multilocularis tyrosine protein kinase csk 0.0027 0.0027 0.0027
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0029 0.004 0.0039
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0054 0.023 0.023
Plasmodium falciparum casein kinase 2, alpha subunit 0.014 0.0858 0.5618
Entamoeba histolytica tyrosin kinase, putative 0.0027 0.0027 0.0137
Schistosoma mansoni hypothetical protein 0.0026 0.0018 0.0018
Echinococcus multilocularis Immunoglobulin 0.0067 0.0324 0.0324
Echinococcus multilocularis peroxidasin 0.0035 0.0084 0.0084
Entamoeba histolytica protein kinase domain containing protein 0.0027 0.0027 0.0137
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0107 0.0615 0.0614
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0027 0.0027 0.0027
Brugia malayi Protein kinase domain containing protein 0.0027 0.0027 0.0044
Entamoeba histolytica glucosamine-6-phosphate isomerase, putative 0.0045 0.0162 0.0829
Loa Loa (eye worm) hypothetical protein 0.0026 0.0018 0.0024
Loa Loa (eye worm) hypothetical protein 0.0027 0.0027 0.0038
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0023 0.0001 0.0001
Echinococcus granulosus serine/threonine protein kinase 0.0052 0.0215 0.0215
Onchocerca volvulus 0.0038 0.011 0.02
Giardia lamblia Protein 21.1 0.0027 0.0027 0.0137
Trichomonas vaginalis cyclin D, putative 0.0035 0.0087 0.0441
Trypanosoma brucei cdc2-related kinase 1 0.0092 0.0508 0.2604
Trichomonas vaginalis cyclin B, putative 0.0035 0.0087 0.0441
Entamoeba histolytica protein kinase, putative 0.0228 0.1514 0.7767
Echinococcus multilocularis protein kinase 0.0027 0.0027 0.0027
Echinococcus multilocularis serine:threonine protein kinase 38 0.0029 0.004 0.004
Schistosoma mansoni tyrosine kinase 0.0522 0.3684 0.3684
Brugia malayi Immunoglobulin I-set domain containing protein 0.0035 0.0084 0.0138
Trichomonas vaginalis CMGC family protein kinase 0.0092 0.0508 0.2604
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0228 0.1514 1
Brugia malayi cell division control protein 2 homolog 0.0092 0.0508 0.0841
Plasmodium vivax protein kinase, putative 0.0035 0.009 0.0481
Plasmodium falciparum protein kinase 5 0.0092 0.0508 0.3278
Schistosoma mansoni atypical protein kinase C 0.0029 0.004 0.004
Echinococcus granulosus cyclin dependent kinase 5 0.0092 0.0508 0.0508
Schistosoma mansoni serine/threonine protein kinase 0.0027 0.0031 0.0031
Giardia lamblia CEGP1 protein 0.0026 0.0018 0.0087
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Echinococcus multilocularis cyclin dependent kinase 1 0.0092 0.0508 0.0508
Echinococcus multilocularis tyrosine protein kinase 0.0027 0.0027 0.0027
Echinococcus multilocularis receptor type guanylyl cyclase 0.0027 0.0027 0.0027
Entamoeba histolytica protein kinase, putative 0.0027 0.0027 0.0137
Loa Loa (eye worm) hypothetical protein 0.0046 0.0166 0.0238
Leishmania major cyclin 0.0035 0.0087 0.0441
Schistosoma mansoni roundabout 0.0035 0.0084 0.0084
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0087 0.0468 0.0467
Plasmodium falciparum N-acetylglucosaminylphosphatidylinositol deacetylase, putative 0.0045 0.0162 0.0966
Entamoeba histolytica tyrosine kinase, putative 0.0027 0.0027 0.0137
Entamoeba histolytica tyrosine kinase, putative 0.0027 0.0027 0.0137
Onchocerca volvulus 0.0027 0.0027 0.0021
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0027 0.0027 0.0027
Echinococcus granulosus protein tyrosine kinase 0.0522 0.3684 0.3684
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0069 0.0335 0.0335
Loa Loa (eye worm) hypothetical protein 0.0026 0.0023 0.0032
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Brugia malayi hypothetical protein 0.0078 0.0406 0.0672
Echinococcus multilocularis cyclins 0.0035 0.0087 0.0087
Loa Loa (eye worm) hypothetical protein 0.0107 0.0622 0.0893
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0287 0.1949 0.1949
Schistosoma mansoni cyclins 0.0035 0.0087 0.0087
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0038 0.011 0.0562
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Loa Loa (eye worm) hypothetical protein 0.0026 0.0018 0.0024
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0027 0.0027 0.0044
Entamoeba histolytica tyrosine kinase, putative 0.0027 0.0027 0.0137
Echinococcus granulosus tyrosine protein kinase csk 0.0027 0.0027 0.0027
Entamoeba histolytica tyrosin kinase, putative 0.0033 0.0073 0.0373
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Entamoeba histolytica protein kinase domain containing protein 0.0027 0.0027 0.0137
Echinococcus multilocularis cyclins 0.0035 0.0087 0.0087
Brugia malayi protein kinase C II. 0.0029 0.004 0.0065
Brugia malayi serine/threonine-protein kinase plk-2 0.0287 0.1949 0.3228
Echinococcus granulosus cyclins 0.0035 0.0087 0.0086
Brugia malayi Immunoglobulin I-set domain containing protein 0.0035 0.0084 0.0138
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0027 0.0137
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0027 0.0031 0.0044
Schistosoma mansoni hypothetical protein 0.0026 0.0023 0.0023
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0029 0.004 0.004
Echinococcus granulosus Protein kinase C brain isozyme 0.0029 0.004 0.0039
Schistosoma mansoni titin 0.0026 0.0023 0.0023
Echinococcus multilocularis tyrosine protein kinase csk 0.0027 0.0027 0.0027
Trypanosoma cruzi aurora B kinase, putative 0.0228 0.1514 0.7767
Trichomonas vaginalis AGC family protein kinase 0.0073 0.0367 0.1882
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0192 0.1242 0.1242
Loa Loa (eye worm) TK/CSK protein kinase 0.0027 0.0027 0.0038
Trypanosoma brucei polo-like protein kinase 0.0287 0.1949 1
Echinococcus granulosus activated cdc42 kinase 1 0.0027 0.0027 0.0027
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0027 0.0027 0.0027
Echinococcus multilocularis hemicentin 1 0.0035 0.0084 0.0084
Entamoeba histolytica protein kinase, putative 0.0034 0.0077 0.0391
Trichomonas vaginalis TK family protein kinase 0.0027 0.0027 0.0137
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Echinococcus multilocularis c src tyrosine kinase 0.0049 0.0191 0.0191
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0282 0.0282
Toxoplasma gondii aurora kinase 0.0228 0.1514 1
Echinococcus granulosus tyrosine protein kinase pr2 0.0027 0.0027 0.0027
Echinococcus multilocularis nervana 2 0.004 0.0126 0.0126
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0027 0.0027 0.0044
Brugia malayi Protein kinase domain containing protein 0.0027 0.0027 0.0044
Loa Loa (eye worm) protein kinase domain-containing protein 0.0027 0.0027 0.0038
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0054 0.023 0.0229
Entamoeba histolytica cyclin, putative 0.0035 0.0087 0.0441
Toxoplasma gondii STE kinase 0.0027 0.0027 0.0065
Trichomonas vaginalis AGC family protein kinase 0.0073 0.0367 0.1882
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0054 0.0225 0.0323
Onchocerca volvulus 0.0107 0.0622 0.1303
Onchocerca volvulus 0.0182 0.1175 0.2498
Echinococcus granulosus plexin a4 0.004 0.0126 0.0125
Schistosoma mansoni tyrosine kinase 0.0038 0.011 0.011
Brugia malayi Immunoglobulin I-set domain containing protein 0.0078 0.0406 0.0672
Loa Loa (eye worm) TK protein kinase 0.0027 0.0027 0.0038
Echinococcus granulosus c src tyrosine kinase 0.0049 0.0191 0.019
Trichomonas vaginalis CMGC family protein kinase 0.014 0.0858 0.4401
Trichomonas vaginalis CAMK family protein kinase 0.0287 0.1949 1
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0027 0.0027 0.0027
Schistosoma mansoni protein kinase 0.0027 0.0027 0.0027
Giardia lamblia Kinase, AGC PKA 0.0048 0.0186 0.095
Echinococcus granulosus neuroglian 0.0046 0.0166 0.0166
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.004 0.0126 0.0126
Entamoeba histolytica hypothetical protein 0.0027 0.0027 0.0137
Entamoeba histolytica protein kinase domain containing protein 0.0027 0.0027 0.0137
Echinococcus multilocularis dna polymerase eta 0.0023 0.0001 0.0001
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Schistosoma mansoni cell adhesion molecule 0.0046 0.0166 0.0166
Brugia malayi plexin A 0.004 0.0126 0.0207
Loa Loa (eye worm) TK/FER protein kinase 0.0038 0.011 0.0157
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Schistosoma mansoni serine/threonine protein kinase 0.0287 0.1949 0.1949
Echinococcus multilocularis endonuclease reverse transcriptase 0.0026 0.0018 0.0018
Trichomonas vaginalis AGC family protein kinase 0.0029 0.004 0.0201
Trichomonas vaginalis cyclin A, putative 0.0035 0.0087 0.0441
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0282 0.0284
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0026 0.0023 0.0032
Echinococcus multilocularis ephrin type A receptor 4 A 0.016 0.1009 0.1009
Entamoeba histolytica protein kinase domain containing protein 0.0027 0.0027 0.0137
Giardia lamblia Aurora kinase 0.0228 0.1514 0.7767
Entamoeba histolytica hypothetical protein, conserved 0.0026 0.0018 0.0087
Echinococcus granulosus protein kinase C gamma type 0.0029 0.004 0.0039
Echinococcus granulosus retinal guanylyl cyclase 2 0.0027 0.0027 0.0027
Brugia malayi Protein kinase domain containing protein 0.0027 0.0027 0.0044
Brugia malayi Guanylyl cyclase protein 23 0.0027 0.0027 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0027 0.0137
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0052 0.0052
Brugia malayi Protein kinase domain containing protein 0.0027 0.0027 0.0044
Entamoeba histolytica protein kinase, putative 0.0027 0.0027 0.0137
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0049 0.0191 0.0191
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0048 0.0186 0.0185
Entamoeba histolytica protein kinase, putative 0.0069 0.0338 0.1729
Echinococcus granulosus tyrosine protein kinase Blk 0.0096 0.0534 0.0533
Echinococcus granulosus Down syndrome cell adhesion molecule 0.0031 0.0054 0.0053
Trypanosoma cruzi cyclin 6, putative 0.0035 0.0087 0.0441
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0092 0.0508 0.073
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.057 0.4032 0.4032
Echinococcus granulosus Glutaredoxin protein 5 0.004 0.0126 0.0126
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0027 0.0027 0.0044
Giardia lamblia Hypothetical protein 0.0026 0.0018 0.0087
Loa Loa (eye worm) TK/ABL protein kinase 0.0038 0.011 0.0157
Echinococcus multilocularis transfer RNA-Thr 0.0027 0.0027 0.0027
Trichomonas vaginalis CMGC family protein kinase 0.014 0.0858 0.4401
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Plasmodium vivax protein kinase Crk2 0.0092 0.0508 0.3278
Schistosoma mansoni serine/threonine protein kinase 0.0092 0.0508 0.0508
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0035 0.0086 0.044
Schistosoma mansoni cell adhesion molecule 0.0026 0.0023 0.0023
Echinococcus multilocularis cyclin dependent kinase 5 0.0092 0.0508 0.0508
Echinococcus multilocularis titin 0.0034 0.0082 0.0082
Schistosoma mansoni hypothetical protein 0.0041 0.0132 0.0132
Echinococcus granulosus endonuclease reverse transcriptase 0.0026 0.0018 0.0017
Schistosoma mansoni hypothetical protein 0.0027 0.0027 0.0027
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Schistosoma mansoni protein tyrosine kinase 0.0027 0.0027 0.0027
Echinococcus granulosus tyrosine protein kinase shark 0.0038 0.011 0.0109
Plasmodium vivax tyrosine kinase-like protein, putative 0.0027 0.0027 0.0065
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Onchocerca volvulus 0.0027 0.0027 0.0021
Onchocerca volvulus 0.0038 0.011 0.02
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0027 0.0027 0.0044
Loa Loa (eye worm) hypothetical protein 0.0087 0.0468 0.0671
Entamoeba histolytica hypothetical protein 0.0027 0.0027 0.0137
Schistosoma mansoni protein kinase 0.014 0.0858 0.0858
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0027 0.0027 0.0137
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0092 0.0508 0.073
Brugia malayi Immunoglobulin I-set domain containing protein 0.0026 0.0023 0.0037
Schistosoma mansoni myosin-binding protein-related 0.0026 0.0023 0.0023
Echinococcus multilocularis epidermal growth factor receptor 0.0841 0.6038 0.6038
Trichomonas vaginalis AGC family protein kinase 0.0029 0.004 0.0201
Trypanosoma brucei Pseudokinase, putative 0.0027 0.0027 0.0137
Onchocerca volvulus 0.0038 0.011 0.02
Loa Loa (eye worm) serine/threonine protein kinase 0.0027 0.0027 0.0038
Loa Loa (eye worm) TK/INSR protein kinase 0.0723 0.5163 0.7422
Loa Loa (eye worm) hypothetical protein 0.0035 0.0084 0.012
Schistosoma mansoni serine/threonine protein kinase 0.0027 0.0031 0.0031
Entamoeba histolytica tyrosine kinase, putative 0.0027 0.0027 0.0137
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0092 0.0508 0.2604
Loa Loa (eye worm) hypothetical protein 0.0027 0.0027 0.0038
Entamoeba histolytica protein kinase, putative 0.0084 0.0451 0.2311
Loa Loa (eye worm) hypothetical protein 0.0029 0.004 0.0056
Trichomonas vaginalis CAMK family protein kinase 0.0287 0.1949 1
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0287 0.1949 0.2801
Loa Loa (eye worm) hypothetical protein 0.0084 0.0449 0.0645
Echinococcus granulosus cyclin b3 0.0035 0.0087 0.0086
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0027 0.0027 0.0044
Plasmodium falciparum serine/threonine protein kinase, putative 0.0228 0.1514 1
Trichomonas vaginalis CAMK family protein kinase 0.0287 0.1949 1
Schistosoma mansoni tyrosine kinase 0.0027 0.0027 0.0027
Brugia malayi Uncharacterized LmbE-like protein, COG2120 containing protein 0.0045 0.0162 0.0267
Brugia malayi Protein kinase domain containing protein 0.0029 0.004 0.0065
Schistosoma mansoni tyrosine protein kinase 0.0027 0.0027 0.0027
Echinococcus multilocularis beta adrenergic receptor kinase 0.0027 0.0031 0.0031
Echinococcus multilocularis epidermal growth factor receptor 0.057 0.4032 0.4032
Loa Loa (eye worm) AUR protein kinase 0.0228 0.1514 0.2176
Brugia malayi Immunoglobulin I-set domain containing protein 0.0035 0.0084 0.0138
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0027 0.0027 0.0038
Schistosoma mansoni tyrosine kinase 0.057 0.4032 0.4032
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Schistosoma mansoni cyclin B 0.0035 0.0087 0.0087
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0027 0.0027 0.0038
Trypanosoma cruzi cyclin, putative 0.0035 0.0087 0.0441
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Loa Loa (eye worm) TK/RYK protein kinase 0.0027 0.0027 0.0038
Brugia malayi Protein kinase domain containing protein 0.0027 0.0027 0.0044
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0979 0.7055 0.7055
Mycobacterium tuberculosis Mycothiol conjugate amidase Mca (mycothiol S-conjugate amidase) 0.1324 0.96 1
Echinococcus granulosus beta-adrenergic receptor kinase 0.0027 0.0031 0.003
Echinococcus multilocularis tyrosine protein kinase HCK 0.0084 0.0451 0.0451
Echinococcus multilocularis heat shock protein 70 0.0027 0.0027 0.0027
Onchocerca volvulus 0.0035 0.0087 0.0149
Giardia lamblia Kinase, NEK 0.0027 0.0027 0.0137
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Entamoeba histolytica protein kinase, putative 0.0027 0.0027 0.0137
Entamoeba histolytica protein kinase, putative 0.0027 0.0027 0.0137
Trypanosoma cruzi CYC2-like cyclin, putative 0.0035 0.0087 0.0441
Loa Loa (eye worm) TK/FER protein kinase 0.0027 0.0027 0.0038
Loa Loa (eye worm) TK/ALK protein kinase 0.0027 0.0027 0.0038
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Brugia malayi Tyrosine-protein kinase PR2 0.0027 0.0027 0.0044
Trichomonas vaginalis AGC family protein kinase 0.0073 0.0367 0.1882
Echinococcus granulosus nervana 2 0.004 0.0126 0.0126
Entamoeba histolytica protein kinase, putative 0.0027 0.0027 0.0137
Entamoeba histolytica cyclin family protein 0.0035 0.0087 0.0441
Entamoeba histolytica hypothetical protein 0.0027 0.0027 0.0137
Loa Loa (eye worm) hypothetical protein 0.0035 0.0087 0.0124
Echinococcus granulosus cyclins 0.0035 0.0087 0.0086
Entamoeba histolytica PH domain containing protein kinase, putative 0.0052 0.0215 0.1103
Loa Loa (eye worm) TK/FER protein kinase 0.0027 0.0027 0.0038
Loa Loa (eye worm) TK/Met protein kinase 0.0027 0.0027 0.0038
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0069 0.0338 0.0484
Schistosoma mansoni tyrosine kinase 0.0027 0.0027 0.0027
Schistosoma mansoni tyrosine kinase 0.0049 0.0191 0.0191
Entamoeba histolytica protein kinase, putative 0.0027 0.0027 0.0137
Echinococcus multilocularis cyclin dependent kinase 0.0092 0.0508 0.0508
Brugia malayi Protein kinase domain containing protein 0.0723 0.5163 0.8551
Echinococcus granulosus neuroglian 0.0082 0.0437 0.0436
Onchocerca volvulus 0.0027 0.0027 0.0021
Entamoeba histolytica protein kinase , putative 0.0228 0.1514 0.7767
Trichomonas vaginalis cyclins, putative 0.0035 0.0087 0.0441
Schistosoma mansoni serine/threonine protein kinase 0.0027 0.0027 0.0027
Mycobacterium tuberculosis N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase MshB (GlcNAc-Ins deacetylase) 0.0045 0.0162 0.0168
Giardia lamblia Kinase, CMGC CDK 0.0092 0.0508 0.2604
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0027 0.0137
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0029 0.004 0.0056
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Schistosoma mansoni DNA polymerase eta 0.0023 0.0001 0.0001
Leishmania major protein kinase, putative 0.0027 0.0027 0.0137
Brugia malayi Protein kinase domain containing protein 0.0027 0.0027 0.0044
Echinococcus multilocularis FL cytokine receptor 0.0027 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0035 0.0084 0.012
Brugia malayi Tyrosine-protein kinase abl-1 0.0049 0.0191 0.0315
Loa Loa (eye worm) AGC/PKN protein kinase 0.0029 0.004 0.0056
Loa Loa (eye worm) hypothetical protein 0.0078 0.0406 0.0583
Echinococcus granulosus retinal guanylyl cyclase 2 0.0027 0.0027 0.0027
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0027 0.0027 0.0027
Brugia malayi Cyclin, N-terminal domain containing protein 0.0035 0.0087 0.0142
Trichomonas vaginalis cyclin B, putative 0.0035 0.0087 0.0441
Echinococcus multilocularis roundabout 2 0.0046 0.0166 0.0166
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0027 0.0027 0.0137
Giardia lamblia Kinase, CMGC CDK 0.0092 0.0508 0.2604
Echinococcus multilocularis Immunoglobulin 0.0067 0.0324 0.0324
Trypanosoma brucei mitotic cyclin 6 0.0035 0.0087 0.0441
Plasmodium vivax unspecified product 0.014 0.0858 0.5618
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0192 0.1242 0.1242
Entamoeba histolytica protein kinase 2, putative 0.0048 0.0186 0.095
Schistosoma mansoni tyrosine kinase 0.057 0.4032 0.4032
Entamoeba histolytica hypothetical protein 0.0026 0.0018 0.0087
Echinococcus multilocularis rac serine:threonine kinase 0.0052 0.0215 0.0215
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0027 0.0027 0.0021
Brugia malayi protein unc-22 0.0034 0.0082 0.0135
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0026 0.0023 0.0032
Entamoeba histolytica hypothetical protein 0.0027 0.0027 0.0137
Echinococcus multilocularis tyrosine protein kinase otk 0.0035 0.0084 0.0084
Brugia malayi Peroxidasin 0.0035 0.0084 0.0138
Echinococcus granulosus casein kinase ii subunit alpha 0.014 0.0858 0.0858
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0227 0.1504 0.1504
Trichomonas vaginalis TKL family protein kinase 0.0027 0.0027 0.0137
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0067 0.0324 0.0324
Schistosoma mansoni tyrosine kinase 0.0062 0.0283 0.0283
Entamoeba histolytica protein kinase domain containing protein 0.0027 0.0027 0.0137
Entamoeba histolytica tyrosin kinase, putative 0.0027 0.0027 0.0137
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0035 0.0086 0.044
Brugia malayi Immunoglobulin I-set domain containing protein 0.0046 0.0166 0.0274
Mycobacterium ulcerans mycothiol conjugate amidase Mca 0.1369 0.9933 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0027 0.0027 0.0137
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0287 0.1949 1
Loa Loa (eye worm) TK/FER protein kinase 0.0038 0.011 0.0157
Schistosoma mansoni serine/threonine protein kinase 0.0034 0.0082 0.0082
Schistosoma mansoni protein kinase 0.0027 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0027 0.0027 0.0038
Entamoeba histolytica tyrosine kinase, putative 0.0027 0.0027 0.0137
Schistosoma mansoni neuroglian 0.0046 0.0166 0.0166
Brugia malayi Protein kinase domain containing protein 0.0029 0.004 0.0065
Echinococcus multilocularis Down syndrome cell adhesion molecule 0.0031 0.0054 0.0054
Entamoeba histolytica serine/threonine kinase, putative 0.0027 0.0027 0.0137

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 3.9811 uM PubChem BioAssay. Inhibitors of USP1/UAF1: Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 7.9433 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Vif-A3F Interactions: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 10 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 12.5893 uM PubChem BioAssay. qHTS of alpha-syn Inhibitors. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 14.575 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] ChEMBL. No reference
Potency (functional) 17.7828 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference
Potency (functional) 20.5962 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference
Potency (functional) 28.1838 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Eta. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588636] ChEMBL. No reference
Potency (functional) 35.4813 uM PubChem BioAssay. qHTS of TDP-43 Inhibitors. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 47.7548 uM PubChem BioAssay. qHTS Assay to Find Inhibitors of Pin1. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 50.1187 uM PUBCHEM_BIOASSAY: qHTS assay for re-activators of p53 using a Luc reporter. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504709] ChEMBL. No reference
Potency (functional) 56.2341 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of JMJD2A-Tudor Domain. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504402] ChEMBL. No reference
Potency (functional) 56.2341 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488771] ChEMBL. No reference
Potency (functional) 56.2341 uM PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 79.4328 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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