Detailed information for compound 1514288

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 445.532 | Formula: C22H27N3O5S
  • H donors: 0 H acceptors: 3 LogP: 1.68 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc(cc1)CSC1=NC[C@H]2N1[C@@](CC)(C(=O)OC)[C@@H]1[C@H]2C(=O)N(C1=O)CC
  • InChi: 1S/C22H27N3O5S/c1-5-22(20(28)30-4)17-16(18(26)24(6-2)19(17)27)15-11-23-21(25(15)22)31-12-13-7-9-14(29-3)10-8-13/h7-10,15-17H,5-6,11-12H2,1-4H3/t15-,16+,17-,22-/m1/s1
  • InChiKey: KVUQNSFWNIJXEZ-MPWIWIEXSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0065 0.0635 0.1256
Brugia malayi Nuclear hormone receptor family member nhr-1 0.003 0.018 0.0357
Leishmania major hypothetical protein, conserved 0.0035 0.0251 0.0313
Echinococcus granulosus fetal alzheimer antigen falz 0.0044 0.0367 0.0441
Echinococcus granulosus thioredoxin glutathione reductase 0.0131 0.1479 0.1776
Schistosoma mansoni 6-phosphofructokinase 0.0107 0.1165 0.2265
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0425 0.0841
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0251 0.0193
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0289 0.0274
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0331 0.4044 0.4798
Echinococcus multilocularis citrate lyase subunit beta protein 0.0048 0.0417 0.0417
Brugia malayi hypothetical protein 0.0148 0.1699 0.336
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0045 0.0378 0.0563
Echinococcus granulosus lamin 0.0026 0.0137 0.0165
Echinococcus granulosus chromobox protein 1 0.0068 0.0674 0.081
Toxoplasma gondii Hsp90 domain-containing protein 0.0026 0.0134 0.0306
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0044 0.0367 0.0714
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.012 0.1332 0.1332
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0131 0.1472 0.1676
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.003 0.018 0.0351
Loa Loa (eye worm) hypothetical protein 0.0035 0.0251 0.0496
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0137 0.0271
Trypanosoma brucei heat shock protein, putative 0.0064 0.0619 0.1037
Mycobacterium ulcerans 6-phosphofructokinase 0.0107 0.1165 0.1303
Loa Loa (eye worm) hypothetical protein 0.0148 0.1699 0.336
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0051 0.0452 0.0708
Mycobacterium ulcerans aldehyde dehydrogenase 0.012 0.1332 0.1506
Brugia malayi glutathione reductase 0.0131 0.1472 0.2912
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.003 0.018 0.0357
Leishmania major heat shock protein 83-1 0.0064 0.0619 0.1037
Leishmania major heat shock protein 83-1 0.0064 0.0619 0.1037
Trypanosoma cruzi polo-like protein kinase, putative 0.0093 0.0986 0.1691
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.003 0.018 0.018
Onchocerca volvulus Protein ultraspiracle homolog 0.003 0.018 0.0081
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0048 0.0417 0.0561
Schistosoma mansoni jumonji domain containing protein 0.0058 0.0538 0.1046
Leishmania major heat shock protein 83-1 0.0064 0.0619 0.1037
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0241 0.0189
Trypanosoma brucei Heat shock protein 83, putative 0.0064 0.0619 0.1037
Brugia malayi Hsp90 protein 0.0026 0.0134 0.0266
Mycobacterium leprae Probable lipase LipE 0.0035 0.0251 0.0402
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0289 0.0274
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0065 0.0635 0.1235
Leishmania major heat shock protein 83-1 0.0064 0.0619 0.1037
Schistosoma mansoni thyroid hormone receptor 0.003 0.018 0.0351
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0425 0.0841
Brugia malayi heat shock protein 90 0.0064 0.0619 0.1224
Brugia malayi 6-phosphofructokinase 0.0107 0.1165 0.2305
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0059 0.0552 0.1073
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0251 0.0488
Trichomonas vaginalis heat shock protein, putative 0.0064 0.0619 0.0858
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0038 0.0289 0.0274
Schistosoma mansoni chromobox protein 0.0068 0.0674 0.1311
Entamoeba histolytica heat shock protein 90, putative 0.0064 0.0619 0.491
Onchocerca volvulus 0.0026 0.0137 0.0005
Trypanosoma brucei transcription factor BTF3, putative 0.0035 0.0241 0.0294
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0034 0.0229 0.0229
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0045 0.0378 0.0563
Mycobacterium leprae Probable anthranilate phosphoribosyltransferase TrpD 0.0188 0.2206 0.5348
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0251 0.0231
Echinococcus multilocularis chromobox protein 1 0.0068 0.0674 0.0674
Brugia malayi Bromodomain containing protein 0.0076 0.0766 0.1514
Trichomonas vaginalis esterase, putative 0.0035 0.0251 0.0206
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0082 0.0844 0.1669
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0241 0.0189
Mycobacterium ulcerans aldehyde dehydrogenase 0.012 0.1332 0.1506
Brugia malayi beta-lactamase 0.0035 0.0251 0.0496
Plasmodium vivax endoplasmin, putative 0.0064 0.0619 0.3818
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0048 0.0417 0.05
Schistosoma mansoni thyroid hormone receptor 0.003 0.018 0.0351
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0045 0.0378 0.0484
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0019 0.0044 0.0052
Loa Loa (eye worm) hypothetical protein 0.003 0.018 0.0357
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.018 0.0357
Echinococcus multilocularis thioredoxin glutathione reductase 0.0131 0.1479 0.1479
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0058 0.0538 0.0646
Schistosoma mansoni zinc finger protein 0.003 0.0184 0.0359
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0045 0.0378 0.0347
Schistosoma mansoni heat shock protein 0.0064 0.0619 0.1203
Trypanosoma cruzi transcription factor btf3, putative 0.0035 0.0241 0.0212
Mycobacterium ulcerans hypothetical protein 0.0048 0.0417 0.0394
Echinococcus multilocularis thymidine phosphorylase 0.0666 0.8327 0.8327
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0045 0.0378 0.0484
Echinococcus multilocularis thyroid hormone receptor alpha 0.003 0.018 0.018
Brugia malayi Nuclear hormone receptor family member nhr-41 0.003 0.018 0.0357
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.003 0.018 0.0357
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.018 0.018
Leishmania major heat shock protein 83-1 0.0064 0.0619 0.1037
Echinococcus granulosus heat shock protein 90 0.0051 0.0452 0.0543
Onchocerca volvulus 0.0026 0.0137 0.0005
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0167 0.2631
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0045 0.0378 0.0347
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0048 0.0417 0.0394
Mycobacterium tuberculosis Conserved protein 0.0035 0.0251 0.0193
Echinococcus granulosus zinc finger protein 0.0039 0.0293 0.0351
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0674 0.0956
Trypanosoma brucei heat shock protein 84, putative 0.0026 0.0134 0.0083
Loa Loa (eye worm) hypothetical protein 0.0084 0.0875 0.1731
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0045 0.0378 0.7952
Trypanosoma cruzi heat shock protein 85, putative 0.0064 0.0619 0.0962
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0058 0.0538 0.0538
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.018 0.0357
Trypanosoma cruzi ISWI complex protein 0.003 0.0184 0.0099
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0251 0.0206
Loa Loa (eye worm) steroid hormone receptor 0.003 0.018 0.0357
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0045 0.0378 0.0748
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0146 0.002
Loa Loa (eye worm) hypothetical protein 0.0139 0.1585 0.3134
Plasmodium falciparum heat shock protein 90, putative 0.0026 0.0134 0.0306
Loa Loa (eye worm) hypothetical protein 0.0035 0.0251 0.0496
Trypanosoma cruzi transcription factor btf3, putative 0.0035 0.0241 0.0212
Loa Loa (eye worm) hypothetical protein 0.0035 0.0251 0.0496
Loa Loa (eye worm) hypothetical protein 0.003 0.018 0.0357
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0045 0.0378 0.0484
Echinococcus granulosus intermediate filament protein 0.0026 0.0137 0.0165
Toxoplasma gondii ABC1 family protein 0.0035 0.0251 0.115
Loa Loa (eye worm) 6-phosphofructokinase 0.0107 0.1165 0.2305
Brugia malayi Steroid receptor seven-up type 2 0.003 0.018 0.0357
Loa Loa (eye worm) hypothetical protein 0.003 0.018 0.0357
Leishmania major heat shock protein 83-1 0.0064 0.0619 0.1037
Schistosoma mansoni endoplasmin 0.0064 0.0619 0.1203
Schistosoma mansoni hypothetical protein 0.0041 0.0319 0.0621
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0986 0.1508
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0167 0.0058
Plasmodium falciparum heat shock protein 90 0.0064 0.0619 0.3818
Mycobacterium ulcerans heat shock protein 90 0.0051 0.0452 0.0437
Brugia malayi Endoplasmin precursor 0.0064 0.0619 0.1224
Plasmodium vivax glutathione reductase, putative 0.0131 0.1472 1
Trypanosoma brucei ISWI complex protein 0.003 0.0184 0.0182
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0045 0.0378 0.0454
Onchocerca volvulus 0.0035 0.0251 0.0206
Echinococcus granulosus geminin 0.0166 0.193 0.2317
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0107 0.1165 0.2046
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0298 0.3618 0.4281
Loa Loa (eye worm) hypothetical protein 0.003 0.018 0.0357
Loa Loa (eye worm) hypothetical protein 0.003 0.018 0.0357
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0167 0.0545
Brugia malayi Pre-SET motif family protein 0.0059 0.0552 0.1092
Mycobacterium tuberculosis Probable reductase 0.0298 0.3618 0.4281
Onchocerca volvulus 0.003 0.0183 0.0086
Schistosoma mansoni jumonji/arid domain-containing protein 0.0062 0.0586 0.1139
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.003 0.018 0.0217
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0059 0.0552 0.3333
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0118 0.1306 0.1569
Onchocerca volvulus 0.0035 0.0251 0.0206
Loa Loa (eye worm) hypothetical protein 0.0049 0.0425 0.0841
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0635 0.0994
Trichomonas vaginalis mercuric reductase, putative 0.0045 0.0378 0.0432
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0251 0.0496
Onchocerca volvulus 0.003 0.018 0.0081
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0241 0.0189
Brugia malayi serine/threonine-protein kinase plk-2 0.0093 0.0986 0.1951
Echinococcus multilocularis zinc finger protein 0.0039 0.0293 0.0293
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0167 0.2631
Loa Loa (eye worm) hypothetical protein 0.0092 0.0983 0.1944
Brugia malayi Nuclear hormone receptor family member nhr-3 0.003 0.018 0.0357
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0045 0.0378 0.0378
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.003 0.018 0.0357
Trypanosoma brucei polo-like protein kinase 0.0093 0.0986 0.176
Brugia malayi Pre-SET motif family protein 0.041 0.5056 1
Brugia malayi jmjC domain containing protein 0.0062 0.0586 0.1159
Entamoeba histolytica hypothetical protein 0.0035 0.0241 0.1391
Brugia malayi jmjC domain containing protein 0.0058 0.0538 0.1064
Brugia malayi beta-lactamase family protein 0.0035 0.0251 0.0496
Entamoeba histolytica phosphofructokinase, putative 0.0107 0.1165 1
Trypanosoma brucei hypothetical protein, conserved 0.0419 0.5173 1
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.012 0.1332 0.16
Echinococcus granulosus L aminoadipate semialdehyde 0.0082 0.0844 0.1013
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0298 0.3618 0.4281
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0045 0.0378 0.7952
Leishmania major heat shock protein 83-1 0.0064 0.0619 0.1037
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0251 0.0231
Loa Loa (eye worm) glutathione reductase 0.0131 0.1472 0.2912
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.1165 0.1825
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0167 0.0545
Echinococcus granulosus lysine specific demethylase 5A 0.0062 0.0586 0.0704
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0045 0.0378 0.0735
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0107 0.1165 0.2113
Trichomonas vaginalis heat shock protein, putative 0.0051 0.0452 0.0562
Toxoplasma gondii NAC domain-containing protein 0.0035 0.0241 0.1082
Brugia malayi PHD-finger family protein 0.0049 0.0427 0.0845
Mycobacterium tuberculosis Conserved protein 0.0035 0.0251 0.0193
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0029 0.0167 0.0058
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.012 0.1332 0.1506
Leishmania major heat shock protein 83-1 0.0064 0.0619 0.1037
Loa Loa (eye worm) hypothetical protein 0.0035 0.0251 0.0496
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.003 0.018 0.0217
Trichomonas vaginalis heat shock protein, putative 0.0051 0.0452 0.0562
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0167 0.0545
Echinococcus granulosus transcription factor Dp 1 0.0038 0.0283 0.0339
Loa Loa (eye worm) heat shock protein 75 0.0026 0.0134 0.0266
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.018 0.0217
Mycobacterium ulcerans beta-lactamase 0.0035 0.0251 0.0193
Schistosoma mansoni hypothetical protein 0.0166 0.193 0.3751
Trypanosoma brucei trypanothione reductase 0.0131 0.1472 0.2717
Mycobacterium ulcerans hypothetical protein 0.0048 0.0417 0.0394
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0167 0.0545
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0107 0.1165 0.1303
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0251 0.0206
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0251 0.0206
Trypanosoma cruzi hypothetical protein, conserved 0.0419 0.5173 1
Schistosoma mansoni nuclear hormone receptor 0.003 0.018 0.0351
Leishmania major heat shock protein 83-1 0.0064 0.0619 0.1037
Trypanosoma cruzi trypanothione reductase, putative 0.0045 0.0378 0.0484
Trypanosoma cruzi heat shock protein 90, putative 0.0064 0.0619 0.0962
Loa Loa (eye worm) hypothetical protein 0.0082 0.0844 0.1669
Trypanosoma cruzi heat shock protein 85, putative 0.0064 0.0619 0.0962
Loa Loa (eye worm) endoplasmin 0.0064 0.0619 0.1224
Schistosoma mansoni jumonji/arid domain-containing protein 0.0062 0.0586 0.1139
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0298 0.3618 0.4281
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0251 0.0488
Trypanosoma brucei heat shock protein, putative 0.0064 0.0619 0.1037
Toxoplasma gondii 6-phosphofructokinase 0.0029 0.0167 0.0545
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0986 0.1508
Leishmania major hypothetical protein, conserved 0.0419 0.5173 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.003 0.018 0.0357
Echinococcus multilocularis lamin dm0 0.0026 0.0137 0.0137
Entamoeba histolytica phosphofructokinase, putative 0.0107 0.1165 1
Echinococcus granulosus heat shock protein 90 0.0064 0.0619 0.0743
Plasmodium vivax heat shock protein, putative 0.0026 0.0134 0.0306
Giardia lamblia NADH oxidase lateral transfer candidate 0.0045 0.0378 0.2574
Mycobacterium tuberculosis Probable anthranilate phosphoribosyltransferase TrpD 0.0188 0.2206 0.2566
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0167 0.0058
Schistosoma mansoni bromodomain containing protein 0.0125 0.1397 0.2715
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0251 0.0193
Schistosoma mansoni aldehyde dehydrogenase 0.012 0.1332 0.2589
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0251 0.0496
Leishmania major basic transcription factor 3a, putative 0.0035 0.0241 0.0294
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.1165 0.1825
Mycobacterium tuberculosis Probable oxidoreductase 0.0331 0.4044 0.4798
Mycobacterium tuberculosis Probable dehydrogenase 0.0298 0.3618 0.4281
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0045 0.0378 0.2072
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0251 0.0313
Brugia malayi Bromodomain containing protein 0.0148 0.1693 0.3348
Toxoplasma gondii heat shock protein HSP90 0.0064 0.0619 0.3818
Loa Loa (eye worm) hypothetical protein 0.003 0.0183 0.0362
Onchocerca volvulus 0.0467 0.5783 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.0251 0.0496
Echinococcus multilocularis musashi 0.0026 0.0137 0.0137
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0026 0.0134 0.0134
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.003 0.018 0.0217
Plasmodium falciparum thioredoxin reductase 0.0131 0.1472 1
Trypanosoma cruzi ISWI complex protein 0.003 0.0184 0.0099
Echinococcus granulosus ecdysone induced protein 78C 0.003 0.018 0.0217
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0251 0.0193
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0167 0.0058
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0251 0.0193
Trypanosoma cruzi hypothetical protein, conserved 0.0419 0.5173 1
Schistosoma mansoni kinase 0.0047 0.0402 0.0781
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.018 0.0357
Loa Loa (eye worm) hypothetical protein 0.003 0.018 0.0357
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.003 0.018 0.0351
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0065 0.0635 0.0763
Loa Loa (eye worm) hypothetical protein 0.0038 0.0289 0.0572
Leishmania major heat shock protein, putative 0.0026 0.0134 0.0083
Schistosoma mansoni transcription factor btf3 0.0035 0.0241 0.0469
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.003 0.018 0.0351
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0331 0.4044 1
Schistosoma mansoni chromobox protein 0.0068 0.0674 0.1311
Leishmania major heat shock protein 83-1 0.0064 0.0619 0.1037
Brugia malayi nuclear hormone receptor 0.003 0.018 0.0357
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0986 0.1508
Trypanosoma brucei heat shock protein, putative 0.0064 0.0619 0.1037
Brugia malayi chromobox protein homolog 3 0.0038 0.0289 0.0572
Loa Loa (eye worm) hypothetical protein 0.0026 0.0131 0.0259
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0045 0.0378 0.0347
Trypanosoma brucei heat shock protein, putative 0.0064 0.0619 0.1037
Mycobacterium ulcerans hypothetical protein 0.0035 0.0251 0.0193
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0033 0.0224 0.0443
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0251 0.0193
Loa Loa (eye worm) hypothetical protein 0.0026 0.0137 0.0271
Entamoeba histolytica phosphofructokinase, putative 0.0107 0.1165 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.018 0.0357
Onchocerca volvulus Serine\/threonine kinase homolog 0.0093 0.0986 0.1508
Onchocerca volvulus 0.007 0.0696 0.0994
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0986 0.1508
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0093 0.0986 0.176
Loa Loa (eye worm) phosphofructokinase 0.0107 0.1165 0.2305
Leishmania major heat shock protein 83-1 0.0064 0.0619 0.1037
Trypanosoma brucei heat shock protein, putative 0.0064 0.0619 0.1037
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.003 0.018 0.018
Treponema pallidum heat shock protein 90 0.0051 0.0452 0.3352
Echinococcus multilocularis lamin 0.0026 0.0137 0.0137
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0045 0.0378 0.0563
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0045 0.0378 0.2072
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0167 0.0058
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0137 0.0271
Echinococcus multilocularis transcription factor btf3 0.0035 0.0241 0.0241
Loa Loa (eye worm) ICD-1 protein 0.0035 0.0241 0.0477
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0045 0.0378 0.2072
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0065 0.0635 0.0635
Loa Loa (eye worm) hypothetical protein 0.0076 0.0767 0.1518
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.003 0.018 0.018
Brugia malayi intermediate filament protein 0.0026 0.0137 0.0271
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0045 0.0378 0.0484
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0045 0.0378 0.2072
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0093 0.0986 0.0986
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0327 0.034
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0048 0.0417 0.0394
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0048 0.0417 0.0394
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.018 0.0357
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0065 0.0635 0.1069
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.018 0.018
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.0227 0.0448
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0065 0.0635 0.506
Echinococcus granulosus retinoic acid receptor rxr beta a 0.003 0.018 0.0217
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0986 0.1508
Echinococcus granulosus chromobox protein 1 0.0068 0.0674 0.081
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0045 0.0378 0.0484
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0386 0.0446
Trypanosoma brucei heat shock protein, putative 0.0064 0.0619 0.1037
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0029 0.0167 0.0701
Plasmodium falciparum glutathione reductase 0.0045 0.0378 0.2072
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0045 0.0378 0.0484
Toxoplasma gondii thioredoxin reductase 0.0131 0.1472 1
Loa Loa (eye worm) hypothetical protein 0.003 0.018 0.0357
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0026 0.0134 0.0161
Brugia malayi beta-lactamase family protein 0.0035 0.0251 0.0496
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.003 0.018 0.018
Schistosoma mansoni lamin 0.0026 0.0137 0.0267
Schistosoma mansoni lamin 0.0026 0.0137 0.0267
Schistosoma mansoni RAR-like nuclear receptor 0.003 0.018 0.0351
Trypanosoma cruzi trypanothione reductase, putative 0.0131 0.1472 0.2656
Loa Loa (eye worm) heterochromatin protein 1 0.0068 0.0674 0.1334
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0045 0.0378 0.0563
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0298 0.3618 0.8921
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0118 0.1306 0.1306
Trypanosoma cruzi Heat shock protein 83, putative 0.0064 0.0619 0.0962
Brugia malayi Nuclear hormone receptor family member nhr-49 0.003 0.018 0.0357
Plasmodium falciparum heat shock protein 90, putative 0.0026 0.0134 0.0306
Schistosoma mansoni aldehyde dehydrogenase 0.012 0.1332 0.2589
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0051 0.0452 1
Schistosoma mansoni hypothetical protein 0.003 0.0184 0.0359
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0327 0.034
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.003 0.018 0.0217
Mycobacterium leprae conserved hypothetical protein 0.0035 0.0251 0.0402
Brugia malayi phosphofructokinase 0.0107 0.1165 0.2305
Onchocerca volvulus Bile acid receptor homolog 0.003 0.018 0.0081
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0251 0.0206
Schistosoma mansoni serine/threonine protein kinase 0.0093 0.0986 0.1917
Plasmodium falciparum endoplasmin, putative 0.0039 0.0302 0.1518
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0107 0.1165 0.2716
Leishmania major ATP-dependent phosphofructokinase 0.0107 0.1165 0.2113
Toxoplasma gondii NADPH-glutathione reductase 0.0045 0.0378 0.2072
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.003 0.018 0.0357
Echinococcus granulosus citrate lyase subunit beta protein 0.0048 0.0417 0.0501
Onchocerca volvulus 0.0148 0.1699 0.277
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0048 0.0417 0.0639
Trichomonas vaginalis endoplasmin, putative 0.0039 0.0302 0.0296
Leishmania major hypothetical protein, conserved 0.003 0.0184 0.0182
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0033 0.0224 0.0443
Loa Loa (eye worm) heat shock protein 90 0.0064 0.0619 0.1224
Echinococcus granulosus heat shock protein 0.0064 0.0619 0.0743
Loa Loa (eye worm) hypothetical protein 0.008 0.0827 0.1636
Echinococcus multilocularis heat shock protein 90 0.0064 0.0619 0.0619
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0071 0.0706 0.0848
Schistosoma mansoni intermediate filament proteins 0.0026 0.0137 0.0267
Trypanosoma brucei heat shock protein 90, putative 0.0064 0.0619 0.1037
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.041 0.5056 1
Plasmodium falciparum thioredoxin reductase 0.0045 0.0378 0.2072
Leishmania major heat shock protein 83-1 0.0064 0.0619 0.1037
Trichomonas vaginalis heat shock protein, putative 0.0039 0.0302 0.0296
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0065 0.0635 0.1256
Trypanosoma brucei heat shock protein 90, putative 0.0064 0.0619 0.1037
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0986 0.1508
Plasmodium vivax thioredoxin reductase, putative 0.0131 0.1472 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0045 0.0378 0.0484
Brugia malayi photoreceptor-specific nuclear receptor 0.003 0.018 0.0357
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0045 0.0378 0.0563
Trichomonas vaginalis glutathione reductase, putative 0.0045 0.0378 0.0432
Schistosoma mansoni heat shock protein 0.0064 0.0619 0.1203
Toxoplasma gondii phosphofructokinase PFKII 0.0029 0.0167 0.0545
Schistosoma mansoni steroid hormone receptor ad4bp 0.003 0.018 0.0351
Mycobacterium ulcerans thymidine phosphorylase 0.0666 0.8327 1
Echinococcus granulosus transcription factor btf3 0.0035 0.0241 0.029
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.012 0.1332 0.244
Giardia lamblia Heat shock protein HSP 90-alpha 0.0051 0.0452 0.3474
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0986 0.1508
Echinococcus granulosus thymidine phosphorylase 0.0666 0.8327 1
Trypanosoma brucei heat shock protein, putative 0.0064 0.0619 0.1037
Echinococcus multilocularis heat shock protein 0.0064 0.0619 0.0619
Trichomonas vaginalis heat shock protein, putative 0.0051 0.0452 0.0562
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.018 0.0217
Schistosoma mansoni coup transcription factor 0.003 0.018 0.0351
Plasmodium vivax heat shock protein 86, putative 0.0064 0.0619 0.3818
Plasmodium vivax basic transcription factor 3b, putative 0.0035 0.0241 0.1082
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0251 0.0206
Echinococcus granulosus methyl CpG binding domain protein 2 0.0034 0.0229 0.0275
Echinococcus granulosus 6 phosphofructokinase 0.0107 0.1165 0.14
Toxoplasma gondii heat shock protein 75, putative 0.0026 0.0134 0.0306
Brugia malayi Heterochromatin protein 1 0.0068 0.0674 0.1334
Plasmodium falciparum glutathione reductase 0.0131 0.1472 1
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0044 0.0367 0.0367
Brugia malayi Nuclear hormone receptor family member nhr-31 0.003 0.018 0.0357
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0093 0.0986 0.1184
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.003 0.018 0.0351
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0092 0.0983 0.1911
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0327 0.034
Loa Loa (eye worm) bromodomain containing protein 0.0035 0.0244 0.0483
Schistosoma mansoni methyl-cpg binding protein mbd 0.0034 0.0229 0.0445
Echinococcus multilocularis ecdysone induced protein 78C 0.003 0.018 0.018
Brugia malayi beta-NAC-like protein 0.0035 0.0241 0.0477
Schistosoma mansoni retinoid-x-receptor (RXR) 0.003 0.018 0.0351
Echinococcus multilocularis lysine specific demethylase 5A 0.0058 0.0538 0.0538
Echinococcus granulosus lamin dm0 0.0026 0.0137 0.0165
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0674 0.0956
Trypanosoma cruzi heat shock protein 90, putative 0.0038 0.0283 0.0294
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0298 0.3618 0.4281
Schistosoma mansoni methyl-cpg binding protein mbd 0.0034 0.0229 0.0445
Plasmodium vivax SET domain protein, putative 0.0059 0.0552 0.3333
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0045 0.0378 0.2072
Leishmania major heat shock protein 83-1 0.0064 0.0619 0.1037
Trypanosoma cruzi heat shock protein 90, putative 0.0051 0.0452 0.063
Giardia lamblia Kinase, PLK 0.0093 0.0986 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.003 0.018 0.0357
Echinococcus granulosus histone lysine methyltransferase setb 0.0092 0.0983 0.118
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.018 0.0357
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0635 0.1069
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0082 0.0844 0.1641
Echinococcus multilocularis L aminoadipate semialdehyde 0.0082 0.0844 0.0844
Schistosoma mansoni hypothetical protein 0.0033 0.0227 0.0441
Plasmodium vivax heat shock protein 90, putative 0.0026 0.0134 0.0306
Trypanosoma brucei heat shock protein, putative 0.0064 0.0619 0.1037
Leishmania major heat shock protein 83-1 0.0064 0.0619 0.1037
Loa Loa (eye worm) 6-phosphofructokinase 0.0107 0.1165 0.2305
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0045 0.0378 0.0563
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0635 0.0994
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0425 0.0841
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0045 0.0378 0.0484
Mycobacterium tuberculosis Conserved protein 0.0035 0.0251 0.0193
Echinococcus granulosus endoplasmin 0.0051 0.0452 0.0543
Trichomonas vaginalis set domain proteins, putative 0.0467 0.5783 1
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0167 0.0058
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0331 0.4044 0.4798
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0029 0.0167 0.0545
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0071 0.0706 0.0706
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0251 0.0193
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.007 0.0696 0.1352
Schistosoma mansoni Tr4/Tr2 (homologue) 0.003 0.018 0.0351
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0251 0.0251
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0226 0.2692 0.3157
Mycobacterium ulcerans lipase LipD 0.0035 0.0251 0.0193
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0051 0.0452 0.0437
Brugia malayi Nuclear hormone receptor family member nhr-14 0.003 0.018 0.0357
Trypanosoma cruzi heat shock protein 85, putative 0.0064 0.0619 0.0962
Entamoeba histolytica heat shock protein 90, putative 0.0064 0.0619 0.491
Leishmania major trypanothione reductase 0.0131 0.1472 0.2717
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0051 0.0452 0.091
Leishmania major heat shock protein 83-1 0.0064 0.0619 0.1037
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0251 0.0193
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0251 0.0193
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0051 0.0452 0.0543
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.1165 0.1825
Schistosoma mansoni endoplasmin 0.0064 0.0619 0.1203
Brugia malayi nuclear receptor NHR-88 0.003 0.018 0.0357
Mycobacterium ulcerans anthranilate phosphoribosyltransferase 0.0188 0.2206 0.2566
Onchocerca volvulus 0.0035 0.0251 0.0206
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0386 0.0446
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0045 0.0378 1
Onchocerca volvulus 0.0082 0.0844 0.1256
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.003 0.018 0.0081
Loa Loa (eye worm) hypothetical protein 0.003 0.018 0.0357
Leishmania major heat shock protein 83-1 0.0064 0.0619 0.1037
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0026 0.0134 0.0394
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0045 0.0378 0.0563
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0029 0.0167 0.0701
Echinococcus multilocularis chromobox protein 1 0.0068 0.0674 0.0674
Giardia lamblia Grp94/Hsp90 0.0051 0.0452 0.3474
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0146 0.002
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0251 0.115
Schistosoma mansoni 6-phosphofructokinase 0.0107 0.1165 0.2265
Loa Loa (eye worm) thioredoxin reductase 0.0131 0.1472 0.2912
Toxoplasma gondii aldehyde dehydrogenase 0.012 0.1332 0.8983
Loa Loa (eye worm) hypothetical protein 0.0035 0.0251 0.0496
Brugia malayi Thioredoxin reductase 0.0131 0.1472 0.2912
Loa Loa (eye worm) jmjC domain-containing protein 0.0062 0.0586 0.1159
Brugia malayi ecdysteroid receptor 0.003 0.018 0.0357
Schistosoma mansoni hypothetical protein 0.0166 0.193 0.3751
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.003 0.018 0.0357
Schistosoma mansoni zinc finger protein 0.0039 0.0293 0.0569
Echinococcus multilocularis endoplasmin 0.0051 0.0452 0.0452
Leishmania major heat shock protein 83-1 0.0064 0.0619 0.1037
Echinococcus multilocularis heat shock protein 90 0.0051 0.0452 0.0452
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0045 0.0378 0.0347
Trypanosoma cruzi polo-like protein kinase, putative 0.0093 0.0986 0.1691
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0019 0.0044 0.0044
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0137 0.0271
Loa Loa (eye worm) hypothetical protein 0.0033 0.0227 0.0448
Giardia lamblia Heat shock protein HSP 90-alpha 0.0064 0.0619 0.5516
Brugia malayi steroid hormone receptor 0.003 0.018 0.0357
Echinococcus granulosus FTZ F1 alpha 0.003 0.018 0.0217
Echinococcus multilocularis transcription factor Dp 1 0.0038 0.0283 0.0283
Echinococcus multilocularis geminin 0.0166 0.193 0.193
Mycobacterium ulcerans aldehyde dehydrogenase 0.012 0.1332 0.1506
Brugia malayi 6-phosphofructokinase 0.0107 0.1165 0.2305
Trypanosoma cruzi heat shock protein 85, putative 0.0051 0.0452 0.063
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0048 0.0417 0.0561
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0057 0.0524 0.063
Entamoeba histolytica transcription factor BTF3, putative 0.0035 0.0241 0.1391
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0059 0.0552 0.0552
Brugia malayi Nuclear hormone receptor-like 1 0.003 0.018 0.0357
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0045 0.0378 0.0563
Plasmodium falciparum basic transcription factor 3b, putative 0.0035 0.0241 0.1082
Loa Loa (eye worm) PHD-finger family protein 0.0041 0.0319 0.0631
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0167 0.0058
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0048 0.0417 0.0394
Loa Loa (eye worm) beta-lactamase 0.0035 0.0251 0.0496
Schistosoma mansoni retinoic acid receptor RXR 0.003 0.018 0.0351
Schistosoma mansoni heat shock protein 0.0026 0.0134 0.0261
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.1165 0.1825
Echinococcus multilocularis FTZ F1 alpha 0.003 0.018 0.018
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0092 0.0983 0.0983
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0251 0.0193
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0093 0.0986 0.1951
Mycobacterium tuberculosis Conserved protein 0.0048 0.0417 0.0394
Treponema pallidum NADH oxidase 0.0045 0.0378 0.2665
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0251 0.0301
Toxoplasma gondii heat shock protein 90, putative 0.0064 0.0619 0.3818
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0092 0.0983 0.1911
Echinococcus multilocularis 6 phosphofructokinase 0.0107 0.1165 0.1165
Entamoeba histolytica serine/threonine protein kinase, putative 0.0093 0.0986 0.8331
Brugia malayi Nuclear hormone receptor family member nhr-40 0.003 0.018 0.0357
Mycobacterium tuberculosis Probable thymidine phosphorylase DeoA (tdrpase) (pyrimidine phosphorylase) 0.0666 0.8327 1
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0107 0.1165 1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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