Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium tuberculosis | Probable polyketide synthase Pks17 | 0.0075 | 0.0708 | 0.1014 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsB | 0.0047 | 0.0353 | 0.0371 |
Mycobacterium ulcerans | hypothetical protein | 0.0072 | 0.0679 | 0.1222 |
Toxoplasma gondii | 3-oxoacyl-acyl-carrier protein synthase I/II, putative | 0.0077 | 0.0734 | 0.1897 |
Toxoplasma gondii | type I fatty acid synthase, putative | 0.0321 | 0.3869 | 1 |
Mycobacterium tuberculosis | Probable polyketide beta-ketoacyl synthase Pks4 | 0.0047 | 0.0353 | 0.0371 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.019 | 0.0224 |
Loa Loa (eye worm) | hypothetical protein | 0.0121 | 0.1301 | 0.2072 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0142 | 0.0167 |
Echinococcus multilocularis | Acyl carrier protein, mitochondrial | 0.0031 | 0.0148 | 0.0148 |
Plasmodium vivax | acyl carrier protein, putative | 0.0031 | 0.0148 | 0.2016 |
Mycobacterium ulcerans | polyketide synthase Pks13 | 0.0453 | 0.5558 | 1 |
Leishmania major | acyl carrier protein, putative | 0.0031 | 0.0148 | 0.1591 |
Onchocerca volvulus | 0.0072 | 0.0679 | 0.0837 | |
Mycobacterium ulcerans | polyketide synthase Pks9 | 0.0199 | 0.2303 | 0.4143 |
Toxoplasma gondii | ABC1 family protein | 0.0072 | 0.0679 | 0.1755 |
Echinococcus multilocularis | 3 oxoacyl (acyl carrier protein) synthase | 0.0077 | 0.0734 | 0.0734 |
Trypanosoma cruzi | beta-ketoacyl synthase family protein, putative | 0.0077 | 0.0734 | 1 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase | 0.0031 | 0.0148 | 0.0266 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0057 | 0.0488 | 0.0685 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0028 | 0.0115 | 0.0135 |
Loa Loa (eye worm) | beta-lactamase | 0.0072 | 0.0679 | 0.1081 |
Echinococcus multilocularis | cpg binding protein | 0.003 | 0.0142 | 0.0142 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0224 | 1 |
Brugia malayi | Beta-ketoacyl synthase, N-terminal domain containing protein | 0.0302 | 0.3626 | 0.509 |
Brugia malayi | beta-lactamase family protein | 0.0072 | 0.0679 | 0.0953 |
Giardia lamblia | Methyltransferase like 2 | 0.0092 | 0.093 | 0.5 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0037 | 0.0224 | 0.0264 |
Mycobacterium ulcerans | 3-oxoacyl-(acyl carrier protein) synthase II | 0.0077 | 0.0734 | 0.132 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.006 | 0.0521 | 0.0675 |
Onchocerca volvulus | Fatty acid synthase homolog | 0.055 | 0.6796 | 1 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.006 | 0.0521 | 0.1346 |
Mycobacterium tuberculosis | Probable thioesterase TesA | 0.0254 | 0.3009 | 0.5183 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0093 | 0.0945 | 0.1115 |
Mycobacterium ulcerans | phenyloxazoline synthase MbtB | 0.0031 | 0.0148 | 0.0266 |
Mycobacterium ulcerans | hypothetical protein | 0.0031 | 0.0148 | 0.0266 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0072 | 0.0679 | 0.9253 |
Toxoplasma gondii | beta-ketoacyl synthase, N-terminal domain-containing protein | 0.0198 | 0.2288 | 0.5913 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0093 | 0.0945 | 0.0945 |
Schistosoma mansoni | hypothetical protein | 0.0341 | 0.4123 | 0.4866 |
Mycobacterium tuberculosis | Polyketide synthase Pks13 | 0.0453 | 0.5558 | 0.9802 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.0121 | 0.0142 |
Leishmania major | beta-ketoacyl synthase family protein, putative,3-oxoacyl-acyl carrier protein synthase ii, putative | 0.0077 | 0.0734 | 0.789 |
Brugia malayi | Pre-SET motif family protein | 0.0205 | 0.2375 | 0.3334 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.0521 | 0.0937 |
Brugia malayi | Methyltransferase-like protein 4 | 0.0092 | 0.093 | 0.1306 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0076 | 0.0726 | 0.9888 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0681 | 0.8473 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0092 | 0.093 | 0.1221 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0224 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0679 | 0.1081 |
Mycobacterium ulcerans | polyketide synthase | 0.0321 | 0.3869 | 0.6961 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.006 | 0.0521 | 0.0614 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0681 | 0.8473 | 1 |
Loa Loa (eye worm) | beta-ketoacyl synthase domain-containing protein | 0.0077 | 0.0734 | 0.1168 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0093 | 0.0945 | 0.1326 |
Leishmania major | hypothetical protein, conserved | 0.0092 | 0.093 | 1 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0034 | 0.019 | 0.0224 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0679 | 0.1081 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0148 | 0.0175 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0072 | 0.0679 | 0.0962 |
Echinococcus granulosus | NADH dehydrogenase | 0.0031 | 0.0148 | 0.0175 |
Echinococcus multilocularis | AMP dependent ligase | 0.0031 | 0.0148 | 0.0148 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0224 | 1 |
Brugia malayi | hypothetical protein | 0.0037 | 0.0224 | 0.0314 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0072 | 0.0679 | 0.9253 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC | 0.0321 | 0.3869 | 0.6877 |
Mycobacterium leprae | Polyketide synthase Pks13 | 0.0453 | 0.5558 | 1 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0037 | 0.0224 | 0.0224 |
Toxoplasma gondii | AMP-binding enzyme domain-containing protein | 0.0154 | 0.1728 | 0.4466 |
Mycobacterium tuberculosis | Conserved protein | 0.0072 | 0.0679 | 0.0962 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0302 | 0.3626 | 0.6524 |
Mycobacterium tuberculosis | Probable membrane bound polyketide synthase Pks6 | 0.0453 | 0.5558 | 0.9802 |
Onchocerca volvulus | 0.0072 | 0.0679 | 0.0837 | |
Toxoplasma gondii | type I fatty acid synthase | 0.0047 | 0.0353 | 0.0911 |
Mycobacterium leprae | Probable lipase LipE | 0.0072 | 0.0679 | 0.0982 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0256 | 0.0407 |
Onchocerca volvulus | Huntingtin homolog | 0.0121 | 0.1301 | 0.1769 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0072 | 0.0679 | 0.0962 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks8 | 0.0247 | 0.2914 | 0.5012 |
Mycobacterium tuberculosis | Probable polyketide beta-ketoacyl synthase Pks3 | 0.0047 | 0.0353 | 0.0371 |
Loa Loa (eye worm) | phosphopantetheine attachment site family protein | 0.0031 | 0.0148 | 0.0236 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0072 | 0.0679 | 0.0679 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0057 | 0.0488 | 0.0685 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0119 | 0.128 | 0.2037 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0072 | 0.0679 | 0.0962 |
Brugia malayi | oxidoreductase, zinc-binding dehydrogenase family protein | 0.0576 | 0.7124 | 1 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0076 | 0.0726 | 0.9888 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsD | 0.0302 | 0.3626 | 0.6524 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0039 | 0.0256 | 0.0359 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0072 | 0.0679 | 0.0962 |
Onchocerca volvulus | 0.003 | 0.0136 | 0.0024 | |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.003 | 0.0136 | 0.0161 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0076 | 0.0726 | 0.9888 |
Plasmodium falciparum | 3-oxoacyl-acyl-carrier protein synthase I/II | 0.0077 | 0.0734 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0093 | 0.0945 | 0.1115 |
Onchocerca volvulus | 0.0285 | 0.3403 | 0.4918 | |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0076 | 0.0726 | 0.9888 |
Mycobacterium ulcerans | thioesterase | 0.0254 | 0.3009 | 0.5413 |
Onchocerca volvulus | 0.0233 | 0.2736 | 0.3919 | |
Mycobacterium leprae | Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas | 0.0321 | 0.3869 | 0.6877 |
Mycobacterium ulcerans | polyketide synthase MbtC | 0.0077 | 0.0734 | 0.132 |
Brugia malayi | beta-lactamase | 0.0072 | 0.0679 | 0.0953 |
Trypanosoma brucei | beta-ketoacyl-ACP synthase | 0.0077 | 0.0734 | 1 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase MbtE | 0.0031 | 0.0148 | 0.0266 |
Wolbachia endosymbiont of Brugia malayi | acyl carrier protein | 0.0031 | 0.0148 | 0.2016 |
Mycobacterium tuberculosis | Hypothetical protein | 0.0092 | 0.093 | 0.1417 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0072 | 0.0679 | 0.0802 |
Treponema pallidum | acyl carrier protein | 0.0031 | 0.0148 | 0.5 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.0285 | 0.3403 | 0.5898 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.0488 | 0.0777 |
Mycobacterium ulcerans | acyl carrier protein | 0.0031 | 0.0148 | 0.0266 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0031 | 0.0148 | 0.0208 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0093 | 0.0945 | 0.1115 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB | 0.0243 | 0.2863 | 0.5018 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks5 | 0.0296 | 0.354 | 0.6146 |
Brugia malayi | beta-lactamase family protein | 0.0072 | 0.0679 | 0.0953 |
Brugia malayi | hypothetical protein | 0.0121 | 0.1301 | 0.1827 |
Brugia malayi | hypothetical protein | 0.0076 | 0.0726 | 0.1019 |
Mycobacterium leprae | conserved hypothetical protein | 0.0072 | 0.0679 | 0.0982 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD | 0.0302 | 0.3626 | 0.6429 |
Echinococcus granulosus | cpg binding protein | 0.003 | 0.0142 | 0.0167 |
Mycobacterium ulcerans | multifunctional mycocerosic acid synthase membrane-associated Mas | 0.0321 | 0.3869 | 0.6961 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.003 | 0.0136 | 0.0136 |
Mycobacterium ulcerans | fatty acid synthase Fas | 0.0096 | 0.0981 | 0.1764 |
Onchocerca volvulus | 0.0072 | 0.0679 | 0.0837 | |
Chlamydia trachomatis | 3-oxoacyl-ACP synthase | 0.0077 | 0.0734 | 1 |
Mycobacterium tuberculosis | Polyketide synthase Pks12 | 0.0321 | 0.3869 | 0.6741 |
Mycobacterium tuberculosis | Conserved protein | 0.0072 | 0.0679 | 0.0962 |
Mycobacterium tuberculosis | Conserved protein | 0.0072 | 0.0679 | 0.0962 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0142 | 0.0167 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0726 | 0.1155 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsE | 0.0047 | 0.0353 | 0.0371 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks15 | 0.0123 | 0.1333 | 0.2147 |
Mycobacterium ulcerans | thioesterase TesA | 0.0254 | 0.3009 | 0.5413 |
Schistosoma mansoni | methyltransferase-related | 0.0092 | 0.093 | 0.1098 |
Loa Loa (eye worm) | hypothetical protein | 0.0121 | 0.1301 | 0.2072 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsC | 0.0302 | 0.3626 | 0.6301 |
Plasmodium vivax | SET domain protein, putative | 0.003 | 0.0136 | 0.1858 |
Plasmodium falciparum | conserved Plasmodium protein, unknown function | 0.0044 | 0.0313 | 0.4269 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0072 | 0.0679 | 0.1222 |
Mycobacterium tuberculosis | Polyketide synthetase MbtC (polyketide synthase) | 0.0102 | 0.1063 | 0.1657 |
Mycobacterium tuberculosis | Probable multifunctional mycocerosic acid synthase membrane-associated Mas | 0.0321 | 0.3869 | 0.6741 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0057 | 0.0488 | 0.0777 |
Mycobacterium tuberculosis | Polyketide synthetase MbtD (polyketide synthase) | 0.0094 | 0.0955 | 0.1461 |
Mycobacterium tuberculosis | Probable fatty acid synthase Fas (fatty acid synthetase) | 0.0096 | 0.0981 | 0.1508 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0679 | 0.1081 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0072 | 0.0679 | 0.0802 |
Mycobacterium leprae | PROBABLE FATTY ACID SYNTHASE FAS (FATTY ACID SYNTHETASE) | 0.0096 | 0.0981 | 0.1539 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0302 | 0.3626 | 0.6524 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsE | 0.0199 | 0.2303 | 0.4143 |
Mycobacterium ulcerans | peptide synthetase Nrp (peptide synthase) | 0.0031 | 0.0148 | 0.0266 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.006 | 0.0521 | 0.0614 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.003 | 0.0136 | 0.0136 |
Mycobacterium ulcerans | fatty-acid-CoA ligase FadD9 | 0.0031 | 0.0148 | 0.0266 |
Trypanosoma brucei | Acyl carrier protein, mitochondrial | 0.0031 | 0.0148 | 0.2016 |
Onchocerca volvulus | 0.0031 | 0.0148 | 0.0041 | |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0076 | 0.0726 | 0.1876 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0076 | 0.0726 | 0.9888 |
Echinococcus multilocularis | geminin | 0.0341 | 0.4123 | 0.4123 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsB | 0.0243 | 0.2863 | 0.5151 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0353 | 0.0561 |
Loa Loa (eye worm) | acyl carrier protein | 0.0031 | 0.0148 | 0.0236 |
Mycobacterium ulcerans | beta-lactamase | 0.0072 | 0.0679 | 0.1222 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0093 | 0.0945 | 0.0945 |
Loa Loa (eye worm) | fatty acid synthase | 0.0301 | 0.3608 | 0.5743 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsC | 0.0321 | 0.3869 | 0.6961 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0679 | 0.1081 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.0256 | 0.0302 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0037 | 0.0224 | 0.0264 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0072 | 0.0679 | 0.1222 |
Echinococcus granulosus | acyl carrier protein mitochondrial | 0.0031 | 0.0148 | 0.0175 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0681 | 0.8473 | 0.8473 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0136 | 0.0161 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0076 | 0.0726 | 0.9888 |
Mycobacterium ulcerans | acyl carrier protein | 0.0031 | 0.0148 | 0.0266 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks1 | 0.0219 | 0.256 | 0.4369 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase MbtF | 0.0031 | 0.0148 | 0.0266 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0072 | 0.0679 | 0.0962 |
Mycobacterium ulcerans | lipase LipD | 0.0072 | 0.0679 | 0.1222 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0093 | 0.0945 | 0.1504 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE | 0.0199 | 0.2303 | 0.3983 |
Plasmodium vivax | hypothetical protein, conserved | 0.0044 | 0.0313 | 0.4269 |
Brugia malayi | Pre-SET motif family protein | 0.003 | 0.0136 | 0.0191 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.0521 | 0.0937 |
Plasmodium vivax | hypothetical protein, conserved | 0.0072 | 0.0679 | 0.9253 |
Echinococcus multilocularis | NADH dehydrogenase | 0.0031 | 0.0148 | 0.0148 |
Mycobacterium leprae | Probable polyketide synthase Pks1 | 0.0321 | 0.3869 | 0.6877 |
Schistosoma mansoni | 3-oxoacyl-[ACP] synthase | 0.0077 | 0.0734 | 0.0866 |
Onchocerca volvulus | Acyl carrier protein, mitochondrial homolog | 0.0031 | 0.0148 | 0.0041 |
Toxoplasma gondii | type I fatty acid synthase, putative | 0.0217 | 0.2534 | 0.655 |
Toxoplasma gondii | acyl carrier protein ACP | 0.0031 | 0.0148 | 0.0383 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0062 | 0.0546 | 0.0644 |
Mycobacterium ulcerans | polyketide synthase | 0.0302 | 0.3626 | 0.6524 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0285 | 0.3403 | 0.5417 |
Leishmania major | hypothetical protein, conserved | 0.0072 | 0.0679 | 0.7301 |
Mycobacterium leprae | PROBABLE POLYKETIDE BETA-KETOACYL SYNTHASE PKS4 | 0.0047 | 0.0353 | 0.0378 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0224 | 1 |
Plasmodium vivax | 3-oxoacyl-[acyl-carrier-protein] synthase i/ii, putative | 0.0077 | 0.0734 | 1 |
Trypanosoma cruzi | Acyl carrier protein, mitochondrial, putative | 0.0031 | 0.0148 | 0.2016 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0205 | 0.2375 | 0.3781 |
Echinococcus granulosus | 3 oxoacyl acyl carrier protein synthase | 0.0077 | 0.0734 | 0.0866 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0072 | 0.0679 | 0.0802 |
Mycobacterium leprae | PROBABLE THIOESTERASE TESA | 0.0254 | 0.3009 | 0.5288 |
Plasmodium falciparum | acyl carrier protein | 0.0031 | 0.0148 | 0.2016 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0072 | 0.0679 | 0.1081 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0353 | 0.0561 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0462 | 0.5668 | 1 |
Brugia malayi | MH2 domain containing protein | 0.0119 | 0.128 | 0.1796 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks7 | 0.0321 | 0.3869 | 0.6741 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0119 | 0.128 | 0.2037 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.006 | 0.0521 | 0.0521 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsA | 0.0302 | 0.3626 | 0.6301 |
Onchocerca volvulus | Huntingtin homolog | 0.0121 | 0.1301 | 0.1769 |
Brugia malayi | hypothetical protein | 0.0049 | 0.0381 | 0.0535 |
Brugia malayi | acyl carrier protein, mitochondrial precursor, putative | 0.0031 | 0.0148 | 0.0208 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0072 | 0.0679 | 0.0962 |
Brugia malayi | Beta-ketoacyl synthase, N-terminal domain containing protein | 0.0077 | 0.0734 | 0.103 |
Brugia malayi | CXXC zinc finger family protein | 0.0029 | 0.0121 | 0.0169 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsA | 0.0243 | 0.2863 | 0.5151 |
Schistosoma mansoni | hypothetical protein | 0.0341 | 0.4123 | 0.4866 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA | 0.0302 | 0.3626 | 0.6429 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0679 | 0.1081 |
Brugia malayi | AMP-binding enzyme family protein | 0.0094 | 0.0955 | 0.134 |
Loa Loa (eye worm) | acyl carrier protein | 0.014 | 0.155 | 0.2467 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0029 | 0.0121 | 0.0192 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0093 | 0.0945 | 0.1115 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0679 | 0.1081 |
Schistosoma mansoni | acyl carrier protein | 0.0031 | 0.0148 | 0.0175 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks9 | 0.0173 | 0.1974 | 0.3309 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.0521 | 0.0937 |
Trypanosoma cruzi | beta-ketoacyl synthase family protein, putative | 0.0077 | 0.0734 | 1 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0055 | 0.0463 | 0.1196 |
Wolbachia endosymbiont of Brugia malayi | 3-oxoacyl-ACP synthase | 0.0077 | 0.0734 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0136 | 0.0161 |
Brugia malayi | AMP-binding enzyme family protein | 0.0285 | 0.3403 | 0.4777 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0072 | 0.0679 | 0.9253 |
Mycobacterium tuberculosis | Conserved protein | 0.0092 | 0.093 | 0.1417 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.0224 | 0.0264 |
Leishmania major | hypothetical protein, conserved | 0.0076 | 0.0726 | 0.7801 |
Mycobacterium tuberculosis | Polyketide synthase Pks2 | 0.0296 | 0.354 | 0.6146 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0034 | 0.019 | 0.019 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.003 | 0.0136 | 0.0161 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0072 | 0.0679 | 0.0962 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0136 | 0.0161 |
Onchocerca volvulus | 0.0531 | 0.6553 | 0.9636 | |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0072 | 0.0679 | 0.0953 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0031 | 0.0148 | 0.0266 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0136 | 0.0217 |
Echinococcus granulosus | AMP dependent ligase | 0.0031 | 0.0148 | 0.0175 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0093 | 0.0945 | 0.1115 |
Loa Loa (eye worm) | hypothetical protein | 0.051 | 0.6282 | 1 |
Brugia malayi | Phosphopantetheine attachment site family protein | 0.0031 | 0.0148 | 0.0208 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0302 | 0.3626 | 0.6524 |
Loa Loa (eye worm) | hypothetical protein | 0.0168 | 0.1908 | 0.3038 |
Mycobacterium ulcerans | 3-oxoacyl-(acyl carrier protein) synthase II | 0.0077 | 0.0734 | 0.132 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.006 | 0.0521 | 0.5597 |
Trichomonas vaginalis | set domain proteins, putative | 0.0233 | 0.2736 | 1 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.003 | 0.0136 | 0.0352 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.006 | 0.0521 | 0.0614 |
Mycobacterium ulcerans | polyketide synthase MbtD | 0.0094 | 0.0955 | 0.1717 |
Chlamydia trachomatis | acyl carrier protein | 0.0031 | 0.0148 | 0.2016 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsD | 0.0302 | 0.3626 | 0.6301 |
Echinococcus granulosus | geminin | 0.0341 | 0.4123 | 0.4866 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.