Detailed information for compound 1601946

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 548.013 | Formula: C27H22ClN5O4S
  • H donors: 3 H acceptors: 5 LogP: 3.83 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 2
  • SMILES: Cc1ccc(cc1)S(=O)(=O)NC(=O)c1n(Cc2ccnc(c2)N)c2c(c1c1ccc[nH]c1=O)cc(cc2)Cl
  • InChi: 1S/C27H22ClN5O4S/c1-16-4-7-19(8-5-16)38(36,37)32-27(35)25-24(20-3-2-11-31-26(20)34)21-14-18(28)6-9-22(21)33(25)15-17-10-12-30-23(29)13-17/h2-14H,15H2,1H3,(H2,29,30)(H,31,34)(H,32,35)
  • InChiKey: TYQXQLWAMKVDSA-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium ulcerans aldehyde dehydrogenase 0.0058 0.0336 0.3149
Schistosoma mansoni smad 0.0013 0.0004 0.0017
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0059 0.0349 0.0349
Onchocerca volvulus Glucosylceramidase homolog 0.0153 0.1051 0.6803
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0059 0.0347 0.0347
Echinococcus granulosus potassium voltage gated channel protein 0.0059 0.0347 0.0516
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0062 0.037 0.1474
Onchocerca volvulus 0.0125 0.0844 0.5312
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0026 0.0103 0.0153
Plasmodium vivax glutathione reductase, putative 0.0076 0.0474 0.5621
Brugia malayi glutathione reductase 0.0076 0.0474 0.1889
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0059 0.0347 0.0347
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0173 0.1202 0.2039
Brugia malayi beta-lactamase family protein 0.0125 0.0844 0.3362
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0062 0.037 0.1474
Echinococcus multilocularis short transient receptor potential channel 6 0.0059 0.0347 0.0347
Brugia malayi hypothetical protein 0.0013 0.0001 0.0003
Schistosoma mansoni hypothetical protein 0.0245 0.1739 0.6929
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0026 0.0103 0.0103
Echinococcus multilocularis mothers against decapentaplegic 5 0.0013 0.0004 0.0004
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0159 0.1094 0.1094
Trichomonas vaginalis glucosylceramidase, putative 0.0153 0.1051 0.6124
Loa Loa (eye worm) hypothetical protein 0.0059 0.0347 0.1383
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0058 0.0336 0.05
Toxoplasma gondii transporter, cation channel family protein 0.0059 0.0347 0.4115
Trichomonas vaginalis glucosylceramidase, putative 0.0233 0.1651 1
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0125 0.0844 0.1431
Mycobacterium tuberculosis Probable hydrolase 0.0125 0.0844 0.1431
Loa Loa (eye worm) hypothetical protein 0.0059 0.0347 0.1383
Schistosoma mansoni hypothetical protein 0.0255 0.1812 0.7221
Loa Loa (eye worm) hypothetical protein 0.0059 0.0347 0.1383
Echinococcus granulosus potassium voltage gated channel protein 0.0059 0.0347 0.0516
Schistosoma mansoni voltage-gated potassium channel 0.0059 0.0347 0.1383
Echinococcus multilocularis voltage dependent calcium channel 0.0059 0.0347 0.0347
Echinococcus granulosus calcium activated potassium channel 0.0059 0.0347 0.0516
Echinococcus multilocularis two pore calcium channel protein 1 0.0059 0.0347 0.0347
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0027 0.0106 0.0424
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0027 0.0106 0.0424
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0125 0.0844 0.1431
Echinococcus granulosus two pore calcium channel protein 2 0.0059 0.0347 0.0516
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0027 0.0106 0.0424
Echinococcus granulosus ryanodine receptor 44f 0.0059 0.0347 0.0516
Echinococcus multilocularis alpha 1,6 mannosyl glycoprotein 0.0348 0.251 0.251
Schistosoma mansoni vesicular amine transporter 0.0059 0.0347 0.1383
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0912 0.6725 1
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0173 0.1202 0.2039
Mycobacterium ulcerans aldehyde dehydrogenase 0.0058 0.0336 0.3149
Echinococcus granulosus shaker cognate 0.0059 0.0347 0.0516
Loa Loa (eye worm) voltage-dependent calcium channel 0.0059 0.0347 0.1383
Echinococcus granulosus mothers against decapentaplegic 5 0.0013 0.0004 0.0006
Echinococcus granulosus histone lysine methyltransferase setb 0.0027 0.0106 0.0158
Trichomonas vaginalis esterase, putative 0.0125 0.0844 0.4787
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0059 0.0347 0.4115
Mycobacterium ulcerans lipase LipD 0.0125 0.0844 1
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0059 0.0347 0.1383
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0059 0.0347 0.1383
Trypanosoma brucei PAB1-binding protein , putative 0.002 0.0053 0.0625
Brugia malayi hypothetical protein 0.0031 0.0138 0.0549
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0026 0.0103 0.041
Echinococcus granulosus SAM and MBT domain containing protein 0.004 0.0208 0.0309
Schistosoma mansoni transient receptor potential channel 0.0059 0.0347 0.1383
Plasmodium falciparum ataxin-2 like protein, putative 0.002 0.0053 0.1112
Brugia malayi N-terminal motif family protein 0.0141 0.0961 0.3827
Loa Loa (eye worm) hypothetical protein 0.0125 0.0844 0.3362
Echinococcus multilocularis histone acetyltransferase MYST2 0.0046 0.0249 0.0249
Loa Loa (eye worm) hypothetical protein 0.0059 0.0347 0.1383
Echinococcus granulosus GPCR family 2 0.0041 0.0215 0.0319
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0041 0.0215 0.0319
Toxoplasma gondii LsmAD domain-containing protein 0.002 0.0053 0.0625
Mycobacterium tuberculosis Probable dehydrogenase 0.0173 0.1202 0.2039
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0059 0.0347 0.0347
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0026 0.0103 0.2172
Echinococcus granulosus short transient receptor potential channel 6 0.0059 0.0347 0.0516
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0027 0.0106 0.126
Echinococcus multilocularis geminin 0.0255 0.1812 0.1812
Mycobacterium tuberculosis Probable oxidoreductase 0.0193 0.1347 0.2284
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0013 0.0004 0.0017
Brugia malayi Smad1 0.0013 0.0004 0.0017
Loa Loa (eye worm) hypothetical protein 0.0141 0.0961 0.3827
Echinococcus granulosus potassium voltage gated channel protein 0.0059 0.0347 0.0516
Leishmania major trypanothione reductase 0.0076 0.0474 0.0705
Loa Loa (eye worm) beta-lactamase 0.0125 0.0844 0.3362
Brugia malayi beta-lactamase family protein 0.0125 0.0844 0.3362
Trichomonas vaginalis D-aminoacylase, putative 0.0125 0.0844 0.4787
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0062 0.037 0.055
Echinococcus granulosus Smad4 0.0013 0.0004 0.0006
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0041 0.0215 0.0319
Trichomonas vaginalis glucosylceramidase, putative 0.0153 0.1051 0.6124
Echinococcus multilocularis two pore calcium channel protein 2 0.0059 0.0347 0.0347
Leishmania major hypothetical protein, unknown function 0.0059 0.0347 0.0516
Echinococcus granulosus sodium channel protein 0.0912 0.6725 1
Echinococcus granulosus hypothetical protein 0.0059 0.0347 0.0516
Schistosoma mansoni transient receptor potential channel 0.0059 0.0347 0.1383
Brugia malayi Pre-SET motif family protein 0.0187 0.1302 0.5186
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0059 0.0347 0.4115
Echinococcus multilocularis transient receptor potential cation channel 0.0059 0.0347 0.0347
Echinococcus granulosus voltage dependent calcium channel 0.0059 0.0347 0.0516
Brugia malayi Latrophilin receptor protein 2 0.0041 0.0215 0.0855
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0059 0.0347 0.0516
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0179 0.1244 0.4955
Loa Loa (eye worm) hypothetical protein 0.0041 0.0215 0.0855
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0059 0.0349 0.0519
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0173 0.1202 0.2039
Brugia malayi voltage-dependent calcium channel 0.0059 0.0347 0.1383
Echinococcus multilocularis transient receptor potential gamma protein 0.0059 0.0347 0.0347
Trichomonas vaginalis penicillin-binding protein, putative 0.0125 0.0844 0.4787
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0059 0.0347 0.0347
Echinococcus granulosus transcription factor Dp 1 0.0034 0.0162 0.0241
Schistosoma mansoni voltage-gated potassium channel 0.0059 0.0347 0.1383
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0059 0.0349 0.0519
Loa Loa (eye worm) voltage-gated calcium channel 0.0059 0.0347 0.1383
Schistosoma mansoni voltage-gated cation channel 0.0059 0.0347 0.1383
Brugia malayi MH1 domain containing protein 0.0013 0.0004 0.0017
Trypanosoma cruzi PAB1-binding protein , putative 0.002 0.0053 0.0625
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0026 0.0103 0.1221
Trypanosoma brucei hypothetical protein, conserved 0.0125 0.0844 1
Schistosoma mansoni voltage-gated potassium channel 0.0059 0.0347 0.1383
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0193 0.1347 0.2284
Brugia malayi ion channel NompC 0.0059 0.0347 0.1383
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0062 0.037 0.037
Plasmodium vivax hypothetical protein, conserved 0.0125 0.0844 1
Schistosoma mansoni voltage-gated potassium channel 0.0059 0.0347 0.1383
Echinococcus granulosus potassium large conductance calcium activated 0.0059 0.0347 0.0516
Echinococcus granulosus alpha 16 mannosyl glycoprotein 0.0348 0.251 0.3732
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0179 0.1244 0.4955
Brugia malayi cation channel family protein 0.0059 0.0347 0.1383
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0026 0.0103 0.1221
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0059 0.0347 0.4115
Schistosoma mansoni voltage-gated potassium channel 0.0059 0.0347 0.1383
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0059 0.0347 0.0347
Loa Loa (eye worm) hypothetical protein 0.0059 0.0347 0.1383
Echinococcus multilocularis ryanodine receptor 44f 0.0059 0.0347 0.0347
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0059 0.0347 0.4115
Mycobacterium tuberculosis Probable lipase LipE 0.0125 0.0844 0.1431
Echinococcus granulosus potassium voltage gated channel protein 0.0059 0.0347 0.0516
Echinococcus granulosus TGF beta signal transducer SmadC 0.0013 0.0004 0.0006
Trypanosoma brucei trypanothione reductase 0.0076 0.0474 0.5621
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0026 0.0103 0.1221
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0059 0.0347 0.0516
Schistosoma mansoni hypothetical protein 0.0059 0.0347 0.1383
Schistosoma mansoni smad1 5 8 and 0.0013 0.0004 0.0017
Echinococcus granulosus transient receptor potential cation channel 0.0059 0.0347 0.0516
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0059 0.0347 0.1383
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0013 0.0004 0.0004
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0046 0.0249 0.0371
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0062 0.037 0.055
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0062 0.037 0.1474
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0041 0.0215 0.0215
Echinococcus multilocularis sodium leak channel non selective protein 0.0059 0.0347 0.0347
Schistosoma mansoni 60S ribosomal protein L21 0.0059 0.0347 0.1383
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0059 0.0347 0.0516
Echinococcus multilocularis transient receptor potential cation channel 0.0059 0.0347 0.0347
Leishmania major hypothetical protein, conserved 0.0059 0.0347 0.0516
Mycobacterium tuberculosis Probable esterase LipL 0.0125 0.0844 0.1431
Trichomonas vaginalis set domain proteins, putative 0.0212 0.1495 0.8992
Toxoplasma gondii hypothetical protein 0.0059 0.0347 0.4115
Plasmodium falciparum thioredoxin reductase 0.0076 0.0474 1
Echinococcus multilocularis Smad4 0.0013 0.0004 0.0004
Brugia malayi beta-lactamase 0.0125 0.0844 0.3362
Schistosoma mansoni sex comb on midleg homolog 0.004 0.0208 0.0827
Schistosoma mansoni aldehyde dehydrogenase 0.0058 0.0336 0.134
Mycobacterium tuberculosis Probable reductase 0.0173 0.1202 0.2039
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0059 0.0347 0.0516
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0912 0.6725 1
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0059 0.0347 0.0516
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0062 0.037 0.1725
Onchocerca volvulus 0.004 0.0208 0.073
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0173 0.1202 0.7124
Echinococcus multilocularis thioredoxin glutathione reductase 0.0076 0.0474 0.0474
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0031 0.0138 0.0205
Echinococcus multilocularis SAM and MBT domain containing protein 0.004 0.0208 0.0208
Echinococcus granulosus transient receptor potential cation channel 0.0059 0.0347 0.0516
Trypanosoma cruzi trypanothione reductase, putative 0.0076 0.0474 0.5621
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0059 0.0349 0.139
Loa Loa (eye worm) Smad1 0.0013 0.0004 0.0017
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0125 0.0844 0.1431
Loa Loa (eye worm) hypothetical protein 0.0046 0.0249 0.0994
Loa Loa (eye worm) MBCTL1 0.0046 0.0249 0.0994
Echinococcus multilocularis GPCR, family 2 0.0041 0.0215 0.0215
Echinococcus granulosus voltage gated potassium channel 0.0062 0.037 0.055
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0179 0.1244 0.4955
Toxoplasma gondii NADPH-glutathione reductase 0.0026 0.0103 0.1221
Trichomonas vaginalis glucosylceramidase, putative 0.0233 0.1651 1
Loa Loa (eye worm) hypothetical protein 0.0125 0.0844 0.3362
Schistosoma mansoni voltage-gated potassium channel 0.0059 0.0347 0.1383
Plasmodium vivax SET domain protein, putative 0.0027 0.0106 0.126
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0059 0.0347 0.0516
Echinococcus granulosus thioredoxin glutathione reductase 0.0076 0.0474 0.0705
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0059 0.0347 0.0516
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0059 0.0347 0.0516
Echinococcus granulosus smad 0.0013 0.0004 0.0006
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0059 0.0349 0.4134
Loa Loa (eye worm) hypothetical protein 0.0059 0.0347 0.1383
Echinococcus granulosus short transient receptor potential channel 6 0.0059 0.0347 0.0516
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0179 0.1244 0.1849
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0059 0.0347 0.0347
Brugia malayi cation channel family protein 0.0059 0.0347 0.1383
Onchocerca volvulus 0.0125 0.0844 0.5312
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0041 0.0215 0.0855
Loa Loa (eye worm) hypothetical protein 0.0062 0.037 0.1474
Echinococcus granulosus polycomb protein SCMH1 0.004 0.0208 0.0309
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0026 0.0103 0.1221
Trypanosoma cruzi hypothetical protein, conserved 0.0125 0.0844 1
Loa Loa (eye worm) hypothetical protein 0.0059 0.0347 0.1383
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.0103 0.1221
Echinococcus granulosus transient receptor potential gamma protein 0.0059 0.0347 0.0516
Mycobacterium tuberculosis Conserved protein 0.0125 0.0844 0.1431
Trichomonas vaginalis glucosylceramidase, putative 0.0233 0.1651 1
Schistosoma mansoni beta-12-n-acetylglucosaminyltransferase II 0.0348 0.251 1
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0125 0.0844 0.3362
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0062 0.037 0.055
Echinococcus multilocularis potassium voltage gated channel protein 0.0059 0.0347 0.0347
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0125 0.0844 0.3362
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0059 0.0347 0.1383
Echinococcus multilocularis transient receptor potential cation channel 0.0059 0.0347 0.0347
Echinococcus granulosus TRP transient receptor potential channel 0.0059 0.0347 0.0516
Schistosoma mansoni voltage-gated potassium channel 0.0059 0.0347 0.1383
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0059 0.0349 1
Loa Loa (eye worm) hypothetical protein 0.0059 0.0347 0.1383
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0026 0.0103 0.1221
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0059 0.0347 0.1383
Schistosoma mansoni aldehyde dehydrogenase 0.0058 0.0336 0.134
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0141 0.0961 0.6153
Brugia malayi MH1 domain containing protein 0.0013 0.0004 0.0017
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0233 0.1651 0.6576
Loa Loa (eye worm) hypothetical protein 0.0059 0.0347 0.1383
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0179 0.1244 0.1244
Plasmodium vivax ataxin-2 like protein, putative 0.002 0.0053 0.0625
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.013 0.0881 0.3509
Echinococcus granulosus hyperpolarization activated cyclic 0.0062 0.037 0.055
Mycobacterium tuberculosis Conserved protein 0.0125 0.0844 0.1431
Echinococcus multilocularis short transient receptor potential channel 6 0.0059 0.0347 0.0347
Echinococcus granulosus transient receptor potential cation channel 0.0059 0.0347 0.0516
Leishmania major hypothetical protein, conserved 0.0125 0.0844 0.1255
Brugia malayi hypothetical protein 0.002 0.0053 0.021
Brugia malayi MH2 domain containing protein 0.0013 0.0004 0.0017
Schistosoma mansoni smad1 5 8 and 0.0013 0.0004 0.0017
Echinococcus granulosus voltage gated potassium channel 0.0059 0.0347 0.0516
Schistosoma mansoni hypothetical protein 0.0031 0.0138 0.0549
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0059 0.0347 0.1383
Brugia malayi Cyclic-nucleotide gated cation channel 0.0062 0.037 0.1474
Loa Loa (eye worm) hypothetical protein 0.002 0.0053 0.021
Loa Loa (eye worm) hypothetical protein 0.0059 0.0347 0.1383
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0058 0.0336 0.0336
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0026 0.0103 0.5
Loa Loa (eye worm) ryanodine receptor 0.0059 0.0347 0.1383
Loa Loa (eye worm) voltage-gated potassium channel 0.0059 0.0347 0.1383
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0062 0.037 0.1474
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0059 0.0347 0.0347
Toxoplasma gondii transporter, cation channel family protein 0.0059 0.0347 0.4115
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0026 0.0103 0.041
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0059 0.0347 0.1383
Onchocerca volvulus 0.0125 0.0844 0.5312
Brugia malayi mbt repeat family protein 0.004 0.0208 0.0827
Echinococcus multilocularis smad 0.0013 0.0004 0.0004
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0125 0.0844 0.3362
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0062 0.037 0.1474
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0026 0.0103 0.0175
Echinococcus multilocularis potassium voltage gated channel protein 0.0059 0.0347 0.0347
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0026 0.0103 0.0153
Schistosoma mansoni voltage-gated ion channel 0.0059 0.0347 0.1383
Schistosoma mansoni ryanodine receptor related 0.0059 0.0347 0.1383
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0027 0.0106 0.0106
Brugia malayi Thioredoxin reductase 0.0076 0.0474 0.1889
Toxoplasma gondii hypothetical protein 0.0059 0.0347 0.4115
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0059 0.0347 0.1383
Mycobacterium tuberculosis Probable lipase LipD 0.0125 0.0844 0.1431
Loa Loa (eye worm) voltage-gated potassium channel 0.0059 0.0347 0.1383
Toxoplasma gondii aldehyde dehydrogenase 0.0058 0.0336 0.3985
Loa Loa (eye worm) hypothetical protein 0.0059 0.0347 0.1383
Brugia malayi hypothetical protein 0.0059 0.0347 0.1383
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0059 0.0347 0.0516
Echinococcus multilocularis potassium voltage gated channel protein 0.0059 0.0347 0.0347
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0062 0.037 0.1725
Echinococcus granulosus two pore calcium channel protein 1 0.0059 0.0347 0.0516
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.0103 0.1221
Loa Loa (eye worm) hypothetical protein 0.0059 0.0347 0.1383
Trichomonas vaginalis D-aminoacylase, putative 0.0125 0.0844 0.4787
Schistosoma mansoni voltage-gated potassium channel 0.0062 0.037 0.1474
Brugia malayi Transient-receptor-potential like protein 0.0059 0.0347 0.1383
Trichomonas vaginalis glucosylceramidase, putative 0.0161 0.1112 0.6522
Echinococcus multilocularis conserved hypothetical protein 0.0059 0.0347 0.0347
Echinococcus multilocularis voltage dependent calcium channel 0.0059 0.0347 0.0347
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0059 0.0349 0.139
Plasmodium falciparum ataxin-2 like protein, putative 0.002 0.0053 0.1112
Plasmodium falciparum glutathione reductase 0.0076 0.0474 1
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0059 0.0347 0.1383
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.004 0.0208 0.0827
Schistosoma mansoni hypothetical protein 0.0041 0.0215 0.0855
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0058 0.0336 0.05
Loa Loa (eye worm) hypothetical protein 0.0059 0.0347 0.1383
Loa Loa (eye worm) thioredoxin reductase 0.0076 0.0474 0.1889
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0059 0.0347 0.1383
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0059 0.0347 0.1383
Echinococcus granulosus voltage dependent calcium channel 0.0059 0.0347 0.0516
Echinococcus granulosus beta LACTamase domain containing family member 0.0125 0.0844 0.1255
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0179 0.1244 0.4955
Loa Loa (eye worm) MH1 domain-containing protein 0.0013 0.0004 0.0017
Mycobacterium ulcerans hypothetical protein 0.0125 0.0844 1
Echinococcus multilocularis shaker cognate 0.0059 0.0347 0.0347
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0076 0.0474 0.0804
Trichomonas vaginalis glucosylceramidase, putative 0.0233 0.1651 1
Toxoplasma gondii ABC1 family protein 0.0125 0.0844 1
Loa Loa (eye worm) hypothetical protein 0.0059 0.0347 0.1383
Brugia malayi latrophilin 2 splice variant baaae 0.0089 0.0572 0.2281
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0059 0.0347 0.1736
Trichomonas vaginalis penicillin-binding protein, putative 0.0125 0.0844 0.4787
Echinococcus multilocularis beta LACTamase domain containing family member 0.0125 0.0844 0.0844
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0179 0.1244 0.1244
Mycobacterium ulcerans beta-lactamase 0.0125 0.0844 1
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0125 0.0844 0.3362
Schistosoma mansoni transient receptor potential channel 4 0.0059 0.0347 0.1383
Echinococcus multilocularis potassium voltage gated channel protein 0.0059 0.0347 0.0347
Loa Loa (eye worm) glutathione reductase 0.0076 0.0474 0.1889
Loa Loa (eye worm) hypothetical protein 0.004 0.0208 0.0827
Schistosoma mansoni calcium-activated potassium channel 0.0059 0.0347 0.1383
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0159 0.1094 0.1627
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0179 0.1244 0.4955
Schistosoma mansoni hypothetical protein 0.0255 0.1812 0.7221
Brugia malayi MH2 domain containing protein 0.0013 0.0004 0.0017
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0059 0.0347 0.4115
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0062 0.037 0.1474
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0062 0.037 0.037
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.0103 0.1221
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0062 0.037 0.1474
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0059 0.0347 0.0347
Schistosoma mansoni hypothetical protein 0.0041 0.0215 0.0855
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0031 0.0138 0.0138
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0193 0.1347 1
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0058 0.0336 0.057
Loa Loa (eye worm) hypothetical protein 0.0125 0.0844 0.3362
Loa Loa (eye worm) hypothetical protein 0.0059 0.0347 0.1383
Schistosoma mansoni transient receptor potential channel 0.0059 0.0347 0.1383
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0062 0.037 0.1474
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0026 0.0103 0.1221
Schistosoma mansoni two-pore calcium channel 0.0059 0.0347 0.1383
Schistosoma mansoni transcription factor LCR-F1 0.0031 0.0138 0.0549
Plasmodium vivax thioredoxin reductase, putative 0.0076 0.0474 0.5621
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0062 0.037 0.1474
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0026 0.0103 0.1221
Trichomonas vaginalis glucosylceramidase, putative 0.0153 0.1051 0.6124
Loa Loa (eye worm) hypothetical protein 0.0125 0.0844 0.3362
Trichomonas vaginalis glucosylceramidase, putative 0.0153 0.1051 0.6124
Loa Loa (eye worm) hypothetical protein 0.0062 0.037 0.1474
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0026 0.0099 0.0147
Brugia malayi mbt repeat family protein 0.004 0.0208 0.0827
Echinococcus multilocularis potassium large conductance calcium activated 0.0059 0.0347 0.0347
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0059 0.0347 0.1383
Loa Loa (eye worm) latrophilin receptor protein 2 0.0041 0.0215 0.0855
Schistosoma mansoni hypothetical protein 0.0041 0.0215 0.0855
Echinococcus granulosus geminin 0.0255 0.1812 0.2695
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0059 0.0347 0.0347
Schistosoma mansoni voltage-gated potassium channel 0.0062 0.037 0.1474
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0027 0.0106 0.0106
Echinococcus granulosus voltage gated hydrogen channel 1 0.0059 0.0347 0.0516
Toxoplasma gondii transporter, cation channel family protein 0.0059 0.0347 0.4115
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0059 0.0347 0.0347
Echinococcus granulosus transient receptor potential cation channel 0.0059 0.0347 0.0516
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0019 0.0051 0.0202
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0059 0.0347 0.1383
Loa Loa (eye worm) hypothetical protein 0.0059 0.0347 0.1383
Echinococcus multilocularis transient receptor potential cation channel 0.0059 0.0347 0.0347
Loa Loa (eye worm) mbt repeat family protein 0.004 0.0208 0.0827
Schistosoma mansoni voltage-gated potassium channel 0.0059 0.0347 0.1383
Schistosoma mansoni hypothetical protein 0.0089 0.0572 0.2281
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0801 0.5897 1
Schistosoma mansoni voltage-gated potassium channel 0.0059 0.0347 0.1383
Mycobacterium ulcerans esterase/lipase LipP 0.0125 0.0844 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.0103 0.1221
Brugia malayi Pre-SET motif family protein 0.0027 0.0106 0.0424
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.0103 0.1221
Loa Loa (eye worm) MH2 domain-containing protein 0.0193 0.1347 0.5366
Schistosoma mansoni myelin transcription factor 1 myt1 0.0046 0.0249 0.0994
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0062 0.037 0.1474
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0062 0.037 0.037
Schistosoma mansoni sex comb on midleg homolog 0.004 0.0208 0.0827
Schistosoma mansoni smad1 5 8 and 0.0013 0.0004 0.0017
Loa Loa (eye worm) hypothetical protein 0.0059 0.0347 0.1383
Schistosoma mansoni voltage-gated potassium channel 0.0059 0.0347 0.1383
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0026 0.0103 0.0153
Schistosoma mansoni voltage-gated potassium channel 0.0059 0.0347 0.1383
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0179 0.1244 0.1849
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0059 0.0347 0.1383
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0059 0.0347 0.1383
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0059 0.0347 0.1383
Echinococcus multilocularis calcium activated potassium channel 0.0059 0.0347 0.0347
Echinococcus granulosus potassium voltage gated channel protein 0.0059 0.0347 0.0516
Echinococcus multilocularis hyperpolarization activated cyclic 0.0062 0.037 0.037
Schistosoma mansoni hypothetical protein 0.0041 0.0215 0.0855
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0059 0.0349 0.139
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0059 0.0347 0.1383
Echinococcus granulosus transient receptor potential cation channel 0.0059 0.0347 0.0516
Trichomonas vaginalis glucosylceramidase, putative 0.0233 0.1651 1
Loa Loa (eye worm) hypothetical protein 0.0125 0.0844 0.3362
Mycobacterium tuberculosis Conserved protein 0.0125 0.0844 0.1431
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0059 0.0347 0.1736
Loa Loa (eye worm) hypothetical protein 0.013 0.0881 0.3509
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0026 0.0103 0.0153
Onchocerca volvulus 0.0212 0.1495 1
Echinococcus granulosus sodium leak channel non selective protein 0.0059 0.0347 0.0516
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0062 0.037 0.055
Loa Loa (eye worm) hypothetical protein 0.0059 0.0347 0.1383
Trypanosoma cruzi PAB1-binding protein , putative 0.002 0.0053 0.0625
Trichomonas vaginalis glucosylceramidase, putative 0.0153 0.1051 0.6124
Schistosoma mansoni voltage-gated potassium channel 0.0059 0.0347 0.1383
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0041 0.0215 0.0215
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0059 0.0347 0.1383
Loa Loa (eye worm) hypothetical protein 0.0125 0.0844 0.3362
Echinococcus multilocularis transient receptor potential cation channel 0.0059 0.0347 0.0347
Trichomonas vaginalis glucosylceramidase, putative 0.0233 0.1651 1
Schistosoma mansoni voltage-gated potassium channel 0.0059 0.0347 0.1383
Loa Loa (eye worm) hypothetical protein 0.0089 0.0572 0.2281
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0059 0.0347 0.1383
Trichomonas vaginalis glucosylceramidase, putative 0.0153 0.1051 0.6124
Treponema pallidum NADH oxidase 0.0026 0.0103 0.5
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0026 0.0103 0.1221
Schistosoma mansoni voltage-gated potassium channel 0.0062 0.037 0.1474
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0059 0.0349 0.4134
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0187 0.1302 0.5186
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0026 0.0103 0.5
Loa Loa (eye worm) hypothetical protein 0.0027 0.0106 0.0424
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0046 0.0249 0.0994
Loa Loa (eye worm) hypothetical protein 0.0059 0.0347 0.1383
Loa Loa (eye worm) hypothetical protein 0.0348 0.251 1
Echinococcus multilocularis transient receptor potential cation channel 0.0059 0.0347 0.0347
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0059 0.0347 0.1383
Loa Loa (eye worm) MH2 domain-containing protein 0.0013 0.0004 0.0017
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.0103 0.1221
Giardia lamblia NADH oxidase lateral transfer candidate 0.0026 0.0103 0.5
Loa Loa (eye worm) hypothetical protein 0.0059 0.0347 0.1383
Echinococcus multilocularis sodium channel protein 0.0912 0.6725 0.6725
Echinococcus multilocularis transcription factor Dp 1 0.0034 0.0162 0.0162
Echinococcus multilocularis voltage gated potassium channel 0.0059 0.0347 0.0347
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0059 0.0347 0.1383
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0062 0.037 0.055
Brugia malayi UDP-GlcNAc:a-6-D-mannoside b1,2-N-acetylglucosaminyltransferase II 0.0348 0.251 1
Toxoplasma gondii thioredoxin reductase 0.0076 0.0474 0.5621
Trypanosoma cruzi trypanothione reductase, putative 0.0026 0.0103 0.1221
Trypanosoma cruzi hypothetical protein, conserved 0.0125 0.0844 1
Leishmania major hypothetical protein, conserved 0.002 0.0053 0.0078
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0027 0.0106 0.0424
Schistosoma mansoni voltage-gated potassium channel 0.0062 0.037 0.1474
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0026 0.0103 0.0153
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0046 0.0249 0.0249
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0062 0.037 0.037
Loa Loa (eye worm) ion channel NompC 0.0059 0.0347 0.1383
Brugia malayi olfactory channel protein osm-9 0.0059 0.0347 0.1383
Mycobacterium ulcerans aldehyde dehydrogenase 0.0058 0.0336 0.3149
Loa Loa (eye worm) pigment dispersing factor receptor c 0.013 0.0881 0.3509
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0059 0.0347 0.1383
Schistosoma mansoni Smad4 0.0013 0.0004 0.0017
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0059 0.0347 0.0347
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0059 0.0347 0.0516
Loa Loa (eye worm) calcium channel 0.0059 0.0347 0.1383
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0059 0.0347 0.0347
Echinococcus multilocularis hyperpolarization activated cyclic 0.0062 0.037 0.037
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.004 0.0208 0.073
Plasmodium falciparum thioredoxin reductase 0.0026 0.0103 0.2172
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0026 0.0103 0.1221
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0019 0.0051 0.0202
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0062 0.037 0.037
Brugia malayi MH2 domain containing protein 0.0193 0.1347 0.5366
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0173 0.1202 0.2039
Plasmodium falciparum glutathione reductase 0.0026 0.0103 0.2172
Echinococcus multilocularis transfer RNA-Gly 0.0059 0.0347 0.0347
Schistosoma mansoni voltage-dependent calcium channel 0.0059 0.0347 0.1383
Trichomonas vaginalis glucosylceramidase, putative 0.0153 0.1051 0.6124
Echinococcus granulosus histone acetyltransferase MYST2 0.0046 0.0249 0.0371
Trichomonas vaginalis glucosylceramidase, putative 0.0161 0.1112 0.6522
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0059 0.0347 0.1383
Echinococcus multilocularis voltage gated potassium channel 0.0062 0.037 0.037
Brugia malayi Calcitonin receptor-like protein seb-1 0.013 0.0881 0.3509
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0026 0.0103 0.5
Echinococcus multilocularis polycomb protein SCMH1 0.004 0.0208 0.0208
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0026 0.0103 0.2172
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0062 0.037 0.055
Echinococcus granulosus hyperpolarization activated cyclic 0.0062 0.037 0.055
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0193 0.1347 0.2284
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0059 0.0349 0.4134
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0059 0.0347 0.1383
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0125 0.0844 1
Onchocerca volvulus 0.0059 0.0347 0.1736
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0059 0.0347 0.4115
Loa Loa (eye worm) transcription factor SMAD2 0.0193 0.1347 0.5366
Echinococcus granulosus transient receptor potential cation channel 0.0059 0.0347 0.0516
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0059 0.0347 0.1383
Schistosoma mansoni voltage-gated potassium channel 0.0062 0.037 0.1474
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0233 0.1651 0.6576
Trichomonas vaginalis D-aminoacylase, putative 0.0125 0.0844 0.4787

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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