Detailed information for compound 1614109

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 277.359 | Formula: C16H23NO3
  • H donors: 2 H acceptors: 2 LogP: 2.62 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(NC1CCCCC1O)COc1c(C)cccc1C
  • InChi: 1S/C16H23NO3/c1-11-6-5-7-12(2)16(11)20-10-15(19)17-13-8-3-4-9-14(13)18/h5-7,13-14,18H,3-4,8-10H2,1-2H3,(H,17,19)
  • InChiKey: MITSQXUHQXSFGT-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis signal transduction protein lnk realted 0.0021 0.0011 0.0004
Schistosoma mansoni tyrosine kinase 0.0047 0.0194 0.0189
Schistosoma mansoni hypothetical protein 0.0048 0.02 0.0195
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0021 0.0011 0.0004
Brugia malayi YY1-associated factor 2 0.0073 0.0373 0.0475
Echinococcus granulosus tyrosine protein kinase Src64B 0.0047 0.0194 0.0186
Echinococcus granulosus SH2 motif 0.0021 0.0011 0.0004
Loa Loa (eye worm) TK/FER protein kinase 0.0027 0.0052 0.0052
Brugia malayi SH2 domain containing protein 0.0021 0.0011 0.0005
Brugia malayi SH2 domain containing protein 0.0021 0.0011 0.0005
Echinococcus granulosus tyrosine protein kinase Srms 0.0027 0.0052 0.0044
Leishmania major hypothetical protein, conserved 0.0073 0.0373 1
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0021 0.0011 0.0011
Echinococcus multilocularis rab protein 3 0.0048 0.02 0.0192
Brugia malayi Protein kinase domain containing protein 0.1124 0.7686 1
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0047 0.0194 0.0186
Schistosoma mansoni vav2 0.0021 0.0011 0.0004
Schistosoma mansoni tensin-related 0.0021 0.0011 0.0004
Schistosoma mansoni brg-1 associated factor 0.0205 0.129 0.1302
Leishmania major hypothetical protein, conserved 0.0073 0.0373 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Echinococcus granulosus signal transduction protein lnk realted 0.0021 0.0011 0.0004
Echinococcus multilocularis ras-related protein rab-5 0.0048 0.02 0.0192
Brugia malayi brahma associated protein 60 kDa 0.0205 0.129 0.167
Schistosoma mansoni tensin 0.0021 0.0011 0.0004
Brugia malayi SWIB/MDM2 domain containing protein 0.0205 0.129 0.167
Trypanosoma cruzi Rab-like 5, small G protein 0.0048 0.02 0.5265
Onchocerca volvulus 0.0027 0.0052 0.0331
Onchocerca volvulus Ubiquitin thioesterase ZRANB1 homolog 0.0073 0.0373 0.2722
Trypanosoma cruzi Zn-finger in Ran binding protein and others/FYVE zinc finger, putative 0.0073 0.0373 1
Plasmodium vivax SWIB/MDM2 domain-containing protein, putative 0.0205 0.129 1
Schistosoma mansoni growth factor receptor-bound protein 0.0041 0.0153 0.0147
Echinococcus granulosus tyrosine protein kinase Fyn 0.0047 0.0194 0.0186
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.0021 0.0011 0.0027
Loa Loa (eye worm) hypothetical protein 0.0021 0.0011 0.0011
Schistosoma mansoni nck2/grb4 0.0041 0.0153 0.0147
Loa Loa (eye worm) hypothetical protein 0.0021 0.0011 0.0011
Echinococcus multilocularis tensin 0.0021 0.0011 0.0004
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0021 0.0011 0.0004
Entamoeba histolytica SH2 domain containing protein 0.0021 0.0011 0.0188
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0021 0.0011 0.0004
Loa Loa (eye worm) TK protein kinase 0.0027 0.0052 0.0052
Onchocerca volvulus 0.0073 0.0373 0.2722
Brugia malayi Tyrosine-protein kinase abl-1 0.0883 0.601 0.7818
Loa Loa (eye worm) cytochrome P450 family protein 0.0027 0.0054 0.0054
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0047 0.0194 0.0186
Onchocerca volvulus Mitochondrial Rho GTPase homolog 0.0048 0.02 0.1433
Echinococcus granulosus ring and YY1 binding protein 0.0073 0.0373 0.0365
Trypanosoma cruzi mitochondrial RNA binding complex 1 subunit, putative 0.0073 0.0373 1
Loa Loa (eye worm) hypothetical protein 0.0553 0.3711 0.3711
Loa Loa (eye worm) hypothetical protein 0.0048 0.02 0.02
Trypanosoma cruzi hypothetical protein, conserved 0.0048 0.02 0.5265
Brugia malayi Ras-related protein ypt4 0.0048 0.02 0.025
Trypanosoma brucei Zn-finger in Ran binding protein and others/FYVE zinc finger, putative 0.0073 0.0373 1
Trypanosoma cruzi cytochrome P450, putative 0.0027 0.0054 0.1267
Brugia malayi SH2 domain containing protein 0.0027 0.0052 0.0058
Brugia malayi Tyrosine-protein kinase abl-1 0.0594 0.3997 0.5196
Loa Loa (eye worm) SRC-1 0.0047 0.0194 0.0194
Loa Loa (eye worm) protein-tyrosine kinase 0.002 0.0008 0.0008
Echinococcus multilocularis 0.0021 0.0011 0.0004
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0047 0.0194 0.0186
Leishmania major hypothetical protein, conserved 0.0048 0.02 0.5265
Onchocerca volvulus 0.0021 0.0011 0.0027
Brugia malayi SH2 domain containing protein 0.0021 0.0011 0.0005
Plasmodium vivax hypothetical protein, conserved 0.0205 0.129 1
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0047 0.0194 0.0186
Leishmania major hypothetical protein, conserved 0.0073 0.0373 1
Loa Loa (eye worm) SH2 domain-containing protein 0.0021 0.0011 0.0011
Echinococcus multilocularis Nuclear pore complex protein Nup153 0.0073 0.0373 0.0365
Brugia malayi SH2 domain containing protein 0.0021 0.0011 0.0005
Echinococcus granulosus SH2 domain containing protein 7 0.0021 0.0011 0.0004
Echinococcus granulosus tyrosine protein kinase Blk 0.0027 0.0052 0.0044
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0021 0.0011 0.0004
Schistosoma mansoni tyrosine kinase 0.0027 0.0052 0.0045
Leishmania major hypothetical protein, conserved 0.0048 0.02 0.5265
Loa Loa (eye worm) hypothetical protein 0.0021 0.0011 0.0011
Onchocerca volvulus 0.0027 0.0052 0.0331
Schistosoma mansoni suppressor of cytokine signaling 0.0021 0.0011 0.0004
Echinococcus multilocularis zinc finger protein Ran binding 0.0073 0.0373 0.0365
Schistosoma mansoni tensin 0.0021 0.0011 0.0004
Loa Loa (eye worm) hypothetical protein 0.0048 0.02 0.02
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0021 0.0011 0.0011
Loa Loa (eye worm) TKL/LRRK protein kinase 0.1124 0.7686 0.7686
Loa Loa (eye worm) TK/FER protein kinase 0.0027 0.0052 0.0052
Trichomonas vaginalis conserved hypothetical protein 0.0205 0.129 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0011 0.0011
Echinococcus multilocularis SWI:SNF matrix associated 0.0205 0.129 0.1284
Leishmania major hypothetical protein, conserved 0.0073 0.0373 1
Echinococcus multilocularis SHC transforming protein 3 0.0021 0.0011 0.0004
Onchocerca volvulus 0.0213 0.1349 1
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0021 0.0011 0.0011
Echinococcus granulosus tensin 0.0021 0.0011 0.0004
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0021 0.0011 0.0004
Trypanosoma brucei cytochrome P450, putative 0.0027 0.0054 0.1267
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0047 0.0194 0.0186
Trypanosoma brucei hypothetical protein, conserved 0.0073 0.0373 1
Brugia malayi Variant SH3 domain containing protein 0.0021 0.0011 0.0005
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0021 0.0011 0.0004
Echinococcus granulosus tyrosine kinase 0.0027 0.0052 0.0044
Schistosoma mansoni hypothetical protein 0.0205 0.129 0.1302
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0073 0.0373 0.0475
Brugia malayi RAB, member of RAS oncogene family-like 5 0.0048 0.02 0.025
Echinococcus multilocularis Zinc finger, RanBP2 type 0.0073 0.0373 0.0365
Echinococcus multilocularis GTP binding protein Parf 0.0048 0.02 0.0192
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0047 0.0194 0.0186
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0047 0.0194 0.0189
Brugia malayi Tensin 0.0021 0.0011 0.0005
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0027 0.0052 0.0044
Echinococcus multilocularis SH2 motif 0.0021 0.0011 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.02 0.1498
Echinococcus multilocularis SH2 domain containing protein 7 0.0021 0.0011 0.0004
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0021 0.0011 0.0004
Loa Loa (eye worm) thyroid receptor interactor 0.002 0.0008 0.0008
Echinococcus granulosus tyrosine protein kinase shark 0.0027 0.0052 0.0044
Trypanosoma cruzi Zn-finger in Ran binding protein and others, putative 0.0073 0.0373 1
Echinococcus multilocularis SWI:SNF matrix associated 0.0205 0.129 0.1284
Brugia malayi hypothetical protein 0.0048 0.02 0.025
Brugia malayi SH2 domain containing protein 0.0021 0.0011 0.0005
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.0205 0.129 1
Chlamydia trachomatis SWIB complex protein 0.0205 0.129 0.5
Loa Loa (eye worm) hypothetical protein 0.0048 0.02 0.02
Brugia malayi Cytochrome P450 family protein 0.0027 0.0054 0.006
Loa Loa (eye worm) TK/FER protein kinase 0.0027 0.0052 0.0052
Schistosoma mansoni fusion 0.0073 0.0373 0.0371
Echinococcus granulosus growth factor receptor bound protein 2 0.0041 0.0153 0.0145
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0047 0.0194 0.0186
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0047 0.0194 0.0186
Leishmania major cytochrome p450-like protein 0.0027 0.0054 0.1267
Loa Loa (eye worm) SH2 domain-containing protein 0.0021 0.0011 0.0011
Brugia malayi Protein kinase domain containing protein 0.0027 0.0052 0.0058
Brugia malayi Protein kinase domain containing protein 0.0027 0.0052 0.0058
Brugia malayi Variant SH3 domain containing protein 0.0041 0.0153 0.0189
Echinococcus granulosus tyrosine kinase 0.0027 0.0052 0.0044
Loa Loa (eye worm) hypothetical protein 0.0021 0.0011 0.0011
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0021 0.0011 0.0005
Schistosoma mansoni suppressor of cytokine signaling 0.0021 0.0011 0.0004
Echinococcus granulosus tyrosine protein kinase Fyn 0.0047 0.0194 0.0186
Loa Loa (eye worm) p53BP2 0.002 0.0008 0.0008
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0021 0.0011 0.0004
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0041 0.0153 0.0147
Loa Loa (eye worm) hypothetical protein 0.0021 0.0011 0.0011
Echinococcus granulosus Zinc finger RanBP2 type 0.0073 0.0373 0.0365
Echinococcus granulosus SH2 domain containing adapter protein F 0.0021 0.0011 0.0004
Trypanosoma cruzi cytochrome P450, putative 0.0027 0.0054 0.1267
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0047 0.0194 0.0186
Echinococcus multilocularis c src tyrosine kinase 0.0047 0.0194 0.0186
Echinococcus granulosus tyrosine protein kinase Src42A 0.0047 0.0194 0.0186
Echinococcus granulosus suppressor of cytokine signaling 6 0.0021 0.0011 0.0004
Brugia malayi Variant SH3 domain containing protein 0.0021 0.0011 0.0005
Loa Loa (eye worm) hypothetical protein 0.0021 0.0011 0.0011
Onchocerca volvulus 0.0073 0.0373 0.2722
Echinococcus granulosus tumor protein p63 0.1456 0.9994 0.9994
Brugia malayi tRNA modification GTPase TrmE family protein 0.0021 0.0011 0.0005
Echinococcus granulosus tyrosine protein kinase Fyn 0.0047 0.0194 0.0186
Echinococcus granulosus tyrosine protein kinase Lyn 0.005 0.0214 0.0207
Loa Loa (eye worm) hypothetical protein 0.0027 0.0052 0.0052
Echinococcus granulosus SWI:SNF matrix associated 0.0205 0.129 0.1284
Schistosoma mansoni tyrosine kinase 0.0027 0.0052 0.0045
Loa Loa (eye worm) hypothetical protein 0.0021 0.0011 0.0011
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0027 0.0052 0.2309
Echinococcus multilocularis ring and YY1 binding protein 0.0073 0.0373 0.0365
Schistosoma mansoni hypothetical protein 0.0073 0.0373 0.0371
Trypanosoma cruzi hypothetical protein, conserved 0.0048 0.02 0.5265
Echinococcus granulosus leucine rich repeat serine:threonine protein 0.1132 0.7739 0.7737
Loa Loa (eye worm) variant SH3 domain-containing protein 0.002 0.0008 0.0008
Schistosoma mansoni hypothetical protein 0.0021 0.0011 0.0004
Onchocerca volvulus 0.0205 0.129 0.9566
Brugia malayi Protein kinase domain containing protein 0.0027 0.0052 0.0058
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0027 0.0052 0.0044
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0021 0.0011 0.0011
Entamoeba histolytica protein kinase, putative 0.0024 0.0032 0.1262
Loa Loa (eye worm) hypothetical protein 0.0073 0.0373 0.0373
Loa Loa (eye worm) hypothetical protein 0.0021 0.0011 0.0011
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0073 0.0373 0.0475
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Onchocerca volvulus 0.0048 0.02 0.1433
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0021 0.0011 0.0004
Trypanosoma brucei hypothetical protein, conserved 0.0073 0.0373 1
Onchocerca volvulus 0.0021 0.0011 0.0027
Onchocerca volvulus 0.0027 0.0052 0.0331
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0021 0.0011 0.0004
Loa Loa (eye worm) hypothetical protein 0.0073 0.0373 0.0373
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0047 0.0194 0.0186
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0047 0.0194 0.0186
Loa Loa (eye worm) hypothetical protein 0.0073 0.0373 0.0373
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0021 0.0011 0.0004
Trypanosoma cruzi hypothetical protein, conserved 0.0048 0.02 0.5265
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0021 0.0011 0.0004
Loa Loa (eye worm) brahma associated protein 0.0205 0.129 0.129
Echinococcus granulosus GTP binding protein Parf 0.0048 0.02 0.0192
Echinococcus multilocularis tensin 0.0021 0.0011 0.0004
Echinococcus granulosus suppressor of cytokine signaling 7 0.0021 0.0011 0.0004
Echinococcus granulosus hypothetical protein 0.0021 0.0011 0.0004
Schistosoma mansoni cellular tumor antigen P53 0.0213 0.1349 0.1362
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Schistosoma mansoni tensin 0.0021 0.0011 0.0004
Brugia malayi hypothetical protein 0.0027 0.0052 0.0058
Brugia malayi protein-tyrosine kinase 0.0027 0.0052 0.0058
Toxoplasma gondii SWIB/MDM2 domain-containing protein 0.0205 0.129 1
Echinococcus granulosus expressed conserved protein 0.0021 0.0011 0.0004
Loa Loa (eye worm) hypothetical protein 0.0021 0.0011 0.0011
Schistosoma mansoni RNA binding protein 0.0073 0.0373 0.0371
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0041 0.0153 0.0153
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0027 0.0052 0.0044
Loa Loa (eye worm) hypothetical protein 0.0021 0.0011 0.0011
Echinococcus multilocularis tyrosine protein kinase shark 0.0027 0.0052 0.0044
Onchocerca volvulus 0.0027 0.0052 0.0331
Entamoeba histolytica hypothetical protein 0.0048 0.02 1
Loa Loa (eye worm) protein kinase C and casein kinase substrate in neurons protein 2 0.002 0.0008 0.0008
Loa Loa (eye worm) TK/FER protein kinase 0.0027 0.0052 0.0052
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.0373 1
Echinococcus granulosus SHC transforming protein 3 0.0021 0.0011 0.0004
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0047 0.0194 0.0186
Loa Loa (eye worm) hypothetical protein 0.0021 0.0011 0.0011
Echinococcus granulosus N chimaerin 0.0021 0.0011 0.0004
Schistosoma mansoni hypothetical protein 0.0021 0.0011 0.0004
Loa Loa (eye worm) TK/FER protein kinase 0.0027 0.0052 0.0052
Echinococcus multilocularis N chimaerin 0.0021 0.0011 0.0004
Loa Loa (eye worm) SH2 domain-containing protein 0.0021 0.0011 0.0011
Chlamydia trachomatis DNA topoisomerase I 0.0205 0.129 0.5
Onchocerca volvulus 0.0027 0.0052 0.0331
Loa Loa (eye worm) STAT protein 0.0021 0.0011 0.0011
Loa Loa (eye worm) TK/FER protein kinase 0.0027 0.0052 0.0052
Echinococcus multilocularis tyrosine kinase 0.0027 0.0052 0.0044
Echinococcus multilocularis SH2 motif 0.0021 0.0011 0.0004
Loa Loa (eye worm) hypothetical protein 0.0021 0.0011 0.0011
Brugia malayi SH2 domain containing protein 0.0021 0.0011 0.0005
Schistosoma mansoni tyrosine kinase 0.0047 0.0194 0.0189
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0021 0.0011 0.0004
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.0373 1
Echinococcus granulosus tyrosine protein kinase Src42A 0.0021 0.0011 0.0004
Brugia malayi RhoGAP domain containing protein 0.0021 0.0011 0.0005
Onchocerca volvulus 0.0023 0.0028 0.0154
Schistosoma mansoni shc transforming protein 0.0021 0.0011 0.0004
Schistosoma mansoni TRABID protein (C64 family) 0.0073 0.0373 0.0371
Brugia malayi SRC-1 0.0047 0.0194 0.0242
Loa Loa (eye worm) hypothetical protein 0.0213 0.1349 0.1349
Brugia malayi Protein kinase domain containing protein 0.0027 0.0052 0.0058
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.0373 1
Trypanosoma brucei Rab-like 5, small G protein 0.0048 0.02 0.5265
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Loa Loa (eye worm) TK/FER protein kinase 0.0027 0.0052 0.0052
Schistosoma mansoni tyrosine kinase 0.0047 0.0194 0.0189
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0047 0.0194 0.0186
Loa Loa (eye worm) hypothetical protein 0.0073 0.0373 0.0373
Loa Loa (eye worm) TK/FER protein kinase 0.0027 0.0052 0.0052
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.0205 0.129 1
Loa Loa (eye worm) CYP4Cod1 0.0027 0.0054 0.0054
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0021 0.0011 0.0004
Plasmodium falciparum zinc finger Ran-binding domain-containing protein 2, putative 0.0073 0.0373 0.1585
Loa Loa (eye worm) TK/FER protein kinase 0.0027 0.0052 0.0052
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0021 0.0011 0.0004
Entamoeba histolytica hypothetical protein 0.0048 0.02 1
Schistosoma mansoni tensin-related 0.0021 0.0011 0.0004
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0041 0.0153 0.0153
Echinococcus multilocularis tyrosine protein kinase Srms 0.0027 0.0052 0.0044
Brugia malayi hypothetical protein 0.0021 0.0011 0.0005
Echinococcus granulosus NCK adaptor protein 0.0041 0.0153 0.0145
Loa Loa (eye worm) cytochrome P450 family protein 0.0027 0.0054 0.0054
Echinococcus multilocularis NCK adaptor protein 0.0041 0.0153 0.0145
Schistosoma mansoni zinc finger protein 0.0073 0.0373 0.0371
Echinococcus multilocularis tyrosine protein kinase Blk 0.0027 0.0052 0.0044
Onchocerca volvulus 0.0027 0.0052 0.0331
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0024 0.0032 0.1262
Leishmania major hypothetical protein, conserved 0.0073 0.0373 1
Schistosoma mansoni signal transduction protein lnk-related 0.0021 0.0011 0.0004
Brugia malayi SH2 domain containing protein 0.0021 0.0011 0.0005
Onchocerca volvulus 0.0021 0.0011 0.0027
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0021 0.0011 0.0004
Echinococcus multilocularis SH2 motif 0.0021 0.0011 0.0004
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0073 0.0373 0.0475
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Echinococcus multilocularis leucine rich repeat serine:threonine protein 0.1124 0.7686 0.7684
Brugia malayi Sex muscle abnormal protein 5 0.0041 0.0153 0.0189
Trichomonas vaginalis hypothetical protein 0.0048 0.02 0.1498
Onchocerca volvulus 0.0021 0.0011 0.0027
Onchocerca volvulus 0.0073 0.0373 0.2722
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Schistosoma mansoni hypothetical protein 0.0205 0.129 0.1302
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0021 0.0011 0.0004
Schistosoma mansoni GTPase activating protein 0.0021 0.0011 0.0004
Brugia malayi cytokine inducible SH2-containing protein 5 0.0021 0.0011 0.0005
Echinococcus granulosus Nuclear pore complex protein Nup153 0.0073 0.0373 0.0365
Trypanosoma cruzi Zn-finger in Ran binding protein and others, putative 0.0073 0.0373 1
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0027 0.0052 0.0044
Echinococcus multilocularis Upstream activation factor subunit UAF30 0.0205 0.129 0.1284
Echinococcus granulosus rab protein 3 0.0048 0.02 0.0192
Echinococcus granulosus SH2 motif 0.0021 0.0011 0.0004
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0073 0.0373 0.0475
Echinococcus granulosus Upstream activation factor subunit UAF30 0.0205 0.129 0.1284
Echinococcus granulosus tensin C1 domain containing phosphatase 0.0021 0.0011 0.0004
Brugia malayi Variant SH3 domain containing protein 0.0041 0.0153 0.0189
Echinococcus multilocularis SWI:SNF matrix associated 0.0205 0.129 0.1284
Onchocerca volvulus 0.0021 0.0011 0.0027
Echinococcus multilocularis growth factor receptor bound protein 2 0.0041 0.0153 0.0145
Echinococcus multilocularis tumor protein p63 0.1456 0.9994 0.9994
Brugia malayi Cytochrome P450 family protein 0.0027 0.0054 0.006
Loa Loa (eye worm) SWIB/MDM2 domain-containing protein 0.0205 0.129 0.129
Schistosoma mansoni tyrosine kinase 0.0047 0.0194 0.0189
Schistosoma mansoni SH2A 0.0021 0.0011 0.0004
Loa Loa (eye worm) guanylate kinase 0.002 0.0008 0.0008
Brugia malayi STAT protein, DNA binding domain containing protein 0.0021 0.0011 0.0005
Loa Loa (eye worm) hypothetical protein 0.0021 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0073 0.0373 0.0373
Schistosoma mansoni adapter molecule crk 0.0041 0.0153 0.0147
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0027 0.0054 0.5
Schistosoma mansoni tyrosine kinase 0.1436 0.9855 1
Echinococcus multilocularis tyrosine protein kinase Abl 0.0594 0.3997 0.3993
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.0021 0.0011 0.0027
Onchocerca volvulus 0.0073 0.0373 0.2722
Loa Loa (eye worm) TK/FER protein kinase 0.0027 0.0052 0.0052
Trichomonas vaginalis GTP binding protein rare7l, putative 0.0048 0.02 0.1498
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Echinococcus granulosus c src tyrosine kinase 0.0047 0.0194 0.0186
Trypanosoma brucei mitochondrial RNA binding complex 1 subunit 0.0073 0.0373 1
Loa Loa (eye worm) hypothetical protein 0.0041 0.0153 0.0153
Trypanosoma cruzi WLM domain containing protein, putative 0.0073 0.0373 1
Trypanosoma cruzi WLM domain containing protein, putative 0.0073 0.0373 1
Trypanosoma cruzi mitochondrial RNA binding complex 1 subunit, putative 0.0073 0.0373 1
Schistosoma mansoni hypothetical protein 0.0205 0.129 0.1302
Brugia malayi Protein kinase domain containing protein 0.0027 0.0052 0.0058
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.0205 0.129 1
Echinococcus granulosus zinc finger protein Ran binding 0.0073 0.0373 0.0365
Schistosoma mansoni growth factor receptor-bound protein 0.0041 0.0153 0.0147
Brugia malayi SH2 domain containing protein 0.0027 0.0052 0.0058
Onchocerca volvulus 0.0021 0.0011 0.0027
Schistosoma mansoni serine/threonine protein kinase 0.0026 0.0049 0.0041
Brugia malayi brahma associated protein 60 kDa 0.0205 0.129 0.167

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.