Detailed information for compound 1615496

Basic information

Technical information
  • TDR Targets ID: 1615496
  • Name: 1,3-di(propan-2-yl)-4,5-dihydroimidazol-1-ium tetrafluoroborate
  • MW: 242.065 | Formula: C9H19BF4N2
  • H donors: 0 H acceptors: 0 LogP: 3.6 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: F[B-](F)(F)F.CC(N1CC[N+](=C1)C(C)C)C
  • InChi: 1S/C9H19N2.BF4/c1-8(2)10-5-6-11(7-10)9(3)4;2-1(3,4)5/h7-9H,5-6H2,1-4H3;/q+1;-1
  • InChiKey: MRUAIISBFNRJSL-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 1,3-diisopropyl-4,5-dihydroimidazol-1-ium tetrafluoroborate
  • 660000_ALDRICH
  • N,N′-Diisopropyldihydroimidazolium tetrafluoroborate
  • 1,3-Diisopropyl-4,5-dihydro-3H-imidazol-1-ium
  • AIDS-158222
  • AIDS158222
  • NSC664858
  • 1,3-Diisopropylimidazolinium tetrafluoroborate
  • 4,5-Dihydro-1,3-bis(1-methylethyl)-1H-imidazolium tetrafluoroborate

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.002 0.0009 0.0042
Echinococcus multilocularis potassium voltage gated channel protein 0.0315 0.0628 0.0623
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0035 0.004 0.0532
Echinococcus multilocularis transient receptor potential gamma protein 0.0315 0.0628 0.0623
Loa Loa (eye worm) hypothetical protein 0.0315 0.0628 0.1459
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0026 0.0021 0.4189
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0048 0.0068 0.0986
Schistosoma mansoni peroxidasin 0.2046 0.427 1
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0165 0.0314 0.0308
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0315 0.0628 0.1347
Onchocerca volvulus 0.0366 0.0737 0.1606
Loa Loa (eye worm) hypothetical protein 0.0315 0.0628 0.1459
Schistosoma mansoni hypothetical protein 0.004 0.005 0.0103
Schistosoma mansoni patched 1 0.0041 0.0053 0.0111
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0315 0.0628 0.1472
Brugia malayi notch-like transmembrane receptor 0.0366 0.0737 0.1727
Loa Loa (eye worm) hypothetical protein 0.0315 0.0628 0.1459
Echinococcus granulosus delta-like protein 1 0.0366 0.0737 0.0732
Schistosoma mansoni ryanodine receptor related 0.0315 0.0628 0.1459
Leishmania major importin beta-1 subunit, putative 0.0026 0.0022 0.0016
Schistosoma mansoni voltage-gated potassium channel 0.0315 0.0628 0.1459
Loa Loa (eye worm) hypothetical protein 0.0315 0.0628 0.1459
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0062 0.0097 0.0228
Loa Loa (eye worm) large conductance calcium-activated potassium channel alpha subunit ai 0.0087 0.015 0.0336
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.002 0.0009 0.0041
Echinococcus multilocularis transfer RNA-Gly 0.0315 0.0628 0.0623
Schistosoma mansoni peripheral-type benzodiazepine receptor 0.1731 0.3609 0.8449
Echinococcus granulosus tar DNA binding protein 0.0102 0.0181 0.0175
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0069 0.0112 0.0106
Loa Loa (eye worm) hypothetical protein 0.0315 0.0628 0.1459
Brugia malayi Animal haem peroxidase family protein 0.2046 0.427 1
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0319 0.0637 0.1491
Echinococcus multilocularis neural cadherin 0.0366 0.0737 0.0732
Echinococcus granulosus short transient receptor potential channel 6 0.0315 0.0628 0.0623
Onchocerca volvulus 0.0366 0.0737 0.1606
Schistosoma mansoni voltage-gated potassium channel 0.0315 0.0628 0.1459
Trichomonas vaginalis inositol monophosphatase, putative 0.0035 0.004 0.0532
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0315 0.0628 0.0623
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0319 0.0637 0.1479
Brugia malayi N-terminal motif family protein 0.0181 0.0347 0.0812
Loa Loa (eye worm) MaxiK calcium-activated potassium channel 0.0062 0.0097 0.0214
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0335 0.0671 0.6843
Onchocerca volvulus Peroxidase homolog 0.2046 0.427 1
Echinococcus multilocularis protein jagged 1 0.0366 0.0737 0.0732
Brugia malayi TAR-binding protein 0.0102 0.0181 0.0425
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0068 0.0146
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0045 0.0062 0.0154
Loa Loa (eye worm) hypothetical protein 0.0315 0.0628 0.1459
Onchocerca volvulus 0.1731 0.3609 0.8429
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0315 0.0628 1
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0045 0.0062 1
Schistosoma mansoni hypothetical protein 0.0061 0.0095 0.0207
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0035 0.004 0.0539
Schistosoma mansoni septate junction protein 0.0366 0.0737 0.1715
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.002 0.0009 0.0006
Schistosoma mansoni transient receptor potential channel 0.0315 0.0628 0.1459
Echinococcus granulosus neurogenic locus notch protein 0.0366 0.0737 0.0732
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.002 0.0009 0.0042
Echinococcus multilocularis mitogen activated protein kinase 3 0.0048 0.0068 0.0061
Echinococcus multilocularis fat cadherin tumor suppressor 0.0366 0.0737 0.0732
Onchocerca volvulus Putative cubilin 0.0366 0.0737 0.1606
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0009 0.0042
Schistosoma mansoni hypothetical protein 0.0366 0.0737 0.1715
Echinococcus granulosus transient receptor potential cation channel 0.0315 0.0628 0.0623
Onchocerca volvulus Neurogenic locus notch homolog 0.0366 0.0737 0.1606
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0006
Echinococcus granulosus TRP transient receptor potential channel 0.0315 0.0628 0.0623
Echinococcus granulosus potassium large conductance calcium activated 0.0402 0.0812 0.0806
Echinococcus multilocularis voltage dependent calcium channel 0.0315 0.0628 0.0623
Trypanosoma brucei importin beta-1 subunit, putative 0.0033 0.0035 0.0466
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0048 0.0068 0.0144
Onchocerca volvulus Chorion peroxidase homolog 0.2046 0.427 1
Echinococcus granulosus transient receptor potential cation channel 0.0315 0.0628 0.0623
Loa Loa (eye worm) hypothetical protein 0.2046 0.427 1
Plasmodium falciparum acyl-CoA synthetase 0.0034 0.0038 1
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0315 0.0628 0.1472
Echinococcus granulosus Protein patched homolog 1 0.0041 0.0053 0.0047
Echinococcus granulosus slit 2 protein 0.0366 0.0737 0.0732
Schistosoma mansoni tar DNA-binding protein 0.0102 0.0181 0.0411
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0315 0.0628 0.1459
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0024 0.0017 0.2871
Leishmania major hypothetical protein, conserved 0.0026 0.0021 0.0015
Schistosoma mansoni hypothetical protein 0.0366 0.0737 0.1715
Toxoplasma gondii transporter, cation channel family protein 0.0315 0.0628 0.6405
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.002 0.0009 0.0041
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.002 0.0009 0.0021
Brugia malayi MAP kinase sur-1 0.0048 0.0068 0.0158
Schistosoma mansoni tar DNA-binding protein 0.0102 0.0181 0.0411
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.002 0.0009 0.0041
Brugia malayi AMP-binding enzyme family protein 0.0045 0.0062 0.0144
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0006 0.0015
Loa Loa (eye worm) hypothetical protein 0.1731 0.3609 0.8449
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.002 0.0009 0.0021
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0315 0.0628 0.1472
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0319 0.0637 0.0631
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.002 0.0009 0.0041
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0018 0.3325
Loa Loa (eye worm) hypothetical protein 0.2046 0.427 1
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0009 0.0041
Schistosoma mansoni hypothetical protein 0.004 0.005 0.0103
Echinococcus multilocularis protein dispatched 1 0.0047 0.0066 0.006
Schistosoma mansoni voltage-gated potassium channel 0.0315 0.0628 0.1459
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.002 0.0009 0.0041
Loa Loa (eye worm) hypothetical protein 0.0045 0.0062 0.013
Onchocerca volvulus 0.2046 0.427 1
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.002 0.0009 0.0041
Plasmodium vivax potassium channel, putative 0.0025 0.0019 0.3484
Loa Loa (eye worm) hypothetical protein 0.2046 0.427 1
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0026 0.0021 0.0235
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0319 0.0637 1
Loa Loa (eye worm) hypothetical protein 0.0366 0.0737 0.1715
Schistosoma mansoni voltage-gated ion channel 0.0315 0.0628 0.1459
Schistosoma mansoni ran 0.0024 0.0017 0.0025
Onchocerca volvulus 0.0366 0.0737 0.1606
Loa Loa (eye worm) hypothetical protein 0.0315 0.0628 0.1459
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0035 0.004 0.0539
Loa Loa (eye worm) hypothetical protein 0.0366 0.0737 0.1715
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0319 0.0637 0.0631
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0319 0.0637 0.1479
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0145 0.0272 0.0266
Schistosoma mansoni hypothetical protein 0.0045 0.0062 0.0131
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0315 0.0628 0.0623
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0098 0.0172 0.039
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0024 0.0017 0.0085
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0041 0.0053 0.0124
Loa Loa (eye worm) hypothetical protein 0.2046 0.427 1
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.002 0.0009 0.0041
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0053 0.075
Echinococcus multilocularis neurogenic locus notch protein 4 0.0366 0.0737 0.0732
Echinococcus multilocularis calcium activated potassium channel 0.0402 0.0813 0.0807
Brugia malayi CHE-14 protein 0.0041 0.0053 0.0125
Echinococcus granulosus protein jagged 1 0.0366 0.0737 0.0732
Echinococcus multilocularis slit 2 protein 0.0366 0.0737 0.0732
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0024 0.0017 0.0149
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.002 0.0009 0.0041
Echinococcus granulosus peroxidasin 0.2046 0.427 0.4267
Schistosoma mansoni serine/threonine protein kinase 0.0048 0.0068 0.0144
Mycobacterium ulcerans tryptophan-rich sensory protein 0.1731 0.3609 1
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.002 0.0009 0.0042
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0315 0.0628 0.1459
Loa Loa (eye worm) notch protein 0.0366 0.0737 0.1715
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0319 0.0637 0.0631
Loa Loa (eye worm) hypothetical protein 0.0366 0.0737 0.1715
Onchocerca volvulus 0.2046 0.427 1
Loa Loa (eye worm) hypothetical protein 0.0041 0.0053 0.0111
Brugia malayi Calcium binding EGF domain containing protein 0.0366 0.0737 0.1727
Loa Loa (eye worm) hypothetical protein 0.0366 0.0737 0.1715
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.002 0.0009 0.0042
Loa Loa (eye worm) hypothetical protein 0.0025 0.0019 0.003
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0319 0.0637 0.0631
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.002 0.0009 0.0003
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0366 0.0737 0.1727
Schistosoma mansoni survival motor neuron protein 0.0045 0.0062 0.0131
Echinococcus multilocularis GPCR, family 2 0.0061 0.0095 0.0088
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0035 0.004 0.5
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0009 0.0042
Echinococcus multilocularis two pore calcium channel protein 1 0.0315 0.0628 0.0623
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0061 0.0095 0.0088
Schistosoma mansoni transient receptor potential channel 0.0315 0.0628 0.1459
Brugia malayi Inositol-1 0.0035 0.004 0.0093
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0045 0.0062 1
Schistosoma mansoni hypothetical protein 0.0315 0.0628 0.1459
Echinococcus granulosus mitogen activated protein kinase 3 0.0048 0.0068 0.0061
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0045 0.0062 0.0146
Brugia malayi EGF-like domain containing protein 0.0366 0.0737 0.1727
Brugia malayi hypothetical protein 0.0223 0.0436 0.102
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0315 0.0628 0.1459
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.002 0.0009 0.0042
Loa Loa (eye worm) RNA binding protein 0.0102 0.0181 0.0411
Entamoeba histolytica acyl-coA synthetase, putative 0.0045 0.0062 0.3401
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0192 0.0371 0.0869
Leishmania major hypothetical protein, conserved 0.002 0.0009 0.0003
Leishmania major GTP-binding protein, putative 0.0024 0.0017 0.0011
Echinococcus granulosus neurogenic locus notch protein 4 0.0366 0.0737 0.0732
Loa Loa (eye worm) hypothetical protein 0.0045 0.0062 0.013
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.002 0.0009 0.0041
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0024 0.0017 0.0011
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0045 0.0062 1
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0006 0.0015
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0315 0.0628 0.1459
Echinococcus multilocularis tumor protein p63 0.0331 0.0662 0.0656
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.002 0.0009 0.0006
Echinococcus multilocularis neurogenic locus protein delta 0.0366 0.0737 0.0732
Schistosoma mansoni hypothetical protein 0.004 0.005 0.0103
Echinococcus multilocularis expressed conserved protein 0.0091 0.0157 0.0151
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.002 0.0009 0.0003
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.002 0.0009 0.0041
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0009 0.0041
Schistosoma mansoni peroxidasin 0.2046 0.427 1
Loa Loa (eye worm) hypothetical protein 0.0315 0.0628 0.1459
Echinococcus multilocularis transient receptor potential cation channel 0.0315 0.0628 0.0623
Echinococcus multilocularis two pore calcium channel protein 2 0.0315 0.0628 0.0623
Echinococcus multilocularis transient receptor potential cation channel 0.0315 0.0628 0.0623
Mycobacterium ulcerans acyl-CoA synthetase 0.0045 0.0062 0.0154
Echinococcus multilocularis transient receptor potential cation channel 0.0315 0.0628 0.0623
Echinococcus granulosus transient receptor potential cation channel 0.0315 0.0628 0.0623
Loa Loa (eye worm) hypothetical protein 0.0315 0.0628 0.1459
Leishmania major hypothetical protein, conserved 0.002 0.0009 0.0003
Brugia malayi hypothetical protein 0.2046 0.427 1
Brugia malayi MH2 domain containing protein 0.0117 0.0212 0.0497
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0026 0.0021 0.0235
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0315 0.0628 0.1459
Loa Loa (eye worm) ion channel NompC 0.0315 0.0628 0.1459
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.002 0.0009 0.0042
Echinococcus granulosus transient receptor potential cation channel 0.0315 0.0628 0.0623
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0319 0.0637 0.0631
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0024 0.0017 0.0175
Loa Loa (eye worm) hypothetical protein 0.2046 0.427 1
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0315 0.0628 0.0623
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0315 0.0628 0.1472
Echinococcus granulosus calcium activated potassium channel variant 0.0087 0.015 0.0144
Echinococcus multilocularis protein jagged 1 0.0366 0.0737 0.0732
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0061 0.0095 0.0088
Echinococcus multilocularis translocator protein 0.1731 0.3609 0.3605
Brugia malayi hypothetical protein 0.0069 0.0112 0.0262
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0315 0.0628 0.0623
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0006
Echinococcus granulosus sodium leak channel non selective protein 0.0315 0.0628 0.0623
Trichomonas vaginalis CMGC family protein kinase 0.0048 0.0068 0.0973
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.002 0.0009 0.0041
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0315 0.0628 0.0623
Brugia malayi Augmenter of liver regeneration 0.0026 0.0021 0.0049
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.002 0.0009 0.0021
Echinococcus multilocularis transient receptor potential cation channel 0.0315 0.0628 0.0623
Echinococcus granulosus GTP binding nuclear protein Ran 0.0024 0.0017 0.0011
Schistosoma mansoni slit 0.0366 0.0737 0.1715
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0315 0.0628 0.0623
Brugia malayi Animal haem peroxidase family protein 0.2046 0.427 1
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0022 0.0254
Echinococcus multilocularis sterol regulatory element binding protein 0.0041 0.0053 0.0047
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0319 0.0637 0.1479
Toxoplasma gondii transporter, cation channel family protein 0.0315 0.0628 0.6405
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0018 0.0195
Echinococcus granulosus transient receptor potential cation channel 0.0315 0.0628 0.0623
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0034 0.0038 0.5
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.002 0.0009 0.0041
Echinococcus granulosus neural cadherin 0.0366 0.0737 0.0732
Echinococcus multilocularis peroxidasin 0.2046 0.427 0.4267
Onchocerca volvulus Dual oxidase homolog 0.2046 0.427 1
Brugia malayi Importin beta-1 subunit 0.0033 0.0035 0.0083
Trichomonas vaginalis CMGC family protein kinase 0.0048 0.0068 0.0973
Schistosoma mansoni notch 0.0366 0.0737 0.1715
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0045 0.0062 1
Schistosoma mansoni cell polarity protein 0.0366 0.0737 0.1715
Brugia malayi Animal haem peroxidase family protein 0.2046 0.427 1
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.002 0.0009 0.0003
Schistosoma mansoni inositol monophosphatase 0.0035 0.004 0.0079
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0026 0.0021 0.0235
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0315 0.0628 0.0623
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0315 0.0628 0.0623
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.002 0.0009 0.0041
Toxoplasma gondii Erv1 / Alr family protein 0.0026 0.0021 0.0125
Loa Loa (eye worm) hypothetical protein 0.0051 0.0073 0.0157
Brugia malayi EGF-like domain containing protein 0.0366 0.0737 0.1727
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0035 0.004 0.032
Echinococcus granulosus transient receptor potential cation channel 0.0315 0.0628 0.0623
Onchocerca volvulus 0.1731 0.3609 0.8429
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0024 0.0017 0.0175
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0315 0.0628 0.1459
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0349 0.07 0.1628
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0319 0.0637 0.0631
Loa Loa (eye worm) hypothetical protein 0.0366 0.0737 0.1715
Schistosoma mansoni inositol monophosphatase 0.0035 0.004 0.0079
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.002 0.0009 0.0003
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.002 0.0009 0.0041
Brugia malayi hypothetical protein 0.0025 0.0018 0.0043
Brugia malayi Muscle positioning protein 4 0.0366 0.0737 0.1727
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0315 0.0628 0.1459
Schistosoma mansoni voltage-gated potassium channel 0.0315 0.0628 0.1459
Onchocerca volvulus Peroxidase homolog 0.2046 0.427 1
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0026 0.0021 0.0235
Brugia malayi TspO/MBR family protein 0.1731 0.3609 0.8451
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0024 0.0017 0.2871
Loa Loa (eye worm) hypothetical protein 0.0061 0.0095 0.0207
Echinococcus granulosus ryanodine receptor 44f 0.0315 0.0628 0.0623
Loa Loa (eye worm) hypothetical protein 0.0045 0.0062 0.013
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.002 0.0009 0.0041
Echinococcus multilocularis potassium voltage gated channel protein 0.0315 0.0628 0.0623
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.002 0.0009 0.0041
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0032 0.0034 0.4959
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.002 0.0009 0.0003
Echinococcus granulosus fibropellin Ia 0.0366 0.0737 0.0732
Onchocerca volvulus 0.2046 0.427 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.0018 0.0029
Echinococcus multilocularis neurogenic locus notch protein 0.0366 0.0737 0.0732
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.002 0.0009 0.0041
Echinococcus granulosus GPCR family 2 0.0061 0.0095 0.0088
Loa Loa (eye worm) hypothetical protein 0.2046 0.427 1
Loa Loa (eye worm) hypothetical protein 0.0319 0.0637 0.1479
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0096 0.0169 1
Schistosoma mansoni notch 0.0366 0.0737 0.1715
Loa Loa (eye worm) voltage-dependent calcium channel 0.0315 0.0628 0.1459
Echinococcus multilocularis neurogenic locus protein delta 0.0366 0.0737 0.0732
Loa Loa (eye worm) hypothetical protein 0.2046 0.427 1
Echinococcus granulosus voltage gated potassium channel 0.0315 0.0628 0.0623
Entamoeba histolytica hypothetical protein 0.0069 0.0112 0.6486
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.002 0.0009 0.0041
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.002 0.0009 0.0041
Brugia malayi olfactory channel protein osm-9 0.0315 0.0628 0.1472
Loa Loa (eye worm) hypothetical protein 0.0366 0.0737 0.1715
Onchocerca volvulus 0.0048 0.0068 0.0016
Brugia malayi ion channel NompC 0.0315 0.0628 0.1472
Mycobacterium ulcerans acyl-CoA synthetase 0.0045 0.0062 0.0154
Brugia malayi Calcitonin receptor-like protein seb-1 0.0192 0.0371 0.0869
Echinococcus multilocularis hyperpolarization activated cyclic 0.0319 0.0637 0.0631
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0165 0.0314 0.0308
Schistosoma mansoni hypothetical protein 0.0476 0.0969 0.2257
Leishmania major 4-coumarate:coa ligase-like protein 0.0045 0.0062 0.0055
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0018 0.0099
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0034 0.0038 0.0087
Loa Loa (eye worm) hypothetical protein 0.2046 0.427 1
Echinococcus multilocularis notch 0.0366 0.0737 0.0732
Loa Loa (eye worm) TAR-binding protein 0.0102 0.0181 0.0411
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0024 0.0017 0.0175
Echinococcus multilocularis Niemann Pick C1 protein 0.0138 0.0256 0.025
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0315 0.0628 1
Entamoeba histolytica Ran family GTPase 0.0024 0.0017 0.0666
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0041 0.0053 0.0047
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0165 0.0314 0.4213
Schistosoma mansoni microsomal glutathione s-transferase 0.0045 0.0062 0.013
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0061 0.0095 0.0221
Brugia malayi latrophilin 2 splice variant baaae 0.0132 0.0243 0.0569
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0315 0.0628 0.0623
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.002 0.0009 0.0041
Loa Loa (eye worm) latrophilin receptor protein 2 0.0061 0.0095 0.0207
Onchocerca volvulus 0.0366 0.0737 0.1606
Leishmania major hypothetical protein, conserved 0.0315 0.0628 0.0623
Loa Loa (eye worm) ryanodine receptor 0.0315 0.0628 0.1459
Plasmodium vivax importin-beta 2, putative 0.0033 0.0035 0.9177
Echinococcus granulosus protein jagged 2 0.0366 0.0737 0.0732
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.002 0.0009 0.0006
Echinococcus granulosus translocator protein 0.1731 0.3609 0.3605
Loa Loa (eye worm) hypothetical protein 0.0132 0.0243 0.0556
Toxoplasma gondii EGF family domain-containing protein 0.0366 0.0737 0.753
Schistosoma mansoni hypothetical protein 0.0132 0.0243 0.0556
Brugia malayi AMP-binding enzyme family protein 0.0045 0.0062 0.0144
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.002 0.0009 0.0041
Loa Loa (eye worm) hypothetical protein 0.2046 0.427 1
Onchocerca volvulus 0.1731 0.3609 0.8429
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.002 0.0009 0.0041
Echinococcus multilocularis importin subunit beta 1 0.0033 0.0035 0.0029
Schistosoma mansoni hypothetical protein 0.0366 0.0737 0.1715
Echinococcus granulosus potassium voltage gated channel protein 0.0315 0.0628 0.0623
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0061 0.0095 0.0088
Schistosoma mansoni voltage-gated potassium channel 0.0315 0.0628 0.1459
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0048 0.0068 0.0986
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.002 0.0009 0.0021
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.002 0.0009 0.0021
Loa Loa (eye worm) hypothetical protein 0.0315 0.0628 0.1459
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0315 0.0628 0.1472
Loa Loa (eye worm) hypothetical protein 0.1731 0.3609 0.8449
Loa Loa (eye worm) hypothetical protein 0.0315 0.0628 0.1459
Loa Loa (eye worm) hypothetical protein 0.2046 0.427 1
Echinococcus granulosus potassium voltage gated channel protein 0.0315 0.0628 0.0623
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0041 0.0053 0.0109
Echinococcus multilocularis hyperpolarization activated cyclic 0.0319 0.0637 0.0631
Loa Loa (eye worm) hypothetical protein 0.0315 0.0628 0.1459
Echinococcus multilocularis short transient receptor potential channel 6 0.0315 0.0628 0.0623
Toxoplasma gondii hypothetical protein 0.0315 0.0628 0.6405
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.048 0.0976 1
Echinococcus granulosus sterol regulatory element binding protein 0.0041 0.0053 0.0047
Brugia malayi Cadherin domain containing protein 0.0366 0.0737 0.1727
Echinococcus multilocularis transient receptor potential cation channel 0.0315 0.0628 0.0623
Loa Loa (eye worm) Notch2 0.0366 0.0737 0.1715
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0045 0.0062 0.0154
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.002 0.0009 0.0041
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0315 0.0628 0.1459
Echinococcus granulosus mitogen activated protein kinase 0.0048 0.0068 0.0061
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0041 0.0053 0.0047
Loa Loa (eye worm) hypothetical protein 0.0315 0.0628 0.1459
Schistosoma mansoni tar DNA-binding protein 0.0102 0.0181 0.0411
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.002 0.0009 0.0042
Loa Loa (eye worm) hypothetical protein 0.0366 0.0737 0.1715
Giardia lamblia hypothetical protein 0.002 0.0009 0.0035
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.002 0.0009 0.0042
Loa Loa (eye worm) hypothetical protein 0.0165 0.0314 0.0722
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0048 0.0068 0.0986
Echinococcus granulosus notch 0.0366 0.0737 0.0732
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.002 0.0009 0.0003
Brugia malayi Animal haem peroxidase family protein 0.2046 0.427 1
Echinococcus multilocularis transient receptor potential cation channel 0.0315 0.0628 0.0623
Brugia malayi Latrophilin receptor protein 2 0.0061 0.0095 0.0221
Schistosoma mansoni voltage-gated potassium channel 0.0319 0.0637 0.1479
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.002 0.0009 0.0041
Echinococcus granulosus hyperpolarization activated cyclic 0.0319 0.0637 0.0631
Onchocerca volvulus Peroxidasin homolog 0.2046 0.427 1
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0315 0.0628 1
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A 0.0145 0.0272 0.0623
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0315 0.0628 0.0623
Schistosoma mansoni voltage-gated potassium channel 0.0315 0.0628 0.1459
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0315 0.0628 0.1472
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0315 0.0628 0.1459
Toxoplasma gondii ion channel protein 0.0025 0.0019 0.0104
Trypanosoma brucei cAMP-specific phosphodiesterase 0.002 0.0009 0.0042
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0041 0.0053 0.0109
Echinococcus multilocularis voltage dependent calcium channel 0.0315 0.0628 0.0623
Schistosoma mansoni laminin gamma-3 chain 0.0366 0.0737 0.1715
Echinococcus multilocularis geminin 0.0476 0.0969 0.0963
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0035 0.004 0.0093
Loa Loa (eye worm) hypothetical protein 0.2046 0.427 1
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.002 0.0009 0.0006
Schistosoma mansoni transient receptor potential channel 0.0315 0.0628 0.1459
Loa Loa (eye worm) hypothetical protein 0.0062 0.0097 0.0214
Echinococcus granulosus voltage gated hydrogen channel 1 0.0315 0.0628 0.0623
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0048 0.0068 0.0986
Schistosoma mansoni voltage-dependent calcium channel 0.0315 0.0628 0.1459
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0181 0.0347 0.0678
Echinococcus multilocularis inositol monophosphatase 1 0.0035 0.004 0.0034
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.002 0.0009 0.0041
Giardia lamblia Hypothetical protein 0.002 0.0009 0.0035
Entamoeba histolytica acyl-CoA synthetase, putative 0.0045 0.0062 0.3401
Brugia malayi Blistered cuticle protein 3 0.2046 0.427 1
Brugia malayi EGF-like domain containing protein 0.0366 0.0737 0.1727
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0315 0.0628 0.0623
Loa Loa (eye worm) voltage-gated potassium channel 0.0315 0.0628 0.1459
Loa Loa (eye worm) hypothetical protein 0.0034 0.0038 0.0074
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0048 0.0068 0.0986
Loa Loa (eye worm) hypothetical protein 0.0366 0.0737 0.1715
Loa Loa (eye worm) hypothetical protein 0.0192 0.0371 0.0856
Loa Loa (eye worm) hypothetical protein 0.1731 0.3609 0.8449
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0032 0.0034 0.4959
Brugia malayi Transient-receptor-potential like protein 0.0315 0.0628 0.1472
Echinococcus multilocularis voltage gated potassium channel 0.0315 0.0628 0.0623
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.002 0.0009 0.0006
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0315 0.0628 0.0623
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.002 0.0009 0.0003
Loa Loa (eye worm) hypothetical protein 0.0366 0.0737 0.1715
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0315 0.0628 0.1347
Loa Loa (eye worm) hypothetical protein 0.0366 0.0737 0.1715
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0069 0.0112 0.0106
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.002 0.0009 0.0003
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0315 0.0628 0.0623
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0319 0.0637 0.0631
Schistosoma mansoni ran 0.0024 0.0017 0.0025
Brugia malayi Calcium binding EGF domain containing protein 0.0366 0.0737 0.1727
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.002 0.0009 0.0003
Loa Loa (eye worm) hypothetical protein 0.0315 0.0628 0.1459
Echinococcus multilocularis ryanodine receptor 44f 0.0315 0.0628 0.0623
Loa Loa (eye worm) hypothetical protein 0.0315 0.0628 0.1459
Loa Loa (eye worm) hypothetical protein 0.2046 0.427 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0045 0.0062 0.0154
Trypanosoma cruzi importin beta-1 subunit, putative 0.0026 0.0022 0.0257
Echinococcus granulosus voltage dependent calcium channel 0.0315 0.0628 0.0623
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0034 0.0038 0.566
Schistosoma mansoni voltage-gated potassium channel 0.0315 0.0628 0.1459
Trypanosoma cruzi calcium/potassium channel (CAKC), putative 0.0025 0.0019 0.0203
Brugia malayi Cadherin domain containing protein 0.0366 0.0737 0.1727
Echinococcus granulosus hyperpolarization activated cyclic 0.0319 0.0637 0.0631
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.002 0.0009 0.0041
Schistosoma mansoni membrane associated proteins in eicosanoid and glutathione metabolism family member 0.0197 0.0382 0.0881
Leishmania major hypothetical protein, conserved 0.0025 0.0018 0.0012
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0319 0.0637 0.1479
Trypanosoma cruzi calcium/potassium channel (CAKC), putative 0.0025 0.0019 0.0203
Echinococcus granulosus neurogenic locus notch protein 0.0366 0.0737 0.0732
Brugia malayi hypothetical protein 0.0699 0.1437 0.3365
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.002 0.0009 0.0041
Loa Loa (eye worm) hypothetical protein 0.1731 0.3609 0.8449
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0018 0.3325
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0315 0.0628 0.1459
Schistosoma mansoni 60S ribosomal protein L21 0.0315 0.0628 0.1459
Leishmania major 4-coumarate:coa ligase-like protein 0.0045 0.0062 0.0055
Echinococcus granulosus snurportin 1 0.0349 0.07 0.0695
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0045 0.0062 0.0154
Mycobacterium ulcerans hypothetical protein 0.0045 0.0062 0.0154
Brugia malayi Animal haem peroxidase family protein 0.2046 0.427 1
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0315 0.0628 0.0623
Echinococcus granulosus potassium voltage gated channel protein 0.0315 0.0628 0.0623
Loa Loa (eye worm) hypothetical protein 0.0366 0.0737 0.1715
Echinococcus granulosus calcium activated potassium channel 0.0402 0.0813 0.0807
Echinococcus granulosus short transient receptor potential channel 6 0.0315 0.0628 0.0623
Echinococcus granulosus importin subunit beta 1 0.0033 0.0035 0.0029
Brugia malayi Delta serrate ligand family protein 0.0366 0.0737 0.1727
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.002 0.0009 0.0003
Echinococcus multilocularis Niemann Pick C1 protein 0.0096 0.0169 0.0163
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0009 0.0042
Loa Loa (eye worm) hypothetical protein 0.0033 0.0035 0.0068
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0319 0.0637 1
Giardia lamblia Kinase, CMGC MAPK 0.0048 0.0068 0.0839
Schistosoma mansoni transcription factor LCR-F1 0.0069 0.0112 0.0248
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.002 0.0009 0.0042
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0035 0.004 0.0539
Loa Loa (eye worm) hypothetical protein 0.0366 0.0737 0.1715
Trypanosoma brucei importin beta-1 subunit, putative 0.0033 0.0035 0.0466
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0192 0.0371 0.0856
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0319 0.0637 0.1479
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0145 0.0272 0.0637
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0035 0.004 0.2057
Echinococcus granulosus survival motor neuron protein 1 0.0223 0.0436 0.043
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.002 0.0009 0.0041
Loa Loa (eye worm) hypothetical protein 0.0319 0.0637 0.1479
Plasmodium vivax acyl-CoA synthetase, putative 0.0034 0.0038 1
Trichomonas vaginalis CMGC family protein kinase 0.0048 0.0068 0.0973
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0315 0.0628 0.1472
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0026 0.0021 0.4189
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.002 0.0009 0.0041
Brugia malayi Niemann-Pick C1 protein precursor 0.0096 0.0169 0.0396
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0315 0.0628 0.0623
Loa Loa (eye worm) hypothetical protein 0.0096 0.0169 0.0382
Loa Loa (eye worm) hypothetical protein 0.0315 0.0628 0.1459
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0319 0.0637 0.1491
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0315 0.0628 0.1459
Toxoplasma gondii HEAT repeat-containing protein 0.0033 0.0035 0.0273
Echinococcus multilocularis mitogen activated protein kinase 0.0048 0.0068 0.0061
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.002 0.0009 0.0042
Giardia lamblia High cysteine protein 0.0366 0.0737 1
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0319 0.0637 0.0631
Loa Loa (eye worm) hypothetical protein 0.0034 0.0038 0.0074
Trypanosoma brucei cAMP-specific phosphodiesterase 0.002 0.0009 0.0042
Loa Loa (eye worm) animal heme peroxidase 0.2046 0.427 1
Echinococcus multilocularis voltage gated potassium channel 0.0319 0.0637 0.0631
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0024 0.0017 0.004
Echinococcus granulosus neurogenic locus protein delta 0.0366 0.0737 0.0732
Entamoeba histolytica hypothetical protein 0.0069 0.0112 0.6486
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0045 0.0062 0.0154
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.002 0.0009 0.0006
Echinococcus multilocularis protein jagged 2 0.0366 0.0737 0.0732
Toxoplasma gondii transporter, cation channel family protein 0.0315 0.0628 0.6405
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0041 0.0053 0.0047
Schistosoma mansoni voltage-gated potassium channel 0.0319 0.0637 0.1479
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0366 0.0737 0.1606
Schistosoma mansoni tar DNA-binding protein 0.0102 0.0181 0.0411
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0319 0.0637 0.1479
Onchocerca volvulus 0.0045 0.0062 0.0001
Echinococcus multilocularis tar DNA binding protein 0.0102 0.0181 0.0175
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.002 0.0009 0.0041
Loa Loa (eye worm) hypothetical protein 0.0315 0.0628 0.1459
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0041 0.0053 0.0109
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0024 0.0017 0.0025
Schistosoma mansoni voltage-gated potassium channel 0.0315 0.0628 0.1459
Schistosoma mansoni voltage-gated potassium channel 0.0319 0.0637 0.1479
Schistosoma mansoni voltage-gated potassium channel 0.0315 0.0628 0.1459
Loa Loa (eye worm) hypothetical protein 0.0366 0.0737 0.1715
Echinococcus multilocularis potassium large conductance calcium activated 0.0402 0.0812 0.0806
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0041 0.0053 0.0111
Brugia malayi Peroxidasin 0.2046 0.427 1
Schistosoma mansoni hypothetical protein 0.004 0.005 0.0103
Loa Loa (eye worm) MH2 domain-containing protein 0.0117 0.0212 0.0483
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0009 0.0042
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0026 0.0021 0.0015
Schistosoma mansoni hypothetical protein 0.0069 0.0112 0.0248
Entamoeba histolytica acyl-CoA synthetase, putative 0.0045 0.0062 0.3401
Trypanosoma brucei hypothetical protein, conserved 0.002 0.0009 0.0042
Trypanosoma brucei calcium/potassium channel (CAKC), putative 0.0025 0.0019 0.0203
Schistosoma mansoni hypothetical protein 0.0366 0.0737 0.1715
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.002 0.0009 0.0041
Trichomonas vaginalis ran, putative 0.0024 0.0017 0.0172
Brugia malayi RNA, U transporter 1 0.0093 0.0162 0.0379
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0315 0.0628 0.0623
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0165 0.0314 0.0308
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1548 0.3222 0.3218
Loa Loa (eye worm) hypothetical protein 0.0366 0.0737 0.1715
Echinococcus granulosus geminin 0.0476 0.0969 0.0963
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0009 0.0041
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0018 0.0195
Loa Loa (eye worm) animal heme peroxidase 0.2046 0.427 1
Loa Loa (eye worm) hypothetical protein 0.0366 0.0737 0.1715
Schistosoma mansoni voltage-gated potassium channel 0.0319 0.0637 0.1479
Schistosoma mansoni transient receptor potential channel 4 0.0315 0.0628 0.1459
Schistosoma mansoni notch 0.0366 0.0737 0.1715
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0165 0.0314 0.0722
Toxoplasma gondii ion channel protein 0.0025 0.0019 0.0104
Echinococcus multilocularis protein patched 0.0041 0.0053 0.0047
Loa Loa (eye worm) hypothetical protein 0.0034 0.0038 0.0074
Schistosoma mansoni voltage-gated potassium channel 0.0315 0.0628 0.1459
Schistosoma mansoni notch 0.0366 0.0737 0.1715
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.002 0.0009 0.0003
Loa Loa (eye worm) hypothetical protein 0.2046 0.427 1
Echinococcus multilocularis fibropellin Ia 0.0366 0.0737 0.0732
Schistosoma mansoni voltage-gated potassium channel 0.0315 0.0628 0.1459
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.002 0.0009 0.0006
Echinococcus granulosus Niemann Pick C1 protein 0.0096 0.0169 0.0163
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0315 0.0628 0.1472
Loa Loa (eye worm) hypothetical protein 0.0034 0.0038 0.0074
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0315 0.0628 0.0623
Schistosoma mansoni hypothetical protein 0.0366 0.0737 0.1715
Plasmodium falciparum importin beta, putative 0.0033 0.0035 0.9177
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0315 0.0628 0.1472
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.002 0.0009 0.0041
Echinococcus multilocularis shaker cognate 0.0315 0.0628 0.0623
Schistosoma mansoni notch 0.0366 0.0737 0.1715
Brugia malayi cation channel family protein 0.0315 0.0628 0.1472
Loa Loa (eye worm) hypothetical protein 0.0181 0.0347 0.0799
Schistosoma mansoni tar DNA-binding protein 0.0102 0.0181 0.0411
Loa Loa (eye worm) hypothetical protein 0.0366 0.0737 0.1715
Echinococcus granulosus microsomal glutathione S transferase 3 0.0045 0.0062 0.0055
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.002 0.0009 0.0041
Echinococcus multilocularis sodium leak channel non selective protein 0.0315 0.0628 0.0623
Echinococcus multilocularis neurogenic locus notch protein 0.0366 0.0737 0.0732
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0319 0.0637 0.0631
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0041 0.0053 0.0109
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.002 0.0009 0.0041
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0035 0.004 0.0532
Echinococcus granulosus potassium voltage gated channel protein 0.0315 0.0628 0.0623
Schistosoma mansoni calcium-activated potassium channel 0.0087 0.015 0.0336
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0026 0.0021 0.0015
Loa Loa (eye worm) PDE1B protein 0.002 0.0009 0.0006
Schistosoma mansoni hypothetical protein 0.0349 0.07 0.1628
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0315 0.0628 0.1472
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0041 0.0053 0.0047
Loa Loa (eye worm) hypothetical protein 0.0223 0.0436 0.1007
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.002 0.0009 0.0041
Schistosoma mansoni calcium-activated potassium channel 0.0402 0.0812 0.1889
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.002 0.0009 0.0006
Loa Loa (eye worm) hypothetical protein 0.0366 0.0737 0.1715
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0018 0.0195
Leishmania major hypothetical protein, unknown function 0.0315 0.0628 0.0623
Echinococcus multilocularis snurportin 1 0.0349 0.07 0.0695
Brugia malayi Calcium binding EGF domain containing protein 0.0366 0.0737 0.1727
Schistosoma mansoni hypothetical protein 0.0061 0.0095 0.0207
Brugia malayi RNA recognition motif domain containing protein 0.0102 0.0181 0.0425
Loa Loa (eye worm) transcription factor SMAD2 0.0117 0.0212 0.0483
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0035 0.004 0.0034
Echinococcus granulosus protein jagged 1 0.0366 0.0737 0.0732
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.002 0.0009 0.0041
Loa Loa (eye worm) voltage-gated calcium channel 0.0315 0.0628 0.1459
Schistosoma mansoni calcium-activated potassium channel 0.0025 0.0019 0.003
Loa Loa (eye worm) hypothetical protein 0.0366 0.0737 0.1715
Onchocerca volvulus 0.0315 0.0628 0.1347
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0009 0.0042
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0366 0.0737 0.1715
Loa Loa (eye worm) hypothetical protein 0.0366 0.0737 0.1715
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.002 0.0009 0.0006
Loa Loa (eye worm) hypothetical protein 0.0315 0.0628 0.1459
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0022 0.0254
Schistosoma mansoni vesicular amine transporter 0.0315 0.0628 0.1459
Echinococcus granulosus inositol monophosphatase 1 0.0035 0.004 0.0034
Entamoeba histolytica hypothetical protein 0.0026 0.0022 0.0982
Toxoplasma gondii hypothetical protein 0.0315 0.0628 0.6405
Echinococcus granulosus hypothetical protein 0.0315 0.0628 0.0623
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0032 0.0034 0.4959
Brugia malayi voltage-dependent calcium channel 0.0315 0.0628 0.1472
Loa Loa (eye worm) hypothetical protein 0.0366 0.0737 0.1715
Schistosoma mansoni voltage-gated potassium channel 0.0315 0.0628 0.1459
Loa Loa (eye worm) hypothetical protein 0.0315 0.0628 0.1459
Brugia malayi EGF-like domain containing protein 0.0366 0.0737 0.1727
Loa Loa (eye worm) hepatopoietin HPO2 0.0026 0.0021 0.0034
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0032 0.0034 0.4959
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0009 0.0042
Leishmania major cAMP-specific phosphodiesterase, putative 0.002 0.0009 0.0003
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0315 0.0628 0.1472
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0048 0.0068 0.0061
Plasmodium falciparum potassium channel 0.0025 0.0019 0.3484
Loa Loa (eye worm) animal heme peroxidase 0.2046 0.427 1
Schistosoma mansoni hypothetical protein 0.0366 0.0737 0.1715
Loa Loa (eye worm) hypothetical protein 0.0048 0.0068 0.0146
Onchocerca volvulus Slit protein homolog 0.0366 0.0737 0.1606
Loa Loa (eye worm) hypothetical protein 0.0315 0.0628 0.1459
Brugia malayi cation channel family protein 0.0315 0.0628 0.1472
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0315 0.0628 0.1472
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.002 0.0009 0.0042
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.002 0.0009 0.0041
Schistosoma mansoni two-pore calcium channel 0.0315 0.0628 0.1459
Loa Loa (eye worm) hypothetical protein 0.2046 0.427 1
Toxoplasma gondii Erv1 / Alr family protein 0.0026 0.0021 0.0125
Schistosoma mansoni notch 0.0366 0.0737 0.1715
Brugia malayi hypothetical protein 0.0315 0.0628 0.1472
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0315 0.0628 0.0623
Onchocerca volvulus 0.0366 0.0737 0.1606
Echinococcus granulosus tumor protein p63 0.0331 0.0662 0.0656
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0006
Echinococcus granulosus Niemann Pick C1 protein 0.0138 0.0256 0.025
Loa Loa (eye worm) blistered cuticle protein 3 0.2046 0.427 1
Loa Loa (eye worm) hypothetical protein 0.0034 0.0038 0.0074
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0315 0.0628 0.0623
Echinococcus multilocularis potassium voltage gated channel protein 0.0315 0.0628 0.0623
Brugia malayi EGF-like domain containing protein 0.0366 0.0737 0.1727
Trichomonas vaginalis importin beta-1, putative 0.0026 0.0022 0.0254
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0319 0.0637 0.1479
Echinococcus granulosus voltage gated potassium channel 0.0319 0.0637 0.0631
Echinococcus granulosus potassium voltage gated channel protein 0.0315 0.0628 0.0623
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0031 0.0032 0.4663
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0319 0.0637 0.1479
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0315 0.0628 0.1459
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0165 0.0314 0.0308
Echinococcus granulosus two pore calcium channel protein 1 0.0315 0.0628 0.0623
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0315 0.0628 0.0623
Echinococcus granulosus two pore calcium channel protein 2 0.0315 0.0628 0.0623
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0315 0.0628 0.0623
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.002 0.0009 0.0006
Echinococcus granulosus transient receptor potential gamma protein 0.0315 0.0628 0.0623
Leishmania major calcium/potassium channel (CAKC), putative 0.0025 0.0019 0.0013
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0061 0.0095 0.0088
Schistosoma mansoni voltage-gated potassium channel 0.0315 0.0628 0.1459
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.002 0.0009 0.0041
Entamoeba histolytica hypothetical protein 0.0069 0.0112 0.6486
Schistosoma mansoni hypothetical protein 0.0366 0.0737 0.1715
Trypanosoma brucei protein kinase, putative 0.0048 0.0068 0.0986
Entamoeba histolytica hypothetical protein 0.0069 0.0112 0.6486
Loa Loa (eye worm) hypothetical protein 0.0366 0.0737 0.1715
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.002 0.0009 0.0003
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0145 0.0272 0.0266
Brugia malayi EGF-like domain containing protein 0.0366 0.0737 0.1727
Loa Loa (eye worm) animal heme peroxidase 0.2046 0.427 1
Leishmania major 4-coumarate:coa ligase-like protein 0.0045 0.0062 0.0055
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0048 0.0068 0.0607
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.002 0.0009 0.0006
Echinococcus multilocularis calcium activated potassium channel variant 0.0087 0.015 0.0144
Echinococcus granulosus expressed conserved protein 0.0091 0.0157 0.0151
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0018 0.3325
Echinococcus multilocularis conserved hypothetical protein 0.0315 0.0628 0.0623
Onchocerca volvulus Peroxidasin homolog 0.2046 0.427 1
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.002 0.0009 0.0041
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.002 0.0009 0.0021
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.002 0.0009 0.0041
Loa Loa (eye worm) inositol-1 0.0035 0.004 0.0079
Brugia malayi RNA binding protein 0.0102 0.0181 0.0425
Leishmania major hypothetical protein, conserved 0.0025 0.0019 0.0013
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0319 0.0637 0.0631
Schistosoma mansoni voltage-gated potassium channel 0.0319 0.0637 0.1479
Schistosoma mansoni hypothetical protein 0.0476 0.0969 0.2257
Echinococcus granulosus shaker cognate 0.0315 0.0628 0.0623
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0102 0.0181 0.0411
Echinococcus multilocularis potassium voltage gated channel protein 0.0315 0.0628 0.0623
Toxoplasma gondii MAPEG family protein 0.0045 0.0062 0.0546
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0319 0.0637 0.0631
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.002 0.0009 0.0003
Echinococcus granulosus protein jagged 2 0.0366 0.0737 0.0732
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0315 0.0628 0.1472
Schistosoma mansoni importin beta-1 0.0033 0.0035 0.0068
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.002 0.0009 0.0041
Brugia malayi GCC2 and GCC3 family protein 0.0366 0.0737 0.1727
Brugia malayi EGF-like domain containing protein 0.0366 0.0737 0.1727
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.002 0.0009 0.0042
Loa Loa (eye worm) calcium channel 0.0315 0.0628 0.1459
Echinococcus multilocularis short transient receptor potential channel 6 0.0315 0.0628 0.0623
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0048 0.0068 0.0061
Schistosoma mansoni voltage-gated cation channel 0.0315 0.0628 0.1459
Loa Loa (eye worm) voltage-gated potassium channel 0.0315 0.0628 0.1459
Loa Loa (eye worm) hypothetical protein 0.0366 0.0737 0.1715
Brugia malayi AMP-binding enzyme family protein 0.0045 0.0062 0.0144
Brugia malayi Cyclic-nucleotide gated cation channel 0.0319 0.0637 0.1491
Echinococcus granulosus voltage dependent calcium channel 0.0315 0.0628 0.0623
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0315 0.0628 1
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.002 0.0009 0.0041
Schistosoma mansoni hypothetical protein 0.0061 0.0095 0.0207
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0315 0.0628 0.0623
Trichomonas vaginalis CMGC family protein kinase 0.0048 0.0068 0.0973
Echinococcus multilocularis survival motor neuron protein 1 0.0223 0.0436 0.043
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.002 0.0009 0.0041
Echinococcus multilocularis microsomal glutathione S transferase 3 0.0045 0.0062 0.0055
Onchocerca volvulus 0.1731 0.3609 0.8429
Schistosoma mansoni hypothetical protein 0.0061 0.0095 0.0207

Activities

Activity type Activity value Assay description Source Reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MALME-3M Melanoma cell line. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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