Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0041 | 0.0054 | 0.1397 | |
Echinococcus multilocularis | sodium:potassium:calcium exchanger 6 | 0.0157 | 0.0242 | 0.0241 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0054 | 0.0054 |
Schistosoma mansoni | hypothetical protein | 0.0157 | 0.0242 | 0.0242 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0007 | 0.0001 | 0.0001 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0007 | 0.0001 | 0.0001 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0007 | 0.0001 | 0.0001 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0041 | 0.0054 | 0.5 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.001 | 0.0005 | 0.0005 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0007 | 0.0001 | 0.0001 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0007 | 0.0001 | 0.0014 |
Echinococcus multilocularis | Pleckstrin G protein, interacting region | 0.001 | 0.0005 | 0.0005 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0007 | 0.0001 | 0.0001 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0007 | 0.0001 | 0.0014 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0031 | 0.0039 | 0.0038 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0007 | 0.0001 | 0.0001 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0007 | 0.0001 | 0.0001 |
Schistosoma mansoni | smad | 0.0009 | 0.0004 | 0.0004 |
Loa Loa (eye worm) | Smad1 | 0.0009 | 0.0004 | 0.0003 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0007 | 0.0001 | 0.0001 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0041 | 0.0054 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0005 | 0.0005 |
Echinococcus multilocularis | caspase 2 | 0.0035 | 0.0045 | 0.0045 |
Schistosoma mansoni | potassium-dependent sodium-calcium exchanger 3 4 | 0.0157 | 0.0242 | 0.0242 |
Onchocerca volvulus | Rap guanine nucleotide exchange factor 1 homolog | 0.0204 | 0.0318 | 0.8253 |
Loa Loa (eye worm) | hypothetical protein | 0.0204 | 0.0318 | 0.0317 |
Echinococcus granulosus | FTZ F1 alpha | 0.0007 | 0.0001 | 0.0001 |
Echinococcus multilocularis | polycomb protein SCMH1 | 0.0055 | 0.0077 | 0.0076 |
Echinococcus granulosus | sodium:potassium:calcium exchanger 6 | 0.0157 | 0.0242 | 0.0241 |
Brugia malayi | beta-lactamase family protein | 0.0041 | 0.0054 | 0.0134 |
Schistosoma mansoni | smad1 5 8 and | 0.0009 | 0.0004 | 0.0004 |
Trichomonas vaginalis | alpha-L-fucosidase, putative | 0.1098 | 0.1755 | 1 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0007 | 0.0001 | 0.0001 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0095 | 0.0142 | 0.0142 |
Onchocerca volvulus | 0.0007 | 0.0001 | 0.0014 | |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0054 | 0.0054 |
Schistosoma mansoni | Smad4 | 0.0009 | 0.0004 | 0.0004 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0054 | 0.0054 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0157 | 0.0242 | 0.1375 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0007 | 0.0001 | 0.0001 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0045 | 0.0045 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0041 | 0.0054 | 0.0054 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0095 | 0.0142 | 0.0142 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0041 | 0.0054 | 0.0054 |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.0062 | 0.0089 | 0.0221 |
Brugia malayi | MH1 domain containing protein | 0.0009 | 0.0004 | 0.0008 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0045 | 0.0045 |
Trichomonas vaginalis | set domain proteins, putative | 0.0246 | 0.0385 | 0.2189 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0259 | 0.0406 | 1 |
Toxoplasma gondii | ABC1 family protein | 0.0041 | 0.0054 | 0.2073 |
Brugia malayi | mbt repeat family protein | 0.0055 | 0.0077 | 0.0191 |
Loa Loa (eye worm) | MBCTL1 | 0.0062 | 0.0089 | 0.0088 |
Brugia malayi | beta-lactamase family protein | 0.0041 | 0.0054 | 0.0134 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.0062 | 0.0089 | 0.0088 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0009 | 0.0004 | 0.0003 |
Loa Loa (eye worm) | hypothetical protein | 0.0007 | 0.0001 | 0.0001 |
Brugia malayi | Cell death protein 3 precursor | 0.0035 | 0.0045 | 0.0112 |
Brugia malayi | regulator of G-protein signaling egl-10 | 0.001 | 0.0005 | 0.0012 |
Brugia malayi | small heat shock protein | 0.0571 | 0.0907 | 0.227 |
Brugia malayi | MH2 domain containing protein | 0.0135 | 0.0206 | 0.0515 |
Schistosoma mansoni | ras GTP exchange factor | 0.0007 | 0.0001 | 0.0001 |
Schistosoma mansoni | na/ca exchanger | 0.0157 | 0.0242 | 0.0242 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0007 | 0.0001 | 0.0001 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0077 | 0.0076 |
Brugia malayi | hypothetical protein | 0.0035 | 0.0045 | 0.0112 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0007 | 0.0001 | 0.0001 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0041 | 0.0054 | 0.0306 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0031 | 0.0039 | 0.0038 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.001 | 0.0005 | 0.0005 |
Echinococcus granulosus | polycomb protein SCMH1 | 0.0055 | 0.0077 | 0.0076 |
Onchocerca volvulus | 0.0041 | 0.0054 | 0.1397 | |
Trypanosoma brucei | hypothetical protein, conserved | 0.0041 | 0.0054 | 0.5 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0.0039 | 0.0039 |
Loa Loa (eye worm) | hypothetical protein | 0.0571 | 0.0907 | 0.0906 |
Echinococcus granulosus | Smad4 | 0.0009 | 0.0004 | 0.0003 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0041 | 0.0054 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0041 | 0.0054 | 0.5 |
Schistosoma mansoni | guanine-nucleotide-exchange-factor | 0.0007 | 0.0001 | 0.0001 |
Echinococcus granulosus | apoptotic protease activating factor 1 | 0.0035 | 0.0045 | 0.0045 |
Trichomonas vaginalis | alpha-L-fucosidase, putative | 0.1098 | 0.1755 | 1 |
Schistosoma mansoni | ras GTP exchange factor son of sevenless | 0.0007 | 0.0001 | 0.0001 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.001 | 0.0005 | 0.0005 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0007 | 0.0001 | 0.0001 |
Brugia malayi | Smad1 | 0.0009 | 0.0004 | 0.0008 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0045 | 0.0045 |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.0062 | 0.0089 | 0.0088 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0007 | 0.0001 | 0.0001 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0007 | 0.0001 | 0.0001 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0041 | 0.0054 | 0.0054 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0.0039 | 0.0039 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0007 | 0.0001 | 0.0001 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0007 | 0.0001 | 0.0001 |
Onchocerca volvulus | Segment polarity protein dishevelled homolog | 0.001 | 0.0005 | 0.0121 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0.0039 | 0.0039 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0007 | 0.0001 | 0.0001 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0041 | 0.0054 | 0.0306 |
Toxoplasma gondii | manganese resistance 1 protein, putative | 0.0157 | 0.0242 | 1 |
Plasmodium vivax | cation/H+ antiporter, putative | 0.0157 | 0.0242 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0005 | 0.0005 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0215 | 0.0334 | 0.0334 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0055 | 0.0077 | 0.0077 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0135 | 0.0206 | 0.0206 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0007 | 0.0001 | 0.0001 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0054 | 0.0054 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0157 | 0.0242 | 0.1375 |
Loa Loa (eye worm) | hypothetical protein | 0.0007 | 0.0001 | 0.0001 |
Onchocerca volvulus | 0.0041 | 0.0054 | 0.1397 | |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.003 | 0.0037 | 0.0036 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0007 | 0.0001 | 0.0001 |
Echinococcus multilocularis | smad | 0.0009 | 0.0004 | 0.0003 |
Echinococcus multilocularis | sodium calcium exchanger | 0.6225 | 1 | 1 |
Loa Loa (eye worm) | DIX domain-containing protein | 0.001 | 0.0005 | 0.0005 |
Schistosoma mansoni | potassium-dependent sodium-calcium exchanger 3 4 | 0.0157 | 0.0242 | 0.0242 |
Schistosoma mansoni | dishevelled | 0.001 | 0.0005 | 0.0005 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0007 | 0.0001 | 0.0001 |
Echinococcus granulosus | sodium:potassium:calcium exchanger | 0.0157 | 0.0242 | 0.0241 |
Loa Loa (eye worm) | hypothetical protein | 0.0157 | 0.0242 | 0.0241 |
Brugia malayi | nuclear hormone receptor | 0.0007 | 0.0001 | 0.0001 |
Loa Loa (eye worm) | hypothetical protein | 0.0007 | 0.0001 | 0.0001 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0009 | 0.0004 | 0.0004 |
Schistosoma mansoni | z-protein (S1r protein) | 0.001 | 0.0005 | 0.0005 |
Brugia malayi | hypothetical protein | 0.001 | 0.0005 | 0.0012 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0031 | 0.0039 | 0.1424 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0041 | 0.0054 | 0.0134 |
Loa Loa (eye worm) | hypothetical protein | 0.0062 | 0.0089 | 0.0088 |
Mycobacterium leprae | Probable ionic transporter integral membrane protein ChaA | 0.0157 | 0.0242 | 1 |
Brugia malayi | N-terminal motif family protein | 0.0204 | 0.0318 | 0.0794 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0007 | 0.0001 | 0.0001 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0041 | 0.0054 | 0.0306 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0054 | 0.0054 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.0062 | 0.0089 | 0.0088 |
Plasmodium vivax | hypothetical protein, conserved | 0.0041 | 0.0054 | 0.0756 |
Echinococcus granulosus | Pleckstrin G protein interacting region | 0.001 | 0.0005 | 0.0005 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0135 | 0.0206 | 0.0206 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0007 | 0.0001 | 0.0001 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0009 | 0.0004 | 0.0003 |
Schistosoma mansoni | sodium/calcium exchanger | 0.6225 | 1 | 1 |
Onchocerca volvulus | 0.001 | 0.0005 | 0.0121 | |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0095 | 0.0142 | 0.0142 |
Schistosoma mansoni | hypothetical protein | 0.0331 | 0.0522 | 0.0522 |
Echinococcus granulosus | segment polarity protein dishevelled | 0.001 | 0.0005 | 0.0005 |
Onchocerca volvulus | Polycomb protein Sfmbt homolog | 0.0055 | 0.0077 | 0.1983 |
Echinococcus granulosus | segment polarity protein dishevelled | 0.001 | 0.0005 | 0.0005 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0005 | 0.0005 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0007 | 0.0001 | 0.0001 |
Mycobacterium ulcerans | hypothetical protein | 0.0041 | 0.0054 | 0.5 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0007 | 0.0001 | 0.0001 |
Brugia malayi | hypothetical protein | 0.001 | 0.0005 | 0.0012 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0055 | 0.0077 | 0.0077 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0041 | 0.0054 | 0.0306 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0007 | 0.0001 | 0.0001 |
Echinococcus multilocularis | Smad4 | 0.0009 | 0.0004 | 0.0003 |
Schistosoma mansoni | fyve finger-containing phosphoinositide kinase fyv1 | 0.001 | 0.0005 | 0.0005 |
Loa Loa (eye worm) | Na/Ca eXchangers family member | 0.0157 | 0.0242 | 0.0241 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0095 | 0.0142 | 0.0355 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0039 | 0.0038 |
Echinococcus granulosus | caspase 2 | 0.0035 | 0.0045 | 0.0045 |
Brugia malayi | Pre-SET motif family protein | 0.0216 | 0.0337 | 0.0842 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0007 | 0.0001 | 0.0001 |
Onchocerca volvulus | 0.0031 | 0.0039 | 0.0998 | |
Brugia malayi | K+-dependent Na+/Ca+ exchanger related-protein | 0.0157 | 0.0242 | 0.0604 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0007 | 0.0001 | 0.0001 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0007 | 0.0001 | 0.0001 |
Schistosoma mansoni | ras GTP exchange factor son of sevenless | 0.0007 | 0.0001 | 0.0001 |
Schistosoma mansoni | coup transcription factor | 0.0007 | 0.0001 | 0.0001 |
Loa Loa (eye worm) | mbt repeat family protein | 0.0055 | 0.0077 | 0.0076 |
Loa Loa (eye worm) | hypothetical protein | 0.0157 | 0.0242 | 0.0241 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0007 | 0.0001 | 0.0001 |
Brugia malayi | Na/Ca eXchangers family member (ncx-4) | 0.0157 | 0.0242 | 0.0604 |
Echinococcus multilocularis | SAM and MBT domain containing protein | 0.0055 | 0.0077 | 0.0076 |
Loa Loa (eye worm) | hypothetical protein | 0.0007 | 0.0001 | 0.0001 |
Mycobacterium ulcerans | beta-lactamase | 0.0041 | 0.0054 | 0.5 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0007 | 0.0001 | 0.0001 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0007 | 0.0001 | 0.0001 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0216 | 0.0337 | 0.0336 |
Echinococcus granulosus | SAM and MBT domain containing protein | 0.0055 | 0.0077 | 0.0076 |
Loa Loa (eye worm) | hypothetical protein | 0.0007 | 0.0001 | 0.0001 |
Mycobacterium ulcerans | lipase LipD | 0.0041 | 0.0054 | 0.5 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0009 | 0.0004 | 0.0003 |
Brugia malayi | mbt repeat family protein | 0.0055 | 0.0077 | 0.0191 |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.0062 | 0.0089 | 0.0089 |
Loa Loa (eye worm) | hypothetical protein | 0.0007 | 0.0001 | 0.0001 |
Onchocerca volvulus | 0.0055 | 0.0077 | 0.1983 | |
Brugia malayi | nuclear receptor NHR-88 | 0.0007 | 0.0001 | 0.0001 |
Echinococcus multilocularis | segment polarity protein dishevelled | 0.001 | 0.0005 | 0.0005 |
Schistosoma mansoni | scm-relatedprotein containing 4 mbt domains (sfmbt) | 0.0055 | 0.0077 | 0.0077 |
Loa Loa (eye worm) | hypothetical protein | 0.249 | 0.3994 | 0.3993 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0007 | 0.0001 | 0.0001 |
Loa Loa (eye worm) | G protein signaling regulator EGL-10 | 0.001 | 0.0005 | 0.0005 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0009 | 0.0004 | 0.0003 |
Brugia malayi | MH2 domain containing protein | 0.0009 | 0.0004 | 0.0008 |
Brugia malayi | ecdysteroid receptor | 0.0007 | 0.0001 | 0.0001 |
Mycobacterium tuberculosis | Probable ionic transporter integral membrane protein ChaA | 0.0157 | 0.0242 | 0.5337 |
Brugia malayi | Domain found in Dishevelled, Egl-10, and Pleckstrin family protein | 0.001 | 0.0005 | 0.0012 |
Brugia malayi | MH2 domain containing protein | 0.0009 | 0.0004 | 0.0008 |
Schistosoma mansoni | smad1 5 8 and | 0.0009 | 0.0004 | 0.0004 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0007 | 0.0001 | 0.0014 |
Onchocerca volvulus | Sodium\/potassium\/calcium exchanger | 0.0157 | 0.0242 | 0.628 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.001 | 0.0005 | 0.0005 |
Onchocerca volvulus | 0.0246 | 0.0385 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0157 | 0.0242 | 0.0241 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0007 | 0.0001 | 0.0001 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0007 | 0.0001 | 0.0001 |
Brugia malayi | MH1 domain containing protein | 0.0009 | 0.0004 | 0.0008 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0007 | 0.0001 | 0.0001 |
Loa Loa (eye worm) | beta-lactamase | 0.0041 | 0.0054 | 0.0054 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0007 | 0.0001 | 0.0001 |
Treponema pallidum | hypothetical protein | 0.0157 | 0.0242 | 0.5 |
Brugia malayi | Pre-SET motif family protein | 0.0031 | 0.0039 | 0.0096 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0007 | 0.0001 | 0.0001 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0215 | 0.0334 | 0.0334 |
Loa Loa (eye worm) | hypothetical protein | 0.0007 | 0.0001 | 0.0001 |
Loa Loa (eye worm) | hypothetical protein | 0.0007 | 0.0001 | 0.0001 |
Schistosoma mansoni | regulator of G protein signaling | 0.001 | 0.0005 | 0.0005 |
Echinococcus granulosus | smad | 0.0009 | 0.0004 | 0.0003 |
Schistosoma mansoni | ras GTP exchange factor son of sevenless | 0.0007 | 0.0001 | 0.0001 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0007 | 0.0001 | 0.0001 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0009 | 0.0004 | 0.0003 |
Schistosoma mansoni | dishevelled | 0.001 | 0.0005 | 0.0005 |
Brugia malayi | beta-lactamase | 0.0041 | 0.0054 | 0.0134 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0041 | 0.0054 | 0.0054 |
Onchocerca volvulus | Cell death protein 3 homolog | 0.0035 | 0.0045 | 0.1168 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0007 | 0.0001 | 0.0001 |
Schistosoma mansoni | smad1 5 8 and | 0.0009 | 0.0004 | 0.0004 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0041 | 0.0054 | 0.5 |
Brugia malayi | Sodium/calcium exchanger protein | 0.249 | 0.3994 | 1 |
Echinococcus multilocularis | sodium:potassium:calcium exchanger | 0.0157 | 0.0242 | 0.0241 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0095 | 0.0142 | 0.0142 |
Brugia malayi | steroid hormone receptor | 0.0007 | 0.0001 | 0.0001 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0007 | 0.0001 | 0.0001 |
Entamoeba histolytica | sodium/calcium exchanger protein, putative | 0.0157 | 0.0242 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0054 | 0.0054 |
Brugia malayi | DIX domain containing protein | 0.001 | 0.0005 | 0.0012 |
Echinococcus multilocularis | segment polarity protein dishevelled | 0.001 | 0.0005 | 0.0005 |
Loa Loa (eye worm) | solute carrier family 8 | 0.6225 | 1 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0095 | 0.0142 | 0.0142 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0031 | 0.0039 | 0.0039 |
Schistosoma mansoni | hypothetical protein | 0.0028 | 0.0034 | 0.0034 |
Brugia malayi | Domain found in Dishevelled, Egl-10, and Pleckstrin family protein | 0.001 | 0.0005 | 0.0012 |
Schistosoma mansoni | caspase-7 (C14 family) | 0.0035 | 0.0045 | 0.0045 |
Schistosoma mansoni | dep domain containing protein | 0.001 | 0.0005 | 0.0005 |
Echinococcus multilocularis | apoptotic protease activating factor 1 | 0.0035 | 0.0045 | 0.0045 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0007 | 0.0001 | 0.0001 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0007 | 0.0001 | 0.0001 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.0062 | 0.0089 | 0.0088 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0095 | 0.0142 | 0.0142 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0007 | 0.0001 | 0.0001 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0007 | 0.0001 | 0.0001 |
Schistosoma mansoni | thyroid hormone receptor | 0.0007 | 0.0001 | 0.0001 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0041 | 0.0054 | 0.0054 |
Schistosoma mansoni | nuclear hormone receptor | 0.0007 | 0.0001 | 0.0001 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0095 | 0.0142 | 0.0142 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0031 | 0.0039 | 0.0038 |
Onchocerca volvulus | 0.0035 | 0.0045 | 0.1168 | |
Plasmodium falciparum | cation/H+ antiporter | 0.0157 | 0.0242 | 0.5 |
Trichomonas vaginalis | esterase, putative | 0.0041 | 0.0054 | 0.0306 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0007 | 0.0001 | 0.0001 |
Schistosoma mansoni | thyroid hormone receptor | 0.0007 | 0.0001 | 0.0001 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0041 | 0.0054 | 0.0306 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0095 | 0.0142 | 0.0142 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0007 | 0.0001 | 0.0001 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0007 | 0.0001 | 0.0001 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0007 | 0.0001 | 0.0001 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0009 | 0.0004 | 0.0003 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0157 | 0.0242 | 0.1375 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0007 | 0.0001 | 0.0001 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.