Detailed information for compound 1653467

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 527.078 | Formula: C27H31ClN4O3S
  • H donors: 4 H acceptors: 2 LogP: 6.78 Rotable bonds: 11
    Rule of 5 violations (Lipinski): 2
  • SMILES: COc1cc(ccc1NC(=O)c1cccc(c1)NC)NC(=S)NC(=O)c1ccc(cc1)C(C)(C)C.Cl
  • InChi: 1S/C27H30N4O3S.ClH/c1-27(2,3)19-11-9-17(10-12-19)24(32)31-26(35)29-21-13-14-22(23(16-21)34-5)30-25(33)18-7-6-8-20(15-18)28-4;/h6-16,28H,1-5H3,(H,30,33)(H2,29,31,32,35);1H
  • InChiKey: QFKFYOLVWLRVQY-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0838 0.1051
Plasmodium vivax phosphodiesterase gamma, putative 0.0074 0.1016 0.1452
Trichomonas vaginalis conserved hypothetical protein 0.0444 0.6602 0.8559
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0047 0.0612 0.0588
Loa Loa (eye worm) hypothetical protein 0.0035 0.0432 0.1066
Loa Loa (eye worm) hypothetical protein 0.0229 0.3364 0.9283
Plasmodium vivax hexose transporter 0.0108 0.1534 0.2214
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0054 0.0064
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0432 0.0521
Schistosoma mansoni glucose transport protein 0.0108 0.1534 0.1512
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0011 0.0069 0.0089
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.001 0.0054 0.0009
Echinococcus multilocularis cysteine protease 0.0016 0.015 0.0125
Schistosoma mansoni glucose transport protein 0.0108 0.1534 0.1512
Echinococcus granulosus lysyl tRNA synthetase 0.0024 0.0268 0.0244
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0432 0.059
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0517 0.7714 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0134 0.0232
Brugia malayi Nuclear hormone receptor family member nhr-14 0.001 0.0054 0.0064
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0018 0.018 0.0454
Loa Loa (eye worm) hypothetical protein 0.0015 0.0134 0.0232
Plasmodium falciparum proline--tRNA ligase 0.0038 0.0474 0.0653
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0134 0.0173
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0838 0.1051
Toxoplasma gondii kinesin motor domain-containing protein 0.0026 0.0299 0.0255
Brugia malayi Pax transcription factor protein 2 0.0246 0.362 1
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0074 0.1016 0.1318
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.001 0.0054 0.0029
Plasmodium falciparum protein kinase 7 0.0305 0.4506 0.6595
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0134 0.0173
Loa Loa (eye worm) hypothetical protein 0.0047 0.0612 0.1572
Trichomonas vaginalis myo-inositol transporter, putative 0.0015 0.0134 0.0173
Loa Loa (eye worm) hypothetical protein 0.0024 0.0268 0.0609
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0074 0.1016 0.1452
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.0574 0.055
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0016 0.015 0.0277
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.015 0.0194
Echinococcus granulosus geminin 0.0164 0.2384 0.2364
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0838 0.1051
Schistosoma mansoni hypothetical protein 0.0047 0.0612 0.0588
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0074 0.1016 0.1318
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.041 0.0531
Loa Loa (eye worm) hypothetical protein 0.0074 0.1016 0.2705
Plasmodium falciparum lysine--tRNA ligase 0.0024 0.0268 0.035
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.001 0.0054 0.0029
Toxoplasma gondii protein kinase, putative 0.0305 0.4506 0.676
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0517 0.7714 1
Echinococcus granulosus synaptic vesicle 2 protein 0.0015 0.0134 0.0109
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0033 0.0404 0.0417
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.018 0.0219
Loa Loa (eye worm) hypothetical protein 0.003 0.0351 0.084
Echinococcus granulosus cysteine protease 0.0008 0.0031 0.0006
Schistosoma mansoni glucose transporter 0.0015 0.0134 0.0109
Loa Loa (eye worm) hypothetical protein 0.0148 0.214 0.5852
Plasmodium falciparum kinesin-5 0.0026 0.0299 0.0395
Brugia malayi photoreceptor-specific nuclear receptor 0.001 0.0054 0.0064
Mycobacterium leprae conserved hypothetical protein 0.0035 0.0432 0.1026
Schistosoma mansoni retinoic acid receptor RXR 0.001 0.0054 0.0029
Plasmodium vivax vivapain-2 0.0016 0.015 0.0175
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0074 0.1016 0.0994
Onchocerca volvulus 0.0016 0.015 0.0268
Onchocerca volvulus 0.0015 0.0134 0.0224
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0033 0.0404 0.0549
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0134 0.0173
Schistosoma mansoni retinoid-x-receptor (RXR) 0.001 0.0054 0.0029
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.1016 0.1282
Loa Loa (eye worm) hypothetical protein 0.0011 0.0069 0.005
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0047 0.0612 0.0588
Brugia malayi Cathepsin L-like cysteine proteinase 0.0011 0.0069 0.0105
Brugia malayi Major Facilitator Superfamily protein 0.0015 0.0134 0.0286
Schistosoma mansoni cpg binding protein 0.0028 0.0325 0.03
Loa Loa (eye worm) hypothetical protein 0.0035 0.0432 0.1066
Mycobacterium tuberculosis Conserved protein 0.0035 0.0432 0.0949
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0015 0.0134 0.0152
Echinococcus granulosus cathepsin L cysteine protease 0.0008 0.0031 0.0006
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0074 0.1016 0.0994
Brugia malayi Latrophilin receptor protein 2 0.0047 0.0612 0.1619
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0074 0.1016 0.1364
Mycobacterium ulcerans hypothetical protein 0.0035 0.0432 0.1567
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0235 0.3449 0.4471
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0047 0.0612 0.0588
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.0574 0.055
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0156 0.2263 1
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0074 0.1016 0.0994
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.015 0.0194
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.1016 0.1282
Brugia malayi Sugar transporter family protein 0.0015 0.0134 0.0286
Brugia malayi Cathepsin L-like precursor 0.0016 0.015 0.0331
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0074 0.1016 0.1452
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0018 0.018 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0054 0.0009
Treponema pallidum exodeoxyribonuclease (exoA) 0.0018 0.018 1
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0432 0.1066
Giardia lamblia Prolyl-tRNA synthetase 0.0032 0.0393 0.1219
Toxoplasma gondii lysine-tRNA ligase 0.0024 0.0268 0.0208
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0517 0.7714 0.7708
Plasmodium falciparum mitogen-activated protein kinase 2 0.0174 0.2537 0.3692
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0074 0.1016 0.1318
Loa Loa (eye worm) sugar transporter 0.0015 0.0134 0.0232
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0134 0.0173
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0021 0.0224 0.029
Brugia malayi Calcitonin receptor-like protein seb-1 0.0148 0.214 0.5875
Echinococcus multilocularis FTZ F1 alpha 0.001 0.0054 0.0029
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0235 0.3449 0.3432
Loa Loa (eye worm) hypothetical protein 0.0015 0.0134 0.0232
Trypanosoma cruzi hexose transporter, putative 0.0015 0.0134 0.0134
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0134 0.0173
Trypanosoma brucei sugar transporter, putative 0.0015 0.0134 0.0134
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0083 0.1151 0.1129
Brugia malayi beta-lactamase family protein 0.0035 0.0432 0.1116
Onchocerca volvulus 0.0016 0.015 0.0268
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.018 0.0362
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0074 0.1016 0.0994
Loa Loa (eye worm) latrophilin receptor protein 2 0.0047 0.0612 0.1572
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.001 0.0054 0.0009
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0517 0.7714 1
Entamoeba histolytica protein kinase, putative 0.0033 0.0404 1
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0047 0.0612 0.1619
Onchocerca volvulus 0.0011 0.0069 0.0041
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0024 0.0268 0.0258
Echinococcus granulosus dnaJ subfamily B 0.0396 0.5888 0.5878
Onchocerca volvulus 0.0246 0.362 1
Schistosoma mansoni hypothetical protein 0.0396 0.5888 0.5878
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0517 0.7714 1
Schistosoma mansoni microtubule-associated protein tau 0.0669 1 1
Echinococcus granulosus retinoic acid receptor rxr beta a 0.001 0.0054 0.0029
Trichomonas vaginalis glucose transporter, putative 0.0033 0.041 0.0531
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0074 0.1016 0.1282
Echinococcus multilocularis ecdysone induced protein 78C 0.001 0.0054 0.0029
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.015 0.0194
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0351 0.0326
Schistosoma mansoni lamin 0.0026 0.0299 0.0275
Brugia malayi Pre-SET motif family protein 0.0202 0.2959 0.8157
Echinococcus granulosus solute carrier family 22 0.0015 0.0134 0.0109
Trypanosoma cruzi cruzipain precursor, putative 0.0062 0.0838 0.1051
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0074 0.1016 0.1364
Loa Loa (eye worm) hypothetical protein 0.0016 0.015 0.0277
Leishmania major hypothetical protein, conserved 0.0074 0.1016 0.1164
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.015 0.0194
Echinococcus multilocularis kinesin family 1 0.0201 0.2937 0.2919
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0838 0.1051
Echinococcus granulosus survival motor neuron protein 1 0.0229 0.3364 0.3347
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0074 0.1016 0.1452
Toxoplasma gondii facilitative glucose transporter GT1 0.0108 0.1534 0.2164
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0018 0.018 0.3998
Entamoeba histolytica hypothetical protein 0.0024 0.0268 0.6371
Brugia malayi Cathepsin L-like precursor 0.0016 0.015 0.0331
Schistosoma mansoni cpg binding protein 0.0029 0.0349 0.0324
Entamoeba histolytica cysteine protease, putative 0.0016 0.015 0.3188
Brugia malayi Cathepsin L-like precursor 0.0011 0.0069 0.0105
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0074 0.1016 0.1318
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.001 0.0054 0.0029
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0299 0.0696
Brugia malayi Sugar transporter family protein 0.0108 0.1534 0.4186
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0356 0.5281 0.6846
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0074 0.1016 0.1364
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0432 0.0559
Brugia malayi hypothetical protein 0.0015 0.0134 0.0286
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.015 0.0194
Leishmania major hypothetical protein, conserved 0.0035 0.0432 0.0393
Loa Loa (eye worm) hypothetical protein 0.0035 0.0432 0.1066
Brugia malayi beta-lactamase 0.0035 0.0432 0.1116
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0838 0.1051
Echinococcus multilocularis cpg binding protein 0.0029 0.0349 0.0324
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0074 0.1016 0.1364
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0134 0.0173
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0044 0.0574 0.1466
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.001 0.0054 0.0029
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0134 0.0173
Loa Loa (eye worm) hypothetical protein 0.001 0.0054 0.0009
Trypanosoma cruzi major cysteine proteinase, putative 0.0049 0.0638 0.0791
Onchocerca volvulus 0.0015 0.0134 0.0224
Mycobacterium ulcerans sugar transporter 0.0015 0.0134 0.025
Trypanosoma cruzi cysteine peptidase, putative 0.0016 0.015 0.0155
Brugia malayi Cathepsin L-like precursor 0.0011 0.0069 0.0105
Trypanosoma brucei THT1 - hexose transporter, putative 0.0033 0.041 0.0493
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0134 0.0173
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0033 0.0404 0.0379
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.018 0.0061
Trichomonas vaginalis conserved hypothetical protein 0.0444 0.6602 0.8559
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0134 0.0173
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0517 0.7714 1
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0134 0.0173
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.001 0.0054 0.0029
Schistosoma mansoni sugar transporter 0.0015 0.0134 0.0109
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0156 0.2263 0.3292
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.015 0.0194
Trypanosoma brucei glucose transporter, putative 0.0033 0.041 0.0493
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0156 0.2263 0.2243
Echinococcus granulosus cathepsin l1 0.0011 0.0069 0.0044
Echinococcus granulosus solute carrier family 22 0.0015 0.0134 0.0109
Loa Loa (eye worm) hypothetical protein 0.0035 0.0432 0.1066
Echinococcus granulosus intermediate filament protein 0.0026 0.0299 0.0275
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0517 0.7714 1
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0235 0.3449 0.3432
Onchocerca volvulus 0.0015 0.0134 0.0224
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0108 0.1534 0.1512
Schistosoma mansoni intermediate filament proteins 0.0026 0.0299 0.0275
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0838 0.1051
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0074 0.1016 0.1452
Onchocerca volvulus 0.0026 0.0299 0.0688
Plasmodium falciparum calcium-dependent protein kinase 2 0.0033 0.0404 0.0549
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0517 0.7714 0.7708
Plasmodium falciparum calcium-dependent protein kinase 3 0.0033 0.0404 0.0549
Mycobacterium ulcerans putative regulatory protein 0.0161 0.2337 1
Brugia malayi Major Facilitator Superfamily protein 0.0015 0.0134 0.0286
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0517 0.7714 1
Brugia malayi hypothetical protein 0.0229 0.3364 0.9287
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0432 0.0559
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0024 0.0268 0.0309
Schistosoma mansoni sugar transporter 0.0015 0.0134 0.0109
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0235 0.3449 0.9523
Leishmania major glucose transporter, lmgt3 0.0033 0.041 0.0364
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0134 0.0173
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0838 0.1051
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0134 0.0173
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.018 0.0155
Plasmodium falciparum phosphodiesterase gamma, putative 0.0074 0.1016 0.1452
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0074 0.1016 0.2745
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0517 0.7714 1
Plasmodium vivax lysine--tRNA ligase, putative 0.0024 0.0268 0.035
Trypanosoma brucei glucose transporter 1E 0.0033 0.041 0.0493
Echinococcus granulosus solute carrier family 22 0.0015 0.0134 0.0109
Leishmania major cathepsin L-like protease 0.0016 0.015 0.0021
Onchocerca volvulus 0.0016 0.015 0.0268
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.018 0.0155
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0148 0.214 0.5875
Brugia malayi F/Y-rich N-terminus family protein 0.001 0.0049 0.0051
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.001 0.0054 0.0009
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0517 0.7714 1
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0033 0.0404 0.0379
Loa Loa (eye worm) hypothetical protein 0.0015 0.0134 0.0232
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0074 0.1016 0.2745
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0044 0.0574 0.1513
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0134 0.0173
Brugia malayi cathepsin L-like precursor 0.0011 0.0069 0.0105
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0116 0.0183
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0838 0.1051
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0517 0.7714 1
Loa Loa (eye worm) ctsf protein 0.0016 0.015 0.0277
Schistosoma mansoni protein kinase 0.0033 0.0404 0.0379
Brugia malayi Kinesin motor domain containing protein 0.0026 0.0299 0.0746
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0033 0.0404 0.0485
Schistosoma mansoni protein kinase 0.0033 0.0404 0.0379
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0032 0.0393 0.0369
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0054 0.0064
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0074 0.1016 0.1282
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0074 0.1016 0.1364
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0015 0.0134 0.025
Entamoeba histolytica cysteine proteinase, putative 0.0011 0.0069 0.1014
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0432 0.0407
Schistosoma mansoni cathepsin F (C01 family) 0.0016 0.015 0.0125
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0432 0.1567
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0432 0.0407
Loa Loa (eye worm) hypothetical protein 0.0074 0.1016 0.2705
Brugia malayi nuclear hormone receptor 0.001 0.0054 0.0064
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0056 0.0757 0.0945
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0235 0.3449 0.9523
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.015 0.0194
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0032 0.0393 0.0369
Trypanosoma cruzi hexose transporter, putative 0.0033 0.041 0.0493
Schistosoma mansoni hypothetical protein 0.0164 0.2384 0.2364
Schistosoma mansoni RAR-like nuclear receptor 0.001 0.0054 0.0029
Echinococcus granulosus cathepsin L 0.0008 0.0031 0.0006
Onchocerca volvulus 0.0015 0.0134 0.0224
Toxoplasma gondii hypothetical protein 0.0161 0.2337 0.3407
Trichomonas vaginalis conserved hypothetical protein 0.0161 0.2337 0.303
Onchocerca volvulus Huntingtin homolog 0.0119 0.1697 0.4607
Loa Loa (eye worm) hypothetical protein 0.0032 0.0393 0.096
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0134 0.0173
Onchocerca volvulus 0.0015 0.0134 0.0224
Loa Loa (eye worm) major facilitator superfamily transporter 0.0015 0.0134 0.0232
Toxoplasma gondii exonuclease III APE 0.0018 0.018 0.0071
Onchocerca volvulus 0.0015 0.0134 0.0224
Onchocerca volvulus Putative transporter 0.0015 0.0134 0.0224
Echinococcus granulosus General substrate transporter 0.0093 0.1305 0.1282
Brugia malayi steroid hormone receptor 0.001 0.0054 0.0064
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0517 0.7714 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0838 0.1051
Schistosoma mansoni hypothetical protein 0.0164 0.2384 0.2364
Schistosoma mansoni lamin 0.0026 0.0299 0.0275
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0074 0.1016 0.0994
Loa Loa (eye worm) hypothetical protein 0.0161 0.2337 0.6406
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.001 0.0054 0.0009
Trichomonas vaginalis esterase, putative 0.0035 0.0432 0.0559
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0517 0.7714 1
Onchocerca volvulus 0.0015 0.0134 0.0224
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.041 0.0531
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.1016 0.1282
Schistosoma mansoni glucose transport protein 0.0108 0.1534 0.1512
Echinococcus granulosus solute carrier family 22 0.0015 0.0134 0.0109
Trypanosoma brucei glucose transporter, putative 0.0033 0.041 0.0493
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0033 0.0404 0.0988
Echinococcus granulosus lamin 0.0026 0.0299 0.0275
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0134 0.0173
Echinococcus multilocularis cathepsin L 0.0008 0.0031 0.0006
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0356 0.5281 0.6846
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0432 0.0521
Echinococcus granulosus Sugar transporter ERD6 protein 0.0015 0.0134 0.0109
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.001 0.0054 0.0029
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0016 0.015 0.0194
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0054 0.0029
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0432 0.0949
Loa Loa (eye worm) hypothetical protein 0.0235 0.3449 0.952
Schistosoma mansoni nuclear hormone receptor 0.001 0.0054 0.0029
Brugia malayi Papain family cysteine protease containing protein 0.0016 0.015 0.0331
Brugia malayi CXXC zinc finger family protein 0.0028 0.0325 0.0819
Loa Loa (eye worm) sugar transporter 0.0108 0.1534 0.4154
Echinococcus multilocularis musashi 0.0026 0.0299 0.0275
Plasmodium falciparum cysteine proteinase falcipain 3 0.0016 0.015 0.0175
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0074 0.1016 0.2705
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0351 0.0326
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0432 0.1116
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0033 0.0404 0.0417
Onchocerca volvulus Huntingtin homolog 0.0119 0.1697 0.4607
Schistosoma mansoni sugar transporter 0.0015 0.0134 0.0109
Plasmodium falciparum GAF domain-related protein, putative 0.0161 0.2337 0.3399
Brugia malayi Nuclear hormone receptor family member nhr-31 0.001 0.0054 0.0064
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0074 0.1016 0.2745
Trypanosoma brucei glucose transporter, putative 0.0033 0.041 0.0493
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0517 0.7714 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0054 0.0064
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0074 0.1016 0.1452
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0351 0.0335
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0108 0.1534 0.1512
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0051 0.0026
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.015 0.0194
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0134 0.0173
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0074 0.1016 0.1364
Loa Loa (eye worm) hypothetical protein 0.0015 0.0134 0.0232
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0024 0.0268 0.0309
Onchocerca volvulus Cathepsin L homolog 0.0016 0.015 0.0268
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0074 0.1016 0.1364
Trichomonas vaginalis conserved hypothetical protein 0.0517 0.7714 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.015 0.0194
Loa Loa (eye worm) hypothetical protein 0.0035 0.0432 0.1066
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0074 0.1016 0.1364
Brugia malayi Cathepsin L-like precursor 0.0016 0.015 0.0331
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.0574 0.055
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0054 0.0064
Brugia malayi Steroid receptor seven-up type 2 0.001 0.0054 0.0064
Loa Loa (eye worm) hypothetical protein 0.0015 0.0134 0.0232
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0223 0.327 1
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0517 0.7714 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0134 0.0232
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0008 0.0031 0.0006
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0517 0.7714 1
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0074 0.1016 0.0994
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0134 0.0173
Loa Loa (eye worm) hypothetical protein 0.0026 0.0292 0.0676
Echinococcus multilocularis GPCR, family 2 0.0047 0.0612 0.0588
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0517 0.7714 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0016 0.015 0.0194
Brugia malayi Cathepsin L-like precursor 0.0016 0.015 0.0331
Entamoeba histolytica kinesin, putative 0.0026 0.0299 0.7187
Loa Loa (eye worm) hypothetical protein 0.0011 0.0069 0.005
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0134 0.0173
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.018 0.0194
Echinococcus granulosus cathepsin l cysteine peptidase 0.0016 0.015 0.0125
Onchocerca volvulus 0.0015 0.0134 0.0224
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.0574 0.055
Trichomonas vaginalis conserved hypothetical protein 0.0074 0.1016 0.1318
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.001 0.0054 0.0029
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.001 0.0054 0.0009
Plasmodium falciparum calcium-dependent protein kinase 5 0.0033 0.0404 0.0549
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0134 0.0173
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0015 0.0134 0.0109
Loa Loa (eye worm) hypothetical protein 0.0015 0.0134 0.0232
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0018 0.018 0.0217
Loa Loa (eye worm) hypothetical protein 0.0012 0.0088 0.0104
Loa Loa (eye worm) cysteine protease 0.0016 0.015 0.0277
Loa Loa (eye worm) hypothetical protein 0.0035 0.0432 0.1066
Echinococcus granulosus ecdysone induced protein 78C 0.001 0.0054 0.0029
Plasmodium falciparum protein kinase 6 0.0458 0.6817 1
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0161 0.2337 1
Leishmania major glucose transporter/membrane transporter D2, putative 0.0033 0.041 0.0364
Leishmania major cathepsin L-like protease 0.0016 0.015 0.0021
Brugia malayi hypothetical protein 0.0015 0.0134 0.0286
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.002 0.0214 0.0254
Chlamydia trachomatis lysine--tRNA ligase 0.0024 0.0268 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0134 0.0232
Echinococcus multilocularis solute carrier family 22 0.0015 0.0134 0.0109
Onchocerca volvulus 0.0015 0.0134 0.0224
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0074 0.1016 0.1282
Leishmania major glucose transporter, lmgt2 0.0033 0.041 0.0364
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0074 0.1016 0.1364
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0517 0.7714 1
Plasmodium vivax proline--tRNA ligase, putative 0.0038 0.0474 0.0653
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0054 0.0029
Schistosoma mansoni hypothetical protein 0.0101 0.1433 0.1411
Plasmodium vivax vivapain-2 0.0016 0.015 0.0175
Mycobacterium tuberculosis Conserved protein 0.0035 0.0432 0.0949
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0517 0.7714 1
Schistosoma mansoni ap endonuclease 0.0018 0.018 0.0155
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0432 0.0559
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0108 0.1534 0.1512
Brugia malayi ecdysteroid receptor 0.001 0.0054 0.0064
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0033 0.0404 0.0988
Brugia malayi beta-lactamase family protein 0.0035 0.0432 0.1116
Echinococcus granulosus cathepsin L cysteine proteinase 0.0016 0.015 0.0125
Schistosoma mansoni coup transcription factor 0.001 0.0054 0.0029
Trypanosoma brucei THT1 - hexose transporter, putative 0.0033 0.041 0.0493
Brugia malayi major facilitator superfamily protein 0.0015 0.0134 0.0286
Loa Loa (eye worm) hypothetical protein 0.001 0.0054 0.0009
Plasmodium vivax hypothetical protein, conserved 0.0161 0.2337 0.3399
Loa Loa (eye worm) hypothetical protein 0.001 0.0054 0.0009
Leishmania major cysteine peptidase A (CPA) 0.0016 0.015 0.0021
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0008 0.0031 0.004
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0051 0.0026
Leishmania major hypothetical protein, conserved 0.0074 0.1016 0.1164
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0033 0.0404 0.1038
Loa Loa (eye worm) hypothetical protein 0.0015 0.0134 0.0232
Echinococcus multilocularis lamin dm0 0.0026 0.0299 0.0275
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0038 0.0474 0.0527
Schistosoma mansoni ap endonuclease 0.0018 0.018 0.0155
Loa Loa (eye worm) hypothetical protein 0.0015 0.0134 0.0232
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0074 0.1016 0.1282
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0108 0.1534 0.1512
Entamoeba histolytica cysteine proteinase, putative 0.0016 0.015 0.3188
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0074 0.1016 0.2745
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0235 0.3449 0.4471
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0054 0.0064
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0432 0.0407
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0134 0.0173
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0574 0.055
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0033 0.0404 0.0379
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.1016 0.1282
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0047 0.0612 0.0588
Leishmania major cathepsin L-like protease 0.0016 0.015 0.0021
Trypanosoma cruzi hexose transporter, putative 0.0018 0.0181 0.0195
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0432 0.0559
Loa Loa (eye worm) PDE1B protein 0.0074 0.1016 0.2705
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0432 0.0407
Plasmodium vivax SET domain protein, putative 0.003 0.0351 0.0471
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0024 0.0268 0.0845
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0134 0.0173
Brugia malayi Major Facilitator Superfamily protein 0.0015 0.0134 0.0286
Toxoplasma gondii cathepsin CPL 0.0016 0.015 0.0025
Trypanosoma cruzi glucose transporter, putative 0.0015 0.0134 0.0134
Loa Loa (eye worm) hypothetical protein 0.001 0.0054 0.0009
Schistosoma mansoni hypothetical protein 0.0047 0.0612 0.0588
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.018 0.0194
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0108 0.1534 0.1512
Echinococcus granulosus GPCR family 2 0.0047 0.0612 0.0588
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0074 0.1016 0.1364
Brugia malayi latrophilin 2 splice variant baaae 0.0101 0.1433 0.3905
Brugia malayi Nuclear hormone receptor-like 1 0.001 0.0054 0.0064
Schistosoma mansoni lysyl-tRNA synthetase 0.0024 0.0268 0.0244
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0074 0.1016 0.0994
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.001 0.0054 0.0009
Loa Loa (eye worm) pax transcription factor protein 2 0.0246 0.362 1
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0432 0.0949
Brugia malayi hypothetical protein 0.0119 0.1697 0.4642
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0074 0.1016 0.1364
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.015 0.0194
Toxoplasma gondii hypothetical protein 0.0444 0.6602 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0088 0.0104
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0016 0.015 0.0125
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0083 0.1151 0.3122
Loa Loa (eye worm) hypothetical protein 0.0119 0.1697 0.4612
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0016 0.015 0.0175
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0033 0.0404 0.0379
Echinococcus multilocularis calcium dependent protein kinase 0.0031 0.0373 0.0348
Mycobacterium leprae conserved hypothetical protein 0.0161 0.2337 1
Brugia malayi major facilitator superfamily protein 0.0015 0.0134 0.0286
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0325 0.0301
Loa Loa (eye worm) hypothetical protein 0.0101 0.1433 0.3871
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0108 0.1534 0.1512
Loa Loa (eye worm) beta-lactamase 0.0035 0.0432 0.1066
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0325 0.0768
Echinococcus granulosus cathepsin l1 0.0016 0.015 0.0125
Loa Loa (eye worm) hypothetical protein 0.0032 0.0393 0.096
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0156 0.2263 0.2243
Loa Loa (eye worm) hypothetical protein 0.001 0.0054 0.0009
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0008 0.0031 0.004
Echinococcus multilocularis General substrate transporter 0.0093 0.1305 0.1282
Trichomonas vaginalis conserved hypothetical protein 0.0444 0.6602 0.8559
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0432 0.0949
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0351 0.0326
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0134 0.0173
Echinococcus multilocularis lamin 0.0026 0.0299 0.0275
Schistosoma mansoni cathepsin F (C01 family) 0.0016 0.015 0.0125
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.018 0.0233
Brugia malayi Pre-SET motif family protein 0.003 0.0351 0.0891
Schistosoma mansoni serine/threonine protein kinase 0.0033 0.0404 0.0379
Onchocerca volvulus 0.0015 0.0134 0.0224
Echinococcus multilocularis cathepsin L cysteine protease 0.0016 0.015 0.0125
Loa Loa (eye worm) hypothetical protein 0.0015 0.0134 0.0232
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0074 0.1016 0.1364
Giardia lamblia hypothetical protein 0.0074 0.1016 0.4145
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0838 0.1051
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0351 0.0326
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0074 0.1016 0.0994
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0299 0.0748
Onchocerca volvulus 0.0035 0.0432 0.1058
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0156 0.2263 0.2243
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.001 0.0054 0.0029
Brugia malayi Nuclear hormone receptor family member nhr-41 0.001 0.0054 0.0064
Leishmania major cathepsin L-like protease 0.0016 0.015 0.0021
Onchocerca volvulus Cathepsin F homolog 0.0016 0.015 0.0268
Onchocerca volvulus 0.0016 0.015 0.0268
Loa Loa (eye worm) hypothetical protein 0.001 0.0054 0.0009
Brugia malayi Nuclear hormone receptor family member nhr-3 0.001 0.0054 0.0064
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0161 0.2337 0.7027
Loa Loa (eye worm) fibroinase 0.0016 0.015 0.0277
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0013 0.0105 0.0153
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0838 0.1051
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0517 0.7714 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.015 0.0194
Loa Loa (eye worm) steroid hormone receptor 0.001 0.0054 0.0009
Loa Loa (eye worm) hypothetical protein 0.001 0.0054 0.0009
Trypanosoma brucei THT1 - hexose transporter, putative 0.0033 0.041 0.0493
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.061 0.1614
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0032 0.0393 0.0369
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0038 0.0474 0.0577
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0116 0.0237
Leishmania major cathepsin L-like protease 0.0062 0.0838 0.0929
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0517 0.7714 1
Plasmodium vivax calcium-dependent protein kinase, putative 0.0033 0.0404 0.0549
Leishmania major lysyl-tRNA synthetase, putative 0.0024 0.0268 0.0177
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.015 0.0194
Onchocerca volvulus 0.0026 0.0299 0.0688
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0074 0.1016 0.1364
Onchocerca volvulus 0.0047 0.061 0.156
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0015 0.0134 0.0109
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.018 0.0415
Echinococcus multilocularis lysyl tRNA synthetase 0.0024 0.0268 0.0244
Onchocerca volvulus 0.0035 0.0432 0.1058
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0517 0.7714 1
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0517 0.7714 1
Trichomonas vaginalis set domain proteins, putative 0.023 0.3379 0.4381
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0432 0.0949
Plasmodium vivax CDK-related protein kinase 6, putative 0.0458 0.6817 1
Entamoeba histolytica protein kinase, putative 0.0033 0.0404 1
Leishmania major protein kinase, putative 0.0033 0.0404 0.0356
Onchocerca volvulus 0.0028 0.0325 0.076
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0024 0.0268 0.0348
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0008 0.0031 0.0006
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.1016 0.1282
Mycobacterium tuberculosis Conserved protein 0.0035 0.0432 0.0949
Trichomonas vaginalis sugar transport protein, putative 0.0015 0.0134 0.0173
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0016 0.015 0.0175
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0517 0.7714 1
Onchocerca volvulus 0.023 0.3379 0.9324
Trichomonas vaginalis conserved hypothetical protein 0.0108 0.1534 0.1988
Leishmania major cathepsin L-like protease 0.0062 0.0838 0.0929
Onchocerca volvulus 0.0015 0.0134 0.0224
Echinococcus granulosus calcium dependent protein kinase 0.0031 0.0373 0.0348
Leishmania major cathepsin L-like protease 0.0016 0.015 0.0021
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0074 0.1016 0.1364
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0134 0.0173
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0432 0.1567
Leishmania major glucose transporter, lmgt1 0.0033 0.041 0.0364
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0074 0.1016 0.1452
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0517 0.7714 1
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0032 0.0393 0.101
Trypanosoma cruzi hexose transporter, putative 0.0033 0.041 0.0493
Schistosoma mansoni hypothetical protein 0.0047 0.0612 0.0588
Brugia malayi Cathepsin L-like precursor 0.0016 0.015 0.0331
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0156 0.2263 0.2243
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.015 0.0194
Trypanosoma brucei glucose transporter, putative 0.0033 0.041 0.0493
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0235 0.3449 0.3432
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0432 0.0949
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0517 0.7714 1
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0517 0.7714 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0134 0.0232
Trichomonas vaginalis glucose transporter, putative 0.0033 0.041 0.0531
Brugia malayi Cam kinase protein 1 0.0033 0.0404 0.1038
Trypanosoma cruzi sugar transporter, putative 0.0015 0.0134 0.0134
Trypanosoma brucei glucose transporter, putative 0.0033 0.041 0.0493
Echinococcus multilocularis thyroid hormone receptor alpha 0.001 0.0054 0.0029
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0108 0.1534 0.1512
Loa Loa (eye worm) hypothetical protein 0.0119 0.1697 0.4612
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.015 0.0194
Mycobacterium ulcerans integral membrane transport protein 0.0015 0.0134 0.025
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0038 0.0474 0.0449
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0074 0.1016 0.1318
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0351 0.0326
Schistosoma mansoni hypothetical protein 0.0047 0.061 0.0587
Loa Loa (eye worm) hypothetical protein 0.0156 0.2263 0.6197
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.015 0.0194
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0134 0.0173
Brugia malayi Sugar transporter family protein 0.0015 0.0134 0.0286
Echinococcus multilocularis cysteine protease 0.0016 0.015 0.0125
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0148 0.214 0.5852
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.015 0.0194
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0174 0.2537 0.3715
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0156 0.2263 0.2243
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0074 0.1016 0.0994
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.018 0.0194
Leishmania major cAMP-specific phosphodiesterase, putative 0.0074 0.1016 0.1164
Trichomonas vaginalis sugar transporter, putative 0.0033 0.041 0.0531
Mycobacterium leprae Probable lipase LipE 0.0035 0.0432 0.1026
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0054 0.0029
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0161 0.2337 0.7027
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0351 0.0326
Trypanosoma brucei glucose transporter, putative 0.0033 0.041 0.0493
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.015 0.0194
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0015 0.0134 0.025
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0032 0.0393 0.051
Loa Loa (eye worm) hypothetical protein 0.0033 0.0404 0.0988
Echinococcus multilocularis solute carrier family 22 0.0015 0.0134 0.0109
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0517 0.7714 0.7708
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0074 0.1016 0.1452
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0517 0.7714 1
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0351 0.0326
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0838 0.1051
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0432 0.0521
Echinococcus multilocularis microtubule associated protein 2 0.0669 1 1
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.018 0.0219
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0054 0.0029
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0074 0.1016 0.0994
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0032 0.0393 0.9729
Onchocerca volvulus 0.0015 0.0134 0.0224
Plasmodium vivax kinesin-5 0.0026 0.0299 0.0395
Brugia malayi nuclear receptor NHR-88 0.001 0.0054 0.0064
Plasmodium falciparum hexose transporter 0.0108 0.1534 0.2214
Trichomonas vaginalis sugar transporter, putative 0.0033 0.041 0.0531
Toxoplasma gondii histone lysine methyltransferase SET1 0.0054 0.0717 0.0901
Schistosoma mansoni survival motor neuron protein 0.0047 0.061 0.0587
Schistosoma mansoni kinesin eg-5 0.0026 0.0299 0.0274
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.0812 0.0789
Plasmodium falciparum calcium-dependent protein kinase 4 0.0033 0.0404 0.0549
Plasmodium vivax sugar transporter, putative 0.0015 0.0134 0.0152
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.001 0.0054 0.0029
Trypanosoma brucei hypothetical protein, conserved 0.0074 0.1016 0.1282
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0134 0.0173
Echinococcus granulosus lamin dm0 0.0026 0.0299 0.0275
Brugia malayi lysyl-tRNA synthetase 0.0024 0.0268 0.0661
Trichomonas vaginalis sugar transporter, putative 0.0033 0.041 0.0531
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0074 0.1016 0.1282
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0838 0.1051
Loa Loa (eye worm) kinesin-like protein KLP2 0.0026 0.0299 0.0694
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0074 0.1016 0.1318
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0432 0.0949
Toxoplasma gondii ABC1 family protein 0.0035 0.0432 0.046
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0517 0.7714 1
Echinococcus multilocularis solute carrier family 22 0.0015 0.0134 0.0109
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0074 0.1016 0.1318
Leishmania major cathepsin L-like protease 0.0062 0.0838 0.0929
Brugia malayi Cathepsin L-like precursor 0.0016 0.015 0.0331
Echinococcus multilocularis cathepsin L cysteine protease 0.0016 0.015 0.0125
Schistosoma mansoni thyroid hormone receptor 0.001 0.0054 0.0029
Brugia malayi Nuclear hormone receptor family member nhr-49 0.001 0.0054 0.0064
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0174 0.2537 0.3692
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.001 0.0054 0.0029
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0134 0.0173
Schistosoma mansoni cathepsin F (C01 family) 0.0011 0.0069 0.0044
Trypanosoma brucei glucose transporter, putative 0.0033 0.041 0.0493
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0038 0.0474 0.0449
Loa Loa (eye worm) hypothetical protein 0.0015 0.0134 0.0232
Toxoplasma gondii GAF domain-containing protein 0.0161 0.2337 0.3407
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0054 0.0064
Onchocerca volvulus 0.0035 0.0432 0.1058
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.015 0.0194
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0074 0.1016 0.1318
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0074 0.1016 0.1164
Schistosoma mansoni Tr4/Tr2 (homologue) 0.001 0.0054 0.0029
Mycobacterium ulcerans putative regulatory protein 0.0161 0.2337 1
Brugia malayi Nuclear hormone receptor family member nhr-40 0.001 0.0054 0.0064
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0011 0.0069 0.0089
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0134 0.0173
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.001 0.0054 0.0029
Onchocerca volvulus 0.0015 0.0134 0.0224
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0299 0.0696
Onchocerca volvulus 0.003 0.0351 0.0832
Echinococcus granulosus cpg binding protein 0.0029 0.0349 0.0324
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0134 0.0173
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0574 0.055
Onchocerca volvulus 0.0015 0.0134 0.0224
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0074 0.1016 0.1318
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0074 0.1016 0.1318
Trypanosoma cruzi hexose transporter 0.0033 0.041 0.0493
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0134 0.0173
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0134 0.0173
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0074 0.1016 0.1282
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0838 0.1051
Brugia malayi Nuclear hormone receptor family member nhr-1 0.001 0.0054 0.0064
Mycobacterium ulcerans beta-lactamase 0.0035 0.0432 0.1567
Loa Loa (eye worm) hypothetical protein 0.0013 0.0095 0.0124
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0032 0.0393 0.0847
Giardia lamblia Kinesin-5 0.0026 0.0299 0.0775
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A 0.0083 0.1151 0.3084
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0074 0.1016 0.0994
Echinococcus multilocularis dnaJ subfamily B 0.0396 0.5888 0.5878
Trichomonas vaginalis glucose transporter, putative 0.0015 0.0134 0.0173
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0074 0.1016 0.1282
Trichomonas vaginalis conserved hypothetical protein 0.0074 0.1016 0.1318
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0074 0.1016 0.1364
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0015 0.0134 0.0134
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0033 0.0404 0.0417
Echinococcus multilocularis survival motor neuron protein 1 0.0229 0.3364 0.3347
Echinococcus multilocularis solute carrier family 22 0.0015 0.0134 0.0109
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0074 0.1016 0.0994
Schistosoma mansoni lysyl-tRNA synthetase 0.0024 0.0268 0.0244
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0074 0.1016 0.0994
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0134 0.0173
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0032 0.0393 0.0369
Onchocerca volvulus 0.0016 0.015 0.0268
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0432 0.0949
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0074 0.1016 0.1282
Schistosoma mansoni protein kinase 0.0033 0.0404 0.0379
Onchocerca volvulus 0.0016 0.015 0.0268
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0016 0.015 0.0277
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0033 0.0404 0.0549
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0033 0.0404 0.0549
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0032 0.0393 0.101
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.1016 0.1282
Mycobacterium ulcerans lipase LipD 0.0035 0.0432 0.1567
Schistosoma mansoni hypothetical protein 0.0108 0.1534 0.1512
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0517 0.7714 1
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0074 0.1016 0.1364
Loa Loa (eye worm) hypothetical protein 0.0015 0.0134 0.0232
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.001 0.0054 0.0029
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0074 0.1016 0.0994
Echinococcus granulosus FTZ F1 alpha 0.001 0.0054 0.0029
Toxoplasma gondii hypothetical protein 0.0161 0.2337 0.3407
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0517 0.7714 1
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0432 0.0559
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0134 0.0173
Giardia lamblia Lysyl-tRNA synthetase 0.0024 0.0268 0.0632
Echinococcus multilocularis geminin 0.0164 0.2384 0.2364
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0134 0.0173
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0033 0.0404 0.0379
Schistosoma mansoni thyroid hormone receptor 0.001 0.0054 0.0029
Plasmodium falciparum calcium-dependent protein kinase 1 0.0033 0.0404 0.0549
Entamoeba histolytica cysteine proteinase, putative 0.0016 0.015 0.3188
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.015 0.0194
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.002 0.0214 0.0254
Giardia lamblia Hypothetical protein 0.0074 0.1016 0.4145
Brugia malayi intermediate filament protein 0.0026 0.0299 0.0748
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0134 0.0173
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0134 0.0173
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0033 0.0404 0.0379
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0024 0.0268 0.0845
Echinococcus granulosus kinesin family 1 0.0201 0.2937 0.2919
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0008 0.0031 0.0006
Schistosoma mansoni sugar transporter 0.0015 0.0134 0.0109
Trypanosoma brucei glucose transporter 2A 0.0033 0.041 0.0493
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0134 0.0173
Echinococcus multilocularis synaptic vesicle 2 protein 0.0015 0.0134 0.0109
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0016 0.015 0.0125
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0095 0.007
Onchocerca volvulus 0.0015 0.0134 0.0224
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.015 0.0194
Plasmodium falciparum phosphodiesterase delta, putative 0.0074 0.1016 0.1452
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0356 0.5281 0.6834
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0517 0.7714 1
Onchocerca volvulus 0.0016 0.015 0.0268
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0074 0.1016 0.0994
Trypanosoma brucei glucose transporter, putative 0.0033 0.041 0.0493
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0202 0.2959 0.8146
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.001 0.0054 0.0009
Onchocerca volvulus Cathepsin L homolog 0.0016 0.015 0.0268
Schistosoma mansoni hypothetical protein 0.0047 0.0612 0.0588
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0083 0.1151 0.1129
Brugia malayi hypothetical protein 0.0015 0.0134 0.0286
Schistosoma mansoni hypothetical protein 0.0175 0.2543 0.2524
Schistosoma mansoni steroid hormone receptor ad4bp 0.001 0.0054 0.0029
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0134 0.0173
Loa Loa (eye worm) hypothetical protein 0.0026 0.0302 0.0703
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0038 0.0474 0.0577
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0038 0.0474 0.0577
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.018 0.0233
Trichomonas vaginalis CAMK family protein kinase 0.0033 0.0404 0.0523
Loa Loa (eye worm) major facilitator superfamily transporter 0.0015 0.0134 0.0232
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0134 0.0173
Onchocerca volvulus 0.0015 0.0134 0.0224
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.015 0.0194
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0095 0.007
Trypanosoma cruzi hexose transporter, putative 0.0033 0.041 0.0493
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0517 0.7714 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.015 0.0194
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0134 0.0173
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0235 0.3449 0.4471
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0018 0.018 0.0147
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0108 0.1534 0.1512
Schistosoma mansoni cpg binding protein 0.0029 0.0349 0.0324
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0517 0.7714 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0574 0.055
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.015 0.0194
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0033 0.0404 0.0379
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0134 0.0173
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0074 0.1016 0.1364
Loa Loa (eye worm) hypothetical protein 0.0011 0.0069 0.005
Loa Loa (eye worm) hypothetical protein 0.0026 0.0299 0.0696
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0074 0.1016 0.0994
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0033 0.0404 0.0379

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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