Detailed information for compound 1655415

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 998.202 | Formula: C46H71N13O10S
  • H donors: 11 H acceptors: 11 LogP: -1.32 Rotable bonds: 32
    Rule of 5 violations (Lipinski): 4
  • SMILES: CNCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1CSC([C@H]1C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@H](CC)C)C(=O)O)Cc1c[nH]cn1)(C)C)Cc1ccc(cc1)O)C(C)C)CCCN=C(N)N
  • InChi: 1S/C46H71N13O10S/c1-8-26(4)36(44(68)69)57-39(63)33-12-10-18-58(33)42(66)32(20-28-21-50-23-52-28)55-41(65)37-46(5,6)70-24-59(37)43(67)31(19-27-13-15-29(60)16-14-27)54-40(64)35(25(2)3)56-38(62)30(53-34(61)22-49-7)11-9-17-51-45(47)48/h13-16,21,23,25-26,30-33,35-37,49,60H,8-12,17-20,22,24H2,1-7H3,(H,50,52)(H,53,61)(H,54,64)(H,55,65)(H,56,62)(H,57,63)(H,68,69)(H4,47,48,51)/t26-,30-,31-,32-,33-,35-,36-,37+/m0/s1
  • InChiKey: LTQDQCLZIXJVML-DIVSHUKOSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0266 0.0402 0.1141
Onchocerca volvulus 0.0075 0.0088 0.3704
Schistosoma mansoni caspase-7 (C14 family) 0.026 0.0392 0.1207
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0071 0.008 0.0226
Mycobacterium ulcerans hypothetical protein 0.0041 0.0031 1
Loa Loa (eye worm) transcription factor SMAD2 0.0126 0.017 0.0483
Mycobacterium ulcerans hypothetical protein 0.0041 0.0031 1
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0081 0.0097 0.0276
Echinococcus granulosus mitogen activated protein kinase 11 0.2154 0.3526 0.3518
Loa Loa (eye worm) cytochrome P450 family protein 0.0051 0.0048 0.0135
Echinococcus multilocularis hyperpolarization activated cyclic 0.0071 0.008 0.0068
Trypanosoma cruzi target of rapamycin kinase 3 0.0423 0.0662 0.1878
Trypanosoma brucei SLACS reverse transcriptase, putative 0.0035 0.002 0.0057
Trichomonas vaginalis ribonuclease H1, putative 0.0153 0.0216 0.3053
Leishmania major hypothetical protein, unknown function 0.0071 0.008 0.0221
Trypanosoma cruzi polo-like protein kinase, putative 0.0112 0.0149 0.0422
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0081 0.0097 0.0085
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0071 0.008 0.3332
Echinococcus granulosus sodium leak channel non selective protein 0.0071 0.008 0.0068
Onchocerca volvulus 0.0081 0.0097 0.4167
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0071 0.008 0.0068
Schistosoma mansoni voltage-gated potassium channel 0.0075 0.0088 0.0246
Echinococcus granulosus sodium channel protein 0.0152 0.0214 0.0202
Brugia malayi ion channel NompC 0.0071 0.008 0.0226
Loa Loa (eye worm) hypothetical protein 0.0071 0.008 0.0226
Loa Loa (eye worm) hypothetical protein 0.0376 0.0584 0.1658
Schistosoma mansoni voltage-gated potassium channel 0.0071 0.008 0.0222
Plasmodium falciparum phosphatidylinositol 4-kinase 0.0081 0.0097 0.6221
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0052 0.0049 0.014
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0081 0.0097 0.1056
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0066 0.0072 0.0812
Echinococcus granulosus BTB:POZ domain containing protein 0.0075 0.0088 0.0076
Echinococcus multilocularis ribonuclease H1 0.0153 0.0216 0.0204
Schistosoma mansoni caspase-7 (C14 family) 0.0156 0.022 0.0665
Echinococcus multilocularis sodium:myo inositol cotransporter 0.0041 0.0031 0.0019
Brugia malayi Pao retrotransposon peptidase family protein 0.0035 0.002 0.0057
Echinococcus granulosus transient receptor potential cation channel 0.0071 0.008 0.0068
Loa Loa (eye worm) hypothetical protein 0.0071 0.008 0.0226
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0081 0.0097 0.1384
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0081 0.0097 0.0276
Loa Loa (eye worm) hypothetical protein 0.0146 0.0204 0.058
Brugia malayi reverse transcriptase 0.0035 0.002 0.0057
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0081 0.0097 0.0277
Leishmania major hypothetical protein, unknown function 0.0081 0.0097 0.027
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0071 0.008 0.0068
Trichomonas vaginalis PIKK family atypical protein kinase 0.0423 0.0662 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0423 0.0662 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0423 0.0662 1
Schistosoma mansoni hypothetical protein 0.0081 0.0097 0.0277
Onchocerca volvulus Ribonuclease H1 homolog 0.0153 0.0216 0.9801
Trichomonas vaginalis PIKK family atypical protein kinase 0.0423 0.0662 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.0022 0.0063
Echinococcus multilocularis potassium voltage gated channel protein 0.0146 0.0204 0.0193
Brugia malayi K+ channel tetramerisation domain containing protein 0.0075 0.0088 0.0248
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0081 0.0097 0.0277
Schistosoma mansoni voltage-gated potassium channel 0.0075 0.0088 0.0246
Brugia malayi Pao retrotransposon peptidase family protein 0.0035 0.002 0.0057
Echinococcus granulosus c-Jun N-terminal kinases 0.1217 0.1976 0.1966
Brugia malayi Pao retrotransposon peptidase family protein 0.0035 0.002 0.0057
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0071 0.008 0.0222
Trichomonas vaginalis conserved hypothetical protein 0.0266 0.0402 0.5952
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0115 0.0152 0.2224
Schistosoma mansoni 60S ribosomal protein L21 0.0071 0.008 0.0222
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0112 0.0149 0.0137
Loa Loa (eye worm) hypothetical protein 0.0071 0.008 0.0226
Schistosoma mansoni voltage-gated potassium channel 0.0146 0.0204 0.0615
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0071 0.008 0.0222
Brugia malayi serine/threonine-protein kinase plk-2 0.0112 0.0149 0.0422
Loa Loa (eye worm) phosphatidylinositol 3 0.0081 0.0097 0.0276
Echinococcus multilocularis BTB:POZ domain containing protein 0.0075 0.0088 0.0076
Schistosoma mansoni voltage-gated potassium channel 0.0071 0.008 0.0222
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0146 0.0204 0.0193
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0081 0.0097 0.0085
Plasmodium falciparum kelch protein K13 0.0075 0.0088 0.5551
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0071 0.008 0.0226
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0423 0.0662 0.1878
Toxoplasma gondii transporter, cation channel family protein 0.0071 0.008 0.1115
Brugia malayi FAT domain containing protein 0.0184 0.0268 0.0759
Brugia malayi Pao retrotransposon peptidase family protein 0.0035 0.002 0.0057
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0071 0.008 0.0068
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0071 0.008 0.0068
Echinococcus granulosus TRP transient receptor potential channel 0.0071 0.008 0.0068
Echinococcus granulosus RNA directed DNA polymerase reverse transcriptase 0.0035 0.002 0.0008
Brugia malayi hypothetical protein 0.0027 0.0007 0.0019
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0238 0.0357 0.1013
Trypanosoma brucei btb/poz domain containing protein, putative 0.0075 0.0088 0.0248
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.2154 0.3526 1
Echinococcus granulosus sodium:glucose cotransporter 0.0041 0.0031 0.0019
Schistosoma mansoni voltage-gated cation channel 0.0071 0.008 0.0222
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0081 0.0097 0.0277
Toxoplasma gondii K+ channel tetramerisation domain-containing protein 0.0075 0.0088 0.1235
Trypanosoma cruzi metacaspase 5, putative 0.0115 0.0152 0.0432
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0071 0.008 0.0068
Entamoeba histolytica CAAX prenyl protease family 0.0199 0.0292 0.4134
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0081 0.0097 0.0085
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0149 0.021 0.0198
Brugia malayi Transient-receptor-potential like protein 0.0071 0.008 0.0226
Leishmania major phosphatidylinositol kinase related protein, putative 0.0081 0.0097 0.027
Echinococcus granulosus voltage dependent calcium channel 0.0071 0.008 0.0068
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0146 0.0204 0.0193
Trypanosoma cruzi CAAX prenyl protease 2, putative 0.0199 0.0292 0.0827
Echinococcus granulosus transient receptor potential cation channel 0.0071 0.008 0.0068
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0115 0.0152 0.0451
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0071 0.008 0.0068
Onchocerca volvulus 0.0075 0.0088 0.3704
Brugia malayi Zinc knuckle family protein 0.0035 0.002 0.0057
Echinococcus multilocularis sodium leak channel non selective protein 0.0071 0.008 0.0068
Loa Loa (eye worm) phosphatidylinositol 3 0.0081 0.0097 0.0276
Loa Loa (eye worm) hypothetical protein 0.0156 0.022 0.0625
Loa Loa (eye worm) hypothetical protein 0.0071 0.008 0.0226
Loa Loa (eye worm) K+ channel tetramerisation domain-containing protein 0.0075 0.0088 0.0248
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.2154 0.3526 0.9772
Loa Loa (eye worm) voltage-dependent calcium channel 0.0071 0.008 0.0226
Trichomonas vaginalis PIKK family atypical protein kinase 0.0423 0.0662 1
Trichomonas vaginalis CAMK family protein kinase 0.0112 0.0149 0.2003
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0238 0.0357 0.5171
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0071 0.008 0.0226
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0071 0.008 0.1115
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0081 0.0097 0.0276
Trypanosoma brucei Endonuclease-reverse transcriptase/Reverse transcriptase (RNA-dependent DNA polymerase), putative 0.0035 0.002 0.0057
Loa Loa (eye worm) hypothetical protein 0.0075 0.0088 0.0248
Brugia malayi Calcitonin receptor-like protein seb-1 0.0052 0.0049 0.014
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0071 0.008 0.0222
Schistosoma mansoni family U48 unassigned peptidase (U48 family) 0.0199 0.0292 0.089
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0071 0.008 0.0068
Brugia malayi K+ channel tetramerisation domain containing protein 0.0075 0.0088 0.0248
Loa Loa (eye worm) hypothetical protein 0.1733 0.2828 0.8022
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0238 0.0357 0.0345
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0115 0.0152 0.206
Echinococcus multilocularis voltage gated potassium channel 0.0146 0.0204 0.0193
Echinococcus multilocularis voltage dependent calcium channel 0.0071 0.008 0.0068
Trypanosoma brucei btb/poz domain containing protein, putative 0.0075 0.0088 0.0248
Giardia lamblia Phosphatidylinositol 4-kinase 0.0081 0.0097 0.1202
Trichomonas vaginalis conserved hypothetical protein 0.0115 0.0152 0.206
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.0081 0.0097 0.0276
Treponema pallidum ribonuclease H (rnhA) 0.0153 0.0216 1
Trypanosoma brucei ribonuclease H1 0.0153 0.0216 0.0613
Echinococcus multilocularis potassium voltage gated channel protein 0.1733 0.2828 0.282
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0071 0.008 0.0068
Schistosoma mansoni voltage-gated potassium channel 0.0071 0.008 0.0222
Schistosoma mansoni voltage-gated potassium channel 0.0071 0.008 0.0222
Schistosoma mansoni caspase-3 (C14 family) 0.026 0.0392 0.1207
Trypanosoma cruzi hypothetical protein 0.0066 0.0072 0.0205
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0035 0.002 0.0008
Trypanosoma brucei unspecified product 0.0188 0.0274 0.0776
Schistosoma mansoni cpg binding protein 0.003 0.0012 0.0008
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0071 0.008 0.0222
Echinococcus multilocularis caspase 8 0.0115 0.0152 0.014
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0115 0.0152 0.0432
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.0081 0.0097 0.0276
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0071 0.008 0.0226
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0115 0.0152 0.206
Echinococcus granulosus serine protein kinase ATM 0.0238 0.0357 0.0345
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0071 0.008 0.0226
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0081 0.0097 0.1202
Trichomonas vaginalis CAMK family protein kinase 0.0061 0.0063 0.0674
Echinococcus granulosus RNA directed DNA polymerase reverse transcriptase 0.0035 0.002 0.0008
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0081 0.0097 0.1202
Onchocerca volvulus 0.0075 0.0088 0.3704
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0146 0.0204 0.0193
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.6069 1 1
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0081 0.0097 0.0277
Trypanosoma brucei metacaspase 0.0115 0.0152 0.0432
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0071 0.008 0.0226
Onchocerca volvulus 0.0041 0.0031 0.1009
Schistosoma mansoni kinase 0.0062 0.0066 0.0177
Echinococcus granulosus apoptotic protease activating factor 1 0.0041 0.0031 0.0019
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0423 0.0662 0.1835
Echinococcus multilocularis two pore calcium channel protein 2 0.0071 0.008 0.0068
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0071 0.008 0.0222
Trypanosoma brucei RNA helicase, putative 0.1946 0.3181 0.9021
Loa Loa (eye worm) hypothetical protein 0.0071 0.008 0.0226
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0081 0.0097 0.1202
Loa Loa (eye worm) K+ channel tetramerisation domain-containing protein 0.0075 0.0088 0.0248
Loa Loa (eye worm) hypothetical protein 0.0071 0.008 0.0226
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0423 0.0662 0.1878
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0071 0.008 0.0068
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0081 0.0097 0.1384
Echinococcus granulosus traf and tnf receptor associated protein 0.0353 0.0547 0.0535
Echinococcus multilocularis transient receptor potential cation channel 0.0071 0.008 0.0068
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0007 0.0019
Trypanosoma brucei metacaspase 5, putative 0.0115 0.0152 0.0432
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0081 0.0097 0.0085
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0081 0.0097 0.1384
Loa Loa (eye worm) hypothetical protein 0.0071 0.008 0.0226
Toxoplasma gondii target of rapamycin (TOR), putative 0.0423 0.0662 1
Toxoplasma gondii hypothetical protein 0.0071 0.008 0.1115
Schistosoma mansoni hypothetical protein 0.0041 0.0031 0.0067
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0423 0.0662 0.1878
Entamoeba histolytica hypothetical protein 0.0081 0.0097 0.1056
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0071 0.008 0.0068
Toxoplasma gondii hypothetical protein 0.0041 0.0031 0.0367
Plasmodium vivax K+ channel tetramerisation domain containing protein 0.0075 0.0088 0.5551
Plasmodium vivax protease, putative 0.0041 0.0031 0.1649
Entamoeba histolytica hypothetical protein 0.0238 0.0357 0.5171
Trichomonas vaginalis PIKK family atypical protein kinase 0.0423 0.0662 1
Brugia malayi Stress-activated protein kinase jnk-1 0.1217 0.1976 0.5605
Loa Loa (eye worm) potassium channel tetramerisation domain containing 5 0.0075 0.0088 0.0248
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0066 0.0072 0.0812
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0071 0.008 0.0068
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0071 0.008 0.0928
Brugia malayi RNase H family protein 0.0153 0.0216 0.0613
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.0041 0.0031 0.0019
Toxoplasma gondii hypothetical protein 0.0071 0.008 0.1115
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0115 0.0152 0.206
Trichomonas vaginalis conserved hypothetical protein 0.0115 0.0152 0.206
Loa Loa (eye worm) hypothetical protein 0.0081 0.0097 0.0276
Schistosoma mansoni voltage-gated potassium channel 0.0146 0.0204 0.0615
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0081 0.0097 0.0276
Brugia malayi reverse transcriptase 0.0035 0.002 0.0057
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0035 0.002 0.0008
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0081 0.0097 0.1202
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0081 0.0097 0.1202
Trypanosoma brucei potassium voltage-gated channel, putative 0.0075 0.0088 0.0248
Loa Loa (eye worm) hypothetical protein 0.0071 0.008 0.0226
Trichomonas vaginalis conserved hypothetical protein 0.0115 0.0152 0.206
Trypanosoma cruzi btb/poz domain containing protein, putative 0.0075 0.0088 0.0248
Schistosoma mansoni edp1-related 0.0075 0.0088 0.0246
Loa Loa (eye worm) Kv4.2 voltage-gated potassium channel 0.0075 0.0088 0.0248
Brugia malayi hypothetical protein 0.0071 0.008 0.0226
Brugia malayi P38 map kinase family protein 2 0.2154 0.3526 1
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0081 0.0097 0.1202
Brugia malayi Pao retrotransposon peptidase family protein 0.0035 0.002 0.0057
Trichomonas vaginalis Sentrin-specific protease, putative 0.0066 0.0072 0.0812
Echinococcus multilocularis transient receptor potential cation channel 0.0071 0.008 0.0068
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0081 0.0097 0.0276
Brugia malayi reverse transcriptase 0.0035 0.002 0.0057
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.2154 0.3526 1
Loa Loa (eye worm) potassium channel tetramerisation domain containing 3 0.0075 0.0088 0.0248
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0157 0.0223 0.0631
Trichomonas vaginalis CAMK family protein kinase 0.0112 0.0149 0.2003
Echinococcus granulosus potassium large conductance calcium activated 0.0071 0.008 0.0068
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0081 0.0097 0.0276
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0081 0.0097 0.0276
Plasmodium vivax hypothetical protein, conserved 0.0081 0.0097 0.6221
Trypanosoma brucei polo-like protein kinase 0.0112 0.0149 0.0422
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0081 0.0097 0.0085
Echinococcus granulosus potassium voltage gated channel protein 0.0146 0.0204 0.0193
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0071 0.008 0.0226
Brugia malayi CXXC zinc finger family protein 0.0028 0.0009 0.0027
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.0081 0.0097 0.1056
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0071 0.008 0.0226
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0149 0.021 0.0631
Echinococcus granulosus calcium activated potassium channel 0.0081 0.0097 0.0085
Echinococcus multilocularis potassium voltage gated channel protein 0.0146 0.0204 0.0193
Onchocerca volvulus 0.0071 0.008 0.3332
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0071 0.008 0.0928
Onchocerca volvulus 0.0035 0.002 0.0511
Brugia malayi Pao retrotransposon peptidase family protein 0.0035 0.002 0.0057
Echinococcus granulosus two pore calcium channel protein 1 0.0071 0.008 0.0068
Leishmania major hypothetical protein, conserved 0.0075 0.0088 0.0243
Echinococcus multilocularis traf and tnf receptor associated protein 0.0353 0.0547 0.0535
Echinococcus multilocularis mitogen activated protein kinase 11 0.2154 0.3526 0.3518
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0423 0.0662 0.0651
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0071 0.008 0.0222
Trichomonas vaginalis PIKK family atypical protein kinase 0.0238 0.0357 0.525
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0081 0.0097 0.0276
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0081 0.0097 0.1056
Echinococcus granulosus voltage dependent calcium channel 0.0071 0.008 0.0068
Plasmodium falciparum protease, putative 0.0041 0.0031 0.1649
Brugia malayi K+ channel tetramerisation domain containing protein 0.0075 0.0088 0.0248
Loa Loa (eye worm) hypothetical protein 0.0071 0.008 0.0226
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0423 0.0662 0.1878
Trichomonas vaginalis conserved hypothetical protein 0.0115 0.0152 0.206
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0238 0.0357 0.1013
Schistosoma mansoni inositol transporter 0.0041 0.0031 0.0069
Leishmania major hypothetical protein, conserved 0.0075 0.0088 0.0243
Loa Loa (eye worm) hypothetical protein 0.0071 0.008 0.0226
Brugia malayi Cytochrome P450 family protein 0.0051 0.0048 0.0135
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0009 0.0027
Schistosoma mansoni serine/threonine protein kinase 0.0045 0.0038 0.0089
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.0081 0.0097 0.0085
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0081 0.0097 0.1202
Trichomonas vaginalis PIKK family atypical protein kinase 0.0423 0.0662 1
Echinococcus granulosus RNA directed DNA polymerase reverse transcriptase 0.0035 0.002 0.0008
Trichomonas vaginalis CAMK family protein kinase 0.0112 0.0149 0.2003
Entamoeba histolytica serine/threonine protein kinase, putative 0.0112 0.0149 0.187
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0081 0.0097 0.0276
Giardia lamblia Hypothetical protein 0.0081 0.0097 0.1202
Leishmania major potassium voltage-gated channel, putative 0.0075 0.0088 0.0243
Trichomonas vaginalis CAMK family protein kinase 0.0112 0.0149 0.2003
Echinococcus multilocularis shaker cognate 0.0146 0.0204 0.0193
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0423 0.0662 0.1878
Echinococcus multilocularis tumor protein p63 0.0332 0.0512 0.05
Loa Loa (eye worm) calcium channel 0.0071 0.008 0.0226
Trypanosoma cruzi metacaspase 5, putative 0.0115 0.0152 0.0432
Schistosoma mansoni voltage-gated potassium channel 0.0071 0.008 0.0222
Trichomonas vaginalis PIKK family atypical protein kinase 0.0238 0.0357 0.525
Echinococcus granulosus RNA directed DNA polymerase reverse transcriptase 0.0035 0.002 0.0008
Onchocerca volvulus 0.0049 0.0043 0.1597
Trichomonas vaginalis PIKK family atypical protein kinase 0.0423 0.0662 1
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.1217 0.1976 0.5605
Trichomonas vaginalis PIKK family atypical protein kinase 0.0423 0.0662 1
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0343 0.053 0.7981
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0149 0.021 0.0594
Loa Loa (eye worm) hypothetical protein 0.0199 0.0292 0.0827
Mycobacterium leprae conserved hypothetical protein 0.0081 0.0097 0.5
Schistosoma mansoni voltage-gated potassium channel 0.1733 0.2828 0.8889
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0081 0.0097 0.0276
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0238 0.0357 0.1013
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0071 0.008 0.0068
Loa Loa (eye worm) hypothetical protein 0.0071 0.008 0.0226
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0071 0.008 0.3332
Schistosoma mansoni hypothetical protein 0.1946 0.3181 1
Schistosoma mansoni family U48 unassigned peptidase (U48 family) 0.0199 0.0292 0.089
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0071 0.008 0.0222
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0081 0.0097 0.0276
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0146 0.0204 0.0193
Toxoplasma gondii CAAX amino terminal protease family protein 0.0041 0.0031 0.0367
Loa Loa (eye worm) hypothetical protein 0.0071 0.008 0.0226
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0035 0.002 0.0008
Trypanosoma brucei ingi protein (ORF1) 0.0188 0.0274 0.0776
Brugia malayi Pao retrotransposon peptidase family protein 0.0035 0.002 0.0057
Echinococcus multilocularis caspase 0.026 0.0392 0.0381
Loa Loa (eye worm) phosphatidylinositol 3 0.0081 0.0097 0.0276
Trichomonas vaginalis conserved hypothetical protein 0.0157 0.0223 0.3154
Trichomonas vaginalis CAMK family protein kinase 0.0061 0.0063 0.0674
Echinococcus multilocularis voltage gated potassium channel 0.0071 0.008 0.0068
Trichomonas vaginalis PIKK family atypical protein kinase 0.0238 0.0357 0.525
Schistosoma mansoni scy1(yeast) protein kinase-like 0.0035 0.002 0.0034
Echinococcus granulosus caspase 2 0.0156 0.022 0.0209
Trichomonas vaginalis PIKK family atypical protein kinase 0.0423 0.0662 1
Schistosoma mansoni voltage-gated potassium channel 0.0146 0.0204 0.0615
Schistosoma mansoni voltage-gated potassium channel 0.0071 0.008 0.0222
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0071 0.008 0.0222
Schistosoma mansoni vesicular amine transporter 0.0146 0.0204 0.0615
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.026 0.0392 0.0381
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0081 0.0097 0.0276
Trichomonas vaginalis PIKK family atypical protein kinase 0.0423 0.0662 1
Trypanosoma brucei PAB1-binding protein , putative 0.0027 0.0007 0.0019
Schistosoma mansoni high-affinity choline transporter 0.0376 0.0584 0.1813
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0081 0.0097 0.6221
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0081 0.0097 0.0276
Schistosoma mansoni phosphoglucomutase 0.0153 0.0216 0.0652
Trypanosoma cruzi potassium voltage-gated channel 0.0075 0.0088 0.0248
Trypanosoma cruzi metacaspase, putative 0.0115 0.0152 0.0432
Loa Loa (eye worm) hypothetical protein 0.0041 0.0031 0.0087
Trypanosoma cruzi btb/poz domain containing protein, putative 0.0075 0.0088 0.0248
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0423 0.0662 0.0651
Mycobacterium tuberculosis Probable conserved integral membrane protein 0.0041 0.0031 0.1359
Trichomonas vaginalis PIKK family atypical protein kinase 0.0266 0.0402 0.5952
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.0081 0.0097 0.0085
Trypanosoma cruzi hypothetical protein, conserved 0.2123 0.3473 0.9851
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0081 0.0097 0.1384
Echinococcus multilocularis transfer RNA-Gly 0.0146 0.0204 0.0193
Plasmodium falciparum metacaspase 1 0.0115 0.0152 1
Echinococcus multilocularis 0.0081 0.0097 0.0085
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0071 0.008 0.0222
Echinococcus multilocularis mitogen activated protein kinase 14 0.2154 0.3526 0.3518
Echinococcus granulosus transient receptor potential cation channel 0.0071 0.008 0.0068
Trichomonas vaginalis PIKK family atypical protein kinase 0.0423 0.0662 1
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0423 0.0662 1
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0423 0.0662 0.1835
Schistosoma mansoni phosphoglucomutase 0.0153 0.0216 0.0652
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0112 0.0149 0.0422
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.0081 0.0097 0.6221
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0081 0.0097 0.1056
Trypanosoma cruzi metacaspase, putative 0.0115 0.0152 0.0432
Chlamydia trachomatis hypothetical protein 0.0041 0.0031 0.5
Loa Loa (eye worm) hypothetical protein 0.0115 0.0152 0.0432
Trypanosoma brucei Metacaspase-4 0.0115 0.0152 0.0432
Echinococcus multilocularis transient receptor potential cation channel 0.0071 0.008 0.0068
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0184 0.0268 0.0256
Mycobacterium tuberculosis Probable integral membrane protein 0.0041 0.0031 0.1359
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0238 0.0357 0.1097
Echinococcus granulosus potassium voltage gated channel protein 0.0146 0.0204 0.0193
Echinococcus multilocularis calcium activated potassium channel 0.0081 0.0097 0.0085
Trichomonas vaginalis PIKK family atypical protein kinase 0.0081 0.0097 0.1202
Echinococcus multilocularis hyperpolarization activated cyclic 0.0071 0.008 0.0068
Echinococcus multilocularis ryanodine receptor 44f 0.0071 0.008 0.0068
Trichomonas vaginalis PIKK family atypical protein kinase 0.0423 0.0662 1
Loa Loa (eye worm) Ulp1 protease 0.0066 0.0072 0.0205
Echinococcus multilocularis caspase 3 0.0145 0.0203 0.0191
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0081 0.0097 0.0085
Brugia malayi Pao retrotransposon peptidase family protein 0.0035 0.002 0.0057
Loa Loa (eye worm) hypothetical protein 0.0071 0.008 0.0226
Trichomonas vaginalis PIKK family atypical protein kinase 0.0423 0.0662 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0149 0.021 0.0631
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0071 0.008 0.0068
Trichomonas vaginalis conserved hypothetical protein 0.0115 0.0152 0.206
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0081 0.0097 0.027
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0115 0.0152 0.206
Schistosoma mansoni voltage-gated potassium channel 0.0146 0.0204 0.0615
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0081 0.0097 0.1202
Brugia malayi Pao retrotransposon peptidase family protein 0.0035 0.002 0.0057
Schistosoma mansoni sodium/solute symporter 0.0041 0.0031 0.0069
Echinococcus granulosus sodium:glucose cotransporter 2 0.0041 0.0031 0.0019
Echinococcus granulosus shaker cognate 0.0146 0.0204 0.0193
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.0041 0.0031 0.0377
Loa Loa (eye worm) hypothetical protein 0.0081 0.0097 0.0276
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0071 0.008 0.0222
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0007 0.0019
Trichomonas vaginalis PIKK family atypical protein kinase 0.0423 0.0662 1
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0071 0.008 0.0068
Trichomonas vaginalis PIKK family atypical protein kinase 0.0423 0.0662 1
Brugia malayi Pao retrotransposon peptidase family protein 0.0035 0.002 0.0057
Onchocerca volvulus 0.0035 0.002 0.051
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0149 0.021 0.0198
Trypanosoma cruzi metacaspase, putative 0.0115 0.0152 0.0432
Toxoplasma gondii ribonuclease HI protein 0.0153 0.0216 0.3197
Loa Loa (eye worm) hypothetical protein 0.0071 0.008 0.0226
Echinococcus multilocularis short transient receptor potential channel 6 0.0071 0.008 0.0068
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0071 0.008 0.0068
Echinococcus multilocularis CAAX prenyl protease 2 0.0199 0.0292 0.028
Brugia malayi CAAX amino terminal protease family protein 0.0199 0.0292 0.0827
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0081 0.0097 0.1202
Trypanosoma brucei btb/poz domain containing protein, putative 0.0075 0.0088 0.0248
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0071 0.008 0.0222
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0184 0.0268 0.0256
Echinococcus multilocularis c Jun NH2 terminal kinase 0.1217 0.1976 0.1966
Leishmania major hypothetical protein, conserved 0.0075 0.0088 0.0243
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0423 0.0662 0.1878
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0149 0.021 0.0631
Trichomonas vaginalis PIKK family atypical protein kinase 0.0423 0.0662 1
Echinococcus granulosus voltage gated potassium channel 0.0146 0.0204 0.0193
Loa Loa (eye worm) hypothetical protein 0.0027 0.0007 0.0019
Schistosoma mansoni hypothetical protein 0.0071 0.008 0.0222
Trichomonas vaginalis PIKK family atypical protein kinase 0.0423 0.0662 1
Onchocerca volvulus Serine\/threonine kinase homolog 0.0112 0.0149 0.6606
Leishmania major phosphatidylinositol kinase, putative 0.0081 0.0097 0.027
Echinococcus multilocularis dnaJ subfamily B 0.0402 0.0627 0.0616
Loa Loa (eye worm) hypothetical protein 0.0071 0.008 0.0226
Giardia lamblia Ribonuclease H 0.0153 0.0216 0.3053
Echinococcus granulosus caspase 0.026 0.0392 0.0381
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0071 0.008 0.0068
Echinococcus granulosus sodium:myo inositol cotransporter 0.0041 0.0031 0.0019
Trichomonas vaginalis PIKK family atypical protein kinase 0.0423 0.0662 1
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0071 0.008 0.0068
Schistosoma mansoni voltage-gated potassium channel 0.0075 0.0088 0.0246
Brugia malayi cation channel family protein 0.0071 0.008 0.0226
Schistosoma mansoni hypothetical protein 0.0035 0.002 0.0034
Echinococcus multilocularis mitogen activated protein kinase 14 0.2154 0.3526 0.3518
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0081 0.0097 0.1202
Leishmania major phosphatidylinositol 4-kinase, putative 0.0081 0.0097 0.027
Echinococcus granulosus KRAB A domain containing protein 0.0035 0.002 0.0008
Trypanosoma cruzi btb/poz domain containing protein, putative 0.0075 0.0088 0.0248
Leishmania major ribonuclease H1, putative 0.0153 0.0216 0.0599
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0071 0.008 0.0226
Brugia malayi RNase H family protein 0.0153 0.0216 0.0613
Schistosoma mansoni voltage-dependent calcium channel 0.0071 0.008 0.0222
Brugia malayi Sodium:solute symporter family protein 0.0041 0.0031 0.0089
Echinococcus granulosus potassium voltage gated channel subfamily A 0.1733 0.2828 0.282
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0423 0.0662 0.1835
Loa Loa (eye worm) voltage-gated potassium channel 0.0146 0.0204 0.058
Trichomonas vaginalis PIKK family atypical protein kinase 0.0238 0.0357 0.525
Schistosoma mansoni two-pore calcium channel 0.0071 0.008 0.0222
Echinococcus granulosus caspase 8 0.0115 0.0152 0.014
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0238 0.0357 0.0345
Trichomonas vaginalis PIKK family atypical protein kinase 0.0423 0.0662 1
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0081 0.0097 0.0276
Entamoeba histolytica hypothetical protein 0.0081 0.0097 0.1056
Brugia malayi voltage-dependent calcium channel 0.0071 0.008 0.0226
Brugia malayi Pao retrotransposon peptidase family protein 0.0035 0.002 0.0057
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0236 0.0353 0.1
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0071 0.008 0.0068
Brugia malayi hypothetical protein 0.0035 0.002 0.0057
Schistosoma mansoni protein kinase 0.0035 0.002 0.0034
Loa Loa (eye worm) hypothetical protein 0.0157 0.0223 0.0631
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0066 0.0072 0.0205
Trypanosoma brucei BTB/POZ domain/Regulator of chromosome condensation (RCC1) repeat, putative 0.0075 0.0088 0.0248
Schistosoma mansoni transient receptor potential channel 0.0071 0.008 0.0222
Loa Loa (eye worm) hypothetical protein 0.0071 0.008 0.0226
Loa Loa (eye worm) hypothetical protein 0.0071 0.008 0.0226
Trichomonas vaginalis PIKK family atypical protein kinase 0.0081 0.0097 0.1202
Schistosoma mansoni fkbp-rapamycin associated protein 0.0238 0.0357 0.1097
Trypanosoma brucei btb/poz domain containing protein, putative 0.0075 0.0088 0.0248
Loa Loa (eye worm) hypothetical protein 0.0041 0.0031 0.0089
Echinococcus multilocularis high affinity choline transporter 1 0.0376 0.0584 0.0573
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0081 0.0097 0.1202
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0081 0.0097 0.1202
Schistosoma mansoni voltage-gated potassium channel 0.0071 0.008 0.0222
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0081 0.0097 0.1056
Schistosoma mansoni ryanodine receptor related 0.0071 0.008 0.0222
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0071 0.008 0.0068
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0071 0.008 0.0068
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0081 0.0097 0.1384
Brugia malayi olfactory channel protein osm-9 0.0071 0.008 0.0226
Brugia malayi Cyclic-nucleotide gated cation channel 0.0071 0.008 0.0226
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0115 0.0152 0.206
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0071 0.008 0.0226
Loa Loa (eye worm) phosphatidylinositol 3 0.0423 0.0662 0.1878
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0066 0.0072 0.0198
Brugia malayi Pao retrotransposon peptidase family protein 0.0035 0.002 0.0057
Plasmodium falciparum metacaspase-like protein 0.0115 0.0152 1
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0115 0.0152 0.206
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0071 0.008 0.0222
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0035 0.002 0.0008
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0081 0.0097 0.0276
Echinococcus granulosus mitogen activated protein kinase 14 0.2154 0.3526 0.3518
Schistosoma mansoni transient receptor potential channel 4 0.0071 0.008 0.0222
Brugia malayi Pao retrotransposon peptidase family protein 0.0035 0.002 0.0057
Loa Loa (eye worm) hypothetical protein 0.0075 0.0088 0.0248
Onchocerca volvulus 0.0081 0.0097 0.4167
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.002 0.0057
Echinococcus multilocularis two pore calcium channel protein 1 0.0071 0.008 0.0068
Echinococcus multilocularis transient receptor potential cation channel 0.0071 0.008 0.0068
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0423 0.0662 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0157 0.0223 0.3154
Trichomonas vaginalis PIKK family atypical protein kinase 0.0423 0.0662 1
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0115 0.0152 0.2224
Echinococcus multilocularis potassium large conductance calcium activated 0.0071 0.008 0.0068
Schistosoma mansoni cpg binding protein 0.003 0.0012 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0423 0.0662 1
Loa Loa (eye worm) hypothetical protein 0.0184 0.0268 0.0759
Schistosoma mansoni calcium-activated potassium channel 0.0071 0.008 0.0222
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0081 0.0097 0.1056
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0238 0.0357 0.1013
Trichomonas vaginalis conserved hypothetical protein 0.0184 0.0268 0.3856
Brugia malayi follicle stimulating hormone receptor 0.0236 0.0353 0.1
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0115 0.0152 0.206
Echinococcus multilocularis sodium channel protein 0.0152 0.0214 0.0202
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0035 0.002 0.0008
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0423 0.0662 0.0651
Trichomonas vaginalis PIKK family atypical protein kinase 0.0423 0.0662 1
Echinococcus granulosus transient receptor potential cation channel 0.0071 0.008 0.0068
Trypanosoma cruzi btb/poz domain containing protein, putative 0.0075 0.0088 0.0248
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0115 0.0152 0.2224
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0423 0.0662 0.1878
Loa Loa (eye worm) hypothetical protein 0.0052 0.0049 0.014
Trypanosoma brucei metacaspase MCA3 0.0115 0.0152 0.0432
Echinococcus granulosus hyperpolarization activated cyclic 0.0071 0.008 0.0068
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0115 0.0152 0.206
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0152 0.0214 0.0592
Giardia lamblia Hypothetical protein 0.0199 0.0292 0.423
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0081 0.0097 0.1056
Echinococcus granulosus potassium voltage gated channel protein 0.1733 0.2828 0.282
Loa Loa (eye worm) ryanodine receptor 0.0071 0.008 0.0226
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0071 0.008 0.1115
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0423 0.0662 0.1835
Trichomonas vaginalis PIKK family atypical protein kinase 0.0423 0.0662 1
Plasmodium vivax hypothetical protein, conserved 0.0115 0.0152 1
Echinococcus multilocularis apoptotic protease activating factor 1 0.0041 0.0031 0.0019
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0071 0.008 0.0068
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0149 0.021 0.0198
Trichomonas vaginalis Clan U, family U48, CaaX prenyl peptidase 2-like 0.0199 0.0292 0.423
Mycobacterium tuberculosis Conserved hypothetical protein 0.0041 0.0031 0.1359
Schistosoma mansoni voltage-gated potassium channel 0.0146 0.0204 0.0615
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0423 0.0662 0.1878
Echinococcus multilocularis transient receptor potential gamma protein 0.0071 0.008 0.0068
Schistosoma mansoni hypothetical protein 0.0035 0.002 0.0034
Toxoplasma gondii transporter, cation channel family protein 0.0071 0.008 0.1115
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.1657 0.2703 0.2695
Echinococcus granulosus voltage gated potassium channel 0.0071 0.008 0.0068
Echinococcus granulosus transient receptor potential cation channel 0.0071 0.008 0.0068
Echinococcus multilocularis transient receptor potential cation channel 0.0071 0.008 0.0068
Echinococcus multilocularis transient receptor potential cation channel 0.0071 0.008 0.0068
Trichomonas vaginalis PIKK family atypical protein kinase 0.0238 0.0357 0.525
Giardia lamblia GTOR 0.0423 0.0662 1
Echinococcus granulosus CAAX prenyl protease 2 0.0199 0.0292 0.028
Trichomonas vaginalis PIKK family atypical protein kinase 0.0423 0.0662 1
Echinococcus granulosus hyperpolarization activated cyclic 0.0071 0.008 0.0068
Brugia malayi hypothetical protein 0.0035 0.002 0.0057
Brugia malayi hypothetical protein 0.0041 0.0031 0.0087
Brugia malayi mKIAA0176 protein 0.0075 0.0088 0.0248
Trichomonas vaginalis conserved hypothetical protein 0.0115 0.0152 0.206
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0146 0.0204 0.0193
Loa Loa (eye worm) phosphatidylinositol 3 0.0423 0.0662 0.1878
Plasmodium vivax hypothetical protein 0.0081 0.0097 0.6221
Schistosoma mansoni voltage-gated potassium channel 0.0071 0.008 0.0222
Echinococcus multilocularis short transient receptor potential channel 6 0.0071 0.008 0.0068
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0238 0.0357 0.1013
Trichomonas vaginalis PIKK family atypical protein kinase 0.0238 0.0357 0.525
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0071 0.008 0.0226
Mycobacterium tuberculosis Probable conserved integral membrane protein 0.0041 0.0031 0.1359
Echinococcus multilocularis BTB:POZ domain containing protein KCTD16 0.0075 0.0088 0.0076
Echinococcus multilocularis Zinc finger, PHD finger 0.0081 0.0097 0.0085
Echinococcus multilocularis potassium voltage gated channel protein 0.0071 0.008 0.0068
Echinococcus granulosus ribonuclease H1 0.0153 0.0216 0.0204
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0081 0.0097 0.6221
Trypanosoma brucei potassium voltage-gated channel, putative 0.0075 0.0088 0.0248
Loa Loa (eye worm) hypothetical protein 0.0049 0.0043 0.0122
Schistosoma mansoni voltage-gated potassium channel 0.0071 0.008 0.0222
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0071 0.008 0.0222
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0146 0.0204 0.058
Schistosoma mansoni voltage-gated potassium channel 0.1733 0.2828 0.8889
Loa Loa (eye worm) hypothetical protein 0.0071 0.008 0.0226
Schistosoma mansoni hypothetical protein 0.0184 0.0268 0.0814
Echinococcus multilocularis RNA directed DNA polymerase 0.0035 0.002 0.0008
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0081 0.0097 0.0277
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0035 0.002 0.0008
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0081 0.0097 0.0276
Loa Loa (eye worm) phosphatidylinositol 3 0.0081 0.0097 0.0276
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.2154 0.3526 1
Echinococcus multilocularis caspase 2 0.0156 0.022 0.0209
Leishmania major hypothetical protein, conserved 0.0071 0.008 0.0221
Toxoplasma gondii FATC domain-containing protein 0.0238 0.0357 0.5348
Echinococcus granulosus potassium voltage gated channel protein 0.0071 0.008 0.0068
Echinococcus granulosus dnaJ subfamily B 0.0402 0.0627 0.0616
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0081 0.0097 0.0276
Loa Loa (eye worm) phosphatidylinositol kinase 0.0081 0.0097 0.0276
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0149 0.021 0.0198
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0035 0.002 0.0008
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.1733 0.2828 0.8022
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0146 0.0204 0.058
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0071 0.008 0.0226
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0423 0.0662 0.0651
Brugia malayi Voltage-gated potassium channel, Shal-family (KCND, Kv4-like) alpha-subunit. C. elegans shl-1 ortholog 0.0075 0.0088 0.0248
Echinococcus granulosus hypothetical protein 0.0071 0.008 0.0068
Loa Loa (eye worm) K+ channel tetramerisation domain-containing protein 0.0075 0.0088 0.0248
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0081 0.0097 0.6221
Echinococcus multilocularis mitogen activated protein kinase 11 0.2154 0.3526 0.3518
Toxoplasma gondii transporter, cation channel family protein 0.0071 0.008 0.1115
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0071 0.008 0.0068
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0081 0.0097 0.0085
Loa Loa (eye worm) hypothetical protein 0.0071 0.008 0.0226
Schistosoma mansoni hypothetical protein 0.0036 0.0022 0.004
Trypanosoma cruzi ribonuclease H1, putative 0.0153 0.0216 0.0613
Trichomonas vaginalis PIKK family atypical protein kinase 0.0238 0.0357 0.525
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0081 0.0097 0.0277
Echinococcus multilocularis serine protein kinase ATM 0.0238 0.0357 0.0345
Brugia malayi latrophilin 2 splice variant baaae 0.0036 0.0022 0.0063
Trypanosoma brucei ingi protein (ORF1) 0.0188 0.0274 0.0776
Giardia lamblia Kinase, PLK 0.0112 0.0149 0.2003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0423 0.0662 1
Trypanosoma cruzi ribonuclease H1, putative 0.0153 0.0216 0.0613
Onchocerca volvulus 0.0075 0.0088 0.3704
Wolbachia endosymbiont of Brugia malayi ribonuclease HI 0.0153 0.0216 0.5
Onchocerca volvulus Telomerase reverse transcriptase homolog 0.0035 0.002 0.051
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0152 0.0214 0.0202
Leishmania major phosphatidylinositol 3-kinase, putative 0.0423 0.0662 0.1835
Schistosoma mansoni transient receptor potential channel 0.0071 0.008 0.0222
Echinococcus granulosus transient receptor potential cation channel 0.0071 0.008 0.0068
Trichomonas vaginalis CAMK family protein kinase 0.0112 0.0149 0.2003
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0348 0.0538 0.1526
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0035 0.002 0.0008
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0081 0.0097 0.0085
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0035 0.002 0.0008
Toxoplasma gondii kelch repeat and K+ channel tetramerisation domain containing protein 0.0075 0.0088 0.1235
Schistosoma mansoni inositol transporter 0.0041 0.0031 0.0069
Loa Loa (eye worm) hypothetical protein 0.0266 0.0402 0.1141
Trypanosoma cruzi btb/poz domain containing protein, putative 0.0075 0.0088 0.0248
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0146 0.0204 0.0193
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0071 0.008 0.0226
Trichomonas vaginalis CAMK family protein kinase 0.0112 0.0149 0.2003
Trypanosoma brucei CAAX amino terminal protease, putative 0.0199 0.0292 0.0827
Plasmodium vivax kelch protein K13, putative 0.0075 0.0088 0.5551
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0081 0.0097 0.0276
Schistosoma mansoni voltage-gated ion channel 0.0071 0.008 0.0222
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0071 0.008 0.0222
Echinococcus granulosus solute carrier family 5 0.0041 0.0031 0.0019
Trypanosoma cruzi potassium voltage-gated channel, putative 0.0075 0.0088 0.0248
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0081 0.0097 0.1056
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0112 0.0149 0.0412
Trypanosoma brucei metacaspase MCA2 0.0115 0.0152 0.0432
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0081 0.0097 0.1202
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0075 0.0088 0.0246
Leishmania major phosphatidylinositol 3-kinase, putative 0.0081 0.0097 0.027
Echinococcus granulosus caspase 3 0.0145 0.0203 0.0191
Trypanosoma cruzi hypothetical protein, conserved 0.0075 0.0088 0.0248
Entamoeba histolytica hypothetical protein 0.0081 0.0097 0.1056
Onchocerca volvulus Cell death protein 3 homolog 0.0156 0.022 1
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0071 0.008 0.0222
Brugia malayi Cell death protein 3 precursor 0.0156 0.022 0.0625
Trypanosoma cruzi peptidase with unknown catalytic mechanism (family U48) 0.0199 0.0292 0.0827
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0423 0.0662 0.2058
Loa Loa (eye worm) ion channel NompC 0.0071 0.008 0.0226
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0081 0.0097 0.0276
Echinococcus granulosus voltage gated hydrogen channel 1 0.0071 0.008 0.0068
Trichomonas vaginalis CAMK family protein kinase 0.0112 0.0149 0.2003
Leishmania major hypothetical protein, conserved 0.2204 0.3608 1
Trypanosoma cruzi metacaspase, putative 0.0115 0.0152 0.0432
Echinococcus granulosus transient receptor potential gamma protein 0.0071 0.008 0.0068
Leishmania major CAAX prenyl protease 2, putative,peptidase with unknown catalytic mechanism (family U48) 0.0199 0.0292 0.0808
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0071 0.008 0.0226
Loa Loa (eye worm) hypothetical protein 0.0075 0.0088 0.0248
Onchocerca volvulus 0.0075 0.0088 0.3704
Echinococcus multilocularis voltage dependent calcium channel 0.0071 0.008 0.0068
Brugia malayi Zinc knuckle family protein 0.0035 0.002 0.0057
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0081 0.0097 0.0276
Entamoeba histolytica protein kinase rad3, putative 0.0238 0.0357 0.5171
Schistosoma mansoni transient receptor potential channel 0.0071 0.008 0.0222
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0075 0.0088 0.5551
Trichomonas vaginalis PIKK family atypical protein kinase 0.0081 0.0097 0.1202
Loa Loa (eye worm) voltage-gated calcium channel 0.0071 0.008 0.0226
Mycobacterium tuberculosis Conserved hypothetical protein 0.0081 0.0097 1
Schistosoma mansoni serine/threonine protein kinase 0.0112 0.0149 0.0439
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0423 0.0662 0.1878
Brugia malayi K+ channel tetramerisation domain containing protein 0.0075 0.0088 0.0248
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0043 0.0106
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0423 0.0662 0.1878
Echinococcus granulosus two pore calcium channel protein 2 0.0071 0.008 0.0068
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0081 0.0097 0.0085
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0071 0.008 0.0226
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0353 0.0547 0.1551
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0112 0.0149 0.0137
Schistosoma mansoni voltage-gated potassium channel 0.0146 0.0204 0.0615
Echinococcus granulosus short transient receptor potential channel 6 0.0071 0.008 0.0068
Brugia malayi hypothetical protein 0.0035 0.002 0.0057
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0081 0.0097 0.1202
Loa Loa (eye worm) phosphatidylinositol 3 0.0081 0.0097 0.0276
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.0062 0.0165
Echinococcus granulosus ryanodine receptor 44f 0.0071 0.008 0.0068
Schistosoma mansoni potassium channel tetramerization domain-containing 0.0075 0.0088 0.0246
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0066 0.0072 0.0659
Echinococcus multilocularis sodium:glucose cotransporter 2 0.0041 0.0031 0.0019
Entamoeba histolytica hypothetical protein 0.0081 0.0097 0.1056
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0071 0.008 0.0226
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.0081 0.0097 0.6221
Schistosoma mansoni hypothetical protein 0.0402 0.0627 0.1948
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.2154 0.3526 1
Echinococcus multilocularis sentrin specific protease 8 0.0066 0.0072 0.006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0238 0.0357 0.525
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0423 0.0662 0.2058
Schistosoma mansoni voltage-gated potassium channel 0.0071 0.008 0.0222
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0081 0.0097 0.0277
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0071 0.008 0.0226
Trypanosoma brucei hypothetical protein, conserved 0.0188 0.0274 0.0776
Schistosoma mansoni phosphoglucomutase 0.0153 0.0216 0.0652
Echinococcus granulosus RNA directed DNA polymerase 0.0035 0.002 0.0008
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.0041 0.0031 0.0019
Trypanosoma cruzi btb/poz domain containing protein, putative 0.0075 0.0088 0.0248
Trypanosoma brucei SLACS retrotransposable element (part), putative 0.0035 0.002 0.0057
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0071 0.008 0.0222
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0071 0.008 0.0226
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0146 0.0204 0.0193
Trichomonas vaginalis PIKK family atypical protein kinase 0.0423 0.0662 1
Echinococcus granulosus tumor protein p63 0.0332 0.0512 0.05
Echinococcus granulosus high affinity choline transporter 1 0.0376 0.0584 0.0573
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0035 0.002 0.0008
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0081 0.0097 0.6221
Trypanosoma brucei retrotransposon hot spot protein 4 (RHS4), interrupted 0.0188 0.0274 0.0776
Trypanosoma cruzi polo-like protein kinase, putative 0.0112 0.0149 0.0422
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.026 0.0392 0.0381
Echinococcus granulosus sentrin specific protease 8 0.0066 0.0072 0.006
Brugia malayi Pao retrotransposon peptidase family protein 0.0035 0.002 0.0057
Toxoplasma gondii histone lysine methyltransferase SET1 0.0053 0.0051 0.0679
Loa Loa (eye worm) voltage-gated potassium channel 0.0071 0.008 0.0226
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0266 0.0402 0.6036
Loa Loa (eye worm) hypothetical protein 0.0238 0.0357 0.1013
Loa Loa (eye worm) MH2 domain-containing protein 0.0126 0.017 0.0483
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0149 0.021 0.0594
Leishmania major metacaspase, putative 0.0115 0.0152 0.0422
Echinococcus granulosus BTB:POZ domain containing protein KCTD16 0.0075 0.0088 0.0076
Mycobacterium ulcerans integral membrane protein 0.0041 0.0031 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0423 0.0662 1
Schistosoma mansoni serine/threonine protein kinase 0.1217 0.1976 0.6202
Loa Loa (eye worm) hypothetical protein 0.0071 0.008 0.0226
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0066 0.0072 0.0812
Brugia malayi MH2 domain containing protein 0.0126 0.017 0.0483
Brugia malayi RNase H family protein 0.0153 0.0216 0.0613
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0052 0.0049 0.014
Echinococcus multilocularis conserved hypothetical protein 0.0071 0.008 0.0068
Toxoplasma gondii hypothetical protein 0.0041 0.0031 0.0367
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0071 0.008 0.0222
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0081 0.0097 0.0085
Onchocerca volvulus 0.0041 0.0031 0.104
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0071 0.008 0.0068
Brugia malayi GH02984p 0.0376 0.0584 0.1658
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0071 0.008 0.0226
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0081 0.0097 0.1202
Brugia malayi cation channel family protein 0.0071 0.008 0.0226
Echinococcus granulosus potassium voltage gated channel protein 0.0071 0.008 0.0068
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0071 0.008 0.0068
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0081 0.0097 0.0276
Plasmodium vivax metacaspase 1, putative 0.0115 0.0152 1
Leishmania major hypothetical protein, conserved 0.0027 0.0007 0.0018
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0423 0.0662 0.1878
Echinococcus multilocularis solute carrier family 5 0.0041 0.0031 0.0019
Brugia malayi hypothetical protein 0.0035 0.002 0.0057
Echinococcus granulosus short transient receptor potential channel 6 0.0071 0.008 0.0068
Trichomonas vaginalis PIKK family atypical protein kinase 0.0423 0.0662 1
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0115 0.0152 0.206

Activities

Activity type Activity value Assay description Source Reference
Activity (functional) = 0 % In vitro agonist activity of compound towards angiotensin II like was measured in a rabbit aorta assay, activity expressed as relative to angiotensin II ChEMBL. 2913307
pA2 (functional) = 9 % In vitro antagonist activity of compound towards angiotensin II like was measured in rabbit aorta assay ChEMBL. 2913307

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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