Detailed information for compound 1735601

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 464.507 | Formula: C27H28O7
  • H donors: 2 H acceptors: 5 LogP: 4.98 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(=CCc1c(O)cc(c2c1O[C@@]13[C@@H]4C(=O)OC3(CC=C(C)C)C(=O)[C@@H]([C@@H]4C)C=C1C2=O)O)C
  • InChi: 1S/C27H28O7/c1-12(2)6-7-15-18(28)11-19(29)20-22(30)17-10-16-14(5)21-25(32)34-26(24(16)31,9-8-13(3)4)27(17,21)33-23(15)20/h6,8,10-11,14,16,21,28-29H,7,9H2,1-5H3/t14-,16+,21-,26?,27+/m0/s1
  • InChiKey: UCLJDAOAFDHFEA-XYBONBLRSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Phosphatidylcholine:ceramide cholinephosphotransferase 3 0.0024 0.0283 0.0318
Loa Loa (eye worm) hypothetical protein 0.0035 0.0504 0.0596
Loa Loa (eye worm) nuclear hormone receptor 0.001 0.0016 0.0019
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0189 0.0118
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.002 0.0222 0.0222
Loa Loa (eye worm) hypothetical protein 0.002 0.0222 0.0263
Trichomonas vaginalis inositol monophosphatase, putative 0.0037 0.0529 0.0453
Brugia malayi hypothetical protein 0.0071 0.1184 0.1385
Brugia malayi ecdysone receptor 0.001 0.0016 0.0003
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.0222 0.0263
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.0222 0.0263
Echinococcus granulosus GPCR family 2 0.0016 0.0135 0.0135
Brugia malayi Phosphatidylcholine:ceramide cholinephosphotransferase 2 0.0024 0.0283 0.0318
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0187 0.0115
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0135 0.0143
Loa Loa (eye worm) cytochrome P450 family protein 0.0023 0.0278 0.0329
Loa Loa (eye worm) hypothetical protein 0.0011 0.0038 0.0045
Loa Loa (eye worm) hypothetical protein 0.0011 0.0038 0.0045
Brugia malayi nuclear receptor NHR-67 0.001 0.0016 0.0003
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.002 0.0222 0.0222
Trypanosoma brucei sphingomyelin/ceramide phosphorylethanolamine synthase, bifunctional 0.0024 0.0283 0.0217
Echinococcus multilocularis katanin p60 ATPase containing subunit A1 0.0027 0.0356 0.0356
Loa Loa (eye worm) vesicle-fusing ATPase 0.0313 0.5795 0.685
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0222 0.0222
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.0222 0.0206
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.014 0.2505 0.2505
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0037 0.0529 1
Brugia malayi hypothetical protein 0.0011 0.0038 0.0029
Brugia malayi steroid hormone receptor 0.002 0.0222 0.0246
Schistosoma mansoni cpg binding protein 0.003 0.0404 0.0388
Mycobacterium tuberculosis Probable reductase 0.0085 0.1459 0.2362
Loa Loa (eye worm) hypothetical protein 0.001 0.0016 0.0019
Loa Loa (eye worm) hypothetical protein 0.001 0.0016 0.0019
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.0222 0.0263
Trypanosoma cruzi katanin, putative 0.0027 0.0356 0.0294
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0187 0.0183
Mycobacterium tuberculosis Probable oxidoreductase 0.0095 0.164 0.2673
Schistosoma mansoni cell division control protein 48 aaa family protein 0.0506 0.9477 0.9476
Echinococcus multilocularis transitional endoplasmic reticulum atpase 0.0534 1 1
Plasmodium falciparum vacuolar protein sorting-associated protein 4 0.0027 0.0356 0.0294
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.0222 0.0246
Echinococcus multilocularis inositol monophosphatase 1 0.0037 0.0529 0.0529
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0504 0.0453
Loa Loa (eye worm) hypothetical protein 0.0011 0.0038 0.0045
Plasmodium vivax cell division cycle protein 48 homologue, putative 0.0506 0.9477 1
Loa Loa (eye worm) hypothetical protein 0.0034 0.0486 0.0575
Loa Loa (eye worm) hypothetical protein 0.001 0.0016 0.0019
Schistosoma mansoni hypothetical protein 0.0016 0.0135 0.0119
Entamoeba histolytica hypothetical protein 0.0024 0.0283 0.0104
Trichomonas vaginalis AAA ATPase, putative 0.0027 0.0356 0.0279
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0504 0.0489
Schistosoma mansoni hypothetical protein 0.0171 0.3082 0.3071
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0135 0.0143
Plasmodium vivax cell division cycle ATPase, putative 0.0193 0.3514 0.3655
Loa Loa (eye worm) pigment dispersing factor receptor c 0.005 0.0789 0.0932
Loa Loa (eye worm) hypothetical protein 0.0035 0.0504 0.0596
Trypanosoma cruzi katanin, putative 0.0027 0.0356 0.0294
Trichomonas vaginalis esterase, putative 0.0035 0.0504 0.0428
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0222 0.0246
Leishmania major vacuolar protein sorting-associated protein 4 0.0027 0.0356 0.0294
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.002 0.0222 0.0222
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0013 0.008 0.0001
Trichomonas vaginalis proteasome-activating nucleotidase, putative 0.0126 0.2236 0.2174
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.014 0.2505 0.2493
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.001 0.0016 0.0003
Brugia malayi transitional endoplasmic reticulum ATPase TER94, putative 0.0221 0.4037 0.4763
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0071 0.1184 0.1184
Loa Loa (eye worm) hypothetical protein 0.0035 0.0504 0.0596
Echinococcus multilocularis thyroid hormone receptor alpha 0.002 0.0222 0.0222
Loa Loa (eye worm) hypothetical protein 0.0011 0.0038 0.0045
Leishmania major DNA polymerase eta, putative 0.0019 0.0189 0.0117
Onchocerca volvulus 0.002 0.0222 0.0206
Loa Loa (eye worm) hypothetical protein 0.001 0.0016 0.0019
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0189 0.0117
Trypanosoma brucei vesicular transport protein (CDC48 homologue), putative 0.0027 0.0356 0.0295
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0187 0.0183
Brugia malayi Phosphatidylcholine:ceramide cholinephosphotransferase 1 0.0453 0.8461 1
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0135 0.0135
Toxoplasma gondii katanin-like family protein 0.0027 0.0356 0.0279
Entamoeba histolytica hypothetical protein 0.0071 0.1184 0.1074
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0189 0.0188
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0187 0.0114
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0013 0.008 0.008
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0189 0.0117
Mycobacterium ulcerans hypothetical protein 0.0035 0.0504 0.0727
Trichomonas vaginalis skd/vacuolar sorting, putative 0.0027 0.0356 0.0279
Trichomonas vaginalis sphingomyelin synthetase, putative 0.0024 0.0283 0.0205
Echinococcus granulosus geminin 0.0171 0.3082 0.3082
Loa Loa (eye worm) glutathione reductase 0.0037 0.0546 0.0645
Mycobacterium tuberculosis Conserved protein 0.0035 0.0504 0.0727
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0187 0.0187
Trypanosoma cruzi vesicular transport protein (CDC48 homologue), putative 0.0027 0.0356 0.0294
Plasmodium falciparum glutathione reductase 0.0037 0.0546 0.0496
Toxoplasma gondii cell division protein CDC48CY 0.0534 1 1
Brugia malayi glutathione reductase 0.0037 0.0546 0.0629
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.005 0.0789 0.0917
Loa Loa (eye worm) hypothetical protein 0.0024 0.0283 0.0335
Schistosoma mansoni hypothetical protein 0.0027 0.0356 0.034
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0013 0.008 0.008
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0529 0.0478
Toxoplasma gondii ABC1 family protein 0.0035 0.0504 0.0428
Mycobacterium leprae Probable lipase LipE 0.0035 0.0504 0.0411
Schistosoma mansoni inositol monophosphatase 0.0037 0.0529 0.0513
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0222 0.0246
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.0222 0.0206
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0037 0.0529 0.0769
Schistosoma mansoni skd/vacuolar sorting 0.0027 0.0356 0.034
Brugia malayi Phosphatidylcholine:ceramide cholinephosphotransferase 2 0.0024 0.0283 0.0318
Entamoeba histolytica hypothetical protein 0.0071 0.1184 0.1074
Echinococcus multilocularis thioredoxin glutathione reductase 0.0038 0.0555 0.0555
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.0222 0.0206
Schistosoma mansoni thyroid hormone receptor 0.002 0.0222 0.0206
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0504 0.0596
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.014 0.2505 0.2493
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.0222 0.0246
Trypanosoma cruzi trypanothione reductase, putative 0.0037 0.0546 0.0496
Toxoplasma gondii cell division protein CDC48AP 0.0319 0.5918 0.5885
Plasmodium vivax sphingomyelin synthase 2, putative 0.0024 0.0283 0.0216
Loa Loa (eye worm) nuclear receptor NHR-67 0.001 0.0016 0.0019
Trypanosoma cruzi Valosin-containing protein, putative 0.0506 0.9477 1
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0189 0.0111
Echinococcus granulosus Nuclear hormone receptor HR96 0.001 0.0016 0.0016
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0013 0.008 0.0063
Toxoplasma gondii aldehyde dehydrogenase 0.006 0.0977 0.0904
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0504 0.0727
Leishmania major hypothetical protein, conserved 0.0035 0.0504 0.0452
Loa Loa (eye worm) hypothetical protein 0.0011 0.0038 0.0045
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0016 0.0016
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.002 0.0222 0.0222
Trichomonas vaginalis AAA ATPase, putative 0.0027 0.0356 0.0279
Schistosoma mansoni cpg binding protein 0.0028 0.0373 0.0358
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0189 0.0117
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0504 0.0452
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0189 0.0118
Onchocerca volvulus Protein ultraspiracle homolog 0.002 0.0222 0.0206
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0373 0.0441
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.0222 0.0246
Brugia malayi valosin containing protein 0.0313 0.5795 0.6844
Plasmodium falciparum cell division cycle protein 48 homologue, putative 0.0506 0.9477 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0222 0.0246
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.006 0.0977 0.0977
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0189 0.0188
Onchocerca volvulus 0.0035 0.0504 0.0489
Loa Loa (eye worm) DR-78 0.001 0.0016 0.0019
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.014 0.2505 0.2505
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0013 0.008 0.0001
Brugia malayi Inositol-1 0.0037 0.0529 0.0609
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0504 0.0727
Loa Loa (eye worm) steroid hormone receptor 0.002 0.0222 0.0263
Mycobacterium tuberculosis Conserved protein 0.0035 0.0504 0.0727
Echinococcus granulosus vacuolar protein sorting associated protein 4A 0.0027 0.0356 0.0356
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0189 0.0189
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0504 0.0504
Loa Loa (eye worm) hypothetical protein 0.0024 0.0283 0.0335
Trichomonas vaginalis sphingomyelin synthetase, putative 0.0024 0.0283 0.0205
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0187 0.0114
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0187 0.0108
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0222 0.0246
Mycobacterium ulcerans beta-lactamase 0.0035 0.0504 0.0727
Loa Loa (eye worm) hypothetical protein 0.001 0.0016 0.0019
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0187 0.0183
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0013 0.008 0.0001
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0189 0.0117
Giardia lamblia AAA family ATPase 0.0319 0.5918 1
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0486 0.0559
Echinococcus granulosus dnaJ subfamily B 0.0404 0.7533 0.7533
Giardia lamblia SKD1 protein 0.0027 0.0356 0.0474
Loa Loa (eye worm) hypothetical protein 0.0035 0.0504 0.0596
Echinococcus multilocularis fidgetin protein 1 0.0027 0.0356 0.0356
Loa Loa (eye worm) hypothetical protein 0.0121 0.2141 0.2531
Echinococcus multilocularis FTZ F1 alpha 0.002 0.0222 0.0222
Schistosoma mansoni cpg binding protein 0.003 0.0404 0.0388
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0977 0.1537
Onchocerca volvulus Transitional endoplasmic reticulum ATPase homolog 0.0534 1 1
Plasmodium falciparum sphingomyelin synthase 1, putative 0.0024 0.0283 0.0216
Echinococcus granulosus katanin p60 ATPase containing subunit A1 0.0027 0.0356 0.0356
Entamoeba histolytica ATPase, Vps4 oligomerisation domain containing protein 0.0027 0.0356 0.0182
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0189 0.0118
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0504 0.0452
Entamoeba histolytica cdc48-like protein, putative 0.0506 0.9477 1
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.002 0.0222 0.0206
Echinococcus granulosus thioredoxin glutathione reductase 0.0038 0.0555 0.0555
Plasmodium falciparum thioredoxin reductase 0.0037 0.0546 0.0496
Loa Loa (eye worm) hypothetical protein 0.0035 0.0504 0.0596
Loa Loa (eye worm) hypothetical protein 0.0237 0.4342 0.5132
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0222 0.0222
Brugia malayi orphan nuclear receptor NR2E1 0.001 0.0016 0.0003
Trypanosoma brucei katanin, putative 0.0027 0.0356 0.0295
Brugia malayi nuclear hormone receptor 0.002 0.0222 0.0246
Schistosoma mansoni cell division control protein 48 aaa family protein 0.0221 0.4037 0.4027
Trypanosoma brucei katanin, putative 0.0027 0.0356 0.0295
Plasmodium vivax glutathione reductase, putative 0.0037 0.0546 0.0496
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0529 0.0453
Onchocerca volvulus 0.0028 0.0373 0.0358
Giardia lamblia DINP protein human, muc B family 0.0019 0.0189 0.0188
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0189 0.0189
Trichomonas vaginalis sphingomyelin synthetase, putative 0.0024 0.0283 0.0205
Trypanosoma cruzi katanin, putative 0.0027 0.0356 0.0294
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.001 0.0016 0.0016
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.014 0.2505 0.2949
Echinococcus multilocularis vacuolar protein sorting associated protein 4A 0.0027 0.0356 0.0356
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0135 0.016
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0222 0.0246
Loa Loa (eye worm) hypothetical protein 0.002 0.0222 0.0263
Trypanosoma brucei unspecified product 0.0019 0.0189 0.0118
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0135 0.0135
Loa Loa (eye worm) hypothetical protein 0.001 0.0016 0.0019
Mycobacterium leprae conserved hypothetical protein 0.0035 0.0504 0.0411
Echinococcus multilocularis cpg binding protein 0.003 0.0404 0.0404
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0189 0.0118
Brugia malayi Nuclear hormone receptor E75 0.001 0.0016 0.0003
Leishmania major katanin, putative,serine peptidase, Clan SJ, family S16, putative 0.0027 0.0356 0.0294
Trichomonas vaginalis hypothetical protein 0.0024 0.0283 0.0205
Plasmodium vivax thioredoxin reductase, putative 0.0037 0.0546 0.0496
Schistosoma mansoni hypothetical protein 0.0016 0.0135 0.0119
Mycobacterium tuberculosis Probable dehydrogenase 0.0085 0.1459 0.2362
Onchocerca volvulus 0.0048 0.0753 0.0737
Echinococcus multilocularis geminin 0.0171 0.3082 0.3082
Echinococcus granulosus dna polymerase eta 0.0019 0.0189 0.0189
Schistosoma mansoni hypothetical protein 0.0048 0.0753 0.0737
Entamoeba histolytica hypothetical protein 0.0024 0.0283 0.0104
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0189 0.0117
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0504 0.0727
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0504 0.0727
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0189 0.0118
Entamoeba histolytica hypothetical protein 0.0024 0.0283 0.0104
Loa Loa (eye worm) hypothetical protein 0.0453 0.8461 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.0504 0.0596
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0189 0.0118
Schistosoma mansoni hypothetical protein 0.0171 0.3082 0.3071
Schistosoma mansoni coup transcription factor 0.002 0.0222 0.0206
Brugia malayi hypothetical protein 0.0121 0.2141 0.2518
Loa Loa (eye worm) beta-lactamase 0.0035 0.0504 0.0596
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0011 0.0038 0.0022
Brugia malayi beta-lactamase 0.0035 0.0504 0.058
Brugia malayi beta-lactamase family protein 0.0035 0.0504 0.058
Trypanosoma cruzi katanin, putative 0.0027 0.0356 0.0294
Plasmodium falciparum sphingomyelin synthase 1, putative 0.0024 0.0283 0.0216
Echinococcus granulosus Nuclear hormone receptor HR96 0.001 0.0016 0.0016
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0095 0.164 0.2673
Trichomonas vaginalis skd/vacuolar sorting, putative 0.0027 0.0356 0.0279
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0189 0.0118
Loa Loa (eye worm) hypothetical protein 0.002 0.0222 0.0263
Loa Loa (eye worm) hypothetical protein 0.0121 0.2141 0.2531
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0085 0.1459 0.2362
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.014 0.2505 0.2505
Loa Loa (eye worm) nuclear receptor nhr-7B 0.001 0.0016 0.0019
Loa Loa (eye worm) fidgetin protein 0.0027 0.0356 0.0421
Trichomonas vaginalis spermatogenesis associated factor, putative 0.0534 1 1
Echinococcus multilocularis dnaJ subfamily B 0.0404 0.7533 0.7533
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0189 0.0118
Trypanosoma brucei katanin, putative 0.0027 0.0356 0.0295
Brugia malayi hypothetical protein 0.001 0.0016 0.0003
Giardia lamblia Katanin 0.0027 0.0356 0.0474
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0085 0.1459 0.2362
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0189 0.0189
Loa Loa (eye worm) thioredoxin reductase 0.0037 0.0546 0.0645
Echinococcus multilocularis survival motor neuron protein 1 0.0237 0.4342 0.4342
Loa Loa (eye worm) hypothetical protein 0.0024 0.0283 0.0335
Entamoeba histolytica hypothetical membrane-spanning protein 0.0024 0.0283 0.0104
Brugia malayi hypothetical protein 0.0011 0.0038 0.0029
Loa Loa (eye worm) hypothetical protein 0.002 0.0222 0.0263
Loa Loa (eye worm) hypothetical protein 0.002 0.0222 0.0263
Schistosoma mansoni hypothetical protein 0.0016 0.0135 0.0119
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0529 0.0478
Schistosoma mansoni spingomyelin synthetase-related 0.0024 0.0283 0.0267
Schistosoma mansoni hypothetical protein 0.0404 0.7533 0.7529
Leishmania major Transitional endoplasmic reticulum ATPase, putative,valosin-containing protein homolog 0.0506 0.9477 1
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0135 0.0135
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0189 0.0173
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0189 0.0118
Brugia malayi nuclear receptor RXR 0.0011 0.0038 0.0029
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0187 0.0108
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0013 0.008 0.0001
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0189 0.0207
Trypanosoma brucei inositol phosphorylceramide synthase 0.0024 0.0283 0.0217
Echinococcus multilocularis ecdysone induced protein 78C 0.002 0.0222 0.0222
Brugia malayi SAP1 protein 0.0027 0.0356 0.0405
Brugia malayi Nuclear hormone receptor E75 0.001 0.0016 0.0003
Echinococcus granulosus ecdysone induced protein 78C 0.002 0.0222 0.0222
Loa Loa (eye worm) vps4b-prov protein 0.0027 0.0356 0.0421
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0095 0.164 0.2673
Brugia malayi conserved hypotetical protein 0.001 0.0016 0.0003
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0189 0.0118
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0189 0.0117
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.014 0.2505 0.2505
Echinococcus multilocularis Nuclear hormone receptor HR96 0.001 0.0016 0.0016
Echinococcus multilocularis dna polymerase eta 0.0019 0.0189 0.0189
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.002 0.0222 0.0222
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0189 0.0111
Loa Loa (eye worm) hypothetical protein 0.0024 0.0283 0.0335
Brugia malayi nuclear hormone receptor family member nhr-6 0.001 0.0016 0.0003
Trypanosoma brucei vacuolar protein sorting-associated protein 4, putative 0.0027 0.0356 0.0295
Loa Loa (eye worm) hypothetical protein 0.0313 0.5795 0.685
Brugia malayi beta-lactamase family protein 0.0035 0.0504 0.058
Brugia malayi Calcitonin receptor-like protein seb-1 0.005 0.0789 0.0917
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0095 0.164 1
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0222 0.0206
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.0222 0.0246
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0189 0.0173
Brugia malayi nuclear hormone receptor family member odr-7 0.001 0.0016 0.0003
Loa Loa (eye worm) VCP protein 0.0221 0.4037 0.4772
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0187 0.0187
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0038 0.0029
Echinococcus multilocularis nuclear receptor nhr 48 0.001 0.0016 0.0016
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0189 0.0118
Loa Loa (eye worm) ATPase 0.0027 0.0356 0.0421
Schistosoma mansoni survival motor neuron protein 0.0048 0.0753 0.0737
Echinococcus granulosus survival motor neuron protein 1 0.0237 0.4342 0.4342
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.0753 0.0874
Trypanosoma cruzi katanin-like protein, putative 0.0027 0.0356 0.0294
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0504 0.0727
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0504 0.0727
Mycobacterium ulcerans lipase LipD 0.0035 0.0504 0.0727
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0504 0.0428
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0011 0.0038 0.0038
Leishmania major katanin-like protein,serine peptidase, Clan SJ, family S16, putative 0.0027 0.0356 0.0294
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0011 0.0038 0.0045
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0977 0.1537
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0085 0.1459 0.2362
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0189 0.0118
Trypanosoma cruzi katanin, putative 0.0027 0.0356 0.0294
Loa Loa (eye worm) hypothetical protein 0.001 0.0016 0.0019
Echinococcus granulosus cpg binding protein 0.003 0.0404 0.0404
Echinococcus multilocularis GPCR, family 2 0.0016 0.0135 0.0135
Trichomonas vaginalis sphingomyelin synthetase, putative 0.0024 0.0283 0.0205
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0187 0.0114
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0504 0.0428
Toxoplasma gondii transitional endoplasmic reticulum ATPase, putative 0.0319 0.5917 0.5885
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0504 0.0727
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.0222 0.0263
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0977 0.0962
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0977 0.0962
Trypanosoma brucei ceramide phosphorylethanolamine synthase 0.0024 0.0283 0.0217
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.0222 0.0246
Leishmania major katanin-like protein,serine peptidase, Clan SJ, family S16, putative 0.0027 0.0356 0.0294
Brugia malayi Sphingomyelin synthase-related 1 0.0024 0.0283 0.0318
Loa Loa (eye worm) inositol-1 0.0037 0.0529 0.0625
Echinococcus multilocularis transitional endoplasmic reticulum atpase 0.0221 0.4037 0.4037
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0504 0.0727
Brugia malayi CXXC zinc finger family protein 0.0028 0.0373 0.0425
Giardia lamblia SKD1 protein 0.0027 0.0356 0.0474
Brugia malayi ecdysteroid receptor 0.002 0.0222 0.0246
Plasmodium vivax sphingomyelin synthase 1, putative 0.0024 0.0283 0.0216
Plasmodium falciparum sphingomyelin synthase 2, putative 0.0024 0.0283 0.0216
Schistosoma mansoni hypothetical protein 0.0016 0.0135 0.0119
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.0222 0.0206
Loa Loa (eye worm) hypothetical protein 0.001 0.0016 0.0019
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0189 0.0118
Trypanosoma cruzi metalloprotease, putative 0.0027 0.0356 0.0294
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.0222 0.0263
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0016 0.0016
Schistosoma mansoni cell division control protein 48 aaa family protein 0.0534 1 1
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0187 0.2384
Entamoeba histolytica hypothetical protein 0.0024 0.0283 0.0104
Echinococcus granulosus fidgetin protein 1 0.0027 0.0356 0.0356
Brugia malayi Thioredoxin reductase 0.0037 0.0546 0.0629
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.001 0.0016 0.0016
Schistosoma mansoni hypothetical protein 0.0034 0.0486 0.047
Trypanosoma cruzi vacuolar protein sorting-associated protein 4, putative 0.0027 0.0356 0.0294
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.006 0.0977 0.0955
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0038 0.0029
Loa Loa (eye worm) hypothetical protein 0.002 0.0222 0.0263
Loa Loa (eye worm) hypothetical protein 0.002 0.0222 0.0263
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.002 0.0222 0.0222
Loa Loa (eye worm) hypothetical protein 0.001 0.0016 0.0019
Trypanosoma cruzi katanin-like protein, putative 0.0027 0.0356 0.0294
Onchocerca volvulus 0.0035 0.0504 0.0489
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0504 0.0489
Brugia malayi ATPase, AAA family protein 0.0027 0.0356 0.0405
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0189 0.0188
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0222 0.0246
Echinococcus multilocularis sphingomyelin synthase protein 1 0.0024 0.0283 0.0283
Loa Loa (eye worm) hypothetical protein 0.001 0.0016 0.0019
Echinococcus granulosus thyroid hormone receptor alpha 0.001 0.0016 0.0016
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0187 0.0114
Loa Loa (eye worm) hypothetical protein 0.002 0.0222 0.0263
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.0222 0.0263
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0222 0.0246
Mycobacterium tuberculosis Conserved protein 0.0035 0.0504 0.0727
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0011 0.0038 0.0022
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.001 0.0016 0.0016
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0187 0.0221
Echinococcus granulosus sphingomyelin synthase protein 1 0.0024 0.0283 0.0283
Entamoeba histolytica hypothetical protein 0.0024 0.0283 0.0104
Schistosoma mansoni ap endonuclease 0.0019 0.0187 0.0171
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0071 0.1184 0.1184
Brugia malayi fidgetin protein 0.0027 0.0356 0.0405
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0187 0.0204
Entamoeba histolytica transitional endoplasmic reticulum ATPase, putative 0.0506 0.9477 1
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0504 0.0428
Onchocerca volvulus Huntingtin homolog 0.0121 0.2141 0.2128
Entamoeba histolytica hypothetical protein 0.0071 0.1184 0.1074
Trypanosoma cruzi sphingomyelin/ceramide phosphorylethanolamine synthase, bifunctional 0.0024 0.0283 0.0216
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0189 0.0118
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0504 0.058
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0504 0.0428
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.002 0.0222 0.0222
Trypanosoma brucei Valosin-containing protein 0.0506 0.9477 1
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.002 0.0222 0.0206
Loa Loa (eye worm) hypothetical protein 0.001 0.0016 0.0019
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0189 0.0188
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0037 0.0529 0.0453
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0013 0.008 0.5
Trypanosoma brucei sphingomyelin/ceramide phosphorylethanolamine synthase, bifunctional 0.0024 0.0283 0.0217
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0189 0.0003
Loa Loa (eye worm) hypothetical protein 0.005 0.0789 0.0932
Leishmania major DNA polymerase kappa, putative 0.0019 0.0189 0.0117
Toxoplasma gondii hypothetical protein 0.0024 0.0283 0.0205
Toxoplasma gondii histone lysine methyltransferase SET1 0.0054 0.0857 0.0784
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0189 0.0224
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.014 0.2505 0.2961
Trypanosoma brucei metalloprotease, putative 0.0027 0.0356 0.0295
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0529 0.0453
Trypanosoma cruzi vacuolar transport protein 4A, putative 0.0027 0.0356 0.0294
Schistosoma mansoni transcription factor LCR-F1 0.0071 0.1184 0.117
Loa Loa (eye worm) hypothetical protein 0.001 0.0016 0.0019
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0222 0.0222
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0977 0.1537
Leishmania major trypanothione reductase 0.0037 0.0546 0.0496
Trypanosoma brucei trypanothione reductase 0.0037 0.0546 0.0497
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0085 0.1459 0.8468
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.0456 0.0644
Leishmania major phosphatidylcholine:ceramide cholinephosphotransferase 2 0.0024 0.0283 0.0216
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0504 0.0504
Entamoeba histolytica vacuolar sorting protein-associating protein 4A (VPS4), putative 0.0027 0.0356 0.0182
Schistosoma mansoni nuclear hormone receptor 0.002 0.0222 0.0206
Brugia malayi hypothetical protein 0.0237 0.4342 0.5124
Schistosoma mansoni inositol monophosphatase 0.0037 0.0529 0.0513
Schistosoma mansoni hypothetical protein 0.0071 0.1184 0.117
Brugia malayi nuclear hormone receptor 0.001 0.0016 0.0003
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.006 0.0977 0.0977
Onchocerca volvulus Huntingtin homolog 0.0121 0.2141 0.2128
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.0222 0.0263
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0013 0.008 0.0078
Brugia malayi Phosphatidylcholine:ceramide cholinephosphotransferase 1 0.0024 0.0283 0.0318
Echinococcus granulosus FTZ F1 alpha 0.002 0.0222 0.0222
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0011 0.0038 0.0038
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0187 0.0114
Loa Loa (eye worm) hypothetical protein 0.001 0.0016 0.0019
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.0222 0.0206
Giardia lamblia Topoisomerase II 0.0027 0.0356 0.0474
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0222 0.0222
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.006 0.0977 0.1537
Trichomonas vaginalis spastin, putative 0.0027 0.0356 0.0279
Toxoplasma gondii thioredoxin reductase 0.0037 0.0546 0.047
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0189 0.0207
Schistosoma mansoni thyroid hormone receptor 0.002 0.0222 0.0206
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0504 0.0428
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0085 0.1459 0.2362
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0135 0.0135
Brugia malayi tailless protein 0.001 0.0016 0.0003
Trypanosoma cruzi sphingomyelin/ceramide phosphorylethanolamine synthase, bifunctional 0.0024 0.0283 0.0216
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.0222 0.0246
Brugia malayi nuclear receptor RXR 0.001 0.0016 0.0003
Trichomonas vaginalis 26S protease regulatory subunit S10b, putative 0.0126 0.2236 0.2174
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.098 0.0965
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0037 0.0546 0.0798
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.014 0.2505 0.2493
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.002 0.0222 0.0222
Brugia malayi nuclear receptor NHR-88 0.002 0.0222 0.0246
Echinococcus granulosus nuclear receptor nhr 48 0.001 0.0016 0.0016
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0529 0.0479
Trypanosoma brucei katanin, putative 0.0027 0.0356 0.0295
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0225 0.4124 0.6928
Onchocerca volvulus 0.0035 0.0504 0.0489
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.0222 0.0246
Toxoplasma gondii exonuclease III APE 0.0019 0.0187 0.0108
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.0222 0.0246
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0504 0.0727
Brugia malayi Steroid receptor seven-up type 2 0.002 0.0222 0.0246
Onchocerca volvulus Bile acid receptor homolog 0.002 0.0222 0.0206
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0529 0.0478
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0283 0.0205
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0187 1
Brugia malayi vps4b-prov protein 0.0027 0.0356 0.0405
Mycobacterium tuberculosis Putative conserved ATPase 0.0319 0.5918 1
Brugia malayi nuclear receptor NHR-88 0.001 0.0016 0.0003
Brugia malayi vesicle-fusing ATPase 0.0313 0.5795 0.6844
Loa Loa (eye worm) hypothetical protein 0.0019 0.0189 0.0224
Schistosoma mansoni ap endonuclease 0.0019 0.0187 0.0171
Brugia malayi Cytochrome P450 family protein 0.0023 0.0278 0.0313
Entamoeba histolytica hypothetical protein 0.0071 0.1184 0.1074
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.0222 0.0206
Loa Loa (eye worm) hypothetical protein 0.0024 0.0283 0.0335
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0037 0.0529 0.0368
Echinococcus multilocularis Nuclear hormone receptor HR96 0.001 0.0016 0.0016
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.0222 0.0206
Mycobacterium ulcerans ATPase 0.0319 0.5918 1
Echinococcus granulosus inositol monophosphatase 1 0.0037 0.0529 0.0529
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0504 0.0452
Loa Loa (eye worm) hypothetical protein 0.0016 0.0135 0.016
Echinococcus granulosus retinoic acid receptor rxr beta a 0.002 0.0222 0.0222
Echinococcus granulosus dna polymerase kappa 0.0019 0.0189 0.0189
Schistosoma mansoni DNA polymerase eta 0.0019 0.0189 0.0173
Brugia malayi hypothetical protein 0.001 0.0016 0.0003

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) > 100 uM Cytotoxicity against human U251 cells assessed as cell viability after 24 hrs by MTT assay ChEMBL. 23167526

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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