Detailed information for compound 1766023

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 343.285 | Formula: C16H16N4Se
  • H donors: 0 H acceptors: 3 LogP: 2.32 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1ccc(cc1)c1cc2c([se]1)c(nnn2)N1CCCC1
  • InChi: 1S/C16H16N4Se/c1-11-4-6-12(7-5-11)14-10-13-15(21-14)16(18-19-17-13)20-8-2-3-9-20/h4-7,10H,2-3,8-9H2,1H3
  • InChiKey: DARDDJYBOGFTDH-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0018 0.0000039443 0.0000089478
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0021 0.0013 0.0026
Schistosoma mansoni adenoreceptor 0.0021 0.0013 0.0026
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0114 0.0233
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0013 0.0026
Mycobacterium tuberculosis Probable oxidoreductase 0.0119 0.0419 0.0482
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0205 0.0775 0.1573
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0021 0.0013 0.0026
Leishmania major DNA polymerase eta, putative 0.0019 0.0005 0.0011
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0018 0.0000039443 0.0000089478
Schistosoma mansoni hypothetical protein 0.0021 0.0013 0.0026
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0000039443 0.0000080118
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0107 0.037 0.0425
Schistosoma mansoni opsin-like receptor 0.0021 0.0013 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.0063 0.0187 1
Echinococcus granulosus tm gpcr rhodopsin 0.0021 0.0013 0.0026
Echinococcus multilocularis serotonin receptor 0.0258 0.0998 0.2027
Echinococcus granulosus 7tm_1 domain containing protein 0.0021 0.0013 0.0026
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0205 0.0775 0.1573
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0013 0.0026
Schistosoma mansoni hypothetical protein 0.0166 0.0616 0.1252
Onchocerca volvulus Vesicular acetylcholine transporter homolog 0.0216 0.0822 0.1647
Toxoplasma gondii hypothetical protein 0.0205 0.0775 0.6357
Brugia malayi Cytochrome P450 family protein 0.0056 0.0158 0.032
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0005 0.001
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0026
Schistosoma mansoni biogenic amine (5HT) receptor 0.0258 0.0998 0.2027
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0021 0.0013 0.0026
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0026
Echinococcus multilocularis G protein coupled receptor 139 0.0021 0.0013 0.0026
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0205 0.0775 0.6357
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0047 0.0121 0.0139
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0021 0.0013 0.0026
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0026
Echinococcus granulosus alpha 1A adrenergic receptor 0.0021 0.0013 0.0026
Echinococcus granulosus neuropeptide receptor 0.0021 0.0013 0.0026
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0205 0.0775 0.1573
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0021 0.0013 0.0026
Brugia malayi Serotonin receptor 0.0021 0.0013 0.0026
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0021 0.0013 0.0026
Plasmodium vivax hypothetical protein, conserved 0.0312 0.1218 1
Loa Loa (eye worm) hypothetical protein 0.0205 0.0775 0.1573
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0114 0.0233
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0018 0.0000039443 0.0000080118
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0005 0.0264
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0021 0.0013 0.0026
Loa Loa (eye worm) hypothetical protein 0.0205 0.0775 0.1573
Brugia malayi Sodium:neurotransmitter symporter family protein 0.1205 0.4923 1
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0205 0.0775 0.1573
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0205 0.0775 0.1573
Brugia malayi G-protein coupled receptor 0.0021 0.0013 0.0026
Schistosoma mansoni vesicular acetylcholine transporter 0.0216 0.0822 0.167
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0018 0.0000039443 0.0000089478
Brugia malayi hypothetical protein 0.0021 0.0013 0.0026
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0114 0.0233
Schistosoma mansoni SWI/SNF complex-related 0.0063 0.0187 0.0381
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0028 0.1469
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0026
Loa Loa (eye worm) G-protein coupled receptor 0.0021 0.0013 0.0026
Brugia malayi Serotonin receptor 0.0021 0.0013 0.0026
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0021 0.0013 0.0026
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0024 0.0028 0.0063
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0114 0.0233
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0905 0.3676 0.7467
Schistosoma mansoni opsin-like receptor 0.0021 0.0013 0.0026
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0005 0.0264
Schistosoma mansoni vesicular amine transporter 0.037 0.146 0.2965
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0021 0.0013 0.0026
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0005 0.0011
Mycobacterium tuberculosis Probable reductase 0.0107 0.037 0.0425
Echinococcus granulosus biogenic amine 5HT receptor 0.0258 0.0998 0.2027
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0021 0.0013 0.0026
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0013 0.0026
Loa Loa (eye worm) hypothetical protein 0.0205 0.0775 0.1573
Trypanosoma brucei trypanothione reductase 0.0047 0.0121 0.0274
Echinococcus granulosus rhodopsin orphan GPCR 0.0021 0.0013 0.0026
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0026
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0024 0.0028 0.0056
Brugia malayi Cytochrome P450 family protein 0.0026 0.0036 0.0073
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0021 0.0013 0.0026
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0021 0.0013 0.0026
Trypanosoma brucei C-8 sterol isomerase, putative 0.1081 0.4408 1
Leishmania major phosphatidylinositol 3-kinase, putative 0.0018 0.0000039443 0.0000089478
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0021 0.0013 0.0026
Leishmania major UDP-galactopyranose mutase 0.0312 0.1218 0.2764
Trypanosoma brucei cytochrome P450, putative 0.0026 0.0036 0.0082
Entamoeba histolytica hypothetical protein 0.0036 0.0074 0.3967
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0026
Echinococcus multilocularis somatostatin receptor 0.0021 0.0013 0.0026
Schistosoma mansoni myosin xvIII 0.0021 0.0013 0.0026
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0005 0.0011
Echinococcus multilocularis neuropeptide receptor 0.0021 0.0013 0.0026
Entamoeba histolytica hypothetical protein 0.0024 0.0028 0.1469
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0005 0.0011
Schistosoma mansoni histamine h1 receptor 0.0021 0.0013 0.0026
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0018 0.0000039443 0.0000080118
Mycobacterium ulcerans oxidoreductase 0.0312 0.1218 0.1218
Brugia malayi G protein-coupled receptor F59B2.13 0.0021 0.0013 0.0026
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0205 0.0775 0.1573
Brugia malayi AKH receptor 0.0021 0.0013 0.0026
Echinococcus multilocularis sex peptide receptor 0.0021 0.0013 0.0026
Schistosoma mansoni sodium/chloride dependent transporter 0.0205 0.0775 0.1573
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0312 0.1218 1
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0021 0.0013 0.0026
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0205 0.0775 0.1573
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0026
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0021 0.0013 0.0026
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0005 0.0006
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0021 0.0013 0.0026
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0205 0.0775 0.1573
Trypanosoma cruzi cytochrome P450, putative 0.0026 0.0036 0.0082
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0107 0.037 0.0425
Brugia malayi Myb-like DNA-binding domain containing protein 0.0196 0.074 0.1504
Leishmania major trypanothione reductase 0.0047 0.0121 0.0274
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0026
Schistosoma mansoni amine oxidase 0.0312 0.1218 0.2475
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0018 0.0000039443 0.0000089478
Loa Loa (eye worm) melatonin receptor type 1A 0.0021 0.0013 0.0026
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0018 0.0000039443 0.0000089478
Toxoplasma gondii histone lysine-specific demethylase 0.0312 0.1218 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0026
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0312 0.1218 1
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0021 0.0013 0.0026
Brugia malayi Dopamine receptor 0.0021 0.0013 0.0026
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0026
Schistosoma mansoni hypothetical protein 0.0036 0.0074 0.0151
Echinococcus multilocularis g-protein coupled receptor 0.0021 0.0013 0.0026
Echinococcus granulosus serotonin receptor 0.0021 0.0013 0.0026
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0005 0.0006
Echinococcus granulosus hypothetical protein 0.0021 0.0013 0.0026
Echinococcus multilocularis serotonin transporter 0.1205 0.4923 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0021 0.0013 0.0026
Echinococcus multilocularis vesicular acetylcholine transporter 0.0216 0.0822 0.167
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0205 0.0775 0.1573
Echinococcus granulosus g-protein coupled receptor 0.0021 0.0013 0.0026
Schistosoma mansoni neuropeptide receptor 0.0021 0.0013 0.0026
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0026 0.0036 0.0036
Schistosoma mansoni sodium/chloride dependent transporter 0.1205 0.4923 1
Schistosoma mansoni neuropeptide f receptor 76f 0.0021 0.0013 0.0026
Schistosoma mansoni amine GPCR 0.0021 0.0013 0.0026
Loa Loa (eye worm) hypothetical protein 0.0063 0.0187 0.0381
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0005 0.001
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0205 0.0775 0.1573
Onchocerca volvulus 0.0205 0.0775 0.1551
Brugia malayi neuropeptide F receptor 0.0021 0.0013 0.0026
Loa Loa (eye worm) hypothetical protein 0.0553 0.2217 0.4503
Loa Loa (eye worm) abnormal catecholamine distribution protein 1 0.037 0.146 0.2965
Brugia malayi SWIRM domain containing protein 0.0063 0.0187 0.0381
Brugia malayi GnHR receptor homolog 0.0021 0.0013 0.0026
Echinococcus granulosus serine protein kinase ATM 0.0024 0.0028 0.0056
Echinococcus granulosus neuropeptide FF receptor 2 0.0021 0.0013 0.0026
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.1205 0.4923 1
Schistosoma mansoni sodium/chloride dependent transporter 0.0205 0.0775 0.1573
Loa Loa (eye worm) serotonin transporter b 0.1205 0.4923 1
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0005 0.0005
Loa Loa (eye worm) cytochrome P450 family protein 0.0056 0.0158 0.032
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0021 0.0013 0.0026
Echinococcus granulosus somatostatin receptor 0.0021 0.0013 0.0026
Echinococcus multilocularis neuropeptide s receptor 0.0021 0.0013 0.0026
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0205 0.0775 0.1573
Echinococcus granulosus biogenic amine 5HT receptor 0.0021 0.0013 0.0026
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0312 0.1218 1
Plasmodium vivax hypothetical protein, conserved 0.0205 0.0775 0.5956
Mycobacterium tuberculosis Probable dehydrogenase 0.0107 0.037 0.0425
Brugia malayi G-protein coupled receptor 0.0021 0.0013 0.0026
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.243 1 1
Trypanosoma cruzi trypanothione reductase, putative 0.0047 0.0121 0.0274
Schistosoma mansoni opsin-like receptor 0.0021 0.0013 0.0026
Loa Loa (eye worm) hypothetical protein 0.0258 0.0998 0.2027
Echinococcus granulosus rhodopsin orphan GPCR 0.0021 0.0013 0.0026
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0114 0.0233
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0005 0.001
Echinococcus granulosus neuropeptides capa receptor 0.0021 0.0013 0.0026
Treponema pallidum sodium- and chloride- dependent transporter 0.1205 0.4923 1
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0021 0.0013 0.0026
Echinococcus granulosus lysine specific histone demethylase 1A 0.0312 0.1218 0.2475
Echinococcus granulosus neuropeptide receptor A26 0.0021 0.0013 0.0026
Echinococcus multilocularis g protein coupled receptor 0.0021 0.0013 0.0026
Echinococcus granulosus rhodopsin orphan GPCR 0.0021 0.0013 0.0026
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0114 0.0233
Leishmania major DNA polymerase kappa, putative 0.0019 0.0005 0.0011
Echinococcus granulosus 7TM GPCR rhodopsin 0.0021 0.0013 0.0026
Schistosoma mansoni growth hormone secretagogue receptor 0.0021 0.0013 0.0026
Brugia malayi putative neuropeptide receptor 0.0021 0.0013 0.0026
Brugia malayi hypothetical protein 0.0021 0.0013 0.0026
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0021 0.0013 0.0026
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0018 0.0000039443 0.0000080118
Echinococcus multilocularis neuropeptide Y receptor 0.0021 0.0013 0.0026
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.0000039443 0.0000089478
Echinococcus granulosus rhodopsin orphan GPCR 0.0021 0.0013 0.0026
Brugia malayi amine oxidase, flavin-containing family protein 0.0375 0.1479 0.3005
Echinococcus granulosus neuropeptide Y receptor 0.0021 0.0013 0.0026
Schistosoma mansoni amine GPCR 0.0021 0.0013 0.0026
Brugia malayi RE15519p 0.0021 0.0013 0.0026
Loa Loa (eye worm) hypothetical protein 0.1205 0.4923 1
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0018 0.0000039443 0.0000089478
Echinococcus multilocularis synaptic vesicular amine transporter 0.037 0.146 0.2965
Schistosoma mansoni hypothetical protein 0.0021 0.0013 0.0026
Echinococcus granulosus sodium and chloride dependent glycine 0.0205 0.0775 0.1573
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0021 0.0013 0.0026
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0018 0.0000039443 0.0000080118
Toxoplasma gondii FATC domain-containing protein 0.0024 0.0028 0.0226
Loa Loa (eye worm) hypothetical protein 0.0205 0.0775 0.1573
Echinococcus multilocularis g protein coupled receptor 0.0021 0.0013 0.0026
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0021 0.0013 0.0026
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0205 0.0775 0.1573
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0021 0.0013 0.0026
Loa Loa (eye worm) hypothetical protein 0.1205 0.4923 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0129 0.0263
Plasmodium falciparum amino acid transporter, putative 0.0205 0.0775 0.5956
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0018 0.0000039443 0.0000089478
Loa Loa (eye worm) hypothetical protein 0.1205 0.4923 1
Entamoeba histolytica SWIRM domain protein 0.0063 0.0187 1
Loa Loa (eye worm) hypothetical protein 0.0205 0.0775 0.1573
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.0013 0.0026
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0026
Echinococcus multilocularis sodium and chloride dependent glycine 0.0205 0.0775 0.1573
Echinococcus multilocularis fmrfamide receptor 0.0021 0.0013 0.0026
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0026
Echinococcus granulosus rhodopsin orphan GPCR 0.0021 0.0013 0.0026
Loa Loa (eye worm) hypothetical protein 0.0033 0.0065 0.0132
Loa Loa (eye worm) hypothetical protein 0.0202 0.0764 0.1552
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0021 0.0013 0.0026
Loa Loa (eye worm) hypothetical protein 0.0258 0.0998 0.2027
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0005 0.0011
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0018 0.0000039443 0.0000089478
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0005 0.0011
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0026
Echinococcus multilocularis orexin receptor type 2 0.0021 0.0013 0.0026
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0021 0.0013 0.0026
Loa Loa (eye worm) hypothetical protein 0.0312 0.1218 0.2475
Schistosoma mansoni neuropeptide receptor 0.0021 0.0013 0.0026
Brugia malayi follicle stimulating hormone receptor 0.0021 0.0013 0.0026
Schistosoma mansoni neuropeptide F-like receptor 0.0021 0.0013 0.0026
Schistosoma mansoni neuropeptide F-like receptor 0.0021 0.0013 0.0026
Echinococcus granulosus thioredoxin glutathione reductase 0.0047 0.0121 0.0245
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0005 0.0011
Mycobacterium ulcerans monoamine oxidase 0.0312 0.1218 0.1218
Echinococcus granulosus peptide allatostatin:somatostatin 0.0021 0.0013 0.0026
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.0013 0.0026
Entamoeba histolytica hypothetical protein 0.0036 0.0074 0.3967
Echinococcus granulosus orexin receptor type 2 0.0021 0.0013 0.0026
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0026
Loa Loa (eye worm) hypothetical protein 0.0312 0.1218 0.2475
Schistosoma mansoni neuropeptide receptor 0.0021 0.0013 0.0026
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0021 0.0013 0.0026
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0005 0.0011
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0026
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0024 0.0028 0.0056
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0312 0.1218 0.2475
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0005 0.001
Echinococcus granulosus neuropeptides capa receptor 0.0021 0.0013 0.0026
Brugia malayi ORL1-like opioid receptor 0.0021 0.0013 0.0026
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0205 0.0775 0.6357
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.0013 0.0026
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0026
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0018 0.0000039443 0.0000080118
Echinococcus granulosus fmrfamide receptor 0.0021 0.0013 0.0026
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0026
Echinococcus granulosus dna polymerase kappa 0.0019 0.0005 0.001
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0000039443 0.0000080118
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0000039443 0.0000080118
Echinococcus granulosus tm gpcr rhodopsin 0.0021 0.0013 0.0026
Loa Loa (eye worm) glutathione reductase 0.0047 0.0121 0.0245
Schistosoma mansoni alpha-1 adrenergic receptor 0.0021 0.0013 0.0026
Schistosoma mansoni amine GPCR 0.0021 0.0013 0.0026
Plasmodium vivax amine transporter, putative 0.0205 0.0775 0.5956
Echinococcus multilocularis serotonin receptor 0.0258 0.0998 0.2027
Trichomonas vaginalis conserved hypothetical protein 0.0063 0.0187 1
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0005 0.0011
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.0013 0.0026
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.0013 0.0026
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0905 0.3676 0.7467
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0074 0.0151
Loa Loa (eye worm) hypothetical protein 0.1081 0.4408 0.8954
Chlamydia trachomatis protoporphyrinogen oxidase 0.0312 0.1218 1
Loa Loa (eye worm) neuropeptide F receptor 0.0021 0.0013 0.0026
Brugia malayi Dopamine receptor protein 1 0.0021 0.0013 0.0026
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.0013 0.0026
Plasmodium falciparum transporter, putative 0.0205 0.0775 0.5956
Echinococcus multilocularis neuropeptide Y receptor 0.0021 0.0013 0.0026
Loa Loa (eye worm) G-protein coupled receptor 0.0021 0.0013 0.0026
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0005 0.0011
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0205 0.0775 0.1573
Brugia malayi hypothetical protein 0.0312 0.1218 0.2475
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0026
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0119 0.0419 0.0482
Onchocerca volvulus 0.0968 0.3937 0.7992
Loa Loa (eye worm) thioredoxin reductase 0.0047 0.0121 0.0245
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0005 0.0264
Echinococcus granulosus dna polymerase eta 0.0019 0.0005 0.001
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0021 0.0013 0.0026
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0026
Brugia malayi Tachykinin-like peptides receptor 99D 0.0021 0.0013 0.0026
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0018 0.0000039443 0.0000089478
Brugia malayi neuropeptide F receptor 0.0021 0.0013 0.0026
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0026
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0026
Schistosoma mansoni hypothetical protein 0.0166 0.0616 0.1252
Trypanosoma cruzi target of rapamycin kinase 3 0.0018 0.0000039443 0.0000089478
Echinococcus granulosus allatostatin A receptor 0.0021 0.0013 0.0026
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0797 0.3229 0.6559
Onchocerca volvulus 0.1205 0.4923 1
Echinococcus multilocularis G-protein coupled receptor, putative 0.0021 0.0013 0.0026
Giardia lamblia DINP protein human, muc B family 0.0019 0.0005 0.0264
Trypanosoma brucei unspecified product 0.0019 0.0005 0.0011
Echinococcus multilocularis protoporphyrinogen oxidase 0.0312 0.1218 0.2475
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0119 0.0419 0.3442
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0026
Echinococcus multilocularis SWI:SNF complex subunit SMARCC2 0.0063 0.0187 0.0381
Loa Loa (eye worm) hypothetical protein 0.0905 0.3676 0.7467
Schistosoma mansoni biogenic amine (5HT) receptor 0.0021 0.0013 0.0026
Onchocerca volvulus 0.0205 0.0775 0.1551
Echinococcus granulosus SWI:SNF complex subunit SMARCC2 0.0063 0.0187 0.0381
Echinococcus granulosus sex peptide receptor 0.0021 0.0013 0.0026
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0021 0.0013 0.0026
Schistosoma mansoni amine GPCR 0.0021 0.0013 0.0026
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0129 0.0263
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.001
Schistosoma mansoni biogenic amine receptor 0.0021 0.0013 0.0026
Echinococcus granulosus neuropeptide s receptor 0.0021 0.0013 0.0026
Echinococcus granulosus G protein coupled receptor 139 0.0021 0.0013 0.0026
Loa Loa (eye worm) hypothetical protein 0.0205 0.0775 0.1573
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0205 0.0775 0.1573
Brugia malayi ERG2 and Sigma1 receptor like protein 0.1081 0.4408 0.8954
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0026
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0026
Brugia malayi hypothetical protein 0.0021 0.0013 0.0026
Echinococcus granulosus g protein coupled receptor 0.0021 0.0013 0.0026
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0005 0.0011
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0026
Echinococcus granulosus neuropeptide Y receptor 0.0021 0.0013 0.0026
Toxoplasma gondii hypothetical protein 0.0205 0.0775 0.6357
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0021 0.0013 0.0026
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0026
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0205 0.0775 0.1573
Mycobacterium tuberculosis Conserved hypothetical protein 0.0312 0.1218 0.1399
Loa Loa (eye worm) cytochrome P450 family protein 0.0026 0.0036 0.0073
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.2118 0.8708 1
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0021 0.0013 0.0026
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0119 0.0419 0.0482
Brugia malayi Melatonin receptor type 1A 0.0021 0.0013 0.0026
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0021 0.0013 0.0026
Echinococcus granulosus rhodopsin orphan GPCR 0.0021 0.0013 0.0026
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0114 0.0233
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0026
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0026 0.0033 0.0067
Trypanosoma cruzi C-8 sterol isomerase, putative 0.1081 0.4408 1
Brugia malayi putative neuropeptide receptor NPR1 0.0021 0.0013 0.0026
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0026
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0005 0.0011
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0026
Giardia lamblia hypothetical protein 0.0063 0.0187 1
Schistosoma mansoni amine oxidase 0.0312 0.1218 0.2475
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0312 0.1218 0.1218
Loa Loa (eye worm) hypothetical protein 0.0196 0.074 0.1504
Onchocerca volvulus CoRest homolog 0.0202 0.0764 0.1529
Brugia malayi Dopamine receptor protein 2 0.0021 0.0013 0.0026
Schistosoma mansoni biogenic amine receptor 0.0021 0.0013 0.0026
Echinococcus granulosus g protein coupled receptor 0.0021 0.0013 0.0026
Loa Loa (eye worm) hypothetical protein 0.0205 0.0775 0.1573
Echinococcus granulosus synaptic vesicular amine transporter 0.037 0.146 0.2965
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0021 0.0013 0.0026
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0021 0.0013 0.0026
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0013 0.0026
Echinococcus granulosus lysine specific histone demethylase 1A 0.0905 0.3676 0.7467
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.0013 0.0026
Leishmania major cytochrome p450-like protein 0.0026 0.0036 0.0082
Brugia malayi G protein-coupled receptor 0.0021 0.0013 0.0026
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.0000039443 0.0000089478
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0021 0.0013 0.0026
Echinococcus granulosus vesicular acetylcholine transporter 0.0216 0.0822 0.167
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0107 0.037 0.3036
Schistosoma mansoni hypothetical protein 0.0021 0.0013 0.0026
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0021 0.0013 0.0026
Loa Loa (eye worm) neuropeptide F receptor 0.0021 0.0013 0.0026
Echinococcus granulosus g protein coupled receptor 0.0021 0.0013 0.0026
Plasmodium vivax hypothetical protein, conserved 0.0312 0.1218 1
Plasmodium falciparum protoporphyrinogen oxidase 0.0312 0.1218 1
Brugia malayi hypothetical protein 0.0205 0.0775 0.1573
Echinococcus multilocularis neuropeptides capa receptor 0.0021 0.0013 0.0026
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0013 0.0026
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0005 0.0011
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0205 0.0775 0.6357
Onchocerca volvulus 0.0205 0.0775 0.1551
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0013 0.0026
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0021 0.0013 0.003
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0021 0.0013 0.0026
Loa Loa (eye worm) solute carrier family 6 member 4 0.1205 0.4923 1
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0021 0.0013 0.0026
Brugia malayi hypothetical protein 0.0021 0.0013 0.0026
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0005 0.001
Brugia malayi larval opioid receptor 0.0021 0.0013 0.0026
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0021 0.0013 0.0026
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0026
Echinococcus multilocularis g protein coupled receptor 0.0021 0.0013 0.0026
Loa Loa (eye worm) hypothetical protein 0.0905 0.3676 0.7467
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0026
Echinococcus multilocularis dro:myosuppressin receptor 0.0021 0.0013 0.0026
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0018 0.0000039443 0.0000089478
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0005 0.001
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0026
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0013 0.0026
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0013 0.0026
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0205 0.0775 0.1573
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0024 0.0028 0.0063
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0026
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0205 0.0775 0.1573
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0018 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0968 0.3937 0.7997
Echinococcus multilocularis geminin 0.0166 0.0616 0.1252
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0026
Echinococcus multilocularis thioredoxin glutathione reductase 0.0047 0.0121 0.0245
Brugia malayi hypothetical protein 0.0021 0.0013 0.0026
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.0065 0.0132
Echinococcus multilocularis dna polymerase eta 0.0019 0.0005 0.001
Schistosoma mansoni amine GPCR 0.0021 0.0013 0.0026
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0005 0.0011
Echinococcus granulosus geminin 0.0166 0.0616 0.1252
Echinococcus multilocularis 0.0312 0.1218 0.2475
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0021 0.0013 0.0026
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0074 0.0151
Brugia malayi hypothetical protein 0.0021 0.0013 0.0026
Loa Loa (eye worm) TYRA-2 protein 0.0021 0.0013 0.0026
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.0013 0.0026
Trypanosoma cruzi cytochrome P450, putative 0.0026 0.0036 0.0082
Echinococcus granulosus sodium and chloride dependent glycine 0.0205 0.0775 0.1573
Echinococcus granulosus nmda type glutamate receptor 0.0026 0.0033 0.0067
Entamoeba histolytica hypothetical protein 0.0063 0.0187 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0026
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0005 0.0011
Leishmania major C-8 sterol isomerase-like protein 0.1081 0.4408 1
Entamoeba histolytica SWIRM domain protein 0.0063 0.0187 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0026
Schistosoma mansoni biogenic amine receptor 0.0021 0.0013 0.0026
Echinococcus granulosus tm gpcr rhodopsin 0.0021 0.0013 0.0026
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0018 0.0000039443 0.0000080118
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0026
Echinococcus multilocularis neuropeptides capa receptor 0.0021 0.0013 0.0026
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0114 0.0233
Schistosoma mansoni hypothetical protein 0.0021 0.0013 0.0026
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0107 0.037 0.0425
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0005 0.0011
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0205 0.0775 0.1573
Schistosoma mansoni sodium-dependent amino acid transporter 0.0205 0.0775 0.1573
Echinococcus multilocularis fmrfamide receptor 0.0021 0.0013 0.0026
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0074 0.0151
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0129 0.0263
Brugia malayi Cytochrome P450 family protein 0.0026 0.0036 0.0073
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0312 0.1218 1
Echinococcus multilocularis serine protein kinase ATM 0.0024 0.0028 0.0056
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0205 0.0775 0.1573
Echinococcus granulosus neuropeptide receptor 0.0021 0.0013 0.0026
Schistosoma mansoni neuropeptide receptor 0.0021 0.0013 0.0026
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0026
Brugia malayi SWIRM domain containing protein 0.0968 0.3937 0.7997
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0026
Schistosoma mansoni DNA polymerase eta 0.0019 0.0005 0.001
Echinococcus granulosus rhodopsin orphan GPCR 0.0021 0.0013 0.0026
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0312 0.1218 1
Echinococcus multilocularis sodium and chloride dependent glycine 0.0205 0.0775 0.1573
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0026
Toxoplasma gondii thioredoxin reductase 0.0047 0.0121 0.0992
Brugia malayi hypothetical protein 0.0021 0.0013 0.0026
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0005 0.001
Mycobacterium tuberculosis Possible oxidoreductase 0.0312 0.1218 0.1399
Echinococcus multilocularis neuropeptide FF receptor 2 0.0021 0.0013 0.0026
Echinococcus multilocularis neuropeptide receptor 0.0021 0.0013 0.0026
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0026
Echinococcus multilocularis allatostatin A receptor 0.0021 0.0013 0.0026
Brugia malayi hypothetical protein 0.0021 0.0013 0.0026
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0005 0.0011
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0114 0.0233
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0005 0.0011
Loa Loa (eye worm) hypothetical protein 0.0049 0.0129 0.0263
Brugia malayi hypothetical protein 0.0021 0.0013 0.0026
Brugia malayi hypothetical protein 0.0036 0.0074 0.0151
Loa Loa (eye worm) hypothetical protein 0.0375 0.1479 0.3005
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0205 0.0775 0.1573
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0205 0.0775 0.1573
Loa Loa (eye worm) vesicular acetylcholine transporter unc-17 0.0216 0.0822 0.167
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0026
Echinococcus granulosus dro:myosuppressin receptor 0.0021 0.0013 0.0026
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0005 0.0011
Brugia malayi glutathione reductase 0.0047 0.0121 0.0245
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0027
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0013 0.0026
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0026
Brugia malayi hypothetical protein 0.0021 0.0013 0.0026
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0018 0.0003 0.0003
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0107 0.037 0.0425
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0018 0.0000039443 0.0000089478
Entamoeba histolytica hypothetical protein 0.0036 0.0074 0.3967
Toxoplasma gondii SWIRM domain-containing protein 0.0063 0.0187 0.1537
Echinococcus granulosus serotonin transporter 0.1205 0.4923 1
Echinococcus granulosus tachykinin peptides receptor 99D 0.0021 0.0013 0.0026
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0005 0.001
Brugia malayi sulfakinin receptor protein 0.0021 0.0013 0.0026
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0205 0.0775 0.6348
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0021 0.0013 0.0026
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0021 0.0013 0.0026
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0005 0.0005
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0312 0.1218 1
Trypanosoma cruzi UDP-galactopyranose mutase 0.0312 0.1218 0.2764
Echinococcus multilocularis neuropeptide receptor A26 0.0021 0.0013 0.0026
Entamoeba histolytica hypothetical protein 0.0036 0.0074 0.3967
Brugia malayi Abnormal catecholamine distribution protein 1 0.037 0.146 0.2965
Loa Loa (eye worm) norepinephrine transporter 0.1205 0.4923 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0026 0.0036 0.0073
Brugia malayi Thioredoxin reductase 0.0047 0.0121 0.0245
Brugia malayi vesicular acetylcholine transporter unc-17 0.0216 0.0822 0.167
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0005 0.0011
Loa Loa (eye worm) CYP4Cod1 0.0026 0.0036 0.0073
Trypanosoma cruzi UDP-galactopyranose mutase 0.0312 0.1218 0.2764
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0005 0.0011
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0000039443 0.0000080118
Echinococcus multilocularis nmda type glutamate receptor 0.0026 0.0033 0.0067
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0021 0.0013 0.0026
Schistosoma mansoni hypothetical protein 0.0033 0.0065 0.0132
Mycobacterium ulcerans dehydrogenase 0.0312 0.1218 0.1218

Activities

Activity type Activity value Assay description Source Reference
Inhibition (binding) = 73.5 % Inhibition of human recombinant VEGFR2 at 200 uM ChEMBL. 23583911

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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