TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 562.592 | Formula: C30H32F6N4++
H donors: 2 H acceptors: 0 LogP: 7.94 Rotable bonds: 2
Rule of 5 violations (Lipinski): 2
SMILES: FC(c1ccc2c(c1)c1NCCCCCNc3cc[n+](CCCCC[n+]2cc1)c1ccc(cc31)C(F)(F)F)(F)F
InChi: 1S/C30H30F6N4/c31-29(32,33)21-7-9-27-23(19-21)25-11-17-39(27)15-5-2-6-16-40-18-12-26(38-14-4-1-3-13-37-25)24-20-22(30(34,35)36)8-10-28(24)40/h7-12,17-20H,1-6,13-16H2/p+2/b37-25+,38-26+
InChiKey: ZDYYRJPXPNUUAW-USKKBRKXSA-P

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Trypanosoma brucei	protein kinase, putative	0.0076	0.0044	1
Entamoeba histolytica	protein kinase, putative	0.007	0.0035	0.1619
Trichomonas vaginalis	conserved hypothetical protein	0.0063	0.0026	0.0526
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0208	0.0219	0.4373
Loa Loa (eye worm)	bromodomain containing protein	0.0208	0.0219	0.0219
Trichomonas vaginalis	bromodomain containing protein, putative	0.0063	0.0026	0.0526
Brugia malayi	Bromodomain containing protein	0.0063	0.0026	0.0026
Echinococcus multilocularis	protein kinase C binding protein 1	0.0063	0.0026	0.0026
Brugia malayi	intracellular kinase	0.0076	0.0044	0.0044
Giardia lamblia	Kinase, CMGC GSK	0.0076	0.0044	0.1304
Schistosoma mansoni	bromodomain containing protein	0.0063	0.0026	0.0026
Brugia malayi	polybromodomain protein	0.0063	0.0026	0.0026
Trichomonas vaginalis	lymphoid specific helicase, putative	0.0087	0.0058	0.1156
Loa Loa (eye worm)	hypothetical protein	0.0196	0.0202	0.0202
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0058	0.0058
Schistosoma mansoni	transcription initiation factor tfiid	0.0063	0.0026	0.0026
Trichomonas vaginalis	conserved hypothetical protein	0.0212	0.0224	0.4481
Entamoeba histolytica	PH domain containing protein kinase, putative	0.0056	0.0017	0.0793
Trichomonas vaginalis	conserved hypothetical protein	0.0063	0.0026	0.0526
Giardia lamblia	Kinase, putative	0.0208	0.0219	1
Trypanosoma cruzi	Bromodomain, putative	0.0063	0.0026	0.3417
Trichomonas vaginalis	conserved hypothetical protein	0.0063	0.0026	0.0526
Brugia malayi	bromodomain containing protein	0.0063	0.0026	0.0026
Entamoeba histolytica	bromodomain-containing protein	0.0208	0.0219	1
Echinococcus multilocularis	bromodomain containing protein 7	0.0356	0.0415	0.0415
Brugia malayi	BRM protein	0.0212	0.0224	0.0224
Trypanosoma brucei	rac serine-threonine kinase, putative	0.007	0.0035	0.5261
Loa Loa (eye worm)	STE/STE7/MEK7 protein kinase	0.7578	1	1
Giardia lamblia	Hypothetical protein	0.0063	0.0026	0.0446
Schistosoma mansoni	hypothetical protein	0.0356	0.0415	0.0415
Trichomonas vaginalis	conserved hypothetical protein	0.0063	0.0026	0.0526
Trypanosoma cruzi	hypothetical protein, conserved	0.0063	0.0026	0.3417
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0063	0.0026	0.0526
Entamoeba histolytica	protein kinase domain containing protein	0.0076	0.0044	0.1994
Loa Loa (eye worm)	CMGC/GSK protein kinase	0.0076	0.0044	0.0044
Trichomonas vaginalis	conserved hypothetical protein	0.0063	0.0026	0.0526
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0063	0.0026	0.0526
Plasmodium vivax	hypothetical protein, conserved	0.0063	0.0026	0.0708
Entamoeba histolytica	protein kinase, putative	0.007	0.0035	0.1619
Toxoplasma gondii	bromodomain-containing protein	0.0208	0.0219	1
Trichomonas vaginalis	conserved hypothetical protein	0.0063	0.0026	0.0526
Trypanosoma cruzi	Bromodomain, putative	0.0063	0.0026	0.3417
Echinococcus granulosus	histone acetyltransferase KAT2B	0.032	0.0368	0.0368
Trichomonas vaginalis	conserved hypothetical protein	0.0063	0.0026	0.0526
Trichomonas vaginalis	conserved hypothetical protein	0.0063	0.0026	0.0526
Trichomonas vaginalis	histone acetyltransferase gcn5, putative	0.0208	0.0219	0.4373
Trichomonas vaginalis	AGC family protein kinase	0.007	0.0035	0.0708
Entamoeba histolytica	protein kinase, putative	0.007	0.0035	0.1619
Echinococcus granulosus	histone acetyltransferase KAT2B	0.0152	0.0144	0.0144
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0063	0.0026	0.0526
Trypanosoma cruzi	Bromodomain, putative	0.0063	0.0026	0.3417
Brugia malayi	Bromodomain containing protein	0.0063	0.0026	0.0026
Plasmodium vivax	bromodomain protein, putative	0.0063	0.0026	0.0708
Trichomonas vaginalis	conserved hypothetical protein	0.0063	0.0026	0.0526
Loa Loa (eye worm)	acetyltransferase	0.0385	0.0453	0.0453
Echinococcus multilocularis	Bromodomain containing protein	0.0208	0.0219	0.0219
Entamoeba histolytica	PH domain containing protein kinase, putative	0.0056	0.0017	0.0793
Onchocerca volvulus		0.0076	0.0044	0.0898
Brugia malayi	hypothetical protein	0.0522	0.0635	0.0635
Trichomonas vaginalis	conserved hypothetical protein	0.0063	0.0026	0.0526
Plasmodium falciparum	glycogen synthase kinase 3	0.0076	0.0044	0.6106
Plasmodium falciparum	bromodomain protein, putative	0.0063	0.0026	0.2086
Schistosoma mansoni	gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2	0.0385	0.0453	0.0453
Schistosoma mansoni	zinc finger protein	0.0141	0.013	0.013
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0208	0.0219	0.4373
Trichomonas vaginalis	conserved hypothetical protein	0.0063	0.0026	0.0526
Trichomonas vaginalis	conserved hypothetical protein	0.0063	0.0026	0.0526
Brugia malayi	Serine/threonine-protein kinase F42G10.2	0.018	0.0181	0.0181
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0208	0.0219	0.4373
Giardia lamblia	Transcription regulatory protein SNF2	0.0063	0.0026	0.0446
Echinococcus multilocularis	dual specificity mitogen activated protein	0.018	0.0181	0.0181
Plasmodium vivax	SET domain containing protein	0.0063	0.0026	0.0708
Trypanosoma cruzi	bromodomain-containing protein 3	0.0063	0.0026	0.3417
Trichomonas vaginalis	conserved hypothetical protein	0.0063	0.0026	0.0526
Trichomonas vaginalis	conserved hypothetical protein	0.0063	0.0026	0.0526
Toxoplasma gondii	SWI2/SNF2 Brahma-like putative	0.0087	0.0058	0.1637
Brugia malayi	Protein kinase domain containing protein	0.007	0.0035	0.0035
Schistosoma mansoni	glycogen synthase kinase 3-related (gsk3) (cmgc group III)	0.0076	0.0044	0.0044
Plasmodium vivax	bromodomain protein, putative	0.0063	0.0026	0.0708
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0063	0.0026	0.0526
Loa Loa (eye worm)	hypothetical protein	0.0063	0.0026	0.0026
Trichomonas vaginalis	conserved hypothetical protein	0.0063	0.0026	0.0526
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0276	0.0308	0.6153
Schistosoma mansoni	hypothetical protein	0.0094	0.0067	0.0067
Trichomonas vaginalis	cat eye syndrome critical region protein 2, cscr2, putative	0.0152	0.0144	0.2879
Trichomonas vaginalis	conserved hypothetical protein	0.0063	0.0026	0.0526
Echinococcus granulosus	bromodomain containing 2	0.0421	0.0501	0.0501
Trichomonas vaginalis	hypothetical protein	0.0063	0.0026	0.0526
Toxoplasma gondii	histone lysine acetyltransferase GCN5-A	0.0152	0.0144	0.6116
Brugia malayi	PHD-finger family protein	0.0292	0.033	0.033
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0421	0.0501	1
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0063	0.0026	0.0526
Brugia malayi	Bromodomain containing protein	0.0063	0.0026	0.0026
Entamoeba histolytica	protein kinase 2, putative	0.0056	0.0017	0.0793
Entamoeba histolytica	bromodomain-containing protein	0.0063	0.0026	0.1204
Echinococcus granulosus	serine threonine protein kinase nrc	0.0056	0.0017	0.0017
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0208	0.0219	0.4373
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0063	0.0026	0.0526
Loa Loa (eye worm)	BRM protein	0.0097	0.0072	0.0072
Schistosoma mansoni	hypothetical protein	0.0063	0.0026	0.0026
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0063	0.0026	0.0526
Trichomonas vaginalis	conserved hypothetical protein	0.0063	0.0026	0.0526
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0208	0.0219	0.4373
Schistosoma mansoni	hypothetical protein	0.0063	0.0026	0.0026
Echinococcus multilocularis	PH interacting protein	0.0063	0.0026	0.0026
Trichomonas vaginalis	conserved hypothetical protein	0.0063	0.0026	0.0526
Trichomonas vaginalis	conserved hypothetical protein	0.0063	0.0026	0.0526
Trichomonas vaginalis	conserved hypothetical protein	0.0063	0.0026	0.0526
Giardia lamblia	Histone acetyltransferase GCN5	0.0089	0.006	0.2136
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0063	0.0026	0.0526
Trypanosoma brucei	ISWI complex protein	0.007	0.0035	0.4922
Entamoeba histolytica	protein kinase domain containing protein	0.0076	0.0044	0.1994
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0421	0.0501	1
Echinococcus granulosus	bromodomain containing protein 8	0.0063	0.0026	0.0026
Leishmania major	glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270	0.0076	0.0044	1
Schistosoma mansoni	bromodomain containing protein	0.0253	0.0278	0.0278
Schistosoma mansoni	acetyl-CoA C-acetyltransferase	0.0102	0.0079	0.0079
Trichomonas vaginalis	histone acetyltransferase gcn5, putative	0.0064	0.0028	0.0557
Trichomonas vaginalis	AGC family protein kinase	0.007	0.0035	0.0708
Schistosoma mansoni	hypothetical protein	0.0063	0.0026	0.0026
Trichomonas vaginalis	conserved hypothetical protein	0.0063	0.0026	0.0526
Plasmodium falciparum	histone acetyltransferase GCN5	0.0089	0.006	1
Brugia malayi	Bromodomain containing protein	0.0421	0.0501	0.0501
Loa Loa (eye worm)	CMGC/GSK protein kinase	0.0076	0.0044	0.0044
Trichomonas vaginalis	conserved hypothetical protein	0.0063	0.0026	0.0526
Trichomonas vaginalis	conserved hypothetical protein	0.0063	0.0026	0.0526
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0063	0.0026	0.0526
Loa Loa (eye worm)	CBP-B	0.0219	0.0233	0.0233
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0063	0.0026	0.0526
Echinococcus multilocularis	zinc finger protein	0.0141	0.013	0.013
Trichomonas vaginalis	bromodomain and PHD finger-containing protein, putative	0.0063	0.0026	0.0526
Loa Loa (eye worm)	hypothetical protein	0.015	0.0142	0.0142
Trichomonas vaginalis	conserved hypothetical protein	0.0063	0.0026	0.0526
Trichomonas vaginalis	AGC family protein kinase	0.007	0.0035	0.0708
Loa Loa (eye worm)	AGC/RSK/P70 protein kinase	0.007	0.0035	0.0035
Brugia malayi	Bromodomain containing protein	0.0063	0.0026	0.0026
Trichomonas vaginalis	conserved hypothetical protein	0.0063	0.0026	0.0526
Echinococcus granulosus	bromodomain adjacent to zinc finger domain	0.0198	0.0205	0.0205
Echinococcus multilocularis		0.0063	0.0026	0.0026
Entamoeba histolytica	bromodomain-containing protein	0.0208	0.0219	1
Loa Loa (eye worm)	hypothetical protein	0.0063	0.0026	0.0026
Entamoeba histolytica	bromodomain-containing protein	0.0208	0.0219	1
Trypanosoma cruzi	bromodomain factor 2 protein	0.0063	0.0026	0.3417
Trypanosoma cruzi	ISWI complex protein	0.007	0.0035	0.6657
Trichomonas vaginalis	histone acetyltransferase gcn5, putative	0.0064	0.0028	0.0557
Echinococcus granulosus	calcium:calmodulin dependent protein kinase	0.0056	0.0017	0.0017
Plasmodium vivax	bromodomain protein, putative	0.0063	0.0026	0.0708
Schistosoma mansoni	serine/threonine-protein kinase	0.0056	0.0017	0.0017
Schistosoma mansoni	hypothetical protein	0.007	0.0035	0.0035
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0063	0.0026	0.0526
Echinococcus multilocularis	glycogen synthase kinase 3 beta	0.0076	0.0044	0.0044
Trichomonas vaginalis	bromodomain-containing protein 4, brd4, putative	0.0208	0.0219	0.4373
Trichomonas vaginalis	conserved hypothetical protein	0.0063	0.0026	0.0526
Echinococcus granulosus	acetyl coenzyme A C acetyltransferase	0.0126	0.011	0.011
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0063	0.0026	0.0526
Trichomonas vaginalis	conserved hypothetical protein	0.0208	0.0219	0.4373
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0208	0.0219	0.4373
Echinococcus granulosus	Bromodomain containing protein	0.0063	0.0026	0.0026
Trichomonas vaginalis	conserved hypothetical protein	0.0063	0.0026	0.0526
Entamoeba histolytica	acetyltransferase, GNAT family	0.0089	0.006	0.2759
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0208	0.0219	0.4373
Schistosoma mansoni	CREB-binding protein 2	0.0289	0.0327	0.0327
Echinococcus multilocularis	ATPase family AAA domain containing protein 2B	0.0063	0.0026	0.0026
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0063	0.0026	0.0526
Trichomonas vaginalis	conserved hypothetical protein	0.0063	0.0026	0.0526
Echinococcus granulosus	fetal alzheimer antigen falz	0.0102	0.0079	0.0079
Brugia malayi	ATPase, AAA family protein	0.0063	0.0026	0.0026
Echinococcus granulosus	Bromodomain containing protein	0.0063	0.0026	0.0026
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0063	0.0026	0.0526
Loa Loa (eye worm)	BRM protein	0.0138	0.0126	0.0126
Entamoeba histolytica	ankyrin repeat protein, putative	0.0063	0.0026	0.1204
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0276	0.0308	0.6153
Loa Loa (eye worm)	hypothetical protein	0.0063	0.0026	0.0026
Trichomonas vaginalis	conserved hypothetical protein	0.0063	0.0026	0.0526
Brugia malayi	TAZ zinc finger family protein	0.0289	0.0327	0.0327
Trichomonas vaginalis	hypothetical protein	0.0063	0.0026	0.0526
Trichomonas vaginalis	bromodomain containing protein, putative	0.0063	0.0026	0.0526
Plasmodium vivax	histone acetyltransferase GCN5, putative	0.0152	0.0144	1
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0208	0.0219	0.4373
Brugia malayi	Bromodomain containing protein	0.0063	0.0026	0.0026
Schistosoma mansoni	helicase	0.0212	0.0224	0.0224
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0063	0.0026	0.0526
Echinococcus multilocularis	gcn5proteinral control of amino acid synthesis	0.0385	0.0453	0.0453
Trichomonas vaginalis	AGC family protein kinase	0.007	0.0035	0.0708
Loa Loa (eye worm)	hypothetical protein	0.0063	0.0026	0.0026
Trichomonas vaginalis	bromodomain containing protein, putative	0.0208	0.0219	0.4373
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0063	0.0026	0.0526
Brugia malayi	acetyltransferase, GNAT family protein	0.0385	0.0453	0.0453
Trypanosoma cruzi	ISWI complex protein	0.007	0.0035	0.6657
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0063	0.0026	0.0526
Echinococcus multilocularis	CREB binding protein	0.0217	0.0231	0.0231
Echinococcus multilocularis	fetal alzheimer antigen, falz	0.0229	0.0246	0.0246
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0208	0.0219	0.4373
Trichomonas vaginalis	bromodomain containing protein, putative	0.0063	0.0026	0.0526
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0063	0.0026	0.0526
Loa Loa (eye worm)	hypothetical protein	0.0864	0.1089	0.1089
Echinococcus multilocularis	rac serine:threonine kinase	0.0056	0.0017	0.0017
Schistosoma mansoni	hypothetical protein	0.0063	0.0026	0.0026
Toxoplasma gondii	cell-cycle-associated protein kinase GSK, putative	0.0076	0.0044	0.0898
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0063	0.0026	0.0526
Trichomonas vaginalis	CMGC family protein kinase	0.0076	0.0044	0.0872
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0208	0.0219	0.4373
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0208	0.0219	0.4373
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0208	0.0219	0.4373
Echinococcus granulosus	serine/threonine protein kinase	0.0056	0.0017	0.0017
Echinococcus multilocularis	bromodomain containing protein 8	0.0063	0.0026	0.0026
Giardia lamblia	Hypothetical protein	0.0063	0.0026	0.0446
Trypanosoma cruzi	Bromodomain, putative	0.0063	0.0026	0.3417
Trichomonas vaginalis	histone acetyltransferase gcn5, putative	0.0063	0.0026	0.0526
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0063	0.0026	0.0526
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0063	0.0026	0.0526
Trichomonas vaginalis	conserved hypothetical protein	0.0063	0.0026	0.0526
Trichomonas vaginalis	conserved hypothetical protein	0.0063	0.0026	0.0526
Schistosoma mansoni	polybromo-1	0.0063	0.0026	0.0026
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0063	0.0026	0.0526
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0063	0.0026	0.0526
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0063	0.0026	0.0526
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0063	0.0026	0.0526
Echinococcus multilocularis	protein kinase shaggy	0.0076	0.0044	0.0044
Trichomonas vaginalis	CMGC family protein kinase	0.0076	0.0044	0.0872
Leishmania major	hypothetical protein, conserved	0.007	0.0035	0.4922
Echinococcus multilocularis	bromodomain adjacent to zinc finger domain	0.0163	0.0159	0.0159
Echinococcus granulosus	CREB binding protein	0.0201	0.021	0.021
Entamoeba histolytica	hypothetical protein	0.0063	0.0026	0.1204
Schistosoma mansoni	CREB-binding protein 1 (SmCBP1)	0.0289	0.0327	0.0327
Entamoeba histolytica	bromodomain-containing protein	0.0063	0.0026	0.1204
Trichomonas vaginalis	conserved hypothetical protein	0.0063	0.0026	0.0526
Trichomonas vaginalis	bromodomain-containing protein 3, brd3, putative	0.0063	0.0026	0.0526
Echinococcus granulosus	ATPase family AAA domain containing protein 2B	0.0063	0.0026	0.0026
Onchocerca volvulus	Kinase homolog	0.018	0.0181	0.8026
Echinococcus granulosus	dual specificity mitogen activated protein	0.7578	1	1
Brugia malayi	Bromodomain containing protein	0.0267	0.0297	0.0297
Echinococcus granulosus	global transcription activator snf2l2	0.0212	0.0224	0.0224
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0063	0.0026	0.0526
Trichomonas vaginalis	bromodomain containing protein, putative	0.0276	0.0308	0.6153
Trichomonas vaginalis	AGC family protein kinase	0.007	0.0035	0.0708
Echinococcus multilocularis	global transcription activator snf2l2	0.0212	0.0224	0.0224
Schistosoma mansoni	protein kinase	0.7578	1	1
Echinococcus granulosus	bromodomain containing protein 7	0.0356	0.0415	0.0415
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0276	0.0308	0.6153
Echinococcus multilocularis	dual specificity mitogen activated protein	0.7578	1	1
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0208	0.0219	0.4373
Echinococcus granulosus	transcription initiation factor TFIID subunit 1	0.0063	0.0026	0.0026
Brugia malayi	Bromodomain containing protein	0.0798	0.1001	0.1001
Echinococcus granulosus	PH interacting protein	0.0063	0.0026	0.0026
Loa Loa (eye worm)	STE/STE7/MEK7 protein kinase	0.7578	1	1
Entamoeba histolytica	bromodomain-containing protein	0.0063	0.0026	0.1204
Schistosoma mansoni	serine/threonine-protein kinase	0.0056	0.0017	0.0017
Plasmodium falciparum	bromodomain protein 2, putative	0.0063	0.0026	0.2086
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0063	0.0026	0.0526
Loa Loa (eye worm)	hypothetical protein	0.0798	0.1001	0.1001
Echinococcus granulosus	polybromo 1	0.0063	0.0026	0.0026
Echinococcus granulosus	zinc finger protein	0.0141	0.013	0.013
Schistosoma mansoni	phd finger protein	0.0063	0.0026	0.0026
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0063	0.0026	0.0526
Plasmodium vivax	glycogen synthase kinase 3, putative	0.0076	0.0044	0.2073
Schistosoma mansoni	bromodomain-containing protein 3 brd3	0.0421	0.0501	0.0501
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0063	0.0026	0.0526
Echinococcus multilocularis	polybromo 1	0.0063	0.0026	0.0026
Echinococcus granulosus	glycogen synthase kinase 3 beta	0.0076	0.0044	0.0044
Loa Loa (eye worm)	STE/STE7/MEK4 protein kinase	0.018	0.0181	0.0181
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0063	0.0026	0.0526
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0152	0.0144	0.2879
Loa Loa (eye worm)	hypothetical protein	0.0198	0.0206	0.0206
Trichomonas vaginalis	bromodomain containing protein, putative	0.0063	0.0026	0.0526
Echinococcus multilocularis	Bromodomain containing protein	0.0063	0.0026	0.0026
Schistosoma mansoni	zinc finger protein	0.007	0.0035	0.0035
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0063	0.0026	0.0526
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0063	0.0026	0.0526
Echinococcus granulosus	protein kinase C binding protein 1	0.0063	0.0026	0.0026
Trichomonas vaginalis	conserved hypothetical protein	0.0063	0.0026	0.0526
Trichomonas vaginalis	conserved hypothetical protein	0.0063	0.0026	0.0526
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0208	0.0219	0.4373
Trichomonas vaginalis	AGC family protein kinase	0.007	0.0035	0.0708
Echinococcus multilocularis	peregrin	0.0063	0.0026	0.0026
Giardia lamblia	Kinase, CMGC GSK	0.0076	0.0044	0.1304
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0063	0.0026	0.0526
Echinococcus multilocularis	acetyl coenzyme A C acetyltransferase	0.0126	0.011	0.011
Brugia malayi	p70 ribosomal S6 kinase beta	0.007	0.0035	0.0035
Toxoplasma gondii	AGC kinase	0.007	0.0035	0.0473
Echinococcus granulosus	CREB binding protein	0.0289	0.0327	0.0327
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0208	0.0219	0.4373
Brugia malayi	polybromodomain protein	0.0063	0.0026	0.0026
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0208	0.0219	0.4373
Echinococcus granulosus	dual specificity mitogen activated protein	0.018	0.0181	0.0181
Schistosoma mansoni	kinase	0.018	0.0181	0.0181
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0063	0.0026	0.0526
Toxoplasma gondii	histone lysine acetyltransferase GCN5-B	0.0152	0.0144	0.6116
Loa Loa (eye worm)	hypothetical protein	0.0063	0.0026	0.0026
Brugia malayi	Bromodomain containing protein	0.0864	0.1089	0.1089
Schistosoma mansoni	bromodomain containing	0.0419	0.0499	0.0499
Plasmodium falciparum	bromodomain protein 1	0.0063	0.0026	0.2086
Onchocerca volvulus		0.0208	0.0219	1
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0063	0.0026	0.0526
Trypanosoma cruzi	Bromodomain, putative	0.0063	0.0026	0.3417
Loa Loa (eye worm)	hypothetical protein	0.0063	0.0026	0.0026
Trichomonas vaginalis	histone acetyltransferase gcn5, putative	0.0063	0.0026	0.0526
Entamoeba histolytica	protein kinase, putative	0.0076	0.0044	0.1994
Loa Loa (eye worm)	hypothetical protein	0.0108	0.0086	0.0086
Echinococcus granulosus	peregrin	0.0063	0.0026	0.0026
Trichomonas vaginalis	conserved hypothetical protein	0.0276	0.0308	0.6153
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0063	0.0026	0.0526
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0063	0.0026	0.0526
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0208	0.0219	0.4373
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0208	0.0219	0.4373
Brugia malayi	Bromodomain containing protein	0.0226	0.0243	0.0243
Plasmodium vivax	conserved Plasmodium protein, unknown function	0.0063	0.0026	0.0708
Trichomonas vaginalis	conserved hypothetical protein	0.0063	0.0026	0.0526
Loa Loa (eye worm)	hypothetical protein	0.0159	0.0154	0.0154
Trichomonas vaginalis	AGC family protein kinase	0.007	0.0035	0.0708
Trichomonas vaginalis	conserved hypothetical protein	0.0063	0.0026	0.0526
Loa Loa (eye worm)	bromodomain containing protein	0.0133	0.0119	0.0119
Echinococcus multilocularis	bromodomain adjacent to zinc finger domain	0.0198	0.0205	0.0205
Echinococcus granulosus	bromodomain adjacent to zinc finger domain	0.0163	0.0159	0.0159
Loa Loa (eye worm)	PHD-finger family protein	0.0258	0.0286	0.0286
Trypanosoma cruzi	glycogen synthase kinase 3, putative	0.0076	0.0044	1
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0208	0.0219	0.4373
Schistosoma mansoni	bromodomain containing protein	0.0072	0.0038	0.0038
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0063	0.0026	0.0526
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0063	0.0026	0.0526
Loa Loa (eye worm)	AGC/AKT protein kinase	0.007	0.0035	0.0035
Echinococcus multilocularis	serine threonine protein kinase nrc serine threonine protein kinase gad	0.0056	0.0017	0.0017
Echinococcus granulosus	protein kinase shaggy	0.0076	0.0044	0.0044
Echinococcus multilocularis	bromodomain containing 2	0.0421	0.0501	0.0501
Trichomonas vaginalis	histone acetyltransferase gcn5, putative	0.0063	0.0026	0.0526
Trypanosoma cruzi	Bromodomain factor 1	0.0063	0.0026	0.3417

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

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External resources for this compound

ChEMBL: CHEMBL3039639

Bibliographic References

No literature references available for this target.

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Detailed information for compound 1791313